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7. Venous thromboembolism risk and prophylaxis in hospitalised medically ill patients

Author

Kaynar, Leylagül, Yildirim, Cuma, PANTOJA, Joao, Rocha, Ana, SCHRAMM, Edgar, TIMI, Jorge, STAIKOV, Ivan, BENOV, Haralambi, MIRAZCHIJSKI, Boyko, STATELOV, Evgenii, STOYKOVA, Antoaneta, TODOROV, Radostin, DENNIS, Rodolfo, DURA, Freddy Rafael Mendez, RESTREPO, Hector, ROA, Jairo H., VILLADIEGO, Juan, MALY, Jaroslav, BRABEC, Tomas, GUMULEC, Jaromir, JOCHYMEK, Roman, KELLNEROVA, Ivana, SKARKOVA, Jindra, SLEZAK, Premysl, VIT, Patrik, GOBRAN, Hadi, EL HADDAD, Alaa, RIZK-ALLAH, Mounir, BERGMANN, Jean Francois, ABINADER, Marid, KHOUDIR, Falah Abou, BOYER, Jean-Francois, BRUN, Natacha, CANET, Bernard, COLLARD, Catherine, CORDIER, Christophe, DURROUX, Claire, EMMERICH, Joseph, FRIOCOURT, Patrick, ANDERSON, Frederick A., CHERFI, Lyes, AMMOUR, Dehbia, BOURENANE, Razika, GRAINAT, Nadia, MAAROUF, Abderahmane, SISSAOUI, Abdelhak, GALLUS, Alexander, AYYAR, Venkatraman, CRIMMINS, Denis, GAN, Eng, MCRAE, Simon, SELDON, Michael, SINGH, Bhuwan, MOULA, Kaniz, NAWAZ, Taimor, NAZIMUDDIN, Khwaja, RAHMAN, Saiyeedur, SARKER, Shyamal, BRANDAO, Carlos, COSTA, Jose, MACEDO, Alex, MARINO, Roberto, MENEZES, Paulo, Bergmann, Jean-Francois, Cohen, Alexander T., Tapson, Victor F., Goldhaber, Samuel Z., Kakkar, Ajay K., Deslandes, Bruno, MOUMEN, Abdelrhani, PHILIPPE, Pierre, PROTIN, Yves, QUERE, Isabelle, RIZCALLAH, Marie-Jeanne, BENSCH, Kristina, BENSMANN, Klaus, Dropmann, Axl, Gerold, Dieter, Gussmann, Andreas, Kube, Lutz, Kuster, Stefan, Leupolz, Werner, Neuhaus, Thomas, Nobel, Wolfgang, Pfiel, Sascha, Pleger, Eberhard, Trautmann, Harald, Voigt, Ingo, Liapis, Christos, Antoniadis, Pavlos, Arvanitis, Dimitrios, Bakatsglos, Spyridon, Christakis, Christos, Gerassimidis, Thomas, Kostakis, Alkiviadis, Losonczy, Hajna, Hajna, Bela, Gyani, Eva, Jojart, Istvan, Kecskes, Gabor, Lakatos, Jozsef, Ledniczki, Istvan, Mayer, Klara, Nyuzo, Balint, Zeher, Margit, Agnihotri, Vinod, Balraj, A., Chakraborty, Amiya, Desai, Sanjay, Elangovan, Antony, Goswami, Partha, Rupert, Emmanuel, Toraskar, Kedar, Venkatesh, Kakollu, Gaine, Sean, Costello, Richard, Liston, Richard, Zubieta, Ricardo Martinez, Fematt, Flor Mario Avila, Esponda, Juan Alejandro Baeza, Benitez Maldonado, Daniel R., Serrano, Maricela Escarela, Montalvo, Carlos Lavalle, Marquez, Santa Lopez, Sanchez, Alejandro Quesada, Diaz, Santiago Ramirez, Serrano, Alejandro Tovar, de la Vega, Maria Isabel Villa, Faridi, Salman, Javaid, Mansur, Khan, Farrukh, Malik, Asif Zafar, Sadiq, Muzafaruddin, Musial, Jacek, Biedziuk, Bartlomiej, Gellert, Ryszard, Kosiniau-Kamysz, Andrzey, Kuta, Marcin, Prajs, Zozislav, Sell, Marek, Tadeusz, Kalbarczyk, Witkiewicz, Wojciech, Wysota, Janusz, Franca, Ana, Abreu, Rui, Cartucho, Daniel, Lohmann, Corinna, Moreira, Pedro, Paulino, Aida, Reis, Abilio, Rojao de Morais, Maria Luisa, Tribolet de Abreu, Tiago, Tulbure, Dan, Andrei, Muresan, Christian, Pricop, Ciurea, Mircea, Enachescu, Mihaela, Gostian, Ovidiu, Grintescu, Ioana Marina, Mimor, Ovidiu, Natalia, Hagau, Puiac, Claudiu, Valerica, Stan, Sulimov, Vitalyi Andreevich, Belentsov, Sergey, Eliseeva, Ekaterina, Fridman, Irina, Kazantchian, Perch, Mashtacov, Boris, Redkin, Alexander, Rodoman, Grigory, Shershnev, Vladislav, Zhidkov, Konstantin, Gaspar, Ludovit, Benova, Katarina, Duris, Tibor, Fecik, Juraj, Hajas, Jan, Herman, Oto, Lehotsky, Jan, Macek, Vladimir, Pradova, Viera, Carrascosa, Miguel, Luque, Rafael