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26 results on '"Sabino, Caetano Padial"'

6. Molecular Damage

Author

Sabino, Caetano Padial, Hamblin, Michael Richard, Sellera, Fábio Parra, editor, Nascimento, Cristiane Lassálvia, editor, and Ribeiro, Martha Simões, editor

Published
2016
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7. Photosensitizers

Author

Hamblin, Michael Richard, Sabino, Caetano Padial, Sellera, Fábio Parra, editor, Nascimento, Cristiane Lassálvia, editor, and Ribeiro, Martha Simões, editor

Published
2016
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8. Multimodality Dosimetry

Author

Ribeiro, Martha Simões, Sabino, Caetano Padial, Sellera, Fábio Parra, editor, Nascimento, Cristiane Lassálvia, editor, and Ribeiro, Martha Simões, editor

Published
2016
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9. Cellular Damage

Author

Sabino, Caetano Padial, Hamblin, Michael Richard, Sellera, Fábio Parra, editor, Nascimento, Cristiane Lassálvia, editor, and Ribeiro, Martha Simões, editor

Published
2016
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10. Systemic Effects

Author

Hamblin, Michael Richard, Sabino, Caetano Padial, Sellera, Fábio Parra, editor, Nascimento, Cristiane Lassálvia, editor, and Ribeiro, Martha Simões, editor

Published
2016
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12. History of PDT

Author

Sellera, Fábio Parra, Sabino, Caetano Padial, Hamblin, Michael Richard, Sellera, Fábio Parra, editor, Nascimento, Cristiane Lassálvia, editor, and Ribeiro, Martha Simões, editor

Published
2016
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13. Other Practices in PDT

Author

Sellera, Fábio Parra, Pogliani, Fabio Celidonio, Sabino, Caetano Padial, Sellera, Fábio Parra, editor, Nascimento, Cristiane Lassálvia, editor, and Ribeiro, Martha Simões, editor

Published
2016
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14. Future Perspectives

Author

Sellera, Fábio Parra, Nascimento, Cristiane Lassálvia, Pogliani, Fabio Celidonio, Sabino, Caetano Padial, Ribeiro, Martha Simões, Sellera, Fábio Parra, editor, Nascimento, Cristiane Lassálvia, editor, and Ribeiro, Martha Simões, editor

Published
2016
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21. Photodynamic therapy for pododermatitis in penguins

Author

Sellera, Fábio Parra, primary, Sabino, Caetano Padial, additional, Ribeiro, Martha Simões, additional, Fernandes, Loriê Tukamoto, additional, Pogliani, Fabio Celidonio, additional, Teixeira, Carlos Roberto, additional, Dutra, Gustavo Henrique Pereira, additional, and Nascimento, Cristiane Lassálvia, additional

Published
2014
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24. Colaboradores

Author

Fernandes, Adjaci Uchôa, Lima Fujita, Alessandra Keiko, Baptista, Alessandra, Costa Mota, Ana Carolina, Pavarina, Ana Claudia, Barcessat, Ana Rita Pinheiro, Tedesco, Antonio Claudio, Jorge, Antonio Olavo Cardoso, Sabino, Caetano Padial, Pereira, Cristiane Aparecida, Ghosal, Debnath, Selera, Debora Parra, Martinez, Elizabeth Ferreira, Mima, Ewerton Garcia de Oliveira, Kato, Ilka Tiemy, Freire, Fernanda, Jensen, Grant J., Junqueira, Juliana Campos, Chaves Rojz, Juliana Castilho, Marotti, Juliana, Silva, Juliana Pedreira, Paula, Leonardo Barcelos de, Theodoro, Leticia Helena, Figueiredo Godoi, Lívia Mara Alves, Corrêa, Luciana, Suzuki, Luis Cláudio, Leal Gonçalves, Marcela Letícia, Wainwright, Mark, Baptista, Mauricio S., Hamblin, Michael R., Kaplan, Mohammed, Barros, Patrícia Pimentel de, Prates, Renato Araujo, Rossoni, Rodnei Dennis, Lizarelli, Rosane de Fátima Zanirato, Itri, Rosângela, Bussadori, Sandra Kalil, Sharma, Sulbha K., Garcia, Valdir Gouveia, Bagnato, Vanderlei Salvador, and Miyakawa, Walter

Published
2019
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25. Colaboradores

Author

Baptista, Alessandra, de Souza, Ana Maria Aparecida, de Freitas, Anderson Zanardi, Sabino, Caetano Padial, Yamashita, Carolina, Meneguzzo, Daiane Thaís, Laganá, Dalva Cruz, de Fátima Teixeira da Silva, Daniela, Zezell, Denise Maria, de Paula Eduardo, Fernanda, Nogueira, Gesse Eduardo Calvo, Suzuki, Hideo, Kato, Ilka Tiemy, Ferreira, Leila Soares, Bezinelli, Letícia Mello, Almeida-Lopes, Luciana, Corrêa, Luciana, Azevedo, Luciane Hiramatsu, Suzuki, Luís Cláudio, Marques, Márcia Martins, Moreira, Maria Stella N.A., Hamblin, Michael R., Prates, Renato Araújo, de Fátima Zanirato Lizarelli, Rosane, Cordon, Rosely, Suzuki, Selly Sayuri, de Oliveira Leite, Thales Ferrari, Bagnato, Vanderlei Salvador, and Huang, Ying-Ying

Published
2012
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26. Antimicrobial Photodynamic Inactivation Inhibits Candida albicansVirulence Factors and Reduces In VivoPathogenicity

Author

Kato, Ilka Tiemy, Prates, Renato Araujo, Sabino, Caetano Padial, Fuchs, Beth Burgwyn, Tegos, George P., Mylonakis, Eleftherios, Hamblin, Michael R., and Ribeiro, Martha Simões

Abstract

ABSTRACTThe objective of this study was to evaluate whether Candida albicansexhibits altered pathogenicity characteristics following sublethal antimicrobial photodynamic inactivation (APDI) and if such alterations are maintained in the daughter cells. C. albicanswas exposed to sublethal APDI by using methylene blue (MB) as a photosensitizer (0.05 mM) combined with a GaAlAs diode laser (λ 660 nm, 75 mW/cm2, 9 to 27 J/cm2). In vitro, we evaluated APDI effects on C. albicansgrowth, germ tube formation, sensitivity to oxidative and osmotic stress, cell wall integrity, and fluconazole susceptibility. In vivo, we evaluated C. albicanspathogenicity with a mouse model of systemic infection. Animal survival was evaluated daily. Sublethal MB-mediated APDI reduced the growth rate and the ability of C. albicansto form germ tubes compared to untreated cells (P< 0.05). Survival of mice systemically infected with C. albicanspretreated with APDI was significantly increased compared to mice infected with untreated yeast (P< 0.05). APDI increased C. albicanssensitivity to sodium dodecyl sulfate, caffeine, and hydrogen peroxide. The MIC for fluconazole for C. albicanswas also reduced following sublethal MB-mediated APDI. However, none of those pathogenic parameters was altered in daughter cells of C. albicanssubmitted to APDI. These data suggest that APDI may inhibit virulence factors and reduce in vivopathogenicity of C. albicans. The absence of alterations in daughter cells indicates that APDI effects are transitory. The MIC reduction for fluconazole following APDI suggests that this antifungal could be combined with APDI to treat C. albicansinfections.

Published
2012
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