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3. Age‐related decline in urine concentration may not be universal: Comparative study from the U.S. and two small‐scale societies

Author

Rosinger, Asher Y, Pontzer, Herman, Raichlen, David A, Wood, Brian M, Tanner, Susan N, and Sands, Jeff M

Subjects
Biological Sciences, Ecology, History, Heritage and Archaeology, Human Society, Archaeology, Anthropology, Kidney Disease, Clinical Research, Prevention, Aging, Nutrition, Adolescent, Adult, Aged, Aged, 80 and over, Biomarkers, Bolivia, Female, Humans, Kidney, Kidney Diseases, Life Style, Male, Middle Aged, Tanzania, United States, Urinalysis, Young Adult, aging, kidney physiology, lifestyle mismatch, urine concentration, Evolutionary Biology
Abstract

OBJECTIVES:Evidence from industrialized populations suggests that urine concentrating ability declines with age. However, lifestyle factors including episodic protein intake and low hypertension may help explain differences between populations. Whether this age-related decline occurs among small-scale populations with active lifestyles and non-Western diets is unknown. We test the universality of age-related urine concentration decline. MATERIALS AND METHODS:We used urine specific gravity (Usg) and urine osmolality (Uosm) data from 15,055 U.S. nonpregnant adults without kidney failure aged 18-80 in 2007-2012 participating in the National Health and Nutrition Examination Survey (NHANES). We tested the relationship of age on urine concentration biomarkers with multiple linear regressions using survey commands. We compared results to longitudinal data on Usg from 116 Tsimane' forager-horticulturalists (266 observations) adults aged 18-83 in 2013-2014 from Lowland Bolivia, and to 38 Hadza hunter-gatherers (156 observations) aged 18-75 in 2010-2015 from Tanzania using random-effects panel linear regressions. RESULTS:Among U.S. adults, age was significantly negatively associated with Usg (Adjusted beta [B] = -0.0009 g/mL/10 years; SE = 0.0001; p

Published
2019

5. Renoprotective Effects of Daprodustat in Patients with Chronic Kidney Disease and Renal Anemia.

Author

Shimada, Yoshitaka, Izumi, Yuichiro, Yasuoka, Yukiko, Oshima, Tomomi, Nagaba, Yasushi, Nanami, Masayoshi, Sands, Jeff M., Takahashi, Noriko, Kawahara, Katsumasa, and Nonoguchi, Hiroshi

Abstract

Many large-scale studies revealed that exogenous erythropoietin, erythropoiesis-stimulating agents, have no renoprotective effects. We reported the renoprotective effects of endogenous erythropoietin production on renal function in ischemic reperfusion injury (IRI) of the kidney using the prolyl hydroxylase domain (PHD) inhibitor, Roxadustat. The purpose of this study was to investigate the effects of daprodustat on the progression of chronic renal failure. We retrospectively investigated the effects of daprodustat on the progression of chronic renal failure and renal anemia in patients with stages 3a-5 chronic kidney diseases (estimated glomerular filtration rate, eGFR < 60 mL/min/1.73 m2). The results show that daprodustat largely slowed the reduction in eGFR. The recovery of renal function was observed in some patients. Daprodustat is useful not only for renal anemia but also for the preservation of renal function. The renoprotective effect of daprodustat was small in patients with serum creatinine larger than 3–4 mg/dL because of low residual renal function. The appearance of renal anemia would be a sign of the time to start using daprodustat. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Tubular Endogenous Erythropoietin Protects Renal Function against Ischemic Reperfusion Injury

Author

Yasuoka, Yukiko, primary, Izumi, Yuichiro, additional, Fukuyama, Takashi, additional, Oshima, Tomomi, additional, Yamazaki, Taiga, additional, Uematsu, Takayuki, additional, Kobayashi, Noritada, additional, Nanami, Masayoshi, additional, Shimada, Yoshitaka, additional, Nagaba, Yasushi, additional, Mukoyama, Masashi, additional, Sands, Jeff M., additional, Takahashi, Noriko, additional, Kawahara, Katsumasa, additional, and Nonoguchi, Hiroshi, additional

Published
2024
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8. Imaging Renal Urea Handling in Rats at Millimeter Resolution using Hyperpolarized Magnetic Resonance Relaxometry

Author

Reed, Galen D., von Morze, Cornelius, Verkman, Alan S., Koelsch, Bertram L., Chaumeil, Myriam M., Lustig, Michael, Ronen, Sabrina M., Sands, Jeff M., Larson, Peder E. Z., Wang, Zhen J., Larsen, Jan Henrik Ardenkjær, Kurhanewicz, John, and Vigneron, Daniel B.