Cuenca, del Val Gil, Jose, Diaz de Souza, Pedro, Enfedaque, Muriel Alvaro, Gonzalo, Francesc Epelde, Sanchez, Florentino Garcia, Garcia, Guil, Lopez, Luciano, Rodriguez, Jose Antonio Nieto, Mateo Paredes, Ramon, Ramos Rodriguez, Jose Luis, Cantero, Alberto Ruiz, Lorenzo, Pedro Ruiz, Legarre, Angel Luis Samperiz, Clavo Sanchez, Antonio, Bernad, Reina Valle, Vela Moreno, Jeronimo Ramon, Doerffler, Janine, Beer, Jurg, Brunner, Brigitte, Chopard, Pierre, Fischer, Joseph, Ludwig, Christian, Rime, Francis, Salomon, Franco, Ulrich, Munch, Angchaisuksiri, Pantep, Chetanachan, Mariam, Chuamuangphan, Nonlawan, Insiripong, Somchai, Nawarawong, Weerasak, Ben Salah, Afif, Houman, Mohamed Habib, Mohamed, Mnif, Samir, Kammoun, Smiti-Khanfir, Monia, Zouheir, Jerbi, Ongen, Gul, Altintas, Faik, Cirak, Ali Kadri, Demirtas, Nazmi, Erden, Faruk, Guven, Hulya, Halezeroglu, Semih, Karaoglan, Halim, Tereci, Hikmet, Wilmott, Rosalind, Cohen, Alexander, Calvey, Thomas, Cohen, Angela, Gallegos, Nick, Gaminara, Elizabeth, James, Anthony, Jeffreys, Mike, Jowett, Nigel, Keaney, Niall, Kesteven, Patrick, Khan, Zafar, Mallick, Abhiram, Marval, Paul, Parapia, L., Picozzi, Natalie, Praveen, Bandipalyam, Satchi, Gnanam, Valerio, David, Tapson, Victor, Anderson, Fred, Baker, Gennfer, Beaver, Richard, Becker, William, Beckett, Cynthia, Borchardt, Carla, Briggs, Michael, Bruckman, Joseph, Buck, Lisa, Chausow, Alan, Christopulos, Danielle, Cica, Paula, Cody, Jean, Condit, Bruce, Cronin, Sherill, Huang, Wei, BENTAKOUK, Cherif, SIDDIQUI, F. M., OIGMAN, Wille, PAIVA, Marcelo, TANDEITNIK, Liane, BORISOV, Stefan Dimitrov, LALOV, Anton, POSTADZIYAN, Arman, Cysyk, Barbara, Driggers, Steven, Ellis, Paula, Elvenia, Jaeda, Feinbloom, David, Feldman, Mark, Fischer, Marian, Froehlich, James, Frost, Christopher, Galster, Ruth, Geldmeier, Richard, George, Joyce, Glielmi, Vincent, Goodwin, James, Gottlieb, Anita, Gray, Bruce, Harrington, Darrell, Henry, Edwina, Hill, David, Hutchinson, Melissa, Johnson, Juanita, Johnson, Roberta, Kapre, Sheela, Kedzie, Robyn, Kowaloff, Harvey, Krodel, John, Lehman, James, Marshall, Ingeborg, McDaniels, Mary, Middleton, Robert, Mitchell, Phillip, Nelson, Carrie, Netherland, Susan, Ogden, Maureen, Packard, Keith, Poole, Lorie, Radford, Martha, Rathbun, Suman, Roberts, Cathy, Robinson, Margaret, Rollins, David, Rubinate, Donna, Schmidt, Cheryl, Scott, Julia, Slone, Betty, Spyropoulos, Alex, Subramanian, Seshan, Sullivan, Jacqueline, Timmerman, Carman, Vizzard, Carolyn, Wheeler, Connie, White, Diane, White, Nancy, Wright, Joyce, Young, Dereck, SOKOLOV, Krassimir, STEFANOV, Chavdar, TADZHER, Sheri, POSADA, Jose Alfredo, KVASNICKA, Jan, PENKA, Miroslav, VOJTISEK, Petr, EL RAHMAN, Alaa Mahmaud Aba, GORGY, George Sobhy, SHOLKAMY, Sherif, GENAY, Patrick, IBOUANGA, Florent, PLANCHON, Pierre, ZOTZ, Rainer, Kortmann, Bernd, Wolf, Stefan, Domjan, Gyula, Pinjala, Ramakrishna, Connaughton, John, Perez, Fernando Elias Garcia, Yusaf-Shah, Muhammad, Klonowski, Wlodzimierz, Campello, Maria da Gloria Cabral, Constantin, Palivan, Dubrovnaya, Nina, Barta, Peter, Arcelus, Juan, Lobo-Beristain, Jose Luis, Cardenas, Maria Jose Soto, Peter, Jurg, Ghedira, Habib, Dokucu, Ali, Mackie, Peter, Antonacci, Anthony, Caushaj, Philip, Diefendorf, Anne, Gaffey, Joseph, Hernandez, Cecilia, Marney, Terri, Pieske, Marlys, Shutt, Sandra, and Whitehead, Alva

