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To evaluate Red blood cell distribution width (RDW) as a sepsis prognostic biomarker.203 septic patients admitted to the ICU. Analysis of RDW dynamics, hospital mortality discrimination ability and the added value when incorporated to the SOFA, LODS, SAPS-II and APACHE-II scores using the AUC-ROC.Non-survivors presented higher RDW values during the first week after ICU admission (p = 0.048). Only SOFA and RDW were independently associated with mortality when adjusted by Charlson, immunosuppression, nosocomial infection, NEWS2, SAPS-II, septic shock and haemoglobin (p0.05). After adjustment, AUC-ROC was 0.827, 0.822, 0.824, 0.834 and 0.812 for each model including admission, 24, 48 and 72-h and 7-days RDW, respectively. When added to the scores, 24-h RDW and admission RDW improved their discrimination ability (SOFA AUC-ROC = 0.772 vs 0.812 SOFA + admission RDW, p = 0.041; LODS AUC-ROC = 0.687 vs 0.710, p = 0.002; SAPS-II AUC-ROC = 0.734 vs 0.785, p = 0.021; APACHE-II AUC-ROC = 0.672 vs 0.755, p = 0.003). Admission RDW with SOFA presented the better discrimination ability for mortality.RDW is an independent prognostic marker of death in septic patients admitted in the ICU that improves SOFA, LODS, APACHE-II and SAPS-II discrimination ability. This parameter could be incorporated to the prognostic scores as a marker of systemic dysfunction and dysregulated inflammatory response.

Purpose: There are few studies that analyze the early and late outcomes of lung transplant (LTx) recipients who required admission in an ICU. We aim to evaluate the characteristics and outcomes of LTX recipients who were admitted to the ICU. Methods: A retrospective observacional study was performed in which we included 66 patients who were admitted to the ICU from July 2011 to June 2018. We analyze sex, pretransplant diagnoses, date and type of transplant, admission diagnoses, graft dysfunction before and after ICU admission, and outcomes. Results: There were 83 admissions in 66 patients: 7 were admitted twice and 1 patient three times. The characteristics of patients who died during the ICU stay vs the ones who were discharged alive can be found in Table 1. There were no significant differences. The most common admission diagnosis was infectious disease (59.1%). Twenty seven of 66 patients (40.9%) died during their ICU admission. The median survival for a lung transplant recipient after discharged from the ICU was 5 years (the survival curve can be seen in Figure 1). Fourteen patients developed graft dysfunction after ICU admission, and fifteen worsened their previous grade. Conclusion: Despite the high mortality associated with admission to the ICU the median survival after 5 years is more than 50 %. The most common ICU admission diagnosis was infectious disease. After ICU admission, almost half of the patients developed or worsened their grade of graft dysfunction.