14 results on '"Samuel Barreto"'
Search Results
2. Interbacterial Transfer of Carbapenem Resistance and Large Antibiotic Resistance Islands by Natural Transformation in Pathogenic Acinetobacter
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Anne-Sophie Godeux, Elin Svedholm, Samuel Barreto, Anaïs Potron, Samuel Venner, Xavier Charpentier, and Maria-Halima Laaberki
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AbaR ,Acinetobacter baumannii ,OXA23 ,type VI secretion system ,antibiotic resistance ,carbapenem resistance ,Microbiology ,QR1-502 - Abstract
ABSTRACT Acinetobacter baumannii infection poses a major health threat, with recurrent treatment failure due to antibiotic resistance, notably to carbapenems. While genomic analyses of clinical strains indicate that homologous recombination plays a major role in the acquisition of antibiotic resistance genes, the underlying mechanisms of horizontal gene transfer often remain speculative. Our understanding of the acquisition of antibiotic resistance is hampered by the lack of experimental systems able to reproduce genomic observations. We here report the detection of recombination events occurring spontaneously in mixed bacterial populations and which can result in the acquisition of resistance to carbapenems. We show that natural transformation is the main driver of intrastrain but also interstrain recombination events between A. baumannii clinical isolates and pathogenic species of Acinetobacter. We observed that interbacterial natural transformation in mixed populations is more efficient at promoting the acquisition of large resistance islands (AbaR4 and AbaR1) than when the same bacteria are supplied with large amounts of purified genomic DNA. Importantly, analysis of the genomes of the recombinant progeny revealed large recombination tracts (from 13 to 123 kb) similar to those observed in the genomes of clinical isolates. Moreover, we highlight that transforming DNA availability is a key determinant of the rate of recombinants and results from both spontaneous release and interbacterial predatory behavior. In the light of our results, natural transformation should be considered a leading mechanism of genome recombination and horizontal gene transfer of antibiotic resistance genes in Acinetobacter baumannii. IMPORTANCE Acinetobacter baumannii is a multidrug-resistant pathogen responsible for difficult-to-treat hospital-acquired infections. Understanding the mechanisms leading to the emergence of the multidrug resistance in this pathogen today is crucial. Horizontal gene transfer is assumed to largely contribute to this multidrug resistance. However, in A. baumannii, the mechanisms leading to genome recombination and the horizontal transfer of resistance genes are poorly understood. We describe experimental evidence that natural transformation, a horizontal gene transfer mechanism recently highlighted in A. baumannii, allows the highly efficient interbacterial transfer of genetic elements carrying resistance to last-line antibiotic carbapenems. Importantly, we demonstrated that natural transformation, occurring in mixed populations of Acinetobacter, enables the transfer of large resistance island-mobilizing multiple-resistance genes.
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- 2022
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3. CORPO, CURRÍCULO E RESISTÊNCIA: REFLEXÕES SOBRE AS CLASSES DE ACELERAÇÃO DA APRENDIZEGEM NA REDE MUNICIPAL DE NITERÓI
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Santos, Samuel Barreto dos, primary
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- 2019
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4. Collaborative Watershed Modeling as Stakeholder Engagement Tool for Science-Based Water Policy Assessment in São Paulo, Brazil
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Se Jong Cho, Claudio Klemz, Samuel Barreto, Justus Raepple, Henrique Bracale, Eileen Andrea Acosta, Carlos Andres Rogéliz-Prada, and Bruna S. Ciasca
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Geography, Planning and Development ,stakeholder engagement ,policy decision analysis ,collaborative modeling ,Aquatic Science ,hydrologic simulation model ,Biochemistry ,Water Science and Technology - Abstract
This study describes a collaborative modeling process deployed at the Cantareira Water Supply System (CWSS) in São Paulo City Metropolitan Area, Brazil. The CWSS faces challenges for meeting the increasing water demand, while land-use and climate change and their combined effect on its water cycle and balance have created a complex water resources management problem. Through a stakeholder engagement process—involving scientists and policymakers, the water utility company, and state administration—environmental simulation models were developed to elicit and represent multiple environmental, economic, and policy perspectives, developing a mutual language to communicate and establish common goals of water resources management. Study outputs include estimation of biophysical and economic benefits associated with prioritized native vegetation restoration activities in the source watersheds. These outputs are deployed in support of landscape planning and the decision process integrating multiple stakeholder perspectives in São Paulo state administration, the water utility company, and municipalities.
