118 results on '"Sandu K"'
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2. Tratamiento de las estenosis laríngeas y traqueales del adulto
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Lagier, A., Gorostidi, F., Demez, P., and Sandu, K.
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- 2020
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3. Surgical options in suprastomal collapse-induced severe airway obstruction
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Onder, Serap Sahin, Ishii, A., and Sandu, K.
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- 2020
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4. Claviculotracheopexy for complex airway reconstructions
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Sandu, K., Vinckenbosch-Jaballah, Pauline, and Duchoud, L.
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- 2020
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5. Criticality in tailoring the treatment for tracheoesophageal fistulas in children
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Asik, M. B., Almre, I., Duchoud, L., and Sandu, K.
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- 2020
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6. Decoding supraglottic stenosis
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Colliard, A., Ishii, A., De Sandre, Cecile, Gorostidi, F., and Sandu, K.
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- 2020
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7. Stenosi laringee dell’adulto
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Lagier, A., Gorostidi, F., Demez, P., and Sandu, K.
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- 2019
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8. Management of severe congenital laryngeal webs – a 12 year review
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de Trey, L.A., Lambercy, K., Monnier, P., and Sandu, K.
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- 2016
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9. Paralyzed neonatal larynx in adduction. Case series, systematic review and analysis
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Nisa, L., Holtz, F., and Sandu, K.
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- 2013
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10. Treatment outcomes in patients with laryngotracheal lesions and compromised airway during and prior to the coronovirus disease 2019 pandemic: a tertiary institution's experience
- Author
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Gombert, E, primary, Ishii, A, additional, Guilcher, P, additional, Gorostidi, F, additional, Cantarella, G, additional, Pignataro, L, additional, and Sandu, K, additional
- Published
- 2021
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11. Réinnervations laryngées [Laryngeal reinnervation]
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Salati, V., Beharry, A., Fries, S., Sandu, K., and Gorostidi, F.
- Abstract
The surgical management of unilateral and bilateral vocal cord paralysis depends on the severity of the condition, the potential for spontaneous recovery, the patient's age and vocal expectations. Standardized re-innervation surgeries, unilateral non-selective and bilateral selective, are viable alternatives to static procedures currently under evaluation in prospective studies. Neurorraphy of the ansa cervicalis loop to the recurrent laryngeal nerve allows lasting vocal recovery and potentially superior results to medialization and thyroplasty, by maintaining the visco-elastic properties of the vocal cord and preventing its atrophy. Selective bilateral reinnervation shows potential for recovery of inspiratory abduction with improved respiratory function without vocal deterioration.
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- 2020
12. A new dimension of success in the management of airway disease in children with neurological deficit
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Kokje, Vivianne Beatrix Christina, primary, Mermod, Maxime, additional, Bertinazzi, Martina, additional, and Sandu, K., additional
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- 2020
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13. Propranolol treatment for subglottic haemangioma
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Guye, E, Chollet-Rivier, M, Schröder, D, Sandu, K, Hohlfeld, J, and de Buys Roessingh, A
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- 2011
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14. Criticality in tailoring the treatment for tracheoesophageal fistulas in children
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Asik, M. B., primary, Almre, I., additional, Duchoud, L., additional, and Sandu, K., additional
- Published
- 2019
- Full Text
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15. Decoding supraglottic stenosis
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Colliard, A., primary, Ishii, A., additional, De Sandre, Cecile, additional, Gorostidi, F., additional, and Sandu, K., additional
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- 2019
- Full Text
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16. Endoscopic treatment of post-supraglottoplasty stenosis
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Sandu, K., primary, Perez, M.H., additional, Longchamp, D., additional, Chollet, M., additional, and Gorostidi, F., additional
- Published
- 2018
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17. Management of severe congenital laryngeal webs - a 12 year review
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de Trey, L A, Lambercy, K, Monnier, P, Sandu, K, University of Zurich, and de Trey, L A
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2733 Otorhinolaryngology ,610 Medicine & health ,10220 Clinic for Surgery ,2735 Pediatrics, Perinatology and Child Health - Published
- 2016
18. Anatomical landmarks for transnasal endoscopic skull base surgery
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Sandu, K.
- Abstract
La résection par voie endoscopique transnasale de tumeurs envahissant la base du crâne antérieure a été récemment décrite. Cette chirurgie requiert une connaissance précise des repères anatomiques endoscopiques afin réduire le risque de complications vasculaires et neurologiques.¦Nous avons réalisé une étude anatomique endoscopique sur 6 têtes dont 3 injectées avec du silicone coloré. Les repères anatomiques pour les abords de 3 régions d'importance clinique ont été étudiés. Les repères pour l'abord de l'apex orbitaire sont le recessus carotidien latéral, l'empreinte du nerf optique, « l'optic strut » et le V2. Leurs rapports avec le canal optique, l'artère carotide interne et les fentes orbitaires supérieures et inférieures sont décrits. Les repères pour l'abord de l'apex pétreux sont le V2 et le nerf vidien qui permettent repérer la portion intrapétreuse de l'artère carotide interne. Les repères pour l'abord de la fosse ptérygomaxillaire sont le V2 et le foramen rotundum, l'artère et le trou sphénopalatins et l'artère maxillaire interne.¦Cette nouvelle approche permettant d'aborder des lésions médianes et paramédianes ouvre de nouvelles perspectives pour des équipes de neurochirurgiens et d'ORL. Ces voies d'abords s'appliquent aussi bien à des résections décompressives à but palliatif qu'à l'exérèse de tumeurs benignes et malignes, bien que les résultats à long terme doivent encore être validés pour cette dernière indication.
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- 2011
19. Centric diatoms of some European protected area (Croatia, Romania and Spain)
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Kiss, Keve Tihamer, Ács, Éva, Burić, Zrinka, Gligora, Marija, Grigorszky, Istvan, Plenković-Moraj, Anđelka, Rosa-Miracle, M., Sandu, K., Szabó, K.É., and Vicente, E.
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Centric diatom ,protected area ,Croatia ,Romania ,Spain - Abstract
Centric diatom communities of were studied in a few dozen of different lakes in Croatia, Romania and Spain during the last years. Several lakes are situated on protected areas, National Parks, Natura 2000 sites of these countries. The aim of these investigations was first to determine of centric diatom communities of lakes, then to analyse the species composition from a nature conservation point of view. We elaborated a typology of habitats based mainly on substrate, mineralization, water regime and climatology. Then, within the resulting types of environments, we pretend to establish different categories of their ecological status based on nutrients and chlorophyll concentration and other variables related to nature protection. Several lakes were never investigated for centric diatoms, therefore new species was found for Romania for example in Danube Delta (Lake Erentsuk - Thalassiosira gessnerii). Several similarities were found in carstic lakes of Croatia (Lake Plitvice – dominant species: Cyclotella plitvicensis) and Spain (Lake Marquesado – dominant species: C. plitvicensis). We can mention Cyclotella hispanica, described from Lake Banoles (Spain), which is probably endemic species (never found in other countries in Europe). Several species were found which are rare in Europe and are listed in Red List of algae.