Subjects
Physics - Medical Physics, Physics - Biological Physics, Quantitative Biology - Tissues and Organs
Abstract

\textit{In vivo} spin spin relaxation time ($T_2$) heterogeneity of hyperpolarized \textsuperscript{13}C urea in the rat kidney was investigated. Selective quenching of the vascular hyperpolarized \textsuperscript{13}C signal with a macromolecular relaxation agent revealed that a long-$T_2$ component of the \textsuperscript{13}C urea signal originated from the renal extravascular space, thus allowing the vascular and renal filtrate contrast agent pools of the \textsuperscript{13}C urea to be distinguished via multi-exponential analysis. The $T_2$ response to induced diuresis and antidiuresis was performed with two imaging agents: hyperpolarized \textsuperscript{13}C urea and a control agent hyperpolarized bis-1,1-(hydroxymethyl)-1-\textsuperscript{13}C-cyclopropane-$^2\textrm{H}_8$. Large $T_2$ increases in the inner-medullar and papilla were observed with the former agent and not the latter during antidiuresis suggesting that $T_2$ relaxometry may be used to monitor the inner-medullary urea transporter (UT)-A1 and UT-A3 mediated urea concentrating process. Two high resolution imaging techniques - multiple echo time averaging and ultra-long echo time sub-2 mm$^3$ resolution 3D imaging - were developed to exploit the particularly long relaxation times observed.

Published
2015

11. Imaging Renal Urea Handling in Rats at Millimeter Resolution Using Hyperpolarized Magnetic Resonance Relaxometry

Author

Reed, Galen D, von Morze, Cornelius, Verkman, Alan S, Koelsch, Bertram L, Chaumeil, Myriam M, Lustig, Michael, Ronen, Sabrina M, Bok, Robert A, Sands, Jeff M, Larson, Peder EZ, Wang, Zhen J, Larsen, Jan Henrik Ardenkjær, Kurhanewicz, John, and Vigneron, Daniel B

Subjects
Medical Physiology, Biomedical and Clinical Sciences, Chemical Sciences, Kidney Disease, urea, dynamic nuclear polarization, NMR relaxation, transporter, physics.med-ph, physics.bio-ph, q-bio.TO
Abstract

In vivo spin spin relaxation time (T2) heterogeneity of hyperpolarized [13C,15N2]urea in the rat kidney was investigated. Selective quenching of the vascular hyperpolarized 13C signal with a macromolecular relaxation agent revealed that a long-T2 component of the [13C,15N2]urea signal originated from the renal extravascular space, thus allowing the vascular and renal filtrate contrast agent pools of the [13C,15N2]urea to be distinguished via multi-exponential analysis. The T2 response to induced diuresis and antidiuresis was performed with two imaging agents: hyperpolarized [13C,15N2]urea and a control agent hyperpolarized bis-1,1-(hydroxymethyl)-1-13C-cyclopropane-2H8. Large T2 increases in the inner-medullar and papilla were observed with the former agent and not the latter during antidiuresis. Therefore, [13C,15N2]urea relaxometry is sensitive to two steps of the renal urea handling process: glomerular filtration and the inner-medullary urea transporter (UT)-A1 and UT-A3 mediated urea concentrating process. Simple motion correction and subspace denoising algorithms are presented to aid in the multi exponential data analysis. Furthermore, a T2-edited, ultra long echo time sequence was developed for sub-2 mm3 resolution 3D encoding of urea by exploiting relaxation differences in the vascular and filtrate pools.

Published
2016

12. Tubular Endogenous Erythropoietin Protects Renal Function against Ischemic Reperfusion Injury

Author

Yasuoka, Yukiko, primary, Izumi, Yuichiro, additional, Fukuyama, Takashi, additional, Oshima, Tomomi, additional, Yamazaki, Taiga, additional, Uematsu, Takayuki, additional, Kobayashi, Noritada, additional, Nanami, Masayoshi, additional, Shimada, Yoshitaka, additional, Nagaba, Yasushi, additional, Mukoyama, Masashi, additional, Sands, Jeff M, additional, Takahashi, Noriko, additional, Kawahara, Katsumasa, additional, and Nonoguchi, Hiroshi, additional

Published
2023
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17. List of Contributors

