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4,883 results on '"SHERMAN, M."'

1. Evaluating the Performance of Island Kitchen Range Hoods

Author: Walker, IS, Rojas, G, Clark, J, and Sherman, M
Subjects: Indoor Air Quality, Kitchen Ventilation, Cooking, Range Hood, Performance Standard
Abstract: A key aspect of achieving acceptable indoor air quality is source control. Cooking has been recognized as a significant source of pollutants for health impacts (e.g., PM2.5 and NO2) as well as moisture and odour. A common method of controlling this pollutant source is by using a range (or cooker) hood that vents to outside. However, field and laboratory experiments have shown highly variable performance for these devices. We use the capture efficiency metric (the fraction of the pollutants that are exhausted to outside at steady state) to characterize the range hood performance. To address this issue and provide useful information for builders, contractors, designers and home occupants, a laboratory rating method for range hood capture efficiency has recently been developed by LBNL and ASTM. The test method uses standardized emitters to create a heated plume and seed it with tracer gas. The tracer gas measurements in the room, the range hood exhaust and in the ambient air are used to estimate capture efficiency. However, this test method only applies to wall-mounted range hoods. Some range hoods are not wall-mounted: island range hoods are designed to operate over a cooktop in the middle of a room rather than against a wall and downdraft hoods draw air from near the cooktop rather than overhead. This paper discusses the development of a new test apparatus for island and downdraft hoods and presents measured capture efficiency data from example hoods. The results of this work will be used in future revisions to the ASTM standard.
Published: 2023

2. Residential Smart Ventilation: A Review

Author: Walker, IS, Guyot, G, Sherman, M, and Jordan, C
Published: 2023

3. Deep Synoptic Array Science: First FRB and Host Galaxy Catalog

Author: Law, C. J., Sharma, K., Ravi, V., Chen, G., Catha, M., Connor, L., Faber, J. T., Hallinan, G., Harnach, C., Hellbourg, G., Hobbs, R., Hodge, D., Hodges, M., Lamb, J. W., Rasmussen, P., Sherman, M. B., Shi, J., Simard, D., Squillace, R., Weinreb, S., Woody, D. P., and Yadlapalli, N.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Astrophysics of Galaxies
Abstract: Fast Radio Bursts (FRBs) are a powerful and mysterious new class of transient that are luminous enough to be detected at cosmological distances. By associating FRBs to host galaxies, we can measure intrinsic and environmental properties that test FRB origin models, in addition to using them as precise probes of distant cosmic gas. The Deep Synoptic Array (DSA-110) is a radio interferometer built to maximize the rate at which it can simultaneously detect and localize FRBs. Here, we present the first sample of FRBs and host galaxies discovered by the DSA-110. This sample of 11 FRBs is the largest, most uniform sample of localized FRBs to date, as it is selected based on association to host galaxies identified in optical imaging by Pan-STARRS1. These FRBs have not been observed to repeat and their radio properties (dispersion, temporal scattering, energy) are similar to that of the known non-repeating FRB population. Most host galaxies have ongoing star formation, as has been identified before for FRB hosts. Two hosts