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Gonadal dysfunction, the most frequent endocrine complication in both sexes after autologous hematopoietic cell transplant (HCT) could increase bone loss and sarcopenia, a disease characterized by reduced muscle strength and mass. Sarcopenia is associated with worse survival, lower remission rates, and progression-free survival in patients with lymphoma after HCT. Low bone mass affected approximately 20% of the transplanted patients within 2 years and harms quality of life. This study was conducted in a single center and identified a strong relationship with patients transplanted more recently by LEC (lomustine, etoposide, and cyclophosphamide) conditioning regimen with sarcopenia. Peripheral neuropathy and bone mass changes were also associated with sarcopenia as well, suggesting a relationship with muscle strength loss., (© 2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Objective: To map the technical and managerial strategies for the management and reduction of airborne particles production in surgical procedures settings during the Covid-19 pandemic., Method: Scoping review, according to the Joana Briggs Institute methodology, based on documents indexed in MEDLINE, VHL, CINAHL Cochrane, Embase, Scopus, Web of Science, and gray literature, published in Portuguese, English, or Spanish. All studies from indexed scientific journals and recommendations published by international agencies or academic associations from 2019 to January 2022 were considered. Findings were summarized and analyzed using descriptive statistics and narrative synthesis., Results: Twenty-two studies were selected, 19 of which were published in English, two in Spanish, one in Portuguese, with a predominance of literature reviews. Findings were categorized into recommendations for the environment, the team, and the surgical technique., Conclusion: The review mapped the technical and managerial strategies for the management and reduction of the airborne particles production in surgical procedures settings. They involve from the use of personal protective equipment, training, anesthetic modality, airway manipulation, to the execution of the surgical technique.

Objective: to assess cardiovascular risk among nursing workers at a public hospital., Method: a cross-sectional study, with 324 nursing workers, using a questionnaire composed of two information blocks. The first covered issues related to sociodemographic and occupational and health characteristics, and the second, the Revised Framingham Risk Score (FRS), to stratify cardiovascular risk. To assess work-related psychosocial stress, the Swedish Social Control Demand Scale was used., Results: the most prevalent modifiable risk factor for CVDs was waist circumference (75.9%), followed by overweight (43.8%), obesity (29.3%), alcohol consumption (21.9%), lipoprotein cholesterol low density (LDL) > 130 (20.7%) and hypertension (20.4%)., Conclusion: it was found that 96% of workers had a low risk of developing cardiovascular disease in the next ten years, and male workers aged >40 years with shorter working hours are more likely to have cardiovascular disease.

Objective: To present the JBI evidence implementation methodology and report the Brazilian experience in educating health professionals., Method: This is an experience report on professional education in the Brazilian context as per the JBI methodology., Results: In four years, 29 clinical fellows were trained in Brazil, with technical and scientific theoretical bases and tools for evidence-based practice, focusing on the transformation of the health contexts in which they are inserted., Conclusion: The JBI methodology offers systems and tools to evaluate existent practices; it also reinforces and disseminates evidence-based healthcare, potentializing the achievement of effective change in healthcare.

Objective: to investigate symptoms of depression and anxiety and their association with the sociodemographic characteristics of undergraduate nursing students., Methods: a cross-sectional analytical study carried out with students from the Faculty of Nursing at Universidade Federal de Juiz de Fora from June to July 019. Data were collected through a sociodemographic questionnaire and the Beck Depression and Anxiety Inventories., Results: 192 students participated, with a mean age of 21.44 (±3.56) years. 85.93% of participants were female. The mean depression score was 22.40 (±12.35), and anxiety was 17.56 (±11.98). There was a difference in the mean of the scales for sex and psychotropic drugs (p<0.05). Women presented moderate and severe classification for both scales. Severe symptoms prevailed among students from the 6th to the 10th semester (18.22%)., Conclusion: there was an association between depression and anxiety symptoms related to gender and psychotropic drugs.

Objectives: to construct and assess bundle content for the prevention and management of complications in neutropenia in cancer patients., Methods: a methodological study developed in four stages: scoping review; bundle construction; material assessment by experts (developed according to Pasquali's psychometry); pilot test in a High Complexity Assistance Unit in Oncology. For content assessment, the Delphi technique was applied in two rounds and those items with Content Validation Coefficient (CVC)> 0.78 and agreement> 80.0% were considered valid. Data were analyzed using descriptive and inferential statistics., Results: all bundle requirements reached agreement between judges above 80.0%, in addition to statistically significant levels of assessment. At the end of the Delphi technique, bundle was significantly valid with CVC = 0.92 and CVC = 0.93, respectively., Conclusions: bundle content proved to be valid and highly credible.

Purpose : The aim of this study was to determine changes in swimming parameters, stroke coordination, and symmetry after repeated high-intensity swimming efforts in swimmers of different performance levels and para-swimmers. Method : Forty swimmers (20 able-bodied, allocated to higher and lower performance groups-G1 and G2, respectively-and 20 impaired swimmers-S5 to S10) were recorded by four underwater cameras while performing repeated 50 m maximum front-crawl swimming with a ten-second interval for each time endured by the swimmer. A cycle stroke was digitized using SIMI Reality Motion Systems in the first and last trials to analyze the kinematic parameters. The comparison among groups and conditions was performed by Mixed ANOVA Models with p < .05. Results : For all groups, swimming velocity, stroke rate, and stroke index showed reduction over time, while stroke length and intracyclic velocity variation did not show significant changes. Conclusions : Training to maintain stroke rate is necessary to support performance since it is the main cause of velocity decrease. Stroke dimensions and individual underwater phases were not sufficient to distinguish groups or conditions. Hand velocity decreased probably due to a decline in energy capacity, propulsive force and passive drag caused by the fatigue process.

Objective: to evaluate the knowledge of basic education students before and after educational intervention on Basic Life Support in a situation of adult cardiorespiratory arrest., Method: quasi-experimental study conducted with 335 students from three elementary schools. Data was collected using an instrument that captured sociodemographic data and knowledge about Basic Life Support. Subsequently, they were analyzed by descriptive and analytical statistics., Results: students' knowledge in the post-test (p <0.05) was significantly higher than in the pre-test. The average of the pre-test scores was 4.12 ± 1.7 and, in the post-test it was 6.53 ± 1.9 (p = 0.00)., Conclusion: the results demonstrated effectiveness of the intervention with the expansion of knowledge about Basic Life Support in cardiorespiratory arrest. The results reinforce the importance of Nursing in health education actions in elementary schools.

Objective: To evaluate whether methylene blue (MB) could minimize the effects of ischemia-reperfusion injury in the nonischemic lung on a lung transplantation rodent model., Methods: Forty female Sprague-Dawley rats were divided into 20 donors and 20 recipients. The 20 recipient rats were divided into two groups (n = 10) according to the treatment (0.9% saline vs. 1% MB solutions). All animals underwent unilateral lung transplantation. Recipients received 2 mL of saline or MB intraperitoneally prior to transplantation. After 2 h of reperfusion, the animals were euthanized and histopathological and immunohistochemical analyses were performed in the nonischemic lung., Results: There was a significant decrease in inflammation-neutrophil count and intercellular adhesion molecule-1 (ICAM-1) expression in lung parenchyma were higher in the saline group in comparison with the MB group-and in apoptosis-caspase-3 expression was higher in the saline group and Bcl-2 expression was higher in MB group., Conclusions: MB is an effective drug for the protection of nonischemic lungs against inflammation and apoptosis following unilateral lung transplantation in rats.