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Background: Given the increasing rate of infections following hip arthroplasty, one of the current options is the application of a biocomposite at the site of the infection. One of the products used is Stimulan, a completely resorbable calcium sulfate, designed to treat acute and chronic infections. This biocomposite has a controlled purity, is easy to mix with liquid, powder, and antibiotics, and can be applied directly to the site of infection, or it can be injected. Methods: We analyzed data from 76 patients, who were admitted to the County Clinical Hospital of Emergency "St. Apostol Andrei" in Galati during January 2017–September 2023, with a diagnosis of infection associated with hip arthroplasty. Results: In 69.73% of cases (52 patients), we decided to keep the implant in place. In this subgroup, Stimulan was applied in 26 cases (57.78%). Of these, 100% were cured—compared to the subgroup in which Stimulan was not applied, where this percentage was lower. All patients underwent chemical and mechanical toileting, and for 24 patients (20.27%), it was necessary to ablate the implant with or without the application of Stimulan, then reimplantation of the prosthesis. Conclusions: The patients with Stimulan had a longer average length of hospitalization, almost half of them required intervention in two periods, and a quarter required the implantation of spacers. However, the cure rate was higher, only in three people could we not control the infection, and there was no death. This study confirms the effectiveness of the treatment when using a biocomposite in addition to the classical treatment for both acute and chronic cases. [ABSTRACT FROM AUTHOR]

The influence of vibrations on the position of the target in the interaction chamber of the ELI-NP facility represents an important element in any experiment with gamma beam rays. Also, several detection systems are provided around the interaction chamber for tracking the nuclear reactions that occur inside the interaction chamber. They are fixed with very high precision in relation to the interaction chamber. In addition to tracking the gamma ray beam, it must to know with great precision the position of the sample holder and of these detectors placed in laboratory. The precision required for a gamma-ray experiment is determined by the size of the studied material. If there is enough target material, then the precision is not important, but if we have a very small amount of material, then precision becomes significant. For a common experiment, accuracy is considered satisfactory for a value of 2µm. The paper analyzes the influence of anthropogenic and natural vibrations on the position of the target, located at the end of a guide beam. [ABSTRACT FROM AUTHOR]

Heterotopic ossification is defined as the presence of mature lamellar bone in soft tissues such as muscles, tendons, skin or organs, where bone normally doesn't exist. It can appear more frequent as a complication following central nervous system disorder s like acute brain injuries, brain tumors or spinal cord injuries, or following burns, hip and elbow surgery. For heterotopic bone formation some local and general specific conditions are necessary. The three main conditions are: presence of a morphogenetic induction agent, mesenchymal progenitor stem cells and a permissive local and general environment. [ABSTRACT FROM AUTHOR]

Heterotopic ossification is defined as abnormal bone formation in extraskeletal soft tissues where bone normally does not exist, for example muscles tendons, skin and organs. In the last decades a great interest of this pathology was given to the heterotopic ossification what occur after hip replacement operations. This is due to the gradual increase in the frequency of such interventions and repercussions that this condition untreated may have. The two current main prophylactic methods widely used for heterotopic ossification prophylaxis are radiation therapy which can be used either preoperatively or postoperatively and prophylaxis with NSAIDs. Both prophylaxis methods can be effective but they can lead to some adverse effects to the patient. [ABSTRACT FROM AUTHOR]