of the new sample are massive, quiescent galaxies. The distribution of star-formation history across this host-galaxy sample shows that the delay-time distribution is wide, with a powerlaw model that spans from $\sim100$\,Myr to $\gtrsim2$\,Gyr. This requires the existence of one or more progenitor formation channels associated with old stellar populations, such as the binary evolution of compact objects., Comment: 21 pages. Submitted to AAS Journals. Includes changes based on referee comments and improved host galaxy analysis
Published: 2023

4. The LHCb upgrade I

Author: LHCb collaboration, Aaij, R., Abdelmotteleb, A. S. W., Beteta, C. Abellan, Abudinén, F., Achard, C., Ackernley, T., Adeva, B., Adinolfi, M., Adlarson, P., Afsharnia, H., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F., Alexander, M., Albero, A. Alfonso, Aliouche, Z., Cartelle, P. Alvarez, Amalric, R., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andersson, M., Andreani, A., Andreianov, A., Andreotti, M., Andreou, D., Andrews, J. E., Anelli, M., Anjam, A., Ao, D., Archilli, F., Arnaud, K., Artamonov, A., Artuso, M., Ashby, J., Aslanides, E., Atzeni, M., Audurier, B., Rocha, D. Ayres, Perea, I. B Bachiller, Bachmann, S., Bachmayer, M., Back, J. J., Bailly-reyre, A., Rodriguez, P. Baladron, Balagura, V., Balbi, G., Baldini, W., Balla, A., Baltazar, M., Band, H., Leite, J. Baptista de Souza, Barbetti, M., Barclay, P., Barlow, R. J., Barsuk, S., Barter, W., Bartolini, M., Baryshnikov, F., Basels, J. M., Bassi, G., Baszczyk, M., Lopes, J. C. Batista, Batsukh, B., Battig, A., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I. B., Beigbeder-Beau, C., Beiter, A., Belin, S., Bellee, V., Belous, K., Belov, I., Belyaev, I., Benane, G., Bencivenni, G., Benettoni, M., Ben-Haim, E., Berezhnoy, A., Bernard, F., Bernet, R., Andres, S. Bernet, Berninghoff, D., Bernstein, H. C., Bertella, C., Bertolin, A., Betancourt, C., Betti, F., Bezshyiko, Ia., Bezshyyko, O., Bhasin, S., Bhom, J., Bian, L., Bieker, M. S., Biesuz, N. V., Billoir, P., Biolchini, A., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Blago, M. P., Blake, T., Blanc, F., Blank, J. E., Blusk, S., Bobulska, D., Bochin, B., Boelhauve, J. A., Garcia, O. Boente, Boettcher, T., Bogdanova, G., Boiaryntseva, I., Boldyrev, A., Bolognani, C. S., Bolzonella, R., Bondar, N., Booth, M. J., Borgato, F., Borghi, S., Borsato, M., Borsuk, J. T., Boterenbrood, H., Bouchiba, S. A., Bowcock, T. J. V., Boyaryntsev, A., Boyer, A., Bozzi, C., Bradley, M. J., Braun, S., Rodriguez, A. Brea, Bregliozzi, G., Bridges, K., Briere, M. M. J., Brock, M., Brodski, M., Brodzicka, J., Gonzalo, A. Brossa, Brown, C., Brown, J., Brummitt, A. J., Brundu, D., Brunetti, L., Buda, L., Buonaura, A., Buonincontri, L., Burke, A. T., Burmistrov, L., Burr, C., Bursche, A., Butkevich, A., Butter, J. S., Buytaert, J., Byczynski, W., Cachemiche, J. P., Cadeddu, S., Cai, H., Caillet, A., Calabrese, R., Calefice, L., Calegari, D., Cali, S., Calvi, M., Gomez, M. Calvo, Campana, P., Perez, D. H. Campora, Quezada, A. F. Campoverde, Canfer, S., Capelli, S., Capriotti, L., Carassiti, V., Carbone, A., Cardinale, R., Cardini, A., Carletti, M., Carniti, P., Carroll, J., Carus, L., Vidal, A. Casais, Caspary, R., Casse, G., Cattaneo, M., Cavallero, G., Cavallini, V., Ceelie, L., Celani, S., Cerasoli, J., Cervenkov, D., Cesare, S., Chadaj, B., Chadwick, A. J., Chahrour, I., Chanal, H., Chapman, M. G., Charles, M., Charpentier, Ph., Chaumat, V. J., Barajas, C. A. Chavez, Chefdeville, M., Chen, C., Chen, S., Chernov, A., Chernov, E., Chernyshenko, S., Chiozzi, S., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Cicala, M. F., Vidal, X. Cid, Ciezarek, G., Cifra, P., Citterio, M., Ciullo, G., Clark, K., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Cobbledick, J. L., Coco, V., Coelli, S., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Congedo, L., Conti, N., Contu, A., Cooke, N., Corredoira, I., Corti, G., Ramusino, A. Cotta, Couturier, B., Cowan, G. A., Craik, D. C., Torres, M. Cruz, Currie, R., Da Silva, C. L., Dadabaev, S., Dai, L., Dai, X., Dall'Occo, E., Dalseno, J., D'Ambrosio, C., Damen, A., Daniel, J., Danilina, A., d'Argent, P., Daudon, F., Davies, J. E., Davis, A., Davis, J., Francisco, O. De Aguiar, De Benedetti, F., de Boer, J., De Bruyn, K., De Capua, S., De Cian, M., Da Graca, U. De Freitas Carneiro, De Lucia, E., De Miranda, J. M., de Oliveira, R., De Paula, L., De Roo, K., De Serio, M., De Simone, D., De Simone, P., De Vellis, F., de Vries, J. A., De Wit, E., Dean, C. T., Debernardis, F., Decamp, D., Deckenhoff, M., Dedu, V., Del Buono, L., Delaney, B., Dembinski, H. -P., Denis, C., Denysenko, V., Deschamps, O., Dettori, F., Dey, B., Di Bari, D., Di Nezza, P., Diachkov, I., Didenko, S., Maronas, L. Dieste, Dijkstra, H., Ding, S., Dobishuk, V., Doets, M., Doherty, F., Dolmatov, A., Domke, M., Dong, C., Donohoe, A. M., Dordei, F., Dorosz, P., Reis, A. C. dos, Douglas, L., Downes, A. G., Duarte, O., Duda, P., Dudek, M. W., Dufour, L., Duk, V., Dumps, R., Durante, P., Duras, M. M., Durham, J. M., Dutta, D., Duval, P. Y., Dziewiecki, M., Dziurda, A., Dzyuba, A., Easo, S., Egede, U., Egorychev, V., Orro, C. Eirea, Eisenhardt, S., Ejopu, E., Ekelhof, R., Ek-In, S., Eklund, L., Elashri, M. E, Ellbracht, J., Elvin, A., Ely, S., Ene, A., Epple, E., Escher, S., Eschle, J., Esen, S., Evans, T., Fabiano, F., Falcao, L. N., Fan, Y., Fang, B., Fantini, L., Faria, M., Farry, S., Fazzini, D., Felkowski, L. F, Feo, M., Declara, P. Fernandez, Gomez, M. Fernandez, Fernez, A. D., Ferrari, F., Ferreira, R., Lopes, L. Ferreira, Rodrigues, F. Ferreira, Sole, S. Ferreres, Ferrillo, M., Ferro-Luzzi, M., Filippov, S., Fini, R. A., Fiorini, M., Firlej, M., Fischer, K. M., Fitzgerald, D. S., Fitzpatrick, C., Fiutowski, T., Fleuret, F., Flores, L., Fontana, M., Fontanelli, F., Forty, R., Foulds-Holt, D., Fournier, C., Lima, V. Franco, Sevilla, M. Franco, Frank, M., Franzoso, E., Frau, G., Freestone, J., Frei, C., Frei, R., Frelier, J., Friday, D. A., Frontini, L. F, Fu, J., Fuehring, Q., Fulghesu, T., Fuzipeg, C., Gabriel, E., Galati, G., Galati, M. D., Galka, M., Torreira, A. Gallas, Galli, D., Gallorini, S., Gambetta, S., Gan, Y., Gandelman, M., Gandini, P., Gao, R., Gao, Y., Garau, M., Martin, L. M. Garcia, Moreno, P. Garcia, Pardiñas, J. García, Plana, B. Garcia, Rosales, F. A. Garcia, Garrido, L., Garroum, N., Garsed, P. J., Gascon, D., Gaspar, C., Gasq, C., Gatta, M., Gavardi, L., Gebolis, P. M., Geertsema, R. E., Gerick, D., Gerken, L. L., Germann, D., Gersabeck, E., Gersabeck, M., Gershon, T., Getz, S. A., Giambastiani, L., Gibson, V., Giemza, H. K., Gilman, A. L., Giovannetti, M., Gioventù, A., Girard, O. G., Gironell, P. Gironella, Giugliano, C., Giza, M. A., Gizdov, K., Gkougkousis, E. L., Gligorov, V. V., Göbel, C., Golinka-Bezshyyko, L., Golobardes, E., Golubkov, D., Golutvin, A., Gomes, A., Fernandez, S. Gomez, Abrantes, F. Goncalves, Goncerz, M., Gong, G., Gorelov, I. V., Gotti, C., Grabowski, J. P., Grammatico, T., Cardoso, L. A. Granado, Grant, F., Graugés, E., Graverini, E., Graziani, G., Grecu, A. T., Greeven, L. M., Greim, R., Grieser, N. A., Grillo, L., Gromov, S., Gromov, V., Grub, N., Cazon, B. R. Gruberg, Grynyov, B., Gu, C., Guarise, M., Guerin, S., Guittiere, M., Günther, P. A., Gushchin, E., Guth, A., Guz, Y., Gys, T., Hachon, F., Hadavizadeh, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haimberger, J., Haines, S. C., Halewood-leagas, T., Halvorsen, M. M., Hamilton, P. M., Hammerich, J., Hamrat, S., Han, Q., Han, X., Hansen, E. B., Hansmann-Menzemer, S., Hao, L., Harnew, N., Harrison, T., Hasse, C., Hatch, M., He, J., Heijhoff, K., Hemmer, F. H, Henderson, C., Henderson, R. D. L., Hennequin, A. M., Hennessy, K., Henry, L., Herd, J., Herold, T., Heuel, J., Hicheur, A., Hill, D., Hilton, M., Hoft, G. T., Hollitt, S. E., Hopchev, P. H., Hornberger, O., Horswill, J., Hou, R., Hou, Y., Hu, J., Hu, W., Hu, X., Huang, W., Huang, X., Hulsbergen, W., Hummel, S., Hunter, R. J., Hushchyn, M., Hutanu, O. E., Hutchcroft, D., Hynds, D., Ibis, P., Idzik, M., Ilin, D., Ilten, P., Inglessi, A., Iniukhin, A., Insa, C., Ishteev, A., Ivshin, K., Jacobsson, R., Jage, H., Elles, S. J. Jaimes, Jakobsen, S., Jamet, O., Jans, E., Jashal, B. K., Jaspers, M., Jawahery, A., Jevaud, M., Jevtic, V., Jiang, E., Jiang, X., Jiang, Y., John, D., John, M., Johnson, D., Jones, C. R., Jones, T. P., Jost, B., Jurik, N., Juszczak, I., Kandybei, S., Kang, Y., Karacson, M., Kariuki, J. M., Karpenkov, D., Karpinski, W., Karpov, M., Kaufmann, K., Kautz, J. W., Kayzel, F., Keizer, F., Keller, D. M., Kenzie, M., Ketel, T., Khanji, B., Kharisova, A., Kholodenko, S., Khreich, G., Kirn, T., Kirsebom, V. S., Kitouni, O., Klaver, S., Kleijne, N., Klimaszewski, K., Kmiec, M. R., Kok, H., Koliiev, S., Kolk, L., Kondybayeva, A., Konoplyannikov, A., Kopciewicz, P., Kopecna, R., Koppenburg, P., Korolev, M., Kos, J., Kostiuk, I., Kot, O., Kotriakhova, S., Kozachuk, A., Kozlov, V. S., Kraan, M., Kravchenko, P., Kravchuk, L., Krawczyk, R. D., Kreps, M., Kretzschmar, S., Krokovny, P., Krupa, W., Krzemien, W., Kubat, J., Kubis, S., Kucewicz, W., Kucharczyk, M., Kudryavtsev, V., Kuhlman, A., Kuilman, W. C., Kulikova, E. K, Kuonen, A. K., Kupfer, N., Kupsc, A., Kvaratskheliya, T., Lacarrere, D., Lafferty, G., Lai, A., Lampis, A., Lancierini, D., Gomez, C. Landesa, Lane, J. J., Lane, R., Langenbruch, C., Langer, J., Langstaff, M., Lantwin, O., Latham, T., Lazzari, F., Lazzaroni, M., Dortz, O. Le, Gac, R. Le, Lee, S. H., Lefèvre, R., Leflat, A., Legotin, S., Lemaitre, F., Lenisa, P., Leroy, O., Lesiak, T., Leverington, B., Li, A., Li, H., Li, K., Li, P., Li, P. -R., Li, S., Li, T., Li, Y., Li, Z., Liang, X., Lieunard, B., Lin, C., Lin, T., Lindner, R., Lisovskyi, V., Litvinov, R., Liu, G., Liu, H., Liu, Q., Liu, S., Salvia, A. Lobo, Loi, A., Lollini, R., Castro, J. Lomba, Longstaff, I., Lopes, J. H., Huertas, A. Lopez, Soliño, S. López, Louis, D., Lovell, G. H., Loveridge, P., Lowe, A. D., Lu, Y., Lucarelli, C., Lucchesi, D., Luchuk, S., Martinez, M. Lucio, Lukashenko, V., Lukianov, A., Luo, H., Luo, Y., Lupato, A., Luppi, E., Lupton, O., Lusiani, A., Lutz, L. F., Lynch, K., Lyu, X. -R., Ma, R., Maccolini, S., Machefert, F., Maciuc, F., Mackay, I., Macko, V., Mackowiak, P., Maddrell-Mander, S., Mohan, L. R. Madhan, Maevskiy, A., Magne, M., Maisuzenko, D., Majewski, M. W., Malaguti, R., Malczewski, J. J., Malde, S., Malecki, B., Malinin, A., Malkinski, K., Maltsev, T., Manca, G., Mancinelli, G., Mancuso, C., Escalero, R. Manera, Manuzzi, D., Manzari, C. A., Marangotto, D., Marchand, J. F., Marconi, U., Mariani, S., Benito, C. Marin, Marks, J., Marshall, A. M., Marshall, P. J., Martelli, G., Martellotti, G., Martinazzoli, L., Martinelli, M., Santos, D. Martinez, Vidal, F. Martinez, Masic, B., Massafferri, A., Materok, M., Matev, R., Mathad, A., Mathe, Z., Matiunin, V., Matteuzzi, C., Mattioli, K. R., Mauri, A., Maurice, E., Mauricio, J., de Cos, J. Mazorra, Mazurek, M., McCann, M., Mcconnell, L., McGrath, T. H., McHugh, N. T., McNab, A., McNulty, R., Mead, J. V., Meadows, B., Meier, G., Meier-villardita, L., Melnychuk, D., Meloni, S., Merk, M., Merli, A., Meunier, J. L., Garcia, L. Meyer, Miao, D., Mikhasenko, M., Milanes, D. A., Millard, E., Miller, G., Milovanovic, M., Minard, M. -N., Minotti, A., Minutoli, S., Miralles, T., Mitchell, S. E., Mitreska, B., Mittelstaedt, T., Mitzel, D. S., Mödden, A., Modenese, L., Mogini, A., Mohammed, R. A., Moise, R. D., Mokhnenko, S., Mombächer, T., Monk, M., Monroy, I. A., Monteil, S., Monti, M., Morandin, M., Morello, G., Morello, M. J., Morgenthaler, M. P., Moron, J., Morris, A. B., Morris, A. G., Mountain, R., Mu, H., Muhammad, E., Muheim, F., Mulder, M., Muley, S., Müller, D., Müller, K., Munneke, B., Murphy, C. H., Murray, D., Murta, R., Muzzetto, P., Naik, P., Naik, S. A., Nakada, T., Nandakumar, R., Nanut, T., Nasteva, I., Nazarov, E., Needham, M., Neri, I., Neri, N., Neubert, S., Neufeld, N., Neustroev, P., Newcombe, R., Trung, T. Nguyen, Nicolini, J., Nicotra, D., Niel, E. M., Nieswand, S., Nikitin, N., Nolte, N. S., Normand, C., Fernandez, J. Novoa, Nowak, G. N, Nunez, C., O'Bannon, T., Oblakowska-Mucha, A., Obraztsov, V., O'Dell, J., Oeser, T., Okamura, S., Oldeman, R., Oliva, F., Olive, P., Onderwater, C. J. G., O'Neil, R. H., Orlov, V., Goicochea, J. M. Otalora, Ovsiannikova, T., Owen, P., Oyanguren, A., Ozcelik, O., Padeken, K. O., Pagare, B., Pais, P. R., Pajero, T., Palano, A., Palutan, M., Pan, Y., Panshin, G., Paoletti, E., Paolucci, L., Papanestis, A., Pappagallo, M., Pappalardo, L. L., Pappenheimer, C., Parker, W., Parkes, C., Pasquali, L., Passalacqua, B., Passaleva, G., Pastore, A., Patel, M., Patrignani, C., Pavlenko, D., Pawley, C. J., Pearce, A., Regales, M. D. P. Peco, Pellegrino, A., Peltier, F., Altarelli, M. Pepe, Perazzini, S., Pereima, D., Castro, A. Pereiro, Perret, P., Perro, A., Perry, M., Pessina, G., Petridis, K., Petrolini, A., Petrucci, S., Petruzzo, M., Pham, H., Philippov, A., Piandani, R., Pica, L., Olloqui, E. Picatoste, Piccini, M., Piedigrossi, D., Pietrzyk, B., Pietrzyk, G., Pili, M., Pillet, N., Pilorz, E. M., Pinci, D., Pisani, F., Pizzichemi, M., Placinta, V., Plews, J., Casasus, M. Plo, Polci, F., Lener, M. Poli, Poluektov, A., Polukhina, N., Polyakov, I., Polyakov, V., Polycarpo, E., Pomery, G. J., Ponce, S., Pons, X., Poplawski, K., Popov, D., Poslavskii, S., Prasanth, K., Pratt, D., Promberger, L., Prouve, C., Pugatch, V., Puill, V., Punzi, G., Qi, H. R., Qian, W., Qin, N., Qu, S., Quagliani, R., Raab, N. V., Rachwal, B., Rademacker, J. H., Rajagopalan, R., Rama, M., Ramaherison, J. J., Pernas, M. Ramos, Rangel, M. S., Ratnikov, F., Raven, G., De Miguel, M. Rebollo, Redi, F., Reich, J., Reiss, F., Alepuz, C. Remon, Ren, Z., Resmi, P. K., Rethore, F., Reynet, D., Ribatti, R., Ricci, A. M., