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12 results on '"Sadeghi-Tari, Ali"'

3. Comparison of Iodide-125 and Ruthenium-106 Brachytherapy in the Treatment of Choroidal Melanomas

Author

Ghassemi,Fariba, Sheibani,Shahab, Arjmand,Mojtaba, Poorbaygi,Hosein, Kouhestani,Emad, Sabour,Siamak, Samiei,Farhad, Beiki-Ardakani,Akbar, Jabarvand,Mahmoud, and Sadeghi Tari,Ali

Subjects
Clinical Ophthalmology, humanities
Abstract

Fariba Ghassemi, 1–3 Shahab Sheibani, 4 Mojtaba Arjmand, 3 Hosein Poorbaygi, 4 Emad Kouhestani, 1 Siamak Sabour, 5 Farhad Samiei, 6 Akbar Beiki-Ardakani, 7 Mahmood Jabarvand, 1 Ali Sadeghi Tari 1 1Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IR, Iran; 2Retina & Vitreous Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IR, Iran; 3Ocular Oncology Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IR, Iran; 4Radiation Application Research School, Nuclear Science and Technology Research Institute, Tehran, Iran; 5Safety Promotion and Injury Prevention Research Centre, Department of Clinical Epidemiology, School of Health,Shahid Beheshti University of Medical Sciences, Tehran, IR, Iran; 6Radiation Oncology Department, Cancer Institute, Imam Hospital and Medical Complex, Tehran University of Medical Sciences, Tehran, Iran; 7Radiation Physics Department, Princess Margaret Hospital, Toronto, ON, CanadaCorrespondence: Fariba GhassemiEye Research Center, Farabi Eye Hospital, Qazvin Square, Tehran 1336616351, IranTel +98-21-55421006Fax +98-21-55416134Email fariba.ghassemi@gmail.comBackground: To compare iodine-125 ( 125I) with ruthenium-106 ( 106Ru) episcleral plaque radiation therapy in terms of the effectiveness and non-inferiority for choroidal melanoma treatment.Objective: To report the non-inferiority of new made iodine-125 ( 125I) compared with ruthenium-106 ( 106Ru) episcleral plaque radiation.Patients and Methods: A retrospective, non-randomized comparative case series. In this series the patients treated with 125I and 106Ru episcleral plaques for choroidal melanoma between September 2013 and August 2017 at Farabi Hospital are compared. Local control of choroidal melanomas after 125I and 106Ru plaques implantation and vision changes are the main outcome measures.Results: A total of 35 patients were identified ( 125I = 15, 106Ru = 20). No significant difference between two groups in visual acuity, diameter and thickness changes were observed after treatment. Multivariate linear regression (MLR) analysis showed that final diameter was only, independently and significantly, correlated with the pre-treatment diameter of the tumor (β =  0.59, 95% confidence interval [CI]: 0.29, 1.34, P =  0.003). The same MLR analysis for the final thickness and visual acuity, after adjusting for age and sex showed no significant difference between two groups. A single patient treated with 106Ru had local tumor recurrence with no one in the 125I group. No statistical difference in the rate of ocular complications was observed.Conclusion: The treatment with our 125I plaques is as effective as 106Ru plaques in controlling choroidal melanoma tumor and preserving the vision during the two and half year of follow-up. The complication rates are alike. It means that the effectiveness of 125I is not only comparable to 106Ru but also superior when the outcome of the interest is the thickness of the tumors.Keywords: brachytherapy, choroidal melanoma, complication, local tumor control, 125I, radiation, 106Ru, tumor size, vision preservation

Published
2020

7. Color Doppler imaging of orbital vasculature before and after orbital decompression in thyroid eye disease.

Author

Jamshidian-Tehrani, Mansooreh, Nekoozadeh, Shahbaz, Alami, Elham, Ghadimi, Hadi, Nabavi, Amin, Ameli, Kambiz, Sharif Kashani, Shervin, Kashkouli, Mohsen Bahmani, and Sadeghi-Tari, Ali

