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The present study introduced modifications to the standard Adomian decomposition method (ADM) by combining the Taylor series with orthogonal polynomials, such as Legendre polynomials and the first and second kinds of Chebyshev polynomials. These improvements can be applied to solve fractional differential equations with initial-value problems in the Caputo sense. The approaches are based on the use of orthogonal polynomials, which are essential components in approximation theories. The study carefully analyzed their respective absolute error differences, highlighting the computational benefits of the proposed modifications, which offer improved accuracy and require fewer computational steps. The effectiveness and accuracy of the approach were validated through numerical examples, confirming its efficiency and reliability.

BackgroundArtificial intelligence is experiencing rapid growth, with continual innovation and advancements in the health care field. ObjectiveThis study aims to evaluate the application of artificial intelligence technologies across various domains of respiratory care. MethodsWe conducted a narrative review to examine the latest advancements in the use of artificial intelligence in the field of respiratory care. The search was independently conducted by respiratory care experts, each focusing on their respective scope of practice and area of interest. ResultsThis review illuminates the diverse applications of artificial intelligence, highlighting its use in areas associated with respiratory care. Artificial intelligence is harnessed across various areas in this field, including pulmonary diagnostics, respiratory care research, critical care or mechanical ventilation, pulmonary rehabilitation, telehealth, public health or health promotion, sleep clinics, home care, smoking or vaping behavior, and neonates and pediatrics. With its multifaceted utility, artificial intelligence can enhance the field of respiratory care, potentially leading to superior health outcomes for individuals under this extensive umbrella. ConclusionsAs artificial intelligence advances, elevating academic standards in the respiratory care profession becomes imperative, allowing practitioners to contribute to research and understand artificial intelligence’s impact on respiratory care. The permanent integration of artificial intelligence into respiratory care creates the need for respiratory therapists to positively influence its progression. By participating in artificial intelligence development, respiratory therapists can augment their clinical capabilities, knowledge, and patient outcomes.

Cold stress has an immediate impact on plant structure and function. A large number of free radicals cause oxidative stress in plants. Cold stress causes altered membrane permeability, lipid peroxidation, and DNA damage. It denatures enzymes and disrupts plant metabolism. Different methods are being investigated for acclimatizing plants subjected to cold stress. Nanobiotechnology and bacterial strains are growing agricultural strategies. Nanoparticles’ (NPs) unique qualities (small size, high mobility, biocompatibility, low cost, and increased reactivity) make them ideal candidates in agriculture. NP and bacterial applications maintain plastid structure and function, enhance antioxidant activities, secondary metabolites, and hormone expression, and reduce electrolyte leakage. They increase the number and content of proteins involved in oxidation–reduction reactions, hormone pathways, stress signaling, and reactive oxygen species detoxification under cold stress conditions. Chitosan, zinc oxide, and titanium dioxide NPs can help plants with cold stress. Meanwhile, bacterial strains in the genus Bacillus and Pseudomonas have been tested for cold tolerance. These strategies also upregulate antifreeze proteins, which are essential for the storage of plant products. Nano-bio-fertilizers should be prepared for the sustainable development of plants under low temperatures.

According to their respective positions, participants at the local, regional, and global actors within the poultry farming sector play strategic roles according to their respective positions. While these roles may integrate and overlap, they can also generate conflicts of interest at both the actor and institutional levels. This study analyses the actors and power relations in laying hen farming in Blitar Regency, East Java, Indonesia. The data were collected using structured interview techniques (interview guides and Matrix of Alliances and Conflicts: Tactics, Objectives and Recommendations questionnaires), observation, documentation, and focus group discussions. The research informants were chosen deliberately based on various sources including farmers, farmer groups, cooperative, central and local government, companies, and traders. This was in addition to informants obtained using the snowball sampling technique such as middlemen, poultry shops (PSs) and other additional breeders. Data validity was determined using source triangulation and method triangulation. The results revealed that the individuals and entities engaged in layer hen farming encompass a diverse range of actors. These include farmers of various scales (small, medium, and large), institutions such as farmer groups and cooperatives, governmental bodies at both central and regional levels, industry representatives such as companies, PSs, distributors involved in producing and marketing day-old chick (DOC), feed, medicines, and vaccines, as well as market participants including local traders and traders operating across different regions. Small-scale and medium-scale farmers have the strongest relationships due to their high dependence on inputs such as DOC, feed, vaccines, and access to markets. The presence of various actors and power relations in laying hen business institutions creates both collaboration and competition in the supply of DOCs, animal feed, medicine, and even in the marketing of eggs from a food security and sustainability perspective.

