Search

Your search keyword '"Sabine Vogel"' showing total 46 results
Start Over Author "Sabine Vogel"
46 results on '"Sabine Vogel"'

1. Cardiomyocyte-Specific Transgenic Expression of Prolyl-4-Hydroxylase Domain 3 Impairs the Myocardial Response to Ischemia

Author

Anke Zieseniss, Amke R. Hesse, Aline Jatho, Sabine Krull, Marion Hölscher, Sabine Vogel, and Dörthe M. Katschinski

Subjects
Hypoxia, Hypoxia-inducible factor, Ischemia, Heart, PHD3, Physiology, QP1-981, Biochemistry, QD415-436
Abstract

Aims: The prolyl-4-hydroxylase domain (PHD) enzymes are representing novel therapeutic targets for ischemic tissue protection. Whereas the consequences of a knock out of the PHDs have been analyzed in the context of cardioprotection, the implications of PHD overexpression is unknown so far. Methods and Results: We generated cardiomyocyte-specific PHD3transgenic mice (cPhd3tg). Resting cPhd3tg mice did not show constitutive accumulation of HIF-1α or HIF-2α or changes in HIF target gene expression in the heart. Cardiac function was followed up for 14 months in these mice and found to be unchanged. After challenging the cPhd3tg mice with ligation of the left anterior descending artery, HIF-1α/-2α accumulation in the left ventricles was blunted. This was associated with a significantly increased infarct size of the cPhd3tg compared to wild type mice. Conclusion: Whereas overexpression of PHD3 in the resting state does not significantly influence cardiac function, it is crucial for the cardiac response to ischemia by affecting HIFα accumulation in the ischemic tissue.

Published
2015
Full Text
View/download PDF

2. Hypoxia modulates fibroblastic architecture, adhesion and migration: a role for HIF-1α in cofilin regulation and cytoplasmic actin distribution.

Author

Melanie Vogler, Sabine Vogel, Sabine Krull, Katja Farhat, Pia Leisering, Susanne Lutz, Christina M Wuertz, Dörthe M Katschinski, and Anke Zieseniss

Subjects
Medicine, Science
Abstract

Cells can adapt to hypoxia by various mechanisms. Yet, hypoxia-induced effects on the cytoskeleton-based cell architecture and functions are largely unknown. Here we present a comprehensive analysis of the architecture and function of L929 fibroblasts under hypoxic conditions (1% O2). Cells cultivated in hypoxia showed striking morphological differences as compared to cells cultivated under normoxic conditions (20% O2). These changes include an enlargement of cell area and volume, increased numbers of focal contacts and loss of cell polarization. Furthermore the β- and γ-actin distribution is greatly altered. These hypoxic adjustments are associated with enhanced cell spreading and a decline of cell motility in wound closure and single cell motility assays. As the hypoxia-inducible factor-1α (HIF-1α) is stabilised in hypoxia and plays a pivotal role in the transcriptional response to changes in oxygen availability we used an shRNA-approach to examine the role of HIF-1α in cytoskeleton-related architecture and functions. We show that the observed increase in cell area, actin filament rearrangement, decrease of single cell migration in hypoxia and the maintenance of p-cofilin levels is dependent on HIF-1α stabilisation.

Published
2013
Full Text
View/download PDF

5. Das akute idiopathische Skrotalödem – eine relevante Differenzialdiagnose des akuten Skrotums im Kindes- und Jugendalter

Author

Wolfgang Rösch, Sabine Vogel, and Franziska Vauth

Subjects
Gynecology, medicine.medical_specialty, business.industry, 030232 urology & nephrology, Testicular pain, 030208 emergency & critical care medicine, Acute scrotum, medicine.disease, Testicular trauma, Pediatric urology, 03 medical and health sciences, 0302 clinical medicine, Pediatrics, Perinatology and Child Health, Hydrocele, medicine, Testicular torsion, medicine.symptom, Epididymitis, business, Idiopathic scrotal edema
Abstract

Hintergrund Das „akute Skrotum“ ist ein haufiger kinderurologischer Notfall, der eine rasche Beurteilung zur Diagnose bzw. zum Ausschluss einer Hodentorsion erfordert. Zu den weniger bekannten Differenzialdiagnosen zahlt das idiopathische Skrotalodem (AISE). In dieser Studie beschreiben wir Haufigkeit und klinisches Management des AISE in unserer Klinik. Patienten 319 Patienten im Alter von 0 bis 17 Jahren, die zwischen 01/2013 bis 12/2017 in der kinderurologischen Klinik der KUNO-Kinderklinik St. Hedwig Regensburg mit der Diagnose „akutes Skrotum“ behandelt wurden. Methode Retrospektive Analyse der Patientenakten. Ergebnisse 234/319 Patienten wurden ambulant und 85/319 (27%) stationar behandelt. Bei 23/319 (7,2%) wurde ein AISE diagnostiziert. Alle Patienten mit AISE wurden ambulant behandelt, bei keinem dieser Patienten musste eine operative Exploration erfolgen. Weitere Diagnosen der ambulanten Patienten: Epididymitis (87/234; 37%), Hydatidentorsion (42/234; 18%), Hodentorsion (5/234; 2%) Hodentrauma (10/234; 4%), Hydrozele (9/234; 4%), unspezifische Hodenschmerzen (58/234; 25%). Diagnosen der stationaren Patienten: Hodentorsion (58/85; 68%), Hydatidentorsion (17/85; 20%), Epididymitis (8/85; 9%), Hodentrauma (1/85; 1%), Tumor (1/85; 1%). Diskussion Das AISE ist eine Ausschlussdiagnose mit typischem klinischem Bild. Zusammen mit dem charakteristischen Befund in der (Doppler-) Sonografie ist eine sichere Abgrenzung zu anderen Differenzialdiagnosen des akuten Skrotums moglich. Durch die korrekte Diagnosestellung konnen unnotige Klinikaufenthalte, Operationen und medikamentose Behandlungen vermieden werden. Schlussfolgerung Das AISE ist eine relevante Differentialdiagnose des akuten Skrotums, das Kinder- und Jugendarzten bekannt sein sollte. Background The diagnosis “acute scrotum” constitutes a frequent urgency in pediatric urology requiring rapid evaluation to rule out testicular torsion. Acute idiopathic scrotal edema (AISE) is a less known differential diagnosis of acute scrotum. In this study we aimed to describe prevalence and clinical management of children and adolescents with AISE treated in our clinic. Patients 319 patients at the age of 0 to 17 years with the diagnosis of acute scrotum treated in the clinic of pediatric urology Regensburg between 01/2013 and 12/2017 were included. Method Retrospective charts analysis. Results 234/319 patients were treated as outpatients and 85/319 (27%) as inpatients. Diagnosis of AISE was made in 23/319 (7.2%) individuals. All of them were managed as outpatients and none received surgical exploration. Further diagnoses of outpatients: epididymitis (87/234; 37%); appendix testes torsion (42/234; 18%); testicular torsion (5/234; 2%); testicular trauma (10/234; 4%); hydrocele (9/234; 4%); nonspecific testicular pain (58/234; 25%). Diagnoses of inpatients: testicular torsion (58/85; 68%); appendix testes torsion (17/85; 20%); epididymitis (8/85; 9%); testicular trauma (1/85; 1%); tumor (1/85; 1%). Discussion In the differential diagnosis of acute scrotum the typical clinical presentation and the characteristic (Doppler) ultrasound findings allow the reliable diagnosis of AISE. Correct and prompt AISE diagnosis helps to avoid unnecessary hospitalizations, surgeries and medications. Conclusion Pediatricians should be familiar with AISE as a differential diagnosis of acute scrotum.

