7 results on '"Sanmartín-Sánchez, Alicia"'
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2. Renin as a Biomarker to Guide Medical Treatment in Primary Aldosteronism Patients. Findings from the SPAIN-ALDO Registry
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Parra Ramírez, Paola, Martín Rojas-Marcos, Patricia, Paja Fano, Miguel, González-Boillos, Margarita, Pascual-Corrales, Eider, García Cano, Ana María, Ruiz-Sanchez, Jorge Gabriel, Vicente Delgado, Almudena, Gómez Hoyos, Emilia, Ferreira, Rui, García Sanz, Iñigo, Recasens Sala, Mònica, Barahona San Millan, Rebeca, Picón César, María José, Díaz Guardiola, Patricia, Perdomo, Carolina M., Manjón-Miguélez, Laura, Rebollo Román, Ángel, Robles Lázaro, Cristina, Morales-Ruiz, Manuel, Calatayud, María, Andree Furio Collao, Simone, Meneses, Diego, Sampedro-Nuñez, Miguel Antonio, Mena Ribas, Elena, Sanmartín Sánchez, Alicia, Gonzalvo Diaz, Cesar, Lamas, Cristina, Guerrero-Vázquez, Raquel, del Castillo Tous, María, Serrano Gotarredona, Joaquín, Michalopoulou Alevras, Theodora, Tenés Rodrigo, Susana, Roa Chamorro, Ricardo, Jaen Aguila, Fernando, Moya Mateo, Eva María, Hanzu, Felicia A., and Araujo-Castro, Marta
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- 2024
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3. IA-Body Composition CT at T12 in Idiopathic Pulmonary Fibrosis: Diagnosing Sarcopenia and Correlating with Other Morphofunctional Assessment Techniques.
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Fernández-Jiménez, Rocío, Sanmartín-Sánchez, Alicia, Cabrera-César, Eva, Espíldora-Hernández, Francisco, Vegas-Aguilar, Isabel, Amaya-Campos, María del Mar, Palmas-Candia, Fiorella Ximena, Claro-Brandner, María, Olivares-Alcolea, Josefina, Simón-Frapolli, Víctor José, Cornejo-Pareja, Isabel, Guirado-Peláez, Patricia, Vidal-Suárez, Álvaro, Sánchez-García, Ana, Murri, Mora, Garrido-Sánchez, Lourdes, Tinahones, Francisco J., Velasco-Garrido, Jose Luis, and García-Almeida, Jose Manuel
- Abstract
Background: Body composition (BC) techniques, including bioelectrical impedance analysis (BIVA), nutritional ultrasound
® (NU), and computed tomography (CT), can detect nutritional diagnoses such as sarcopenia (Sc). Sc in idiopathic pulmonary fibrosis (IPF) is associated with greater severity and lower survival. Our aim was to explore the correlation of BIVA, NU and functional parameters with BC at T12 level CT scans in patients with IPF but also its relationship with degree of Sc, malnutrition and mortality. Methods: This bicentric cross-sectional study included 60 IPF patients (85.2% male, 70.9 ± 7.8 years). Morphofunctional assessment (MFA) techniques included BIVA, NU, CT at T12 level (T12-CT), handgrip strength, and timed up and go. CT data were obtained using FocusedON® . Statistical analysis was conducted using JAMOVI version 2.3.22 to determine the cutoff points for Sc in T12-CT and to analyze correlations with other MFA techniques. Results: the cutoff for muscle area in T12-CT was ≤77.44 cm2 (area under the curve (AUC) = 0.734, sensitivity = 41.7%, specificity = 100%). The skeletal muscle index (SMI_T12CT) cutoff was ≤24.5 cm2 /m2 (AUC = 0.689, sensitivity = 66.7%, specificity = 66.7%). Low SMI_T12CT exhibited significantly reduced median survival and higher risk of mortality compared to those with normal muscle mass (SMI cut off ≥ 28.8 cm/m2 ). SMI_T12CT was highly correlated with body cell mass from BIVA (r = 0.681) and rectus femoris cross-sectional area (RF-CSA) from NU (r = 0.599). Cronbach's α for muscle parameters across different MFA techniques and CT was 0.735, confirming their validity for evaluating muscle composition. Conclusions: T12-CT scan is a reliable technique for measuring low muscle mass in patients with IPF, specifically when the L3 vertebrae are not captured. An SMI value of <28.8 is a good predictor of low lean mass and 12-month mortality in IPF patients. [ABSTRACT FROM AUTHOR]- Published
- 2024
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4. Differences in the clinical and hormonal presentation of patients with familial and sporadic primary aldosteronism