BackgroundDrug-resistant epilepsy (DRE) impacts a significant portion, one-third, of individuals diagnosed with epilepsy. In such cases, exploring non-pharmacological interventions are crucial, with the ketogenic diet (KD) standing out as a valuable option. KD, a high-fat and low-carb dietary approach with roots dating back to the 1920s for managing DRE, triggers the formation of ketone bodies and modifies biochemistry to aid in seizure control. Recent studies have increasingly supported the efficacy of KD in addressing DRE, showcasing positive outcomes. Furthermore, while more research is needed, limited data suggests that KD May also be beneficial for specific genetic epilepsy syndromes (GESs).ObjectiveThis study aimed to assess the short-term efficacy of KD among pediatric patients diagnosed with GESs.Materials and methodsThis is a multi-center retrospective analysis of pediatric patients with GESs diagnosed using next-generation sequencing. The enrolled patients followed the keto-clinic protocol, and the KD efficacy was evaluated at 3, 6, and 12-month intervals based on seizure control and compliance. The collection instrument included demographic, baseline, and prognostic data. The collected data was coded and analyzed promptly.ResultsWe enrolled a cohort of 77 patients with a mean current age of 7.94 ± 3.83 years. The mean age of seizure onset was 15.5 months. Notably, patients experienced seizures at a younger age tended to have less positive response to diet. Overall, 55 patients responded favorably to the diet (71.4%) while 22 patients (28.6%) showed no improvement. Patients with genetic etiology showed a significantly more favorable responses to the dietary intervention. Patients with Lennox–Gastaut syndrome showed the most significant improvement (14/15) followed by patients with Dravet syndrome (6/8), and West syndrome (3/4). The number of used anti-seizure medications also played a significant role in determining their response to the diet. While some patients experienced mild adverse events, the most common being constipation, these occurrences were not serious enough to necessitate discontinuation of the diet.ConclusionThe study revealed a high improvement rate in seizure control, especially among younger patients and those with later seizure onset. The success of dietary treatment hinges greatly on early intervention and the patient’s age. Certain genetic mutations responded favorably to the KD, while efficacy varied among various genetic profiles.

Careful study of applied sciences and their development requires us to expand the scope of analytical studies. We aim during introducing the current manuscript to rediscover and present Grüss inequality in a new framework. In order to do that, we use the recently generalized proportional fractional integral operator for a certain function with respect to another continuous and strictly increasing function. Furthermore, we prove some new related inequalities using the current fractional integral operator. Some special cases of the presented results will be discussed.

This research paper presented a novel investigation into an implicit coupled system of fractional variable order, which has not been previously studied in the existing literature. The study focused on establishing and developing sufficient conditions for the existence and uniqueness of solutions, as well as the Ulam-Hyers stability, for the proposed coupled system without using semigroup property. By extending the existing conclusions examined for the Atangana-Baleanu-Caputo (ABC) operator, we contributed to advancing the understanding of variable-order fractional differential equations. The paper provided a solid theoretical foundation for further analysis, numerical simulations, and practical applications. The obtained results have implications for designing and controlling systems modeled using fractional variable order equations and serve as a basis for addressing a wide range of dynamical problems. The transformation techniques, qualitative analysis, and illustrative examples presented in this work highlight its unique contributions and potential to serve as a foundation for future research.

