1. Coronary Artery Bypass Grafting in Patients With High Risk of Bleeding
- Author
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Tatu Juvonen, Daniele Maselli, Eric Bibiza, Samira Fehr, Marco Zanobini, Ciro Bancone, Antonio Salsano, Giovanni Mariscalco, Magnus Dalén, B. Reiter, Matteo Saccocci, Fausto Biancari, Francesco Santini, Antonino S. Rubino, Timo H. Mäkikallio, Karl Bounader, Marisa De Feo, Till Demal, Vito G. Ruggieri, Francesco Nicolini, Giuseppe Faggian, Giuseppe Gatti, Andrea Perrotti, Francesco Onorati, Francesco Musumeci, Giuseppe Santarpino, Hermann Reichenspurner, Demal, T. J., Fehr, S., Mariscalco, G., Reiter, B., Bibiza, E., Reichenspurner, H., Gatti, G., Onorati, F., Faggian, G., Salsano, A., Santini, F., Perrotti, A., Santarpino, G., Zanobini, M., Saccocci, M., Musumeci, F., Rubino, A. S., De Feo, M., Bancone, C., Nicolini, F., Dalen, M., Maselli, D., Bounader, K., Makikallio, T., Juvonen, T., Ruggieri, V. G., and Biancari, F.
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Coronary Artery Bypass, Off-Pump ,Cardiopulmonary bypa ,law.invention ,Postoperative Complications ,law ,Atrial Fibrillation ,medicine ,Cardiopulmonary bypass ,Off-Pump ,Humans ,Coronary Artery Bypass ,CABG ,Bleeding complication ,Retrospective Studies ,Framingham Risk Score ,Cardiopulmonary Bypass ,business.industry ,Atrial fibrillation ,Perioperative ,medicine.disease ,Intensive care unit ,Confidence interval ,Surgery ,Cardiac surgery ,medicine.anatomical_structure ,Treatment Outcome ,Bleeding complications ,Cardiology and Cardiovascular Medicine ,business ,Artery ,Off-pump - Abstract
Background: Postoperative bleeding after cardiac surgery is associated with increased morbidity and mortality. We tested the hypothesis that patients with a preoperatively estimated high risk of severe perioperative bleeding may have impaired early outcome after on-pump versus off-pump coronary artery bypass grafting (CABG). Method: Data from 7,352 consecutive patients who underwent isolated CABG from January 2015 to May 2017 were included in the multicentre European Coronary Artery Bypass Grafting registry. The postoperative bleeding risk was estimated using the WILL-BLEED risk score. Of all included patients, 3,548 had an increased risk of severe perioperative bleeding (defined as a WILL-BLEED score ≥4) and were the subjects of this analysis. We compared the early outcomes between patients who underwent on-pump or off-pump CABG using a multivariate mixed model for risk-adjusted analysis. Results: Off-pump surgery was performed in 721 patients (20.3%). On-pump patients received more packed red blood cell units (on-pump: 1.41 [95% confidence interval {CI}, 0.99–1.86]; off-pump: 0.86 [95% CI, 0.64–1.08]; p
- Published
- 2022