337 results on '"Sacks, David L."'
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2. Resilience of dermis resident macrophages to inflammatory challenges
3. Dermis resident macrophages orchestrate localized ILC2 eosinophil circuitries to promote non-healing cutaneous leishmaniasis
4. Single-cell atlas of Leishmania development in sandflies reveals the heterogeneity of transmitted parasites and their role in infection.
5. Inflammasomes and Leishmania: in good times or bad, in sickness or in health
6. First evidence of experimental genetic hybridization between cutaneous and visceral strains of Leishmania donovani within its natural vector Phlebotomus argentipes
7. The Role of Antigen and IL-12 in Sustaining Th1 Memory Cells in vivo: IL-12 Is Required to Maintain Memory/Effector Th1 Cells Sufficient to Mediate Protection to an Infectious Parasite Challenge
8. Delayed-Type Hypersensitivity to Phlebotomus papatasi Sand Fly Bite: An Adaptive Response Induced by the Fly?
9. The Role of Phosphoglycans in Leishmania-Sand Fly Interactions
10. Persistence without Pathology in Phosphoglycan-Deficient Leishmania major
11. Cross-species genetic exchange between visceral and cutaneous strains of Leishmania in the sand fly vector
12. Experimental Hybridization in Leishmania: Tools for the Study of Genetic Exchange
13. Demonstration of Genetic Exchange during Cyclical Development of Leishmania in the Sand Fly Vector
14. Vaccines Against Parasites
15. Contributors
16. Stage-Specific Adhesion of Leishmania Promastigotes to the Sandfly Midgut
17. Evidence that the Vectorial Competence of Phlebotomine Sand Flies for Different Species of Leishmania is Controlled by Structural Polymorphisms in the Surface Lipophosphoglycan
18. Suppression of Immune Responses to Protozoan Parasites
19. Splenic Cytokine Responses in Indian Kala-Azar before and after Treatment
20. Vaccines against tropical parasitic diseases: a persisting answer to a persisting problem
21. Protein methyltransferase 7 deficiency in Leishmania major increases neutrophil associated pathology in murine model
22. A role for insect galectins in parasite survival
23. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
24. Leishmania Sexual Reproductive Strategies as Resolved through Computational Methods Designed for Aneuploid Genomes
25. Host and Parasite Factors Influencing the Expression of Cutaneous Leishmaniasis
26. Sand Fly (Phlebotomus papatasi) Embryo Microinjection for CRISPR/Cas9 Mutagenesis
27. The Null Hypothesis of IFN-γ and Monocyte Function in Leishmaniasis
28. Fatal progression of experimental visceral leishmaniasis is associated with intestinal parasitism and secondary infection by commensal bacteria, and is delayed by antibiotic prophylaxis
29. M2-like, dermal macrophages are maintained via IL-4/CCL24–mediated cooperative interaction with eosinophils in cutaneous leishmaniasis
30. Control of Leishmania–Sand Fly Interactions by Polymorphisms in Lipophosphoglycan Structure
31. Identification of an Infective Stage of Leishmania Promastigotes
32. Evidence that the vectorial competence of phlebotomine sand flies for different species of Leishmania is controlled by structural polymorphisms in the surface lipophosphoglycan
33. Skin-Derived Macrophages from Leishmania major-Susceptible Mice Exhibit Interleukin-12- and Interferon-γ-Independent Nitric Oxide Production and Parasite Killing After Treatment with Immunostimulatory DNA
34. Comparison of the A2 Gene Locus in Leishmania donovani and Leishmania major and Its Control over Cutaneous Infection
35. Stage-specific adhesion of Leishmania promastigotes to the sandfly midgut
36. Immunological and pathological evaluation of rhesus macaques infected with Leishmania major
37. CRISPR/Cas9 Mutagenesis in Phlebotomus papatasi: the Immune Deficiency Pathway Impacts Vector Competence for Leishmania major
38. Development of a Natural Model of Cutaneous Leishmaniasis: Powerful Effects of Vector Saliva and Saliva Preexposure on the Long-Term Outcome of Leishmania major Infection in the Mouse Ear Dermis
39. Uptake of Leishmania major Amastigotes Results in Activation and Interleukin 12 Release from Murine Skin-derived Dendritic Cells: Implications for the Initiation of Anti-Leishmania Immunity
40. Targeted gene deletion of Leishmania major genes encoding developmental stage-specific leishmanolysin (GP63)
41. Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor
42. Vaccination with DNA Encoding the Immunodominant LACK Parasite Antigen Confers Protective Immunity to Mice Infected with Leishmania major
43. Memory may not need reminding
44. Leishmania Promastigotes Selectively Inhibit Interleukin 12 Induction in Bone Marrow-derived Macrophages from Susceptible and Resistant Mice
45. Skin Dendritic Cells in Murine Cutaneous Leishmaniasis
46. In Vivo Cytokine Profiles in Patients with Kala-azar: Marked Elevation of Both Interleukin-10 and Interferon-gamma
47. Drug Discovery for Kinetoplastid Diseases: Future Directions
48. Chapter 17 - Vaccines Against Parasites
49. Inhibition of host cell signal transduction by Leishmania: observations relevant to the selective impairment of IL-12 responses
50. NOX2-Derived Reactive Oxygen Species Control Inflammation during Leishmania amazonensis Infection by Mediating Infection-Induced Neutrophil Apoptosis
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