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Background: Cochlear synaptopathy is a disorder where auditory perceptual impairments, such as speech perception in noise and tinnitus, may not be accurately reflected by audiometric thresholds, even if the audiogram appears normal. It is proposed that the connections between hair cells and the auditory nerve are more susceptible to sound and aging damage than the cochlea's hair cells. Cochlear synaptopathy can be present in ears with normal audiograms and undamaged hair cells, leading to hidden hearing loss. This study aims to construct electrophysiological and behavioral auditory parameters associated with persons exposed to loudness and having normal audiograms and auditory complaints to identify hidden hearing loss. Results: A case–control study was done with forty participants with a documented history of exposure to loud sounds and various auditory complaints, compared to a control group of forty persons who had all been confirmed to have normal audiograms. The chosen behavioral core tests comprised the speech intelligibility in noise test (SPIN), gaps detection in noise (GIN test), and pitch pattern sequence test (PPS). The electrophysiological measures utilized in the study were the auditory brainstem response test (ABR) and electrocochleography (ECochG). The SPIN, PPS, and GIN test results demonstrated statistically significant disparities between the control and case groups. The amplitude ratio of wave I to wave V in ABR and the ratio of EcochG AP to SP demonstrated a statistically significant variance between the two groups. The SPIN test exhibited the highest AUC, signifying its superior diagnostic capability in identifying hidden hearing loss. Conclusion: The present study has shown that the SPIN, as a behavioral test, and the EcochG AP amplitude measure, as an electrophysiological test, provide the greatest auditory diagnostic capability for identifying cochlear synaptopathy. Wave I amplitude in the auditory brainstem response (ABR) and the SP/AP ratio in electrocochleography (EcochG) are promising non-behavioral measures of cochlear synaptopathy or hidden hearing loss. [ABSTRACT FROM AUTHOR]

Background: The use of platelet-rich plasma (PRP) in orthopaedics continues to increase. One common use of PRP is as an adjunct in rotator cuff repair surgery. Multiple systematic reviews and meta-analyses have summarized the data on PRP use in rotator cuff repair surgery. However, systematic reviews and meta-analyses are subject to spin bias, where authors' interpretations of results influence readers' interpretations. Purpose: To evaluate spin in the abstracts of systematic reviews and meta-analyses of PRP with rotator cuff repair surgery. Study Design: Systematic review; Level of evidence, 3. Methods: A PubMed and Embase search was conducted using the terms rotator cuff repair and PRP and systematic review or meta-analysis. After review of 74 initial studies, 25 studies met the inclusion criteria. Study characteristics were documented, and each study was evaluated for the 15 most common forms of spin and using the AMSTAR 2 (A Measurement Tool to Assess Systematic Reviews, Version 2) rating system. Correlations between spin types and study characteristics were evaluated using binary logistic regression for continuous independent variables and a chi-square test or Fisher exact test for categorical variables. Results: At least 1 form of spin was found in 56% (14/25) of the included studies. In regard to the 3 different categories of spin, a form of misleading interpretation was found in 56% (14/25) of the studies. A form of misleading reporting was found in 48% (12/25) of the studies. A form of inappropriate extrapolation was found in 16% (4/25) of the studies. A significant association was found between misleading interpretation and publication year (odds ratio [OR], 1.41 per year increase in publication; 95% CI, 1.04-1.92; P =.029) and misleading reporting and publication year (OR, 1.41 per year increase in publication; 95% CI, 1.02-1.95; P =.037). An association was found between inappropriate extrapolation and journal impact factor (OR, 0.21 per unit increase in impact factor; 95% CI, 0.044-0.99; P =.048). Conclusion: A significant amount of spin was found in the abstracts of systematic reviews and meta-analyses of PRP use in rotator cuff repair surgery. Given the increasing use of PRP by clinicians and interest among patients, spin found in these studies may have a significant effect on clinical practice. [ABSTRACT FROM AUTHOR]

Let X be a compact and connected Riemann surface of genus g ≥ 2. In this paper, moduli spaces of Higgs bundles over X with structure group SL(n, ℂ), for n ≥ 3, and Spin(2n, ℂ), for n ≥ 4, are considered. In the case of structure group SL(n, ℂ), two involutions of the Higgs bundle moduli space are defined and an alternative proof is given to show, using specific properties of the structure group, that the stable fixed points can be described as certain Higgs pairs with structure group SO(n, ℂ) or Sp(n, ℂ). Moreover, the notions of stability, semistability, and polystability of the obtained Higgs pairs are established. Also, two involutions of the moduli space of Higgs bundles with structure group Spin(2n, ℂ) are defined for n ≥ 4 analogously and it is shown, also using specific properties of the group, that their stable fixed points can be described as certain Higgs pairs whose structure group is of the form Spin(2r + 1, ℂ) × Spin(2n − 2r − 1, ℂ) for some 0 ≤ r ≤ n − 1. [ABSTRACT FROM AUTHOR]

Background: Poor reporting quality and spin in randomized controlled trial (RCT) abstracts can lead to misinterpretation and distorted interpretation of results. Objectives: This methodological study aimed to assess the reporting quality and spin among RCT abstracts on splint therapy for temporomandibular disorders (TMD) and explore the association between spin and potentially related factors. Methods: The authors searched PubMed for RCTs on splint therapy for TMD. The reporting quality of each abstract was assessed using the original 16‐item CONSORT for abstracts checklist. The authors evaluated the presence and characteristics of spin only in abstracts with nonsignificant primary outcomes according to pre‐determined spin strategies. Logistic regression analyses were performed to identify factors associated with the presence of spin. Results: A total of 148 abstracts were included in the reporting quality evaluation. The mean overall CONSORT score (OCS) was 5.86 (score range: 0–16). Only interventions, objectives and conclusions were adequately reported. Of the 61 RCT abstracts included for spin analysis, spin was identified in 38 abstracts (62.3%), among which 32 abstracts (52.3%) had spin in the Results section and 21 (34.4%) had spin in the Conclusions section. A significantly lower presence of spin was found in studies with exact p‐value reporting (OR: 0.170; 95% CI: 0.032–0.887; p =.036) and a two‐arm comparison design (OR: 11.777; 95% CI: 2.171–63.877; p =.004). Conclusions: The reporting quality of RCT abstracts on splint therapy for TMD is suboptimal and the prevalence of spin is high. More awareness and joint efforts are needed to improve reporting quality and minimize spin. [ABSTRACT FROM AUTHOR]

