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217 results on '"Saldiva, Paulo H.N."'

5. Air Pollution Aggravates Renal Ischemia-Reperfusion-Induced Acute Kidney Injury

Author

Sanches, Talita Rojas, primary, Parra, Antonio Carlos, additional, Sun, Peiqi, additional, Graner, Mariana, additional, Itto, Lucas Yuji Umesaki, additional, Butter, Loes, additional, Claessen, Nike, additional, Roelofs, Joris J.T.H., additional, Florquin, Sandrine, additional, Veras, Mariana Matera, additional, Andrade, Maria de Fatima, additional, Saldiva, Paulo H.N., additional, Kers, Jesper, additional, Andrade, Lucia, additional, and Tammaro, Alessandra, additional

Published
2023
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8. Enriched inorganic compounds in diesel exhaust particles induce mitogen-activated protein kinase activation, cytoskeleton instability, and cytotoxicity in human bronchial epithelial cells

Author

Seriani, Robson, Junqueira, Mara S., Carvalho-Sousa, Claudia E., Arruda, Alessandra C.T., Martinez, Diana, Alencar, Adriano M., Garippo, Ana L., Brito, Jôse Mara, Martins, Milton A., Saldiva, Paulo H.N., Negri, Elnara M., Mauad, Thais, and Macchione, Mariangela

Published
2015
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10. Association between Heat Exposure and Hospitalization for Diabetes in Brazil during 2000-2015: A Nationwide Case-Crossover Study

Author

Xu, Rongbin, Zhao, Qi, Coelho, Micheline S.Z.S., Saldiva, Paulo H.N., Zoungas, Sophia, Huxley, Rachel R., Abramson, Michael J., Guo, Yuming, and Li, Shanshan

Subjects
Weather, Type 2 diabetes, Global temperature changes, Morbidity, Time, Elderly, Climate change, Cities and towns, Diseases, Environmental issues, Health, World Health Organization
Abstract

Background: Exposure to excessive heat, which will continue to increase with climate change, is associated with increased morbidity due to a range of noncommunicable diseases (NCDs). Whether this is true for diabetes is unknown. Objectives: We aimed to quantify the relationship between heat exposure and risk of hospitalization due to diabetes in Brazil. Methods: Data on hospitalizations and weather conditions were collected from 1,814 cities during the hot seasons from 2000 to 2015. A time-stratified case-crossover design was used to quantify the association between hospitalization for diabetes and heat exposure. Region-specific odds ratios (ORs) were used to calculate the attributable fractions (AFs). Results: A total of 553,351 hospitalizations associated with diabetes were recorded during 2000-2015. Every 5[degrees]C increase in daily mean temperature was associated with 6% [OR=1.06; 95% confidence interval (CI): 1.04, 1.07] increase in hospitalization due to diabetes with lag 0-3 d. The association was greatest (OR = 1.18; 95% CI: 1.13, 1.23) in those [greater than or equal to]80 y of age, but did not vary by sex, and was generally consistent by region and type of diabetes. Assuming a causal association, we estimated that 7.3% (95% CI: 3.5, 10.9) of all hospitalizations due to diabetes in the hot season could be attributed to heat exposure during the study period. Discussion: Short-term heat exposure may increase the burden of diabetes-related hospitalization, especially among the very elderly. As global temperatures continue to rise, this burden is likely to increase. https://doi.org/10.1289/EHP5688, Introduction Diabetes mellitus is an important public health concern affecting an estimated 422 million (including both diagnosed and undiagnosed) people worldwide (Zhou et al. 2016). It is a heterogeneous condition [...]

