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4. Postpartum-specific Vital Sign Reference Ranges

Author

Green, L.J., Pullon, R., Mackillop, L.H., Gerry, S., Birks, J., Salvi, D., Davidson, S., Loerup, L., Tarassenko, L., Mossop, J., Edwards, C., Gauntlett, R., Harding, K., Chappell, L.C., Knight, M., and Watkinson, P.J.

Published
2022
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5. Postpartum-specific Vital Sign Reference Ranges

Author

Green, L.J., Pullon, R., Mackillop, L.H., Gerry, S., Birks, J., Salvi, D., Davidson, S., Loerup, L., Tarassenko, L., Mossop, J., Edwards, C., Gauntlett, R., Harding, K., Chappell, L.C., Knight, M., and Watkinson, P.J.

Published
2021
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11. Artificial intelligence-assisted small bowel capsule endoscopy reading in patients with suspected small bowel bleeding

Author

Piccirelli, S., additional, Hassan, C., additional, Toth, E., additional, Gonzalez, B., additional, Keuchel, M., additional, McAlindon, M., additional, Finta, A., additional, Rosztoczy, A., additional, Dray, X., additional, Salvi, D., additional, Riccioni, M. E., additional, Benamouzig, R., additional, Chattree, A., additional, Saurin, J. C., additional, Humphries, A., additional, Despott, E., additional, Murino, A., additional, Johansson, G. Wurm, additional, Giordano, A., additional, Baltes, P., additional, Sidhu, R., additional, Szalai, M., additional, Helle, K., additional, Nemeth, A., additional, Nowak, T., additional, Lin, R., additional, Costamagna, G., additional, and Spada, C., additional

Published
2023
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12. Benefits from a computer-aided detection device in colonoscopy (ACCENDO-COLO) – an interim analysis of an italian multicenter randomized clinical trial

Author

Salvi, D., additional, Pecere, S., additional, Cesaro, P., additional, Ciuffini, C., additional, Milluzzo, S. M., additional, Quadarella, A., additional, Piccirelli, S., additional, Pesatori, E. V., additional, Belluardo, N., additional, Ferrari, C., additional, Olivari, N., additional, Codazzi, M., additional, Gerardi, V., additional, Grazioli, L. Minelli, additional, Barbaro, F., additional, Papparella, L. G., additional, Petruzziello, L., additional, Costamagna, G., additional, and Spada, C., additional

Published
2023
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14. OC.07.1 BENEFITS FROM A COMPUTER-AIDED DETECTION DEVICE IN COLONOSCOPY (ACCENDO-COLO) – AN INTERIM ANALYSIS OF AN ITALIAN MULTICENTER RANDOMIZED CLINICAL TRIAL

Author

Salvi, D., primary, Pecere, S., additional, Cesaro, P., additional, Ciuffini, C., additional, Milluzzo, S.M., additional, Quadarella, A., additional, Piccirelli, S., additional, Pesatori, E., additional, Belluardo, N., additional, Olivari, N., additional, Codazzi, M., additional, Minelli Grazioli, L., additional, Gerardi, V., additional, Ferrari, C., additional, Barbaro, F., additional, Papparella, L., additional, Petruzziello, L., additional, Costamagna, G., additional, and Spada, C., additional

Published
2023
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15. PC.01.1 ARTIFICIAL INTELLIGENCE-ASSISTED SMALL BOWEL CAPSULE ENDOSCOPY READING IN PATIENTS WITH SUSPECTED SMALL BOWEL BLEEDING

Author

Piccirelli, S., primary, Hassan, C., additional, Ferrari, C., additional, Toth, E., additional, Gonzalez-Suarez, B., additional, Keuchel, M., additional, Mcalindon, M., additional, Finta, A., additional, Rosztoczy, A., additional, Dray, X., additional, Salvi, D., additional, Riccioni, M.E., additional, Benamouzig, R., additional, Chattree, A., additional, Saurin, J.C., additional, Humphries, A., additional, Despott, E.J., additional, Murino, A., additional, Wurm Johansson, G., additional, Giordano, A., additional, Baltes, P., additional, Sidhu, R., additional, Szalai, M., additional, Helle, K., additional, Nemeth, A., additional, Nowak, T., additional, Lin, R., additional, Costamagna, G., additional, and Spada, C., additional

Published
2023
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18. Analysis of noise annoyance complaints in the city of Milan, Italy

Author

Zambon, G, Muchetti, S, Salvi, D, Angelini, F, Brambilla, G, Benocci, R, Zambon G., Muchetti S. S., Salvi D., Angelini F., Brambilla G., Benocci R., Zambon, G, Muchetti, S, Salvi, D, Angelini, F, Brambilla, G, Benocci, R, Zambon G., Muchetti S. S., Salvi D., Angelini F., Brambilla G., and Benocci R.