Published
2020

7. [Acute Idiopathic Scrotal Edema - A Relevant Differential Diagnosis of the Acute Scrotum in Childhood and Adolescence]

Author

Sabine, Vogel, Franziska, Vauth, and Wolfgang, Rösch

Subjects
Diagnosis, Differential, Male, Adolescent, Liver Diseases, Acute Disease, Scrotum, Edema, Humans, Genital Diseases, Male
Abstract

Das „akute Skrotum“ ist ein häufiger kinderurologischer Notfall, der eine rasche Beurteilung zur Diagnose bzw. zum Ausschluss einer Hodentorsion erfordert. Zu den weniger bekannten Differenzialdiagnosen zählt das idiopathische Skrotalödem (AISE). In dieser Studie beschreiben wir Häufigkeit und klinisches Management des AISE in unserer Klinik.319 Patienten im Alter von 0 bis 17 Jahren, die zwischen 01/2013 bis 12/2017 in der kinderurologischen Klinik der KUNO-Kinderklinik St. Hedwig Regensburg mit der Diagnose „akutes Skrotum“ behandelt wurden.Retrospektive Analyse der Patientenakten.234/319 Patienten wurden ambulant und 85/319 (27%) stationär behandelt. Bei 23/319 (7,2%) wurde ein AISE diagnostiziert. Alle Patienten mit AISE wurden ambulant behandelt, bei keinem dieser Patienten musste eine operative Exploration erfolgen. Weitere Diagnosen der ambulanten Patienten: Epididymitis (87/234; 37%), Hydatidentorsion (42/234; 18%), Hodentorsion (5/234; 2%) Hodentrauma (10/234; 4%), Hydrozele (9/234; 4%), unspezifische Hodenschmerzen (58/234; 25%). Diagnosen der stationären Patienten: Hodentorsion (58/85; 68%), Hydatidentorsion (17/85; 20%), Epididymitis (8/85; 9%), Hodentrauma (1/85; 1%), Tumor (1/85; 1%).Das AISE ist eine Ausschlussdiagnose mit typischem klinischem Bild. Zusammen mit dem charakteristischen Befund in der (Doppler-) Sonografie ist eine sichere Abgrenzung zu anderen Differenzialdiagnosen des akuten Skrotums möglich. Durch die korrekte Diagnosestellung können unnötige Klinikaufenthalte, Operationen und medikamentöse Behandlungen vermieden werden.Das AISE ist eine relevante Differentialdiagnose des akuten Skrotums, das Kinder- und Jugendärzten bekannt sein sollte.The diagnosis “acute scrotum” constitutes a frequent urgency in pediatric urology requiring rapid evaluation to rule out testicular torsion. Acute idiopathic scrotal edema (AISE) is a less known differential diagnosis of acute scrotum. In this study we aimed to describe prevalence and clinical management of children and adolescents with AISE treated in our clinic.319 patients at the age of 0 to 17 years with the diagnosis of acute scrotum treated in the clinic of pediatric urology Regensburg between 01/2013 and 12/2017 were included.Retrospective charts analysis.234/319 patients were treated as outpatients and 85/319 (27%) as inpatients. Diagnosis of AISE was made in 23/319 (7.2%) individuals. All of them were managed as outpatients and none received surgical exploration. Further diagnoses of outpatients: epididymitis (87/234; 37%); appendix testes torsion (42/234; 18%); testicular torsion (5/234; 2%); testicular trauma (10/234; 4%); hydrocele (9/234; 4%); nonspecific testicular pain (58/234; 25%). Diagnoses of inpatients: testicular torsion (58/85; 68%); appendix testes torsion (17/85; 20%); epididymitis (8/85; 9%); testicular trauma (1/85; 1%); tumor (1/85; 1%).In the differential diagnosis of acute scrotum the typical clinical presentation and the characteristic (Doppler) ultrasound findings allow the reliable diagnosis of AISE. Correct and prompt AISE diagnosis helps to avoid unnecessary hospitalizations, surgeries and medications.Pediatricians should be familiar with AISE as a differential diagnosis of acute scrotum.

Published
2020

9. Kulturtransfer in der frühen Neuzeit : Die Vorworte der Lyoner Drucke des 16. Jahrhunderts

Author

Sabine Vogel and Sabine Vogel

Subjects
Publishers and publishing--History.--France --, Books and reading--History.--France--Lyon, Humanism--History.--France--Lyon
Abstract

Die Rezeption antiken Gedankenguts ist bislang in wissenschaftsgeschichtlichen Untersuchungen einzelner Disziplinen behandelt worden. Sabine Vogel faßt unter der übergreifenden Fragestellung des Kulturtransfers die Einzelentwicklungen zusammen und zeigt Parallelen der wissenschaftlichen Methoden in den unterschiedlichen Disziplinen. Den Schwerpunkt ihrer Untersuchung bildet die Renaissance als Vermittlungsprozeß, innerhalb dessen die Vorkenntnisse und Absichten der Rezipienten Auswirkungen auf das jeweilige Bild der Antike hatten. Sie zeigt, daß sich dieses selbst innerhalb der res publica literarum unterschied. Zwar stimmten die humanistischen Gelehrten des 16. Jahrhunderts in der Ansicht überein, daß sich Bildung, Tugend und Eloquenz zu den studia humanitatis verbinden. Je nachdem, ob ein Gelehrter aus Deutschland, Italien oder Frankreich stammte, stellte er jedoch einen der drei Aspekte in den Vordergrund. Anhand einer Stichprobe aus der Lyoner Buchproduktion arbeitet Sabine Vogel heraus, welche Aspekte des humanistischen Gedankenguts und des antiken Erbes die Lyoner Verleger ihrerseits ihren Kunden in Editionen, Kompilationen, Schul- und Fachbüchern anboten. Dabei zeigt sich, daß es jenseits der professionellen Gelehrten ein französisches Lesepublikum mit einem eigenen intellektuellen Profil gab. Diese Leserschicht war derart etabliert, daß sie eine eigene Bezeichnung hatte: bons esprits. Für dieses Publikum brachten die Lyoner Verleger Kompendien in französischer Sprache heraus, welche eine sehr reduzierte Form humanistischer Gelehrsamkeit enthielten, die um mittelalterliche und zeitgenössische Erkenntnisse ergänzt wurde.