- Published
- 2006
20. Endoscopic laryngotracheal cleft repair without tracheotomy or intubation.
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Sandu K and Monnier P
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- 2006
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21. Clival chordoma with an atypical presentation: a case report
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Alshammari Jaber, Monnier Philippe, Daniel Roy T, and Sandu Kishore
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Medicine - Abstract
Abstract Introduction Clival chordomas present with headache, commonly VI cranial nerve palsy or sometimes with lower cranial nerve involvement. Very rarely, they present with cerebrospinal fluid rhinorrhoea due to an underlying chordoma-induced skull base erosion. Case presentation A 60-year old Caucasian woman presented with meningitis secondary to cerebrospinal fluid rhinorrhoea. At first, radiological imaging did not reveal a tumoral condition, though intraoperative exploration and tissue histology revealed a chordoma which eroded her clivus and had a transdural extension. Conclusion Patients who present with meningitis and cerebrospinal fluid rhinorrhoea could have an underlying erosive lesion which can sometimes be missed on initial radiological examination. Surgical exploration allows collecting suspicious tissue for histological diagnosis which is important for the actual treatment. A revision endoscopic excision of a clival chordoma is challenging and has been highlighted in this report.
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- 2012
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22. [Recurrent respiratory papillomatosis].
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Salati V, Janjic O, Gorostidi F, and Sandu K
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- Humans, Papillomavirus Vaccines administration & dosage, Quality of Life, Papillomavirus Infections diagnosis, Papillomavirus Infections complications, Respiratory Tract Infections diagnosis, Respiratory Tract Infections virology, Respiratory Tract Infections therapy
- Abstract
Recurrent respiratory papillomatosis is a chronic infection of the airway mucosa by the human papilloma virus, in the form of recurrent exophytic papilloma. Two clinical forms are distinguished: juvenile and adult onset. Depending on their size and location, papilloma can cause dysphonia, pharyngeal discomfort, until obstruction of the airway. There is no curative treatment. The management strategy is to surgically remove symptomatic disease by transoral approach, but some recurrent disease require multiple interventions and -adjuvant therapies. The symptoms caused by the disease as well as treatments' side effects have a major impact on patient's quality of life. Vaccination against HPV currently represents the best strategy to prevent disease., Competing Interests: Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article.
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- 2024
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23. Open airway surgery for post-COVID laryngotracheal stenosis.
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Nisa L, Leroyer H, and Sandu K
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- Male, Humans, Female, Adolescent, Young Adult, Adult, Middle Aged, Aged, Constriction, Pathologic, Treatment Outcome, Retrospective Studies, Postoperative Complications epidemiology, Intubation, Tracheal Stenosis etiology, Tracheal Stenosis surgery, COVID-19 complications, Laryngostenosis etiology, Laryngostenosis surgery
- Abstract
Introduction: This study reports our experience with open reconstructive surgery in patients with laryngotracheal stenosis (LTS) following prolonged intubation and/or tracheostomy in the context of COVID-19., Methods: All patients underwent a preoperative endoscopic airway assessment. Posterior glottic lesions were graded according to the Bogdasarian classification, subglottic-tracheal lesions according to the Cotton-Myers classification and postoperative complications reported by the Clavien-Dindo classification. We report postoperative outcomes and functional results in this patient subset., Results: We include 14 patients diagnosed to have post COVID LTS, one female and 13 males. This group was compared with a control group, diagnosed with LTS following prolonged intubation. In the COVID group, mean age of patients at the time of the airway surgery was 52.1 ± 16.8 years (range: 13.7-76.3). More than half the patients were multi-morbid with hypertension and obesity being the most common conditions. Eleven patients had multi-site stenoses. Open surgical interventions performed were tracheal resection and anastomosis, laryngotracheal reconstruction and extended cricotracheal resection, and postoperative complications were seen in 12 (85.6%) patients. 70% patients with pre-existing tracheostomy were decannulated. Oral swallowing was not tolerated in one-fifth of the patients and a significant number of them have poor voice quality., Conclusion: Post-COVID pandemic, airway surgeons are seeing an increased number of patients with complex LTS, and we report significant postoperative complications in this patient subset. Decannulation rates, voice and swallowing results are poor in patients with glottic involvement as compared to isolated tracheal stenosis., (© 2024. The Author(s).)
- Published
- 2024
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24. External laryngotracheal trauma: a case series and an algorithmic management strategy.
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Pincet L, Lecca G, Chrysogelou I, and Sandu K
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- Male, Humans, Female, Retrospective Studies, Tracheostomy, Vocal Cords injuries, Thyroid Cartilage, Trachea surgery, Larynx surgery, Larynx injuries
- Abstract
Objectives: External laryngotracheal trauma (ELT), blunt or penetrating, is a rare but potentially life-threatening injury. Immediate care in the emergency department can be challenging because it requires managing a potentially unstable airway and may have associated vascular injuries with massive bleeding. Here, we look at the details of injury, treatment measures, and outcomes in patients following ELT., Methods: We retrospectively analyzed 22 patients treated at our center for ELT from January 2005 up to December 2021 with varying grades of injury. We looked at their status at presentation, management strategy and functional status., Results: In our report, we include 18 men and 4 women having varying Schaefer injury grades. Eight patients had tracheostomy at presentation and eight had vocal fold immobility. Two patients were treated endoscopically, 12 had open surgery and 8 received no treatment. Of the patients undergoing open surgery, thyroid cartilage fracture was seen in 9 patients, thyroid plus cricoid fracture and cricotracheal separation were seen in 3 patients each. All patients were safely decannulated and spontaneous recovery of vocal cord palsy was seen in some patients., Conclusion: The success of managing ELT relies on fast decision-making, correct patient evaluation, securing the airway and maintaining the hemodynamic stability. Early surgical intervention must be aimed at optimally treating the larygotracheal injuries to prevent long-term disastrous consequences., (© 2024. The Author(s).)
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- 2024
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25. Congenital laryngo-tracheo-esophageal clefts: updates from a quaternary care pediatric airway unit.