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- 2023
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5. Biophysical Benefits Simulation Modeling Framework for Investments in Nature-Based Solutions in São Paulo, Brazil Water Supply System
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Eileen Andrea Acosta, Se Jong Cho, Claudio Klemz, Justus Reapple, Samuel Barreto, Bruna Stein Ciasca, Jorge León, Carlos Andres Rogéliz-Prada, and Henrique Bracale
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landscape scenarios ,Geography, Planning and Development ,HEC-HMS ,SWAT ,Aquatic Science ,water security ,Biochemistry ,nature-based solutions ,hydrologic model ,Water Science and Technology - Abstract
In order to understand the hydrological impacts of the nature-based solutions in the Cantareira Water Supply System, this study evaluates six different land cover and land use change scenarios. The first and second consider the restoration of native vegetation in riparian areas, the third prioritizes restoration sites using biophysical characteristics (optimized restoration scenario derived from Resource Investment Optimization System—RIOS), the fourth considers best management practices and the fifth and sixth are hypothetical extreme scenarios converting all pasture to forest and vice versa. Two hydrological models were developed to represent the distributions of water and yields in the study watershed: HEC-HMS and SWAT. Simulation results indicate that when nature-based solutions are implemented, surface runoff is reduced and ambient storage increases during the rainy season (December–March); while the overall flow increases during the dry season (June–September). The combination of specific hydrologic components of RIOS-customized intervention scenario simulation outputs—namely surface flows and groundwater contribution to stream flows—indicate on average 33% increase in the overall water yield, or 206 hm3/year, across the study watershed when comparing against the baseline conditions. In the same modeling scenario, the water storage in the sub-watersheds adjacent to the reservoirs showed an increase of 58% (or 341 hm3/year). The results indicate that adopting NbS in the source watershed can mitigate the impacts of extreme drought conditions and contribute toward building long-term water security.
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- 2023
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6. Economic Cost of Drought and Potential Benefits of Investing in Nature-Based Solutions: A Case Study in São Paulo, Brazil
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Bruna Stein Ciasca, Claudio Klemz, Justus Raepple, Timm Kroeger, Eileen Andrea P. Acosta, Se Jong Cho, Samuel Barreto, Henrique Bracale, and Fernando Cesário
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drought resilience ,economic cost of drought ,Geography, Planning and Development ,cost–benefit analysis ,Aquatic Science ,water security ,Biochemistry ,nature-based solutions ,economic benefits of NbS ,Water Science and Technology - Abstract
Despite its rich water resources, Brazil is increasingly facing extreme hydrologic events such as droughts and floods. The Sao Paulo Cantareira water supply system (CWSS) offers an opportunity to examine the potential economic benefits of nature-based solutions (NbS) to improve water security and reduce the economic cost of drought. This study explores the potential benefits under a counterfactual NbS land-use scenario compared to actual land use and assesses the economic viability of NbS investments in the CWSS. Specifically, we estimate the economic cost of the 2014–2015 drought in Sao Paulo state for the industrial and water sectors served by the CWSS. We estimate the potential avoided costs under the NbS scenario and conduct a cost–benefit analysis of the NbS scenario investments, including both water supply and carbon sequestration benefits. We estimate that the economic losses of this single drought event totaled BRL 1.6 billion. If NbS had been implemented, this cost could have been reduced by 28%. A cost–benefit analysis that includes only the water supply or both the water supply and carbon sequestration benefits indicates that the NbS scenario has a positive net present value of BRL 144 million and BRL 632 million, respectively. Thus, our results highlight the economic viability of the hypothetical NbS investment in mitigating extreme climatic events.
