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1. How the First Year of the COVID-19 Pandemic Impacted Patients’ Hospital Admission and Care in the Vascular Surgery Divisions of the Southern Regions of the Italian Peninsula

Author

Martelli, Eugenio, primary, Sotgiu, Giovanni, additional, Saderi, Laura, additional, Federici, Massimo, additional, Sangiorgi, Giuseppe, additional, Zamboni, Matilde, additional, Martelli, Allegra R., additional, Accarino, Giancarlo, additional, Bianco, Giuseppe, additional, Bonanno, Francesco, additional, Bracale, Umberto M., additional, Cappello, Enrico, additional, Cioffi, Giovanni, additional, Colacchio, Giovanni, additional, Crinisio, Adolfo, additional, De Vivo, Salvatore, additional, Dionisi, Carlo Patrizio, additional, Flora, Loris, additional, Impedovo, Giovanni, additional, Intrieri, Francesco, additional, Iorio, Luca, additional, Maritati, Gabriele, additional, Modugno, Piero, additional, Monaco, Mario, additional, Natalicchio, Giuseppe, additional, Palazzo, Vincenzo, additional, Petrosino, Fernando, additional, Pompeo, Francesco, additional, Pulli, Raffaele, additional, Razzano, Davide, additional, Ruggieri, Maurizio R., additional, Ruotolo, Carlo, additional, Sangiuolo, Paolo, additional, Vigliotti, Gennaro, additional, Volpe, Pietro, additional, Biello, Antonella, additional, Boggia, Pietro, additional, Boschetti, Michelangelo, additional, Centritto, Enrico M., additional, Condò, Flavia, additional, Cucciolillo, Lucia, additional, D’Amodio, Amodio S., additional, De Laurentis, Mario, additional, Desantis, Claudio, additional, Di Lella, Daniela, additional, Di Nardo, Giovanni, additional, Disabato, Angelo, additional, Ficarelli, Ilaria, additional, Gasparre, Angelo, additional, Giordano, Antonio N., additional, Luongo, Alessandro, additional, Massara, Mafalda, additional, Molinari, Vincenzo, additional, Padricelli, Andrea, additional, Panagrosso, Marco, additional, Petrone, Anna, additional, Pisanello, Serena, additional, Prunella, Roberto, additional, Tedesco, Michele, additional, and Settembrini, Alberto M., additional

Published
2022
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2. How the First Year of the COVID-19 Pandemic Impacted Patients’ Care in the Vascular Surgery Divisions of the Southern Regions of the Italian Peninsula

Author

Martelli, Eugenio, primary, Sotgiu, Giovanni, additional, Saderi, Laura, additional, Federici, Massimo, additional, Sangiorgi, Giuseppe, additional, Zamboni, Matilde, additional, Martelli, Allegra Rosa, additional, Accarino, Giancarlo, additional, Bianco, Giuseppe, additional, Bonanno, Francesco, additional, Bracale, Umberto Marcello, additional, Cappello, Enrico, additional, Cioffi, Giovanni, additional, Colacchio, Giovanni, additional, Crinisio, Adolfo, additional, De Vivo, Salvatore, additional, Dionisi, Carlo Patrizio, additional, Flora, Loris, additional, Impedovo, Giovanni, additional, Intrieri, Francesco, additional, Iorio, Luca, additional, Maritati, Gabriele, additional, Modugno, Piero, additional, Monaco, Mario, additional, Natalicchio, Giuseppe, additional, Palazzo, Vincenzo, additional, Petrosino, Fernando, additional, Pompeo, Francesco, additional, Pulli, Raffaele, additional, Razzano, Davide, additional, Ruggieri, Maurizio Ruggero, additional, Ruotolo, Carlo, additional, Sangiuolo, Paolo, additional, Vigliotti, Gennaro, additional, Volpe, Pietro, additional, Biello, Antonella, additional, Boggia, Pietro, additional, Boschetti, Michelangelo, additional, Centritto, Enrico Maria, additional, Condò, Flavia, additional, Cucciolillo, Lucia, additional, D'Amodio, Amodio Salvatore, additional, De Laurentis, Mario, additional, Desantis, Claudio, additional, Di Lella, Daniela, additional, Di Nardo, Giovanni, additional, Disabato, Angelo, additional, Ficarelli, Ilaria, additional, Gasparre, Angelo, additional, Giordano, Antonio Nicola, additional, Luongo, Alessandro, additional, Massara, Mafalda, additional, Molinari, Vincenzo, additional, Padricelli, Andrea, additional, Panagrosso, Marco, additional, Petrone, Anna, additional, Pisanello, Serena, additional, Prunella, Roberto, additional, Tedesco, Michele, additional, and Settembrini, Alberto Maria, additional

