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In this paperwe share the behind-the-scenes story of the development of our paper "When worlds collide: The internal dynamics of organizational responses to conflicting institutional demands," which received the 2020 Academy of Management Review Decade Award. Furthermore, 10 years into its publication, we assess the degree towhich the phenomenonof conflicting institutionaldemands is still prevalent today. Wefurtherpushour theorizing, extending our initial model of the determinants of organizational responses to institutional complexity by discussing the potential consequences of these responses and outlining the organizational factors that may enable their successful enactment. [ABSTRACT FROM AUTHOR]

In order to achieve a more efficient allocation of healthcare resources in the near future, it is crucial to understand the patterns and causes of excess mortality and hospitalizations. Neonatal mortality still poses a significant challenge, particularly in developed nations where the mortality rates are already low and healthcare resources are generally available to most of the population. Furthermore, the low mortality rates mean that the data available for modeling are often very limited, restricting the modeling methods that can be used. It is also important that the chosen methods allow for explainable, non-black-box models that can be interpreted by healthcare professionals. Considering these challenges, the work hereby presented thoroughly analyzed the time series of the neonatal mortality rates in Portugal between 2014 and 2019 in terms of trend and seasonal patterns. The applicability and performance of different data-based methods were also analyzed. Furthermore, the mortality rates were studied in terms of their relation to environmental variables, such as temperature and air pollution indicators, with the goal of establishing causal relations between such variables and excess mortality. The preliminary results show that ARMA, neural and fuzzzy models are able to forecast the studied mortality rates with good performance. In particular, neural models have the best predictive performance, while fuzzy models are well suited to obtain interpretable models with acceptable performance. [ABSTRACT FROM AUTHOR]

This paper explores the most effective learning strategies for pharmaceutical companies within their knowledge environment.

Hybrid organizations pursuing a social mission while relying on a commercial business model have paved the way for a new approach to achieving societal impact. Although they bear strong promise, social enterprises are also fragile organizations that must walk a fine line between achieving a social mission and living up to the requirements of the market. This article moves beyond generic recommendations about managing hybrids in order to highlight a typology of social business hybrids and discuss how each of the four proposed types of hybrid organizations can be managed in order to avoid the danger of mission drift and better achieve financial sustainability. [ABSTRACT FROM AUTHOR]

We examine how entrepreneurs shape organizational boundaries and construct markets through an inductive, longitudinal study of five ventures. Our central contribution is a framework of how successful entrepreneurs attempt to dominate nascent markets by co-constructing organizational boundaries and market niches using three processes: claiming, demarcating, and controlling a market. We propose that power is the underlying boundary logic and indicate the "soft-power" strategies by which entrepreneurs compete in highly ambiguous markets. Overall, we develop a holistic view of organizational boundaries and offer insights into institutional entrepreneurship and resource dependence theories. Our most important contribution is reinvigorating the study of interorganizational power. [ABSTRACT FROM AUTHOR]

Byline: Filipe M. Santos The knowledge management field has been mostly the domain of consultants, practitioners, and information systems theorists. This field has evolved largely divorced from the more scholarly areas of research on knowledge, which include studies in the social psychology, organisational and sociology fields. Grounded on scholarly research in these disciplines, this paper analyses and critiques the dominant practices and prescriptions of knowledge management programs. The paper then presents a view on the elements of an optimal knowledge management system and specifies the role that technology should play in such a system.

Natural products have been used since ancient times to produce medicines. Nowadays, there are plenty of chemotherapeutic drugs obtained from natural sources and used against a plethora of diseases. Unfortunately, most of these compounds often display systemic toxicity and adverse effects. In order to better evaluate the tolerability of selected potentially bioactive samples, brine shrimp (Artemia salina) is generally used as a model in lethality studies. The A. salina test is based on the ability of the studied bioactive compounds to kill the microcrustaceans in their larval stage (nauplii). This method represents a convenient starting point for cytotoxicity studies, as well as for the general toxicity screening of synthetic, semisynthetic, and natural products. It can be considered a simple, quick, and low-cost assay, compared to many other assays (in vitro cells or yeast strains, zebrafish, rodents) generally suitable for the aforementioned purposes; moreover, it can be easily performed even without any specific training. Overall, A. salina assay represents a useful tool for the preliminary toxicity evaluation of selected compounds and the bio-guided fractionation of natural product extracts.