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206 results on '"Sannolo, N"'

4. Non pulmonary effects of isocyanates

Author

Pedata P, Corvino A. R, Lamberti M, Petrarca C, Di Giampaolo L, Sannolo N. and Di Gioacchino M., Takemi Otsuki, Takemi Otsuki Claudia Petrarca Mario Di Gioacchino, Pedata, P, Corvino A., R, Lamberti, M, Petrarca, C, Di Giampaolo, L, and Sannolo, N. and Di Gioacchino M.

Published
2017

5. Mesotelioma Maligno

Author

Tomei, F., Candura, S. M., Sannolo, N., Sartorelli, P., Costa, G., Perbellini, L., LARESE FILON, F., Magrini, A., Bartolucci, G. B., Ricci, S., Ciocan, C, Pira, E, and Garzaro, G

Published
2018

6. Neoplasie occupazionali

Author

Tomei, F., Candura, S. M., Sannolo, N., Sartorelli, P., Costa, G., Perbellini, L., LARESE FILON, F., Magrini, A., Bartolucci, G. B., Ricci, S, Ciocan, C, Pira, E, and Garzaro, G

Published
2018

7. Linee guida per la sorveglianza in agricoltura

Author

Colosio, C, Angotzi, G, Ariano, E, Borghesi, S, Bovenzi, M, Gerardi, D, Gobba, F, L’Abbate, N, Lucchini, R, Maso, S, Mattioli, S, Messineo, A, Miraglia, N, Moretto, A, Musti, M, Occhipinti, E, Peretti, A, Romeo, L, Ronchese, F, Rubino, FM, Saldutti, E, Sannolo, N, Simonelli, A, Somaruga, C, Vellere, F, Vitelli, N., DE VITO, GIOVANNI, RIVA, MICHELE AUGUSTO, Colosio, C, Angotzi, G, Ariano, E, Borghesi, S, Bovenzi, M, DE VITO, G, Gerardi, D, Gobba, F, L’Abbate, N, Lucchini, R, Maso, S, Mattioli, S, Messineo, A, Miraglia, N, Moretto, A, Musti, M, Occhipinti, E, Peretti, A, Riva, M, Romeo, L, Ronchese, F, Rubino, F, Saldutti, E, Sannolo, N, Simonelli, A, Somaruga, C, Vellere, F, and Vitelli, N

Subjects
MED/44 - MEDICINA DEL LAVORO, Agriculture
Published
2013

9. Test Diagnostici per la Verifica dell’assunzione di Sostanze Stupefacenti nei Luoghi di Lavoro

Author

PIERI, MARIA, Basilicata P., Miraglia N., Liotti F., Sannolo N., ACAMPORA, ANTONIO, DELLA CASA, ELVIRA, Pieri, Maria, Basilicata, P., Miraglia, N., Liotti, F., Acampora, Antonio, Sannolo, N., and DELLA CASA, Elvira

Subjects
luoghi di lavoro, analisi di conferma, sostanze stupefacenti
Abstract

The Italian Legislative Decree 81/08 for health and safety protection at the workplaces contains an explicit mention to the need for the Occupational Physician Responsible (OPR) to integrate the Sanitary Surveillance with tests “aimed to verify the absence of alcohol dependence and drug assumption conditions” (article 41, comma 4). Such disposition highlights the crucial role played by the OPR in order to ensure the workers’ and others’ safety and, as a consequence, requires a deep knowledge of the forensic-medicine principles. To such purpose, the present paper is aimed to discuss in details the characteristics of the analytical procedures used for opiates, cocaine, cannabis and amfetamine consumption ascertainment, focusing on sensitivity, specificity and accuracy of analytical methods. Moreover the basics of drug metabolization/excretion will be discussed, as well as the possible adulterations of the biological samples and also the more appropriated analysis to be required for a correct data interpretation.

Published
2008

12. Combustion generated nanoparticles: mutagenicity and chemical reactivity

Author

D'ALESSIO, ANTONIO, D'ANNA, ANDREA, SGRO L. A., SIMONELLI A., MIRAGLIA N., ACAMPORA A., SANNOLO N., PASCARELLA L., Simonelli, A, Miraglia, Nadia, Acampora, A, Sannolo, Nicola, Pascarella, L, D'Anna, A, D'Alessio, A, Sgro, La, D'Alessio, Antonio, D'Anna, Andrea, Sgro, L. A., Simonelli, A., Miraglia, N., Acampora, A., Sannolo, N., and Pascarella, L.

