Search

Your search keyword '"Sang, Hongfei"' showing total 240 results
Start Over Author "Sang, Hongfei"
240 results on '"Sang, Hongfei"'

1. Mechanical Thrombectomy for Large Ischemic Stroke: A Systematic Review and Meta-analysis.

Author

Li, Qi, Abdalkader, Mohamad, Siegler, James, Yaghi, Shadi, Sarraj, Amrou, Campbell, Bruce, Yoo, Albert, Zaidat, Osama, Kaesmacher, Johannes, Pujara, Deep, Nogueira, Raul, Saver, Jeffrey, Li, Lei, Han, Qin, Dai, Yi, Sang, Hongfei, Yang, Qingwu, Nguyen, Thanh, and Qiu, Zhongming

Subjects
Humans, Stroke, Brain Ischemia, Endovascular Procedures, Thrombectomy, Ischemic Stroke, Treatment Outcome, Randomized Controlled Trials as Topic, Observational Studies as Topic
Abstract

BACKGROUND AND OBJECTIVES: There is growing evidence for endovascular thrombectomy (EVT) in patients with large ischemic core infarct and large vessel occlusion (LVO). The objective of this study was to compare the efficacy and safety of EVT vs medical management (MM) using a systematic review and meta-analysis of observational studies and randomized controlled trials (RCTs). METHODS: We searched the PubMed, Embase, Cochrane Library, and Web of Science databases to obtain articles related to mechanical thrombectomy for large ischemic core from inception until February 10, 2023. The primary outcome was independent ambulation (modified Rankin Scale [mRS] 0-3). Effect sizes were computed as risk ratio (RR) with random-effect or fixed-effect models. The quality of articles was evaluated through the Cochrane risk assessment tool and the Newcastle-Ottawa Scale. This study was registered in PROSPERO (CRD42023396232). RESULTS: A total of 5,395 articles were obtained through the search and articles that did not meet the inclusion criteria were excluded by review of the title, abstract, and full text. Finally, 3 RCTs and 10 cohort studies met the inclusion criteria. The RCT analysis showed that EVT improved the 90-day functional outcomes of patients with large ischemic core with high-quality evidence, including independent ambulation (mRS 0-3: RR 1.78, 95% CI 1.28-2.48, p < 0.001) and functional independence (mRS 0-2: RR 2.59, 95% CI 1.89-3.57, p < 0.001), but without significantly increasing the risk of symptomatic intracranial hemorrhage (sICH: RR 1.83, 95% CI 0.95-3.55, p = 0.07) or early mortality (RR 0.95, 95% CI 0.78-1.16, p = 0.61). Analysis of the cohort studies showed that EVT improved functional outcomes of patients without an increase in the incidence in sICH. DISCUSSION: This systematic review and meta-analysis indicates that in patients with LVO stroke with a large ischemic core, EVT was associated with improved functional outcomes over MM without increasing sICH risk. The results of ongoing RCTs may provide further insight in this patient population.

Published
2023

2. Association of Tirofiban With Functional Outcomes After Thrombectomy in Acute Ischemic Stroke Due to Intracranial Atherosclerotic Disease.

Author

Nogueira, Raul, Wu, Junxiong, Long, Chen, Tian, Zhenxuan, Hu, Zhizhou, Wang, Tao, Li, Rongzong, Ke, Yingbing, Zhu, Xiurong, Peng, Daizhou, Chang, Mingze, Li, Lingfei, Ruan, Jie, Wu, Deping, Zi, Wenjie, Yang, Qingwu, Li, Fengli, Qiu, Zhongming, Sang, Hongfei, Xie, Dongjing, Tian, Yan, Nguyen, Thanh, and Saver, Jeffrey

Subjects
Male, Humans, Middle Aged, Aged, Female, Tirofiban, Stroke, Ischemic Stroke, Treatment Outcome, Thrombectomy, Intracranial Arteriosclerosis, Endovascular Procedures, Brain Ischemia
Abstract

BACKGROUND AND OBJECTIVE: To investigate the efficacy and safety of IV infusion of tirofiban before endovascular thrombectomy for patients with large vessel occlusion due to intracranial atherosclerotic disease. The secondary objective was to identify potential mediators for the clinical effect of tirofiban. METHODS: Post hoc exploratory analysis of the Endovascular Treatment With versus Without Tirofiban for Patients with Large Vessel Occlusion Stroke (RESCUE BT) trial, which was a randomized, double-blinded, placebo-controlled trial at 55 centers in China from October 2018 to October 2021. Patients with occlusion of the internal carotid artery or middle cerebral artery due to intracranial atherosclerosis were included. The primary efficacy outcome was the proportion of patients achieving functional independence (defined as modified Rankin scale 0-2) at 90 days. Binary logistic regression and causal mediation analyses were used to estimate the treatment effect of tirofiban and the potential mediators. RESULTS: This study included 435 patients, of whom 71.5% were men. The median age was 65 (interquartile range [IQR] 56-72) years, with a median NIH Stroke Scale of 14 (IQR 10-19). Patients in the tirofiban group had higher rates of functional independence at 90 days than patients in the placebo group (adjusted odds ratio 1.68; 95% CI 1.11-2.56, p = 0.02) without an increased risk of mortality or symptomatic intracranial hemorrhage. Tirofiban was associated with fewer thrombectomy passes (median [IQR] 1 [1-2] vs 1 [1-2], p = 0.004), which was an independent predictor of functional independence. Mediation analysis showed tirofiban-reduced thrombectomy passes explained 20.0% (95% CI 4.1%-76.0%) of the effect of tirofiban on functional independence. DISCUSSION: In this post hoc analysis of the RESCUE BT trial, tirofiban was an effective and well-tolerated adjuvant medication of endovascular thrombectomy for patients with large vessel occlusion due to intracranial atherosclerosis. These findings need to be confirmed in future trials. TRIAL REGISTRATION INFORMATION: The RESCUE BT trial was registered on the Chinese Clinical Trial Registry: chictr.org.cn, ChiCTR-INR-17014167. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that tirofiban plus endovascular therapy improves 90-day outcome for patients with large vessel occlusion due to intracranial atherosclerosis.