The interaction between electron spin and oxygen molecules in non‐platinum catalysts, particularly carbon catalysts, significantly influences the catalytic performance of the oxygen reduction reaction (ORR). A promising approach to developing high‐performance catalysts involves introducing five‐membered ring structures with spin into graphitic carbons. In this study, we present the successful synthesis of cage‐like cubic carbon catalysts enriched with pentagon structures using pentagon ring‐containing C60 and a NaCl template. The number of pentagons contained in the structure was increased by doping with nitrogen and annealing, and the number of electron spins also increased, thereby improving catalytic activity. The prepared catalyst exhibits remarkable activity in ORR under acidic electrolytes. Furthermore, we elucidate the correlation between the pentagon structure, the number of spin, and catalytic activity, demonstrating that enhanced activity is contingent upon the presence of spin. Density functional theory (DFT) calculations support the role of spin in improving activity. The concept of spin and the introduction of pentagon structures provide new design principles for carbon catalysts. [ABSTRACT FROM AUTHOR]

Comprehensive Summary: The stability of organic radicals in ambient condition is important for their practical application. During the development of organic radical chemistry, the electron‐withdrawing and steric hindrance groups are usually introduced to improve the stability of radicals via reducing the reactivity of radicals with oxygen in air. Herein, the electron‐withdrawing carbonyl groups are introduced to construct a planar aromatic oxalic acid radical (IDF‐O8) with two‐dimensional electron spin pan structure. Interestingly, IDF‐O8 exhibited a low optical bandgap of 0.91 eV in film, however, the multiple quinone resonance structures between electron‐withdrawing ketone and phenol radicals contribute to the high stability of open‐shell radical IDF‐O8 without protection of large steric hindrance groups. Under the irradiation of 808 nm (1.2 W·cm–2), IDF‐O8 reaches 147 °C in powder state. This work provides an efficient synthesis route for the open‐shell electron spin pan system, which is different from the famous fullerene, carbon nanotube and graphene. The electron spin pan can be extended to spin tube or spin sphere system based on the design strategy of aromatic inorganic acid radicals in future. [ABSTRACT FROM AUTHOR]

Objective: To demonstrate the noninferiority of the novel hemostatic agent, Hemofence (BMI Korea Co., Ltd., thrombin cross-linked sodium hyaluronate gel matrix) compared to the established agent, Floseal Hemostatic Matrix (Baxter, thrombin-gelatin matrix) in achieving hemostasis for spinal surgeries, with secondary objectives to assess additional efficacy and safety. Methods: This clinical trial was a multicenter, randomized, subject-blinded, active-controlled, parallel-group, phase 3 study. Investigational drugs were administered to the first and second bleeding sites of each participant (or only to the first site if a second site was absent), evaluating hemostasis success rate within 10 minutes and the time to achieve hemostasis. Subsequent visits were conducted for safety assessments. For noninferiority test, a 97.5% one-sided confidence interval (CI) was used; the test group was deemed noninferior if the lower limit exceeded -10%. Results: This trial showed a 97.10% success rate in the test group and 96.05% in the control group for primary efficacy. The 95% CI (-4.90% to 7.44%) confirmed the test drug's noninferiority. Time to hemostasis showed no significant difference between groups. All adverse events, adverse drug reactions, and serious adverse events were statistically similar between groups (p=1.000, p=0.243, and p=0.966, respectively). Conclusion: A novel hemostatic agent, Hemofence, demonstrated an efficacy and safety profile comparable to that of Floseal. [ABSTRACT FROM AUTHOR]

Magnetizing the surface states of topological insulators without damaging their topological features is a crucial step for realizing the quantum anomalous Hall (QAH) effect and remains a challenging task. The TI–ferromagnetic material interface system was constructed and studied by the density functional theory (DFT). A two-dimensional magnetic semiconductor CrWI6 has been proven to effectively magnetize topological surface states (TSSs) via the magnetic proximity effect. The non-trivial phase was identified in the Bi2Se3 (BS) films with six quantum layers (QL) within the CrWI6/BS/CrWI6 heterostructure. BS thin films exhibit the generation of spin splitting near the TSSs, and a band gap of approximately 2.9 meV is observed at the Γ in the Brillouin zone; by adjusting the interface distance of the heterostructure, we increased the non-trivial band gap to 7.9 meV, indicating that applying external pressure is conducive to realizing the QAH effect. Furthermore, the topological non-triviality of CrWI6/6QL-BS/CrWI6 is confirmed by the nonzero Chern number. This study furnishes a valuable guideline for the implementation of the QAH effect at elevated temperatures within heterostructures comprising two-dimensional (2D) magnetic monolayers (MLs) and topological insulators. [ABSTRACT FROM AUTHOR]