Subjects
Adult, medicine.medical_specialty, Cross-sectional study, Population, Hemorrhage, Risk Assessment, Fibrinolytic Agents, Residence Characteristics, Risk Factors, Intensive care, Odds Ratio, medicine, Humans, Registries, cardiovascular diseases, Healthcare Disparities, Risk factor, education, Intensive care medicine, Aged, Cardiopulmonary disease, Aged, 80 and over, Inpatients, education.field_of_study, business.industry, Contraindications, Age Factors, Venous Thromboembolism, Hematology, Odds ratio, Middle Aged, medicine.disease, Hospitalization, Venous thrombosis, Cross-Sectional Studies, Logistic Models, Treatment Outcome, Health Care Surveys, Practice Guidelines as Topic, Guideline Adherence, Risk assessment, business
Abstract

SummaryLimited data are available regarding the risk for venous thromboembolism (VTE) and VTE prophylaxis use in hospitalised medically ill patients. We analysed data from the global ENDORSE survey to evaluate VTE risk and prophylaxis use in this population according to diagnosis, baseline characteristics, and country. Data on patient characteristics, VTE risk, and prophylaxis use were abstracted from hospital charts. VTE risk and prophylaxis use were evaluated according to the 2004 American College of Chest Physicians (ACCP) guidelines. Multivariable analysis was performed to identify factors associated with use of ACCP-recommended prophylaxis. Data were evaluated for 37,356 hospitalised medical patients across 32 countries. VTE risk varied according to medical diagnosis, from 31.2% of patients with gastrointestinal/hepatobiliary diseases to 100% of patients with acute heart failure, active non-infectious respiratory disease, or pulmonary infection (global rate, 41.5%). Among those at risk for VTE, ACCP-recommended prophylaxis was used in 24.4% haemorrhagic stroke patients and 40–45% of cardiopulmonary disease patients (global rate, 39.5%). Large differences in prophylaxis use were observed among countries. Markers of disease severity, including central venous catheters, mechanical ventilation, and admission to intensive care units, were strongly associated with use of ACCP-recommended prophylaxis. In conclusion, VTE risk varies according to medical diagnosis. Less than 40% of at-risk hospitalised medical patients receive ACCP-recommended prophylaxis. Prophylaxis use appears to be associated with disease severity rather than medical diagnosis. These data support the necessity to improve implementation of available guidelines for evaluating VTE risk and providing prophylaxis to hospitalised medical patients.

