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5. 3 THE TIMES

Author

Harry, Blind, primary, Wedderburn, John, additional, Brooksbank, Mary, additional, Thomson, James Hall, additional, Little, Pippa, additional, McGonagall, William, additional, Dutton, G. F., additional, Lee, Joseph, additional, Smith, Stan, additional, Salmond, J. B., additional, Robertson, Gary, additional, Scroggie, Syd, additional, Taylor, Judith, additional, Montgomerie, William, additional, Thornbury, Walter, additional, Robb, Lydia, additional, Marra, Michael, additional, Armstrong, Kate, additional, McDonald, Ellie, additional, Adams, James, additional, McMillan, Hugh, additional, Geddes, James, additional, MacDonald, Anne, additional, Marsh, Henry, additional, Fraser, Bashabi, additional, Fitt, Matthew, additional, Foote, A. D., additional, Cameron, Athole, additional, Dallas, Robert Charles, additional, and Herbert, W. N., additional

Published
2019
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6. Reducing Synchronization Overhead Through Bundled Communication

Author

Dinan, James, Cole, Clement, Jost, Gabriele, Smith, Stan, Underwood, Keith, Wisniewski, Robert W., Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Poole, Stephen, editor, Hernandez, Oscar, editor, and Shamis, Pavel, editor

Published
2014
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10. State of Nature in Kent 2021

Author

Tinsley-Marshall, Paul, Skilbeck, Alana, Drake, Chris, Edwards, Chloe, Allen, Geoff, Atkinson, Keeley, Baker, Julia, Ball, Lawrence, Baur, Kathy, Beale, Sue, Bleet, Rosie, Bloor, Richard, Breeze, Lucy, Britton-Williams, Nicky, Buckingham, Sue, Butler, Maya, Clemmons, Lawrence, Culver, Eleanor, Easterbrook, Mike, Fitzmaurice, Amy, Griffiths, Andrea, Hadaway, Paul, Harding, Rory, Hazelhurst, Grant, Hayes, Matt, Heath, Marc, Hedley, Steve, Henderson, Andrew, Kirstoffer Hewitt, Hodges, Rick, Howard, Rufus, Hunt, Julia, Kitchener, Geoffrey, Mason-Baldwin, Lee, Moxey, Tricia, Orchard, Murray, Parr, Adrian, Pateman, Bethany, Peckham, Stephen, Phillips, Mike, Rainey, Maureen, Reid, Hannah, Russell-Smith, Tony, Ruyter, Alison, Shaw, Isabel, Shenton, Dave, Simmons, Hannah, Smith, Helen, Smith, Stan, Swinnerton, Kirsty Jane, Taylor, Pam, Thompson, Shirley, Tittley, Ian, Tuson, Dan, Walker, David, Weeks, Steve, Witts, Tony, and Young, John

Published
2022
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31. Integrated microfluidic system for rapid forensic DNA analysis: sample collection to DNA profile

Author

Hopwood, Andrew J., Hurth, Cedric, Yang, Jianing, Cai, Zhi, Moran, Nina, Lee-Edghill, John G., Nordquist, Alan, Lenigk, Ralf, Estes, Matthew D., Haley, John P., McAlister, Colin R., Chen, Xiaojia, Brooks, Carla, Smith, Stan, Elliott, Keith, Koumi, Pieris, Zenhausern, Frederic, and Tully, Gillian

Subjects
Microfluidics -- Research, DNA -- Chemical properties, Forensic sciences -- Research, Chemistry
Abstract

We demonstrate a conduit for the delivery of a step change in the DNA analysis process: A fully integrated instrument for the analysis of multiplex short tandem repeat DNA profiles from reference buccal samples is described and is suitable for the processing of such samples within a forensic environment such as a police custody suite or booking office. The instrument is loaded with a DNA processing cartridge which incorporates on-board pumps and valves which direct the delivery of sample and reagents to the various reaction chambers to allow DNA purification, amplification of the DNA by PCR, and collection of the amplified product for delivery to an integral CE chip. The fluorescently labeled product is separated using micro capillary electrophoresis with a resolution of 1.2 base pairs (bp) allowing laser induced fluorescence-based detection of the amplified short tandem repeat fragments and subsequent analysis of data to produce a DNA profile which is compatible with the data format of the UKDNA database. The entire process from taking the sample from a suspect, to database compatible DNA profile production can currently be achieved in less than 4 h. By integrating such an instrument and microfluidic cartridge with the forensic process, we believe it will be possible in the near future to process a DNA sample taken from an individual in police custody and compare the profile with the DNA profiles held on a DNA Database in as little as 3 h. 10.1021/ac101355r

Published
2010

33. Gubbins at a desk: Auden's Cave

Author

Smith, Stan

Subjects
Poets -- Works -- Criticism and interpretation, Poetry -- Criticism and interpretation, Literature/writing, Criticism and interpretation, Works
Abstract

What the World Likes There you go, writers all the time--the kind of people who are forever at home. Gubbins at a desk. It would do you good to understand [...]