Abstract Background Cochlear synaptopathy is a disorder where auditory perceptual impairments, such as speech perception in noise and tinnitus, may not be accurately reflected by audiometric thresholds, even if the audiogram appears normal. It is proposed that the connections between hair cells and the auditory nerve are more susceptible to sound and aging damage than the cochlea’s hair cells. Cochlear synaptopathy can be present in ears with normal audiograms and undamaged hair cells, leading to hidden hearing loss. This study aims to construct electrophysiological and behavioral auditory parameters associated with persons exposed to loudness and having normal audiograms and auditory complaints to identify hidden hearing loss. Results A case–control study was done with forty participants with a documented history of exposure to loud sounds and various auditory complaints, compared to a control group of forty persons who had all been confirmed to have normal audiograms. The chosen behavioral core tests comprised the speech intelligibility in noise test (SPIN), gaps detection in noise (GIN test), and pitch pattern sequence test (PPS). The electrophysiological measures utilized in the study were the auditory brainstem response test (ABR) and electrocochleography (ECochG). The SPIN, PPS, and GIN test results demonstrated statistically significant disparities between the control and case groups. The amplitude ratio of wave I to wave V in ABR and the ratio of EcochG AP to SP demonstrated a statistically significant variance between the two groups. The SPIN test exhibited the highest AUC, signifying its superior diagnostic capability in identifying hidden hearing loss. Conclusion The present study has shown that the SPIN, as a behavioral test, and the EcochG AP amplitude measure, as an electrophysiological test, provide the greatest auditory diagnostic capability for identifying cochlear synaptopathy. Wave I amplitude in the auditory brainstem response (ABR) and the SP/AP ratio in electrocochleography (EcochG) are promising non-behavioral measures of cochlear synaptopathy or hidden hearing loss.

Objective To demonstrate the noninferiority of the novel hemostatic agent, Hemofence (BMI Korea Co., Ltd., thrombin cross-linked sodium hyaluronate gel matrix) compared to the established agent, Floseal Hemostatic Matrix (Baxter, thrombin-gelatin matrix) in achieving hemostasis for spinal surgeries, with secondary objectives to assess additional efficacy and safety. Methods This clinical trial was a multicenter, randomized, subject-blinded, active-controlled, parallel-group, phase 3 study. Investigational drugs were administered to the first and second bleeding sites of each participant (or only to the first site if a second site was absent), evaluating hemostasis success rate within 10 minutes and the time to achieve hemostasis. Subsequent visits were conducted for safety assessments. For noninferiority test, a 97.5% one-sided confidence interval (CI) was used; the test group was deemed noninferior if the lower limit exceeded -10%. Results This trial showed a 97.10% success rate in the test group and 96.05% in the control group for primary efficacy. The 95% CI (-4.90% to 7.44%) confirmed the test drug’s noninferiority. Time to hemostasis showed no significant difference between groups. All adverse events, adverse drug reactions, and serious adverse events were statistically similar between groups (p=1.000, p=0.243, and p=0.966, respectively). Conclusion A novel hemostatic agent, Hemofence, demonstrated an efficacy and safety profile comparable to that of Floseal.

More and more studies indicate that the effects of quantum size and energy level statistics play a crucial role in the thermodynamic properties of ultrasmall metallic grains. This paper aims to investigate how they affect the specific heat of ultrasmall metallic grains in magnetic field. As the particle size decreases, fluctuation effects and the impact of energy level separation are becoming more and more important. The method of static path approximation (SPA) is adopted to handle the fluctuation effect. Random matrix theory (RMT) is adopted due to its successful description of the energy level of metal nanoparticles. The normalized specific heat of several typical temperatures and electron spins were taken in the calculation, and the results were analyzed. It was found that spin and the spin-orbit coupling affect the specific heat very obviously, and the suppressed high spin weakens the contribution of electrons to the heat capacity. [ABSTRACT FROM AUTHOR]

Linear temporal logic (LTL) formalism can ensure the correctness of mobile robot planning through concise, readable, and verifiable mission specifications. For uneven terrain, planning must consider motion constraints related to asymmetric slope traversability and maneuverability. However, even though model checker tools like the open-source Simple Promela Interpreter (SPIN) include search optimization techniques to address the state explosion problem, defining a global LTL property that encompasses both mission specifications and motion constraints on digital elevation models (DEMs) can lead to complex models and high computation times. In this article, we propose a system model that incorporates a set of uncrewed ground vehicle (UGV) motion constraints, allowing these constraints to be omitted from LTL model checking. This model is used in the LTL synthesizer for path planning, where an LTL property describes only the mission specification. Furthermore, we present a specific parameterization for path planning synthesis using a SPIN. We also offer two SPIN-efficient general LTL formulas for representative UGV missions to reach a DEM partition set, with a specified or unspecified order, respectively. Validation experiments performed on synthetic and real-world DEMs demonstrate the feasibility of the framework for complex mission specifications on DEMs, achieving a significant reduction in computation cost compared to a baseline approach that includes a global LTL property, even when applying appropriate search optimization techniques on both path planners. [ABSTRACT FROM AUTHOR]

The decays of the B meson into vector mesons, observed during the LHCb experiment, provide an ideal laboratory to investigate particle physics phenomena with quantum information theory methods. In this article, we focus on the decays yielding a pair of ϕ mesons to investigate the presence of entanglement in the spin correlations of the system and quantify the amount of Bell inequality violation it entails. Our results show that the present LHCb data allow access to entanglement and to the Bell inequality violation with a significance exceeding the 5 σ threshold in both the cases. This demonstrates that the strong and electroweak interactions responsible for the B meson decay act as a source of entanglement and the quantum mechanics nature of high-energy phenomena. Particular attention is paid to the assessment of loopholes: deficiencies in the experimental setup which could invalidate the results of the Bell test. [ABSTRACT FROM AUTHOR]

In chemistry and biochemistry, chirality represents the structural asymmetry characterized by nonsuperimposable mirror images for a material such as DNA. In physics, however, chirality commonly refers to the spin–momentum locking of a particle or quasiparticle in the momentum space. While seemingly disconnected, structural chirality in molecules and crystals can drive electronic chirality through orbital–momentum locking; that is, chirality can be transferred from the atomic geometry to electronic orbitals. Electronic chirality provides an insightful understanding of chirality-induced spin selectivity, in which electrons exhibit salient spin polarization after going through a chiral material, and electrical magnetochiral anisotropy, which is characterized by diode-like transport. It further gives rise to new phenomena, such as anomalous circularly polarized light emission, in which the light handedness relies on the emission direction. These chirality-driven effects will generate broad impacts for fundamental science and technology applications in spintronics, optoelectronics, and biochemistry. [ABSTRACT FROM AUTHOR]