Author

Abramovitz, Blaise, primary, Adu, Dwomoa, additional, Afshinnia, Farsad, additional, Agarwal, Anupam, additional, Andrews, Sarah C., additional, Appel, Gerald, additional, Bailey, James L., additional, Bakris, George L., additional, Bauer, Carolyn A., additional, Baxi, Pravir V., additional, Berns, Jeffrey S., additional, Birks, Peter, additional, Bomback, Andrew, additional, Bose, Anirban, additional, Brosius, Frank C., additional, Brown, Lee K., additional, Bushinsky, David A., additional, Busse, Laurence W., additional, Campbell, Ruth C., additional, Canney, Mark, additional, Cathro, Helen, additional, Chávez-Iñiguez, Jonathan, additional, Chawla, Lakhmir S., additional, Chen, Sheldon, additional, Chertow, Glenn M., additional, Chew, Emily Y., additional, Chonchol, Michel, additional, Clegg, Deborah J., additional, Clive, David M., additional, Clive, Pia H., additional, Cohen, Scott D., additional, Collins, Ashte' K., additional, Cooper, James E., additional, Correa-Rotter, Ricardo, additional, Cukor, Daniel, additional, Dalal, Monica, additional, Davenport, Andrew, additional, Davis, Scott, additional, Davison, Sara N., additional, Delanaye, Pierre, additional, de Zeeuw, Dick, additional, Dobre, Mirela A., additional, Drawz, Paul, additional, Ebert, Natalie, additional, Eggers, Paul, additional, Ferrè, Silvia, additional, Freedman, Barry I., additional, Furth, Susan L., additional, Gao, Bixia, additional, García-García, Guillermo, additional, Gashti, Casey N., additional, Germino, Gregory G., additional, Goldsmith, David, additional, Golestaneh, Ladan, additional, Goligorsky, Michael S., additional, Greenberg, Arthur, additional, Gregg, L. Parker, additional, Guay-Woodford, Lisa M., additional, Hamm, Lee, additional, Hart, Allyson, additional, Haselby, Danielle, additional, Hedayati, S. Susan, additional, Heerspink, Hiddo J.L., additional, Herzog, Charles A., additional, Hostetter, Thomas H., additional, House, Andrew A., additional, Hruska, Keith A., additional, Ishani, Areef, additional, Isom, Robert T., additional, James, Matthew T., additional, Jhaveri, Kenar D., additional, Johansen, Kirsten, additional, Johnson, Richard J., additional, Kang, Duk-Hee, additional, Kanno, Hiroko, additional, Kanno, Yoshihiko, additional, Karambelkar, Amrita D., additional, Karet Frankl, Fiona E., additional, Khoury, Charbel C., additional, Kimmel, Paul L., additional, Kopp, Jeffrey B., additional, Korbet, Stephen M., additional, Kruzel-Davila, Etty, additional, Kummer, Andrew, additional, LaFave, Laura, additional, Lakkis, Jay I., additional, Lerman, Lilach O., additional, Levin, Adeera, additional, Lew, Susie Q., additional, Luyckx, Valerie A., additional, Mattoo, Tej K., additional, Maynard, Sharon E., additional, McCullough, Peter A., additional, Mehrotra, Rajnish, additional, Meyer, Timothy W., additional, Mitch, William E., additional, Moe, Orson W., additional, Mohandes, Samer, additional, Moss, Alvin H., additional, Moxey-Mims, Marva, additional, Murugapandian, Sangeetha, additional, Nath, Karl A., additional, Neugarten, Joel, additional, Neyra, Javier A., additional, Nissenson, Allen R., additional, Nobakht, Ehsan, additional, Nolin, Thomas D., additional, Norris, Keith C., additional, Norton, Jenna M., additional, Nowak, Kristen L., additional, Ojo, Akinlolu O., additional, Pahl, Madeleine V., additional, Paller, Mark S., additional, Palmer, Biff F., additional, Palmer, Nicholette D., additional, Patel, Samir S., additional, Pecoits-Filho, Roberto, additional, Peitzman, Steven J., additional, Peixoto, Aldo J., additional, Pham, Phuong-Thu T., additional, Pham, Phuong-Chi T., additional, Piraino, Beth, additional, Pisoni, Roberto, additional, Rabelink, Ton, additional, Radhakrishnan, Jai, additional, Rahman, Mahboob, additional, Raj, Dominic S., additional, Ramírez-Sandoval, Juan C., additional, Rangaswami, Janani, additional, Reckelhoff, Jane F., additional, Regunathan-Shenk, Renu, additional, Reule, Scott, additional, Ronco, Claudio, additional, Rosenberg, Mark E., additional, Rosner, Mitchell H., additional, Rovin, Brad, additional, Roy-Chaudhury, Prabir, additional, Ruebner, Rebecca, additional, Rule, Andrew D., additional, Sands, Jeff M., additional, Schlanger, Lynn E., additional, Schrauben, Sarah J., additional, Seliger, Stephen, additional, Shah, Maulin, additional, Sterns, Richard H., additional, Stites, Erik, additional, Sugatani, Toshifumi, additional, Textor, Stephen C., additional, Thadhani, Ravi, additional, Thajudeen, Bijin, additional, Thakar, Surabhi, additional, Thomas, George, additional, Townsend, Raymond R., additional, Turner, Jeffrey, additional, Unruh, Mark L., additional, Urquhart, Bradley L., additional, Vassalotti, Joseph A., additional, Vaziri, Nosratola D., additional, Velasquez, Manuel T., additional, Ver Halen, Nisha, additional, Waddy, Salina P., additional, Wang, Jinwei, additional, Weber, Marc, additional, Weir, Matthew R., additional, White, Christine A., additional, Whittier, William L., additional, Williams, Matthew J., additional, Wiseman, Alexander C., additional, Wymer, David C., additional, Wymer, David T.G., additional, Yee, Jerry, additional, Zhang, Luxia, additional, Zhuang, Shougang, additional, and Ziyadeh, Fuad N., additional