Published
2019
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19. Contributors

Author

Abrahamsohn, Paulo A., primary, Adamson, S. Lee, additional, Akgul, Yucel, additional, Alahari, Sruthi, additional, Amato, Paula, additional, Aractingi, Selim, additional, Arck, Petra Clara, additional, Avni, Reut, additional, Bainbridge, Shannon A., additional, Bandeira, Carla L., additional, Bany, Brent M., additional, Bertolin, Kalyne, additional, Bevilacqua, Estela, additional, Bianco, Juares R., additional, Bidarimath, Mallikarjun, additional, Bizinotto, Marcia C., additional, Blaisdell, Adam, additional, Bolon, Brad, additional, Bonnin, Alexandre, additional, Burke, Suzanne D., additional, Caniggia, Isabella, additional, Carniato, Amanda, additional, Chen, Zhilin, additional, Consonni, Sílvio Roberto, additional, Constância, Miguel, additional, Cooper, Wendy N., additional, Costa, Natália S.X., additional, Cox, Brian J., additional, Croy, B. Anne, additional, Da Lozzo Garbelini, Maria Cecília, additional, Dalmorin, Aline F., additional, Dean, Wendy, additional, Degaki, Karina Y., additional, DeMayo, Francesco J., additional, DeMayo, Janet L., additional, Dilworth, Mark, additional, Edwards, Andrew K., additional, Erlebacher, Adrian, additional, Fan, Xiujun, additional, Favaro, Rodolfo, additional, Felker, Allison M., additional, Gerber, Scott A., additional, Gertsenstein, Marina, additional, Gheorghe, Ciprian P., additional, Glazier, Jocelyn D., additional, Goeden, Nick, additional, Gonçalves, Claudia Regina, additional, Goyal, Ravi, additional, Hayakawa, Koji, additional, Hemberger, Myriam, additional, Hirosawa, Mitsuko, additional, Hofmann, Alexander P., additional, Hoshida, Mara S., additional, Isaac, Sarah M., additional, Ito, Shuhei, additional, Janzen-Pang, Judith, additional, Joazeiro, Paulo Pinto, additional, Khosrotehrani, Kiarash, additional, Kommagani, Ramakrishna, additional, Kusinski, Laura C., additional, Langford, Michael B., additional, Li, Han, additional, Lima, Patricia D.A., additional, Lippe, Eliana M.O., additional, Longo, Lawrence D., additional, Lorenzon, Aline R., additional, Lydon, John P., additional, Lye, Stephen J., additional, Mahendroo, Mala, additional, Mayhew, Terry, additional, McDonald, Angela, additional, White McVey, Alice, additional, Mu, Junwu, additional, Remus, Chressen Catharina, additional, Murphy, Bruce D., additional, Murrant, Coral L., additional, Nagata, Tetsuji, additional, Nagy, Andras, additional, Nassar, Dany, additional, Nayak, Nihar R., additional, Neeman, Michal, additional, Olivieri, David N., additional, Paffaro, Valdemar A., additional, Pang, Stephen C., additional, Peng, Annie R., additional, Qu, Dawei, additional, Rahman, Anum, additional, Rätsep, Matthew T., additional, Raz, Tal, additional, Rennie, Monique Y., additional, Rosa, Renata Giardini, additional, Rugonyi, Sandra, additional, Saldiva, Paulo H.N., additional, Sandovici, Ionel, additional, Shiota, Kunio, additional, Shynlova, Oksana, additional, Sibley, Colin P., additional, Simmons, David G., additional, Sled, John G., additional, Sung, Hoon-Ki, additional, Szwarc, Maria M., additional, Tadokoro, Carlos E., additional, Tanaka, Satoshi, additional, Tayade, Chandrakant, additional, Szymanski Toledo, Olga Maria, additional, Tse, M. Yat, additional, Tse, Denise, additional, Matera Veras, Mariana, additional, Wetendorf, Margeaux, additional, Whiteley, Kathie J., additional, Yagi, Shintaro, additional, Yamada, Aureo T., additional, Zenclussen, Ana C., additional, Zhou, Yu-Qing, additional, and Telma Zorn, M., additional