Published
2010
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9. Ventricular fibrillation in a patient with exercise-induced anaphylaxis, normal coronary arteries, and a positive ergonovine test

Author

Attenhofer, Christine, Speich, Rudolf, Salomon, Franco, Burkhard, Roger, and Amann, Franz Wolfgang

Subjects
Ventricular fibrillation -- Causes of -- Complications and side effects, Anaphylaxis -- Complications and side effects, Health, Complications and side effects, Causes of
Abstract

Exercise-induced analphylaxis (EIA) is a rare form of physical allergy. Although histamine release is a feature of EIA, and histamine provocation of coronary spasm has been described, serious cardiac arrhythmias [...]

Published
1994

10. Venous Thromboembolism Risk and Prophylaxis in the Acute Care Hospital Setting (ENDORSE Survey) Findings in Surgical Patients

Author

Yildirim, Cuma, Kaynar, Leylagül, Sell, Marek, Tadeusz, Kalbarczyk, Witkiewicz, Wojciech, Wysota, Janusz, Franca, Ana, Abreu, Rui, Cabral Campello, Maria da Gloria, Cartucho, Daniel, Lohmann, Corinna, Moreira, Pedro, Paulino, Aida, Reis, Abilio, Rojao de Morais, Maria Luisa, de Abreu, Tiago Tribolet, Tulbure, Dan, Andrei, Muresan, Christian, Pricop, GRAINAT, Nadia, MAAROUF, Abderahmane, SISSAOUI, Abdelhak, GALLUS, Alexander, AYYAR, Venkatraman, CRIMMINS, Denis, GAN, Eng, MCRAE, Simon, SELDON, Michael, SINGH, Bhuwan, SIDDIQUI, F. M., MOULA, Kaniz, NAWAZ, Taimor, NAZIMUDDIN, Khwaja, RAHMAN, Saiyeedur, ROCHA, Ana, BERGMANN, Jean Francois, ABINADER, Marid, Domjan, Gyula, Gyani, Eva, Mayer, Klara, Garcia Perez, Fernando Elias, Kuta, Marcin, Ciurea, Mircea, Enachescu, Mihaela, Shershnev, Vladislav, Epelde Gonzalo, Francesc, Samperiz Legarre, Angel Luis, Fischer, Joseph, Altintas, Faik, Jowett, Nigel, Kesteven, Patrick, Anderson, Fred, Cysyk, Barbara, George, Joyce, Harrington, Darrell, Rathbun, Suman, SARKER, Shyamal, Kakkar, Ajay K., Cohen, Alexander T., Tapson, Victor F., Bergmann, Jean-Francois, Goldhaber, Samuel, Deslandes, Bruno, Huang, Wei, ANDERSON, Frederick A., CHERFI, Lyes, AMMOUR, Dehbia, BENTAKOUK, Cherif, BOURENANE, Razika, BRANDAO, Carlos, COSTA, Jose, MACEDO, Alex, MARINO, Roberto, MENEZES, Paulo, OIGMAN, Wille, PAIVA, Marcelo, PANTOJA, Joao, SCHRAMM, Edgar, TANDEITNIK, Liane, TIMI, Jorge, BENOV, Haralambi, BORISOV, Stefan Dimitrov, LALOV, Anton, MIRAZCHIJSKI, Boyko, POSTADZIYAN, Arman, SOKOLOV, Krassimir, STATELOV, Evgenii, STEFANOV, Chavdar, STOYKOVA, Antoaneta, TADZHER, Sheri, TODOROV, Radostin, DENNIS, Rodolfo, DURAN, Freddy Rafael Mendez, POSADA, Alfredo, RESTREPO, Hector, ROA, Jairo, VILLADIEGO, Juan, MALY, Jaroslav, BRABEC, Tomas, GUMULEC, Jaromir, JOCHYMEK, Roman, KELLNEROVA, Ivana, KVASNICKA, Jan, PENKA, Miroslav, SKARKOVA, Jindra, SLEZAK, Premysl, VIT, Patrik, VOJTISEK, Petr, GOBRAN, Hadi, EL RAHMAN, Alaa Mahmaud Aba, EL HADDAD, Alaa, GORGY, George Sobhy, RIZK-ALLAH, Mounir, SHOLKAMY, Sherif, ABOU KHOUDIR, Falah, BOYER, Jean-Francois, BRUN, Natacha, CANET, Bernard, COLLARD, Catherine, CORDIER, Christophe, DURROUX, Claire, EMMERICH, Joseph, FRIOCOURT, Patrick, GENAY, Patrick, IBOUANGA, Florent, MOUMEN, Abdelrhani, PHILIPPE, Pierre, PLANCHON, Pierre, PROTIN, Yves, QUERE, Isabelle, RIZCALLAH, Marie-Jeanne, ZOTZ, Rainer, BENSCH, Kristina, BENSMANN, Klaus, DROPMANN, Axl, GEROLD, Dieter, Gussmann, Andreas, Kortmann, Bernd, Kube, Lutz, Kuster, Stefan, Leupolz, Werner, Neuhaus, Thomas, Nobel, Wolfgang, Pfiel, Sascha, Pleger, Eberhard, Trautmann, Harald, Voigt, Ingo, Wolf, Stefan, Antoniadis, Pavlos, Arvanitis, Dimitrios, Bakatsglos, Spyridon, Christakis, Christos, Gerassimidis, Thomas, Kostakis, Alkiviadis, Liovpis, Anthanasios, Manolis, Anastasakis, Matsagas, Miltiadis, Pappas, Stavros, Alsayegh, Faisal, Losonczy, Hajna, Bernath, Bela, Kecskes, Gabor, Lakatos, Jozsef, Ledniczki, Istvan, Nyuzo, Balint, Zeher, Margit, Pinjala, Ramakrishna, Agnihotri, Vinod, Balraj, A., Chakraborty, Amiya, Desai, Sanjay, Elangovan, Antony, Goswami, Partha, Rupert, Emmanuel, Toraskar, Kedar, Venkatesh, Kakollu, Gaine, Sean, Connaughton, John, Costello, Richard, Liston, Richard, Zubieta, Ricardo