Published
2020
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28. High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation

Author

Kitada, Kento, Daub, Steffen, Zhang, Yahua, Klein, Janet D., Nakano, Daisuke, Pedchenko, Tetyana, Lantier, Louise, LaRocque, Lauren M., Marton, Adriana, Neuber, Patrick, Schroder, Agnes, Rakova, Natalia, Jantsch, Jonathan, Dikalova, Anna E., Dikalov, Sergey I., Harrison, David G., Muller, Dominik N., Nishiyama, Akira, Rauh, Manfred, Harris, Raymond C., Luft, Friedrich C., Wassermann, David H., Sands, Jeff M., and Titze, Jens

Subjects
Energy metabolism -- Research, Salt (Food) -- Research, Water conservation -- Research, Body fluid osmolality -- Research, Health care industry
Abstract

Natriuretic regulation of extracellular fluid volume homeostasis includes suppression of the renin-angiotensin-aldosterone system, pressure natriuresis, and reduced renal nerve activity, actions that concomitantly increase urinary [Na.sup.+] excretion and lead to increased urine volume. The resulting natriuresis-driven diuretic water loss is assumed to control the extracellular volume. Here, we have demonstrated that urine concentration, and therefore regulation of water conservation, is an important control system for urine formation and extracellular volume homeostasis in mice and humans across various levels of salt intake. We observed that the renal concentration mechanism couples natriuresis with correspondent renal water reabsorption, limits natriuretic osmotic diuresis, and results in concurrent extracellular volume conservation and concentration of salt excreted into urine. This water-conserving mechanism of dietary salt excretion relies on urea transporter-driven urea recycling by the kidneys and on urea production by liver and skeletal muscle. The energy-intense nature of hepatic and extrahepatic urea osmolyte production for renal water conservation requires reprioritization of energy and substrate metabolism in liver and skeletal muscle, resulting in hepatic ketogenesis and glucocorticoid- driven muscle catabolism, which are prevented by increasing food intake. This natriuretic-ureotelic, water-conserving principle relies on metabolism-driven extracellular volume control and is regulated by concerted liver, muscle, and renal actions., Introduction Renal excretion of dietary [Na.sup.+] under high-salt conditions occurs by a natriuretic principle. The assumption is that high salt intake triggers thirst and thereby increases fluid intake, which expands [...]

Published
2017
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31. List of Contributors

Author

Adler, Gail K., primary, Ananth Karumanchi, S., additional, Ayoob, Rose, additional, Ayus, Juan C., additional, Bakris, George, additional, Baudrand, Rene, additional, Berl, Tomas, additional, Bollag, Wendy B., additional, Brines, Michael, additional, Brown, Alex J., additional, Brown, Ronald B., additional, Burnett Jr., John C., additional, Carey, Robert M., additional, Catanzaro, Daniel F., additional, Chauhan, Veeraish, additional, Chen, Yang, additional, Dusso, Adriana S., additional, Ecelbarger, Carolyn M., additional, Ferrario, Carlos M., additional, Friedman, Peter A., additional, Garg, Rajesh, additional, Gomez-Sanchez, Celso E., additional, Gomez-Sanchez, Elise P., additional, Gotoh, Koro, additional, Isales, Carlos M., additional, Kalim, Sahir, additional, Ko, Benjamin, additional, Kraut, Jeffrey A., additional, Macdougall, Iain C., additional, Mahan, John D., additional, Meems, Laura, additional, Menard, Joel, additional, Mihailidou, Anastasia S., additional, Mole, David R., additional, Monticone, Silvia, additional, Moritz, Michael L., additional, Nagami, Glenn T., additional, Nigwekar, Sagar U., additional, Padia, Shetal H., additional, Palmer, Biff F., additional, Parashar, Akhil, additional, Pojoga, Luminita, additional, Rainey, William E., additional, Ratcliffe, Peter J., additional, Razzaque, Mohammed S., additional, Rhee, Connie M., additional, Romero, Jose R., additional, Sands, Jeff M., additional, Schlanger, Lynn E., additional, Schrier, Robert W., additional, Shibata, Hirotaka, additional, Sica, Domenic A., additional, Simonson, Donald C., additional, Singh, Ajay K., additional, Sud, Karan, additional, Tiwari, Swasti, additional, Trask, Aaron J., additional, and Vilardaga, Jean-Pierre, additional

