45 results on '"Santini, Conrad"'
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2. Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery
3. Design and construction of a stereochemically diverse piperazine-based DNA-encoded chemical library
4. Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes†
5. Practical and scalable synthesis of orthogonally protected-2-substituted chiral piperazines
6. Absolute stereochemistry of the squalene synthase inhibitor zaragozic acid C
7. Correction to Synthesis of Enantiomerically Pure 6-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production
8. Synthesis of Enantiomerically Pure 5-Substituted Piperazine-2-Acetic Acid Esters as Intermediates for Library Production
9. Activation of PPARδ alters lipid metabolism in db/db mice
10. Synthesis of Enantiomerically Pure 3-Substituted Piperazine-2-acetic Acid Esters as Intermediates for Library Production
11. Synthesis of Enantiomerically Pure 6-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production
12. Constrained TRPV1 agonists synthesized via silver-mediated intramolecular azo-methine ylide cycloaddition of α-iminoamides
13. Design of potent and selective GPR119 agonists for type II diabetes
14. Tris(phenylthio)methyllithium
15. Diversity by Divergence: Solution-Phase Parallel Synthesis of a Library of N-Diversified 1-Oxa-7-Azaspiro[4.5]decan-2-yl-Propanes and -Butanes
16. Synthesis of a Family of Spirocyclic Scaffolds: Building Blocks for the Exploration of Chemical Space
17. Skeletal Diversification via Heteroatom Linkage Control: Preparation of Bicyclic and Spirocyclic Scaffolds from N-Substituted Homopropargyl Alcohols
18. Solution-Phase Synthesis of a Diverse Library of Benzisoxazoles Utilizing the [3 + 2] Cycloaddition of in Situ-Generated Nitrile Oxides and Arynes
19. Automated Synthesis of a Library of Triazolated 1,2,5-Thiadiazepane 1,1-Dioxides via a Double Aza-Michael Strategy
20. ChemInform Abstract: In situ Generation and Intramolecular Schmidt Reaction of Keto Azides in a Microwave‐Assisted Flow Format.
21. Tris(phenylthio)methane
22. Synthesis of Amino-Benzothiaoxazepine-1,1-dioxides Utilizing a Microwave-Assisted, SNAr Protocol
23. Triazole-Containing Isothiazolidine 1,1-Dioxide Library Synthesis: One-Pot, Multi-Component Protocols for Small Molecular Probe Discovery
24. In Situ Generation and Intramolecular Schmidt Reaction of Keto Azides in a Microwave‐Assisted Flow Format
25. Application of 6,7-Indole Aryne Cycloaddition and Pd(0)-Catalyzed Suzuki–Miyaura and Buchwald–Hartwig Cross-Coupling Reactions for the Preparation of Annulated Indole Libraries
26. Automated Synthesis of a 184-Member Library of Thiadiazepan-1,1-dioxide-4-ones
27. Design and synthesis of potent and subtype-selective PPARα agonists
28. Novel 2,3-Dihydrobenzofuran-2-carboxylic Acids: Highly Potent and Subtype-Selective PPARα Agonists with Potent Hypolipidemic Activity
29. Amphipathic 3-Phenyl-7-propylbenzisoxazoles; Human PPaR γ, δ and α Agonists.
30. Phenylacetic acid derivatives as hPPAR agonists
31. Amphipathic 3-Phenyl-7-propylbenzisoxazoles; human pPaR γ, δ and α agonists
32. Tris(phenylthio)methyllithium
33. Novel Peroxisome Proliferator-activated Receptor (PPAR) γ and PPARδ Ligands Produce Distinct Biological Effects
34. Diversity by Divergence: Solution-Phase Parallel Synthesis of a Library of A/-Diversified 1-Oxa-7-Azaspiro[4.5]decan-2-yl-Propanes and -Butanes.
35. Synthesis of Amino-Benzothiaoxazepine-1,1-dioxides Utilizing a Microwave-Assisted, SNAr Protocol.
36. Triazole-Containing Isothiazolidine 1,1 -Dioxide Library Synthesis: One-Pot, Multi-Component Protocols for Small Molecular Probe Discovery.
37. Application of 6,7-lndole Aryne Cycloaddition and Pd(0)-Catalyzed Suzuki-Miyaura and Buchwald-Hartwig Cross-Coupling Reactions for the Preparation of Annulated Indole Libraries.
38. Automated Synthesis of a 184-Member Library of Thiadiazepan-1, 1-dioxide-4-ones.
39. A cyclobutene bridgehead olefin approach to the germacranes
40. Cyclobutene bridgehead olefin route to the American cockroach sex pheromone, periplanone-B
41. ChemInform Abstract: In situ Generation and Intramolecular Schmidt Reaction of Keto Azides in a Microwave-Assisted Flow Format.
42. Mechanisms by which synthetic 6,7-annulated-4-substituted indole compounds with anti-proliferative activity disrupt mitosis and block cytokinesis in human HL-60 tumor cells in vitro.
43. Antitumor effects of synthetic 6,7-annulated-4-substituted indole compounds in L1210 leukemic cells in vitro.
44. In situ generation and intramolecular Schmidt reaction of keto azides in a microwave-assisted flow format.
45. Amphipathic 3-phenyl-7-propylbenzisoxazoles; human pPaR gamma, delta and alpha agonists.
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