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As large-scale neural recordings become common, many neuroscientific investigations are focused on identifying functional connectivity from spatio-temporal measurements in two or more brain areas across multiple sessions. Spatial-temporal data in neural recordings can be represented as matrix-variate data, with time as the first dimension and space as the second. In this paper, we exploit the multiple matrix-variate Gaussian Graphical model to encode the common underlying spatial functional connectivity across multiple sessions of neural recordings. By effectively integrating information across multiple graphs, we develop a novel inferential framework that allows simultaneous testing to detect meaningful connectivity for a target edge subset of arbitrary size. Our test statistics are based on a group penalized regression approach and a high-dimensional Gaussian approximation technique. The validity of simultaneous testing is demonstrated theoretically under mild assumptions on sample size and non-stationary autoregressive temporal dependence. Our test is nearly optimal in achieving the testable region boundary. Additionally, our method involves only convex optimization and parametric bootstrap, making it computationally attractive. We demonstrate the efficacy of the new method through both simulations and an experimental study involving multiple local field potential (LFP) recordings in the Prefrontal Cortex (PFC) and visual area V4 during a memory-guided saccade task.

We deploy the new Arkenstone galactic wind model in cosmological simulations for the first time, allowing us to robustly resolve the evolution and impact of high specific energy winds. In a (25$\,h^{-1}\,$Mpc)$^3$ box we perform a set of numerical experiments that systematically vary the mass and energy loadings of such winds, finding that their energy content is the key parameter controlling the stellar to dark matter mass ratio. Increasing the mass loading, at fixed energy, actually results in mildly enhanced star formation, counter to prevailing wisdom but in agreement with recent analytic models. Of the simple parametrisations that we test, we find that an energy loading that scales inversely with halo mass best matches a wide range of observations, and can do so with mass loadings drastically lower than those in most previous cosmological simulations. In this scenario, much less material is ejected from the interstellar medium. Instead, winds both heat gas in the circumgalactic medium, slowing infall onto the galaxy, and also drive shocks beyond the virial radius, preventing accretion onto the halo in the first place. We have not yet tied the mass and energy loadings to high-resolution simulations (a key goal of the Learning the Universe collaboration); however, we can already report that a much lower fraction of the available supernova energy is needed in preventative galaxy regulation than required by ejective wind feedback models such as IllustrisTNG., Comment: Submitted to MNRAS. 19 pages, 14 figures. This is a Learning the Universe publication

Background: Advanced methods for causal inference, such as targeted maximum likelihood estimation (TMLE), require certain conditions for statistical inference. However, in situations where there is not differentiability due to data sparsity or near-positivity violations, the Donsker class condition is violated. In such situations, TMLE variance can suffer from inflation of the type I error and poor coverage, leading to conservative confidence intervals. Cross-validation of the TMLE algorithm (CVTMLE) has been suggested to improve on performance compared to TMLE in settings of positivity or Donsker class violations. We aim to investigate the performance of CVTMLE compared to TMLE in various settings. Methods: We utilised the data-generating mechanism as described in Leger et al. (2022) to run a Monte Carlo experiment under different Donsker class violations. Then, we evaluated the respective statistical performances of TMLE and CVTMLE with different super learner libraries, with and without regression tree methods. Results: We found that CVTMLE vastly improves confidence interval coverage without adversely affecting bias, particularly in settings with small sample sizes and near-positivity violations. Furthermore, incorporating regression trees using standard TMLE with ensemble super learner-based initial estimates increases bias and variance leading to invalid statistical inference. Conclusions: It has been shown that when using CVTMLE the Donsker class condition is no longer necessary to obtain valid statistical inference when using regression trees and under either data sparsity or near-positivity violations. We show through simulations that CVTMLE is much less sensitive to the choice of the super learner library and thereby provides better estimation and inference in cases where the super learner library uses more flexible candidates and is prone to overfitting., Comment: 20 pages, 3 figures, 1 table