Sexual dimorphism in prevalence, severity and genetic susceptibility exists for most common diseases. However, most genetic and clinical outcome studies are designed in sex-combined framework considering sex as a covariate. Few sex-specific studies have analyzed males and females separately, which failed to identify gene-by-sex interaction. Here, we propose a novel unified biologically interpretable deep learning-based framework (named SPIN) for sexual dimorphism analysis. We demonstrate that SPIN significantly improved the C-index up to 23.6% in TCGA cancer datasets, and it was further validated using asthma datasets. In addition, SPIN identifies sex-specific and -shared risk loci that are often missed in previous sex-combined/-separate analysis. We also show that SPIN is interpretable for explaining how biological pathways contribute to sexual dimorphism and improve risk prediction in an individual level, which can result in the development of precision medicine tailored to a specific individual's characteristics. [ABSTRACT FROM AUTHOR]

Within the confines of a two-fluid quantum magnetohydrodynamic model, the investigation of magnetoacoustic shock and solitary waves is conducted in an electron-ion magnetoplasma that considers electrons of spin 1/2. When the plasma system is nonlinearly investigated using the reductive perturbation approach, the Korteweg de Vries-Burgers (KdVB) equation is produced. Sagdeev's potential is created, revealing the presence of solitary solutions. However, when dissipative terms are included, intriguing physical solutions can be obtained. The KdVB equation is further investigated using the phase plane theory of a planar dynamical system to demonstrate the existence of periodic and solitary wave solutions. Predicting several classes of traveling wave solutions is advantageous due to various phase orbits, which manifest as soliton-shock waves, and oscillatory shock waves. The presence of a magnetic field, the density of electrons and ions, and the kinematic viscosity significantly alter the properties of magnetoacoustic solitary and shock waves. Additionally, electric fields have been identified. The outcomes obtained here can be applied to studying the nature of magnetoacoustic waves that are observed in compact astrophysical environments, where the influence of quantum spin phenomena remains significant, and also in controlled laboratory plasma experiments. [ABSTRACT FROM AUTHOR]

To identify, describe and account for the incidence of spin in systematic reviews and meta-analyses of tendon transfer for the treatment of massive, irreparable rotator cuff tears. The secondary objective was to characterize the studies in which spin was identified and to determine whether identifiable patterns exist among studies with spin. This study was conducted per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Each abstract was assessed for the presence of the 15 most common types of spin derived from a previously established methodology. General data that were extracted included study title, authors, publication year, journal, level of evidence, study design, funding source, reported adherence to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, preregistration of the study protocol, and methodologic quality per A Measurement Tool to Assess Systematic Reviews Version 2 (AMSTAR 2). The search yielded 53 articles, of which 13 were included in the final analysis. Articles were excluded if they were not published in a peer reviewed journal, not written in English, utilized cadaveric or nonhuman models, or lacked an abstract with accessible full text. 53.8% (7/13) of the included studies contained at least 1 type of spin in the abstract. Type 5 spin ("The conclusion claims beneficial effect of the experimental treatment despite a high risk of bias in primary studies") was the most common, appearing in 23.1% (3/13) of included abstracts. Nine of the spin categories did not appear in any of the included abstracts. A lower AMSTAR 2 score was significantly associated with the presence of spin in the abstract (P <.006). Spin is highly prevalent in the abstracts of systematic reviews and meta-analyses concerning tendon transfer for massive rotator cuff tears. A lower overall AMSTAR 2 rating was associated with a higher incidence of spin. Future studies should continue to explore the prevalence of spin in orthopedic literature and identify any factors that may contribute to its presence. [ABSTRACT FROM AUTHOR]

Introduction: Various types of noise have been used with speech material to assess speech perception in noise (SPIN) abilities. The literature suggests that speech identification varies with different types of background noise, and it has been reported that the target native language and the language of the babbling influence performance. Such efforts in an Indian context have not yet been reported. The aim of the study is to evaluate the speech perception in noise performance of Malayalam-speaking young adults with normal hearing using three different background noises. Material and methods: A repeated measure research design were adopted with a random sampling method. 30 native Malayalam speakers with normal hearing between the ages of 18 and 25 participated in the study. A standardized sentence list in Malayalam was used as the speech stimulus. Nine lists were chosen and randomly divided so that there were three lists to each background noise. Noises were speech spectrumshaped noise, non-native language multi-talker babble (Kannada), and native language multi-talker babble (Malayalam). Each successfully repeated keyword received a '1' and each incorrectly repeated word received a '0.' Because each sentence had four important words, each collection of 10 sentences scored a maximum of 40. The percentage of correct answers was determined and further analyzed. Results: Scores were significantly different in all three different background noises across different SNRs. The highest scores were obtained at +5 dB SNR and the poorest scores at --5 dB SNR. Among the three different background noises, native multi-talker babble (Malayalam) yielded better scores than non-native multi-talker babble (Kannada), followed last by speech spectrum-shaped noise. Conclusions: The findings of the current study may be attributed to the increased efficacy of speech spectrum noise due to its energetic masking characteristics and the similarity between the two languages in terms of its origin and acoustic-phonetic properties. [ABSTRACT FROM AUTHOR]

A class of quantum probabilities is reformulated in terms of non-Newtonian calculus and projective arithmetic. The model generalizes spin-1/2 singlet state probabilities discussed in Czachor (Acta Physica Polonica:139 70–83, 2021) to arbitrary spins s. For s → ∞ the formalism reduces to ordinary arithmetic and calculus. Accordingly, the limit "non-Newtonian to Newtonian" becomes analogous to the classical limit of a quantum theory. [ABSTRACT FROM AUTHOR]

This White Paper aims at highlighting the important benefits in the science reach of the EIC. High luminosity operation is generally desirable, as it enables producing and harvesting scientific results in a shorter time period. It becomes crucial for programs that would require many months or even years of operation at lower luminosity.