Published
2014
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25. Radiological patterns of incidental epididymitis in mild‐to‐moderate COVID‐19 patients revealed by colour Doppler ultrasound

Author

Carneiro, Felipe, primary, Teixeira, Thiago A., additional, Bernardes, Felipe S., additional, Pereira, Marcelo S., additional, Milani, Giovanna, additional, Duarte‐Neto, Amaro N., additional, Kallas, Esper G., additional, Saldiva, Paulo H.N., additional, Chammas, Maria C., additional, and Hallak, Jorge, additional

Published
2021
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26. The impact of sugar cane-burning emissions on the respiratory system of children and the elderly

Author

Cancado, Jose E.D., Saldiva, Paulo H.N., Pereira, Luiz A.A., Lara, Luciene B.L.S., Artaxo, Paulo, Martinelli, Luiz A., Arbex, Marcos A., Zanobetti, Antonella, and Braga, Alfesio L.F.

Subjects
Lung diseases -- Analysis, Air pollution -- Analysis, Aged -- Analysis, Children -- Analysis
Abstract

We analyzed the influence of emissions from burning sugar cane on the respiratory system during almost 1 year in the city of Piracicaba in southeast Brazil. From April 1997 through [...]

Published
2006

27. Concentrated ambient air particles induce vasoconstriction of small pulmonary arteries in rats

Author

Batalha, Joao R.F., Saldiva, Paulo H.N., Clarke, Robert W., Coull, Brent A., Stearns, Rebecca C., Lawrence, Joy, Murthy, G.G. Krishna, Koutrakis, Petros, and Godleski, John J.

Abstract

The objective of this study was to determine whether short-term exposures to concentrated ambient particles (CAPs) alter the morphology of small pulmonary arteries in normal rats and rats with chronic [...]

Published
2002

30. Immune‐pineal axis protects rat lungs exposed to polluted air

Author

Carvalho‐Sousa, Claudia Emanuele, primary, Pereira, Eliana P., additional, Kinker, Gabriela S., additional, Veras, Mariana, additional, Ferreira, Zulma S., additional, Barbosa‐Nunes, Fernanda P., additional, Martins, Joilson O., additional, Saldiva, Paulo H.N., additional, Reiter, Russel J., additional, Fernandes, Pedro A., additional, da Silveira Cruz‐Machado, Sanseray, additional, and Markus, Regina P., additional

Published
2020
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33. Acute effects of inhalable particles on the frog palate mucociliary epithelium

Author

Macchione, Mariangela, Oliveira, Alexandre P., Gallafrio, Christina T., Muchao, Fabio P., Obara, Marcos T., Guimaraes, Eliane T., Artxa, Paulo, King, Malcolm, Lorenzi-Filho, Geraldo, Junqueira, Virginia C.B., and Saldiva, Paulo H.N.

Subjects
Air pollution -- Health aspects, Mucociliary system -- Health aspects, Respiratory tract diseases -- Research
Abstract

The effect of toxic air particles on the respiratory tract of frogs is examined, focusing on the effect on the ciliated epithelium. Results indicated the deleterious effect of the air particles in the experiment but it is difficult to extrapolate the results to health effects on human beings in urban areas.

Published
1999

37. Neonatal capsaicin treatment decreases airway and pulmonary tissue responsiveness to methacholine

Author

Sakae, Regina S., Leme, Adriana S., Dolhnikoff, Marisa, Pereira, Patricia M., Patrocinio, Maria Do, Warth, T.N., Zin, Walter A., Saldiva, Paulo H.N., and Martins, Milton A.

Subjects
Lungs -- Research, Tachykinins -- Analysis, Rats -- Physiological aspects, Biological sciences
Abstract

An analysis of pulmonary tissue response to methacholine and the influence of preferential removal of neurokinins in sensory nerve fibers by capsaicin treatment of the airway reveals that capsaicin-sensitive nerves are necessary for a portion of methacholine's airway and lung tissue effects. Anesthetized and mechanically ventilated Wistar rats are also examined.

