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Your search keyword '"Salsman, Vita S."' showing total 19 results
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19 results on '"Salsman, Vita S."'

1. Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial

Author

Hegde, Meenakshi, Navai, Shoba, DeRenzo, Christopher, Joseph, Sujith K., Sanber, Khaled, Wu, Mengfen, Gad, Ahmed Z., Janeway, Katherine A., Campbell, Matthew, Mullikin, Dolores, Nawas, Zeid, Robertson, Catherine, Mathew, Pretty R., Zhang, Huimin, Mehta, Birju, Bhat, Raksha R., Major, Angela, Shree, Ankita, Gerken, Claudia, Kalra, Mamta, Chakraborty, Rikhia, Thakkar, Sachin G., Dakhova, Olga, Salsman, Vita S., Grilley, Bambi, Lapteva, Natalia, Gee, Adrian, Dotti, Gianpietro, Bao, Riyue, Salem, Ahmed Hamed, Wang, Tao, Brenner, Malcolm K., Heslop, Helen E., Wels, Winfried S., Hicks, M. John, Gottschalk, Stephen, and Ahmed, Nabil

Published
2024
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2. Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models

Author

Zhang, Huiyuan, Du, Yuchen, Qi, Lin, Xiao, Sophie, Braun, Frank K., Kogiso, Mari, Huang, Yulun, Huang, Frank, Abdallah, Aalaa, Suarez, Milagros, Karthick, Sekar, Ahmed, Nabil M., Salsman, Vita S., Baxter, Patricia A., Su, Jack M., Brat, Daniel J., Hellenbeck, Paul L., Teo, Wan-Yee, Patel, Akash J., and Li, Xiao-Nan

Published
2023
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3. CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression

Author

Fousek, Kristen, Watanabe, Junji, Joseph, Sujith K., George, Ann, An, Xingyue, Byrd, Tiara T., Morris, Jessica S., Luong, Annie, Martínez-Paniagua, Melisa A., Sanber, Khaled, Navai, Shoba A., Gad, Ahmed Z., Salsman, Vita S., Mathew, Pretty R., Kim, Hye Na, Wagner, Dimitrios L., Brunetti, Lorenzo, Jang, Albert, Baker, Matthew L., Varadarajan, Navin, Hegde, Meenakshi, Kim, Yong-Mi, Heisterkamp, Nora, Abdel-Azim, Hisham, and Ahmed, Nabil

Published
2021
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4. Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma

Author

Hegde, Meenakshi, Joseph, Sujith K., Pashankar, Farzana, DeRenzo, Christopher, Sanber, Khaled, Navai, Shoba, Byrd, Tiara T., Hicks, John, Xu, Mina L., Gerken, Claudia, Kalra, Mamta, Robertson, Catherine, Zhang, Huimin, Shree, Ankita, Mehta, Birju, Dakhova, Olga, Salsman, Vita S., Grilley, Bambi, Gee, Adrian, Dotti, Gianpietro, Heslop, Helen E., Brenner, Malcolm K., Wels, Winfried S., Gottschalk, Stephen, and Ahmed, Nabil

Published
2020
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5. Glioma cells display complex cell surface topographies that resist the actions of cytolytic effector lymphocytes.

Author

Hoa, Neil, Ge, Lisheng, Kuznetsov, Yurii, McPherson, Alex, Cornforth, Andrew N, Pham, Jimmy TH, Myers, Michael P, Ahmed, Nabil, Salsman, Vita S, Lamb, Lawrence S, Bowersock, Joscelyn E, Hu, Yuanjie, Zhou, Yi-Hong, and Jadus, Martin R

Subjects
Killer Cells, Lymphokine-Activated, T-Lymphocytes, Cytotoxic, Cell Line, Tumor, Cell Membrane, Microvilli, Animals, Humans, Rats, Glioma, Microscopy, Confocal, Microscopy, Electron, Transmission, Microscopy, Atomic Force, Fluorescent Antibody Technique, Cytotoxicity, Immunologic, Tumor Escape, Killer Cells, Lymphokine-Activated, T-Lymphocytes, Cytotoxic, Cell Line, Tumor, Microscopy, Confocal, Electron, Transmission, Atomic Force, Cytotoxicity, Immunologic, Brain Disorders, Cancer, Neurosciences, Brain Cancer, Rare Diseases, Immunology
Abstract