Published
2005

13. New biomarkers of exposure [Nuovi indicatori di esposizione]

Author

Apostoli, P., Bergonzi, R., Catalani, S., Neri, G., Sarnico, M., Foà, V., Fustinoni, S., Colombi, A., Buratti, M., Campo, L., Scibetta, L., Sannolo, N., Pieri, M., Basile, A., Bartolucci, G. B., Carrieri, M., Scapellato, M. L., Manini, P., Poli, D., Corradi, M., Andreoli, R., Goldoni, M., Mutti, A., Imbriani, M., Ghittori, S., Maestri, L., Sara Negri, Pira, E., Pavan, I., Discalzi, G., Perbellini, L., Apostoli, P., Bergonzi, R., Catalani, S., Neri, G., Sarnico, M., Foà, V., Fustinoni, S., Colombi, A., Buratti, Marco, Campo, L., Scibetta, L., Sannolo, N., Pieri, M., Basile, A., Bartolucci, G. B., Carrieri, Miriam, Scapellato, M. L., Manini, P., Poli, Diego, Corradi, Antonio, Andreoli, Massimiliano, Goldoni, M., Mutti, A., Imbriani, M., Ghittori, S., Maestri, Alberto, Negri, Lucia, Pira, Francesco, Pavan, Ilaria, Discalzi, G., and Perbellini, L.

Published
2004

14. Linee guida per la sorveglianza sanitaria in agricoltura

Author

Colosio, C., Angotzi, G., Ariano, E., Borghesi, S., Bovenzi, M., Devito, G., Gerardi, D., Gobba, F., L'Abbate, N., Lucchini, R., Maso, S., Mattioli, S., Messineo, A., Miraglia, N., Moretto, A., Musti, M., Occhipinti, E., Peretti, A., Riva, M. A., Romeo, Luciano, Ronchese, F., Rubino, F. M., Saldutti, E., Sannolo, N., Simonelli, A., Somaruga, C., Vellere, F., and Vitelli, N.

Subjects
Agriculture
Published
2013

15. Evaluation by environmental monitoring of pesticide absorption in farm workers of 18 Italian tomato cultivations

Author

Basilicata, P., Simonelli, A., Silvestre, A., Lamberti, M., Paola PEDATA, Feola, D., Acampora, A., Pieri, M., Sannolo, N., Miraglia, N., Basilicata, P., Simonelli, A., Silvestre, A., Lamberti, Monica, Pedata, Paola, Feola, D., Acampora, A., Pieri, M., Sannolo, Nicola, Miraglia, Nadia, Basilicata, Pascale, A., Simonelli, A., Silvestre, M., Lamberti, P., Pedata, D., Feola, A., Acampora, Pieri, Maria, and N., Miraglia

Subjects
pesticides, skin absorption, environmental monitoring, agricultural occupational exposure, tornato cultivation, agricultural occupational exposure, pesticide, skin absorption, tomato cultivation, environmental monitoring
Abstract

Tornato cultivation farms of Soutbern Italy were investigated in order to evaluate tbe generai working conditions and tbe levels of exposure of farm workers to pesticides, during tbe mixinglloading and tbe application of pesticides on fields. Information on working modalities, personal protective equipment, etc. was collected using a questionnaire. Inbaling and cutaneous exposure levels were measured, and tbe estimated pesticide total absorbed dose was compared witb Admissible Daily Intakes (ADIs). Field treatments were mainly carried out by using sprayers witb open cab tractors, and, in 57 ~9% of cases, tbe pesticide mixture was manually prepared by mixing pesticides in a paU, often witbout using gloves (59.5%). Tbe estimated pesticides absorbed doses varied in tbe range 0.56-2630.31 mg (mean value, 46.9 mg), and 20% of tbe measured absorbed doses exceeded ADIs. Tbe findings obtained in tbe 18 examined farms sbow a worrying situation, suggesting tbe investigation of many more farms, so tbat a statistically significant picture of tornato cultivations in Soutbern Italy could be formed. Besides, tbe planning of training courses aimed to increase workers consciousness about bealtb risks and bow tbey can be prevented is advisable.