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Araujo-Castro, Marta, primary, Parra, Paola, additional, Martín Rojas-Marcos, Patricia, additional, Paja Fano, Miguel, additional, González Boillos, Marga, additional, Pascual-Corrales, Eider, additional, García Cano, Ana María, additional, Ruiz-Sanchez, Jorge Gabriel, additional, Vicente Delgado, Almudena, additional, Gómez Hoyos, Emilia, additional, Ferreira, Rui, additional, García Sanz, Iñigo, additional, Recasens Sala, Mònica, additional, Barahona San Millan, Rebeca, additional, Picón César, María José, additional, Díaz Guardiola, Patricia, additional, Perdomo, Carolina M., additional, Manjón-Miguélez, Laura, additional, García Centeno, Rogelio, additional, Rebollo Román, Ángel, additional, Gracia Gimeno, Paola, additional, Robles Lázaro, Cristina, additional, Morales-Ruiz, Manuel, additional, Calatayud, María, additional, Furio Collao, Simone Andree, additional, Meneses, Diego, additional, Sampedro Nuñez, Miguel, additional, Escudero Quesada, Verónica, additional, Mena Ribas, Elena, additional, Sanmartín Sánchez, Alicia, additional, Gonzalvo Diaz, Cesar, additional, Lamas, Cristina, additional, del Castillo Tous, María, additional, Serrano Gotarredona, Joaquín, additional, Michalopoulou Alevras, Theodora, additional, Moya Mateo, Eva María, additional, and Hanzu, Felicia A., additional
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- 2024
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5. Is adrenal venous sampling always necessary to differentiate between unilateral and bilateral primary aldosteronism? Lesson from the SPAIN-ALDO register
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Parra Ramírez, Paola, primary, Martín Rojas-Marcos, Patricia, additional, Paja Fano, Miguel, additional, González Boillos, Marga, additional, Peris, Begoña Pla, additional, Pascual-Corrales, Eider, additional, García Cano, Ana María, additional, Ruiz-Sanchez, Jorge Gabriel, additional, Vicente Delgado, Almudena, additional, Gómez Hoyos, Emilia, additional, Ferreira, Rui, additional, García Sanz, Iñigo, additional, Recasens Sala, Mònica, additional, Barahona San Millan, Rebeca, additional, Picón César, María José, additional, Díaz Guardiola, Patricia, additional, Perdomo, Carolina M., additional, Manjón-Miguélez, Laura, additional, García Centeno, Rogelio, additional, Percovich, Juan Carlos, additional, Rebollo Román, Ángel, additional, Gracia Gimeno, Paola, additional, Robles Lázaro, Cristina, additional, Morales-Ruiz, Manuel, additional, Calatayud, María, additional, Furio Collao, Simone Andree, additional, Meneses, Diego, additional, Sampedro Nuñez, Miguel Antonio, additional, Escudero Quesada, Verónica, additional, Mena Ribas, Elena, additional, Sanmartín Sánchez, Alicia, additional, Gonzalvo Diaz, Cesar, additional, Lamas, Cristina, additional, Guerrero-Vázquez, Raquel, additional, Del Castillo Tous, María, additional, Serrano Gotarredona, Joaquín, additional, Michalopoulou Alevras, Theodora, additional, Moya Mateo, Eva María, additional, Hanzu, Felicia A., additional, and Araujo-Castro, Marta, additional
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- 2023
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6. Autonomous cortisol secretion in patients with primary aldosteronism: prevalence and implications on cardiometabolic profile and on surgical outcomes
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Araujo-Castro, Marta, primary, Paja Fano, Miguel, additional, Pla Peris, Begoña, additional, González Boillos, Marga, additional, Pascual-Corrales, Eider, additional, García-Cano, Ana María, additional, Parra Ramírez, Paola, additional, Rojas-Marcos, Patricia Martín, additional, Ruiz-Sanchez, Jorge Gabriel, additional, Vicente, Almudena, additional, Gómez-Hoyos, Emilia, additional, Ferreira, Rui, additional, García Sanz, Iñigo, additional, Recasens, Mónica, additional, Barahona San Millan, Rebeca, additional, Picón César, María José, additional, Díaz Guardiola, Patricia, additional, Perdomo, Carolina, additional, Manjón, Laura, additional, García-Centeno, Rogelio, additional, Percovich, Juan Carlos, additional, Rebollo Román, Ángel, additional, Gracia Gimeno, Paola, additional, Robles Lázaro, Cristina, additional, Morales, Manuel, additional, Calatayud, María, additional, Collao, Simone Andree Furio, additional, Meneses, Diego, additional, Sampedro Nuñez, Miguel Antonio, additional, Escudero Quesada, Verónica, additional, Ribas, Elena Mena, additional, Sanmartín Sánchez, Alicia, additional, Diaz, Cesar Gonzalvo, additional, Lamas, Cristina, additional, Guerrero-Vázquez, Raquel, additional, del Castillo Tous, María, additional, Serrano, Joaquín, additional, Michalopoulou, Theodora, additional, Moya Mateo, Eva María, additional, and Hanzu, Felicia, additional
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- 2023
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7. Impact of primary aldosteronism on kidney function: results from the SPAIN-ALDO registry.