Published
2023

4. Specialist Perspectives on the Imaging Selection of Large Vessel Occlusion in the Late Window

Author

Klein, Piers, Huo, Xiaochuan, Chen, Yimin, Abdalkader, Mohamad, Qiu, Zhongming, Nagel, Simon, Raymond, Jean, Liu, Liping, Siegler, James E., Strbian, Daniel, Field, Thalia S., Yaghi, Shadi, Qureshi, Muhammad M., Demeestere, Jelle, Puetz, Volker, Berberich, Anne, Michel, Patrik, Fischer, Urs, Kaesmacher, Johannes, Yamagami, Hiroshi, Alemseged, Fana, Tsivgoulis, Georgios, Schonewille, Wouter J., Hu, Wei, Liu, Xinfeng, Li, Chuanhui, Ji, Xunming, Drumm, Brian, Banerjee, Soma, Sacco, Simona, Sandset, Else C., Kristoffersen, Espen Saxhaug, Slade, Peter, Mikulik, Robert, Romoli, Michele, Diana, Francesco, Krishnan, Kailash, Dhillon, Permesh, Lee, Jin Soo, Kasper, Ekkehard, Dasenbrock, Hormuzdiyar, Ton, Mai Duy, Masiliūnas, Rytis, Arsovska, Anita Ante, Marto, João Pedro, Dmytriw, Adam A., Regenhardt, Robert W., Silva, Gisele Sampaio, Siepmann, Timo, Sun, Dapeng, Sang, Hongfei, Diestro, Jose Danilo, Yang, Pengfei, Mohammaden, Mahmoud H., Li, Fengli, Masoud, Hesham E., Ma, Alice, Raynald, Ganesh, Aravind, Liu, Jianmin, Meyer, Lukas, Dippel, Diederik W. J., Thomalla, Götz, Parsons, Mark, Qureshi, Adnan I., Goyal, Mayank, Yoo, Albert J., Lapergue, Bertrand, Zaidat, Osama O., Chen, Hui-Sheng, Campbell, Bruce C. V., Jovin, Tudor G., Nogueira, Raul G., Miao, Zhongrong, Saposnik, Gustavo, and Nguyen, Thanh N.

Published
2023
Full Text
View/download PDF

6. Intravenous Tirofiban Versus Alteplase Before Endovascular Treatment in Acute Ischemic Stroke: A Pooled Analysis of the DEVT and RESCUE BT Trials

Author

Sang, Hongfei, Cao, Zhihua, Du, Jie, Nguyen, Thanh N., Saver, Jeffrey L., Mao, An, Nogueira, Raul G., Tao, Zhaojun, Zhou, Simin, Han, Qin, Sun, Dong, Lei, Bo, Liu, Shudong, Zeng, Guoyong, Yin, Congguo, Xie, Dongjing, Luo, Weidong, Jin, Zhenglong, Qiu, Zhongming, Yang, Qingwu, Wu, Deping, Shi, Zhonghua, Huang, Wenguo, Liu, Wenhua, Qiu, Tao, Zhou, Peiyang, Wang, Li, Fu, Xinmin, Yang, Shiquan, Zhang, Shuai, Zhou, Zhiming, Wang, Yan, Luo, Jun, Bai, Yongjie, Zhang, Min, Wu, Youlin, Wan, Yue, Wen, Changming, Wen, Hongbin, Ling, Wentong, Chen, Zhuo., Peng, Miao, Ai, Zhibing, Guo, Fuqiang, Guo, Jing, Guan, Haitao, Wang, Zhiyi, Liu, Yong, Pu, Jie, Wang, Zhen, Yang, Qingwu, Liu, Wenhua, Li, Huagang, Huang, Wenguo, Zhang, Min, Zhou, Peiyang, Zhou, Zhiming, Song, Bo, Wen, Changming, Yuan, Guangxiong, Luo, Jun, Zheng, Chong, Wang, Shouchun, Wang, Tao, Qi, Li, Wan, Yue, Wu, Youlin, Peng, Daizhou, Chang, Mingze, Shi, Zhonghua, Jin, Ying, Huang, Chuming, Liu, Tianzhu, Zhao, Wenlong, Wang, Jian, Wang, Li, Liu, Shugai, Luo, Shiwei, Pu, Jie, Chen, Shengli, Sun, Yaxuan, Jiang, Shunfu, Wei, Liping, Fu, Xinmin, Bai, Yongjie, Yang, Shunyu, Hu, Wei, Zhang, Guling, Pan, Chengde, Zhang, Shuai, Wang, Yan, Cao, Wenfeng, Yang, Shiquan, Zhang, Jun, Guo, Fuqiang, Wen, Hongbin, Zhang, Jinhua, and Lu, Mengjie

Published
2024
Full Text
View/download PDF

9. Association between intravenous tirofiban and intracranial hemorrhage in acute large vessel occlusion stroke: insight from the RESCUE BT randomized placebo-controlled trial

Author

Sang, Hongfei, Huang, Jiacheng, Jiang, Bingwu, Guo, Qifeng, Nguyen, Thanh N., Abdalkader, Mohamad, Han, Qin, Zhou, Simin, Tao, Zhaojun, Mao, An, Yan, Zhizhong, Du, Jie, Jin, Ying, Huang, Chuming, Liu, Tianzhu, Zhao, Wenlong, Gu, Gangfeng, Wang, Li, Liu, Shugai, Luo, Shiwei, Pu, Jie, Hu, Jinrong, Yang, Jie, Li, Fengli, Zi, Wenjie, Hu, Xiaogang, and Qiu, Zhongming

