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5. The PPARƳ Agonist Protects Cardiomyocytes from Oxidative Stress and Apoptosis via Thioredoxin Overexpression.

Author

KIM, Yeon-Jung, PARK, Keon-Jea, SONG, Joong-Ki, SHIM, Tae-Jin, ISLAM, Kazi N., BAE, Jang-Whan, KIM, Sang-Min, LEE, Sang-Yeub, HWANG, Kyung-Kuk, KIM, Dong-Woon, CHO, Myeong-Chan, and RYU, Keun Ho

Subjects
ROSIGLITAZONE, HEART cells, POLYMERASE chain reaction, QUANTITATIVE research, WESTERN immunoblotting
Abstract

The article focuses on a study which examines the effectiveness of peroxisome proliferator activated receptor gamma (PPARy) agonist rosiglitazone (RSG) in protecting the apoptosis of rat cardiomyocytes (CMC). It mentions several techniques including statistical analysis, western blot analysis and polymerase chain reaction which are used as research methodologies. The result reveals that RSG increased the expression of TRx messenger RNA resulting in the protection of CMCs.

Published
2012
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