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Araujo-Castro M, Paja Fano M, González-Boillos M, Pascual-Corrales E, Martín Rojas-Marcos P, García-Cano A, Ruiz-Sanchez JG, Vicente A, Gómez-Hoyos E, Casterás A, Puig-Pérez A, García Sanz I, Recasens M, Barahona San Millan R, Picón César MJ, Díaz Guardiola P, Perdomo CM, Manjón-Miguélez L, Rebollo Román A, Robles Lázaro C, María Recio J, Morales-Ruiz M, Calatayud M, Jiménez López N, Meneses D, Sampedro Nuñez M, Mena Ribas E, Sanmartín Sánchez A, Gonzalvo Diaz C, Lamas C, Castillo Tous MD, Serrano J, Michalopoulou T, Tenés Rodrigo S, Roa Chamorro R, Jaén Aguila F, Moya Mateo EM, Gutiérrez-Medina S, Hanzu FA, and Parra Ramírez P
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- Humans, Female, Male, Middle Aged, Spain epidemiology, Retrospective Studies, Aged, Kidney physiopathology, Renal Insufficiency, Chronic physiopathology, Renal Insufficiency, Chronic complications, Adult, Glomerular Filtration Rate, Cohort Studies, Hyperaldosteronism complications, Hyperaldosteronism physiopathology, Mineralocorticoid Receptor Antagonists therapeutic use, Adrenalectomy, Registries
- Abstract
Aim: To evaluate the impact of aldosterone excess on renal function in individuals with primary aldosteronism and to compare its evolution after surgery or mineralocorticoid receptor antagonist (MRA) treatment., Methods: A multicentre, retrospective cohort study of primary aldosteronism patients in follow-up in 36 Spanish tertiary hospitals, who underwent specific treatment for primary aldosteronism (MRA or adrenalectomy)., Results: A total of 789 patients with primary aldosteronism were included, with a median age of 57.5 years and 41.8% being women. At primary aldosteronism diagnosis, the prevalence of chronic kidney disease (CKD) was 10.7% ( n = 84), with 75% of cases classified as state 3a ( n = 63). Primary aldosteronism patients with CKD had a longer duration of hypertension, a higher prevalence of type 2 diabetes, dyslipidaemia, cardiovascular events, hypokalaemia, and albuminuria. Unilateral adrenalectomy was performed in 41.8% of cases ( n = 330), and 459 patients were treated with MRA. After a median follow-up of 30.7 months (range 13.3-68.4), there was a significant decline in the estimated glomerular filtration rate (eGFR) in operated patients and those receiving MRA. During follow-up, 24.4% of patients with CKD at the time of primary aldosteronism diagnosis had normalized renal function, and 39% of those with albuminuria had albuminuria remission. There were no differences in renal function or albuminuria regression between the two therapy groups. However, development of albuminuria was less common in operated than in medically treated patients (0 vs. 6.0%, P = 0.009)., Conclusion: CKD affects around 10% of the patients with primary aldosteronism, with a higher risk in individuals with long-term hypertension, type 2 diabetes, dyslipidaemia, cardiovascular events, hypokalaemia, and albuminuria. At short-term, both MRA and surgical treatment lead to a reduction of renal function, but adrenalectomy led to higher renal protection., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2024
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- View/download PDF
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