Published
2023
Full Text
View/download PDF

11. Effect of Imaging Selection Paradigms on Endovascular Thrombectomy Outcomes in Patients With Acute Ischemic Stroke

Author

Miao, Jian, Sang, Hongfei, Li, Fengli, Saver, Jeffrey L., Lei, Bo, Li, Jinglun, Nogueira, Raul Gomes, Song, Bo, Liu, Shudong, Nguyen, Thanh N., Jin, Zhenglong, Zeng, Hongliang, Wen, Changming, Yuan, Guangxiong, Kong, Weilin, Luo, Weidong, Liu, Shuai, Xie, Dongjing, Huang, Jiacheng, Liu, Chang, Yang, Jie, Hu, Jinrong, Song, Jiaxing, Yue, Chengsong, Li, Linyu, Tian, Yan, Zhang, Xiao, Feng, Dan, Gao, Yani, Fu, Huiying, Zi, Wenjie, Yang, Qingwu, Qiu, Zhongming, and Wang, Shaojun

Published
2023
Full Text
View/download PDF

12. Protocol of the Reformation study: a prospective, multicenter, randomized controlled trial on the improvement of rheolytic thrombectomy for acute deep vein thrombosis of the whole lower limb by primary popliteal vein thrombosis clearance

Author

Ni, Qihong, primary, Ye, Xiande, additional, He, Chunshui, additional, Zhao, Hui, additional, Lou, Wensheng, additional, Zhuang, Hui, additional, Sang, Hongfei, additional, Wu, Ziheng, additional, and Ye, Meng, additional

Published
2024
Full Text
View/download PDF

13. Correction to: Outcomes of Endovascular Therapy in Young Patients with Acute Basilar Artery Occlusion: A Substudy of BASILAR Registry Study

Author

Hu, Jinrong, Liu, Xing, Liu, Shuai, Sang, Hongfei, Huang, Jiacheng, Luo, Weidong, Wang, Jie, Chen, Zhuo, Yang, Shuang, He, Wencheng, Zhang, Bo, Yu, Zhou, Wang, Shan, Wen, Hongbin, Zhu, Xiurong, Sun, Ruidi, Yang, Jie, Li, Linyu, Song, Jiaxing, Tian, Yan, Qiu, Zhongming, Li, Fengli, Zi, Wenjie, Tian, Yaoyu, and Yang, De

Published
2022
Full Text
View/download PDF

15. Early outcomes of drug-coated balloon angioplasty of infrapopliteal lesions in diabetic foot

Author

Guo, Julong, primary, Ye, Meng, additional, Zhang, Wei, additional, Wu, Ziheng, additional, Feng, Zibo, additional, Fang, Xin, additional, Li, Qiang, additional, Sang, Hongfei, additional, Shi, Zhenyu, additional, Shi, Weihao, additional, He, Chunshui, additional, Gao, Xixiang, additional, Guo, Jianming, additional, Tong, Zhu, additional, and Guo, Lianrui, additional

Published
2024
Full Text
View/download PDF

16. Effects of tirofiban on large vessel occlusion stroke are modified by etiology and renal function.

Author

Liu, Chang, Li, Fengli, Chen, Liyuan, Huang, Jiacheng, Sang, Hongfei, Nguyen, Thanh N., Saver, Jeffrey L., Abdalkader, Mohamad, Kong, Weiling, Yang, Jie, Guo, Changwei, Gong, Chen, Huang, Liping, Pan, Yanzhu, Wang, Xinxin, Chen, Yangmei, Qiu, Zhongming, and Zi, Wenjie

Subjects
KIDNEY physiology, TIROFIBAN, STROKE patients, INTRACRANIAL hemorrhage, GLOMERULAR filtration rate
Abstract

Objective: Renal function can modify the outcomes of large vessel occlusion (LVO) stroke across stroke etiologies in disparate degrees. The presence of renal function deficit can also impair the pharmacokinetics of tirofiban. Hence, this study aimed to investigate the roles of renal function in determining efficacy and safety of intravenous tirofiban before endovascular treatment (EVT) for acute ischemic stroke patients with large vessel occlusion (LVO). Methods: This study was a post hoc exploratory analysis of the RESCUE‐BT trial. The primary outcome was the proportion of patients achieving functional independence (modified Rankin scale 0–2) at 90 days, and the primary safety outcome was the rate of symptomatic intracranial hemorrhage (sICH). Results: Among 908 individuals with available serum creatinine, decreased estimated glomerular filtration rate (eGFR) status was noted more commonly in patients with cardioembolic stroke (CE), while large artery atherosclerosis (LAA) was predominant in patients with normal renal function. In LAA with normal renal function, tirofiban was associated with higher rates of functional independence at 90 days (41.67% vs 59.80%, p = 0.003). However, for LVO patients with renal dysfunction, tirofiban did not improve functional outcomes for any of the etiologies (LAA, p = 0.876; CE, p = 0.662; others, p = 0.894) and significantly increased the risk of sICH among non‐LAA patients (p = 0.020). Mediation analysis showed tirofiban reduced thrombectomy passes (12.27%) and drug/placebo to recanalization time (14.25%) mediated its effects on functional independence. Conclusion: This present study demonstrated the importance of evaluating renal function before administering intravenous tirofiban among patients with LVO who are planned to undergo EVT. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

18. Association of Tirofiban With Functional Outcomes After Thrombectomy in Acute Ischemic Stroke Due to Intracranial Atherosclerotic Disease