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Ishii A, Christophel E, Chollet M, and Sandu K
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- Humans, Child, Esophagus surgery, Trachea surgery, Trachea abnormalities, Retrospective Studies, Larynx surgery, Abnormalities, Multiple diagnosis, Respiratory System Abnormalities
- Abstract
Purpose: To review the operative techniques, outcomes, and complications following surgery in pediatric patients with laryngo-tracheo-esophageal clefts (LTEC). We describe a new combined approach to treat long LTECs., Methods: Twenty-five patients underwent surgical repair for LTEC from March 2012 to July 2022 at our hospital. Every patient underwent a diagnostic endoscopy under general anesthesia and spontaneous ventilation to assess the LTEC and synchronous aero-digestive comorbidities/malformations. All patients underwent at least one surveillance endoscopy after the repair at our institution., Results: The patients had multiple other malformations, specifically gastro-intestinal, synchronous airway, and cardiac. The cleft distribution according to the modified Benjamin and Inglis classification was type I (n = 5, 20%), type II (n = 6, 24%), type IIIa (n = 8, 32%), type IIIb (n = 4, 16%), and type IVa (n = 2, 8%). The median follow-up was 44.6 months. Five patients (20%) had undergone previous cleft corrective surgery(s). Seven patients (28%) had partial to complete breakdown of the repair, needing additional intervention(s), and two required a combined-open plus endoscopic repair. Preoperatively, most patients (n = 18, 72%) needed a feeding assistance. At latest follow-up, feeding assistance was weaned off in 13 out of 18 patients, which was a 72% improvement. Ten patients (40%) needed ventilation assistance before the surgery. Post-operatively, ventilatory assistance was weaned off in 6 patients, meaning a 60% improvement., Conclusion: LTEC are rare malformations, and their management needs precise diagnosis, appropriate surgical planning, and execution, and dedicated post-operative care. Primary and revision repair of long clefts with tracheal extension may require a combined approach., (© 2023. The Author(s).)
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- 2024
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26. Oropharyngolaryngeal manifestations in severe toxic epidermal necrolysis: a single-center's retrospective case series.
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Glasson N, De Sandre C, Pantet O, Reinhard A, Lambercy K, Sandu K, and Gorostidi F
- Abstract
Background: Toxic epidermal necrolysis is a rare and life-threatening mucocutaneous disease. Although mucosal ear, nose, and throat (ENT) involvement is common, little is known about the characteristics, treatment modalities, and outcomes of these lesions. The aim of this study was to evaluate ENT mucosal lesions in severe toxic epidermal necrolysis patients and analyze their characteristics, treatment modalities, and outcomes, as well as proposing a management algorithm to prevent long-term debilitating sequalae of these lesions., Methods: This is a retrospective review of toxic epidermal necrolysis cases treated at the tertiary burns unit of the Lausanne University Hospital CHUV, Switzerland, between 2006 and 2019., Results: Out of 19 patients with severe toxic epidermal necrolysis, 17 (89%) underwent a complete ENT examination at admission and 14 (82%) had ENT mucosal involvement. Five (26.3%) patients died during the stay in the intensive care unit. Of the 16 patients who received maximal care, 13 (81%) required orotracheal intubation for a median time of 16 (IQR: 14) days. Out of the 14 patients who survived, four (29%) had long-term ENT complications consisting of synechiaes necessitating subsequent endoscopic procedures. Those four patients all required mechanical ventilation with an orotracheal tube and suffered from hypopharyngeal synechiaes as well as oral and endonasal synechiaes in individual cases., Conclusion: This study suggests a high prevalence of ENT synechiaes in patients with severe toxic epidermal necrolysis and requiring orotracheal intubation. Periodic ENT examination could prevent mature synechiae formation in these patients. We propose an algorithm to prevent long-term sequalae in ENT mucosal involvement., (© 2023 The Authors. International Journal of Dermatology published by Wiley Periodicals LLC on behalf of the International Society of Dermatology.)
- Published
- 2023
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27. Congenital Malformations of the Cricoid Cartilage: Upper Airway Obstruction and Treatment Strategy.
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Gombert E, Gorostidi F, and Sandu K
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- Child, Humans, Cricoid Cartilage surgery, Retrospective Studies, Treatment Outcome, Airway Obstruction etiology, Airway Obstruction surgery, Laryngostenosis etiology, Laryngostenosis surgery, Laryngostenosis diagnosis
- Abstract
Objectives: To review treatment and outcomes in patients with congenital cricoid cartilage malformation., Methods: Retrospective analysis of patients with diagnosis of congenital cricoid malformation (CCM) treated in a single tertiary pediatric referral center between 1985 and 2022. Patients were grouped according to the morphology of the cricoid cartilage that was diagnosed during endoscopy. We reviewed the treatment strategy(s), decannulation rate, complications, and functional outcomes., Results: Twenty-nine patients were grouped into four morphological subtypes of cricoid cartilage: 10 patients had a hypoplastic cricoid, eight had an elliptic shape, five had severe anterior thickening, and six an accentuated V-shape posterior cricoid plate. Twenty-four patients underwent surgery, and five were closely followed up without surgical treatment. Eight patients had a tracheostomy prior to surgery, and the majority had a hypoplastic cricoid. Most patients (20 out of 24) required additional procedures postoperatively to achieve an age-appropriate airway. Thirteen patients needed endoscopic dilatation(s) and granulation tissue removal; four needed more aggressive treatment, and three patients required revision open surgery. Decannulation was achieved after a median of 4.5 months in all previously tracheostomized patients. Endoscopy at the last follow-up showed an age-appropriate airway in 27 patients; 20 patients had normal oral feeding, and 11 patients had a normal voice., Conclusion: Endoscopy is important to diagnose CCM and most of the time patients would need only watchful waiting. In this report, surgery was required for patients who continued to remain symptomatic and had a compromised airway. The type of surgery depends on the type of cricoid malformation and the grade of stenosis., Level of Evidence: 4 Laryngoscope, 133:3185-3191, 2023., (© 2023 The Authors. The Laryngoscope published by Wiley Periodicals LLC on behalf of The American Laryngological, Rhinological and Otological Society, Inc.)
- Published
- 2023
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28. Revision surgery for laryngotracheal stenosis in children: A single center's 44 years experience.