Gliomas are invasive cancers that resist all forms of attempted therapy. Immunotherapy using Ag-pulsed dendritic cells has improved survival in some patients. We present evidence that another level of complexity may also contribute to lack of responses by the lymphocytes toward gliomas. Atomic force microscopy of four different glioma types-human U251 and rat T9 and F98 glioma cells, including freshly isolated human glioblastoma multiforme neurosphere cultures (containing "stem cell-like cells")-revealed a complex surface topography with numerous microvilli and filopodia. These structures were not found on other cell types. Electron microscopy and immunofluorescence microscopy of glioma cells confirmed that microvilli are present. U251 cells with microvilli resisted the cytolytic actions of different human effector cells, (lymphokine-activated killer cells, γδ T cells, conventional CTLs, and chimeric Ag-receptor-redirected T cells) better than their nonmicrovilli-expressing counterparts. Killer lymphocytes released perforin, which was detected within the glioma's microvilli/filopodia, indicating these structures can receive the cytolytic effector molecules, but cytotoxicity is suboptimal. Air-dried gliomas revealed nodes within the microvilli/filopodia. The microvilli that penetrated 0.4-μm transwell chamber's pores resisted the actions of CTLs and physical damage. Those nodelike structures may represent a compartmentalization that resists physical damage. These microvilli may play multiple roles in glioma biology, such as invasion and resistance to lymphocyte-mediated killing.

Published
2010

6. A homing system targets therapeutic T cells to brain cancer

Author

Samaha, Heba, Pignata, Antonella, Fousek, Kristen, Ren, Jun, Lam, Fong W., Stossi, Fabio, Dubrulle, Julien, Salsman, Vita S., Krishnan, Shanmugarajan, Hong, Sung-Ha, Baker, Matthew L., Shree, Ankita, Gad, Ahmed Z., Shum, Thomas, Fukumura, Dai, Byrd, Tiara T., Mukherjee, Malini, Marrelli, Sean P., Orange, Jordan S., Joseph, Sujith K., Sorensen, Poul H., Taylor, Michael D., Hegde, Meenakshi, Mamonkin, Maksim, Jain, Rakesh K., El-Naggar, Shahenda, and Ahmed, Nabil

Published
2018
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8. Supplementary Methods and Data from TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer

Author

Byrd, Tiara T., primary, Fousek, Kristen, primary, Pignata, Antonella, primary, Szot, Christopher, primary, Samaha, Heba, primary, Seaman, Steven, primary, Dobrolecki, Lacey, primary, Salsman, Vita S., primary, Oo, Htoo Zarni, primary, Bielamowicz, Kevin, primary, Landi, Daniel, primary, Rainusso, Nino, primary, Hicks, John, primary, Powell, Suzanne, primary, Baker, Matthew L., primary, Wels, Winfried S., primary, Koch, Joachim, primary, Sorensen, Poul H., primary, Deneen, Benjamin, primary, Ellis, Matthew J., primary, Lewis, Michael T., primary, Hegde, Meenakshi, primary, Fletcher, Bradley S., primary, St. Croix, Brad, primary, and Ahmed, Nabil, primary

Published
2023
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9. Figure S3 from TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer

Author

Byrd, Tiara T., primary, Fousek, Kristen, primary, Pignata, Antonella, primary, Szot, Christopher, primary, Samaha, Heba, primary, Seaman, Steven, primary, Dobrolecki, Lacey, primary, Salsman, Vita S., primary, Oo, Htoo Zarni, primary, Bielamowicz, Kevin, primary, Landi, Daniel, primary, Rainusso, Nino, primary, Hicks, John, primary, Powell, Suzanne, primary, Baker, Matthew L., primary, Wels, Winfried S., primary, Koch, Joachim, primary, Sorensen, Poul H., primary, Deneen, Benjamin, primary, Ellis, Matthew J., primary, Lewis, Michael T., primary, Hegde, Meenakshi, primary, Fletcher, Bradley S., primary, St. Croix, Brad, primary, and Ahmed, Nabil, primary

Published
2023
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10. Data from TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer

Author

Byrd, Tiara T., primary, Fousek, Kristen, primary, Pignata, Antonella, primary, Szot, Christopher, primary, Samaha, Heba, primary, Seaman, Steven, primary, Dobrolecki, Lacey, primary, Salsman, Vita S., primary, Oo, Htoo Zarni, primary, Bielamowicz, Kevin, primary, Landi, Daniel, primary, Rainusso, Nino, primary, Hicks, John, primary, Powell, Suzanne, primary, Baker, Matthew L., primary, Wels, Winfried S., primary, Koch, Joachim, primary, Sorensen, Poul H., primary, Deneen, Benjamin, primary, Ellis, Matthew J., primary, Lewis, Michael T., primary, Hegde, Meenakshi, primary, Fletcher, Bradley S., primary, St. Croix, Brad, primary, and Ahmed, Nabil, primary

Published
2023
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12. Retraction Note: A homing system targets therapeutic T cells to brain cancer

