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Ewing’s sarcoma, a rare primary bone malignancy primarily affecting adolescents and young adults, typically manifests in the pelvic bones and femur. Primary Ewing’s sarcoma of the sternum is exceptionally rare, constituting less than 1% of cases. We present a case of a 34-year-old man with a 2-month history of anterior chest wall pain initially attributed to muscular spasm. Subsequently, the patient developed a palpable mass and imaging demonstrated a mid-lower sternal lesion with cortical destruction and soft tissue involvement, confirmed as Ewing’s sarcoma on biopsy. In addition, a suspicious lesion was identified in the left distal tibia, which was histologically confirmed as a metastasis from the primary sternal sarcoma. Neoadjuvant chemotherapy preceded partial sternotomy with rib resection and reconstruction, achieving clear surgical margins. Postoperative evaluation showed shrinkage in the sternal lesion and near-resolution of the tibial metastasis. Subsequent chemotherapy cycles resulted in no evidence of the disease on the follow-up positron emission tomography scan. This case underscores the diagnostic challenges of primary sternal Ewing’s sarcoma and emphasizes the importance of early recognition and comprehensive evaluation in managing such rare presentations.

Butheinah A Al-Sharafi,1 Ahmed A Qais,1 Khalil Salem,2 Muneer O Bashaaib2 1Department of Internal Medicine, School of Medicine and Health Sciences, Sana’a University, Sana’a, Yemen; 2Department of Internal Medicine, University of Science and Technology Hospital, Sana’a, YemenCorrespondence: Butheinah A Al-Sharafi Email balsharafi@hotmail.comObjective: Overweight and obese adults are at high risk for developing prediabetes and diabetes. The aim of this study was to measure the prevalence of prediabetes (pre-DM) and diabetes (DM) among Yemeni adults who were overweight or obese and had first-degree relatives with DM, consanguinity and other risk factors.Patients and Methods: This cross-sectional study included 612 adults, all with a BMI≥ 25 kg/m2. BMI, blood pressure (BP) and waist circumference (WC) were measured in the clinic. Fasting blood glucose (FBG) was collected for all subjects. The patients either had first-degree relatives with diabetes or not, and the subjects answered a questionnaire regarding the consanguinity of their parents, exercise, khat chewing, smoking, and eating vegetables and fruits daily.Results: Of the 612 study participants (32% males and 68% females) aged 20– 70 years old, 429 (70.1%) had a family history (FM) of DM ± consanguinity of parents, and 183 (29.9%) had no FM of diabetes. Multivariate analysis showed significant risk in those with class III obesity for pre-DM (AOR 3.10 95% CI 1.56– 6.18 p value 0.001) and DM (AOR 3.35 95% CI 1.47– 7.65 p value 0.004) and those who had siblings with DM had a risk for pre-DM (AOR 1.72 95% CI 1.09– 2.71 p value 0.02) and DM (AOR 2.24 95% CI 1.25– 4.0 p value 0.007). Khat chewing increased the risk for pre-DM (AOR 1.61 95% CI 1.04– 2.48 p value 0.032) and for DM (AOR 2.09 95% CI 1.14– 3.82 p value 0.017). Having consanguineous parents plus siblings with DM were associated with a higher risk of DM (p value 0.031).Conclusion: There is a high prevalence of pre-DM and undiagnosed DM among overweight and obese Yemeni individuals. Class III obesity, having siblings with DM, chewing khat, and having consanguineous parents plus siblings with DM all increased the risk. This group should be screened at an early age for early detection of pre-DM and DM.Keywords: Yemen, prediabetes, diabetes, prevalence, overweight, obese, consanguinity, khat-chewing

Gas injection is a frequently used method for artificial lift and flow regime rectification in offshore production and transportation flowlines. The flow behaviour in such flowlines is complex and a better understanding of flow characteristics, such as flow patterns, void fraction/hold up distributions and pressure gradient is always required for efficient and optimal design of downstream handling facilities. Injection method and location have been shown to strongly affect downstream fluid behaviour that can have important implications for pumping and downstream facility design, especially if the development length between pipeline and downstream facility is less than L/D = 50 as reported by many investigators. In this article, we provide the results of an experimental investigation into the effects of the gas injection position on the characteristics of the downstream upwards vertical gas flow using a vertical riser with an internal diameter of 52 mm and a length of 10.5 m. A horizontal 40-m-long section connected at the bottom provides options for riser base or horizontal flow line injection of gas. The flowline gas injection is performed 40 m upstream of the riser base. A 16 by 16 capacitance wire mesh sensor and a gamma densitometer were used to measure the gas-liquid phase cross-sectional distribution at the riser top. A detailed analysis of the flow characteristics is carried out based on the measurements. These include flow regimes, cross-sectional liquid holdup distributions and peaking patterns as well as analysis of the time series data. Our findings show that flow behaviours differences due to different gas injection locations were persisting after a development length of 180D in the riser. More specifically, core-peaking liquid holdup occurred at the lower gas injection rates through the flowline, while wall-peaking holdup profiles were established at the same flow conditions for riser base injection. Wall peaking was associated with dispersed bubbly flows and hence non-pulsating as against core-peaking was associated with Taylor bubbles and slug flows. Furthermore, it was found that the riser base injection generally produced lower holdups. It was noted that the circumferential injector used at the riser base promoted high void fraction and hence low liquid holdups. Due to the bubbly flow structure, the slip velocity is smaller than for larger cap bubbles and hence the void fraction is higher. The measurements and observations presented in the paper provides valuable knowledge on riser base/flowline gas introduction that can directly feed into the design of downstream facilities such as storage tanks, slug catchers and separators.