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- 2023
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7. Author Correction: Complex ecological interactions of Staphylococcus aureus in tampons during menstruation
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Samuel Barreto, Michèle Bes, Gery Lamblin, Jean-Philippe Rasigade, Anne Tristan, Daniel Muller, Tristan Ferry, Y. Gillet, François Golfier, Claire Prigent-Combaret, Jean Thioulouse, Danis Abrouk, Gerard Lina, Isaline Jacquemond, Audrey Dubost, Anaëlle Muggeo, Pierre Adrien Bolze, and Claude Alexandre Gustave
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Adult ,Staphylococcus aureus ,lcsh:Medicine ,medicine.disease_cause ,Microbiology ,Young Adult ,RNA, Ribosomal, 16S ,Medicine ,DNA Barcoding, Taxonomic ,Humans ,lcsh:Science ,Author Correction ,Menstrual Hygiene Products ,Multidisciplinary ,Bacteria ,business.industry ,Microbiota ,lcsh:R ,Staphylococcal Infections ,During menstruation ,Shock, Septic ,Menstruation ,Vagina ,lcsh:Q ,Female ,business ,Tampon - Abstract
Menstrual toxic shock syndrome (mTSS) is a severe disease that occurs in healthy women vaginally colonized by Staphylococcus aureus producing toxic shock toxin 1 and who use tampons. The aim of the present study was to determine the impact of the composition of vaginal microbial communities on tampon colonisation by S. aureus during menses. We analysed the microbiota in menstrual fluids extracted from tampons from 108 healthy women and 7 mTSS cases. Using culture, S. aureus was detected in menstrual fluids of 40% of healthy volunteers and 100% of mTSS patients. Between class analysis of culturomic and 16S rRNA gene metabarcoding data indicated that the composition of the tampons' microbiota differs according to the presence or absence of S. aureus and identify discriminating genera. However, the bacterial communities of tampon fluid positive for S. aureus did not cluster together. No difference in tampon microbiome richness, diversity, and ecological distance was observed between tampon vaginal fluids with or without S. aureus, and between healthy donors carrying S. aureus and mTSS patients. Our results show that the vagina is a major niche of. S. aureus in tampon users and the composition of the tampon microbiota control its virulence though more complex interactions than simple inhibition by lactic acid-producing bacterial species.
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- 2020
8. slide soutenance de thèse
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Samuel, Barreto
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La soutenance de ma thèse.Placée ici en backup.Je ne détiens pas les droits pour certaines images de la présentation. Shame on me.
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- 2020
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9. Complex ecological interactions of Staphylococcus aureus in tampons during menstruation
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Michèle Bes, Gery Lamblin, Jean Thioulouse, Audrey Dubost, François Golfier, Isaline Jacquemond, Daniel Muller, Anne Tristan, Samuel Barreto, Yves Gillet, Danis Abrouk, Claude Alexandre Gustave, Tristan Ferry, Jean-Philippe Rasigade, Anaëlle Muggeo, Gerard Lina, Pierre Adrien Bolze, Claire Prigent-Combaret, Pathogénie des Staphylocoques – Staphylococcal Pathogenesis, Centre International de Recherche en Infectiologie - UMR (CIRI), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Hôpital Femme Mère Enfant [CHU - HCL] (HFME), Hospices Civils de Lyon (HCL), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Centre National de Reference des Staphylocoques, Université de Lyon, Hôpital de la Croix-Rousse [CHU - HCL], Laboratoire d'Ecologie Microbienne - UMR 5557 (LEM), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Ecole Nationale Vétérinaire de Lyon (ENVL)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Ecologie quantitative et évolutive des communautés, Département écologie évolutive [LBBE], Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Ecole Nationale Vétérinaire de Lyon (ENVL)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Pathogénie des Staphylocoques – Staphylococcal Pathogenesis (StaPath), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service de Chirurgie Gynécologique Oncologique et Obstétrique [CHU Lyon Sud], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Service de Maladies Infectieuses et Tropicales [Hôpital de la Croix-Rousse - HCL], LABEX ECOFECT of Universite de Lyon within the programme 'Investissements d'Avenir' ANR-11-LABX-0048, ANR-11-IDEX-0007, Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Ecole Nationale Vétérinaire de Lyon (ENVL), Institut National de la Santé et de la Recherche Médicale (INSERM)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Davoine, Laure-Hélène, Service de Chirurgie Gynécologique et Oncologique – Obstétrique [CHU Lyon Sud], Service des Maladies Infectieuses et Tropicales [Hôpital de la Croix-Rousse, CHU-HCL], Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Vétérinaire de Lyon (ENVL)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Institut National de la Recherche Agronomique (INRA)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)
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staphylococcus aureus ,0301 basic medicine ,[SDV.IMM] Life Sciences [q-bio]/Immunology ,[SDV]Life Sciences [q-bio] ,femme ,030106 microbiology ,microbiome ,Virulence ,Severe disease ,lcsh:Medicine ,Biology ,[SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics ,medicine.disease_cause ,Article ,Microbiology ,03 medical and health sciences ,microbiote ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,medicine ,Microbiome ,lcsh:Science ,ComputingMilieux_MISCELLANEOUS ,cycle menstruel ,[SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology ,communauté microbienne ,Multidisciplinary ,lcsh:R ,Toxic shock syndrome ,santé humaine ,medicine.disease ,During menstruation ,equipment and supplies ,[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology ,3. Good health ,medicine.anatomical_structure ,Staphylococcus aureus ,[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology ,Vagina ,[SDV.IMM]Life Sciences [q-bio]/Immunology ,lcsh:Q ,[SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology ,Tampon - Abstract
Menstrual toxic shock syndrome (mTSS) is a severe disease that occurs in healthy women vaginally colonized by Staphylococcus aureus producing toxic shock toxin 1 and who use tampons. The aim of the present study was to determine the impact of the composition of vaginal microbial communities on tampon colonisation by S. aureus during menses. We analysed the microbiota in menstrual fluids extracted from tampons from 108 healthy women and 7 mTSS cases. Using culture, S. aureus was detected in menstrual fluids of 40% of healthy volunteers and 100% of mTSS patients. Between class analysis of culturomic and 16S rRNA gene metabarcoding data indicated that the composition of the tampons’ microbiota differs according to the presence or absence of S. aureus and identify discriminating genera. However, the bacterial communities of tampon fluid positive for S. aureus did not cluster together. No difference in tampon microbiome richness, diversity, and ecological distance was observed between tampon vaginal fluids with or without S. aureus, and between healthy donors carrying S. aureus and mTSS patients. Our results show that the vagina is a major niche of. S. aureus in tampon users and the composition of the tampon microbiota control its virulence though more complex interactions than simple inhibition by lactic acid-producing bacterial species.
