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1. FRI-472-YI Mitochondrial metabolism is disrupted by ciprofloxacin preventing cholangiocarcinoma cell proliferation

2. THU-210 Dysfunctional activation of the DNA damage response is associated with MASLD progression through an E2F2-dependent mechanism

3. FRI-343-YI APAP induced liver damage is prevented by activation of PPARgamma and PPAR-alpha

4. OS-101-YI Remodelling of hepatocyte cholesterol metabolism mediates colorectal liver metastasis

5. TOP-229-YI The E2F2 target glycerophosphodiester phosphodiesterase domain containing 3 is involved in MASLD progression to HCC and related dyslipidemias

6. The E2F2-miR34a-5p axis is involved in the biliary metabolism dysregulation in NASH

7. Microbiota-targeted interventions in the gut-liver axis for chronic liver disease of DUAL etiology

8. Targeting the E2F/MCM axis in cholangiocarcinoma halts disease progression in experimental models by rewiring lipid metabolism

9. E2F2 deficiency protects from acetaminophen-induced hepatotoxicity while E2F1 is required to prevent the devastating effects

10. E2F2-promoted DNA damage in NASH worsens the metabolic scenario

11. The uptake of extracellular lipids promotes cholangiocarcinoma progression

12. miR34a-5p is a target of E2F2 transcription factor in MAFLD-related HCC

13. Methionine adenosyltransferase 1a antisense oligonucleotides induce the fibroblast growth factor 21-driven recovery from obesity and associated hepatoesteatosis

14. The DNA damage response is involved in the metabolic dysregulation of MAFLD patients via inefficient fatty acid oxidation

15. WED-408 - E2F2-promoted DNA damage in NASH worsens the metabolic scenario

16. WED-404 - The E2F2-miR34a-5p axis is involved in the biliary metabolism dysregulation in NASH

17. SAT-215 - Targeting the E2F/MCM axis in cholangiocarcinoma halts disease progression in experimental models by rewiring lipid metabolism

18. THU-235 - Microbiota-targeted interventions in the gut-liver axis for chronic liver disease of DUAL etiology

19. FRI-395 - E2F2 deficiency protects from acetaminophen-induced hepatotoxicity while E2F1 is required to prevent the devastating effects

20. FRI-294-Mitochondrial GNMT-complex II is recovered by miR-873-5p targeting in NAFLD

21. PS-015-Role of methylation-controlled J-protein, endogenous repressor of the mitochondrial respiratory chain, in cholestatic liver disease

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