Published
2009

34. Lines North

Author

Smith, Stan

Subjects
Sympathetic Magic (Book) -- Fewster, Brian, Lines North (Book) -- Corina, Pat, Books -- Book reviews, Ethnic, cultural, racial issues/studies, Literature/writing
Abstract

Lines North by Pat Corina (Soundswrite Press, 2008) 96 pp. ISBN 978-0-95507-861-3, 5.00 £ Sympathetic Magic by Brian Fewster (Poor Tom's Press, 2008) 92 pp. ISBN 978-0-95433-715-5, 6 £ Writing [...]

Published
2008

37. The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): study protocol for a randomized controlled trial

Author

Scherer, Roberta W., Drye, Lea, Lerner, Alan J., Gallagher, Damien, Dinoff, Adam, Vieira, Danielle, Bray, Jennifer, Abraham, Eleenor, Craft, Suzanne, Jenkins, Alecia, Dahl, Deborah, Rogers, Samantha, Sachs, Bonnie, Levey, Allan, Mann, Emily, Shaw, Edward, Sink, Kaycee, Caulder, Erin, Jefferson, Magie, Martin, Camilla, Shore, Kelsey, van Dyck, Christopher H., Kemp, Emily, Michalak, Hannah, Porsteinsson, Anton, Becker, Melinda, Pugh, Erika, Godek, Tyler, MacAvoy, Martha, Good, Susan, Ebner, Megan, McDonald, Julia, Ramanan, Srinath, Mecca, Adam, Lu, Oliver, ADMET 2 Research Group, Mintzer, Jacobo, Clark, David, Battjes-Siler, Debra, Smith, Stan, O'Neil, Courtney, Stocking, Nicole, Perin, Jamie, Shade, David, Jones, Jennifer, Holland, Stephanie, Wentz, Alicia, Chattopadhyay, Shumon, Grove, Bethany, Lanctôt, Krista, Herrera, Stephanie, Kaiser, Kristen, Lears, Andie, Broadnax, April, Mohammed, Aisha, Ryan, Laurie, McKelvy, Alvin, Elliott, Cerise, Rockwood, Kenneth, Edland, Steve, Rosenberg, Paul, Turner, Raymond Scott, Padala, Prasad, Hodges, Debbie, Jackson, Nicole, Padala, Kalpana, Burke, William, Batchuluun, Dawn, Burke, Anna, Grigaitis-Reyes, Michele, DiLise-Russo, Marjoire, Herrmann, Nathan, Vadovicky, Shelia, Favaro, Susan, Hernandez, Mary Lou, Autry, Lynn, Hoffmann, Nicole, Sanback, Rebecca, Lujan, Lazaro Martinez, Young, Elena, Lerner, Alan, Sami, Susie, Sanders, Marianne, Fatica, Parianne, Gross, Maria, Gore, Ethan, Mahajan, Supriya, Lah, James, Attis, Tamara, Cellar, Janet, Hales, Chad, Brawman-Mintzer, Olga, Walker, Margaret, Peterson-Hazan, Susan, Bolles, Erin, Carter, Erin, Marano, Chris, Dixon, Jasmine, Lawrence, Sarah, Schulz, Meghan, Burhanullah, Haroon, Salem-Spencer, Susan, Martin, Kim, Rice, Audrey, Kowalski, Nancy, Cervello, Michelle, Keltz, Melanie, Lane, Kaitlyn, Widman, Asa, Awkar, Anthony, O'Connell, Abigail, Williams, Arthur, Howland, Sheila, Hails, Alex, Orwat, Dennis, and Li, Abby