IntroductionOncology media websites such as Oncology Live (OncLive) and Targeted Oncology (TargetedOnc) play an important role in the dissemination of oncology news to patients and clinicians; however, the quality of the content on these websites has not been assessed. Our study aimed to analyze content from these websites and assess financial conflicts of interest (FCOI) amongst speakers interviewed on these websites.MethodsArticles published on OncLive and TargetedOnc during October 2021, were prospectively captured and analyzed. The primary outcome of our study was the quality of oncology news reporting in OncLive and TargetedOnc. We assessed the FCOI amongst speakers using data from Open Payments.ResultsWe examined 196 articles (OncLive 108, TargetedOnc 88). Limitations of cited research were reported in 7% (7/105) of OncLive and zero TargetedOnc articles. Benefit and risks in absolute numbers were reported in 28% (28/99) of OncLive and 16% (7/45) of TargetedOnc articles. Independent experts were quoted in 47% (51/108) and 51% (44/86) of the OncLive and TargetedOnc articles, respectively (Table 3). Pharmaceutical executives were quoted in 18% (20/108) and 11% (10/88) of OncLive and TargetedOnc articles, respectively. No FCOI disclosures were listed or reported for any articles. The mean general payment received from industry by United States physicians was $63,861 in 2019 and $39,639 in 2020.ConclusionOur study demonstrates low quality and potentially biased reporting of oncology news on OncLive and TargetedOnc. Careful safeguards, oversight and reporting of relevant FCOI are needed to maintain the quality and transparency of content being provided.

This paper investigates the relation between the Berry phase of a spinor accumulated along a path corresponding to an adiabatically varying magnetic field and the conformal deformation along the path in the parameter space. The first part demonstrates that the accumulated phase can be controlled by continuous deformation characterized by a single conformal parameter. The source of the corresponding field strength responsible for the deformed phase path is shown to be a conformally deformed monopole located at the origin in the parameter space with the fundamental strength g=±1/2. In the second part, we model a rotating magnetic field coupled to a charged spinor with a time-varying amplitude subjected to the conformal deformation, realizing a single-variable deformation of the evolution process of the phase path.

The process-oriented programming is a paradigm based on the process concept where each process is a concurrent finite state machine inside. The paradigm is intended for PLC (programmable logic controllers) developers to write Industry 4.0-enabled software. The poST language is a promising process-oriented extension of the IEC 61131-3 Structured Text (ST) language designed to provide a conceptual consistency of the PLC source code with technological description of the process under control. This language combines the advantages of FSM-based programming with the standard syntax of the ST language. We propose transformational semantics of poST providing rules for translation of poST language statements to Promela — the input language of the SPIN model checker. Following these semantic rules, our Xtext-based translator outputs a Promela model for the poST program. Our contribution is the poST transformational semantics and the method for automatic generation of the Promela code from poST control programs. The resulting Promela program is ready to be verified with SPIN model checker against linear temporal logic requirements to the source poST program. In the paper we provide an overview of related work, as well as a brief description of the poST and Promela languages. Further, the Promela poST translation rules cover control flow statements, process creation and state management constructs, and timeout management. Then we define service processes for modeling the external environment and managing high-level LTL specifications. Then we present the main ideas of implementing the translator poST to Promela. We also illustrate our approach using the example of a system for managing electricity consumption and production, including renewable sources.

Verification of real-time system properties using formal models can improve system design and quality. The Timed Petri net is a formal model for modelling and designing real-time systems with time constraints. Furthermore, model checking is a formal verification method used to verify system properties using model checkers. This article proposes an automated transformation system for mapping a Timed Petri net into one of the common model checkers, the SPIN PROMELA model, to verify real-time system properties. This approach enables the combination of two modelling paradigms and supports system verification using system design models. In this study, the system properties were verified using both the simulation method and linear temporal logic formulas supported by the SPIN model checker. Timed Petri net models of two different case studies, a central server computer system and a manufacturing Kanban system were considered to verify the boundedness, liveness and system behavioral properties using the proposed transformation system.

The nuanced role of spin effects remains a critical gap in designing proficient open‐shell catalysts. This study elucidates an iron‐catalyzed allylic C(sp3)−H silylation/alkyne hydrosilylation reaction, in which the spin state of the open‐shell iron catalyst dictates the reaction kinetics and pathway. Specifically, spin crossover led to alkyne hydrosilylation, whereas spin conservation resulted in a novel allylic C(sp3)−H silylation reaction. This chemoselectivity, governed by the spin‐crossover efficiency, reveals an unexpected dimension in spin effects and a first in the realm of transition‐metal‐catalyzed in situ silylation of allylic C(sp3)−H bonds, which had been previously inhibited by the heightened reactivity of alkenes in hydrosilylation reactions. Furthermore, this spin crossover can either accelerate or hinder the reaction at different stages within a single catalytic reaction, a phenomenon scarcely documented. Moreover, we identify a substrate‐assisted C−H activation mechanism, a departure from known ligand‐assisted processes, offering a fresh perspective on C−H activation strategies. [ABSTRACT FROM AUTHOR]