The primary focus of this paper is to thoroughly examine and analyze a class of a fractional quadratic integral equation via generalized fractional integral. To achieve this, we introduce an operator that possesses fixed points corresponding to the solutions of the fractional quadratic integral equation, effectively transforming the given equation into an equivalent fixed-point problem. By applying the Banach fixed-point theorems, we prove the uniqueness of solutions to fractional quadratic integral equation. Additionally, The Adomian decomposition method is used, to solve the resulting fractional quadratic integral equation. This technique rapidly provides convergent successive approximations of the exact solution to the given fractional quadratic integral equation, therefore, we investigate the convergence of approximate solutions, using the Adomian decomposition method. Finally, we provide some examples, to demonstrate our results. Our findings contribute to the current understanding of fractional quadratic integral equation and their solutions and have the potential to inform future research in this area.

ObjectiveTo explore the relationship between Oxygenation Index (OI) and Oxygen Saturation Index (OSI) among infants with Congenital Diaphragmatic Hernia (CDH), both within the first 24 h after birth and in extended observations in those who survived until their surgical intervention.MethodsSeven- years retrospective review of CDH cases at a single Level III neonatal intensive care unit. The correlations of various combinations of OI-OSI pairs were assessed using the Spearman's rho Correlation Coefficient. Additionally, during the initial 24 h, the correlations between admission (first), best (lowest), highest, and mean OI and OSI values were determined. The predictive ability of the first 24 h oxygen and oxygen saturation indices for mortality and other adverse outcomes were assessed using the Area Under the Curve (AUC) analysis.ResultsThirty-seven infants with CDH were included in the analysis. A strong correlation was observed between all pairs of OI/OSI (2,289) (Spearman's rho = 0.843), matched pairs of Postductal OI/OSI (1,232 pairs) (Spearman's rho = 0.835) and the unmatched pairs of Postductal OI and Preductal OSI (1,057 pairs) (Spearman's rho = 0.852). Using the regression equations for all pairs, matched and unmatched OI/OSI pairs, we deduced that for clinically pertinent OI thresholds of 10, 15, 20 and 40, the corresponding OSI values were 5, 8, 11, and 23, respectively. Furthermore, in the first 24 h, strong correlations were evident between OI/OSI: at admission (Spearman's rho = 0.783), best OI/OSI (Spearman's rho = 0.848), and highest OI/OSI (Spearman's rho = 0.921). The most robust correlation was observed between the mean OI/OSI with a Spearman's rho of 0.928. First (AUC = 0.849), best (AUC = 0.927), highest (AUC = 0.942) and mean day 1 OI (AUC = 0.946) were all predictive of mortality. Similarly, first (AUC = 1.00), best (AUC = 0.989), highest (AUC = 1.00) and the mean OSI in day 1 (AUC = 0.978) were all predictive of mortality. All of the OIs and OSIs in day 1 except for the admission OSI (AUC = 0.683) were predictive of pulmonary hypertension. Additionally, all of OI and OSI indices in the first 24-hour except for the best day 1 OI (AUC = 0.674) were predictive of the need for rescue HFOV.ConclusionThere were a strong correlation between the OI and OSI in infants with CDH. Oxygenation indices and OSI in the first 24 h were predictive of mortality and other adverse outcomes in infants with CDH.

Objective. To examine the postnatal predictors of survival and adverse outcome among Congenital Diaphragmatic Hernia (CDH) infants. Method. Six-year retrospective review of CDH infants born at tertiary neonatal unit. Results. Forty infants with CDH were included; 27 (67.5%) survived to discharge. Non-survivors had a higher best, mean, and highest oxygenation index (OI) ( P

Objective . To describe heated humidified high-flow nasal cannulas (HHHFNC) utilization in level III neonatal intensive care units (NICUs) in Saudi Arabia. Methods . A prospective cross-sectional study using an electronic web-based questionnaire. The survey targeted level III NICUs hospitals using HHHFNCs, covering HHHFNC availability, protocols, patient characteristics, and indications. It also collected opinions on the benefits of HHHFNCs compared to nasal continuous positive airway pressure (nCPAP). Results . Out of 47 government-level III neonatal intensive care units, 35 (74%) responded to the survey. Among the included units, 46% had guidelines for HHHFNC use. Additionally, 51% reported using HHHFNC in infants of all gestational ages. The primary indication for HHHFNC use was weaning off nCPAP (34%), with 60% of the respondents noting its advantages for kangaroo care and breastfeeding. Conclusion . HHHFNC are increasingly prevalent in NICUs in Saudi Arabia. However, there remain no clear policies or guidelines regarding their use in preterm infants.