Abstract

The paper describes the analysis of noise annoyance complaints submitted by citizens to the Municipality of Milan, Italy, from years 2000 to 2015. These complaints have been organized in a database and analysed according to: i) types of noise sources (technical facilities, music, transport infrastructures, etc.), ii) activities (retail and catering businesses, production, service sector, etc.) and iii) outcomes of the complaints inspection by local authorities. In addition, by means of a Geographic Information System (GIS) software, the spatial distribution of complaints has been determined according to the noise source type and activities, including also a geo-statistical representation by complaints density maps. The results show that, despite the dominant noise source in urban areas is mainly the road traffic, the other noises, such as those from industrial facilities, constructions and social activities (parties, fairs and open air markets, residential noise, etc.), are perceived as more disturbing. Since 2007, the number of noise complaints (about 100-150 complaints/year) is almost constant across the years. However, these complaints are expected to increase due to the growing and spreading of leisure activities, malls, exhibition centres and event venues, observed for the years 2014-2015.

Published
2020

19. Spatial analysis and temporal trend of registered noise complaints in the city of Milan, Italy

Author

Benocci, R, Muchetti, S, Salvi, D, Angelini, F, Brambilla, G, Zambon, G, Benocci R., Muchetti S. S., Salvi D., Angelini F., Brambilla G., Zambon G., Benocci, R, Muchetti, S, Salvi, D, Angelini, F, Brambilla, G, Zambon, G, Benocci R., Muchetti S. S., Salvi D., Angelini F., Brambilla G., and Zambon G.

Abstract

Noise complaints, expressed by individuals or a group of people, are the outcome of a complex behaviour depending not only on the noise exposure and its evoked annoyance, but also on other factors such as socio-economic ones. Noise annoyance has significant impacts on the quality of life and health of inhabitants, as well as social cohesion. Thus, noise complaints are a very important issue to tackle for national and local policy makers and for all stakeholders involved in planning and management of noise mitigation actions. Within the above framework, the present study describes the analysis of noise complaints submitted by citizens to the municipality of Milan, Italy, from years 2000 to 2015. These complaints have been organized in a database and analyzed considering: i) types of noise source (technical facilities, music, transport infrastructures, etc.); ii) business/leisure activities (retail and catering businesses, production, service sector, etc.) and iii) outcomes of the complaints inspection by local authorities. In addition, by means of a GIS software, the territorial distribution of noise complaints has been determined according to the noise source category and disturbing activity. This analysis includes also a geo-statistical representation by density maps. The results show that, even though road traffic is the dominant noise source in residential and urban areas, the perception of other noises, such as those from industrial facilities, civil construction and social activities (parties, fairs and open air markets, residential noise, etc.), is perceived as more annoying. The results show that since 2007 the number of noise complaints (about 100-150 complaints/year) remains almost constant across the years. However, the spreading of leisure activities, malls, exhibition centers and venues, as observed for the years 2014-2015, would most likely grow them even more. This outcome can assist the local authority in the management of the activities in order to r

Published
2020

27. Prevalence of Gastrointestinal Symptoms in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Results of the Prospective Controlled Multinational GI-COVID-19 Study