Published
2020

10. Tuning-in

Author

Sabine Vogel

Subjects
Music
Published
2015

11. Prolyl Hydroxylase Domain (PHD) 2 Affects Cell Migration and F-actin Formation via RhoA/Rho-associated Kinase-dependent Cofilin Phosphorylation

Author

Sinja Le-Huu, Sabine Vogel, Melanie von Ahlen, Gieri Camenisch, D. M. Katschinski, Katja Farhat, Anke Zieseniss, Cordula R. Malz, Moritz Schnelle, and Marieke Wottawa

Subjects
RHOA, Polymers, Procollagen-Proline Dioxygenase, macromolecular substances, Biology, Cell morphology, Models, Biological, Biochemistry, Hypoxia-Inducible Factor-Proline Dioxygenases, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Humans, Protein Isoforms, Phosphorylation, 10. No inequality, Molecular Biology, Cytoskeleton, Actin, 030304 developmental biology, rho-Associated Kinases, 0303 health sciences, Gene knockdown, Cell migration, Cell Biology, Cofilin, Molecular biology, Actins, Protein Structure, Tertiary, Cell biology, Actin Depolymerizing Factors, 030220 oncology & carcinogenesis, biology.protein, Signal transduction, rhoA GTP-Binding Protein, HeLa Cells, Protein Binding
Abstract

Cells are responding to hypoxia via prolyl-4-hydroxylase domain (PHD) enzymes, which are responsible for oxygen-dependent hydroxylation of the hypoxia-inducible factor (HIF)-1α subunit. To gain further insight into PHD function, we generated knockdown cell models for the PHD2 isoform, which is the main isoform regulating HIF-1α hydroxylation and thus stability in normoxia. Induction of a PHD2 knockdown in tetracycline-inducible HeLa PHD2 knockdown cells resulted in increased F-actin formation as detected by phalloidin staining. A similar effect could be observed in the stably transfected PHD2 knockdown cell clones 1B6 and 3B7. F-actin is at least in part responsible for shaping cell morphology as well as regulating cell migration. Cell migration was impaired significantly as a consequence of PHD2 knockdown in a scratch assay. Mechanistically, PHD2 knockdown resulted in activation of the RhoA (Ras homolog gene family member A)/Rho-associated kinase pathway with subsequent phosphorylation of cofilin. Because cofilin phosphorylation impairs its actin-severing function, this may explain the F-actin phenotype, thereby providing a functional link between PHD2-dependent signaling and cell motility.

Published
2010

12. Increased chemoresistance induced by inhibition of HIF-prolyl-hydroxylase domain enzymes

Author

Yohannes Hagos, Dörthe M. Katschinski, Sabine Vogel, Sinja Le-Huu, Malte Kleinschmidt, and Nils Brökers

Subjects
Cancer Research, Procollagen-Proline Dioxygenase, Antineoplastic Agents, ATP-binding cassette transporter, Biology, Carboplatin, HeLa, Mice, 03 medical and health sciences, 0302 clinical medicine, Gene expression, medicine, Animals, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, Etoposide, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Gene knockdown, General Medicine, Hypoxia-Inducible Factor 1, alpha Subunit, biology.organism_classification, Amino Acids, Dicarboxylic, Cell biology, Enzyme, Oncology, chemistry, Biochemistry, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Efflux, Signal transduction, HeLa Cells, medicine.drug
Abstract

The hypoxia-inducible factor (HIF) is the master regulator for oxygen-dependent gene expression. The HIF signal transduction pathway can be manipulated by inhibiting the activity of the HIFalpha-regulating prolyl-4-hydroxylase domain (PHD) enzymes. The consequence of inhibiting the PHD activity for chemoresistance was studied. Inhibiting the PHD activity with the 2-oxoglutarate analog dimethyloxaloylglycine (DMOG) results in increased chemoresistance towards etoposide but not carboplatin in HeLa cells. Evidence for an etoposide-specific resistance, which develops as a consequence of inhibiting the PHD activity, was further supported in a tetracycline-inducible PHD2 knockdown HeLa cell model. The etoposide-resistance was mediated by HIF-1alpha as shown in mouse embryonic fibroblast HIF-1alpha(+/+) and HIF-1alpha(-/-) cells. Decreased cellular cytotoxicity after etoposide treatment inversely correlated with a dimethyloxaloylglycine (DMOG)-inducible, HIF-1alpha-dependent enhanced MDR-1 expression and efflux activity as determined by RT-PCR, immunoblots, and with the fluorescent dye DiOC2. Taken together, our data indicate that PHD inhibitors might increase chemoresistance of tumor cells in a HIF-1-dependent manner.

Published
2010

13. Cor triatriatum sinister in an elderly patient—Findings in different imaging modalities and intraoperative correlation

Author

Dierk Werner, Andreas Lienemann, Hans-Hinrich Sievers, Martin Misfeld, Roger Eibel, Bernhard M. Graf, and Sabine Vogel

Subjects
Surgical results, medicine.medical_specialty, business.industry, Combined use, medicine.disease, Surgery, Imaging modalities, Cor triatriatum sinister, Contrast echocardiography, Cor triatriatum, medicine, Radiology, Nuclear Medicine and imaging, Radiology, Presentation (obstetrics), business, Elderly patient
Abstract

Cor triatriatum sinister is a rare congenital anomaly accounting for 0.1% of all congenital cardiac malformations. An incomplete incorporation of the common pulmonary vein into the left atrium is considered to be the cause of the disease. Fewer than 250 cases have been reported in the literature [Alphonso N, Norgaard MA, Newcomb A, d’Udekem Y, Brizard CR, Cochrane A. Cor triatriatum: presentation, diagnosis and long-term surgical results. Ann Thorac Surg 2005;80:1666–71], approximately 50 cases in adults [Modi KA, Senthilkumar A, Kiel E, Reddy PC. Diagnosis and surgical correction of cor triatriatum in an adult: combined use of transesophageal and contrast echocardiography, and a review of literature. Echocardiography 2006;23:506–9]. Although rare, the malformation is important to recognize because it may be easily correctable with good long-term surgical results [1]. We present the most relevant images of a woman with a classical cor triatriatum and discuss the different imaging modalities (first table of this paper).

Published
2007

14. Cardiomyocyte-Specific Transgenic Expression of Prolyl-4-Hydroxylase Domain 3 Impairs the Myocardial Response to Ischemia

Author

Marion Hölscher, Aline Jatho, Dörthe M. Katschinski, Sabine Vogel, Amke R. Hesse, Sabine Krull, and Anke Zieseniss

Subjects
Cardiac function curve, medicine.medical_specialty, Physiology, Transgene, Heart Ventricles, PHD3, Ischemia, Myocardial Infarction, Procollagen-Proline Dioxygenase, Context (language use), Aorta, Thoracic, Mice, Transgenic, Biology, Hypoxia-inducible factor, lcsh:Physiology, lcsh:Biochemistry, Mice, Internal medicine, medicine, Basic Helix-Loop-Helix Transcription Factors, Animals, lcsh:QD415-436, Myocytes, Cardiac, Transgenes, Hypoxia, Ligation, Cardioprotection, lcsh:QP1-981, Myocardium, Heart, Anatomy, Hypoxia (medical), medicine.disease, Hypoxia-Inducible Factor 1, alpha Subunit, Endocrinology, Hypoxia-inducible factors, Gene Expression Regulation, medicine.symptom, Signal Transduction
Abstract

Aims: The prolyl-4-hydroxylase domain (PHD) enzymes are representing novel therapeutic targets for ischemic tissue protection. Whereas the consequences of a knock out of the PHDs have been analyzed in the context of cardioprotection, the implications of PHD overexpression is unknown so far. Methods and Results: We generated cardiomyocyte-specific PHD3transgenic mice (cPhd3tg). Resting cPhd3tg mice did not show constitutive accumulation of HIF-1α or HIF-2α or changes in HIF target gene expression in the heart. Cardiac function was followed up for 14 months in these mice and found to be unchanged. After challenging the cPhd3tg mice with ligation of the left anterior descending artery, HIF-1α/-2α accumulation in the left ventricles was blunted. This was associated with a significantly increased infarct size of the cPhd3tg compared to wild type mice. Conclusion: Whereas overexpression of PHD3 in the resting state does not significantly influence cardiac function, it is crucial for the cardiac response to ischemia by affecting HIFα accumulation in the ischemic tissue.