Published
2017
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36. Effects of Roxadustat on Erythropoietin Production in the Rat Body

Author

Yasuoka, Yukiko, primary, Izumi, Yuichiro, additional, Fukuyama, Takashi, additional, Omiya, Haruki, additional, Pham, Truyen D., additional, Inoue, Hideki, additional, Oshima, Tomomi, additional, Yamazaki, Taiga, additional, Uematsu, Takayuki, additional, Kobayashi, Noritada, additional, Shimada, Yoshitaka, additional, Nagaba, Yasushi, additional, Yamashita, Tetsuro, additional, Mukoyama, Masashi, additional, Sato, Yuichi, additional, Wall, Susan M., additional, Sands, Jeff M., additional, Takahashi, Noriko, additional, Kawahara, Katsumasa, additional, and Nonoguchi, Hiroshi, additional

Published
2022
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38. Contributors

Author

Adler, Sharon, Agarwal, Anupam, Agarwal, Rajiv, Aiyagari, Venkatesh, Alberton, Valeria, Anand, Shuchi, Arogundade, Fatiu, Arroyo, Vicente, Ash, Stephen R., Auguste, Bourne, Bailey, Matthew A., Bakris, George L., Bansal, Anip, Bargman, Joanne M., Barlow, Adam D., Barratt, Jonathan, Barsoum, Rashad S., Beaubien-Souligny, William, Beck, Laurence H., Jr, Bello, Aminu K., Benigni, Ariela, Berl, Tomas, Bircher, Gemma, Bockenhauer, Detlef, Boor, Peter, Bouchard, Josée, Bramham, Kate, Bridoux, Frank, Brown, Edwina, Brown, Mark, Burdmann, Emmanuel A., Bushinsky, David A., Cara-Fuentes, Gabriel, Cervelli, Matthew, Chadban, Steven James, Chan, Christopher, Chan, Christopher T., Chan, Melanie M.Y., Chapman, Jeremy R., Charlton, Karen, Chen, Wei, Cherney, David Z., Chua, Annabelle, Cohen-Stein, Debbie, Connolly, John O., Cook, Terence, Cooper, James, D’Agati, Vivette D., Damm, Tiffany L., Davies, Simon J., Davis, Scott, de Boer, Ian H., De Vriese, An S., Derman, Wayne, Drekonja, Dimitri M., Eckardt, Kai-Uwe, Elger, Marlies, Elliott, William J., Ellison, David H., Emmett, Michael, Evenepoel, Pieter, Falk, Ronald J., Fayed, Tarek S., Fermand, Jean-Paul, Fernandez, Javier, Fervenza, Fernando C., Fishbein, Lauren, Fisher, Molly, Floege, Jürgen, Fogazzi, Giovanni B., Foreman, John W., Free, Meghan, Gallagher, Kevin M., Garcia-Trabanino, Ramon, Garigali, Giuseppe, Georgianos, Panagiotis I., Girndt, Matthias, Glassock, Richard, Gorelick, Philip B., Grams, Morgan, Greco, Barbara Ann, Griffith, Megan, Guay-Woodford, Lisa Marie, Harris, Peter C., Heine, Gunnar Henrik, Herzog, Charles A., Hildebrandt, Friedhelm, Harmon, William E., Hooton, Thomas, Houillier, Pascal, Hughes, Jeremy, Inker, Lesley A., Irish, Ashley B., Jain, Koyal, Jefferson, Jonathan Ashley, Jennette, John Charles, Jha, Vivek, Johnson, Richard J., Wilshire Jones, Erika