Author

Marasco, G., Cremon, C., Barbaro, M. R., Salvi, D., Cacciari, G., Kagramanova, A., Bordin, D., Drug, V., Miftode, E., Fusaroli, P., Mohamed, S. Y., Ricci, C., Bellini, M., Rahman, M. M., Melcarne, L., Santos, J., Lobo, B., Bor, S., Yapali, S., Akyol, D., Sapmaz, F. P., Urun, Y. Y., Eskazan, T., Celebi, A., Kacmaz, H., Ebik, B., Binicier, H. C., Bugdayci, M. S., Yagci, M. B., Pullukcu, H., Kaya, B. Y., Tureyen, A., Hatemi, I., Koc, E. S., Sirin, G., Caliskan, A. R., Bengi, G., Alis, E. E., Lukic, S., Trajkovska, M., Hod, K., Dumitrascu, D., Pietrangelo, A., Corradini, E., Simren, M., Sjolund, J., Tornkvist, N., Ghoshal, U. C., Kolokolnikova, O., Colecchia, A., Serra, J., Maconi, G., De Giorgio, R., Danese, S., Portincasa, P., Di Stefano, M., Maggio, M., Philippou, E., Lee, Y. Y., Venturi, A., Borghi, C., Zoli, M., Gionchetti, P., Viale, P., Stanghellini, V., Barbara, G., Piacentini, A., Shengelia, M., Vechorko, V., Cardamone, C., Rosei, C. A., Pancetti, A., Rettura, F., Pedrosa, M., Campoli, C., Mijac, D., Korac, M., Karic, U., Markovic, A., Najdeski, A., Nikolova, D., Dimzova, M., Lior, O., Shinhar, N., Perelmutter, O., Ringel, Y., Sabo, C. M., Chis, A., Bonucchi, G., Caio, G. P. I., Ghirardi, C., Marziani, B., Rizzello, B., Aguilar, A., Capogreco, A., Aghemo, A., Di Paolo, D. M., Marconi, G., Di Sabatino, A., Tagliaferri, S., Naves, J. E., Galli, A., Dragoni, G., Nedelcu, L., Mauloni, P. A., Del Vecchio, S., Rotondo, L., Capuani, F., Montanari, D., Palombo, F., Paone, C., Mastel, G., Fontana, C., Bellacosa, L., Cogliandro, R. F., Marasco, Giovanni, Cremon, Cesare, Barbaro, Maria Raffaella, Salvi, Daniele, Cacciari, Giulia, Kagramanova, Anna, Bordin, Dmitry, Drug, Vasile, Miftode, Edgidia, Fusaroli, Pietro, Mohamed, Salem Youssef, Ricci, Chiara, Bellini, Massimo, Rahman, M Masudur, Melcarne, Luigi, Santos, Javier, Lobo, Beatriz, Bor, Serhat, Yapali, Suna, Akyol, Deniz, Sapmaz, Ferdane Pirincci, Urun, Yonca Yilmaz, Eskazan, Tugce, Celebi, Altay, Kacmaz, Huseyin, Ebik, Berat, Binicier, Hatice Cilem, Bugdayci, Mehmet Sait, Yağcı, Munkhtsetseg Banzragch, Pullukcu, Husnu, Kaya, Berrin Yalınba, Tureyen, Ali, Hatemi, İbrahim, Koc, Elif Sitre, Sirin, Goktug, Calıskan, Ali Riza, Bengi, Goksel, Alıs, Esra Ergun, Lukic, Snezana, Trajkovska, Meri, Hod, Keren, Dumitrascu, Dan, Pietrangelo, Antonello, Corradini, Elena, Simren, Magnu, Sjolund, Jessica, Tornkvist, Navkiran, Ghoshal, Uday C, Kolokolnikova, Olga, Colecchia, Antonio, Serra, Jordi, Maconi, Giovanni, De Giorgio, Roberto, Danese, Silvio, Portincasa, Pietro, Di Stefano, Michele, Maggio, Marcello, Philippou, Elena, Lee, Yeong Yeh, Venturi, Alessandro, Borghi, Claudio, Zoli, Marco, Gionchetti, Paolo, Viale, Pierluigi, Stanghellini, Vincenzo, and Barbara, Giovanni

Subjects
Male, medicine.medical_specialty, Settore MED/17 - Malattie Infettive, Coronavirus disease 2019 (COVID-19), Nausea, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), diarrhea, Disease, Gastrointestinal Symptoms, COVID-19, Acute Respiratory Syndrome, GI-COVID-19, NO, Russia, Manifestations, Interviews as Topic, Rating scale, Internal medicine, Surveys and Questionnaires, parasitic diseases, medicine, Prevalence, Humans, In patient, Prospective Studies, Respiratory system, Settore MED/12 - Gastroenterologia, Hepatology, business.industry, SARS-CoV-2, pandemic, Gastroenterology, COVID-19, Middle Aged, gastrointestinal, Gastroenteritis, Europe, Hospital admission, Egypt, Female, medicine.symptom, business, human activities
Abstract