Subjects
medicine.medical_specialty, Time Factors, Apathy, Medicine (miscellaneous), Placebo, law.invention, 03 medical and health sciences, Study Protocol, 0302 clinical medicine, Quality of life, Randomized controlled trial, law, Alzheimer Disease, medicine, Dementia, Humans, Multicenter Studies as Topic, Pharmacology (medical), Psychiatry, Randomized Controlled Trials as Topic, lcsh:R5-920, 030214 geriatrics, business.industry, Methylphenidate, medicine.disease, United States, 3. Good health, Clinical trial, Treatment Outcome, Clinical Trials, Phase III as Topic, Clinical Global Impression, Central Nervous System Stimulants, medicine.symptom, business, lcsh:Medicine (General), 030217 neurology & neurosurgery, medicine.drug
Abstract

Alzheimer’s disease (AD) is characterized not only by cognitive and functional decline, but also often by the presence of neuropsychiatric symptoms. Apathy, which can be defined as a lack of motivation, is one of the most prevalent neuropsychiatric symptoms in AD and typically leads to a worse quality of life and greater burden for caregivers. Treatment options for apathy in AD are limited, but studies have examined the use of the amphetamine, methylphenidate. The Apathy in Dementia Methylphenidate Trial (ADMET) found that treatment of apathy in AD with methylphenidate was associated with significant improvement in apathy in two of three outcome measures, some evidence of improvement in global cognition, and minimal adverse events. However, the trial only enrolled 60 participants who were followed for only 6 weeks. A larger, longer-lasting trial is required to confirm these promising findings. The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2) is a phase III, placebo-controlled, masked, 6-month, multi-center, randomized clinical trial targeted to enroll 200 participants with AD and apathy. Participants are randomly assigned 1:1 to 20 mg methylphenidate per day prepared as four over-encapsulated tablets or to matching placebo. The primary outcomes include (1) the mean difference in the Neuropsychiatric Inventory Apathy subscale scores measured as change from baseline to 6 months, and (2) the odds of having a given rating or better on the modified AD Cooperative Study Clinical Global Impression of Change ratings at month 6 compared with the baseline rating. Other outcomes include change in cognition, safety, and cost-effectiveness measured at monthly follow-up visits up to 6 months. Given the prevalence of apathy in AD and its impact on both patients and caregivers, an intervention to alleviate apathy would be of great benefit to society. ADMET 2 follows on the promising results from the original ADMET to evaluate the efficacy of methylphenidate as a treatment for apathy in AD. With a larger sample size and longer follow up, ADMET 2 is poised to confirm or refute the original ADMET findings. ClinicalTrials.gov, NCT02346201 . Registered on 26 January 2015.

Published
2018

38. Epic logos: on last looking into several Homers

Author

Smith, Stan

Subjects
Logos (Philosophy) -- Criticism and interpretation, Literature/writing
Abstract

Fealty JOHN KEATS'S SONNET 'On First Looking into Chapman's Homer' charts a key moment in the construction of the modern subject, making that identification between subjectivity and language, a Logos [...]

Published
2006

39. Introduction: globalisation and its discontents

Author

Smith, Stan

Subjects
Globalization -- Political aspects -- Social aspects -- Influence, Anti-globalization movement -- Influence -- Political aspects -- Social aspects, Literature/writing
Abstract

Family Jokes: After the Fall 'IT'S A FAMILY JOKE', recalls Alex Portnoy in Philip Roth's Portnoy's Complaint, 'that when I was a tiny child I turned from the window out [...]

Published
2006

40. W.H. Auden

Author

Smith, Stan

Published
1995

46. Multi-isotope studies investigating recharge and inter-aquifer connectivity in coal seam gas areas (Qld, NSW) and shale gas areas (NT)

Author

Suckow, Axel, primary, Deslandes, Alec, additional, Gerber, Christoph, additional, Lamontagne, Sebastien, additional, Mallants, Dirk, additional, Davies, Philip, additional, Taylor, Andrew, additional, Wilske, Cornelia, additional, Smith, Stan, additional, Raiber, Matthias, additional, Meredith, Karina, additional, Rachakonda, Praveen Kumar, additional, Larcher, Alf, additional, Wilkes, Paul, additional, Prommer, Henning, additional, Siade, Adam, additional, and Barrett, Damian, additional

Published
2020
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49. Feasibility of internet training for care staff of residents with dementia: The CARES Program

Author

Hobday, John V., Savik, Kay, Smith, Stan, and Gaugler, Joseph E.

Subjects
Dementia -- Care and treatment, Dementia -- Research, Online education -- Usage, Online education -- Research, Nursing home patients -- Care and treatment, Nursing home patients -- Research, Medical personnel -- Training, Medical personnel -- Methods, Medical personnel -- Research, Health, Seniors
Published
2010

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