Subjects
THYROID eye disease, RETINAL artery, BLOOD vessels, OPHTHALMIC artery, EYE examination
Abstract

Purpose: To measure alterations in orbital blood flow parameters using color Doppler imaging (CDI) before and after orbital decompression in patients with moderate to severe thyroid eye disease (TED). Methods: Resistance index (RI) and maximum and minimum velocity of ophthalmic artery (OA), superior ophthalmic vein (SOV), and central retinal artery (CRA) of 24 eyes (14 patients) with TED were measured before and at least 3 months after cosmetic orbital decompression procedure (single or double walls) using CDI. Complete eye examination was performed to define the severity (EUGOGO classification) and activity (clinical activity score) of TED. Results: Median OA (p = 0.003) and CRA (p = 0.001) resistance indices were significantly reduced postoperatively. Significant differences were found in maximum (p = 0.001) and minimum (p = 0.014) velocity of SOV before and after surgery. While a significant decrease in exophthalmometry was observed after the orbital decompression (p = 0.031), intraocular pressure changes were not significant (p = 0.182). Conclusion: Orbital decompression procedure led to a significant reduction of RI in both CRA and OA in patients with TED. [ABSTRACT FROM AUTHOR]

Published
2019
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11. Ocular movement disorders and extraocular muscle involvement in Iranian Graves' ophthalmopathy patients.

Author

K-Jafari A, Sadeghi-Tari A, Minaee-Noshahr N, Ameri A, Anvari F, Ali-Mahmoudi A, Eshraghi B, Rajabi MB, and Rajabi MT

Subjects
Adolescent, Adult, Aged, Female, Graves Ophthalmopathy diagnostic imaging, Humans, Iran, Male, Middle Aged, Ocular Motility Disorders diagnostic imaging, Oculomotor Muscles diagnostic imaging, Tomography, X-Ray Computed, Graves Ophthalmopathy complications, Ocular Motility Disorders etiology, Oculomotor Muscles pathology
Abstract

Purpose: The aim of this study was to evaluate movement disorder patterns and extraocular muscle involvement in Iranian Graves' Ophthalmopathy (GO) patients., Methods: We examined 75 patients (37 women and 38 men) with GO. Female to male ratio was 0.97 among all patients and 0.72 among restrictive myopathic cases (male 18(58.1%), female 13 (41.9%), P=0.2). Their age ranged from 16 to 66 years; mean age was 35.42+/-11.63 and 33.55+/-10,.31 among patients affected by restrictive enlargement and who did not, respectively., Results: Orbital CT assessment showed EOM enlargement in 124 out of 150 orbits (82.6%). clinical restriction was evident in 31 (41.3%) out of 75 patients. Bilateral restriction was observed in 14 out of 31 (45.1%). The most frequent type of movement limitation was supraduction limitation followed by abduction, inferaduction, and adduction limitations (59%, 40%, 31.1% and 13.3% respectively). This was compatible with Hess screen results and orbital CT reports in regard of IR, MR, SR and LR involvement. Sixteen out of 75 patients reported diplopia. Mean Hertel exophthalmometry readings were higher in eyes with restrictive myopathy., Conclusion: This study showed more restrictive myopathy in cases with more extraocular enlargement and positive correlation between severity of inferior rectus enlargement and Hertel reading. A higher rate of male patients in our study may be due to ethnic differences in GO in Iranian patients or due to severity of involvement in this group.

Published
2010

12. Photoclinic. Dermoid cyst.

Author

Sadeghi-Tari A, Rajabi MT, Tabatabaie SZ, Kasai A, and Akbari MR

Subjects
Adolescent, Dermoid Cyst pathology, Dermoid Cyst surgery, Diagnosis, Differential, Humans, Male, Orbital Neoplasms pathology, Orbital Neoplasms surgery, Dermoid Cyst diagnosis, Orbital Neoplasms diagnosis
Published
2008
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