Published
2015

15. N 2 H x Coordination at the Tripod‐Cobalt Template CH 3 C(CH 2 PPh 2 ) 3 Co: the Transformation of η 2 ‐HNNMe 2 into η 1 ‐NNMe 2 Ligands

Author

Sabine Vogel, Gottfried Huttner, Annette Barth, Laszlo Zsolnai, and Volkmar Körner

Subjects
Inorganic Chemistry, Crystallography, Deprotonation, Chemistry, Inorganic chemistry, Tripod (photography), chemistry.chemical_element, Nitrogenase, Electron, Redox, Cobalt
Abstract

While η2-coordination of N2H4 and N2H3- to tripod-cobalt entities has been reported, stabilization of N2H2 in this system has not yet been achieved. It is observed that [tripodCo(η2-HNNMe2)]+ (3) is transformed into [tripodCo(η1-NNMe2)]+ (4) by reaction with LiN(TMS)2 as a base. The deprotonation of 3 is accompanied by a redox reaction, and the overall reaction corresponds to the transformation of 3 to 4 with the loss of an electron and a proton. The observed coupling of deprotonation and oxidation is just the reverse of the processes assumed to occur during nitrogen fixation. The results are established by the usual analytical and spectroscopic techniques as well as by X-ray analyses.

Published
1997

16. Hypoxia Modulates Fibroblastic Architecture, Adhesion and Migration: A Role for HIF-1α in Cofilin Regulation and Cytoplasmic Actin Distribution

Author

Anke Zieseniss, Pia Leisering, Susanne Lutz, Christina M. Wuertz, Melanie Vogler, Sabine Krull, Dörthe M. Katschinski, Sabine Vogel, Katja Farhat, and Batra, Surinder K.

Subjects
Cytoplasm, Anatomy and Physiology, Cell, lcsh:Medicine, Actin Filaments, Biochemistry, Mice, 0302 clinical medicine, Cell Movement, Cell polarity, Molecular Cell Biology, Morphogenesis, lcsh:Science, Cytoskeleton, Hypoxia, HIF-1α, Cytoplasmic Actin Distribution, 0303 health sciences, Multidisciplinary, Physics, Cell migration, Cofilin, Flow Cytometry, Oxygen Metabolism, Cellular Structures, Cell Hypoxia, Cell biology, Cell Motility, medicine.anatomical_structure, Actin Depolymerizing Factors, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Medicine, Research Article, Cell Physiology, Immunoblotting, Biophysics, Cell Migration, Biology, Fluorescence, 03 medical and health sciences, Cell Line, Tumor, medicine, Cell Adhesion, Animals, Cell adhesion, Actin, 030304 developmental biology, Cell Size, Analysis of Variance, lcsh:R, Proteins, Fibroblasts, Hypoxia-Inducible Factor 1, alpha Subunit, Actins, Cytoskeletal Proteins, Metabolism, lcsh:Q, Developmental Biology
Abstract

Cells can adapt to hypoxia by various mechanisms. Yet, hypoxia-induced effects on the cytoskeleton-based cell architecture and functions are largely unknown. Here we present a comprehensive analysis of the architecture and function of L929 fibroblasts under hypoxic conditions (1% O2). Cells cultivated in hypoxia showed striking morphological differences as compared to cells cultivated under normoxic conditions (20% O2). These changes include an enlargement of cell area and volume, increased numbers of focal contacts and loss of cell polarization. Furthermore the β- and γ-actin distribution is greatly altered. These hypoxic adjustments are associated with enhanced cell spreading and a decline of cell motility in wound closure and single cell motility assays. As the hypoxia-inducible factor-1α (HIF-1α) is stabilised in hypoxia and plays a pivotal role in the transcriptional response to changes in oxygen availability we used an shRNA-approach to examine the role of HIF-1α in cytoskeleton-related architecture and functions. We show that the observed increase in cell area, actin filament rearrangement, decrease of single cell migration in hypoxia and the maintenance of p-cofilin levels is dependent on HIF-1α stabilisation. peerReviewed

Published
2013

17. Reaktionen des Tripod‐Co‐Templats CH 3 C(CH 2 PPh 2 ) 3 Co(II) mit funktionalisierten Hydrazinen

Author

Gottfried Huttner, Volkmar Körner, Olaf Walter, Laszlo Zsolnai, and Sabine Vogel

Subjects
Stereochemistry, Ligand, Tripod (photography), chemistry.chemical_element, Redox, Medicinal chemistry, Inorganic Chemistry, Diethyl azodicarboxylate, Metal, chemistry.chemical_compound, chemistry, Oxidation state, visual_art, visual_art.visual_art_medium, Chelation, Cobalt
Abstract

The coordination behaviour of ligands having the same basic constitution RN=NC(=X)R′ (X O, NR″, S) in their tripod cobalt derivatives has been analyzed. The ligands themselves may be considered as neutral heterodiene compounds and are in this respect vinylogues to diazenes RNNRy′. Two- electron reduction of these neutral species results in dianionic heterosubstituted heteroolefins RN- -NC(X-)R′. Due to their redox ambiguity the oxidation state of the metal M in chelate complexes is not a priori evident. Compounds tripod [5: X, R′ O, Ph; 6; (X, R′) (py); 7: X, R′ S, NH2] are best described as containing low-spin Co(III) and dianionic ligands. Co(II) species are obtained with diethyl azodicarboxylate EtOOCNNCOOEt as the ligand. In the mononuclear compound, with only one nitrogen and one carbonyl oxygen of the ligand acting as donor groups, the neutral ligand is coordinated to give the high-spin cobalt(II) species tripod (8). In the dinuclear compound 9 with both of the nitrogen atoms and carbonyl groups involved in coordination the dianionic ligand bridges two high-spin cobalt(II) centers to give tripod (9) as a derivative with two fused five-membered chelate rings. In addition to the conventional analytical techniques X-ray structure analyses, cyclovoltametric measurements, magnetic susceptibility and ESR data are used to characterize the compounds.