Traditional star formation subgrid models implemented in cosmological galaxy formation simulations, such as that of Springel & Hernquist (2003, hereafter SH03), employ adjustable parameters to satisfy constraints measured in the local Universe. In recent years, however, theory and spatially-resolved simulations of the turbulent, multiphase, star-forming ISM have begun to produce new first-principles models, which when fully developed can replace traditional subgrid prescriptions. This approach has advantages of being physically motivated and predictive rather than empirically tuned, and allowing for varying environmental conditions rather than being tied to local Universe conditions. As a prototype of this new approach, by combining calibrations from the TIGRESS numerical framework with the Pressure-Regulated Feedback-Modulated (PRFM) theory, simple formulae can be obtained for both the gas depletion time and an effective equation of state. Considering galaxies in TNG50, we compare the "native" simulation outputs with post-processed predictions from PRFM. At TNG50 resolution, the total midplane pressure is nearly equal to the total ISM weight, indicating that galaxies in TNG50 are close to satisfying vertical equilibrium. The measured gas scale height is also close to theoretical equilibrium predictions. The slopes of the effective equations of states are similar, but with effective velocity dispersion normalization from SH03 slightly larger than that from current TIGRESS simulations. Because of this and the decrease in PRFM feedback yield at high pressure, the PRFM model predicts shorter gas depletion times than the SH03 model at high densities and redshift. Our results represent a first step towards implementing new, numerically calibrated subgrid algorithms in cosmological galaxy formation simulations., Comment: 33 pages, 12 figures, Accepted for publication in ApJ. This is a Learning the Universe Publication. All codes and data used to produce this work can be found at the following $\href{https://github.com/sultan-hassan/tng50-post-processing-prfm}{GitHub \,Link.}$

Arkenstone is a new scheme that allows multiphase, stellar feedback-driven winds to be included in coarse resolution cosmological simulations. The evolution of galactic winds and their subsequent impact on the circumgalactic medium are altered by exchanges of mass, energy, momentum, and metals between their component phases. These exchanges are governed by complex, small-scale physical processes that cannot be resolved in cosmological simulations. In this second presentation paper, we describe Arkenstone's novel cloud particle approach for modelling unresolvable cool clouds entrained in hot, fast winds. This general framework allows models of the cloud-wind interaction, derived from state-of-the-art high-resolution simulations, to be applied in a large-scale context. In this work, we adopt a cloud evolution model that captures simultaneous cloud mass loss to and gain from the ambient hot phase via turbulent mixing and radiative cooling, respectively. We demonstrate the scheme using non-cosmological idealized simulations of a galaxy with a realistic circumgalactic medium component, using the Arepo code. We show that the ability of a high-specific energy wind component to perform preventative feedback may be limited by heavy loading of cool clouds coupled into it. We demonstrate that the diverging evolution of clouds of initially differing masses leads to a complex velocity field for the cool phase and a cloud mass function that varies both spatially and temporally in a non-trivial manner. These latter two phenomena can manifest in the simulation because of our choice of a Lagrangian discretisation of the cloud population, in contrast to other proposed schemes. This is a Learning the Universe publication., Comment: Submitted to MNRAS. 27 pages, 11 figures. This is a Learning the Universe publication

Accurate classification of haematological cells is critical for diagnosing blood disorders, but presents significant challenges for machine automation owing to the complexity of cell morphology, heterogeneities of biological, pathological, and imaging characteristics, and the imbalance of cell type frequencies. We introduce CytoDiffusion, a diffusion-based classifier that effectively models blood cell morphology, combining accurate classification with robust anomaly detection, resistance to distributional shifts, interpretability, data efficiency, and superhuman uncertainty quantification. Our approach outperforms state-of-the-art discriminative models in anomaly detection (AUC 0.976 vs. 0.919), resistance to domain shifts (85.85% vs. 74.38% balanced accuracy), and performance in low-data regimes (95.88% vs. 94.95% balanced accuracy). Notably, our model generates synthetic blood cell images that are nearly indistinguishable from real images, as demonstrated by a Turing test in which expert haematologists achieved only 52.3% accuracy (95% CI: [50.5%, 54.2%]). Furthermore, we enhance model explainability through the generation of directly interpretable counterfactual heatmaps. Our comprehensive evaluation framework, encompassing these multiple performance dimensions, establishes a new benchmark for medical image analysis in haematology, ultimately enabling improved diagnostic accuracy in clinical settings. Our code is available at https://github.com/Deltadahl/CytoDiffusion.