Martinez, Avila Fematt, Flor Mario, Baeza Esponda, Juan Alejandro, Benitez Maldonado, Daniel R., Escarela Serrano, Maricela, Lavalle Montalvo, Carlos, Lopez Marquez, Santa, Quesada Sanchez, Alejandro, Ramirez Diaz, Santiago, Tovar Serrano, Alejandro, Villa de la Vega, Maria Isabel, Faridi, Salman, Javaid, Mansur, Khan, Farrukh, Malik, Asif Zafar, Sadiq, Muzafaruddin, Yusaf-Shah, Muhammad, Musial, Jacek, Biedziuk, Bartlomiej, Gellert, Ryszard, Klonowski, Wlodzimierz, Kosiniau-Kamysz, Andrzey, Prajs, Zozislav, Constantin, Palivan, Gostian, Ovidiu, Grintescu, Ioana Marina, Mimor, Ovidiu, Natalia, Hagau, Puiac, Claudiu, Valerica, Stan, Sulimov, Vitalyi Andreevich, Belentsov, Sergey, Dubrovnaya, Nina, Eliseeva, Ekaterina, Fridman, Irina, Kazantchian, Perch, Mashtacov, Boris, Redkin, Alexander, Rodoman, Grigory, Zhidkov, Konstantin, Gaspa, L'udovit, Barta, Peter, Benova, Katarina, Duris, Tibor, Fecik, Juraj, Hajas, Jan, Herman, Oto, Lehotsky, Jan, Macek, Vladimir, Pradova, Viera, Arcelus, Juan, Carrascosa, Miguel, Cuenca Luque, Rafael, del Val Gil, Jose, Diaz de Souza, Pedro, Alvaro Enfedaque, Muriel, Garcia Sanchez, Florentino, Guil Garcia, M., Luis Lobo-Beristain, Jose, Lopez, Luciano, Nieto Rodriguez, Jose Antonio, Mateo Paredes, Ramon, Ramos Rodriguez, Jose Luis, Ruiz Cantero, Alberto, Ruiz Lorenzo, Pedro, Clavo Sanchez, Antonio, Soto Cardenas, Maria Jose, Valle Bernad, Reina, Vela Moreno, Jeronimo Ramon, Doerffler, Janine, Beer, Jurg, Brunner, Brigitte, Chopard, Pierre, Ludwig, Christian, Peter, Jurg, Rime, Francis, Salomon, Franco, Ulrich, Munch, Angchaisuksiri, Pantep, Chetanachan, Mariam, Chuamuangphan, Nonlawan, Insiripong, Somchai, Nawarawong, Weerasak, Ben Salah, Afif, Ghedira, Habib, Houman, Mohamed Habib, Mohamed, Mnif, Samir, Kammoun, Zouheir, Jerbi, Ongen, Gul, Cirak, Ali Kadri, Demirtas, Nazmi, Dokucu, Ali, Erden, Faruk, Guven, Hulya, Halezeroglu, Semih, Karaoglan, Halim, Tereci, Hikmet, Cohen, Alexander, Calvey, Thomas, Gallegos, Nick, Gaminara, Elizabeth, James, Anthony, Jeffreys, Mike, Keaney, Niall, Khan, Zafar, Mackie, Peter, Mallick, Abhiram, Marval, Paul, Parapia, L., Picozzi, Natalie, Praveen, Bandipalyam, Satchi, Gnanam, Valerio, David, Tapson, Victor, Antonacci, Anthony, Baker, Gennfer, Beaver, Richard, Becker, William, Beckett, Cynthia, Borchardt, Carla, Briggs, Michael, Bruckman, Joseph, Buck, Lisa, Caushaj, Philip, Chausow, Alan, Chowdary, Madhu, Christopulos, Danielle, Cica, Paula, Cody, Jean, Condit, Bruce, Cronin, Sherill, Diefendorf, Anne, Driggers, Steven, Ellis, Paula, Elvenia, Jaeda, Feinbloom, David, Feldman, Mark, Fischer, Marian, Froehlich, James, Frost, Christopher, Gaffey, Joseph, Galster, Ruth, Geldmeier, Richard, Glielmi, Vincent, Goodwin, James, Gottlieb, Anita, Gray, Bruce, Henry, Edwina, Hernandez, Cecilia, Hill, David, Hutchinson, Melissa, Johnson, Juanita, Johnson, Roberta, Kapre, Sheela, Kowaloff, Harvey, Krodel, John, Lehman, James, Marney, Terri, Marshall, Ingeborg, McDaniels, Mary, Middleton, Robert, Mitchell, Phillip, Nelson, Carrie, Netherland, Susan, Ogden, Maureen, Packard, Keith, Pieske, Marlys, Poole, Lorie, Radford, Martha, Roberts, Cathy, Robinson, Margaret, Rollins, David, Rubinate, Donna, Schmidt, Cheryl, Scott, Julia, Shutt, Sandra, Slone, Betty, Spyropoulos, Alex, Subramanian, Seshan, Sullivan, Jacqueline, Timmerman, Carman, Wheeler, Connie, White, Diane, White, Nancy, Whitehead, Alva, Wright, Joyce, and Young, Dereck