- Author
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Gluvajić D, Bhate JJ, and Sandu K
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- Child, Humans, Reoperation adverse effects, Retrospective Studies, Constriction, Pathologic surgery, Treatment Outcome, Laryngostenosis surgery, Laryngostenosis etiology, Tracheal Stenosis surgery, Tracheal Stenosis complications
- Abstract
Objectives: Outcome measures of revision open airway surgery in pediatric laryngotracheal stenosis (LTS) are reported., Methods: Data on 46 pediatric LTS patients undergoing revision open airway surgery were collected retrospectively. The measured outcomes were decannulation rate, time to decannulation, postoperative complications, additional surgery to achieve decannulation, and functional results., Results: The most common revision surgery was partial cricotracheal resection (PCTR) in 21/46, followed by extended PCTR (ePCTR) in 20/46, and laryngotracheal reconstruction (LTR) in 5/46 patients. A 90.7% overall decannulation rate (ODR) and a 74.4% operation-specific decannulation rate (OSDR) were achieved. Delayed decannulation was identified in children aged 5 years or less (p = 0.038) and in patients with previous primary open airway surgery (p = 0.039). Complications were observed in 52.2% of patients. To achieve optimal airway patency, additional open or endoscopic airway surgeries were necessary in 30.4% and 47.7% of patients, respectively. Age 5 years or less (p = 0.034), multiple comorbidities (p = 0.044), revision ePCTR (p = 0.023), and laryngeal stenting (p = 0.018) were risk factors requiring additional open surgery to achieve age-appropriate airway. Failed primary open airway surgery (p = 0.034) and comorbidities (p = 0.044) were risk factors for a higher rate of additional endoscopic surgeries. Postoperatively 63.0% of patients achieved normal breathing, 82.2% were dysphonic and 91.1% were orally fed., Conclusions: In this report, the patient's age under 5 years, previous primary open airway surgery, medical comorbidities, and laryngeal stenting had a significant negative impact on revision open airway surgery outcomes., Level of Evidence: Level 4 Laryngoscope, 133:3200-3207, 2023., (© 2023 The Authors. The Laryngoscope published by Wiley Periodicals LLC on behalf of The American Laryngological, Rhinological and Otological Society, Inc.)
- Published
- 2023
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29. Enhancing Robustness of Adhesive Hydrogels through PEG-NHS Incorporation.
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Uslu E, Rana VK, Guo Y, Stampoultzis T, Gorostidi F, Sandu K, and Pioletti DP
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- Adhesives, State Medicine, Biocompatible Materials, Acrylamides, Polyethylene Glycols pharmacology, Hydrogels pharmacology
- Abstract
Tissue wounds are a significant challenge for the healthcare system, affecting millions globally. Current methods like suturing and stapling have limitations as they inadequately cover the wound, fail to prevent fluid leakage, and increase the risk of infection. Effective solutions for diverse wound conditions are still lacking. Adhesive hydrogels, on the other hand, can be a potential alternative for wound care. They offer benefits such as firm sealing without leakage, easy and rapid application, and the provision of mechanical support and flexibility. However, the in vivo durability of hydrogels is often compromised by excessive swelling and unforeseen degradation, which limits their widespread use. In this study, we addressed the durability issues of the adhesive hydrogels by incorporating acrylamide polyethylene glycol N -hydroxysuccinimide (PEG-NHS) moieties (max. 2 wt %) into hydrogels based on hydroxy ethyl acrylamide (HEAam). The results showed that the addition of PEG-NHS significantly enhanced the adhesion performance, achieving up to 2-fold improvement on various soft tissues including skin, trachea, heart, lung, liver, and kidney. We further observed that the addition of PEG-NHS into the adhesive hydrogel network improved their intrinsic mechanical properties. The tensile modulus of these hydrogels increased up to 5-fold, while the swelling ratio decreased up to 2-fold in various media. These hydrogels also exhibited improved durability under the enzymatic and oxidative biodegradation induced conditions without causing any toxicity to the cells. To evaluate its potential for clinical applications, we used PEG-NHS based hydrogels to address tracheomalacia, a condition characterized by inadequate mechanical support of the airway due to weak/malacic cartilage rings. Ex vivo study confirmed that the addition of PEG-NHS to the hydrogel network prevented approximately 90% of airway collapse compared to the case without PEG-NHS. Overall, this study offers a promising approach to enhance the durability of adhesive hydrogels by the addition of PEG-NHS, thereby improving their overall performances for various biomedical applications.
- Published
- 2023
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30. Wet adhesive hydrogels to correct malacic trachea (tracheomalacia) A proof of concept .
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Uslu E, Rana VK, Anagnostopoulos S, Karami P, Bergadano A, Courbon C, Gorostidi F, Sandu K, Stergiopulos N, and Pioletti DP
- Abstract
Tracheomalacia (TM) is a condition characterized by a weak tracheal cartilage and/or muscle, resulting in excessive collapse of the airway in the newborns. Current treatments including tracheal reconstruction, tracheoplasty, endo- and extra-luminal stents have limitations. To address these limitations, this work proposes a new strategy by wrapping an adhesive hydrogel patch around a malacic trachea. Through a numerical model, first it was demonstrated that a hydrogel patch with sufficient mechanical and adhesion strength can preserve the trachea's physiological shape. Accordingly, a new hydrogel providing robust adhesion on wet tracheal surfaces was synthesized employing the hydroxyethyl acrylamide (HEAam) and polyethylene glycol methacrylate (PEGDMA) as main polymer network and crosslinker, respectively. Ex vivo experiments revealed that the adhesive hydrogel patches can restrain the collapsing of malacic trachea under negative pressure. This study may open the possibility of using an adhesive hydrogel as a new approach in the difficult clinical situation of tracheomalacia., Competing Interests: The authors declare no competing interests., (© 2023 The Author(s).)
- Published
- 2023
- Full Text
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31. Feasibility study of the Nox-T3 device to detect swallowing and respiration pattern in neurologically impaired patients in the acute phase.
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Theytaz F, Vuistiner A, Schweizer V, Crépin A, Sandu K, Chaouch A, Piquilloud L, Lecciso G, Coombes K, and Diserens K
- Subjects
- Humans, Feasibility Studies, Respiration, Apnea, Deglutition, Deglutition Disorders diagnostic imaging
- Abstract
Dysphagia is a frequent complication in neurologically impaired patients, which can lead to aspiration pneumonia and thus prolonged hospitalization or even death. It is essential therefore, to detect and assess dysphagia early for best patient care. Fiberoptic endoscopic and Videofluoroscopy evaluation of swallowing are the gold standard exams in swallowing studies but neither are perfectly suitable for patients with disorders of consciousness (DOC). In this study, we aimed to find the sensitivity and specificity of the Nox-T3 sleep monitor for detection of swallowing. A combination of submental and peri-laryngeal surface electromyography, nasal cannulas and respiratory inductance plethysmography belts connected to Nox-T 3 allows recording swallowing events and their coordination with breathing, providing time-coordinated patterns of muscular and respiratory activity. We compared Nox-T3 swallowing capture to manual swallowing detection on fourteen DOC patients. The Nox-T3 method identified swallow events with a sensitivity of 95% and a specificity of 99%. In addition, Nox-T3 has qualitative contributions, such as visualization of the swallowing apnea in the respiratory cycle which provide additional information on the swallowing act that is useful to clinicians in the management and rehabilitation of the patient. These results suggest that Nox-T3 could be used for swallowing detection in DOC patients and support its continued clinical use for swallowing disorder investigation., (© 2023. The Author(s).)