We present new JWST observations of the nearby, prototypical edge-on, spiral galaxy NGC 891. The northern half of the disk was observed with NIRCam in its F150W and F277W filters. Absorption is clearly visible in the mid-plane of the F150W image, along with vertical dusty plumes that closely resemble the ones seen in the optical. A $\sim 10 \times 3~{\rm kpc}^2$ area of the lower circumgalactic medium (CGM) was mapped with MIRI F770W at 12 pc scales. Thanks to the sensitivity and resolution of JWST, we detect dust emission out to $\sim 4$ kpc from the disk, in the form of filaments, arcs, and super-bubbles. Some of these filaments can be traced back to regions with recent star formation activity, suggesting that feedback-driven galactic winds play an important role in regulating baryonic cycling. The presence of dust at these altitudes raises questions about the transport mechanisms at play and suggests that small dust grains are able to survive for several tens of million years after having been ejected by galactic winds in the disk-halo interface. We lay out several scenarios that could explain this emission: dust grains may be shielded in the outer layers of cool dense clouds expelled from the galaxy disk, and/or the emission comes from the mixing layers around these cool clumps where material from the hot gas is able to cool down and mix with these cool cloudlets. This first set of data and upcoming spectroscopy will be very helpful to understand the survival of dust grains in energetic environments, and their contribution to recycling baryonic material in the mid-plane of galaxies., Comment: Accepted for publication in Astronomy & Astrophysics; 16 pages, 8 figures

The Hartmann test is a method used to measure the wavefront error in a focal optical system, wherein a mask with a pattern of small holes is placed at the system's aperture stop. By taking an image at a defocused plane, the differences between the ideal and real positions of the reimaged holes (called the transverse ray aberrations) can be measured, which can then be used to estimate the wavefront error. However, the Hartmann test is usually used with an on-axis field. In this paper, we present a wavefront sensing method which generalizes the classical Hartmann test for off-axis field angles and arbitrary reference wavefronts. Our method involves taking images at two defocused planes, and then using the real reimaged hole positions on both planes to estimate the trajectories of rays from the system's exit pupil, at which the reference wavefront is situated. We then propagate the rays forward from the reference wavefront to one of the two defocused planes, in order to find the ideal reimaged hole positions, from which we can compute transverse ray aberrations. We derive and solve a pair of nonlinear partial differential equations relating transverse ray aberrations to wavefront error, using Zernike decomposition and nonlinear least squares. Our method has been verified on simulated data from the 7-lens f/2.25 red camera system of the GMT-Consortium Large Earth Finder (G-CLEF), a high resolution optical echelle spectrograph which will be a first light instrument for the Giant Magellan Telescope (GMT)., Comment: 18 pages, 23 figures, SPIE Astronomical Telescopes + Instrumentation 2024

Efficiently handling Automatic Identification System (AIS) data is vital for enhancing maritime safety and navigation, yet is hindered by the system's high volume and error-prone datasets. This paper introduces the Automatic Identification System Database (AISdb), a novel tool designed to address the challenges of processing and analyzing AIS data. AISdb is a comprehensive, open-source platform that enables the integration of AIS data with environmental datasets, thus enriching analyses of vessel movements and their environmental impacts. By facilitating AIS data collection, cleaning, and spatio-temporal querying, AISdb significantly advances AIS data research. Utilizing AIS data from various sources, AISdb demonstrates improved handling and analysis of vessel information, contributing to enhancing maritime safety, security, and environmental sustainability efforts.

Submillimeter and millimeter wavelengths provide a unique view of the Universe, from the gas and dust that fills and surrounds galaxies to the chromosphere of our own Sun. Current single-dish facilities have presented a tantalising view of the brightest (sub-)mm sources, and interferometers have provided the exquisite resolution necessary to analyse the details in small fields, but there are still many open questions that cannot be answered with current facilities. In this report we summarise the science that is guiding the design of the Atacama Large Aperture Submillimeter Telescope (AtLAST). We demonstrate how tranformational advances in topics including star formation in high redshift galaxies, the diffuse circumgalactic medium, Galactic ecology, cometary compositions and solar flares motivate the need for a 50m, single-dish telescope with a 1-2 degree field of view and a new generation of highly multiplexed continuum and spectral cameras. AtLAST will have the resolution to drastically lower the confusion limit compared to current single-dish facilities, whilst also being able to rapidly map large areas of the sky and detect extended, diffuse structures. Its high sensitivity and large field of view will open up the field of submillimeter transient science by increasing the probability of serendipitous detections. Finally, the science cases listed here motivate the need for a highly flexible operations model capable of short observations of individual targets, large surveys, monitoring programmes, target of opportunity observations and coordinated observations with other observatories. AtLAST aims to be a sustainable, upgradeable, multipurpose facility that will deliver orders of magnitude increases in sensitivity and mapping speeds over current and planned submillimeter observatories., Comment: 47 pages, 12 figures. For further details on AtLAST see https://atlast.uio.no