Author

Sang, Hongfei, primary, Xie, Dongjing, additional, Tian, Yan, additional, Nguyen, Thanh N., additional, Saver, Jeffrey L., additional, Nogueira, Raul G, additional, Wu, Junxiong, additional, Long, Chen, additional, Tian, Zhenxuan, additional, Hu, Zhizhou, additional, Wang, Tao, additional, Li, Rongzong, additional, Ke, Yingbing, additional, Zhu, Xiurong, additional, Peng, Daizhou, additional, Chang, Mingze, additional, Li, Lingfei, additional, Ruan, Jie, additional, Wu, Deping, additional, Zi, Wenjie, additional, Yang, Qingwu, additional, Li, Fengli, additional, and Qiu, Zhongming, additional

Published
2023
Full Text
View/download PDF

19. Systemic THrombolysis Randomization IN Endovascular Stroke Therapy (SHRINE) Collaboration: a patient-level pooled analysis of the SKIP and DEVT Trials

Author

Nogueira, Raul G, Kimura, Kazumi, Matsumaru, Yuji, Suzuki, Kentaro, Qiu, Zhongming, Zi, Wenjie, Moran, Timothy P, Li, Fengli, Sang, Hongfei, Luo, Weidong, Liu, Shuai, Yuan, Junjie, Song, Jiaxing, Huang, Jiacheng, Takeuchi, Masataka, Morimoto, Masafumi, Otsuka, Toshiaki, and Yang, Qingwu

Abstract

ObjectiveTo evaluate the non-inferiority of endovascular treatment (EVT) alone versus intravenous thrombolysis (IVT) followed by EVT and to assess its heterogeneity across prespecified subgroups.MethodsWe pooled data from two trials (SKIP in Japan; DEVT in China). Individual patient data were pooled to assess outcomes and heterogeneity of treatment effect. The primary outcome was functional independence (modified Rankin Scale score 0–2) at 90 days. Safety outcomes included symptomatic intracranial hemorrhage (sICH) and 90-day mortality.ResultsWe included 438 patients (217 EVT alone; 221 combined IVT+EVT). The meta-analysis failed to demonstrate the non-inferiority of EVT alone over combined IVT+EVT in achieving 90-day functional independence (56.7% vs 51.6%; adjusted common odds ratio (cOR)=1.27, 95% CI 0.84 to 1.92, pnon-inferiority=0.06). Effect sizes favoring EVT alone were present with stroke onset to puncture time longer than 180 min (cOR=2.28, 95% CI 1.18 to 4.38, pinteraction ≤180 vs >180 min=0.02) and intracranial internal carotid artery ICA occlusions (for ICA cOR=3.04, 95% CI 1.10 to 8.43, pinteraction ICA vs MCA=0.08). The rates of sICH (6.5% vs 9.0%; cOR=0.77, 95% CI 0.37 to 1.61) and 90-day mortality (12.9% vs 13.6%; cOR=1.05, 95% CI 0.58 to 1.89) were comparable.ConclusionsThe cumulative data of these two recent Asian trials failed to unequivocally demonstrate the non-inferiority of EVT alone over combined IVT+EVT. However, our study suggests a potential role for more individualized decision-making. Specifically, Asian patients with stroke onset to EVT longer than 180 min, as well as those with intracranial ICA occlusions and those with atrial fibrillation might have better outcomes with EVT alone than with combined IVT+EVT.

Published
2024
Full Text
View/download PDF

21. Association of Intravenous Tirofiban with Functional Outcomes in Acute Ischemic Stroke Patients with Acute Basilar Artery Occlusion Receiving Endovascular Thrombectomy.

Author

Chen, Qiong, Meng, Renliang, Wu, Deping, Hu, Jinrong, Tao, Zhaojun, Xie, Dongjing, Tian, Yan, Han, Qin, Fu, Yuan, Zuo, Ling, Zhang, Min, Dai, Weipeng, Deng, Wei, Huang, Xianjun, Sang, Hongfei, Feng, Xinggang, Qiu, Zhongming, Wang, Tao, and Yuan, Junjie

Subjects
STROKE patients, ENDOVASCULAR surgery, ISCHEMIC stroke, BASILAR artery, ARTERIAL occlusions
Abstract

Introduction: The aim of this study was to test the hypothesis that intravenous tirofiban improves functional outcomes without promoting the risk of intracranial hemorrhage (ICH) in stroke secondary to basilar artery occlusion (BAO) receiving endovascular thrombectomy. Methods: Patients with acute BAO stroke who were treated with endovascular thrombectomy and had tirofiban treatment information were derived from "BASILAR": a nationwide, prospective registry. All eligible patients were divided into tirofiban and no-tirofiban groups according to whether tirofiban was used intravenously. The primary endpoint was the 90-day severity of disability as assessed by the modified Rankin scale score. Safety outcomes were the frequency of ICH and mortality. Results: Of 645 patients included in this cohort, 363 were in the tirofiban group and 282 were in the no-tirofiban group. Thrombectomy with intravenous tirofiban reduced the 90-day disability level over the range of the modified Rankin scale (adjusted common odds ratio, 2.08; 95% confidence interval (CI), 1.45–2.97; p < 0.001). The 90-day mortality of patients in the tirofiban group was lower than that in the no-tirofiban group (41.6% vs. 52.1%; adjusted hazard ratio, 0.60; 95% CI, 0.47–0.77; p < 0.001). The frequency of any ICH (6.7% vs. 13.7%; p = 0.004) and symptomatic ICH (4.8% vs. 10.1%; p = 0.01) in the tirofiban group was significantly lower than that in the no-tirofiban group. Conclusions: In patients with acute BAO stroke who underwent endovascular treatment, intravenous tirofiban might be associated with favorable outcome, reduced mortality, and a decreased frequency of ICH. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