Published
2013

16. Linee Guida per la Sorveglianza Sanitaria in Agricoltura

Author

Colosio, C, Angotzi, G, Ariano, E, Borghesi, S, Bovenzi, M, De Vito, G, Gerardi, D, Gobba, Fabriziomaria, L'Abbate, N, Lucchini, R, Maso, S, Mattioli, S, Messineo, A, Miraglia, N, Moretto, A, Musti, M, Occhipinti, E, Peretti, A, Riva, Ma, Romeo, L, Ronchese, F, Rubino, Fm, Saldutti, E, Sannolo, N, Simonelli, A, Somaruga, C, Vellere, F, and Vitelli, N.

Subjects
agricoltura, Sorveglianza sanitaria, linee guida
Published
2013

20. Study of the fragmentation pattern of ketamine-heptafluorobutyramide by gas chromatography/electron ionization mass spectrometry

Author

Pieri M, Castiglia L, Miraglia N, Guadagni R, Malorni L, Sannolo N, Acampora A, and Della Casa E

Abstract

Ketamine is an anaesthetic compound used in human and veterinary medicine with hallucinogen properties that have resulted in its increased illicit use by teenagers at rave parties. Although several gas chromatography/mass spectrometry (GC/MS) methods have been reported for the quantification of the drug both in urine and in hair, its electron ionization (EI) fragmentation after derivatization with different reagents has been not yet fully investigated. The present work reports the study of the fragmentation of ketamine, derivatized with heptafluorobutyric anhydride (HFBA-Ket), using gas chromatography/electron ionization mass spectrometry (GC/EI-MS). The complete characterization of the fragmentation pattern represented an intriguing exercise and required tandem mass spectrometry (MS(n)) experiments, high-resolution accurate mass measurements and the use of deuterated d(4)-ketamine to corroborate the proposed structures and to characterize the fragment ions carrying the unchanged aromatic moiety. Extensive fragmentation was observed, mainly located at the cyclohexanone ring followed by rearrangement of the fragment ions, as confirmed by the mass spectra obtained from the deuterated molecule. The GC/EI-MS analysis of HFBA-Ket will represent a useful tool in forensic science since high-throughput analyses are enabled, preserving both the GC stationary phase and the cleanliness of the mass spectrometer ion optics.

Published
2010

28. New biomarkers of exposure

Author

Apostoli, P., Bergonzi, R., Catalani, S., Neri, G., Sarnico, M., Foà, V., Fustinoni, S., Colombi, A., Buratti, M., Campo, L., Scibetta, L., Sannolo, N., Pieri, M., Basile, A., Bartolucci, G. B., Carrieri, M., Scapellato, M. L., Manini, P., Poli, D., Corradi, M., Andreoli, R., Goldoni, M., Mutti, A., Imbriani, M., Ghittori, S., Maestri, L., Negri, S., Pira, Enrico, Pavan, I., Discalzi, G., Perbellini, L., Apostoli, P, Bergonzi, R, Catalani, S, Neri, G, Sarnico, M, Foa, V, Fustinoni, S, Colombi, A, Buratti, M, Campo, L, Scibetta, L, Sannolo, Nicola, Pieri, M, Basile, A, Bartolucci, Gb, Carrieri, M, Scapellato, Ml, Manini, P, Poli, D, Corradi, M, Andreoli, R, Goldoni, M, Mutti, A, Imbriani, M, Ghittori, S, Maestri, L, Negri, S, Pira, E, Pavan, I, Discalzi, G, and Perbellini, L.