Introduction: Imposter syndrome is common among health disciplinary students, leading to serious consequences. However, the impact of imposter syndrome on self-esteem and quitting intention among respiratory therapy students has not been well researched. Objective: To report on the prevalence of imposter syndrome and assess its impacts on self-esteem and quitting intention among respiratory therapy students in Saudi Arabia. Methods: A nonprobability cross-sectional questionnaire using the Clance Impostor Phenomenon Scale and the Rosenberg Self-Esteem Scale was self-administered and distributed among respiratory therapy students between October 2022 and April 2023. Data analysis was performed using Descriptive and inferential statistics. Results: Of the 1500 respiratory therapy students invited to participate in the study, 901 surveys were completed; and thus, included in the final analysis. Of whom, 92% were presented with imposter syndrome: 44% with moderate, 35% with frequent, and 13% with intense feelings. In addition, 60% of respiratory therapy students and interns experienced low self-esteem, while only 0.5% indicated high self-esteem. More than 50% of the study participants thought about quitting the respiratory therapy program, and 30% have been diagnosed with psychological disorders. Furthermore, there was a significant association between imposter syndrome and low self-esteem, p 0.005). Conclusion: Imposter syndrome and low self-esteem are prevalent among respiratory therapy students, both of which are associated with considering leaving the respiratory therapy program. Effective interventions should be implemented to ameliorate the symptoms imposter syndrome and low self-esteem; thus, improving the academic experience of respiratory therapy students.

Egyptian Jallab (EJ) is a conical candy (light to dark brown), manufactured from a part of sugar cane juice, that is used in the black honey industry. EJ is considered an unrefined sugar or a non-centrifugal form of sugar. The traditional use of Jallab is as candy, but it can also be used for making ice cream, cupcakes, biscuits, and toffee, as well as being used in other food applications. In this study, EJ was used as a sugar substitute in ice cream at 0, 25, 50, 75, and 100%. Total solids, titratable acidity, pH, protein, ash, fat, specific gravity, weight per gallon, viscosity, color attributes, total antioxidant activity, total phenolic content, and total flavonoid contents, as well as microbiological analyses, were tested. The total solids, protein, and ash in the Egyptian Jallab ice cream (EJIC) increased from 39.30, 4.85, and 0.87 to 41.19, 6.36, and 1.42, respectively. The gradual sugar substitution led to a significant increase in specific gravity and weight per gallon in pounds. The lightness (L*) of the ice cream decreased significantly due to the substitution of EJ for sugar. Moreover, there was a significant increase in a* (from 0.147 in control samples to 5.52 in treatment 4, which had 100% EJ). The changes in the b* values of Jallab ice cream samples were significantly increased due to the substitution of EJ for sugar. The control samples had a low value of antioxidant activity (21.53%) when compared with the treatment, which has EJ (88.82, 89.96, 91.98, and 92.14%) for EJIC1, EJIC2, EJIC3, and EJIC4, respectively. The total phenolic contents are 2.07, 3.03, 4.14, and 4.68 fold higher in the treatments with EJ substituted for sugar than in the control samples. Total flavonoid contents increased from 5.73 mg QE g−1 in control samples (TC) to 14.68, 21.54, 30.48, and 34.15 mg QE g−1 in EJIC1, EJIC2, EJIC3, and EJIC4 mg QE g−1 in ice cream samples, respectively.