Sub-mm and mm wavelengths provide a unique view of the Universe, from the gas and dust that fills and surrounds galaxies to the chromosphere of our own Sun. Current single-dish facilities have presented a tantalising view of the brightest (sub-)mm sources, and interferometers have provided the exquisite resolution necessary to analyse the details in small fields, but there are still many open questions that cannot be answered with current facilities: Where are all the baryons? How do structures interact with their environments? What does the time-varying (sub-)mm sky look like? In order to make major advances on these questions and others, what is needed now is a facility capable of rapidly mapping the sky spatially, spectrally, and temporally, which can only be done by a high throughput, single-dish observatory. An extensive design study for this new facility is currently being undertaken. In this paper, we focus on the key science drivers and the requirements they place on the observatory. As a 50m single dish telescope with a 1-2{\deg} field of view, the strength of the Atacama Large Aperture Submillimeter Telescope (AtLAST) is in science where a large field of view, highly multiplexed instrumentation and sensitivity to faint large-scale structure is important. AtLAST aims to be a sustainable, upgradeable, multipurpose facility that will deliver orders of magnitude increases in sensitivity and mapping speeds over current and planned telescopes., Comment: 12 pages, Conference proceedings paper for the 2024 SPIE Astronomical Telescopes + Instrumentation meeting

The study of transient and variable events, including novae, active galactic nuclei, and black hole binaries, has historically been a fruitful path for elucidating the evolutionary mechanisms of our universe. The study of such events in the millimeter and submillimeter is, however, still in its infancy. Submillimeter observations probe a variety of materials, such as optically thick dust, which are hard to study in other wavelengths. Submillimeter observations are sensitive to a number of emission mechanisms, from the aforementioned cold dust, to hot free-free emission, and synchrotron emission from energetic particles. Study of these phenomena has been hampered by a lack of prompt, high sensitivity submillimeter follow-up, as well as by a lack of high-sky-coverage submillimeter surveys. In this paper, we describe how the proposed Atacama Large Aperture Submillimeter Telescope (AtLAST) could fill in these gaps in our understanding of the transient universe. We discuss a number of science cases that would benefit from AtLAST observations, and detail how AtLAST is uniquely suited to contributing to them. In particular, AtLAST's large field of view will enable serendipitous detections of transient events, while its anticipated ability to get on source quickly and observe simultaneously in multiple bands make it also ideally suited for transient follow-up. We make theoretical predictions for the instrumental and observatory properties required to significantly contribute to these science cases, and compare them to the projected AtLAST capabilities. Finally, we consider the unique ways in which transient science cases constrain the observational strategies of AtLAST, and make prescriptions for how AtLAST should observe in order to maximize its transient science output without impinging on other science cases., Comment: 19 pages, 5 figures

During the most active period of star formation in galaxies, which occurs in the redshift range 1