The utilization of a magnetic field to manipulate spin states has emerged as a novel approach to enhance efficiency in electrocatalytic reactions, distinguishing from traditional strategies that focus on tuning activation energy barriers. Currently, this approach is specifically tailored to reactions where spin states change during the catalytic process, such as the oxidation of singlet H2O to triplet O2. In the magnetically enhanced oxygen evolution reaction (OER) procedure, the parallel spin alignment on the ferromagnetic catalyst was induced by the external magnetic field, facilitating the triplet O−O bonding, which is the rate limiting step in OER. This review centers on recent advancements in harnessing external magnetic fields to enhance OER performance, delving into mechanistic approaches for this magnetic promotion. Additionally, we provide a summary of magnetic field application in other electrocatalytic reactions, including oxygen reduction, methanol oxidation, and CO2 reduction. [ABSTRACT FROM AUTHOR]

Background: Spin is a form of reporting bias which suggests a treatment is beneficial despite a statistically nonsignificant difference in outcomes. Our purpose was to define the prevalence of spin within the abstracts of distal radius fracture (DRF) systematic reviews (SRs) and meta-analyses (MA). We also sought to identify article characteristics that were more likely to contain spin. Methods: We performed a SR of multiple databases to identify DRF SRs and MAs. Articles were screened and analyzed by 3 reviewers. We recorded article and journal characteristics including adherence to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, funding disclosures, methodologic quality (AMSTAR 2 instrument), impact factor, and country of origin. Presence of the 9 most severe types of spin in abstracts were recorded. Unadjusted odds ratios (ORs) were calculated to analyze the association between article characteristics and the presence of spin. Results: A total of 112 articles were included. Spin was present in 46% of abstracts, with type 1 spin ("conclusions not supported by findings") most frequent (19%). Spin was present in 43% of abstracts in PRISMA-adhering journals compared to 49% in journals that did not (OR = 0.79, 95% confidence interval [CI] = 0.37-1.68). For articles originating from China, spin was present in 61% of abstracts compared to 39% of abstracts from other countries (OR = 2.55, 95% CI = 1.13-5.75). Conclusions: In addition to low article quality, there are high rates of spin within the abstracts of SRs and MAs related to treatment of DRF. Articles within journals that adhere to PRISMA do not appear to contain less spin. [ABSTRACT FROM AUTHOR]

Landauer's bound is applicable to irreversible quantum operations. In this study, we showcased that the Doppler temperature manifests the existence of Landauer's bound, which does not block a spin from (irreversibly) flipping with a tiny amount of energy via quantum tunneling. Verified by a spin–spin magnetic interaction experiment, this (energy) amount was determined to be only 1.25 times the theoretical value of Landauer's bound. Based on Heisenberg's principle, we defined information from a measuring perspective: one bit of information corresponds to the smallest error when quantifying the product of the measured energy uncertainty ( Δ E ) and the measured time duration ( Δ t ). We then illustrate an optically manipulated, spin-encoded, near-Landauer-bound, near-Heisenberg-limit quantum computer that encompasses this new definition of information. This study may represent the last piece of the puzzle in understanding both quantum Landauer erasure and Heisenberg's quantum limit since a single spin is the smallest information carrier. [ABSTRACT FROM AUTHOR]

In classical electrodynamics, the well-known Lorentz force law falls short of providing a satisfactory result for the trajectory of point-like charged particles when considering that particle's own self-force. While there have been many historical attempts, Gralla, Harte and Wald developed a new model for classical charged particles that is free from pathologies while being consistent with Maxwell's equations and conserves stress-energy. Expanding upon this approach, we derive a relativistically correct, modified Lorentz force law in vector form, which includes radiation reaction, and spin- and magnetic moment-dependent correction terms, suitable to be included in classical electrodynamics lectures and beam dynamics simulation tools. As by-products we obtain evolution equations for mass, spin angular momentum and the radiated power. We compare the new equations to the classical ones and use the new equations to conduct numerical simulations, showing that the results are free of any nonphysical artifacts, and which might be possible to test in future experiments at particle accelerators. The new equations foster improved insight into beam dynamics. [ABSTRACT FROM AUTHOR]

Researchers who conduct studies comparing the efficacy of two treatments often find that their preferred treatment outperforms the comparison treatment. This finding has been labelled the allegiance association. Although this association is robust, it is unclear whether it reflects an allegiance bias on the part of the researchers or whether it is noncausal, with researchers being allied to the more effective treatments. This study applied a quasi‐experimental method proposed by a previous study to 19 pairs of treatment comparison studies. Each member of a pair had used the same two psychotherapies to treat clients with the same disorder, but the researchers in each of the two studies had opposing allegiances. If the authors of one study in the pair concluded that their preferred treatment was superior and the authors of the other study concluded that their preferred treatment was superior or that the two treatments were equivalent, these patterns would suggest allegiance bias. In 10 of the 19 pairs, the patterns were consistent with the operation of an allegiance bias, indicating that although allegiance biases are not inevitable, they are ubiquitous. Practitioners and other psychotherapy research consumers should use caution when interpreting the findings from treatment comparison studies. [ABSTRACT FROM AUTHOR]

Molecular switches that reversibly change their structures and physical properties are important for applications such as sensing and information processing at molecular scales. In order to avoid the intermolecular aggregation that is often detrimental to the stimuli‐responses of molecular switches, previous studies of molecular switches have been often conducted in dilute solutions which are difficult for applications in solid‐state devices. Here we report molecular design and synthesis that integrates anthraquinodimethane as molecular switching units into polymers with amenable processibility in solid states. Optical and electron spin resonance characterizations indicate that the four‐arm polymers of poly(ϵ‐caprolactone) or poly(D,L‐lactide) tethered from anthraquinodimethane slow down the dynamics of the conformational switching between the folded and the twisted conformations, enhance the photoluminescence in solid states and impart materials with a small energy gap from singlet ground state to thermally accessible triplet state. [ABSTRACT FROM AUTHOR]