Sherad, Jones, Terry, Judd, Eric, Juncos, Luis A., Kalantar-Zadeh, Kamyar, Kalantari, Kambiz, Kanagasundaram, Nigel Suren, Kanellis, John, Karakala, Nithin, Kashkouli, Ali, Kashtan, Clifford E., Kauffman, Carol A., Kennedy, Claire, Kerr, Peter G., Kestenbaum, Bryan, Ketteler, Markus, Kopp, Jeffrey Burnett, Koratala, Abhilash, Kotanko, Peter, Kriz, Wilhelm, Kuhlmann, Martin K., Kumar, Reeti, Kuypers, Dirk R., Leung, Nelson, Levey, Andrew S., Levin, Nathan W., Levy, Jeremy, Lewington, Andrew, Li, Jennifer, Li, Li, Limonte, Christine P., Linas, Stuart L., Lok, Charmaine E., Macdougall, Iain C., Macedo, Etienne, MacGinley, Robert, Madero, Magdalena M., Magee, Colm, Malvar, Ana, Marshall, Mark, Marx, Nikolaus, Mathews, Ranjiv, Mattoo, Tej K., McCulloch, Mignon Irene, McDonald, Stephen Peter, Mellon, John, Miceli, Marisa H., Mirkov, Sanja, Morath, Christian, Fonseca, Nuno Moreira, Mulley, William R., Murtagh, Fliss, Mühlfeld, Anja Susanne, Nangaku, Masaomi, Nast, Cynthia C., Navarro, David, Neild, Guy H., Nicholson, Michael, Noris, Marina, O’Neill, W. Charles, Paine, Cary, Palmer, Biff F., Pannu, Neesh, Perazella, Mark A., Perico, Norberto, Pham, Phuong-Anh T., Pham, Phuong-Chi T., Pham, Phuong-Thu, Pham, Son, Phelps, Richard G., Pickering, Matthew, Polkinghorne, Kevan, Radhakrishnan, Jai, Rayner, Brian, Rayner, Hugh C., Reich, Heather N., Remuzzi, Giuseppe, DeMauro Renaghan, Amanda, Rheault, Michelle, Richards, A. Mark, Riella, Leonardo, Rodriguez-Iturbe, Bernardo, Ronco, Pierre, Rosenberg, Avi Z., Rosner, Mitchell, Ross, Michael, Rossert, Jerome, Rovin, Brad H., Ruggenenti, Piero L., Salant, David J., Samuels, Martin A., Sanders, Paul W., Sands, Jeff M., Santoriello, Dominick, Sarafidis, Pantelis, Schaenman, Joanna M., Schneider, Ronen, Segal, Mark S., Seifter, Julian Lawrence, Seneschall, Charlotte, Sethi, Sanjeev, Sharma, Kumar, Sharpe, Claire, Speer, Claudius, Sreelatha, M., Sridhar, Vikas S., Srisawat, Nattachai, Stenvinkel, Peter, Stites, Erik, Szerlip, Harold M., Tanaka, Tetsuhiro, Tang, Sydney C.W., Thomas, Chandra, Thurman, Joshua, Tonelli, Marcello, Tong, Li-Li, Topham, Peter S., Tordoir, Jan H.M., Torres, Vicente E., Touchard, Guy, Turner, Neil, Unwin, Robert John, Velez, Juan Carlos Q., Vervloet, Marc, Visweswaran, R. Kasi, Wanner, Christoph, Warner, Ross, Wasse, Haimanot, Weiner, I. David, Wheeler, David C., Wiles, Kate, Wilkie, Martin, Williams, Bryan, Wingo, Charles S., Wiseman, Alexander C., Womer, Karl L., Wong, Germaine, Wyld, Melanie, Wymer, David T.G., Wymer, David C., Yu, Xueqing, Zanella, Monica, Zeier, Martin, and Zhang, Hong

Published
2024
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41. List of Contributors

