1. COVID-19 vaccine is here: practical considerations for clinical imaging applications
- Author
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Ali Gholamrezanezhad, Sanaz Katal, and Arshia Pouraryan
- Subjects
and promotion of well-being ,030218 nuclear medicine & medical imaging ,Imaging modalities ,Imaging ,0302 clinical medicine ,Clinical imaging ,Tomography ,Computed tomography ,Lung ,Computed tomography (CT) ,Vaccination ,Immune cells ,CT, Computed Tomography ,SUVmax, maximum Standardized Uptake Value ,Single-photon emission computed tomography ,Magnetic Resonance Imaging ,X-Ray Computed ,Nuclear Medicine & Medical Imaging ,Editorial ,GGOs, ground-glass opacities ,3.4 Vaccines ,Radiology Nuclear Medicine and imaging ,030220 oncology & carcinogenesis ,Positron emission tomography (PET) ,Biomedical Imaging ,SPECT, Single Photon Emission Computed Tomography ,Infection ,Biotechnology ,Positron emission tomography ,2019-20 coronavirus outbreak ,medicine.medical_specialty ,COVID-19 Vaccines ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Clinical Sciences ,MRI, Magnetic Resonance Imaging ,PET, positron emission tomography ,Vaccine Related ,03 medical and health sciences ,Magnetic resonance imaging ,Single-photon emission computed tomography (SPECT) ,Radiologists ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Medical physics ,Magnetic resonance imaging (MRI) ,Lymph node activation ,business.industry ,SARS-CoV-2 ,Prevention ,COVID-19 ,Prevention of disease and conditions ,ALV, Aerated Lung Volume ,HMPAO, Hexamethyl Propylene Amine Oxime ,Good Health and Well Being ,Vaccine Potency ,SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2 ,Immunization ,SIRV, Shoulder Injuries Related to Vaccines ,business ,Tomography, X-Ray Computed ,COVID-19, Novel Coronavirus Disease - Abstract
Imaging tools are potentially able to provide valuable data regarding the development of an efficient vaccine against viral diseases. Tracking immune cells in vivo by imaging modalities can help us understand the intrinsic behaviors of immune cells in response to vaccine components. Imaging patterns at the vaccination site and draining lymph nodes might provide useful information about the vaccine potency. Besides, serial lung CT imaging has been purposed to evaluate vaccine efficiency regarding its protection against typical lung lesions of viral pneumonias. On the other hand, vaccination causes various confusing radiologic patterns that pose diagnostic challenges for clinicians and pitfalls for reading radiologists. This manuscript reviews potential applications of imaging modalities in the process of vaccine development and also goes over some of the imaging findings/pitfalls following vaccination., Highlights • Imaging tools could track the immune cell dynamics in vivo, which holds valuable research attention in the vaccination field. • Serial CT imaging might be a great indicator of vaccine efficiency in research setting. • Vaccination causes various confusing radiologic patterns that pose diagnostic challenges for clinicians and radiologists.
- Published
- 2021