The properties of polyethylene glycol-6000 (PEG)/MgCaCO3, a low-cost shape-selective phase change material (ss-PCM), make it highly suitable for solar thermal applications. Nanosized porous MgO-doped CaCO3 with Mg molar concentrations of 5%, 10%, and 15% were synthesized using a hydrothermal technique. The prepared MgO-CaCO3 matrices were then impregnated with PEG to obtain PEG/MgCaCO3 as an ss-PCM. Samples identified as PEG-5MgCaCO3 (P-5-MCC), PEG-10MgCaCO3 (P-10-MCC), and PEG-15MgCaCO3 (P-15-MCC) were prepared and studied. Interestingly, P-10-MCC has the smallest particle size together with a good porous structure compared to the other two materials. The results of thermogravimetric analyses and differential scanning calorimetry indicate that the small particle size and porous structure facilitate the impregnation of approximately 69% of the PEG into the 10-MCC matrix. The latent heat and energy storage efficiency of PEG in the P-10-MCC sample are 152.5 J/g and 96.48%, respectively, which are significantly higher than those of comparable materials. Furthermore, in addition to the improvement of the thermal conductivity of the P-10-MCC, its supercooling is also reduced to some extent. The combined mesoporous and macro-porous structure of P-10-MCC is critical to retaining a large amount of PEG within the matrix, resulting in a high latent heat in the operating temperature range of 35–57 °C. The P-10MCC sample also demonstrates a high energy storage capacity (98.59%), high thermal energy storage/release rates, and exceptional shape-stabilized PCM properties.

Proper selection and application of interfacial friction factor correlations has a significant impact on prediction of key flow characteristics in gas–liquid two-phase flows. In this study, experimental investigation of gas–liquid flow in a vertical pipeline with internal diameter of 0.060 m is presented. Air and oil (with viscosities ranging from 100–200 mPa s) were used as gas and liquid phases, respectively. Superficial velocities of air ranging from 22.37 to 59.06 m/s and oil ranging from 0.05 to 0.16 m/s were used as a test matrix during the experimental campaign. The influence of estimates obtained from nine interfacial friction factor models on the accuracy of predicting pressure gradient, film thickness and gas void fraction was investigated by utilising a two-fluid model. Results obtained indicate that at liquid viscosity of 100 mPa s, the interfacial friction factor correlation proposed by Belt et al. (2009) performed best for pressure gradient prediction while the Moeck (1970) correlation provided the best prediction of pressure gradient at the liquid viscosity of 200 mPa s. In general, these results indicate that the two-fluid model can accurately predict the flow characteristics for liquid viscosities used in this study when appropriate interfacial friction factor correlations are implemented.

An investigation has been carried out to study the effect of the wind parameters on the response of multistory buildings subjected to wind induced forces. This study is concerned with the wind response of the buildings located at six building sites in Sohar, Thumrait and Saiq regions of Oman. A typical plan of multistory-framed building has been chosen for the present investigation. The Wind and the other related data appropriate to these regions have been used in the analysis. It turns out from the present study that the response of the building located at a Site in a country terrain of a region has higher values than the response obtained for the same building if constructed in a town terrain of the same region With other parameter combinations remaining invariant. It is recommended that a database for the wind parameters, based on the available wind and other related data for different regions of Oman, should be developed for the design of buildings subjected to wind induced farces.

Background Premature newborns are susceptible to retinopathy of prematurity (ROP), a vasoproliferative disease of the developing retinal vessels, which is a major cause of potentially avoidable blindness. Due to geographical variations in newborn care, geographic variations in the epidemiology of ROP have been observed internationally during the last several decades. There was a correlation between the severity of the condition and the number of prenatal, postnatal, and other risk factors. This study aimed to examine the incidence and risk factors associated with retinopathy of prematurity in preterm infants. Methods A retrospective review of preterm newborns evaluated for retinopathy of prematurity between January 2016 and December 2022 was carried out at King Fahd Hospital of the University (KFHU), Khobar, Saudi Arabia. Infants who fulfilled the screening criteria (GA < 34 or Birth Weight (WT) ≤ 1500 g) underwent the screening test, and the International Classification of Retinopathy of Prematurity was used to classify retinopathy of prematurity. Risk factors and demographic information regarding ROP were assessed. Statistical analysis was performed using SPSS (version 20) with a 95% confidence interval (CI). Statistical significance was set at p < 0.05. Results Among the 200 preterm neonates that were evaluated and admitted to neonatal critical care units, 37% exhibited premature retinopathy, with 46.7% of those cases being in stage 1. The development of ROP was linked to gestational age, length of mechanical ventilation, septicemia, intraventricular hemorrhage, bronchopulmonary dysplasia, respiratory distress syndrome, and septicemia, according to univariate and multivariate logistic regression analyses. Conclusion The incidence of total retinopathy in premature infants in this population was 37%. Evaluating these risk factors during the screening of high-risk premature infants will help determine the appropriate timing of examinations and treatment.