In April 2017, the Event Horizon telescope received an image of a supermassive black hole in the Sagittarius A* source. This image consists of a ring-like structure that contains three areas with increased brightness (spots). If we assume that these spots are associated with flares near the event horizon of a black hole, then we can estimate its spin. Our estimate gives a value of the order of . [ABSTRACT FROM AUTHOR]

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Study design: retrospective review. Objective: Enhanced Recovery After Surgery (ERAS) is a multidisciplinary set of evidence-based interventions to reduce morbidity and accelerate postoperative recovery. Complex spine surgery carries high risks of perioperative blood loss, blood transfusion, and suboptimal fluid states. This study evaluates the efficacy of a perioperative fluid and blood management component comprised of a restrictive transfusion policy, goal directed fluid management, number of tranexamic acid (TXA) utilization, and autologous blood transfusion within our ERAS protocol for complex spine surgery. Methods: A retrospective review compared patients undergoing elective complex spine surgery prior to and following implementation of an ERAS protocol with intraoperative blood and fluid management. Outcomes included incidence of blood transfusion, estimated blood loss, intraoperative crystalloids administered, frequency of intraoperative TXA utilized, incidence of patients extubated within the operating room (OR), intensive care unit (ICU) admission, and hospital length of stay. Results: Following implementation, the rate of blood transfusion decreased by 11.7%(P =.017) and average crystalloid infusion was reduced 680 mL per case(P <.001). Intraoperative blood loss decreased on average 342 mL per case(P =.001) and TXA use increased significantly by 25%(P <.001). Postoperative ICU admissions declined by 8.5%(P =.071); extubation within the OR increased by 13.3%(P =.005). Conclusions: This protocol presents a unique perspective with the inclusion of an interdisciplinary and comprehensive blood and fluid management protocol as an integral part of our ERAS pathway for complex spine surgery. These results indicate that a standardized approach is associated with reduced rates of blood transfusion and optimized fluid states which was correlated with decreased postoperative ICU admissions. [ABSTRACT FROM AUTHOR]

The magnetic dipole moment and the electric quadrupole moment are the nuclear moments that provide us with key information about the proton and neutron configurations in a nucleus and the shape of a nucleus, respectively. In the study of nuclear structure through the measurement of the nuclear moments, a technique to produce spin orientation of rare-isotope beams has played important roles. Recently, a scheme of the two-step projectile fragmentation was developed to produce high spin alignment in RI beams and was applied to the frontier of the study for nuclear structure of neutron-rich nuclei, such as 75 Cu and 99 Zr. The recent activities of the nuclear-moment measurements using highly spin-aligned beams at RIKEN RIBF are reported. [ABSTRACT FROM AUTHOR]

In this paper, we consider a spin 1/2 particle includes the Proton and Neutron interacting with time variable magnetic field and solve non-relativistic Schrodinger-Pauli equation. The study of occupation probability as function of time with choice of different values in coefficients of magnetic field vector and the competition between these coefficients will have interesting results in NMR spectroscopy. [ABSTRACT FROM AUTHOR]

Understanding the spin distribution in FeN4-doped graphene nanoribbons with zigzag and armchair terminations is crucial for tuning the electronic properties of graphene-supported non-platinum catalysts. Since the spin-polarized carbon and iron electronic states may act together to change the electronic properties of the doped graphene, we provide in this work a systematic evaluation using a periodic density-functional theory-based method of the variation of spin-moment distribution and electronic properties with the position and orientation of the FeN4 defects, and the edge terminations of the graphene nanoribbons. Antiferromagnetic and ferromagnetic spin ordering of the zigzag edges were considered. We reveal that the electronic structures in both zigzag and armchair geometries are very sensitive to the location of FeN4 defects, changing from semi-conducting (in-plane defect location) to half-metallic (at-edge defect location). The introduction of FeN4 defects at edge positions cancels the known dependence of the magnetic and electronic proper-ties of undoped graphene nanoribbons on their edge geometries. The implications of the reported results for catalysis are also discussed in view of the presented electronic and magnetic properties. [ABSTRACT FROM AUTHOR]

Reducing the overpotential of oxygen evolution reaction (OER) with slow kinetics is important to realize commercial hydrogen production from water electrolysis. Here, ZnCo 2 O 4 with abundant surface oxygen vacancies is employed to clarify the influence of oxygen vacancies on OER performance under AC magnetic field. The additional active sites as well as enhanced reaction activity of each active sites resulting from oxygen vacancies enable N–ZnCo 2 O 4-δ -350 to exhibit outstanding OER performance, where the overpotential is 406 mV at 10 mA cm−2. Furthermore, double exchange interaction between Co2+-O2--Co3+ ignited by oxygen vacancies produces ferromagnetism in N–ZnCo 2 O 4-δ , which can directly promote OER under ACMF. And the mass transport at additional active sites active sites provided by oxygen vacancies is also accelerated under ACMF due to magnetohydrodynamic convection. As a result, non-iR-corrected overpotential at 10 mA cm−2 of N–ZnCo 2 O 4-δ -350 is reduced to 243 mV when the ACMF intensity is 4.752 mT, which is a 44.5% reduction compared to no ACMF. These findings provide a novel and efficient perspective for realizing efficient electrocatalysis. [Display omitted] • Oxygen vacancy (O v) can optimize e g occupancy and induce built-in electric field. • Double exchange interaction caused by O v produces ferromagnetism in Co2+-O2--Co3+. • The overpotential (η 10) of N–ZnCo 2 O 4-δ -350 is reduced by 44.5% at 4.752 mT. • OER enhancement under AC magnetic field is related to convection and ferromagnetism. [ABSTRACT FROM AUTHOR]