Author

Afshinnia, Farsad, primary, Agarwal, Anupam, additional, Appel, Gerald B., additional, Bagby, Susan P., additional, Bailey, James L., additional, Bakris, George L., additional, Barrett, Brendan J., additional, Bauer, Carolyn A., additional, Berl, Tomas, additional, Berns, Jeffrey S., additional, Bomback, Andrew, additional, Bose, Anirban, additional, Brosius, Frank C., additional, Brown, Lee K., additional, Bushinsky, David A., additional, Busse, Laurence W., additional, Campbell, Ruth C., additional, Cathro, Helen, additional, Chawla, Lakhmir S., additional, Chen, Sheldon, additional, Chertow, Glenn M., additional, Chew, Emily, additional, Chonchol, Michel, additional, Clive, David M., additional, Cohen, Debbie L., additional, Cohen, Lewis M., additional, Cohen, Scott D., additional, Collins, Ashte’ K., additional, Combs, Sara, additional, Correa-Rotter, Ricardo, additional, Cukor, Daniel, additional, Dalal, Monica, additional, Dancik, Tavis, additional, Davenport, Andrew, additional, Davison, Sara, additional, Zeeuw, Dick de, additional, Delanaye, Pierre, additional, Dharia, Sushma M., additional, Dobre, Mirela A., additional, Drawz, Paul, additional, Dreisbach, Albert W., additional, Emmett, Michael, additional, Fanton, John H., additional, Felsenfeld, Arnold J., additional, Fernandez, Hilda, additional, Flessner, Michael F., additional, Freedman, Barry I., additional, Fruchter, Yvette, additional, Furth, Susan L., additional, García-García, Guillermo, additional, Germain, Michael J., additional, Germino, Gregory G., additional, Goligorsky, Michael S., additional, Greenberg, Arthur, additional, Guay-Woodford, Lisa M., additional, Hawkins, Katrina, additional, Herzog, Charles A., additional, Holley, Jean L., additional, Hostetter, Thomas H., additional, House, Andrew A., additional, Hruska, Keith A., additional, Huan, Yonghong, additional, Ibrahim, Hassan N., additional, Imran, Nashat, additional, Iñiguez, Jonathan Chávez, additional, Isom, Robert T., additional, Jablonski, Kristen L., additional, Jhaveri, Kenar D., additional, Johansen, Kirsten, additional, Johnson, Richard J., additional, Junghare, Milind Y., additional, Kang, Duk-Hee, additional, Karadsheh, Feras F., additional, Kari, Jameela, additional, Kasiske, Bertram L., additional, Khoury, Charbel C., additional, Kimmel, Paul L., additional, Kopp, Jeffrey B., additional, Kummer, Andrew, additional, Heerspink, Hiddo J.Lambers, additional, Lerman, Lilach O., additional, Levin, Adeera, additional, Levine, Barton S., additional, Lew, Susie Q., additional, Mandayam, Sreedhar, additional, Mattoo, Tej K., additional, Maynard, Sharon E., additional, Meyer, Timothy W., additional, Mitch, William E., additional, Moss, Alvin H., additional, Moxey-Mims, Marva, additional, Muntner, Paul, additional, Murray, Anne M., additional, Nath, Karl A., additional, Neugarten, Joel, additional, No, Gloria, additional, Pahl, Madeleine V., additional, Paller, Mark S., additional, Palmer, Biff F., additional, Parfrey, Patrick S., additional, Patel, Samir S., additional, Pecoits-Filho, Roberto, additional, Peitzman, Steven J., additional, Peixoto, Aldo J., additional, Pham, Phuong-Chi T., additional, Pham, Phuong-Thu T., additional, Rabelink, Ton J., additional, Radhakrishnan, Jai, additional, Raed, Anas, additional, Raj, Dominic S., additional, Ramirez-Sandoval, Juan Carlos, additional, Reckelhoff, Jane F., additional, Ronco, Claudio, additional, Rosenberg, Mark E., additional, Rosner, Mitchell H., additional, Rovin, Brad, additional, Roy-Chaudhury, Prabir, additional, Ruebner, Rebecca, additional, Rule, Andrew D., additional, Sands, Jeff M., additional, Scheinman, Steven J., additional, Schlanger, Lynn E., additional, Seifert, Michael E., additional, Seliger, Stephen, additional, Singh, Ajay K., additional, Stendahl, John C., additional, Surendran, Kameswaran, additional, Textor, Stephen C., additional, Thadhani, Ravi I., additional, Townsend, Raymond R., additional, Unruh, Mark L., additional, Vassalotti, Joseph A., additional, Vaziri, Nosratola D., additional, Velasquez, Manuel T., additional, Ver Halen, Nisha, additional, Wang, Connie J., additional, Wanner, Christoph, additional, Weber, Marc, additional, Weir, Matthew R., additional, Wing, Maria R., additional, Winn, Michelle P., additional, Wymer, David C., additional, Yee, Jerry, additional, and Ziyadeh, Fuad N., additional

Published
2015
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43. Effects of Angiotensin II on Erythropoietin Production in the Kidney and Liver

Author

Yasuoka, Yukiko, primary, Izumi, Yuichiro, additional, Fukuyama, Takashi, additional, Inoue, Hideki, additional, Oshima, Tomomi, additional, Yamazaki, Taiga, additional, Uematsu, Takayuki, additional, Kobayashi, Noritada, additional, Shimada, Yoshitaka, additional, Nagaba, Yasushi, additional, Mukoyama, Masashi, additional, Sato, Yuichi, additional, Sands, Jeff M, additional, Kawahara, Katsumasa, additional, and Nonoguchi, Hiroshi, additional

Published
2021
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46. Supplemental Material, sj-pdf-6-brn-10.1177_10998004211016070 - Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers

Author

Houser, Madelyn C., Mac, Valerie, Smith, Daniel J., Chicas, Roxana C., Xiuhtecutli, Nezahualcoyotl, Flocks, Joan D., Elon, Lisa, Tansey, Malú Gámez, Sands, Jeff M., McCauley, Linda, and Hertzberg, Vicki S.