22. Basilar artery occlusion management: Specialist perspectives from an international survey

Author

Edwards, Christopher, primary, Drumm, Brian, additional, Siegler, James E., additional, Schonewille, Wouter J., additional, Klein, Piers, additional, Huo, Xiaochuan, additional, Chen, Yimin, additional, Abdalkader, Mohamad, additional, Qureshi, Muhammad M., additional, Strbian, Daniel, additional, Liu, Xinfeng, additional, Hu, Wei, additional, Ji, Xunming, additional, Li, Chuanhui, additional, Fischer, Urs, additional, Nagel, Simon, additional, Puetz, Volker, additional, Michel, Patrik, additional, Alemseged, Fana, additional, Sacco, Simona, additional, Yamagami, Hiroshi, additional, Yaghi, Shadi, additional, Strambo, Davide, additional, Kristoffersen, Espen Saxhaug, additional, Sandset, Else C., additional, Mikulik, Robert, additional, Tsivgoulis, Georgios, additional, Masoud, Hesham E., additional, de Sousa, Diana Aguiar, additional, Marto, João Pedro, additional, Lobotesis, Kyriakos, additional, Roi, Dylan, additional, Berberich, Anne, additional, Demeestere, Jelle, additional, Meinel, Thomas R., additional, Rivera, Rodrigo, additional, Poli, Sven, additional, Ton, Mai Duy, additional, Zhu, Yuyou, additional, Li, Fengli, additional, Sang, Hongfei, additional, Thomalla, Götz, additional, Parsons, Mark, additional, Campbell, Bruce C. V., additional, Zaidat, Osama O., additional, Chen, Hui‐Sheng, additional, Field, Thalia S., additional, Raymond, Jean, additional, Kaesmacher, Johannes, additional, Nogueira, Raul G., additional, Jovin, Tudor G., additional, Sun, Dapeng, additional, Liu, Raynald, additional, Qureshi, Adnan I., additional, Qiu, Zhongming, additional, Miao, Zhongrong, additional, Banerjee, Soma, additional, and Nguyen, Thanh N., additional

Published
2023
Full Text
View/download PDF

23. Abstract TMP6: Association Of Tirofiban With Outcomes After Thrombectomy In Stroke Due To Atherosclerosis: An Exploratory Analysis Of The RESCUE BT Placebo-controlled Randomized Trial

Author

Sang, Hongfei, primary, Zi, Wenjie, additional, Wu, Junxiong, additional, Luo, Jun, additional, Hu, Zhizhou, additional, Wang, Tao, additional, Li, Rongzong, additional, Ke, Yingbing, additional, Zhu, Xiurong, additional, Xie, Dongjing, additional, Li, Fengli, additional, Yang, Qingwu, additional, and Qiu, Zhongming, additional

Published
2023
Full Text
View/download PDF

27. Abstract TP153: Basilar Artery Occlusion Management: Specialist Perspectives From After The BEST Of BASICS Study

Author

Edwards, Christopher, primary, Drumm, Brian, additional, Siegler, James E, additional, Schonewille, Wouter J, additional, Klein, Piers, additional, Huo, Xiaochuan, additional, Chen, Yimin, additional, Strbian, Daniel, additional, Liu, Xinfeng, additional, Hu, Wei, additional, Ji, Xunming, additional, Li, Chuanhui, additional, Fischer, Urs, additional, Nagel, Simon, additional, Puetz, Volker, additional, Michel, Patrik, additional, Alemseged, Fana, additional, Sacco, Simona, additional, Yamagami, Hiroshi, additional, Abdalkader, Mohamad, additional, Yaghi, Shadi, additional, Strambo, Davide, additional, Kristoffersen, Espen S, additional, Sandset, Else C, additional, Mikulik, Robert, additional, Tsivgoulis, Georgios, additional, Aguiar De Sousa, Diana, additional, Pedro Marto, João, additional, Lobotesis, Kyriakos, additional, Roi, Dylan, additional, Berberich, Anne, additional, Demeestere, Jelle, additional, Meinel, Thomas R, additional, Rivera, Rodrigo, additional, Poli, Sven, additional, Duy Ton, Mai, additional, Zhu, Yuyou, additional, Li, Fengli, additional, Sang, Hongfei, additional, Thomalla, Götz, additional, Parsons, Mark, additional, Campbell, Bruce C, additional, Chen, Hui-Sheng, additional, Raymond, Jean, additional, Nogueira, Raul G, additional, Jovin, Tudor G, additional, Qiu, Zhongming, additional, Miao, Zhongrong, additional, Banerjee, Soma, additional, and Nguyen, Thanh N, additional

Published
2023
Full Text
View/download PDF

28. Abstract 100: Endovascular Treatment With Intravenous Tirofiban Or Alteplase Versus Endovascular Treatment Alone For Acute Ischemic Stroke With Large Vessel Occlusion: A Pooled Analysis Of The Devt And Rescue Bt Trials

Author

Qiu, Zhongming, primary, Yuan, Junjie, additional, Xie, Dongjing, additional, Wu, Deping, additional, Luo, Weidong, additional, Zhaojun, Tao, additional, Liu, Shuai, additional, Han, Qin, additional, Sun, Dong, additional, Lei, Bo, additional, Li, Jinglun, additional, Miao, Jian, additional, Liu, Shudong, additional, Jin, Zhenglong, additional, Zeng, Guoyong, additional, Wen, Changming, additional, Yuan, Guangxiong, additional, Yang, Qingwu, additional, Nguyen, Thanh, additional, Saver, Jeffrey L, additional, Nogueira, Raul G, additional, Li, Fengli, additional, Sang, Hongfei, additional, and Zi, Wenjie, additional