Published
1996

18. Knockdown of prolyl-4-hydroxylase domain 2 inhibits tumor growth of human breast cancer MDA-MB-231 cells by affecting TGF-β1 processing

Author

Joanna Napp, Glen Kristiansen, Katja Farhat, Mattia R Bordoli, Pia Leisering, Frauke Alves, Sabine Vogel, Dörthe M. Katschinski, Marieke Wottawa, Amke R. Hesse, Melanie von Ahlen, Cordula R. Malz, Gieri Camenisch, Moritz Schnelle, University of Zurich, and Katschinski, D M

Subjects
Cancer Research, Procollagen-Proline Dioxygenase, 610 Medicine & health, Breast Neoplasms, Biology, 10052 Institute of Physiology, Hypoxia-Inducible Factor-Proline Dioxygenases, Transforming Growth Factor beta1, 03 medical and health sciences, Mice, 0302 clinical medicine, Gene expression, Gene Knockdown Techniques, Animals, Humans, 1306 Cancer Research, Furin, 030304 developmental biology, Regulation of gene expression, 0303 health sciences, Gene knockdown, Molecular biology, Xenograft Model Antitumor Assays, Tumor Burden, Gene Expression Regulation, Neoplastic, Disease Models, Animal, Oncology, Tumor progression, 030220 oncology & carcinogenesis, 10076 Center for Integrative Human Physiology, Cancer research, biology.protein, 570 Life sciences, biology, 2730 Oncology, Female, Osteopontin, Signal transduction, Transforming growth factor, Signal Transduction
Abstract

The prolyl-4-hydroxylase domain 1-3 (PHD1-3) enzymes are regulating the protein stability of the α-subunit of the hypoxia-inducible factor-1 (HIF-1), which mediates oxygen-dependent gene expression. PHD2 is the main isoform regulating HIF-1α hydroxylation and thus stability in normoxia. In human cancers, HIF-1α is overexpressed as a result of intratumoral hypoxia which in turn promotes tumor progression. The role of PHD2 for tumor progression is in contrast far from being thoroughly understood. Therefore, we established PHD2 knockdown clones of MDA-MB-231 breast cancer cells and analyzed their tumor-forming potential in a SCID mouse model. Tumor progression was significantly impaired in the PHD2 knockdown MDA-MB-231 cells, which could be partially rescued by re-establishing PHD2 expression. In a RNA profile screen, we identified the secreted phosphoprotein 1 (SPP1) as one target, which is differentially regulated as a consequence of the PHD2 knockdown. Knockdown of PHD2 drastically reduced the SPP1 expression in MDA-MB-231 cells. A correlation of SPP1 and PHD2 expression was additionally verified in 294 invasive breast cancer biopsies. In subsequent analyses, we identified that PHD2 alters the processing of transforming growth factor (TGF)-β1, which is highly involved in SPP1 expression. The altered processing capacity was associated with a dislocation of the pro-protein convertase furin. Thus, our data demonstrate that in MDA-MB-231 cells PHD2 might affect tumor-relevant TGF-β1 target gene expression by altering the TGF-β1 processing capacity.

Published
2012

19. Serum tests for colorectal cancer screening

Author

James Creeden, Douglas K. Rex, Frank Junker, and Sabine Vogel-Ziebolz

Subjects
Pharmacology, Oncology, medicine.medical_specialty, business.industry, Colorectal cancer, Medical laboratory, MEDLINE, General Medicine, medicine.disease, digestive system diseases, Patient acceptance, Causes of cancer, Pharmacotherapy, Colorectal cancer screening, Internal medicine, Genetics, Biomarkers, Tumor, Molecular Medicine, Medicine, Humans, business, Colorectal Neoplasms, Early Detection of Cancer, Blood drawing
Abstract

Colorectal cancer (CRC) persists as one of the most significant causes of cancer death worldwide. Recent progress in reducing cancer mortality can largely be attributed to the implementation of screening programs. However, screening programs have not realized their full potential for the reduction of CRC mortality, because of poor adherence rates among patients. Serum biomarker screening tests offer the potential for improved patient adherence to CRC screening programs. In this review, we assess the literature regarding serum biomarkers for use as CRC screening tests for colorectal cancer and adenomas. A systematic review was performed of Medline-indexed articles pertaining to serum biomarkers for CRC screening published within the past 4 years. In addition, we searched non-Medline sources for information pertaining to screening guidelines and practice patterns for CRC. We identified 51 articles from Medline pertaining to serum biomarkers as screening tests for CRC. Non-Medline sources yielded an additional 12 articles, for a total of 63 publications reviewed. We conclude that serum tests that involve simple blood draws during routine check-ups hold significant promise for improving patient acceptance and adherence to CRC screening.

Published
2011

20. Fünffach koordinierte Co(III)-Komplexe [Tripod-Cobalt-(ortho(X)(Y)C6H4)]+ mit ortho-phenylenverbrückten Chelatliganden [(XH)(YH)C6H4] (XH, YH = NH2, OH, SH) / Five-Coordinate Co(III) Complexes [Tripod-Cobalt-(ortho-(X)(Y)C6H4)]+ Containing ortho-Phenylene-Bridged Chelate Ligands [(XH)(YH)C6H4] (XH, YH = NH2, OH, SH)

Author

Laszlo Zsolnai, Gottfried Huttner, and Sabine Vogel

Subjects
chemistry, Phenylene, Tripod (photography), chemistry.chemical_element, Chelation, General Chemistry, Medicinal chemistry, Cobalt
Abstract

The ortho-phenylene compounds ortho-[(XH)(YH)C6H4] (XH, YH = NH2, SH, OH) react with Co(BF4)2•6H2O and Tripod (CH3C(CH2PPh2)3) to give the five-coordinate Co(III) complexes [Tripod-Cobalt-(ortho-(X)(Y)C6H4)]+ (X, Y = NH, O, S), 1-6. The structures of 1—6 have been characterized by X-ray analyses of appropriate salts. The compounds have further been characterized by IR, NMR, UV-VIS and cyclovoltammetric measurements. As a compound analogous to 1—6, but containing the saturated chelate ligand [(S)C2H4(S)]2- instead of the conjugated ortho-phenylene type ligands of 1-6, [Tripod-Cobalt-((S)C2H4(S))]+, 7, has been prepared and fully characterized. It is inferred that the coordination geometries of 1-7 do not strongly depend on conjugative interaction within the chelating ligands.

Published
1993

21. H2NNH- und H2NO- als η2-koordinierte Liganden in Tripod-Cobalt-Komplexen / H2NNH- and H2NO- as η2-Coordinated Ligands in Tripod Cobalt Complexes

Author

Gottfried Huttner, Christiane Emmerich, Laszlo Zsolnai, and Sabine Vogel

Subjects
Chemistry, Polymer chemistry, Tripod (photography), chemistry.chemical_element, General Chemistry, Cobalt
Abstract

The complex cation [tripod Co η2-(NH2O)]+, 2, (tripod = CH3C(CH2PPh2)3) containing an η2-coordinated NH2O−-ligand is an isoelectronic equivalent to the recently reported complex [tripod Co η2-(Ν2Η3)]+, 1, which contains side-on coordinated N2H3 − [1,4]. The structures of the two cations 1 and 2 are almost superimposable. The structural discrimination between the NH2- and O- parts of the η2-NH2O--ligand in 2 has been corroborated by the synthesis and X-ray analysis of the cations [tripod Co η2-(NMe2O)]+, 3, and [tripod Co Cl (NH2OMe)]+, 4. The hydroxylamido(1–) compound 2 upon treatment with air transforms into the nitrosyl compound [tripod Co (NO)], 5, the structure of which has also been determined.