Subjects
Cost-Benefit Analysis, Research, Risk Assessment, Sensitivity and Specificity, Rats, Occupational Diseases, biological monitoring, exposure biomarkers, Reference Values, Occupational Exposure, Animals, Humans, risk assessment, occupational health, Occupations, Biomarkers, Occupational Health, Environmental Monitoring, Forecasting
Abstract

In this paper we have defined the new biomarkers of exposure (NBE) as those biomarkers discovered in the last five years and, among previously validated biomarkers, also those applied in different ranges of doses or those determined in biological matrices which differ from matrices originally considered. We examined the results from the surveys carried out by the main Italian research units involved in biological monitoring, i.e. those from the Universities of Brescia, Milan, Naples, Padua, Parma, Pavia, Turin and Verona. The data were collected using a standardized model and included the following: type of element or organic compound, type of biomarker, analytical technique and method, their relationship with environmental monitoring data, their relationship with effect indicators or effects in general, improvement with respect to old biomarkers, reference values. Twenty two NBEs were identified: 14 elements and chemical compounds as such or as metabolites, 4 examples of mixtures, 3 of new matrices, one of speciation. Among the others, aspects such as interest in requiring NBE, quality assurance, availability, cost-benefit ratio were discussed. We conclude that development of this specific field of research appears to be a crucial point for future improvement in risk assessment and health surveillance procedures.

Published
2004

29. Nuovi indicatori di esposizione

Author

Apostoli, P., Bergonzi, R., Catalani, S., Neri, G., Sarnico, M., Foa', V., Fustinoni, S., Colombi, A., Buratti, M., Campo, L., Scibetta, L., Sannolo, N., Pieri, M., Basile, A., Bartolucci, GIOVANNI BATTISTA, Carrieri, Mariella, Scapellato, MARIA LUISA, Manini, P., Poli, D., Corradi, M., Andreoli, R., Goldoni, M., Mutti, A., Imbriani, M., Ghittori, S., Maestri, L., Negri, S., Pira, E., Pavan, I., Discalzi, G., and Perbellini, L.

Published
2004

38. Erythrocyte-mediated toxification of 1,8-dinitropyrene: I. Reduction

Author

Belisario, MARIA ANTONIETTA, Pecce, R., Maturo, M., Avagnale, G., Sannolo, N., Malorni, A., Belisario, Ma, Pecce, R, Maturo, M, Avagnale, G, Sannolo, Nicola, and Malorni, A.

Subjects
Erythrocytes, Pyrenes, Humans, Oxidation-Reduction
Abstract

Nitroarenes are environmental contaminants produced during incomplete combustion processes. It has been reported that nitroreduction, the most important pathway of nitroarene toxification, occurs mainly in the liver and intestine. In the present study we have shown that red cells also possess the metabolic competence to reduce nitroarenes. In particular, 1,8-dinitropyrene, the nitroarene chosen as model compound, was reduced to the corresponding mono- and diamino-derivatives, 1-amino-8-nitropyrene and 1,8-diaminopyrene, by human lysate supplemented with cofactors.

Published
1995

42. Mono‐ and diiodocyclophosphamide as possible internal standards for cyclophosphamide quantification: characterization by ion trap multi‐stage mass spectrometry and effects of iodine‐chlorine substitution on the fragmentation pattern

Author

Castiglia, L., primary, Miraglia, N., additional, Pieri, M., additional, Genovese, G., additional, Simonelli, A., additional, Basilicata, P., additional, Sannolo, N., additional, and Acampora, A., additional

Published
2005
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48. Valutazione delle modifiche funzionali dei neutrofili in lavoratori esposti a xenobiotici.

Author

Garzillo, E. M., Feola, D., Pedata, P., Lamberti, M., Sannolo, N., D'Ancicco, F., and Miraglia., N.

Abstract

Copyright of Giornale Italiano di Medicina del Lavoro ed Ergonomia is the property of Giornale Italiano di Medicina del Lavoro ed Ergonomia Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2012

49. Valutazione in vitro degli effetti cardiotossici da 5-Fluorouracile per la prevenzione dei danni cardiovascolari negli operatori sanitari professionalmente esposti.

Author

Lamberti, M., Caraglia, M., Zappavigna, S., Marra, M., Ritonnaro, C., Coppola, M. A., Naviglio, S., Porto, S., Marsella, L., and Sannolo, N.

Abstract

Copyright of Giornale Italiano di Medicina del Lavoro ed Ergonomia is the property of Giornale Italiano di Medicina del Lavoro ed Ergonomia Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2011

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