Published
2023
Full Text
View/download PDF

29. Effect of endovascular treatment within 6 hours for acute basilar artery occlusion

Author

Yang, Jie, primary, Li, Fengli, additional, Qiu, Zhongming, additional, Wang, Yan, additional, Luo, Jun, additional, Wu, Youlin, additional, Zeng, Guoyong, additional, Wan, Yue, additional, Liu, Shuai, additional, Yue, Chengsong, additional, Song, Jiaxing, additional, Luo, Weidong, additional, Liu, Chang, additional, Li, Linyu, additional, Sun, Ruidi, additional, Huang, Jiacheng, additional, Sang, Hongfei, additional, Zhao, Chenhao, additional, Yang, Qingwu, additional, and Zi, Wenjie, additional

Published
2023
Full Text
View/download PDF

30. Association of Intravenous Tirofiban with Functional Outcomes in Acute Ischemic Stroke Patients with Acute Basilar Artery Occlusion Receiving Endovascular Thrombectomy

Author

Chen, Qiong, primary, Meng, Renliang, additional, Wu, Deping, additional, Hu, Jinrong, additional, Tao, Zhaojun, additional, Xie, Dongjing, additional, Tian, Yan, additional, Han, Qin, additional, Fu, Yuan, additional, Zuo, Ling, additional, Zhang, Min, additional, Dai, Weipeng, additional, Deng, Wei, additional, Huang, Xianjun, additional, Sang, Hongfei, additional, Feng, Xinggang, additional, Qiu, Zhongming, additional, Wang, Tao, additional, and Yuan, Junjie, additional

Published
2022
Full Text
View/download PDF

31. Design of the FP-RESTORE study: a protocol for prospective, observational study of real-world treatments with endovascular therapy in patients with femoropopliteal artery Tosaka III in-stent restenosis

Author

Li, Xu, primary, Zhou, Min, additional, Ding, Yong, additional, Wu, Ziheng, additional, Feng, Zibo, additional, Guo, Lianrui, additional, Li, Qiang, additional, Fang, Xin, additional, Sang, Hongfei, additional, Ye, Meng, additional, and Shi, Zhenyu, additional

Published
2022
Full Text
View/download PDF

33. Basilar Artery Occlusion Thrombectomy Technique: An International Survey of Practice Patterns

Author

Klein, Piers, primary, Herning, Ana, additional, Drumm, Brian, additional, Raymond, Jean, additional, Abdalkader, Mohamad, additional, Siegler, James E., additional, Chen, Yimin, additional, Huo, Xiaochuan, additional, Schonewille, Wouter J., additional, Liu, Xinfeng, additional, Hu, Wei, additional, Ji, Xunming, additional, Lapergue, Bertrand, additional, Li, Chuanhui, additional, Alemseged, Fana, additional, Strbian, Daniel, additional, Fischer, Urs, additional, Kaesmacher, Johannes, additional, Yamagami, Hiroshi, additional, Puetz, Volker, additional, Sacco, Simona, additional, Kristoffersen, Espen Saxhaug, additional, Demeestere, Jelle, additional, Lobotesis, Kyriakos, additional, Roi, Dylan, additional, Aydin, Kubilay, additional, Diana, Francesco, additional, Masoud, Hesham E., additional, Ma, Alice, additional, Novakovic‐White, Roberta, additional, Al‐Mufti, Fawaz, additional, Zhu, Yuyou, additional, Sang, Hongfei, additional, Sun, Dapeng, additional, Nguyen, Thang Huy, additional, Ton, Mai Duy, additional, Gentric, Jean‐Christophe, additional, Caroff, Jildaz, additional, Psychogios, Marios‐Nikos, additional, Consoli, Arturo, additional, Meyer, Lukas, additional, Fiehler, Jens, additional, English, Joey, additional, Gupta, Rishi, additional, Yan, Bernard, additional, Campbell, Bruce, additional, Jadhav, Ashutosh P., additional, Lee, Jin Soo, additional, Thomalla, Götz, additional, Nagel, Simon, additional, Yang, Qingwu, additional, Zaidat, Osama O., additional, Qiu, Zhongming, additional, Miao, Zhongrong, additional, Banerjee, Soma, additional, and Nguyen, Thanh N., additional

Published
2022
Full Text
View/download PDF

34. A prospective, multicenter, real-world observational study evaluating the impact of tibial runoff on clinical outcomes after endovascular therapy for femoropopliteal lesions: Research protocol

Author

Liu, Yang, primary, Wang, Qiqi, additional, Wu, Ziheng, additional, Fen, Zibo, additional, Guo, Lianrui, additional, Li, Qiang, additional, Fang, Xin, additional, Sang, Hongfei, additional, Dai, Yudi, additional, He, Chunshui, additional, and Ye, Meng, additional

Published
2022
Full Text
View/download PDF

35. Protocol of the evolution study: A prospective, multicenter, observational study evaluating the effect and health economics of endovascular treatment in patients with moderate and severe calcification of femoropopliteal artery

Author

Pan, Jun, primary, Guo, Lianrui, additional, Fang, Xin, additional, Feng, Zibo, additional, Li, Qiang, additional, He, Chunshui, additional, Sang, Hongfei, additional, Shi, Weihao, additional, Shi, Zhenyu, additional, Wang, Bing, additional, Qiu, Chenyang, additional, Wu, Ziheng, additional, and Ye, Meng, additional

Published
2022
Full Text
View/download PDF

36. Effect of the anastomosis between the posterior inferior cerebellar artery and the superior cerebellar artery on outcomes of acute basilar artery occlusion after endovascular treatment

Author

Huang, Jiacheng, primary, Kong, Weilin, additional, Yang, Jie, additional, Wang, Maolin, additional, Huang, Xianjun, additional, Wang, Yan, additional, Luo, Jun, additional, Wu, Youlin, additional, Zeng, Guoyong, additional, Wan, Yue, additional, Song, Jiaxing, additional, Li, Linyu, additional, Hu, Jinrong, additional, Liu, Shuai, additional, Luo, Weidong, additional, Tian, Yan, additional, Sang, Hongfei, additional, Qiu, Zhongming, additional, Li, Fengli, additional, Schonewille, Wouter, additional, Liu, Chang, additional, and Zi, Wenjie, additional