INTRODUCTION: Gastrointestinal (GI) symptoms in coronavirus-19 disease (COVID-19) have been reported with great variability and without standardization. In hospitalized patients, we aimed to evaluate the prevalence of GI symptoms, factors associated with their occurrence, and variation at 1 month. METHODS: The GI-COVID-19 is a prospective, multicenter, controlled study. Patients with and without COVID-19 diagnosis were recruited at hospital admission and asked for GI symptoms at admission and after 1 month, using the validated Gastrointestinal Symptom Rating Scale questionnaire. RESULTS: The study included 2036 hospitalized patients. A total of 871 patients (575 COVID+ and 296 COVID-) were included for the primary analysis. GI symptoms occurred more frequently in patients with COVID-19 (59.7%; 343/575 patients) than in the control group (43.2%; 128/296 patients) (P < 0.001). Patients with COVID-19 complained of higher presence or intensity of nausea, diarrhea, loose stools, and urgency as compared with controls. At a 1-month follow-up, a reduction in the presence or intensity of GI symptoms was found in COVID-19 patients with GI symptoms at hospital admission. Nausea remained increased over controls. Factors significantly associated with nausea persistence in COVID-19 were female sex, high body mass index, the presence of dyspnea, and increased C-reactive protein levels. DISCUSSION: The prevalence of GI symptoms in hospitalized patients with COVID-19 is higher than previously reported. Systemic and respiratory symptoms are often associated with GI complaints. Nausea may persist after the resolution of COVID-19 infection., Fondazione Cassa di Risparmio in Bologna; Italian Ministry of Education, University and Research; Fondazione del Monte di Bologna e Ravenna [SC1-BHC-01-2019]; European Grant H2020, DISCOvERIE [SC1-BHC-01-2019]; Italian Ministry of Health [Ricerca Finalizzata GR-2018-12367062], G.B. contribution to this research was permitted in part by funding from Fondazione Cassa di Risparmio in Bologna; the ItalianMinistry of Education, University and Research; and Fondazione del Monte di Bologna e Ravenna and European Grant H2020, DISCOvERIE, SC1-BHC-01-2019. M.R.B. is a recipient of a grant from the Italian Ministry of Health (Ricerca Finalizzata GR-2018-12367062). None of the funding organizations have had any role in the design and conduct of the study; in the collection, management, and analysis of the data; or in the preparation, review, and approval of the article.

Published
2022

28. Status of the largest extant population of the critically endangered Aeolian lizard Podarcis raffonei (Capo Grosso, Vulcano island)

Author

Ficetola, G. F., Silva-Rocha, I., Carretero, M. A., Vignoli, L., Sacchi, R., Melotto, A., Scali, S., Salvi, D., Ficetola, G. F., Silva-Rocha, I., Carretero, M. A., Vignoli, L., Sacchi, R., Melotto, A., Scali, S., and Salvi, D.

Subjects
Topography, European People, Conservation Biology, Invasive Species, Medicine and Health Sciences, Ethnicities, Body Size, Conservation of Natural Resource, Reptile Genomics, Phylogeny, Conservation Science, Islands, Eukaryota, Lizards, Genomics, Squamates, Italian People, Phenotype, Vertebrates, Medicine, Anatomy, Research Article, Conservation of Natural Resources, Evolutionary Processes, Science, Island, Throat, Species Colonization, Genetics, Animals, Species Extinction, Landforms, Evolutionary Biology, Animal, Ecology and Environmental Sciences, Organisms, Biology and Life Sciences, Reptiles, Geomorphology, Animal Genomics, Amniotes, People and Places, Earth Sciences, Lizard, Population Groupings, Zoology, Neck
Abstract

The Aeolian wall lizard Podarcis raffonei is an island endemic that survives only on three tiny islets, and on the Capo Grosso peninsula of the Vulcano island, thus is among the European vertebrates with the smallest range and one of the most threatened by extinction. This species is declining due to competition and hybridization with the non-native lizard Podarcis siculus, but a regular monitoring program is lacking. Here we assessed the size and status of the Capo Grosso population of P. raffonei on Vulcano. In September 2015 we captured 30 individuals showing the typical brown phenotype of P. raffonei, while one single male showed a green phenotype, apparently intermediate between P. raffonei and the non-native Podarcis siculus. In May 2017, only 47% of 131 individuals showed the typical brown phenotype (P. raffonei-like) and 53% showed the green phenotype (P. siculus-like). Based on N-mixture models and removal sampling the estimated size of the Capo Grosso population was of 800-1300 individuals in 2017, being similar to 2015; available data suggest that the total range of the species could be as small as 2 ha. The frequency of individuals with the typical P. raffonei phenotype dramatically dropped between two samplings with a parallel increase of individuals displaying the green phenotype. Observation on outdoor captive-bred individuals demonstrates plasticity for colouration in P. raffonei individuals from Capo Grosso, with several individuals showing the typical brown pattern in September 2017 and a green pattern in March 2021. Non-exclusive hypotheses, including hybridization with P. siculus and plasticity in colour pattern of P. raffonei, are discussed to explain the phenotypic shifts of the P. raffonei population of Capo Grosso. While genomic evidence is required to reach conclusions and investigate eventual hybridization, it is urgent to undertake a programme for the monitoring and management of this lizard.

