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Your search keyword '"Saidel, Michael"' showing total 12 results
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12 results on '"Saidel, Michael"'

1. Feasibility of eliminating ocular chlamydia trachomatis with repeat mass antibiotic treatments

Author

Melese, Muluken, Chidambaram, Jaya Devi, Alemayehu, Wondu, Lee, David Chung, Cevallos, Vicky, Zhou, Zhaoxia, Donnellan, Cathy, Saidel, Michael, Yi, Elizabeth H., Gaynor, Bruce D., Whitcher, John P., and Lietman, Thomas M.

Subjects
Chlamydia infections -- Research, Chlamydia infections -- Drug therapy
Abstract

The rate at which chlamydial infection returns to a population after mass treatment is determined and the treatment frequency required for elimination of ocular chlamydia form a community is estimated. The result indicates that elimination of infection in a hyperendynamic area is feasible with biannual mass antibiotic administrations and attainable coverage levels.

Published
2004

11. Cataract Surgery in Uveitic Eyes.

Author

SAIDEL, MICHAEL

Subjects
CATARACT surgery, PHACOEMULSIFICATION, CRYSTALLINE lens diseases, VISUAL acuity, UVEITIS, EYE diseases
Abstract

The articles offers information on how to ensure success in cataract surgery. It states that patient selection is important in all cataract surgery because uveitic patient has unique considerations. It mentions that the single most important factor in cataract surgery in the uveitic is timing since it is greatly influenced by both patient and surgeon impatience.

Published
2011

12. Reduction of preoperative conjunctival bacterial flora with the use of mupirocin nasal ointment.

Author

Alexandrou TJ, Hariprasad SM, Benevento J, Rubin MP, Saidel M, Ksiazek S, Thompson K, Boonlayangoor S, and Mieler WF

Subjects
Adult, Aged, Aged, 80 and over, Bacteriological Techniques, Cataract Extraction, Double-Blind Method, Female, Gram-Positive Bacteria isolation & purification, Humans, Male, Middle Aged, Ointments administration & dosage, Preoperative Care, Prospective Studies, Vitrectomy, Anti-Bacterial Agents administration & dosage, Conjunctiva microbiology, Gram-Positive Bacteria growth & development, Mupirocin administration & dosage, Nasal Mucosa drug effects, Nasal Mucosa microbiology
Abstract

Purpose: To determine whether the use of mupirocin ointment for preoperative eradication of nasal bacterial carriage was effective in reducing conjunctival bacterial flora., Methods: Prospective, double-arm, blinded clinical trial of 37 eyes of 37 patients undergoing intraocular surgery (cataract extraction or pars plana vitrectomy) randomized to either control or mupirocin treatment groups. Treated patients received mupirocin nasal ointment twice daily for 5 days prior to surgery. Nasal cultures were obtained in all patients. All patients received a standard 5% povidone-iodine preparation before the surgical procedure, and conjunctival cultures were obtained in all patients before and after the povidone-iodine preparation., Results: All 37 patient nasal swabs were positive for bacterial growth (cultures were obtained prior to the use of mupirocin ointment in the treatment group). One of 15 eyes (6.7%) in the treatment group had positive conjunctival cultures prior to povidone-iodine preparation, compared with nine of 22 eyes (41%) in the control group (P < .05). Even after povidone-iodine preparation, eight of 22 eyes (36%) in the control group demonstrated persistent positive cultures, whereas one (6.7%) of the treatment eyes exhibited growth (P < .05)., Conclusions: Prophylactic use of mupirocin nasal ointment resulted in significant reduction of conjunctival flora with or without preoperative topical 5% povidone-iodine preparation. The use of mupirocin nasal ointment prior to intraocular surgery or intravitreal injections is a novel method for reducing conjunctival contamination rates, which theoretically should reduce the incidence of endophthalmitis.

Published
2006

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