Published
2022
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4. Increased Activity of the Ubiquitin-Proteasome System in Patients With Symptomatic Carotid Disease Is Associated With Enhanced Inflammation and May Destabilize the Atherosclerotic Plaque: Effects of Rosiglitazone Treatment

Author

Marfella, Raffaele, D’Amico, Michele, Di Filippo, Clara, Baldi, Alfonso, Siniscalchi, Mario, Sasso, Ferndinando Carlo, Portoghese, Michele, Carbonara, Ornella, Crescenzi, Basilio, Sangiuolo, Paolo, Nicoletti, Giovanni Francesco, Rossiello, Raffaele, Ferraraccio, Franca, Cacciapuoti, Federico, Verza, Mario, Coppola, Ludovico, Rossi, Francesco, and Paolisso, Giuseppe

Published
2006
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5. A cross-sectional study evaluating hospitalization rates for chronic limb-threatening ischemia during the COVID-19 outbreak in Campania, Italy

Author

Stabile, Eugenio, primary, Piccolo, Raffaele, additional, Franzese, Michele, additional, Accarino, Giancarlo, additional, Bracale, Umberto Marcello, additional, Cappello, Enrico, additional, Cioffi, Giovanni, additional, Cioppa, Angelo, additional, Crinisio, Adolfo, additional, Flora, Loris, additional, Landino, Pietro, additional, Martelli, Eugenio, additional, Mancusi, Rosario, additional, Niola, Raffaella, additional, Petrosino, Fernando, additional, Razzano, Davide, additional, Ruotolo, Carlo, additional, Salemme, Luigi, additional, Sangiuolo, Paolo, additional, Santini, Gianpaolo, additional, Soreca, Emilio, additional, Vigliotti, Gennaro, additional, Villari, Bruno, additional, Amabile, Giampaolo, additional, Ammollo, Raffaele Pio, additional, Barbarisi, Danilo, additional, Corbisiero, Alfonsina M, additional, D’angelo, Antonio, additional, Cangiano, Gianluca, additional, De Gregorio, Claudia, additional, De Laurentis, Mario, additional, Laurenzano, Eugenio, additional, Ficarelli, Ilaria, additional, Luongo, Alessandro, additional, Molino, Claudio, additional, Sarti, Giuseppe, additional, Viola, Daniela, additional, and Esposito, Giovanni, additional

Published
2020
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7. A cross-sectional study evaluating hospitalization rates for chronic limb-threatening ischemia during the COVID-19 outbreak in Campania, Italy.

Author

Stabile, Eugenio, Piccolo, Raffaele, Franzese, Michele, Accarino, Giancarlo, Bracale, Umberto Marcello, Cappello, Enrico, Cioffi, Giovanni, Cioppa, Angelo, Crinisio, Adolfo, Flora, Loris, Landino, Pietro, Martelli, Eugenio, Mancusi, Rosario, Niola, Raffaella, Petrosino, Fernando, Razzano, Davide, Ruotolo, Carlo, Salemme, Luigi, Sangiuolo, Paolo, and Santini, Gianpaolo

Subjects
COVID-19 pandemic, COVID-19, LEG amputation, CROSS-sectional method, ISCHEMIA
Abstract

