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3. Frequency of Microalbuminuria in Essential Hypertension and type II Diabetes Mellitus in Tertiary Care Hospital

Author

Somia Tariq, Irfan Raheem, Ishtiaque Ahmed Mahar, and Samiya Rehman

Abstract

Introduction: Hypertension is the growing issues of public health problem of adult population in both developed as well as developing world, affecting single person in every four people. Objectives: The main objective of the study is to find the frequency of microalbuminuria in essential hypertension in tertiary care hospitals. Material and Methods: This Randomized Control Trial was conducted in DHQ hospital Sahiwal during 2020 to 2021. Blood sample of all the patients diagnosed with microalbuminuria in hypertension presented to the hospital were taken and sent to laboratory for performing fasting blood glucose and 1st morning Urine sample was taken and analyzed for albumin to creatinine ratio of these patients. Results: The age range of patients in this research was from 18-75 years. The mean age of patients was 40.35 ± 8.65 years. In group A the mean age of patients was 39.60 ± 10.12 years and in group B was 41.0 ± 8.05 years. Conclusion: This study concluded that efficacy of losartan is higher than lisinopril for reduction of microalbuminuria in patients with type-2 diabetes mellitus. Keywords: type II diabetes, microalbuminuria, losartan.

Published
2022
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4. List of contributors

Author

Asim Abbasi, Seyed Abdollah Hosseini, Sobia Afzal, Adeel Ahmad, Iftikhar Ahmad, Zahoor Ahmad, Muhammad Ali, Abdullah Alsaeedi, Tarek Alshaal, Megahed Amer, Muhammad Arslan Arshraf, Arkadiusz Artyszak, Muhammad Ashar Ayub, Celaleddin Barutçular, Zaffar Bashir, Aneesa Batool, Kaisar Ahmad Bhat, Cid Naudi Silva Campos, Zhong-Liang Chen, Muhammad Dawood, Renato de Mello Prado, Amanda Carolina Prado de Moraes, Jonas Pereira de Souza Júnior, Heba Elbasiony, Fathy Elbehery, Alaa El-Dein Omara, Mohamed M. Elgarawani, Nevien Elhawat, Hassan El-Ramady, Tamer Elsakhawy, Hugo Fernando Escobar-Sepúlveda, Hassan Etesami, Saad Farouk, Patrícia Messias Ferreira, Fernando Carlos Gómez-Merino, Libia Fernanda Gómez-Trejo, Roghieh Hajiboland, Robert Henry, Mohammad Anwar Hossain, Iqbal Hussain, Muhammad Ammir Iqbal, Muhammad Jafir, Mallikarjuna Jeer, Byoung Ryong Jeong, Danuta Kaczorek, C.M. Kalleshwaraswamy, Muhammad Kamran, M. Kannan, Norollah Kheyri, Paulo Teixeira Lacava, Yang-Rui Li, Zaffar Malik, Madeeha Mansoor, Madhiya Manzoor, Piyush Mathur, Tatiana Minkina, Seyed Majid Mousavi, Sahar Mumtaz, Momina Nazir, Fatemeh Noori, Sana Noreen, Aasma Parveen, Abida Parveen, Shagufta Perveen, N.B. Prakash, Daniel Puppe, Vishnu D. Rajput, Rizwan Rasheed, Samiya Rehman, Muhammad Riaz, Saima Riaz, Swarnendu Roy, Freeha Sabir, Muhammad Hamzah Saleem, Mahima Misti Sarkar, Jörg Schaller, Ehsan Shokri, Munna Singh, Xiu-Peng Song, Syeda Refat Sultana, Gelza Carliane Marques Teixeira, Sumaira Thind, Dan-Dan Tian, Libia Iris Trejo-Téllez, Muhammad Zia ur Rehman, Krishan K. Verma, Ejaz Ahmad Waraich, Danghui Xu, Sajad Majeed Zargar, and Saman Zulfiqar

Published
2022
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8. Author Correction: Drier Climatic Conditions Increase Withanolide Content of Withania coagulans Enhancing its Inhibitory Potential against Human Prostate Cancer Cells

Author

Ken Keefover-Ring, Samiya Rehman, Ihsan-ul Haq, Erum Dilshad, Mohammad Imran Khan, Bushra Mirza, and Nosheen Akhtar

Subjects
Withania coagulans, Inhibitory potential, food.ingredient, Traditional medicine, Bioengineering, General Medicine, Biology, Applied Microbiology and Biotechnology, Biochemistry, Human prostate, chemistry.chemical_compound, food, Withanolide, chemistry, Cancer cell, Molecular Biology, Biotechnology
Abstract

The original version of this article unfortunately contained a mistake in the image of Figure 1 and in Table 4. The corrected version of the figure and table is shown here.

Published
2019
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9. Drier Climatic Conditions Increase Withanolide Content of Withania coagulans Enhancing Its Inhibitory Potential Against Human Prostate Cancer Cells

Author

Ken Keefover-Ring, Ihsan-ul Haq, Erum Dilshad, Mohammad Imran Khan, Samiya Rehman, Nosheen Akhtar, and Bushra Mirza

Subjects
0106 biological sciences, Withania coagulans, Male, food.ingredient, Climate, Bioengineering, Apoptosis, Biology, Withania, 01 natural sciences, Applied Microbiology and Biotechnology, Biochemistry, chemistry.chemical_compound, Prostate cancer, food, Dry weight, Cell Movement, 010608 biotechnology, Cell Line, Tumor, medicine, Humans, Pakistan, Viability assay, Molecular Biology, Withanolides, Cell Proliferation, Plants, Medicinal, Traditional medicine, 010405 organic chemistry, Plant Extracts, Cancer, Prostatic Neoplasms, General Medicine, medicine.disease, Antineoplastic Agents, Phytogenic, 0104 chemical sciences, Plant Leaves, Withanolide, chemistry, Cancer cell, Drug Screening Assays, Antitumor, Biotechnology, Phytotherapy
Abstract

Prostate cancer is one of the major causes of cancer-related deaths in men and there is a growing interest in identifying natural compounds for its management. We analyzed bioactive withanolides in Withania coagulans from 11 different sites in Pakistan and evaluated the antiprostate cancer activities of leaf extracts from two sites with the greatest amounts. Total withanolide concentration differed by ~ 17-fold between sites, ranging from 1.01 ± 0.01 mg/g dry weight (mean ± SE) at Jand to 16.83 ± 0.02 mg/g at Mohmand Agency. Different tissues varied in their total withanolide content with roots having the least (0.42 ± 0.07 mg/g dry weight) and leaves the most (2.45 ± 0.45 mg/g). We found strong inverse correlations between site annual precipitation versus withanolide amounts in fruits (r = − 0.84, P = 0.001), leaves (r = − 0.88, P

Published
2018

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