1. Non-surgical periodontal therapy supplemented with systemically administered azithromycin: a systematic review of RCTs
- Author
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Sabrina Lill Buset, Nicola U. Zitzmann, Roland Weiger, and Clemens Walter
- Subjects
medicine.medical_specialty ,Periodontal treatment ,medicine.drug_class ,business.industry ,Antibiotics ,Azithromycin ,medicine.disease ,Chronic periodontitis ,law.invention ,Surgery ,Randomized controlled trial ,law ,Internal medicine ,medicine ,Aggressive periodontitis ,Humans ,Periodontal Debridement ,Adverse effect ,business ,Periodontitis ,General Dentistry ,medicine.drug ,Randomized Controlled Trials as Topic - Abstract
Background: Azithromycin may be an alternative adjunctive systemic antibiotic in non-surgical periodontal therapy. Objective: This study aims to identify randomized controlled trials evaluating non-surgical periodontal treatment of chronic and/or aggressive periodontitis supplemented with systemically administered azithromycin. Materials and methods: A systematic literature search was performed for publications published by 31 March 2014 using electronic databases and hand search. Randomized controlled trials published in English or German language, with a follow-up ≥6months were included. From 231 titles identified, nine publications were eligible for inclusion. Results: Among the studies included, showing some risk of bias, seven reported on patients with chronic periodontitis and two with aggressive periodontitis. Minor adverse events were described in five studies. A synthesis of results using a vote counting method was applied. Significant (p
- Published
- 2021