Introduction Electronic cigarette (e-cigarette) use is gaining popularity among adults. Monitoring e-cigarette-induced respiratory symptoms is crucial for both clinical and regulatory purposes. We systematically reviewed the current literature to understand the prevalence of respiratory symptoms among exclusive e-cigarette users, dual users, and former smokers. Methods Databases searched included PubMed, CINAHL, Cochrane Library, Embase, and Scopus. We included all English-language, empirical quantitative articles that explored the prevalence of e-cigarette-related respiratory symptoms. Random-effects models were utilized in conducting the meta-analyses. The quality of identified studies was evaluated using the NIH Study Quality Assessment Tools. This study is registered with PROSPERO(#CRD42020165973). Results The literature search identified 1240 references. After removing duplicates and screening for eligibility, 168 studies were included in the final review. The majority of included studies reported a wide range of adverse respiratory symptoms. The respiratory symptoms were prevalent among the exclusive e-cigarette users, dual users, and those who switched from combustible cigarettes to e-cigarettes. Further, out of the RCT studies, 5 were rated as good quality, while 3 were rated as fair. Among the observational studies, 24 were rated as good quality, and 9 were rated as fair. The two experimental studies were both rated as fair quality. Conclusions Continued monitoring of respiratory symptoms among e-cigarette users is warranted. Due to the heterogeneity and inconsistencies among studies, which limit result interpretation and highlight the need for studies assessing causal inference, further research using robust study designs is essential. This will provide clinicians with comprehensive knowledge about the potential respiratory risks of e-cigarette use.

This study aims to examine the dynamics of subsidized fertilizer management in rice production areas in Sidrap and Wajo districts, South Sulawesi province. Using a case study approach with qualitative analysis, the study combined primary data from in-depth interviews and secondary data derived from various studies and reports from government organizations. The results show that there is a considerable gap between the government’s fertilizer budget and farmers’ actual needs, leading to coverage of only 37%, thus forcing farmers to purchase more expensive non-subsidized fertilizers. The inefficient distribution system results in delays and scarcity. As a result, there will be market and price dualism between subsidized and non-subsidized markets, as well as subsidized and non-subsidized prices. Enforcement of pricing regulations faces hurdles due to the black market. In addition, farmers use the “foster father” system to obtain credit. To improve fertilizer management, the study recommends a multifaceted approach: increased budget allocation, efficient distribution, strong enforcement of pricing regulations, and innovative financing solutions such as the Tani Card. These strategies, along with improved inter-agency coordination, aim to address challenges and increase the effectiveness of subsidized fertilizer policies.

Background and Objectives: Asthma is associated with several comorbidities, one of which is obesity. The worldwide increase in obesity has been accompanied by a parallel rise in asthma prevalence, with obesity recognized as a significant risk factor for both the development and severity of asthma. Obesity is often linked to various comorbidities, which can complicate asthma management and lead to poorer clinical outcomes. This study aims to investigate the prevalence of obesity and its comorbidities in adults with asthma in a single center in Saudi Arabia, providing an overview of the associated health implications. Materials and Methods: This single-center, retrospective study aimed to assess the prevalence of obesity and other comorbidities in asthma patients. Data were collected from King Khalid University Hospital in Saudi Arabia between July 2023 and December 2023. Results: This study revealed that 72.1% of asthma patients were either obese or overweight. Female patients had significantly higher BMI values compared to males. Our study revealed that 38.21% of female asthma patients (mean age = 57 ± 13.85 years) had comorbidities compared to 24.14% of male asthma patients (mean age = 59 ± 14.02 years). Furthermore, the proportion of obese asthmatic patients with comorbidities was significantly greater than those without comorbidities. Conclusions: This study investigates obesity prevalence and associated comorbidities in adult asthmatics in a single center in Saudi Arabia. The findings reveal a 72.1% rate of obesity and overweight among asthmatic patients, with higher BMI and comorbidity prevalence in females. These results underscore the need for targeted interventions addressing obesity and comorbidities, especially in female asthmatics.