Published
1993

22. Cpc1 mediates cross-pathway control independently of Mbf1 in Fusarium fujikuroi

Author

Bettina Tudzynski, Birgit Schönig, and Sabine Vogel

Subjects
Nitrogen, Molecular Sequence Data, Down-Regulation, Biology, Microbiology, Fungal Proteins, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, Fusarium, Glutamate-Ammonia Ligase, Glutamine synthetase, Gene Expression Regulation, Fungal, Two-Hybrid System Techniques, Genetics, Amino Acids, Cloning, Molecular, Secondary metabolism, Gene, Transcription factor, Amino acid synthesis, 030304 developmental biology, Oligonucleotide Array Sequence Analysis, chemistry.chemical_classification, 0303 health sciences, 030306 microbiology, Gene Expression Profiling, Genetic Complementation Test, Gibberellins, Amino acid, Up-Regulation, Metabolic pathway, Basic-Leucine Zipper Transcription Factors, Phenotype, chemistry, Biochemistry, Metabolic Networks and Pathways, Transcription Factors
Abstract

The deletion of glnA, encoding the glutamine synthetase (GS), had led to the down-regulation of genes involved in secondary metabolism and up-regulation of cpc1, the cross-pathway control transcription factor. In the present study, a Deltacpc1 mutant was created and used for transcriptional profiling by macroarray analysis. Most of the Cpc1 target genes were amino acid biosynthesis genes besides a homologue of the multi-protein bridging factor MBF1 that binds to the yeast Cpc1 homologue GCN4. We show that Deltambf1 mutants exhibit no Cpc1-related phenotype and that both proteins do not interact with each other in Fusarium fujikuroi. Moreover, results presented here suggest that Cpc1 is not responsible for the GS-dependent down-regulation of secondary metabolism and that its role is focused on the activation of amino acid biosynthesis in response to the amino acid status of the cell. Surprisingly, cross-pathway control is repressed by nitrogen limitation in an AreA-dependent manner.

Published
2009

23. Intelligent kommunizieren — emotional binden

Author

Sabine Vogel and Ulrich Prosch

Abstract

Es sind bewegte Zeiten fur Kreditinstitute, der Wettbewerb wird harter. Im Kampf um Privatkunden setzt sich immer mehr die Erkenntnis durch, dass Kundenansprache und Beratungsqualitat deutlich verbessert werden mussen — dass eine strategische Neuausrichtung der Vertriebswege erforderlich ist. In diesem Zusammenhang gewinnt die „gute alte“ Bankfiliale wieder an Bedeutung. Sie soll kunftig zum zentralen Ankerpunkt des Kunde-Bank-Dialogs werden und durch die Inszenierung spontaner Begegnungsanlasse den Aufbau einer emotionalen Beziehung zwischen Kunde und Bank aktiv gestalten.

Published
2008

25. L

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

26. Q

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

27. M

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

28. P

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

29. O

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

30. R

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

31. U

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

32. N

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

33. Z

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

34. T

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

35. S

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

36. X

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

37. V

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

38. Y

Author

Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow, and A. Kluge

Published
1999

39. A

Author

F. von Bruchhausen, S. Ebel, A. W. Frahm, E. Hackenthal, Margitta Albinus, Hassan-Fahmy Ali, Syed Laik Ali, Gudrun Amschler, Uwe Amschler, Erwin von Angerer, Peter Barth, Wolfgang Barthel, Kurt Bauer, Andrea Bauer, Jürgen Beckmann, Winfried Beil, Jürgen Beitz, Günther Bellmann, Thorsten Beyrich, Franz Bossle, Helmut Bräunlich, Matthias Bräutigam, Kerstin Brinkmann, Adalbert Brinz, Franz von Bruchhausen, Kay Brune, Axel Büge, Ulrich Bürger, Wolfram Christ, Klaus Daneck, Gerd Dannhardt, Helga Doering, Siegfried Ebel, Kurt Eger, Peter Emig, Thomas Erker, Bernhard Feil, Monika Fett, August Wilhelm Frahm, Margarete Frahm, Klaus-Jürgen Freundt, Wolfram Gaida, Detlef Geffken, Ulrich Geis, Klaus Geldsetzer, Ulrich Gessner, Erika Glusa, Berthold Göber, Margarete Goppelt-Strübe, Wilhelm Gössling, Eberhard Gottwald, Beate Grates, Annette Graul, Sibylle Greiner, Adolf Grisk, Michael Grosam, Jan Gustafsson, Hartmut Gustmann, Jürgen Haas, Axel Haberkorn, Eberhard Hackenthal, Annette Häfner, Boris Haluszczynski, Achim Harder, Susanne Hartmann, Heribert Häusler, Marcus Heidenreich, Gerhard Heinemeyer, Bernd Hempel, Monika Herboth, Klaus Herbrand, Sibylle Hoedt-Schmidt, Wolfgang Hoefke, Hermann Hoffmann, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Ulrike Holzgrabe, Anette Hornberger, Ute Hübner-Steiner, Martin Hug, Wolfgang Ibrom, Walter Janßen, Angela Jördens, Ilmar Jurna, Günther Kaiser, Dieter-Abbo Kalbhen, Petra Kisser, Christoph Klett, Stephanie Klett, Gerd Kobal, Johannes Koehler, Axel Kramer, Birgit Krammer, Gottfried Kreutz, Reinhard Kroker, Markus Kuhn, Norbert Kühn, Dorothea Landsiedel, Andreas Langner, Martina Laudszun, Jochen Lehmann, Marion Sylvia Lehner, Stefan Leiner, Hans Löwe, Johannes Mann, Detlef Manns, Wolfgang Matthiessen, Rainer Maue, Peter Maul, Andreas Maurer, Ralf Mayer, Wolfgang Meindl, Werner Meise, Klaus Menges, Paul Messinger, Hans-Jürgen Mest, Frank Peter Meyer, J. Mollière, Rudolf Morgenstern, Wolfgang Morick, Joachim Mössner, Alfred Müller, Walter E. Müller, Klaus Müller, Christa Müller, Daniel Müller, Michael Neugebauer, Ottmar Neugebauer, Peter Nickel, Peter Nuhn, Bernd Nürnberg, Joachim Oertel, Michael Oettel, Tilmann Ott, Thomas Otzen, Hartmut Oßwald, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Siegfried Pfeifer, Klaus Pietrzik, Kathrin Pöllath, Olaf Queckenberg, Bernd Raffelsberger, Eberhard Reimann, Jörg Remien, Markus Reuß, Andreas Reymann, Joachim Richter, Peter H. Richter, Hubert Richter, Klaus Rittinghaus, Hans Rommelspacher, Gerhard Rücker, Gerhard Schaefer, Klaus Schaefer, Jutta Schcerer, Helmut Schlager, Hildegard Schleinitz, Wolfgang Schlichter, Gerhard Schmidt, Wolfgang Schmutzler, Johannes Schräder, Thomas Schulz-Schalge, Harald Schütz, Helmut Schwilden, Gisela Skopp, Ulrich Speck, Marcus Spohn, Ralf Stahlmann, Johannes-Peter Stasch, E. Staubli, Jürgen Steinmeyer, Karl-Heinz Stiefvater, Michael Streek, Günther Strippel, Karl-Heinz Surborg, Ulf Sürig, Istvan Szelenyi, Alfred Thomas, Herbert Trampisch, Reinhard Troschütz, Bernard Unterhalt, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Sven Völkl, Heinz Walther, Horst Weber, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Burkhard Wichert, Hilke Winterhoff, Peter Witte, and Monika Wolff