Subjects
111099 Nursing not elsewhere classified, FOS: Health sciences
Abstract

Supplemental Material, sj-pdf-6-brn-10.1177_10998004211016070 for Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers by Madelyn C. Houser, Valerie Mac, Daniel J. Smith, Roxana C. Chicas, Nezahualcoyotl Xiuhtecutli, Joan D. Flocks, Lisa Elon, Malú Gámez Tansey, Jeff M. Sands, Linda McCauley and Vicki S. Hertzberg in Biological Research For Nursing

Published
2021
Full Text
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47. Supplemental Material, sj-pdf-1-brn-10.1177_10998004211016070 - Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers

Author

Houser, Madelyn C., Mac, Valerie, Smith, Daniel J., Chicas, Roxana C., Xiuhtecutli, Nezahualcoyotl, Flocks, Joan D., Elon, Lisa, Tansey, Malú Gámez, Sands, Jeff M., McCauley, Linda, and Hertzberg, Vicki S.

Subjects
111099 Nursing not elsewhere classified, FOS: Health sciences
Abstract

Supplemental Material, sj-pdf-1-brn-10.1177_10998004211016070 for Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers by Madelyn C. Houser, Valerie Mac, Daniel J. Smith, Roxana C. Chicas, Nezahualcoyotl Xiuhtecutli, Joan D. Flocks, Lisa Elon, Malú Gámez Tansey, Jeff M. Sands, Linda McCauley and Vicki S. Hertzberg in Biological Research For Nursing

Published
2021
Full Text
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48. Supplemental Material, sj-pdf-9-brn-10.1177_10998004211016070 - Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers

Author

Houser, Madelyn C., Mac, Valerie, Smith, Daniel J., Chicas, Roxana C., Xiuhtecutli, Nezahualcoyotl, Flocks, Joan D., Elon, Lisa, Tansey, Malú Gámez, Sands, Jeff M., McCauley, Linda, and Hertzberg, Vicki S.

Subjects
111099 Nursing not elsewhere classified, FOS: Health sciences
Abstract

Supplemental Material, sj-pdf-9-brn-10.1177_10998004211016070 for Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers by Madelyn C. Houser, Valerie Mac, Daniel J. Smith, Roxana C. Chicas, Nezahualcoyotl Xiuhtecutli, Joan D. Flocks, Lisa Elon, Malú Gámez Tansey, Jeff M. Sands, Linda McCauley and Vicki S. Hertzberg in Biological Research For Nursing

Published
2021
Full Text
View/download PDF

49. Supplemental Material, sj-pdf-4-brn-10.1177_10998004211016070 - Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers

Author

Houser, Madelyn C., Mac, Valerie, Smith, Daniel J., Chicas, Roxana C., Xiuhtecutli, Nezahualcoyotl, Flocks, Joan D., Elon, Lisa, Tansey, Malú Gámez, Sands, Jeff M., McCauley, Linda, and Hertzberg, Vicki S.

Subjects
111099 Nursing not elsewhere classified, FOS: Health sciences
Abstract

Supplemental Material, sj-pdf-4-brn-10.1177_10998004211016070 for Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers by Madelyn C. Houser, Valerie Mac, Daniel J. Smith, Roxana C. Chicas, Nezahualcoyotl Xiuhtecutli, Joan D. Flocks, Lisa Elon, Malú Gámez Tansey, Jeff M. Sands, Linda McCauley and Vicki S. Hertzberg in Biological Research For Nursing

Published
2021
Full Text
View/download PDF

50. Supplemental Material, sj-pdf-8-brn-10.1177_10998004211016070 - Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers

Author

Houser, Madelyn C., Mac, Valerie, Smith, Daniel J., Chicas, Roxana C., Xiuhtecutli, Nezahualcoyotl, Flocks, Joan D., Elon, Lisa, Tansey, Malú Gámez, Sands, Jeff M., McCauley, Linda, and Hertzberg, Vicki S.

Subjects
111099 Nursing not elsewhere classified, FOS: Health sciences
Abstract

Supplemental Material, sj-pdf-8-brn-10.1177_10998004211016070 for Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers by Madelyn C. Houser, Valerie Mac, Daniel J. Smith, Roxana C. Chicas, Nezahualcoyotl Xiuhtecutli, Joan D. Flocks, Lisa Elon, Malú Gámez Tansey, Jeff M. Sands, Linda McCauley and Vicki S. Hertzberg in Biological Research For Nursing

Published
2021
Full Text
View/download PDF

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