The study of planets and small bodies within our Solar System is fundamental for understanding the formation and evolution the Earth and other planets. Compositional and meteorological studies of the giant planets provide a foundation for understanding the nature of the most commonly observed exoplanets, while spectroscopic observations of the atmospheres of terrestrial planets, moons, and comets provide insights into the past and present-day habitability of planetary environments, and the availability of the chemical ingredients for life. While prior and existing (sub)millimeter observations have led to major advances in these areas, progress is hindered by limitations in the dynamic range, spatial and temporal coverage, as well as sensitivity of existing telescopes and interferometers. Here, we summarize some of the key planetary science use cases that factor into the design of the Atacama Large Aperture Submillimeter Telescope (AtLAST), a proposed 50-m class single dish facility: (1) to more fully characterize planetary wind fields and atmospheric thermal structures, (2) to measure the compositions of icy moon atmospheres and plumes, (3) to obtain detections of new, astrobiologically relevant gases and perform isotopic surveys of comets, and (4) to perform synergistic, temporally-resolved measurements in support of dedicated interplanetary space missions. The improved spatial coverage (several arcminutes), resolution ($\sim1.2''-12''$), bandwidth (several tens of GHz), dynamic range ($\sim10^5$) and sensitivity ($\sim1$ mK km s$^{-1}$) required by these science cases would enable new insights into the chemistry and physics of planetary environments, the origins of prebiotic molecules and the habitability of planetary systems in general., Comment: Submitted to Open Research Europe (AtLAST collection). 19 pages

Understanding the physical processes that regulate star formation and galaxy evolution are major areas of activity in modern astrophysics. Nearby galaxies offer unique opportunities to inspect interstellar medium (ISM), star formation (SF), radiative, dynamic and magnetic physics in great detail from sub-galactic (kpc) scales to sub-cloud (sub-pc) scales, from quiescent galaxies to starbursts, and from field galaxies to overdensities. In this case study, we discuss the major breakthroughs in this area of research that will be enabled by the Atacama Large Aperture Submillimeter Telescope (AtLAST), a proposed 50-m single-dish submillimeter telescope. The new discovery space of AtLAST comes from its exceptional sensitivity, in particular to extended low surface brightness emission, a very large 2 degree field of view, and correspondingly high mapping efficiency. This paper focuses on four themes which will particularly benefit from AtLAST: 1) the LMC and SMC, 2) extragalactic magnetic fields, 3) the physics and chemistry of the interstellar medium, and 4) star formation and galaxy evolution. With ~1000-2000h surveys each, AtLAST could deliver deep dust continuum maps of the entire LMC and SMC fields at parsec-scale resolution, high-resolution maps of the magnetic field structure, gas density, temperature and composition of the dense and diffuse ISM in ~100 nearby galaxies, as well as the first large-scale blind CO survey in the nearby Universe, delivering molecular gas masses for up to 10^6 galaxies (3 orders of magnitude more than current samples). Through such observing campaigns, AtLAST will have a profound impact on our understanding of the baryon cycle and star formation across a wide range of environments., Comment: 29 pages, 11 figues, submitted to Open Research Europe as part of the AtLAST collection: https://open-research-europe.ec.europa.eu/collections/atlast/about

Our knowledge of galaxy formation and evolution has incredibly progressed through multi-wavelength observational constraints of the interstellar medium (ISM) of galaxies at all cosmic epochs. However, little is known about the physical properties of the more diffuse and lower surface brightness reservoir of gas and dust that extends beyond ISM scales and fills dark matter haloes of galaxies up to their virial radii, the circumgalactic medium (CGM). New theoretical studies increasingly stress the relevance of the latter for understanding the feedback and feeding mechanisms that shape galaxies across cosmic times, whose cumulative effects leave clear imprints into the CGM. Recent studies are showing that a -- so far unconstrained -- fraction of the CGM mass may reside in the cold (T < 1e4 K) molecular and atomic phase, especially in high-redshift dense environments. These gas phases, together with the warmer ionised phase, can be studied in galaxies from z ~ 0 to z ~ 10 through bright far-infrared and sub-millimeter emission lines such as [C II] 158${\mu}$m, [O III] 88 ${\mu}$m, [C I] 609${\mu}$m, [C I] 370${\mu}$m, and the rotational transitions of CO. Imaging such hidden cold CGM can lead to a breakthrough in galaxy evolution studies but requires a new facility with the specifications of the proposed Atacama Large Aperture Submillimeter Telescope (AtLAST). In this paper, we use theoretical and empirical arguments to motivate future ambitious CGM observations with AtLAST and describe the technical requirements needed for the telescope and its instrumentation to perform such science., Comment: Submitted to Open Research Europe as part of the AtLAST collection: https://open-research-europe.ec.europa.eu/collections/atlast/about