Published
2021

34. N-mixture models reliably estimate the abundance of small vertebrates

Author

Ficetola, G, Barzaghi, B, Melotto, A, Muraro, M, Lunghi, E, Canedoli, C, Lo Parrino, E, Nanni, V, Silva-Rocha, I, Urso, A, Carretero, M, Salvi, D, Scali, S, Scari, G, Pennati, R, Andreone, F, Manenti, R, Ficetola G. F., Barzaghi B., Melotto A., Muraro M., Lunghi E., Canedoli C., Lo Parrino E., Nanni V., Silva-Rocha I., Urso A., Carretero M. A., Salvi D., Scali S., Scari G., Pennati R., Andreone F., Manenti R., Ficetola, G, Barzaghi, B, Melotto, A, Muraro, M, Lunghi, E, Canedoli, C, Lo Parrino, E, Nanni, V, Silva-Rocha, I, Urso, A, Carretero, M, Salvi, D, Scali, S, Scari, G, Pennati, R, Andreone, F, Manenti, R, Ficetola G. F., Barzaghi B., Melotto A., Muraro M., Lunghi E., Canedoli C., Lo Parrino E., Nanni V., Silva-Rocha I., Urso A., Carretero M. A., Salvi D., Scali S., Scari G., Pennati R., Andreone F., and Manenti R.

Abstract

Accurate measures of species abundance are essential to identify conservation strategies. N-mixture models are increasingly used to estimate abundance on the basis of species counts. In this study we tested whether abundance estimates obtained using N-mixture models provide consistent results with more traditional approaches requiring capture (capture-mark recapture and removal sampling). We focused on endemic, threatened species of amphibians and reptiles in Italy, for which accurate abundance data are needed for conservation assessments: The Lanza's Alpine salamander Salamandra lanzai, the Ambrosi's cave salamander Hydromantes ambrosii and the Aeolian wall lizard Podarcis raffonei. In visual counts, detection probability was variable among species, ranging between 0.14 (Alpine salamanders) and 0.60 (cave salamanders). For all the species, abundance estimates obtained using N-mixture models showed limited differences with the ones obtained through capture-mark-recapture or removal sampling. The match was particularly accurate for cave salamanders in sites with limited abundance and for lizards, nevertheless non-incorporating heterogeneity of detection probability increased bias. N-mixture models provide reliable abundance estimates that are comparable with the ones of more traditional approaches, and offer additional advantages such as a smaller sampling effort and no need of manipulating individuals, which in turn reduces the risk of harming animals and spreading diseases.

Published
2018

40. Environmental temperatures shape thermal physiology as well as diversification and genome-wide substitution rates in lizards

Author

Garcia-Porta, J. Irisarri, I. Kirchner, M. Rodríguez, A. Kirchhof, S. Brown, J.L. MacLeod, A. Turner, A.P. Ahmadzadeh, F. Albaladejo, G. Crnobrnja-Isailovic, J. De la Riva, I. Fawzi, A. Galán, P. Göçmen, B. Harris, D.J. Jiménez-Robles, O. Joger, U. Jovanović Glavaš, O. Karış, M. Koziel, G. Künzel, S. Lyra, M. Miles, D. Nogales, M. Oğuz, M.A. Pafilis, P. Rancilhac, L. Rodríguez, N. Rodríguez Concepción, B. Sanchez, E. Salvi, D. Slimani, T. S’khifa, A. Qashqaei, A.T. Žagar, A. Lemmon, A. Moriarty Lemmon, E. Carretero, M.A. Carranza, S. Philippe, H. Sinervo, B. Müller, J. Vences, M. Wollenberg Valero, K.C.

