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Abstract Visual surveillance systems have been playing an important role in monitoring and managing at public areas. However, the computational complexity of video compression in these applications is still a great challenge. To meet practical requirements, the authors propose in this paper a low‐complexity surveillance video coding solution in which the most recent Versatile Video Coding (VVC) standard is improved with a novel learning adaptive motion search algorithm. The proposed algorithm is designed based on the temporal motion and spatial texture characteristics of surveillance videos. First, the authors study and define a list of spatial and temporal features which indicates the motion and texture characteristics of surveillance video. These features are used together with a machine learning algorithm to appropriately assign a search range for the VVC motion search. Second, to reduce search points, the authors propose an adaptive Test Zone (TZ) search in which TZ steps are early terminated following the variation of spatial–temporal features. Performance evaluation conducted for a rich set of surveillance videos and relevant benchmarks have shown the superiority of the proposed method, notably with around 33% of encoding time saving when compared with the state‐of‐the art VVC solution and relevant benchmarks while asking for negligible compression loss.

The design of commercial supercapacitors has remained largely unchanged since the 1970s, comprising powdered electrodes housed in rigid metal cylinders or pouches. To power the next generation of integrated technologies, an evolution in supercapacitor materials and design is needed to create multifunctional materials that allow energy storage while imparting additional material properties (e.g., flexibility and strength). Conductive free-standing electrodes produced from fibers or 3D printed materials offer this opportunity as their intrinsic mechanical properties can be transferred to the supercapacitor. Additionally, their conductive nature allows for the removal of binders, conductive agents, and current collectors from the supercapacitor devices, lowering their economic and environmental cost. In this Perspective, we summarize the recent progress on free-standing supercapacitors from new methods to create free-standing electrodes to novel applications for these devices, together with a detailed discussion and analysis on their electrochemical performance and physicochemical and mechanical properties. Furthermore, the potential directions and prospects of future research in developing free-standing supercapacitors are proposed.

Type 1 Natural Killer T-cells (NKT1 cells) play a critical role in mediating hepatic ischemia-reperfusion injury (IRI). Although hepatic steatosis is a major risk factor for preservation type injury, how NKT cells impact this is understudied. Given NKT1 cell activation by phospholipid ligands recognized presented by CD1d, we hypothesized that NKT1 cells are key modulators of hepatic IRI because of the increased frequency of activating ligands in the setting of hepatic steatosis. We first demonstrate that IRI is exacerbated by a high-fat diet (HFD) in experimental murine models of warm partial ischemia. This is evident in the evaluation of ALT levels and Phasor-Fluorescence Lifetime (Phasor-FLIM) Imaging for glycolytic stress. Polychromatic flow cytometry identified pronounced increases in CD45+CD3+NK1.1+NKT1 cells in HFD fed mice when compared to mice fed a normal diet (ND). This observation is further extended to IRI, measuring ex vivo cytokine expression in the HFD and ND. Much higher interferon-gamma (IFN-γ) expression is noted in the HFD mice after IRI. We further tested our hypothesis by performing a lipidomic analysis of hepatic tissue and compared this to Phasor-FLIM imaging using “long lifetime species”, a byproduct of lipid oxidation. There are higher levels of triacylglycerols and phospholipids in HFD mice. Since N-acetylcysteine (NAC) is able to limit hepatic steatosis, we tested how oral NAC supplementation in HFD mice impacted IRI. Interestingly, oral NAC supplementation in HFD mice results in improved hepatic enhancement using contrast-enhanced magnetic resonance imaging (MRI) compared to HFD control mice and normalization of glycolysis demonstrated by Phasor-FLIM imaging. This correlated with improved biochemical serum levels and a decrease in IFN-γ expression at a tissue level and from CD45+CD3+CD1d+ cells. Lipidomic evaluation of tissue in the HFD+NAC mice demonstrated a drastic decrease in triacylglycerol, suggesting downregulation of the PPAR-γ pathway.

The research analyses the impact of non-interest income on the performance of 26 Vietnamese commercial banks in the period of 2008 - 2017 by the Generalized Method of Moments (GMM) method. The research results show that: (i) The average non-interest income ratio of Vietnamese commercial banks is only 8.32%, a significantly low level compared with the interest income ratio of more than 90% of the total income of the banks; (ii) Non-interest income has a positive impact on the performance of Vietnamese commercial banks in the research period. The research results assist in confirming the trend of diversifying non-credit activities to increase non-interest income ratio of Vietnamese commercial banks.