Observations at (sub-)millimeter wavelengths offer a complementary perspective on our Sun and other stars, offering significant insights into both the thermal and magnetic composition of their chromospheres. Despite the fundamental progress in (sub-)millimeter observations of the Sun, some important aspects require diagnostic capabilities that are not offered by existing observatories. In particular, simultaneously observations of the radiation continuum across an extended frequency range would facilitate the mapping of different layers and thus ultimately the 3D structure of the solar atmosphere. Mapping large regions on the Sun or even the whole solar disk at a very high temporal cadence would be crucial for systematically detecting and following the temporal evolution of flares, while synoptic observations, i.e., daily maps, over periods of years would provide an unprecedented view of the solar activity cycle in this wavelength regime. As our Sun is a fundamental reference for studying the atmospheres of active main sequence stars, observing the Sun and other stars with the same instrument would unlock the enormous diagnostic potential for understanding stellar activity and its impact on exoplanets. The Atacama Large Aperture Submillimeter Telescope (AtLAST), a single-dish telescope with 50\,m aperture proposed to be built in the Atacama desert in Chile, would be able to provide these observational capabilities. Equipped with a large number of detector elements for probing the radiation continuum across a wide frequency range, AtLAST would address a wide range of scientific topics including the thermal structure and heating of the solar chromosphere, flares and prominences, and the solar activity cycle. In this white paper, the key science cases and their technical requirements for AtLAST are discussed., Comment: 14 pages, 4 figures, submitted to Open Research Europe as part of a collection on the Atacama Large Aperture Submillimeter Telescope (AtLAST)

As we learn more about the multi-scale interstellar medium (ISM) of our Galaxy, we develop a greater understanding for the complex relationships between the large-scale diffuse gas and dust in Giant Molecular Clouds (GMCs), how it moves, how it is affected by the nearby massive stars, and which portions of those GMCs eventually collapse into star forming regions. The complex interactions of those gas, dust and stellar populations form what has come to be known as the ecology of our Galaxy. Because we are deeply embedded in the plane of our Galaxy, it takes up a significant fraction of the sky, with complex dust lanes scattered throughout the optically recognisable bands of the Milky Way. These bands become bright at (sub-)millimetre wavelengths, where we can study dust thermal emission and the chemical and kinematic signatures of the gas. To properly study such large-scale environments, requires deep, large area surveys that are not possible with current facilities. Moreover, where stars form, so too do planetary systems, growing from the dust and gas in circumstellar discs, to planets and planetesimal belts. Understanding the evolution of these belts requires deep imaging capable of studying belts around young stellar objects to Kuiper belt analogues around the nearest stars. Here we present a plan for observing the Galactic Plane and circumstellar environments to quantify the physical structure, the magnetic fields, the dynamics, chemistry, star formation, and planetary system evolution of the galaxy in which we live with AtLAST; a concept for a new, 50m single-dish sub-mm telescope with a large field of view which is the only type of facility that will allow us to observe our Galaxy deeply and widely enough to make a leap forward in our understanding of our local ecology., Comment: 27 pages, submitted to Open Research Europe as part of the AtLAST collection: https://open-research-europe.ec.europa.eu/collections/atlast/about

An omnipresent feature of the multi-phase ``cosmic web'' is that warm/hot (>$10^5$ K) ionized gas pervades it. This gas constitutes a relevant contribution to the overall universal matter budget across multiple scales, from the several tens of Mpc-scale IGM filaments, to the Mpc ICM, all the way down to the CGM surrounding individual galaxies, on scales from ~1 kpc up to their respective virial radii (~100 kpc). The study of the hot baryonic component of cosmic matter density represents a powerful means for constraining the intertwined evolution of galactic populations and large-scale cosmological structures, for tracing the matter assembly in the Universe and its thermal history. To this end, the SZ effect provides the ideal observational tool for measurements out to the beginnings of structure formation. The SZ effect is caused by the scattering of the photons from the cosmic microwave background off the hot electrons embedded within cosmic structures, and provides a redshift-independent perspective on the thermal and kinematic properties of the warm/hot gas. Still, current and future (sub)mm facilities have been providing only a partial view of the SZ Universe due to any combination of: limited angular resolution, spectral coverage, field of view, spatial dynamic range, sensitivity. In this paper, we motivate the development of a wide-field, broad-band, multi-chroic continuum instrument for the Atacama Large Aperture Submillimeter Telescope (AtLAST) by identifying the scientific drivers that will deepen our understanding of the complex thermal evolution of cosmic structures. On a technical side, this will necessarily require efficient multi-wavelength mapping of the SZ signal with an unprecedented spatial dynamic range (from arcsecond to degree scales) and we employ theoretical forecasts to determine the key instrumental constraints for achieving our goals. [abridged], Comment: 29 pages, 17 figures, 1 table. Submitted to Open Research Europe as part of the AtLAST Design Study collection: https://open-research-europe.ec.europa.eu/collections/atlast/about. Comments are welcome