Published
1994

38. Comparison of three methods for differential cell count in induced sputum *

Author

Saraiva-Romanholo, Beatriz M., Barnabe, Viviani, Carvalho, Ana Lucia I., Martins, Milton A., Saldiva, Paulo H.N., and Nunes, Maria do Patrocinio T.

Subjects
Inflammation -- Testing -- Research, Sputum -- Analysis -- Research -- Comparative analysis, Statistics -- Comparative analysis -- Analysis -- Research, Asthma -- Research, Health, Testing, Analysis, Research, Comparative analysis
Abstract

Background: Induced sputum (IS) using the cytospin technique has been extensively employed to characterize inflammatory airway diseases; however, procedures of cell enrichment based on cytospin increase the analytical costs and [...]

Published
2003

39. Geographic, Demographic, and Temporal Variations in the Association between Heat Exposure and Hospitalization in Brazil: A Nationwide Study between 2000 and 2015

Author

Zhao, Qi, Li, Shanshan, Coelho, Micheline S.Z.S., Saldiva, Paulo H.N., Hu, Kejia, Arblaster, Julie M., Nicholls, Neville, Huxley, Rachel R., Abramson, Michael J., and Guo, Yuming

Subjects
Economic development -- Analysis -- Brazil, Life expectancy -- Analysis, Medical care -- Analysis -- Brazil, Diabetes mellitus -- Risk factors, Parasitic diseases, Morbidity, Temperature effects, Global temperature changes, Cities and towns, Global warming, Environmental issues, Health
Abstract

Background: Limited evidence is available regarding the association between heat exposure and morbidity in Brazil and how the effect of heat exposure on health outcomes may change over time. Objectives: This study sought to quantify the geographic, demographic and temporal variations in the heat- hospitalization association in Brazil from 2000-2015. Methods: Data on hospitalization and meteorological conditions were collected from 1,814 cities during the 2000-2015 hot seasons. Quasi-Poisson regression with constrained lag model was applied to examine city-specific estimates, which were then pooled at the regional and national levels using random-effect meta-analyses. Stratified analyses were performed by sex, 10 age groups, and 11 cause categories. Meta- regression was used to examine the temporal change in estimates of heat effect from 2000 to 2015. Results: For every 5[degrees]C increase in daily mean temperature during the 2000-2015 hot seasons, the estimated risk of hospitalization over lag 0-7 d rose by 4.0% [95% confidence interval (CI): 3.7%, 4.3%] nationwide. Estimated 6.2% [95% empirical CI (eCI): 3.3%, 9.1%] of hospitalizations were attributable to heat exposure, equating to 132 cases (95% eCI: 69%, 192%) per 100,000 residents. The attributable rate was greatest in children Conclusions: In Brazil's hot seasons, 6% of hospitalizations were estimated to be attributed to heat exposure. As there was no evidence indicating that thermal adaptation had occurred at the national level, the burden of hospitalization associated with heat exposure in Brazil is likely to increase in the context of global warming. https://doi.org/10.1289/EHP3889, Introduction Brazil is the fifth most populous country and has the ninth largest economy in the world (The World Bank 2017a, 2017b). Paralleling Brazil's significant economic development over recent decades [...]

Published
2019
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40. Ambient Particulate Air Pollution and Daily Mortality in 652 Cities