Published
1993

40. B

Author

F. von Bruchhausen, S. Ebel, A. W. Frahm, E. Hackenthal, Margitta Albinus, Hassan-Fahmy Ali, Syed Laik Ali, Gudrun Amschler, Uwe Amschler, Erwin von Angerer, Peter Barth, Wolfgang Barthel, Kurt Bauer, Andrea Bauer, Jürgen Beckmann, Winfried Beil, Jürgen Beitz, Günther Bellmann, Thorsten Beyrich, Franz Bossle, Helmut Bräunlich, Matthias Bräutigam, Kerstin Brinkmann, Adalbert Brinz, Franz von Bruchhausen, Kay Brune, Axel Büge, Ulrich Bürger, Wolfram Christ, Klaus Daneck, Gerd Dannhardt, Helga Doering, Siegfried Ebel, Kurt Eger, Peter Emig, Thomas Erker, Bernhard Feil, Monika Fett, August Wilhelm Frahm, Margarete Frahm, Klaus-Jürgen Freundt, Wolfram Gaida, Detlef Geffken, Ulrich Geis, Klaus Geldsetzer, Ulrich Gessner, Erika Glusa, Berthold Göber, Margarete Goppelt-Strübe, Wilhelm Gössling, Eberhard Gottwald, Beate Grates, Annette Graul, Sibylle Greiner, Adolf Grisk, Michael Grosam, Jan Gustafsson, Hartmut Gustmann, Jürgen Haas, Axel Haberkorn, Eberhard Hackenthal, Annette Häfner, Boris Haluszczynski, Achim Harder, Susanne Hartmann, Heribert Häusler, Marcus Heidenreich, Gerhard Heinemeyer, Bernd Hempel, Monika Herboth, Klaus Herbrand, Sibylle Hoedt-Schmidt, Wolfgang Hoefke, Hermann Hoffmann, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Ulrike Holzgrabe, Anette Hornberger, Ute Hübner-Steiner, Martin Hug, Wolfgang Ibrom, Walter Janßen, Angela Jördens, Ilmar Jurna, Günther Kaiser, Dieter-Abbo Kalbhen, Petra Kisser, Christoph Klett, Stephanie Klett, Gerd Kobal, Johannes Koehler, Axel Kramer, Birgit Krammer, Gottfried Kreutz, Reinhard Kroker, Markus Kuhn, Norbert Kühn, Dorothea Landsiedel, Andreas Langner, Martina Laudszun, Jochen Lehmann, Marion Sylvia Lehner, Stefan Leiner, Hans Löwe, Johannes Mann, Detlef Manns, Wolfgang Matthiessen, Rainer Maue, Peter Maul, Andreas Maurer, Ralf Mayer, Wolfgang Meindl, Werner Meise, Klaus Menges, Paul Messinger, Hans-Jürgen Mest, Frank Peter Meyer, J. Mollière, Rudolf Morgenstern, Wolfgang Morick, Joachim Mössner, Alfred Müller, Walter E. Müller, Klaus Müller, Christa Müller, Daniel Müller, Michael Neugebauer, Ottmar Neugebauer, Peter Nickel, Peter Nuhn, Bernd Nürnberg, Joachim Oertel, Michael Oettel, Tilmann Ott, Thomas Otzen, Hartmut Oßwald, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Siegfried Pfeifer, Klaus Pietrzik, Kathrin Pöllath, Olaf Queckenberg, Bernd Raffelsberger, Eberhard Reimann, Jörg Remien, Markus Reuß, Andreas Reymann, Joachim Richter, Peter H. Richter, Hubert Richter, Klaus Rittinghaus, Hans Rommelspacher, Gerhard Rücker, Gerhard Schaefer, Klaus Schaefer, Jutta Schcerer, Helmut Schlager, Hildegard Schleinitz, Wolfgang Schlichter, Gerhard Schmidt, Wolfgang Schmutzler, Johannes Schräder, Thomas Schulz-Schalge, Harald Schütz, Helmut Schwilden, Gisela Skopp, Ulrich Speck, Marcus Spohn, Ralf Stahlmann, Johannes-Peter Stasch, E. Staubli, Jürgen Steinmeyer, Karl-Heinz Stiefvater, Michael Streek, Günther Strippel, Karl-Heinz Surborg, Ulf Sürig, Istvan Szelenyi, Alfred Thomas, Herbert Trampisch, Reinhard Troschütz, Bernard Unterhalt, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Sven Völkl, Heinz Walther, Horst Weber, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Burkhard Wichert, Hilke Winterhoff, Peter Witte, and Monika Wolff

Published
1993

41. C

Author

F. von Bruchhausen, S. Ebel, A. W. Frahm, E. Hackenthal, Margitta Albinus, Hassan-Fahmy Ali, Syed Laik Ali, Gudrun Amschler, Uwe Amschler, Erwin von Angerer, Peter Barth, Wolfgang Barthel, Kurt Bauer, Andrea Bauer, Jürgen Beckmann, Winfried Beil, Jürgen Beitz, Günther Bellmann, Thorsten Beyrich, Franz Bossle, Helmut Bräunlich, Matthias Bräutigam, Kerstin Brinkmann, Adalbert Brinz, Franz von Bruchhausen, Kay Brune, Axel Büge, Ulrich Bürger, Wolfram Christ, Klaus Daneck, Gerd Dannhardt, Helga Doering, Siegfried Ebel, Kurt Eger, Peter Emig, Thomas Erker, Bernhard Feil, Monika Fett, August Wilhelm Frahm, Margarete Frahm, Klaus-Jürgen Freundt, Wolfram Gaida, Detlef Geffken, Ulrich Geis, Klaus Geldsetzer, Ulrich Gessner, Erika Glusa, Berthold Göber, Margarete Goppelt-Strübe, Wilhelm Gössling, Eberhard Gottwald, Beate Grates, Annette Graul, Sibylle Greiner, Adolf Grisk, Michael Grosam, Jan Gustafsson, Hartmut Gustmann, Jürgen Haas, Axel Haberkorn, Eberhard Hackenthal, Annette Häfner, Boris Haluszczynski, Achim Harder, Susanne Hartmann, Heribert Häusler, Marcus Heidenreich, Gerhard Heinemeyer, Bernd Hempel, Monika Herboth, Klaus Herbrand, Sibylle Hoedt-Schmidt, Wolfgang Hoefke, Hermann Hoffmann, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Ulrike Holzgrabe, Anette Hornberger, Ute Hübner-Steiner, Martin Hug, Wolfgang Ibrom, Walter Janßen, Angela Jördens, Ilmar Jurna, Günther Kaiser, Dieter-Abbo Kalbhen, Petra Kisser, Christoph Klett, Stephanie Klett, Gerd Kobal, Johannes Koehler, Axel Kramer, Birgit Krammer, Gottfried Kreutz, Reinhard Kroker, Markus Kuhn, Norbert Kühn, Dorothea Landsiedel, Andreas Langner, Martina Laudszun, Jochen Lehmann, Marion Sylvia Lehner, Stefan Leiner, Hans Löwe, Johannes Mann, Detlef Manns, Wolfgang Matthiessen, Rainer Maue, Peter Maul, Andreas Maurer, Ralf Mayer, Wolfgang Meindl, Werner Meise, Klaus Menges, Paul Messinger, Hans-Jürgen Mest, Frank Peter Meyer, J. Mollière, Rudolf Morgenstern, Wolfgang Morick, Joachim Mössner, Alfred Müller, Walter E. Müller, Klaus Müller, Christa Müller, Daniel Müller, Michael Neugebauer, Ottmar Neugebauer, Peter Nickel, Peter Nuhn, Bernd Nürnberg, Joachim Oertel, Michael Oettel, Tilmann Ott, Thomas Otzen, Hartmut Oßwald, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Siegfried Pfeifer, Klaus Pietrzik, Kathrin Pöllath, Olaf Queckenberg, Bernd Raffelsberger, Eberhard Reimann, Jörg Remien, Markus Reuß, Andreas Reymann, Joachim Richter, Peter H. Richter, Hubert Richter, Klaus Rittinghaus, Hans Rommelspacher, Gerhard Rücker, Gerhard Schaefer, Klaus Schaefer, Jutta Schcerer, Helmut Schlager, Hildegard Schleinitz, Wolfgang Schlichter, Gerhard Schmidt, Wolfgang Schmutzler, Johannes Schräder, Thomas Schulz-Schalge, Harald Schütz, Helmut Schwilden, Gisela Skopp, Ulrich Speck, Marcus Spohn, Ralf Stahlmann, Johannes-Peter Stasch, E. Staubli, Jürgen Steinmeyer, Karl-Heinz Stiefvater, Michael Streek, Günther Strippel, Karl-Heinz Surborg, Ulf Sürig, Istvan Szelenyi, Alfred Thomas, Herbert Trampisch, Reinhard Troschütz, Bernard Unterhalt, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Sven Völkl, Heinz Walther, Horst Weber, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Burkhard Wichert, Hilke Winterhoff, Peter Witte, and Monika Wolff