- Published
- 2023
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32. Endoscopy-guided pharyngoesophageal stent fixation after total laryngectomy.
- Author
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Salati V, Sandu K, and Gorostidi F
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- Humans, Pharynx surgery, Endoscopy, Gastrointestinal, Laryngectomy, Laryngeal Neoplasms surgery
- Abstract
Competing Interests: The authors declare that they have no conflict of interest.
- Published
- 2022
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33. Pediatric vascular anomalies with airway compromise.
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Gorostidi F, Glasson N, Salati V, and Sandu K
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- Child, Female, Humans, Infant, Infant, Newborn, Pregnancy, Esthetics, Dental, Laryngostenosis, Prenatal Diagnosis adverse effects, Tracheotomy, Airway Obstruction etiology, Airway Obstruction surgery, Vascular Malformations
- Abstract
Vascular anomalies are rare lesions of diverse nature that may affect the head and neck region. Any mass in or around the upper airway has the potential to obstruct or compromise it. The absolute priority, before etiologic treatment, is the evaluation of the risk for the airway and its management. Prenatal diagnosis of an upper airway obstruction requires a planned delivery in a center having a specialized team experienced in managing a compromised feto-neonatal airway, and who could perform an ex-utero intrapartum treatment to secure the airway. Even after birth, the airway remains central in the patient's overall management. Signs and symptoms of airway compromise must be evaluated keeping in mind the specific requirements of infants and small children and being aware that rapid worsening may occur. The treatment is then tailored to the patient and his lesion with the goal of improving symptoms while avoiding treatment-related complications. Maintaining reasonable expectations by the patient and families are part of a successful management. Cure is achievable for small and localized lesions, but symptom relief and mitigation of functional, esthetic and psychological impairments is the goal for large and complex lesions. If a tracheotomy was required, decannulation is one of the primary management goals., (© 2022 The Authors. Journal of Oral Pathology & Medicine published by John Wiley & Sons Ltd.)
- Published
- 2022
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34. International Pediatric Otolaryngology Group (IPOG) consensus recommendations: Evaluation and management of congenital tracheal stenosis.
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Sidell DR, Meister KD, de Alarcon A, Boudewyns A, Brigger M, Chun R, Fayoux P, Goudy S, Hart CK, Hewitt R, Hsu WC, Javia LR, Johnson RF, Messner AH, Moreddu E, Nicollas R, Prager JD, Rahbar R, Rickert S, Rossi ME, Russell J, Rutter M, Sandu K, Smith RJH, Soma M, Thierry B, Trozzi M, White DR, and Balakrishnan K
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- Child, Consensus, Constriction, Pathologic, Humans, Infant, Trachea abnormalities, Trachea surgery, Tracheal Stenosis congenital, Treatment Outcome, Otolaryngology, Plastic Surgery Procedures methods
- Abstract
Objectives: To outline an expert-based consensus of recommendations for the diagnosis and management of pediatric patients with congenital tracheal stenosis., Methods: Expert opinions were sought from members of the International Pediatric Otolaryngology Group (IPOG) via completion of an 18-item survey utilizing an iterative Delphi method and review of the literature., Results: Forty-three members completed the survey providing recommendations regarding the initial history, clinical evaluation, diagnostic evaluation, temporizing measures, definitive repair, and post-repair care of children with congenital tracheal stenosis., Conclusion: These recommendations are intended to be used to support clinical decision-making regarding the evaluation and management of children with congenital tracheal stenosis. Responses highlight the diverse management strategies and the importance of a multidisciplinary approach to care of these patients., (Copyright © 2022 Elsevier B.V. All rights reserved.)
- Published
- 2022
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35. Early prediction of hospital outcomes in patients tracheostomized for complex mechanical ventilation weaning.
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Cabrio D, Vesin T, Lupieri E, Messet H, Sandu K, and Piquilloud L
- Abstract
Background: Tracheostomy is often performed in the intensive care unit (ICU) when mechanical ventilation (MV) weaning is prolonged to facilitate daily care. Tracheostomized patients require important healthcare resources and have poor long-term prognosis after the ICU. However, data lacks regarding prediction of outcomes at hospital discharge. We looked for patients' characteristics, ventilation parameters, sedation and analgesia use (pre-tracheostomy) that are associated with favorable and poor outcomes (post-tracheostomy) using univariate and multivariate logistic regressions., Results: Eighty tracheostomized patients were included (28.8% women, 60 [52-71] years). Twenty-three (28.8%) patients were intubated for neurological reasons. Time from intubation to tracheostomy was 14.7 [10-20] days. Thirty patients (37.5%) had poor outcome (19 patients deceased and 11 still tracheostomized at hospital discharge). All patients discharged with tracheostomy (n = 11) were initially intubated for a neurological reason. In univariate logistic regressions, older age and higher body-mass index (BMI) were associated with poor outcome (OR 1.18 [1.07-1.32] and 1.04 [1.01-1.08], p < 0.001 and p = 0.025). No MV parameters were associated with poor outcome. In the multiple logistic regression model higher BMI and older age were also associated with poor outcome (OR 1.21 [1.09-1.36] and 1.04 [1.00-1.09], p < 0.001 and p = 0.046)., Conclusions: Hospital mortality of patients tracheostomized because of complex MV weaning was high. Patients intubated for neurological reasons were frequently discharged from the acute care hospital with tracheostomy in place. Both in univariate and multivariate logistic regressions, only BMI and older age were associated with poor outcome after tracheostomy for patients undergoing prolonged MV weaning., (© 2022. The Author(s).)
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- 2022
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36. Moderate grade subglottic stenosis in children: Laryngotracheal reconstruction versus cricotracheal resection and anastomosis.
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Beatrix Christina Kokje V, Ishii A, and Sandu K
- Abstract
Objective: The surgical treatment of choice of pediatric moderate subglottic stenosis (major grade II and minor grade III SGS or 60-80% lumen obstruction) remains controversial. Laryngotracheal reconstruction (LTR) (with anterior ± posterior grafts for airway expansion) and partial crico-tracheal resection (PCTR) are the mainly described open surgical techniques. We reviewed our pediatric cases with moderate subglottic stenosis to determine the efficacy of LTR versus PCTR., Methods: A retrospective study of all children between 0 and 18 years that underwent open reconstructive airway surgery between 2012 and 2019. Children who had either acquired or congenital moderate subglottic stenosis (late grade II and early grade III: 60-80% lumen obstruction) were selected., Results: Twenty-six children with moderate-grade subglottic stenosis were included. Seventeen were treated with LTR and nine with PCTR. No significant differences were observed between LTR and PCTR-treated cases. Decannulation rates were similar, as well as the functional results., Conclusion: Both LTR and PCTR are valid treatment options for moderate subglottic stenosis. This study indicates to perform the surgery that is most suitable for the characteristics of the patients' stenosis, the surgeons' expertise and preference, and the working infrastructure., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Beatrix Christina Kokje, Ishii and Sandu.)
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- 2022
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37. Long-term results of slide laryngotracheoplasty for congenital subglottic stenosis in newborns and infants.
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Erdélyi E, Bach Á, Sztanó B, Gál P, Sandu K, Bereczki C, and Rovó L
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- Child, Humans, Infant, Infant, Newborn, Quality of Life, Reproducibility of Results, Laryngoplasty methods, Laryngostenosis congenital, Laryngostenosis surgery, Larynx
- Abstract
Objectives: Slide laryngotracheoplasty is an effective, single-step procedure without tracheostomy and stenting for treating high-grade congenital subglottic stenosis in neonates and infants. Long-term outcomes were evaluated to assess the reliability of the procedure performed in this age of rapid development of the laryngeal structures., Methods: We report five children who underwent slide laryngotracheoplasty before the age of 4 months, each with >3 years follow-up. Increases of length and bodyweight were systematically assessed. Breathing, swallowing, voice, and overall satisfaction was assessed by a quality of life questionnaire. Voice quality was objectively evaluated by measuring shimmer, jitter, fundamental frequency, and the harmonics-to-noise ratio., Results: All patients had a stable and adequate airway during follow-up without any additional open airway surgery. The patients' voices were physiological, and the intervention had no negative impact on speech development. Swallowing function was optimally retained, and the patients' bodyweight gain and length were satisfactory. During at least 3 years of observation, the anastomosis remained stable and grew dynamically with the patient., Conclusions: Slide laryngotracheoplasty (as a single-step procedure) provides an adequate airway without tracheostomy, grafting, or stenting with good long-term functional results in selected neonates and infants with congenital subglottic stenosis., (Copyright © 2022 Elsevier B.V. All rights reserved.)
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- 2022
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38. Novel Technique for Fixing Tracheal Stents.
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Salati V, Lovis A, Gonzalez M, Sandu K, and Gorostidi F
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- Bronchi, Humans, Stents, Trachea surgery, Airway Obstruction surgery, Tracheal Stenosis surgery
- Abstract
Endoscopic management of benign or malignant airway obstructions sometimes requires stenting after dilatation or debulking of the tumor. Straight stents are highly prone to migration in the trachea and the main bronchus, with potential catastrophic consequences. Multiple fixation strategies have been described to secure subglottic stents, each having certain limitations. This report describes a novel, "inside-to-outside" stent fixation in the upper airway using the Lichtenberger needle carrier in 2 consecutive patients., (Copyright © 2022 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.)
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- 2022
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39. Laryngotracheal Complications in Intubated COVID-19 Patients.
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Sandu K
- Abstract
During the current COVID-19 pandemic, several emerging cases of laryngotracheal stenosis following prolonged intubation and tracheostomy are being reported. The patients' pre-existing comorbidities, the disease itself and the pronation maneuvers increase the risk for endolaryngeal and tracheal damage. In this commentary, we report 4 such patients with acquired severe laryngotracheal stenosis. We describe their airway lesions, the surgical treatment they received, and the outcomes., Competing Interests: Declaration of conflicting interests:The author declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2021.)
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- 2021
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40. Intubation Related Laryngeal Injuries in Pediatric Population.
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Lambercy K, Pincet L, and Sandu K
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Introduction: Laryngeal intubation related lesions (LIRL) in pediatric patients cause extreme morbidity in both elective and emergency settings. It has a wide range of presentations from minor laryngeal edema to a life-threatening airway obstruction. We report here our units' experience with LIRL in neonates, infants, and small children. Material and Methods: This is a retrospective monocentric cohort study between January 2013 and April 2019. Results: Thirty-nine patients with intubation lesions were included in the study. We looked at the lesions type, characteristics, management, and outcome. Half the patients were premature and having comorbidities. Main LIRL were subglottic stenosis (31%), ulcers (26%), granulations (18%), retention cysts (18%), posterior glottic stenosis (13%), and vocal cords edema (5%). Unfavorable lesions causing airway stenosis were associated with an intubation duration of over 1 week and were an important factor in causing airway stenosis ( p < 0.05). The endoscopic treatment performed for these lesions was lesion and anatomical site-specific. Tracheostomy was needed in five patients, and was avoided in another two. Seven patients (18%) received open surgery prior to their decannulation. Conclusions: LIRL management is challenging and stressful in the pediatric population and optimal treatment could avoid extreme morbidity in them. Intubation duration and associated comorbidities are important factors in deciding the severity of these lesions. Protocols to prevent the formation of these lesions are critical., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Lambercy, Pincet and Sandu.)
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- 2021
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41. International Pediatric Otolaryngology Group (IPOG) management recommendations: Pediatric tracheostomy decannulation.
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Kennedy A, Hart CK, de Alarcon A, Balakrishnan K, Boudewyns A, Chun R, Fayoux P, Goudy SL, Hartnick C, Hsu WC, Johnson RF, Kuo M, Peer S, Pransky SM, Rahbar R, Rickert S, Roy S, Russell J, Sandu K, Sidell DR, Smith RJ, Soma M, Spratley J, Thierry B, Thompson DM, Trozzi M, Watters K, White DR, Wyatt M, Zalzal GH, Zdanksi CJ, Zur KB, and Rutter MJ
- Subjects
- Child, Device Removal, Humans, Infant, Patient-Centered Care, Retrospective Studies, Otolaryngology, Tracheostomy
- Abstract
Objectives: To provide recommendations to otolaryngologists, pulmonologists, and allied clinicians for tracheostomy decannulation in pediatric patients., Methods: An iterative questionnaire was used to establish expert recommendations by the members of the International Pediatric Otolaryngology Group., Results: Twenty-six members completed the survey. Recommendations address patient criteria for decannulation readiness, airway evaluation prior to decannulation, decannulation protocol, and follow-up after both successful and failed decannulation., Conclusion: Tracheostomy decannulation recommendations are aimed at improving patient-centered care, quality and safety in children with tracheostomies., (Copyright © 2020 Elsevier B.V. All rights reserved.)