Author

Liu, Cong, primary, Chen, Renjie, additional, Sera, Francesco, additional, Vicedo-Cabrera, Ana M., additional, Guo, Yuming, additional, Tong, Shilu, additional, Coelho, Micheline S.Z.S., additional, Saldiva, Paulo H.N., additional, Lavigne, Eric, additional, Matus, Patricia, additional, Valdes Ortega, Nicolas, additional, Osorio Garcia, Samuel, additional, Pascal, Mathilde, additional, Stafoggia, Massimo, additional, Scortichini, Matteo, additional, Hashizume, Masahiro, additional, Honda, Yasushi, additional, Hurtado-Díaz, Magali, additional, Cruz, Julio, additional, Nunes, Baltazar, additional, Teixeira, João P., additional, Kim, Ho, additional, Tobias, Aurelio, additional, Íñiguez, Carmen, additional, Forsberg, Bertil, additional, Åström, Christofer, additional, Ragettli, Martina S., additional, Guo, Yue-Leon, additional, Chen, Bing-Yu, additional, Bell, Michelle L., additional, Wright, Caradee Y., additional, Scovronick, Noah, additional, Garland, Rebecca M., additional, Milojevic, Ai, additional, Kyselý, Jan, additional, Urban, Aleš, additional, Orru, Hans, additional, Indermitte, Ene, additional, Jaakkola, Jouni J.K., additional, Ryti, Niilo R.I., additional, Katsouyanni, Klea, additional, Analitis, Antonis, additional, Zanobetti, Antonella, additional, Schwartz, Joel, additional, Chen, Jianmin, additional, Wu, Tangchun, additional, Cohen, Aaron, additional, Gasparrini, Antonio, additional, and Kan, Haidong, additional

Published
2019
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43. Spatial trends in congenital malformations and stream water chemistry in Southern Brazil

Author

Ibañez, Humberto C., primary, Melanda, Viviane S., additional, Gerber, Viviane K.Q., additional, Licht, Otavio A.B., additional, Ibañez, Marilea V.C., additional, Aguiar Júnior, Terêncio R., additional, Mello, Rosiane G., additional, Komechen, Heloisa, additional, Andrade, Diancarlos P., additional, Picharski, Gledson L., additional, Figueiredo, Damasio P.G., additional, Pianovski, Mara A.D., additional, Figueiredo, Mirna M.O., additional, Custódio, Gislaine, additional, Parise, Ivy Z.S., additional, Castilho, Laura M., additional, Paraizo, Mariana M., additional, Edinger, Chloe, additional, Fiori, Carmem M.C.M., additional, Pedrini, Hélio, additional, Kiesel Filho, Nilton, additional, Fabro, Ana Luiza M.R., additional, Fachin, Rayssa D., additional, Ogradowski, Karin R.P., additional, Parise, Guilherme A., additional, Saldiva, Paulo H.N., additional, Legal, Edith F., additional, Rosati, Roberto, additional, Rodriguez-Galindo, Carlos, additional, Ribeiro, Raul C., additional, Zambetti, Gerard P., additional, Lalli, Enzo, additional, and Figueiredo, Bonald C., additional

Published
2019
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44. Vesicular acetylcholine transport deficiency potentiates some inflammatory responses induced by diesel exhaust particles

Author

Santana, Fernanda P.R., primary, Pinheiro, Nathalia M., additional, Bittencourt-Mernak, Márcia I., additional, Perini, Adenir, additional, Yoshizaki, Kelly, additional, Macchione, Mariângela, additional, Saldiva, Paulo H.N., additional, Martins, Milton A., additional, Tibério, Iolanda F.L.C., additional, Prado, Marco Antônio M., additional, Prado, Vânia F., additional, and Prado, Carla M., additional

Published
2019
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45. Contributors