Published
1993

42. Similarity in Temporal Movement Patterns in Laying Hens Increases with Time and Social Association

Author

Yamenah Gómez, John Berezowski, Yandy Abreu Jorge, Sabine G. Gebhardt-Henrich, Sabine Vögeli, Ariane Stratmann, Michael Jeffrey Toscano, and Bernhard Voelkl

Subjects
social network, phenotype variation, individuality, movement pattern, behavioural plasticity, Veterinary medicine, SF600-1100, Zoology, QL1-991
Abstract

We explored the relationship between social associations and individual activity patterns in domestic hens. Out of 1420 laying hens, 421 hens were equipped with RFID tags attached to RFID-specific leg bands (leg bands from Company Roxan, Selkirk, Scotland) to continuously track their change in location across four different areas (one indoor and three outdoor areas). Using a combination of social network analysis for quantifying social relationships and dynamic time warping for characterizing the movement patterns of hens, we found that hens were consistent in their individual variation in temporal activity and maintained stable social relationships in terms of preferred association partners. In addition to being consistent, social associations correlated with movement patterns and this correlation strengthened over the period of observation, suggesting that the animals aligned their activity patterns with those of their social affiliates. These results demonstrate the importance of social relationships when considering the expression of individual behaviour. Notably, differences in temporal patterns emerge despite rather homogeneous rearing conditions, same environment, and low genetic diversity. Thus, while variation in behavioural phenotypes can be observed across isolated individuals, this study shows that the social environment within a group can shape and enhance variation in general movement patterns of individual animals.

Published
2022
Full Text
View/download PDF

45. Assignment of conserved amino acid residues to the ATP site in the protein kinase domain of the receptor for epidermal growth factor

Author

Jürgen Hoppe, Wolfgang Freist, and Sabine Vogel

Subjects
chemistry.chemical_classification, GTP', Protein Conformation, Kinase, Cell Membrane, Receptors, Cell Surface, Protein-Tyrosine Kinases, Biology, Biochemistry, Cell Line, ErbB Receptors, Kinetics, Structure-Activity Relationship, chemistry.chemical_compound, Adenosine Triphosphate, Enzyme, Protein structure, chemistry, Epidermal growth factor, Ribose, Animals, Amino Acid Sequence, Adenosine triphosphate, Peptide sequence
Abstract

The ATP substrate site in the epidermal growth factor (EGF) receptor was mapped by using a series of 26 ATP derivatives with modifications at the base, ribose or triphosphate moiety. Ki values for these derivatives were determined by competition with [gamma-32P]ATP. The enzyme seems to interact specifically with the beta-phosphate in an ion-pair bond with the N-6 amino group at the adenine in a hydrogen bond. With ribosyl-2-aminopurine triphosphate and GTP, the enzyme most likely recognizes the 2-amino group in a hydrogen bond. This high specificity for ATP and GTP is unique for the ATP site in the EGF receptor among all investigated protein kinases. The available data on the interaction between ATP derivatives and protein kinases were used to assign conserved amino acid residues found in diverse protein kinases to the ATP site in this type of enzyme.

Published
1986

46. Polyamines stimulate the phosphorylation of phosphatidylinositol in membranes from A 431 cells

Author

Jürgen Hoppe and Sabine Vogel

Subjects
Epidermal Growth Factor, Kinase, Cell Membrane, Phosphotransferases, Phosphatidylinositol Phosphates, Biology, Phosphatidylinositols, Biochemistry, Cell Line, Substrate Specificity, Cell biology, Pleckstrin homology domain, Spermidine, chemistry.chemical_compound, Adenosine Triphosphate, chemistry, Polyamines, Phosphorylation, Phosphatidylinositol, Protein kinase A, 1-Phosphatidylinositol 4-Kinase, Phosphoinositide-dependent kinase-1
Abstract

The phosphorylation of phosphatidylinositol in plasma membranes from A431 cells was investigated using [γ-32P]ATP as the substrate. Phosphatidylinositol 4-phosphate was found to be the major product after an incubation time of 5–10 min. Little, if any, phosphatidylinositol 4,5-bisphosphate was found under these conditions. Epidermal growth factor (EGF) had no effect on the formation of phosphatidylinositol 4-phosphate or phosphatidylinositol 4,5-bisphosphate. On the other hand, the polyamines spermidine and spermine stimulated the phosphatidylinositol kinase activity about eightfold yielding almost exclusively phosphatidylinositol 4-phosphate as the reaction product. Half-maximum stimulation by spermidine occurred under near physiological conditions (1.5 mM). Furthermore various proteins and amino acid polymers containing clustered basic amino acid residues (e. g. histones and polylysine) stimulated the formation of phosphatidylinositol 4-phosphate to a similar extent. Half-maximal concentrations for the activation were considerably lower ranging from 1.5 μM to 80 μM. The ATP specificity of the phosphatidylinositol kinase(s) was investigated with a small set of selected ATP derivatives. In the presence of spermidine the specificity changed significantly indicating that (a) spermidine acts on a kinase and not on a phosphatase, (b) this activity is distinct from the EGF-receptor protein kinase activity. The results do not suggest an involvement of the EGF receptor in the growth-factor-dependent formation of phosphatidylinositol phosphates. It is proposed that the phosphorylation of phosphatidylinositol by polyamines might be a mechanism to replenish the pool of inositolphospholipids.

Published
1986

Catalog

Books, media, physical & digital resources
See catalog results