Ewing's sarcoma, a rare primary bone malignancy primarily affecting adolescents and young adults, typically manifests in the pelvic bones and femur. Primary Ewing's sarcoma of the sternum is exceptionally rare, constituting less than 1% of cases. We present a case of a 34-year-old man with a 2-month history of anterior chest wall pain initially attributed to muscular spasm. Subsequently, the patient developed a palpable mass and imaging demonstrated a mid-lower sternal lesion with cortical destruction and soft tissue involvement, confirmed as Ewing's sarcoma on biopsy. In addition, a suspicious lesion was identified in the left distal tibia, which was histologically confirmed as a metastasis from the primary sternal sarcoma. Neoadjuvant chemotherapy preceded partial sternotomy with rib resection and reconstruction, achieving clear surgical margins. Postoperative evaluation showed shrinkage in the sternal lesion and near-resolution of the tibial metastasis. Subsequent chemotherapy cycles resulted in no evidence of the disease on the follow-up positron emission tomography scan. This case underscores the diagnostic challenges of primary sternal Ewing's sarcoma and emphasizes the importance of early recognition and comprehensive evaluation in managing such rare presentations. [ABSTRACT FROM AUTHOR]

This study presents the synthesis of a novel ovonic nanomaterial by the chemical route approach, involving the combination of three distinct materials: polyvinyl alcohol (PVA), iron oxide (Fe2O3), and selenium (Se) nanoparticles. The produced material underwent evaluation using various analytical techniques, including Xray diffraction (XRD), energy-dispersive Xray spectroscopy (EDS), scaning electron microscope (SEM), and UV-Visible spectrophotometer. The focus of the work revolved around a unique hybrid structure consisting of selenium nanoparticles that were embedded within a polyvinyl alcohol and iron(III) oxide. The examination of micro structure information yielded findings that support the notion that Se nanoparticles have an impact on the structural properties of PVA/Fe2O3. (XRD) and (EDS) examines provided confirmation of the formation of a novel composite structure. The produced composites had notable absorption peaks at a wavelength of 530 nm for PVA-Fe2O3-CdZnS. These composites exhibited a progressive transition towards absorption in higher wavelength areas. The composite material that has been suggested for potential utilization in forthcoming energy storage applications. [ABSTRACT FROM AUTHOR]

Societal Impact Statement Conserving frankincense trees (Boswellia) is crucial for both ecological and socio‐economic reasons. Surveying these trees in the field and using remote sensing unmanned aerial vehicles in the Socotra Archipelago, we found that Socotran frankincense trees are threatened by forest fragmentation, overgrazing, and increasingly frequent extreme climate events. A better understanding of the distribution and the threats of these important insular species will improve the conservation policy of the local authorities and benefit local communities in the Socotra Archipelago. At the same time, this work serves as a good practice example to guide conservation efforts for other culturally important threatened tree species around the world, therefore helping to sustain local livelihoods, fostering ecological resilience, and supporting socio‐economic stability. Summary Globally, frankincense trees (Burseraceae: Boswellia) are increasingly under threat because of habitat deterioration, climate impacts, and the olibanum trade. Despite harboring nearly half of the species in the genus, up‐to‐date insights are lacking for the insular endemic frankincense trees of the Socotra Archipelago UNESCO (United Nations Educational, Scientific and Cultural Organization) World Heritage Site (Yemen). We combined georeferencing of individual trees in the field with remote sensing applying unmanned aerial vehicles (UAVs) to evaluate Boswellia distribution and (sub)population sizes in the entire Socotra Archipelago. We counted 17,253 trees across all 11 taxa and we surveyed almost 55% directly in the field, collecting individual information on threats and health indicators. We estimate that the current total population sizes of the relatively common Socotran Boswellia taxa (Boswellia elongata, Boswellia popoviana, and Boswellia ameero) consist of a few thousand mature individuals with fragmented distribution of which a large proportion occurs in highly disjunct relictual stands, while the more range‐restricted species survive only through a few hundred (Boswellia nana and Boswellia samhaensis) to fewer than a hundred trees (Boswellia scopulorum). Our field data show that the Socotran frankincense trees are threatened by fragmentation and overgrazing resulting in a lack of natural regeneration, in combination with effects of extreme climate events (e.g., higher frequency and intensity of cyclones and prolonged drought) and potential future infrastructure developments; the species are less impacted by resin collection. We provide recommendations to strategize urgent protection of the declining Socotran frankincense trees, and we update their conservation status, resulting in an endangered status for seven and a critically endangered status for four taxa.