The expansion of coronavirus disease 2019 (COVID-19) prompted measures of disease containment by the Italian government with a national lockdown on March 9, 2020. The purpose of this study is to evaluate the rate of hospitalization and mode of in-hospital treatment of patients with chronic limb-threatening ischemia (CLTI) before and during lockdown in the Campania region of Italy. The study population includes all patients with CLTI hospitalized in Campania over a 10-week period: 5 weeks before and 5 weeks during lockdown (n = 453). Patients were treated medically and/or underwent urgent revascularization and/or major amputation of the lower extremities. Mean age was 69.2 ± 10.6 years and 27.6% of the patients were women. During hospitalization, 21.9% of patients were treated medically, 78.1% underwent revascularization, and 17.4% required amputations. In the weeks during the lockdown, a reduced rate of hospitalization for CLTI was observed compared with the weeks before lockdown (25 vs 74/100,000 inhabitants/year; incidence rate ratio: 0.34, 95% CI 0.32–0.37). This effect persisted to the end of the study period. An increased amputation rate in the weeks during lockdown was observed (29.3% vs 13.4%; p < 0.001). This study reports a reduced rate of CLTI-related hospitalization and an increased in-hospital amputation rate during lockdown in Campania. Ensuring appropriate treatment for patients with CLTI should be prioritized, even during disease containment measures due to the COVID-19 pandemic or other similar conditions. [ABSTRACT FROM AUTHOR]

Published
2021
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8. Morning Blood Pressure Surge as a Destabilizing Factor of Atherosclerotic Plaque

Author

Marfella, Raffaele, primary, Siniscalchi, Mario, additional, Portoghese, Michele, additional, Di Filippo, Clara, additional, Ferraraccio, Franca, additional, Schiattarella, Concetta, additional, Crescenzi, Basilio, additional, Sangiuolo, Paolo, additional, Ferraro, Giuseppe, additional, Siciliano, Silvio, additional, Cinone, Francesca, additional, Mazzarella, Gennaro, additional, Martis, Simone, additional, Verza, Mario, additional, Coppola, Ludovico, additional, Rossi, Francesco, additional, D’Amico, Michele, additional, and Paolisso, Giuseppe, additional

Published
2007
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9. Percutaneous Splenic Artery Occlusion for Portal Hypertension: A New Mechanical Technique for Hypersplenism

Author

Zannini, Giuseppe, Masciariello, Stefano, Pagano, Giorgio, Sangiuolo, Paolo, Zotti, Giancarlo, and Iaccarino, Vittorio

Abstract

• We studied 16 patients with hypersplenism, splenomegaly, and moderate nonbleeding portal hypertension with the purpose of discovering a hyperdynamic component associated with splenomegaly. We treated the patients' splenic hyperdynamic component and hypersplenism with a splenectomy. We measured wedge hepatic vein pressure (WHVP) before and after superior mesenteric artery occlusion by a balloon catheter, and after splenic artery (SA) occlusion by a balloon catheter. In 11 patients, following SA temporary occlusion an average WHVP reduction of 10.4 cm saline was obtained, and SA occlusion by Gianturco's coils was performed to obtain a gradual and segmentary occlusion. No colliquative phenomena were observed, and a stable decrease of WHVP with a marked improvement of peripheral cytopenia was obtained.(Arch Surg 1983;118:897-900)

Published
1983
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11. How the First Year of the COVID-19 Pandemic Impacted Patients' Hospital Admission and Care in the Vascular Surgery Divisions of the Southern Regions of the Italian Peninsula

