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Your search keyword '"Sadat Mansouri, Saeed"' showing total 2 results
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2 results on '"Sadat Mansouri, Saeed"'

1. An in vitro study on the effects of photobiomodulation by diode lasers (red, infrared, and red–infrared combination) on periodontal ligament mesenchymal stem cells treated with bisphosphonates.

Author

Safari, Amir Hossein, Sadat Mansouri, Saeed, Iranpour, Babak, Hodjat, Mahshid, and Hakimiha, Neda

Subjects
*MESENCHYMAL stem cells, *TREATMENT effectiveness, *SEMICONDUCTOR lasers, *PERIODONTAL ligament, *DIAGNOSTIC use of polymerase chain reaction
Abstract

This study evaluated the effect of photobiomodulation therapy (PBMT) using 660 and 808 nm diode lasers (individual and in combination) on periodontal ligament mesenchymal stem cells (PDLSCs) in the presence of zoledronic acid (ZA). PDLSCs were cultured for 48 h in DMEM complete medium containing 5 μM ZA. PBMT was done three times with a 24‐h interval in groups 1 (660 nm, 5 J/cm2), 2 (880 nm, 3 J/cm2), and 3 (660 + 808 nm) either in normal or ZA‐treated culture medium. Control groups did not receive PBMT. Twenty‐four hours post‐irradiation, cell proliferation and expression of RANKL and OPG were assessed using MTT and real‐time PCR tests, respectively. The results showed a significant decrease in cell viability in ZA‐treated cells (p < 0.001). Additionally, ZA induced the expression of OPG (p = 0.03) while reducing RANKL (p < 0.001). Cell proliferation was significantly increased in 808 and 660 + 808 nm groups. Moreover, all PBMT groups could significantly increase and decrease the RANKL and OPG, respectively, in the presence of ZA (all p < 0.001). A combination of 660 + 808 nm showed the highest effects on both genes. In conclusion, it seems that PBMT can modulate the effects of ZA by inducing PDLSC proliferation and increasing RANKL‐to‐OPG gene expression ratio. [ABSTRACT FROM AUTHOR]

Published
2024
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2. Clinical and Radiographic Evaluation of the Effect of Bovine-derived Hydroxyapatite (Bio-Oss®) and A Synthetic HA/β-TCP (Osteon®) in the Treatment of Class II Furcation Defects in Mandibular Molars

Author

Karimi, Mohammad Reza, Sadat Mansouri, Saeed, and Abdolkarimpour, Zahra

Subjects
610 Medical sciences, Medicine
Abstract

Background and aims. There are some studies comparing bone replacement grafts. The aim of this study wasclinical evaluation of the effect of Osteon® (as a new bone material) and Bio-Oss® (Bovine-derived hydroxyapatite) in the treatment of mandibular molar class II furcation defects in humans. Materials and methods. Eleven patients (10 females and 1 male, age range of 27-59 years ; mean age of 45.5±11.8 years) who had at least 22 mandibular class II buccal or lingual furcation defects were treated either with Osteon (as the case group) or Bio-Oss (as the control group). Each defect was randomly assigned to either the case group or the control group. Clinical parameters and the soft tissue and hard tissue measurements, including plaque index (PI), gingival index (GI), gingival reces-sion of furcation area (GR), pocket depth (PD), clinical attachment level (CAL), horizontal defect depth (HDD), vertical defect depth (VDD) were recorded at baseline and six months after surgery. Data were analyzed using t-test or Wilcoxon's test. Results. Similar healing results were observed for both treatments. The results showed significant probing depth reduction(case group: 0.77 mm and control group: 0.84 mm) and HDD reduction (case group: 0.51 mm and control group: 0.8 mm) and PI reduction. There was not statistically significant difference between the groups in all soft and hard tissue parameters. Conclusion. The results of this study showed that the effect of using Osteon as a bone graft material is the same as thatof Bio-Oss in the treatment of mandibular class II furcation defects., Journal of Periodontology & Implant Dentistry; ISSN 2008-7748

Published
2011
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