Abstract

Climatic conditions changing over time and space shape the evolution of organisms at multiple levels, including temperate lizards in the family Lacertidae. Here we reconstruct a dated phylogenetic tree of 262 lacertid species based on a supermatrix relying on novel phylogenomic datasets and fossil calibrations. Diversification of lacertids was accompanied by an increasing disparity among occupied bioclimatic niches, especially in the last 10 Ma, during a period of progressive global cooling. Temperate species also underwent a genome-wide slowdown in molecular substitution rates compared to tropical and desert-adapted lacertids. Evaporative water loss and preferred temperature are correlated with bioclimatic parameters, indicating physiological adaptations to climate. Tropical, but also some populations of cool-adapted species experience maximum temperatures close to their preferred temperatures. We hypothesize these species-specific physiological preferences may constitute a handicap to prevail under rapid global warming, and contribute to explaining local lizard extinctions in cool and humid climates. © 2019, The Author(s).

Published
2019

42. Attività produttive ed economia del cratere

Author

Pierantoni I., Salvi D., Sargolini M., Esposti, R., Baldoni, E., Coderoni, Silvia, Coderoni S. (ORCID:0000-0001-8751-7376), Pierantoni I., Salvi D., Sargolini M., Esposti, R., Baldoni, E., Coderoni, Silvia, and Coderoni S. (ORCID:0000-0001-8751-7376)

Abstract

L’obiettivo di questo capitolo è produrre una prima analisi dell’impatto del sisma del 2016 sul sistema produttivo del territorio colpito, limitatamente alle Marche (da qui in poi, solo “cratere”). Sebbene siano ormai passati più di due anni, si tratta comunque di un primo e provvisorio tentativo vista la difficoltà nel reperimento nonché aggiornamento dei dati. Oltre a quantificare l’impatto, tuttavia, l’obiettivo dell’analisi è anche quello di qualificarlo. Non solo esprimere il “quanto” ma anche il “dove” e il “come” nella convinzione che, data anche la vastità del cratere, l’impatto del sisma sia stato notevolmente differente tra i diversi territori e settori.

Published
2019

44. Micronucleus test on Triturus carnifex as a tool for environmental biomonitoring

Author

Udroiu I., Sgura A., BOLOGNA, Marco Alberto, D'Amen M., Salvi D., Ruzza A., ANTOCCIA, Antonio, Tanzarella C., VIGNOLI, LEONARDO, Udroiu, Ion, Sgura, Antonella, Vignoli, Leonardo, Bologna, Marco Alberto, D'Amen, M, Salvi, D, Ruzza, A, Antoccia, A, Tanzarella, C., Sgura, A, Vignoli, L, Bologna, Ma, Udroiu, I, Antoccia, Antonio, Udroiu, I., Sgura, A., D'Amen, M., Salvi, D., and Ruzza, A.

Subjects
Amphibian, Biomonitoring, Genotoxicity, Animals, Environmental Monitoring, Fresh Water, Gills, Italy, Larva, Metals, Heavy, Micronucleus Tests, Ponds, Triturus, Water Pollutants, Chemical, Health, Toxicology and Mutagenesis, Epidemiology, Genetics (clinical), Medicine (all), animal structures, Chemical, Water Pollutants, Toxicology and Mutagenesis, genotoxicity, fungi, Heavy, Metals, Health, biomonitoring, amphibian
Abstract

The amphibian micronucleus test has been widely used during the last 30 years to test the genotoxic properties of several chemicals and as a tool for ecogenotoxic monitoring. The vast majority of these studies were performed on peripheral blood of urodelan larvae and anuran tadpoles and to a lesser extent adults were also used. In this study, we developed protocols for measuring micronuclei in adult shed skin cells and larval gill cells of the Italian crested newt (Triturus carnifex). Amphibians were collected from ponds in two protected areas in Italy that differed in their radon content. Twenty-three adult newts and 31 larvae were captured from the radon-rich pond, while 20 adults and 27 larvae were taken from the radon-free site. The animals were brought to the laboratory and the micronucleus test was performed on peripheral blood and shed skins taken from the adults and on larval gills. Samples from the radon-rich site showed micronucleus frequencies higher than those from the radon-free site and the difference was statistically significant in gill cells (P < 0.00001). Moreover, the larval gills seem to be more sensitive than the adult tissues. This method represents an easy (and noninvasive in the case of the shed skin) application of the micronucleus assay that can be useful for environmental studies in situ. Environ. Mol. Mutagen. 56:412-417, 2015. (c) 2014 Wiley Periodicals, Inc.

Published
2015

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