Published
2022
Full Text
View/download PDF

37. Outcome of endovascular treatment in acute basilar artery occlusion with National Institutes of Health Stroke Scale score 10–19

Author

Huang, Jiacheng, primary, Kong, Weilin, additional, Qiu, Zhongming, additional, Liu, Da, additional, Li, Huagang, additional, Zhou, Peiyang, additional, Yan, Zhizhong, additional, Wang, Yan, additional, Dai, Weipeng, additional, Zheng, Chong, additional, Li, Rongzong, additional, Wang, Jian, additional, Song, Jiaxing, additional, Yuan, Junjie, additional, Luo, Weidong, additional, Liu, Shuai, additional, Li, Linyu, additional, Sang, Hongfei, additional, Li, Fengli, additional, Wu, Deping, additional, Yang, Qingwu, additional, and Zi, Wenjie, additional

Published
2022
Full Text
View/download PDF

38. Circular RNA hsa_circ_0003574 as a biomarker for prediction and diagnosis of ischemic stroke caused by intracranial atherosclerotic stenosis

Author

Li, Lingfei, primary, Si, Xiaoli, additional, Ruan, Jie, additional, Ni, Zhumei, additional, Li, Xiaoqin, additional, Sang, Hongfei, additional, Xia, Wenqing, additional, Huang, Jinyu, additional, Liu, Keqin, additional, Lu, Shan, additional, Jiang, Lin, additional, Shao, Anwen, additional, and Yin, Congguo, additional

Published
2022
Full Text
View/download PDF

39. RESCUE BT 2, a multicenter, randomized, double-blind, double-dummy trial of intravenous tirofiban in acute ischemic stroke: Study rationale and design

Author

Zi, Wenjie, primary, Song, Jiaxing, additional, Qiu, Zhongming, additional, Kong, Weilin, additional, Huang, Jiacheng, additional, Luo, Weidong, additional, Liu, Shuai, additional, Sang, Hongfei, additional, Yang, Jie, additional, Li, Linyu, additional, Tian, Yan, additional, Hu, Jinrong, additional, Saver, Jeffrey L, additional, Nogueira, Raul G, additional, Li, Fengli, additional, and Yang, Qingwu, additional

Published
2022
Full Text
View/download PDF

41. RESCUE BT 2, a multicenter, randomized, double-blind, double-dummy trial of intravenous tirofiban in acute ischemic stroke: Study rationale and design.

Author

Zi, Wenjie, Song, Jiaxing, Qiu, Zhongming, Kong, Weilin, Huang, Jiacheng, Luo, Weidong, Liu, Shuai, Sang, Hongfei, Yang, Jie, Li, Linyu, Tian, Yan, Hu, Jinrong, Saver, Jeffrey L, Nogueira, Raul G, Li, Fengli, and Yang, Qingwu

Subjects
ISCHEMIC stroke, THROMBOLYTIC therapy, TIROFIBAN, STROKE patients, ACUTE coronary syndrome, EXPERIMENTAL design, INTRACEREBRAL hematoma
Abstract

Background: Tirofiban is a glycoprotein IIb/IIIa receptor inhibitor that has been shown to be effective in the treatment of acute coronary syndromes. However, it remains unknown whether it improves outcomes in patients with acute ischemic stroke. Objective: This trial investigates the efficacy and safety of tirofiban compared with aspirin for acute ischemic stroke within 24 h after symptom onset. Methods and design: The Efficacy and Safety of Tirofiban Compared with Aspirin in the Treatment of Acute Ischemic Stroke (RESCUE BT 2) Trial is an investigator-initiated, prospective, randomized, double-blind, double-dummy, multicenter clinical trial. Up to 1158 eligible patients will be consecutively randomized to receive antiplatelet therapy with tirofiban or aspirin in 1:1 ratio across approximately 100 stroke centers in China. Outcomes: The primary endpoint is the proportion of patients with excellent functional outcomes defined as a modified Rankin scale score of 0 to 1 at 90 days after randomization. Lead safety endpoints include mortality at 90 days and symptomatic intracerebral hemorrhage within 48 h after treatment. Trial registry number: ChiCTR2000029502 (www.chictr.org.cn). [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

42. Effect of atrial fibrillation on outcomes after mechanical thrombectomy and long-term ischemic recurrence in patients with acute basilar artery occlusion

Author

Zhao, Chenhao, primary, Luo, Weidong, additional, Liu, Xing, additional, Luo, Jun, additional, Song, Jiaxing, additional, Yuan, Junjie, additional, Liu, Shuai, additional, Huang, Jiacheng, additional, Kong, Weilin, additional, Hu, Jinrong, additional, Yang, Jie, additional, Sun, Ruidi, additional, Yue, Chengsong, additional, Xie, Dongjing, additional, Li, Linyu, additional, Sang, Hongfei, additional, Qiu, Zhongming, additional, Li, Fengli, additional, Wu, Deping, additional, Zi, Wenjie, additional, and Yang, Qingwu, additional

Published
2022
Full Text
View/download PDF

45. Hyperdense Artery Sign and Clinical Outcomes After Endovascular Treatment in Acute Basilar Artery Occlusion

Author

Hu, Jinrong, primary, He, Wencheng, additional, Zheng, Bo, additional, Huang, Fang, additional, Lv, Kefeng, additional, Liao, Jiasheng, additional, Chen, Zhao, additional, Jiang, He, additional, Wang, Kuiyun, additional, Wang, Hongjun, additional, Lei, Yang, additional, Liao, Jiachuan, additional, Sang, Hongfei, additional, Liu, Shuai, additional, Luo, Weidong, additional, Sun, Ruidi, additional, Yang, Jie, additional, Huang, Jiacheng, additional, Song, Jiaxing, additional, Li, Fengli, additional, Zi, Wenjie, additional, Long, Chen, additional, and Yang, Qingwu, additional

