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554 results on '"Samsom M"'

3. High frequency of early colorectal cancer in inflammatory bowel disease

Author

Lutgens, M.W.M.D., Vleggaar, F.P., Schipper, M.E.I., Stokkers, P.C.F., van der Woude, C.J., Hommes, D.W., de Jong, D.J., Dijkstra, G., van Bodegraven, A.A., Oldenburg, B., and Samsom, M.

Subjects
Colorectal cancer -- Diagnosis, Inflammatory bowel diseases -- Complications and side effects, Colonoscopy -- Analysis, Health
Published
2008

12. Effect of intragastric barostat bag on proximal and distal gastric accommodation in response to liquid meal

Author

Mundt, M.W., Hausken, T., and Samsom, M.

Subjects
Molecular biology -- Research, Ultrasonics -- Evaluation, Pylorus -- Physiological aspects, Stomach -- Research, Biological sciences
Abstract

The barostat is the gold standard for measurement of proximal gastric accommodation. Ultrasonography can be used to measure gastric volume. The aim was to investigate the effects of the barostat bag on gastric accommodation and transpyloric flow. Accommodation after a liquid meal (300 ml, 450 kcal) was measured twice at random in eight healthy volunteers. Proximal accommodation was measured once using barostat and once using ultrasound (US). Antrum accommodation was measured using US. Bag volume (BV), antral area (AA), proximal gastric area, and proximal gastric diameter (PGD) data were assessed before and 1, 5, 15, 30, 40, 50, and 60 min postprandially. Transpyloric flow was measured using Doppler 1-5 min postprandially. Fasted, AA size was not affected by the barostat bag (1 mmHg > minimal distension pressure; 2.7 [+ or -] 0.5 vs. 2.6 [+ or -] 0.3 [cm.sup.2]). Postprandially, AAs were larger with the bag present (ANOVA, P < 0.04). Maximum AA was reached with the bag in 5 min, without the bag in 1 min postprandially (15.1 [+ or -] 2.3 vs. 9.4 [+ or -] 1.5 [cm.sup.2]; P < 0.03). Furthermore, AAs were related to BVs (r = 0.57; P < 0.01). After bag deflation, AA decreased (11.9 [+ or -] 1.8 to 7.0 [+ or -] 0.9 [cm.sup.2]; P = 0.02) and was comparable with the 60-min AA size without the bag (7.1 [+ or -] 1.2 [cm.sup.2]; P = 0.76) present. Proximal gastric radius calculated from the BVs and PGDs was larger with the bag present (ANOVA, P < 0.001). No effect on early gastric emptying was observed. Postprandially, the barostat bag causes dilatation of the antrum due to meal displacement without influencing early gastric emptying. This antral dilatation is likely to induce exaggerated proximal gastric relaxation observed in studies using the barostat to evaluate fundic accommodation. transpyloric flow; ultrasonography; accommodation; antral area

Published
2002

13. Intraduodenal conjugated bile salts exert negative feedback control on gall bladder emptying in the fasting state without affecting cholecystokinin release or antroduodenal motility. (Biliary Tract)

Author

Ooteghem, N.A.M. van, Moschetta, A., Rehfeld, J.F., Samsom, M., Erpecum, K.J. van, and Berge-Henegouwen, G.P. van

Subjects
Gallbladder -- Physiological aspects, Gastrointestinal system -- Motility, Health, Physiological aspects
Abstract

Background: Intraduodenal bile salts exert negative feedback control on postprandial gall bladder emptying. Aims: We wished to examine whether a similar control mechanism occurs in the fasting state. Methods: Intraduodenal [...]

Published
2002

15. Prolonged manometric recordings of oesophagus and lower oesophageal sphincter in achalasia patients. (Motility and visceral sensation)

Author

Herwaarden, M.A. van, Samsom, M., and Smout, A.J.P.M.

Subjects
Esophagogastric junction -- Physiological aspects, Achalasia -- Diagnosis, Health, Diagnosis, Physiological aspects
Abstract

Abstract Background and aims---Conventional short term manometry is a valuable tool in the diagnosis of achalasia but the technique may fail to detect intermittent motor events. The aim of this [...]

Published
2001

19. Physiological changes in blood glucose do not affect gastric compliance and perception in normal subjects

Author

Verhagen, M.A.M.T., Rayner, C.K., Andrews, J.M., Hebbard, G.S., Doran, S.M., Samsom, M., and Horowitz, M.

Subjects
Blood sugar -- Physiological aspects, Gastrointestinal system -- Physiological aspects, Biological sciences
Abstract

Research was conducted to find out whether physiological changes in blood glucose influence proximal gastric compliance and/or the perception of gastric distension in the fasting state. Paired studies were performed in 10 fasting healthy volunteers. Results showed that in the fasting state, increases in the amount of blood glucose within the physiological range do not have an effect on proximal gastric compliance or the perception of gastric distension.

Published
1999

32. Effects of intraduodenal glucose infusion on gastric myoelectrical activity and antropyloroduodenal motility

Author

Verhagen, M.A.M.T., Samsom, M., and Smout, A.J.P.M.

Subjects
Electrogastrography -- Research, Duodenum -- Physiological aspects, Gastrointestinal system -- Motility, Glucose -- Physiological aspects, Biological sciences
Abstract

A study was conducted on the involvement of gastric myoelectrical activity in intestinogastric feedback mechanisms and its relation to changes in gastric and pyloric motor activity during intraduodenal glucose infusion. The findings indicate that inhibition of gastric myoelectrical activity is one of the mechanisms by which motor activity in the gastric antrum is inhibited.

Published
1998

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