This study investigates the impact of market power on bank financial stability using bank-level data from 24 banks in Vietnam over the 2008-2017 period. In order to measure the degree of market power in the Vietnam banking sector, we compute the separated Lerner index by fixed effect model, random effect model, and Z-score as a measure of financial stability. We use the static and dynamic panel data regression methods to esti-mate the relationship between market power and financial stability. Our results support the “competition - sta-bility” view and show that Vietnamese commercial banks facing little competition tended to be less stable. We also find that size had a positive effect on stability while loan growth rate had a negative effect on financial stability. The study suggests some important policy implications for improving bank stability in Vietnam.

Abstract Hypothermia might be an adverse effect of Amoxicillin and/or Sulbactam, and clinicians should be aware of this effect. Further clinical and laboratory investigations are also needed to confirm and clarify the underlying mechanism of this side effect.

Despite high remission rates following CAR-T cell therapy in B-ALL, relapse due to loss of the targeted antigen is increasingly recognized as a mechanism of immune escape. We hypothesized that simultaneous targeting of CD19 and CD22 may reduce the likelihood of antigen loss, thus improving sustained remission rates. A systematic approach to the generation of CAR constructs incorporating two target-binding domains led to several novel CD19/CD22 bivalent CAR constructs. Importantly, we demonstrate the challenges associated with the construction of a bivalent CAR format that preserves bifunctionality against both CD19 and CD22. Using the most active bivalent CAR constructs, we found similar transduction efficiency compared to that of either CD19 or CD22 single CARs alone. When expressed on human T cells, the optimized CD19/CD22 CAR construct induced comparable interferon γ and interleukin-2 in vitro compared to single CARs against dual-antigen-expressing as well as single-antigen-expressing cell lines. Finally, the T cells expressing CD19/CD22 CAR eradicated ALL cell line xenografts and patient-derived xenografts (PDX), including a PDX generated from a patient with CD19− relapse following CD19-directed CAR therapy. The CD19/CD22 bivalent CAR provides an opportunity to test whether simultaneous targeting may reduce risk of antigen loss. Keywords: chimeric antigen receptor, adoptive cell therapy, leukemia

In this paper, we study the secure communication of cognitive energy harvesting relay networks when there exist multiple eaves droppers who can overhear the message of the second hop, and multiple primary users are present. The data transmission from the secondary source to the secondary destination is assisted by the best decode-and-forward relay, which is selected by means of three relay selection schemes. We study the system security performance by deriving the exact analytical secrecy outage probability. These analytical expressions are then verified by comparison to the results of Monte Carlo simulations. Herein we evaluate and discuss the outage performance of the three schemes under variations in important system parameters: the number and locations of relay nodes, primary user nodes, and eavesdroppers; the transmit power threshold; the energy harvesting efficiency coefficient; the power splitting ratio; and the target secure rate.

Background Diabetic ketoacidosis (DKA), a critical and potentially fatal complication resulting from a lack of insulin, presents with elevated blood sugar, acid-base imbalance, and increased ketone bodies. Objectives Our research was designed to assess the clinical manifestations, laboratory findings, and outcomes of treatment in children diagnosed with DKA over a span of five years in the Mekong Delta region of Vietnam. Methods This study retrospectively analyzed pediatric cases of diabetic ketoacidosis treated at a major pediatric center in the Mekong Delta between 2017 and 2021. Results Diabetic ketoacidosis was more common in older children aged 11 - 16 years (66.7%), and females (70%). The majority of cases had not been diagnosed with previous diabetes (60%) and no history of diabetic ketoacidosis (90%). In univariate analysis, female gender (OR, 13.0; 95% CI, 1.4 - 124.3; p=0.026), previous diabetes diagnosis (OR, 7.8; 95% CI, 1.5 - 41.2; p=0.016), precipitating factors (OR, 10.1; 95% CI, 1.1 - 97.0; p=0.045), tachypnea (OR, 5.5; 95% CI, 1.1 - 26.4; p=0.033), Kussmaul breathing (OR, 5.4; 95% CI, 1.1 - 26.0; p=0.036), serum potassium level (OR, 3.5; 95% CI, 1.2 - 10.4; p=0.027), and anion gap (OR, 1.6; 95% CI, 1.8 - 2.3; p=0.003) were associated factors with severe DKA. All cases in our study had a 100% survival rate. Anion gap was an independent factor associated with severe diabetic ketoacidosis after adjustment multivariate analysis. Conclusion: Female, younger age, precipitating factors, tachypnea, Kussmaul's breathing, and relevant laboratory findings, including increased anion gap, should be considered to ensure successful management in pediatric diabetic ketoacidosis. [ABSTRACT FROM AUTHOR]