- Published
- 2018
- Full Text
- View/download PDF
10. CORPO, CURRÍCULO E RESISTÊNCIA: REFLEXÕES SOBRE AS CLASSES DE ACELERAÇÃO DA APRENDIZEGEM NA REDE MUNICIPAL DE NITERÓI
- Author
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Samuel Barreto dos Santos
- Published
- 2019
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- View/download PDF
11. The Law 13.278/16 and the production process of curriculum for the dance in basic education
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Santos, Samuel Barreto dos, Pereira, Talita Vidal, Souza, Flávia Faissal de, and Oliveira, Thiago Ranniery de
- Subjects
Knowledge ,Dança na educação ,Dance Teaching ,Pós-estruturalismo ,Post-structuralism ,Conhecimento ,Currículo ,Curriculum ,Componente Curricular ,CIENCIAS HUMANAS::EDUCACAO [CNPQ] ,Disciplinarização - Abstract
Submitted by Boris Flegr (boris@uerj.br) on 2021-01-05T21:35:53Z No. of bitstreams: 1 Dissertacao Samuel Barreto dos Santos.pdf: 472007 bytes, checksum: 702a57b1ec566884fc8e54667ec8c589 (MD5) Made available in DSpace on 2021-01-05T21:35:53Z (GMT). No. of bitstreams: 1 Dissertacao Samuel Barreto dos Santos.pdf: 472007 bytes, checksum: 702a57b1ec566884fc8e54667ec8c589 (MD5) Previous issue date: 2018-12-06 This study aims to analyze the meanings of curriculum articulated in speeches in defense of dance as a curricular component of Basic Education. This is a documentary analysis of the annals of the National Scientific Meeting of researchers in Dance (ANDA) and the meeting of Research Groups in Dance (ENGRUPEdança) to verificate under what conceptions of curriculum if raise such defenses. The research brings, in its first part, a ransom of curricular theorizations, without dwelling in theorizations of history. Uses as examining the concept of curriculum as enunciation, to discuss how the body produces curriculum through the performativity of movement. Raises the questioning about the dangers of disciplinarization of dance as a artistic language that could lose many of their properties and compromising your potential of decolonization of bodies. In the third and last chapter, is made a description of the arguments raised in the annals of ENGRUPEdança and ANDA, in defense for the implementation of dance as a discipline in the curriculum of basic education. This chapter discusses too the knowledge constructed in raising these discourses, reflecting about these discussions from other theoretical frameworks that enable other reflections. Finally, it analyzes the defense of dance as a knowledge inserted in the arguments of disciplinarização dance, alerting to the possibilities of adjustment and standardization of the content of dance, if recognized as a knowledge disciplinary and schooling. Esse estudo tem como objetivo analisar os sentidos de currículo articulados nos discursos em defesa da dança como componente curricular da Educação Básica. Para tal, realiza-se uma análise documental dos anais do Encontro Científico Nacional de Pesquisadores em Dança (ANDA) e do Encontro de Grupos de Pesquisa em Dança (ENGRUPEdança) para verificar sob quais concepções de currículo se erguem tais defesas. A pesquisa traz, na sua primeira parte, um breve resgate das teorizações curriculares, com ênfase nos aportes pós-estruturalistas. Analisa-se o conceito de currículo como enunciação, para discutir como o corpo produz currículo através da performatividade do movimento. Levanta-se a problematização sobre os perigos de se disciplinarizar a dança, podendo essa linguagem artística perder muitas de suas propriedades e comprometer o seu potencial de descolonização dos corpos. No terceiro e ultimo capítulo, é realizada, de início, uma descrição dos argumentos levantados nos anais do ENGRUPEdança e do ANDA, na defesa pela implementação da dança como disciplina do currículo da educação básica. Ainda nesse capítulo, problematiza-se os conhecimentos construídos no erguer desses discursos, refletindo nessas discussões a partir de outros aportes teóricos que possibilitam outras reflexões. Por fim, problematiza-se a defesa da dança como conhecimento inserida nas argumentações para a disciplinarização da dança, alertando-se para as possibilidades de regulação e normatização dos conteúdos da dança, se reconhecida como um conhecimento disciplinarizado e escolarizado.