Published
2022
Full Text
View/download PDF

47. Abstract TP143: Endovascular Treatment With Versus Without Tirofiban For Stroke Patients With Large Vessel Occlusion: The Multicenter, Randomized, Placebo-controlled, Double-blind RESCUE BT Clinical Trial

Author

Qiu, Zhongming, primary, Li, Fengli, additional, Sang, Hongfei, additional, Yuan, Junjie, additional, Luo, Weidong, additional, Song, Jiaxing, additional, huang, jia cheng, additional, Liu, Shuai, additional, Li, Linyu, additional, Wu, Deping, additional, Yue, Chengsong, additional, Yang, Jie, additional, Zi, Wenjie, additional, and Yang, Qingwu, additional

Published
2022
Full Text
View/download PDF

48. Endovascular treatment with versus without tirofiban for stroke patients with large vessel occlusion: The multicenter, randomized, placebo-controlled, double-blind RESCUE BT study protocol

Author

Qiu, Zhongming, primary, Li, Fengli, additional, Sang, Hongfei, additional, Liu, Wenhua, additional, Huang, Wenguo, additional, Li, Huagang, additional, Zhang, Min, additional, Zhou, Peiyang, additional, Lei, Bo, additional, Zhou, Zhiming, additional, Saver, Jeffrey L, additional, Nogueira, Raul G, additional, Zi, Wenjie, additional, and Yang, Qingwu, additional

Published
2022
Full Text
View/download PDF

49. Efficacy and Safety of Intravenous Tirofiban Before Endovascular Thrombectomy for Large Vessel Occlusion Stroke (RESCUE BT): A Multicentre, Randomised, Double-Blind, Placebo-Controlled Trial

Author

Qiu, Zhongming, primary, Li, Fengli, additional, Sang, Hongfei, additional, Luo, Weidong, additional, Liu, Shuai, additional, Liu, Wenhua, additional, Guo, Zhangbao, additional, Li, Huagang, additional, Sun, Dong, additional, Huang, Wenguo, additional, Zhang, Min, additional, Dai, Weipeng, additional, Zhou, Peiyang, additional, Deng, Wei, additional, Zhou, Zhiming, additional, Huang, Xianjun, additional, Lei, Bo, additional, Li, Jinglun, additional, Yuan, Zhengzhou, additional, Song, Bo, additional, Miao, Jian, additional, Liu, Shudong, additional, Jin, Zhenglong, additional, Zeng, Guoyong, additional, Zeng, Hongliang, additional, Yuan, Junjie, additional, Wen, Changming, additional, Yu, Yang, additional, Yuan, Guangxiong, additional, Wu, Junxiong, additional, Long, Chen, additional, Luo, Jun, additional, Tian, Zhenxuan, additional, Zheng, Chong, additional, Hu, Zhizhou, additional, Wang, Shouchun, additional, Wang, Tao, additional, Qi, Li, additional, Li, Rongzong, additional, Wan, Yue, additional, Ke, Yingbing, additional, Wu, Youlin, additional, Zhu, Xiurong, additional, Kong, Weilin, additional, Huang, Jiacheng, additional, Peng, Daizhou, additional, Chang, Mingze, additional, Ge, Hanming, additional, Shi, Zhonghua, additional, Yan, Zhizhong, additional, Du, Jie, additional, Jin, Ying, additional, Ju, Dongsheng, additional, Huang, Chuming, additional, Hong, Yifan, additional, Liu, Tianzhu, additional, Zhao, Wenlong, additional, Wang, Jian, additional, Zheng, Bo, additional, Wang, Li, additional, Liu, Shugai, additional, Luo, Xiaojun, additional, Luo, Shiwei, additional, Xu, Xinwei, additional, Hu, Jinrong, additional, Pu, Jie, additional, Chen, Shengli, additional, Sun, Yaxuan, additional, Jiang, Shunfu, additional, Wei, Liping, additional, Fu, Xinmin, additional, Bai, Yongjie, additional, Yang, Shunyu, additional, Hu, Wei, additional, Zhang, Guling, additional, Pan, Chengde, additional, Zhang, Shuai, additional, Wang, Yan, additional, Cao, Wenfeng, additional, Yang, Shiquan, additional, Zhang, Jun, additional, Guo, Fuqiang, additional, Wen, Hongbin, additional, Zhang, Jinghua, additional, Song, Jiaxing, additional, Yue, Chengsong, additional, Li, Linyu, additional, Wu, Deping, additional, Tian, Yan, additional, Yang, Jie, additional, Lu, Mengjie, additional, Saver, Jeffrey, additional, Gomes Nogueira, Raul, additional, Zi, Wenjie, additional, and Yang, QingWu, additional

Published
2022
Full Text
View/download PDF

50. Outcomes of Endovascular Therapy in Acute Basilar Artery Occlusion With Severe Symptoms

Author

Kong, Weilin, primary, Yuan, Junjie, additional, Huang, Jiacheng, additional, Song, Jiaxing, additional, Zhao, Chenhao, additional, Sang, Hongfei, additional, Luo, Weidong, additional, Xie, Dongjing, additional, Gao, Fei, additional, Li, Huagang, additional, Luo, Jun, additional, Liu, Shudong, additional, Xue, Dongzhang, additional, Yu, Yinquan, additional, Li, Fengli, additional, Qiu, Zhongming, additional, Zi, Wenjie, additional, and Yang, Qingwu, additional

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results