Author

Absher, Marlene, primary, Akesson, Bengt, additional, Altenburger, Rolf, additional, Amiard, Jean-Claude, additional, Amiard-Triquet, Claude, additional, Andersen, Melvin E., additional, Babich, H., additional, Bej, Asim K., additional, Boedeker, Wolfgang, additional, Boethling, Robert S., additional, Böhm, György M., additional, Brown, David L., additional, Cadrin, Monique, additional, Cairns, John, additional, Carson, Johnny L., additional, Castranova, Vincent, additional, Collier, Clarence R., additional, Cory-Slechta, Deborah A., additional, Craighead, John E., additional, Cuccerini, Brenda, additional, Davis, Devra Lee, additional, Domingo, José L., additional, Ducatman, Alan M., additional, Dziedzic, Daniel, additional, Elsenhans, Bernd, additional, Englande,, A.J., additional, Fan, Anna M., additional, Faust, Michael, additional, Forth, Wolfgang, additional, Frakes, Robert A., additional, Galassi, Silvana, additional, Gamble, John F., additional, Gordon, Christopher J., additional, Grant, William F., additional, Griffin, G.D., additional, Grimme, L. Horst, additional, Gross, Kenneth B., additional, Hakkinen, P.J. (Bert), additional, Hawker, Darryl, additional, Herricks, Edwin E., additional, Hicks, Lebelle R., additional, Hogan, G. Richard, additional, Hunting, Katherine, additional, Isom, Gary E., additional, Jones, Troyce D., additional, Jones, William, additional, Jori, Armanda, additional, Kagamimori, Sadanobu, additional, Kang, Han K., additional, Katoh, Terutaka, additional, Krishnan, Kannan, additional, Lebowitz, Michael D., additional, Lehnert, Bruce E., additional, Lidén, Carola, additional, Lijinsky, William, additional, Lipfert, Frederick W., additional, Lison, Dominique, additional, Lundberg, Ingvar, additional, Ma, Jane Y.C., additional, Ma, Joseph K.H., additional, Mahbubani, Meena H., additional, Massad, Eduardo, additional, McCormick, Paul V., additional, Mohler, John G., additional, Naruse, Yuchi, additional, Natarajan, A.T., additional, Obe, Günter, additional, Prasad, M. Hema, additional, Provini, Alfredo, additional, Quackenboss, James J., additional, Reddy, P.P., additional, Reuhl, Kenneth R., additional, Rose, Noel R., additional, Roth, Sheldon H., additional, Saldiva, Paulo H.N., additional, Schaeffer, David J., additional, Scheunert, Irene, additional, Schümann, Klaus, additional, Sharma, Raghubir P., additional, Shaw, Glen, additional, Simpson, Lance L., additional, Smith, Frank A., additional, Snow, Elizabeth T., additional, Sparks, Donald L., additional, Squibb, Katherine S., additional, Steinberger, Anna, additional, Stott, William T., additional, Swift, David L., additional, Testai, Emanuela, additional, Torstensson, Lennart, additional, Vittozzi, Luciano, additional, Wallace, Lance A., additional, Watson, A.P., additional, Webber, James S., additional, Welch, Laura S., additional, Wheeler, Candace S., additional, Witschi, Hanspeter, additional, and Wyzga, Ronald E., additional

Published
1993
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48. Respiratory changes due to long-term exposure to urban levels of air pollution: a histopathologic study in humans

Author

Souza, Marcelo B., Saldiva, Paulo H.N., Pope, III, C. Arden, and Capelozzi, Vera Luiza

Subjects
Respiratory tract diseases -- Risk factors, Lungs -- Environmental aspects -- Physiological aspects, Air pollution -- Physiological aspects -- Environmental aspects, Health, Physiological aspects, Risk factors, Environmental aspects
Abstract

Study objectives: To evaluate the potential associations between long-term exposure to air pollution and histopathologic evidence of damage to the lungs in humans. Design: Lung tissue samples were collected during [...]

Published
1998

50. Assessing the impact of PM2.5 on respiratory disease using artificial neural networks

Author

Polezer, Gabriela, primary, Tadano, Yara S., additional, Siqueira, Hugo V., additional, Godoi, Ana F.L., additional, Yamamoto, Carlos I., additional, de André, Paulo A., additional, Pauliquevis, Theotonio, additional, Andrade, Maria de Fatima, additional, Oliveira, Andrea, additional, Saldiva, Paulo H.N., additional, Taylor, Philip E., additional, and Godoi, Ricardo H.M., additional

Published
2018
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