Subjects
cardiovascular diseases, equipment and supplies
Abstract

Objective: To evaluate venous thromboembolism (VTE) risk in patients who underwent a major operation, including the use of, and factors influencing, American College of Chest Physicians-recommended types of VTE prophylaxis.

Published
2010

11. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency

Author

Salomon, Franco, Cuneo, Ross C., Hesp, Richard, and Sonksen, Peter H.

Subjects
Pituitary gland, Somatotropin -- Health aspects, Energy metabolism -- Research
Abstract

Growth hormone (GH) is normally produced by the pituitary gland. GH induces the synthesis of proteins, increases the breakdown of fats for energy and decreases the use of carbohydrates in the body. GH induces skeletal growth in children but not in adults. After surgery to remove pituitary tumors, patients are treated with various hormones that the pituitary gland controls the production of, such as thyroid, adrenal and gonadal hormones. However, the patients still do not generally feel well. Replacement of growth hormone is now possible, as it is available in large quantities because it is produced artificially. In this study, 24 adults with growth hormone deficiency as a consequence of surgery for pituitary tumors were treated for six months with human recombinant growth hormone (rhGH). No increase in overall body weight occurred after treatment, although a change in body composition was noted. The average lean body mass, of which muscle is the major component, increased by approximately 5.5 kilograms or 12 pounds and the fat mass decreased by approximately 5.7 kilograms. GH is known to metabolize fat, and thus increase the metabolic rate of the body. The basal metabolic rate of the patients in the study increased significantly over the six-month treatment period. Cholesterol levels were lower in the group given the hormone but triglycerides were the same in both the treated and untreated groups. Treatment of deficient adults with growth hormone has a positive effect on the composition of their bodies, with an increase in lean muscle mass and decrease in fat and cholesterol.

Published
1989

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