Cricket is one of the most popular sports in the world. For the batters to practice, there could be a requirement for an effective and efficient device to mimic different bowling variations to enhance the training sessions. This research consists of computer aided design, simulation, and fabrication of a robust cricket bowling machine to achieve target bowling for effective training of cricket batters. A novel ball propelling mechanism was designed with two degrees of freedom movements of a pair of rotating wheels. Mechanisms for sudden speed changes were also tested with prototypes during this design. However, for acceptable product compactness and cost, the design was prototyped without the sudden speed changing concept. The base is maintained on a bi-axial precise tilting gyroscopic mechanism. This tilting mechanism accurately adjusts the delivery point of the ball with respect to a two-axis system, which helps to control the line and length of the ball. The novel ball propelling mechanism enhances the stability of controlling in pitching position, ball rotation axis, and ball speed. Controlling these parameters effectively creates an environment for efficient practice sessions for batsmen. Target bowling is the main objective of this study and the machine intends to mimic the vast bowling variations. [ABSTRACT FROM AUTHOR]

In this paper it is experimentally demonstrated that the electron‐spin/molecular‐handedness interaction plays a fundamental role in the chiral recognition process. This conclusion is inferred comparing current versus potential (I–V) curves recorded using chiral electrode surfaces, which are obtained via chemisorption of an enantiopure thiophene derivative: 3,3′‐bibenzothiophene core functionalized with 2,2′‐bithiophene wings (BT2T4). The chiral recognition capability of these chiral‐electrodes is probed via cyclic voltammetry measurements, where, Ag nanoparticles (AgNPs) capped with enantiopure BT2T4 (BT2T4@AgNP) are used as the chiral redox probe. Then, the interface handedness is explored by recording spin‐polarized I–V curves in spin‐dependent electrochemistry (SDE) and magnetic‐conductive atomic force microscopy (mc‐AFM) experiments. The quality of the interfaces is thoroughly cross‐checked using X‐ray photoemission spectroscopy, Raman, electrodesorption measurements, which further substantiate the metal(electrode)‐sulfur(thiophene) central role in the chemisorption process. Spin‐polarization values of about 15% and 30% are obtained in the case of SDE and mc‐AFM experiments, respectively. [ABSTRACT FROM AUTHOR]

Verification of real-time system properties using formal models can improve system design and quality. The Timed Petri net is a formal model for modelling and designing real-time systems with time constraints. Furthermore, model checking is a formal verification method used to verify system properties using model checkers. This article proposes an automated transformation system for mapping a Timed Petri net into one of the common model checkers, the SPIN PROMELA model, to verify real-time system properties. This approach enables the combination of two modelling paradigms and supports system verification using system design models. In this study, the system properties were verified using both the simulation method and linear temporal logic formulas supported by the SPIN model checker. Timed Petri net models of two different case studies, a central server computer system and a manufacturing Kanban system were considered to verify the boundedness, liveness and system behavioral properties using the proposed transformation system. [ABSTRACT FROM AUTHOR]

Clinical studies are often at risk of spin, a form of bias where beneficial claims are overstated while negative findings are minimized or dismissed. Spin is often more problematic in abstracts given their brevity and can result in the misrepresentation of a study's actual findings. The goal of this study is to aggregate primary and secondary studies reporting the clinical outcomes of the use of subacromial balloon spacers in the treatment of massive irreparable rotator cuff tears to identify the incidence of spin and find any significant association with study design parameters. This study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Independent searches were completed on 2 databases (PubMed and Embase) for primary studies, systematic and current concepts reviews, and meta-analyses and the results were compiled. Two authors independently screened the studies using a predetermined inclusion criteria and aggregated data including titles, publication journals and years, authors, study design, etc. Each study was independently assessed for the presence of 15 different types of spin. Statistical analysis was conducted to identify associations between study characteristics and spin. Twenty-nine studies met the inclusion criteria for our analysis, of which 10 were reviews or meta-analyses and 19 were primary studies. Spin was identified in every study except for 2 (27/29, 93.1%). Type 3 spin, "Selective reporting of or overemphasis on efficacy outcomes or analysis favoring the beneficial effect of the experimental intervention" and type 9 spin, "Conclusion claims the beneficial effect of the experimental treatment despite reporting bias" were most frequently noted in our study, both observed in 12/29 studies (41.4%). Date of publication, and adherence to Preferred Reporting Items for Systematic Reviews and Meta-Analyses or "The International Prospective Register of Systematic Reviews" were study characteristics associated with a higher rate of certain types of spin. There was a statistically significant association between disclosure of external study funding source and the presence of spin type 4, but none of the other forms of spin. Spin is highly prevalent in the abstracts of primary studies, systematic reviews, and meta-analyses discussing the use of subacromial balloon spacer technology in the treatment of massive irreparable rotator cuff tears. Our findings revealed that spin in the abstract tended to favor the balloon spacer intervention. Further efforts are required in the future to mitigate spin within the abstracts of published manuscripts. [ABSTRACT FROM AUTHOR]

Purpose: In the past decade, the biopolymeric properties of chitosan (CH) have been largely exploited for various applications. This paper aims to study the use of CH in its nanoform, i.e. as nanofibers blended with polyvinyl alcohol (PVA) for various antimicrobial applications in detail. In particular, their ability toward bacterial growth inhibition, in vitro drug release and their biocompatibility toward tissue growth have been investigated in detail. Design/methodology/approach: Electrospinning technique was adapted for depositing CH/PVA blended nanofilms on the silver foil under optimized conditions of high voltage. Three different concentrations of blended nanofiber samples were prepared and their antimicrobial properties were studied. Findings: The bead diameter and average diameter of blended nanofibers increase with CH concentration. Antibacterial activity increases as CH concentration increases. Increased hydrophilicity in CH-enriched samples contributes to a higher drug release profile. Originality/value: To the best of the authors' knowledge, chick chorioallantoic membrane assay analysis has been carried out for the first time for CH/PVA films which shows that CH/PVA blends are biocompatible. CH after being converted as nanoparticles exhibits higher drug release rate by in vitro method. [ABSTRACT FROM AUTHOR]