- Published
- 2018
12. CLASSES DE ACELERAÇÃO DA APRENDIZAGEM: CORPOS RESISTENTES A UMA EDUCAÇÃO COLONIZADORA. ACCELERATED LEARNING CLASSES: BODIES THAT RESIST TO A COLONIZING EDUCATION
- Author
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Samuel Barreto dos Santos
- Subjects
General Medicine - Abstract
O presente trabalho tem como objetivo desenvolver as propostascaracterísticas da concepção das classes de aceleração da aprendizagem noMunicípio de Niterói, com breves relatos sobre sua idealização em nívelnacional, em 1996, e sua expansão para alguns estados. Após um debate sobrecomo essa proposta tem acontecido na rede municipal de Niterói, desenvolvoalguns relatos de experiência da minha prática como docente desse grupo,trazendo uma breve reflexão sobre como o grupo característico demonstrafortes resistências aos processos de escolarização reguladores que contribuemdemasiadamente com os processos de colonização do corpo
- Published
- 2017
- Full Text
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13. Participatory river basin management in the São João River, Brazil: A basis for climate change adaptation?
- Author
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Samuel Barreto, Luiz Firmino Martins Pereira, and Jamie Pittock
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Global and Planetary Change ,Adaptive capacity ,geography.geographical_feature_category ,Geography, Planning and Development ,Stakeholder ,Drainage basin ,Climate change ,Citizen journalism ,Development ,Structural basin ,Geography ,Environmental protection ,Water quality ,Environmental degradation ,Environmental planning - Abstract
This paper describes an empirical case study of enhanced water management in the Sao Joao River basin on the southeast coast of Brazil between 1999 and 2008. The autonomous adaptation measures applied are assessed to derive lessons for more effective climate change adaptation. In response to severe eutrophication of their coastal lakes, effective, local multi-stakeholder institutions were established under the auspices of the Consorcio Intermunicipal Lagos Sao Joao from 1999 to improve basin management. Having significantly reduced the pollution problem, other environmental challenges are now being addressed. In managing environmental problems with multiple causes and effects, engaging multiple stakeholders and communicating the need to change environmental management, these local institutions have established the types of capacities needed for climate change adaptation. Factors contributing to the strengthening of this adaptive capacity include: engagement of local non-governmental organizations, compani...
- Published
- 2009
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14. Identification of multiple sclerosis brain lesions in magnetic resonance imaging using texture analysis
- Author
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Nelson Fabián Orozco Higuera, Samuel Barreto Melo, and César Augusto Aldana Ramírez
- Abstract
La esclerosis múltiple (EM) es una enfermedad neurodegenerativa que ataca al sistema nervioso central (SNC), produce lesiones desmielinizantes y causa secuelas funcionales en adultos jóvenes, especialmente mujeres. Su diagnóstico y seguimiento se realizan a través de la resonancia magnética. En la actualidad, el análisis de texturas se ha convertido en una herramienta útil para la detección de este tipo lesiones. Por tal razón, en este artículo se busca identificar lesiones de EM utilizando los métodos de matrices de co-ocurrencia de nivel de gris y transformada wavelet (TW), y como métodos de clasificación redes neuronales (ANN) y máquinas de soporte vectorial (SVM) en imágenes de resonancia magnética (RMI) en secuencia FLAIR de 5 pacientes con diagnóstico de la enfermedad. La combinación apropiada de medidas de matrices de co-ocurrencia y wavelets permitieron obtener precisiones superiores a 96% para las máquinas de soporte vectorial y 90% para las redes neuronales, lo que demuestra que el uso combinado de dichas medidas es superior en la detección de estas lesiones.
- Published
- 2014
- Full Text
- View/download PDF
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