Author

Samaha, Heba, Pignata, Antonella, Fousek, Kristen, Ren, Jun, Lam, Fong W., Stossi, Fabio, Dubrulle, Julien, Salsman, Vita S., Krishnan, Shanmugarajan, Hong, Sung-Ha, Baker, Matthew L., Shree, Ankita, Gad, Ahmed Z., Shum, Thomas, Fukumura, Dai, Byrd, Tiara T., Mukherjee, Malini, Marrelli, Sean P., Orange, Jordan S., Joseph, Sujith K., Sorensen, Poul H., Taylor, Michael D., Hegde, Meenakshi, Mamonkin, Maksim, Jain, Rakesh K., El-Naggar, Shahenda, and Ahmed, Nabil

Published
2019
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13. A subset of cytotoxic effector memory T cells enhances CAR T cell efficacy in a model of pancreatic ductal adenocarcinoma

Author

Konduri, Vanaja, primary, Joseph, Sujith K., additional, Byrd, Tiara T., additional, Nawas, Zeid, additional, Vazquez-Perez, Jonathan, additional, Hofferek, Colby J., additional, Halpert, Matthew M., additional, Liu, Dongliang, additional, Liang, Zhengdong, additional, Baig, Yunyu, additional, Salsman, Vita S., additional, Oyewole-Said, Damilola, additional, Tsimelzon, Anna, additional, Burns, Briana A., additional, Chen, Changyi, additional, Levitt, Jonathan M., additional, Yao, Qizhi, additional, Ahmed, Nabil M., additional, Hegde, Meenakshi, additional, and Decker, William K., additional

Published
2021
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14. CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression

Author

Fousek, Kristen, primary, Watanabe, Junji, additional, Joseph, Sujith K., additional, George, Ann, additional, An, Xingyue, additional, Byrd, Tiara T., additional, Morris, Jessica S., additional, Luong, Annie, additional, Martínez-Paniagua, Melisa A., additional, Sanber, Khaled, additional, Navai, Shoba A., additional, Gad, Ahmed Z., additional, Salsman, Vita S., additional, Mathew, Pretty R., additional, Kim, Hye Na, additional, Wagner, Dimitrios L., additional, Brunetti, Lorenzo, additional, Jang, Albert, additional, Baker, Matthew L., additional, Varadarajan, Navin, additional, Hegde, Meenakshi, additional, Kim, Yong-Mi, additional, Heisterkamp, Nora, additional, Abdel-Azim, Hisham, additional, and Ahmed, Nabil, additional

Published
2020
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15. TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer

Author

Byrd, Tiara T., primary, Fousek, Kristen, additional, Pignata, Antonella, additional, Szot, Christopher, additional, Samaha, Heba, additional, Seaman, Steven, additional, Dobrolecki, Lacey, additional, Salsman, Vita S., additional, Oo, Htoo Zarni, additional, Bielamowicz, Kevin, additional, Landi, Daniel, additional, Rainusso, Nino, additional, Hicks, John, additional, Powell, Suzanne, additional, Baker, Matthew L., additional, Wels, Winfried S., additional, Koch, Joachim, additional, Sorensen, Poul H., additional, Deneen, Benjamin, additional, Ellis, Matthew J., additional, Lewis, Michael T., additional, Hegde, Meenakshi, additional, Fletcher, Bradley S., additional, St. Croix, Brad, additional, and Ahmed, Nabil, additional

Published
2018
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17. Crosstalk between Medulloblastoma Cells and Endothelium Triggers a Strong Chemotactic Signal Recruiting T Lymphocytes to the Tumor Microenvironment

Author

Salsman, Vita S., primary, Chow, Kevin K. H., additional, Shaffer, Donald R., additional, Kadikoy, Huseyin, additional, Li, Xiao-Nan, additional, Gerken, Claudia, additional, Perlaky, Laszlo, additional, Metelitsa, Leonid S., additional, Gao, Xiuhua, additional, Bhattacharjee, Meena, additional, Hirschi, Karen, additional, Heslop, Helen E., additional, Gottschalk, Stephen, additional, and Ahmed, Nabil, additional

Published
2011
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19. Immunotherapy for Osteosarcoma: Genetic Modification of T cells Overcomes Low Levels of Tumor Antigen Expression

Author

Ahmed, Nabil, primary, Salsman, Vita S, additional, Yvon, Eric, additional, Louis, Chrystal U, additional, Perlaky, Laszlo, additional, Wels, Winfried S, additional, Dishop, Meghan K, additional, Kleinerman, Eugenie E, additional, Pule, Martin, additional, Rooney, Cliona M, additional, Heslop, Helen E, additional, and Gottschalk, Stephen, additional

Published
2009
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