Here we present the cloud population extracted from M51, following the application of our new high-resolution dust extinction technique to the galaxy (Faustino Vieira et al. 2023). With this technique, we are able to image the gas content of the entire disc of M51 down to 5 pc (0.14"), which allows us to perform a statistical characterisation of well-resolved molecular cloud properties across different large-scale dynamical environments and with galactocentric distance. We find that cloud growth is promoted in regions in the galaxy where shear is minimised; i.e. clouds can grow into higher masses (and surface densities) inside the spiral arms and molecular ring. We do not detect any enhancement of high-mass star formation towards regions favourable to cloud growth, indicating that massive and/or dense clouds are not the sole ingredient for high-mass star formation. We find that in the spiral arms there is a significant decline of cloud surface densities with increasing galactocentric radius, whilst in the inter-arm regions they remain relatively constant. We also find that the surface density distribution for spiral arm clouds has two distinct behaviours in the inner and outer galaxy, with average cloud surface densities at larger galactocentric radii becoming similar to inter-arm clouds. We propose that the tidal interaction between M51 and its companion (NGC 5195) - which heavily affects the nature of the spiral structure - might be the main factor behind this., Comment: MNRAS accepted, 20 pages, 16 figures

The presence of short-lived radioisotopes (SLRs) 26-Al and 60-Fe in the Solar system places constraints on the initial conditions of our planetary system. Most theories posit that the origin of 26-Al and 60-Fe is in the interiors of massive stars, and they are either delivered directly to the protosolar disc from the winds and supernovae of the massive stars, or indirectly via a sequential star formation event. However, massive stars that produce SLRs also emit photoionising far and extreme ultraviolet radiation, which can destroy the gas component of protoplanetary discs, possibly precluding the formation of gas giant planets like Jupiter and Saturn. Here, we perfom N-body simulations of star-forming regions and determine whether discs that are enriched in SLRs can retain enough gas to form Jovian planets. We find that discs are enriched and survive the photoionising radiation only when the dust radius of the disc is fixed and not allowed to move inwards due to the photoevaporation, or outwards due to viscous spreading. Even in this optimal scenario, not enough discs survive until the supernovae of the massive stars and so have zero or very little enrichment in 60-Fe. We therefore suggest that the delivery of SLRs to the Solar system may not come from the winds and supernovae of massive stars., Comment: 13 pages, 4 figures, accepted for publication in MNRAS

We present a new dust extinction technique with which we are able to retrieve parsec-scale gas surface density maps for entire nearby galaxies. The method measures the dust attenuation in optical bands on a pixel-by-pixel basis against a smoothed, reconstructed stellar distribution. The contribution of foreground light along the line-of-sight is calibrated using dust emission observations, assuming that the dust sits in a layer close to the mid-plane of the face-on galaxy. Here, we apply this technique to M51 (NGC 5194) as a proof-of-concept, obtaining a resolution of 0.14" (5 pc). Our dust (and gas) surface density map is consistent with independent dust- and CO-based studies at lower resolution. We find that discrepancies between our estimates of surface density and other studies stem primarily from the choice of dust model (i.e. different dust absorption coefficients). When assuming the same dust opacity law, our technique produces surface densities that are consistent with independent studies. This dust extinction technique provides us with gas surface density maps at an unprecedented resolution for full disc coverage studies of nearby galaxies. The resulting well-resolved spatial information opens the possibility for more in-depth examination of the influence of large-scale dynamics (and also stellar feedback mechanisms) on the interstellar medium at parsec-scales, and consequently star formation in nearby galaxies., Comment: MNRAS accepted. 15 pages, 12 figures