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- 2021
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42. Long-term intubation and high rate of tracheostomy in COVID-19 patients might determine an unprecedented increase of airway stenoses: a call to action from the European Laryngological Society.
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Piazza C, Filauro M, Dikkers FG, Nouraei SAR, Sandu K, Sittel C, Amin MR, Campos G, Eckel HE, and Peretti G
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- COVID-19 diagnosis, Constriction, Pathologic etiology, Female, Humans, Intensive Care Units, Intubation, Intratracheal adverse effects, Male, Otolaryngologists, Otolaryngology, Pandemics, SARS-CoV-2, Societies, Medical, Tracheostomy adverse effects, Airway Management methods, COVID-19 therapy, Intubation, Intratracheal statistics & numerical data, Laryngostenosis epidemiology, Respiration, Artificial adverse effects, Tracheal Stenosis epidemiology, Tracheostomy statistics & numerical data
- Abstract
Introduction: The novel Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2, may need intensive care unit (ICU) admission in up to 12% of all positive cases for massive interstitial pneumonia, with possible long-term endotracheal intubation for mechanical ventilation and subsequent tracheostomy. The most common airway-related complications of such ICU maneuvers are laryngotracheal granulomas, webs, stenosis, malacia and, less commonly, tracheal necrosis with tracheo-esophageal or tracheo-arterial fistulae., Materials and Methods: This paper gathers the opinions of experts of the Laryngotracheal Stenosis Committee of the European Laryngological Society, with the aim of alerting the medical community about the possible rise in number of COVID-19-related laryngotracheal stenosis (LTS), and the aspiration of paving the way to a more rationale concentration of these cases within referral specialist airway centers., Results: A range of prevention strategies, diagnostic work-up, and therapeutic approaches are reported and framed within the COVID-19 pandemic context., Conclusions: One of the most important roles of otolaryngologists when encountering airway-related signs and symptoms in patients with previous ICU hospitalization for COVID-19 is to maintain a high level of suspicion for LTS development, and share it with colleagues and other health care professionals. Such a condition requires specific expertise and should be comprehensively managed in tertiary referral centers.
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- 2021
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43. International Pediatric Otolaryngology Group (IPOG) consensus recommendations: Management of suprastomal collapse in the pediatric population.
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Doody J, Alkhateeb A, Balakrishnan K, Bedwell J, Carter J, Choi SS, Cheng AT, Daniel SJ, Dahl J, De Alarcon A, Fayoux P, Hart CK, Hartnick C, Jonas N, Kuo M, Mills N, Muntz H, Nicollas R, Pransky S, Nuss R, Propst EJ, Rahbar R, Rossi ME, Rutter MJ, Sandu K, Sidell DR, Sittel C, Smith RJH, Soma M, Spratley J, Thierry B, Thompson D, Watters K, Wine T, Wyatt M, Zalzal G, Zdanski CJ, Zur KB, and Russell J
- Subjects
- Child, Consensus, Humans, Infant, Otolaryngology, Tracheostomy adverse effects
- Abstract
Introduction: Suprastomal Collapse (SuStCo) is a common complication of prolonged tracheostomy in children. There is a paucity of literature on this subject, especially regarding how to manage significant suprastomal collapse that prevents safe decannulation., Objective: Provide a definition, classification system, and recommend management options for significant suprastomal collapse in children with tracheostomy., Methods: Members of the International Pediatric Otolaryngology Group (IPOG) who are experts in pediatric airway conditions were surveyed and results were refined using a modified Delphi method., Results: Consensus was defined as > 70% agreement on a subject. The experts achieved consensus: CONCLUSION: This consensus statement provides recommendations for medical specialists who manage infants and children with tracheostomies with significant Suprastomal Collapse. It provides a classification system to facilitate diagnosis and treatment options for this condition., (Copyright © 2020 Elsevier B.V. All rights reserved.)
- Published
- 2020
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44. [Laryngeal reinnervation].
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Salati V, Beharry A, Fries S, Sandu K, and Gorostidi F
- Subjects
- Humans, Prospective Studies, Larynx surgery, Recurrent Laryngeal Nerve surgery, Vocal Cord Paralysis surgery, Vocal Cords surgery
- Abstract
The surgical management of unilateral and bilateral vocal cord paralysis depends on the severity of the condition, the potential for spontaneous recovery, the patient's age and vocal expectations. Standardized re-innervation surgeries, unilateral non-selective and bilateral selective, are viable alternatives to static procedures currently under evaluation in prospective studies. Neurorraphy of the ansa cervicalis loop to the recurrent laryngeal nerve allows lasting vocal recovery and potentially superior results to medialization and thyroplasty, by maintaining the visco-elastic properties of the vocal cord and preventing its atrophy. Selective bilateral reinnervation shows potential for recovery of inspiratory abduction with improved respiratory function without vocal deterioration., Competing Interests: Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article.
- Published
- 2020
45. Outcomes of balloon dilation for paediatric laryngeal stenosis.
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Cantarella G, Gaffuri M, Torretta S, Neri S, Ambrosini MT, D'Onghia A, Pignataro L, and Sandu K
- Subjects
- Adult, Child, Dilatation, Humans, Retrospective Studies, Treatment Outcome, Laryngoplasty, Laryngostenosis surgery
- Abstract
Objective: Balloon dilation (BD) is a minimally invasive endoscopic treatment for paediatric laryngeal stenosis (LS) with reduced morbidity compared to open surgery. We retrospectively describe our experience in a cohort of children with chronic LS., Methods: Fourteen children (median age: 28.5; range: 2-81 months) with chronic LS (multilevel in 8) were treated with tubeless total intravenous anaesthesia under spontaneous ventilation., Results: Grade III LS was preoperatively detected in 12 children; the remaining 2 had grade IV stenosis. Six had prior tracheotomy, and one received it during the first intervention. Dilation laryngoplasty was the primary treatment in 11 children and was used as an adjuvant treatment in 3 after open reconstructive surgery. The median number of dilations was 2 (range: 1-6). There were no postoperative complications. At the end of the follow-up (median: 20.5; range: 2-46 months), detectable laryngeal lumen widening and/or respiratory improvement occurred in 12 children. Two of 7 patients with tracheostomy were decannulated., Conclusions: Balloon laryngoplasty is a valuable therapeutic option to improve laryngeal patency in children with chronic multilevel LS, both as a primary and secondary adjuvant treatment after reconstructive surgery., (Copyright © 2020 Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale, Rome, Italy.)