Author

Eugenio Martelli, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe Sangiorgi, Matilde Zamboni, Allegra R. Martelli, Giancarlo Accarino, Giuseppe Bianco, Francesco Bonanno, Umberto M. Bracale, Enrico Cappello, Giovanni Cioffi, Giovanni Colacchio, Adolfo Crinisio, Salvatore De Vivo, Carlo Patrizio Dionisi, Loris Flora, Giovanni Impedovo, Francesco Intrieri, Luca Iorio, Gabriele Maritati, Piero Modugno, Mario Monaco, Giuseppe Natalicchio, Vincenzo Palazzo, Fernando Petrosino, Francesco Pompeo, Raffaele Pulli, Davide Razzano, Maurizio R. Ruggieri, Carlo Ruotolo, Paolo Sangiuolo, Gennaro Vigliotti, Pietro Volpe, Antonella Biello, Pietro Boggia, Michelangelo Boschetti, Enrico M. Centritto, Flavia Condò, Lucia Cucciolillo, Amodio S. D’Amodio, Mario De Laurentis, Claudio Desantis, Daniela Di Lella, Giovanni Di Nardo, Angelo Disabato, Ilaria Ficarelli, Angelo Gasparre, Antonio N. Giordano, Alessandro Luongo, Mafalda Massara, Vincenzo Molinari, Andrea Padricelli, Marco Panagrosso, Anna Petrone, Serena Pisanello, Roberto Prunella, Michele Tedesco, Alberto M. Settembrini, Martelli, Eugenio, Sotgiu, Giovanni, Saderi, Laura, Federici, Massimo, Sangiorgi, Giuseppe, Zamboni, Matilde, Martelli, Allegra R., Accarino, Giancarlo, Bianco, Giuseppe, Bonanno, Francesco, Bracale, Umberto M., Cappello, Enrico, Cioffi, Giovanni, Colacchio, Giovanni, Crinisio, Adolfo, De Vivo, Salvatore, Dionisi, Carlo Patrizio, Flora, Lori, Impedovo, Giovanni, Intrieri, Francesco, Iorio, Luca, Maritati, Gabriele, Modugno, Piero, Monaco, Mario, Natalicchio, Giuseppe, Palazzo, Vincenzo, Petrosino, Fernando, Pompeo, Francesco, Pulli, Raffaele, Razzano, Davide, Ruggieri, Maurizio R., Ruotolo, Carlo, Sangiuolo, Paolo, Vigliotti, Gennaro, Volpe, Pietro, Biello, Antonella, Boggia, Pietro, Boschetti, Michelangelo, Centritto, Enrico M., Condò, Flavia, Cucciolillo, Lucia, D’Amodio, Amodio S., De Laurentis, Mario, Desantis, Claudio, Di Lella, Daniela, Di Nardo, Giovanni, Disabato, Angelo, Ficarelli, Ilaria, Gasparre, Angelo, Giordano, Antonio N., Luongo, Alessandro, Massara, Mafalda, Molinari, Vincenzo, Padricelli, Andrea, Panagrosso, Marco, Petrone, Anna, Pisanello, Serena, Prunella, Roberto, Tedesco, Michele, and Settembrini, Alberto M.

Subjects
carotid stenosi, chronic limb-threatening ischemia, abdominal aortic aneurysm, amputation, Medicine (miscellaneous), COVID-19, carotid stenosis, deep venous thrombosis, Settore MED/09
Abstract

Background: To investigate the effects of the COVID-19 lockdowns on the vasculopathic population. Methods: The Divisions of Vascular Surgery of the southern Italian peninsula joined this multicenter retrospective study. Each received a 13-point questionnaire investigating the hospitalization rate of vascular patients in the first 11 months of the COVID-19 pandemic and in the preceding 11 months. Results: 27 out of 29 Centers were enrolled. April-December 2020 (7092 patients) vs. 2019 (9161 patients): post-EVAR surveillance, hospitalization for Rutherford category 3 peripheral arterial disease, and asymptomatic carotid stenosis revascularization significantly decreased (1484 (16.2%) vs. 1014 (14.3%), p = 0.0009; 1401 (15.29%) vs. 959 (13.52%), p = 0.0006; and 1558 (17.01%) vs. 934 (13.17%), p < 0.0001, respectively), while admissions for revascularization or major amputations for chronic limb-threatening ischemia and urgent revascularization for symptomatic carotid stenosis significantly increased (1204 (16.98%) vs. 1245 (13.59%), p < 0.0001; 355 (5.01%) vs. 358 (3.91%), p = 0.0007; and 153 (2.16%) vs. 140 (1.53%), p = 0.0009, respectively). Conclusions: The suspension of elective procedures during the COVID-19 pandemic caused a significant reduction in post-EVAR surveillance, and in the hospitalization of asymptomatic carotid stenosis revascularization and Rutherford 3 peripheral arterial disease. Consequentially, we observed a significant increase in admissions for urgent revascularization for symptomatic carotid stenosis, as well as for revascularization or major amputations for chronic limb-threatening ischemia.

Published
2022

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