- Published
- 2020
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46. Slide laryngotracheoplasty for congenital subglottic stenosis in newborns and infants.
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Rovó L, Erdélyi E, Tóbiás Z, Gál P, Szegesdi I, Sztanó B, Sandu K, and Bach Á
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- Female, Humans, Infant, Infant, Newborn, Intubation, Intratracheal, Laryngoscopy, Laryngostenosis diagnostic imaging, Magnetic Resonance Imaging, Male, Phonation, Quality of Life, Surveys and Questionnaires, Tomography, X-Ray Computed, Laryngostenosis congenital, Laryngostenosis surgery
- Abstract
Objectives: Subglottic stenosis is the most common laryngeal anomaly necessitating tracheostomy in early childhood. Crico- and laryngotracheal resection and laryngotracheal reconstruction-usually with autologous cartilage graft implantation-are the most effective treatments. These surgical techniques are obviously challenging in neonatal age and infancy. However, a reconstructive surgery performed at early age may prevent the sequel of complications., Methods: The authors present their novel surgical method for congenital subglottic stenosis. Seven infants had inspiratory stridor; two of them had to be intubated and one required tracheostomy. Laryngotracheoscopy, CT or MRI revealed subglottic stenosis: Cotton-Myer grade II in one, and grade III in six cases. Slide laryngotracheoplasty was performed before 5 months of age (10-130 days), with a follow-up period of average 36 months (4-80 months). Phoniatry and quality of life questionnaire were used for evaluation of postoperative results., Results: Slide laryngotracheoplasty in the neonatal age made the temporary tracheostomy unnecessary. All babies remained intubated for 3 to 10 days with an uncuffed tracheal tube. After extubation, no dyspnea or swallowing disorder occurred. A subjective quality of life questionnaire, laryngotracheoscopy, clinical growth charts showed satisfactory functional results., Conclusions: Single-stage slide laryngotracheoplasty might be a favorable solution for subglottic stenosis, even in early childhood. In one step, the airway can be maintained without stenting and tracheostomy., Level of Evidence: 4 Laryngoscope, 130:E199-E205, 2020., (© 2019 The American Laryngological, Rhinological and Otological Society, Inc.)
- Published
- 2020
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47. [Congenital tracheal stenosis: from clinic to treatment.]
- Author
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Duchoud L, De Sandre-Mouly C, and Sandu K
- Subjects
- Airway Obstruction, Constriction, Pathologic diagnosis, Humans, Trachea surgery, Tracheal Stenosis congenital, Tracheal Stenosis diagnosis, Tracheal Stenosis surgery, Constriction, Pathologic congenital, Constriction, Pathologic surgery, Trachea abnormalities
- Abstract
Congenital tracheal stenosis is a rare malformation of the fibrino-cartilaginous tracheal skeleton, frequently associated with cardiac malformations. The symptoms and the age of presentation varie according to the severity of the stenosis. There is a risk of airway obstruction. The diagnosis is based on endoscopy and surgery is usually required., Competing Interests: Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article.
- Published
- 2019
48. Role of Unilateral Vocal Cord Palsy in Causing Recurrent Tracheobronchial Foreign Bodies.
- Author
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Pincet L, Lambercy K, and Sandu K
- Abstract
Background: Foreign body (FB) aspiration in children is a frequent condition managed by ENT pediatric surgeons and pediatric pulmonologists. Methods: We present the case of a 20-months-old child who presented with three recurrent episodes of FB aspiration. Results: At the time of FB removal, an initial dynamic examination of the larynx revealed a unilateral vocal cord palsy (UVCP). Conclusion: For recurrent tracheobronchial FB inhalation, we recommend a systematic dynamic airway endoscopy.
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- 2019
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49. Combined use of Ventrain and S-Guide for Airway Management of Severe Subglottic Stenosis.
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Zuercher M, Pythoud-Brügger M, Sandu K, and Schoettker P
- Abstract
The airway management of a patient with severe tracheal stenosis depends on its severity, length, location, and type of surgery. Its management is complex and requires the collaboration of an experienced team of anaesthetist and ear, nose, and throat surgeon. We report an innovative combination of Ventrain™ and S-Guide™ for airway management of a planned endoscopic dilation of a severe subglottic stenosis in an adult patient. This new alternative may offer advantages over existing airway management techniques in similar cases., Competing Interests: Conflict of Interest: The authors have no conflicts of interest to declare.
- Published
- 2019
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50. Transoral robotic-assisted supracricoid partial laryngectomy with cricohyoidoepiglottopexy: Procedure development and outcomes of initial cases.
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Morisod B, Guinchard AC, Gorphe P, Schweizer V, Sandu K, and Simon C
- Subjects
- Aged, Carcinoma, Squamous Cell surgery, Deglutition, Feasibility Studies, Female, Historically Controlled Study, Humans, Male, Middle Aged, Quality of Life, Voice Quality, Cricoid Cartilage surgery, Epiglottis surgery, Hyoid Bone surgery, Laryngeal Neoplasms surgery, Laryngectomy methods, Robotic Surgical Procedures methods
- Abstract
Background: We report on the feasibility and functional outcome of transoral robotic (TORS) supracricoid partial laryngectomy (SCPL) with cricohyoidoepiglottopexy (CHEP)., Methods: Cadaveric studies and functional outcome at 3 years using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ-H&N35), the Functional Outcome Swallowing Scale (FOSS), the Performance Status Scale for Head and Neck Cancer (PSS-HN), computerized voice analysis, and videotape recordings. Data were compared with a historical cohort of open CHEPs/cricohyoidopexies (CHPs)., Results: The EORTC-QLQ-H&N35 scores, FOSS scores, and PSS-HN scores at 3 years of 2 operated patients were 46 and 43, 2 and 1, and 75 of 100 (eating in public) and 100 of 100 (normalcy of diet), respectively. The mean fundamental frequency, jitter, shimmer, noise-to-harmonic ratio (NHR), and maximum phonation time (MPT) were 85 HZ and 81 Hz, 8.52% and 6.39%, 28.2% and 13.5%, 0.61 and 0.71, 19 seconds and 15 seconds, respectively., Conclusion: Functional outcome data suggest that the procedure is feasible and safe., (© 2018 Wiley Periodicals, Inc.)
- Published
- 2018
- Full Text
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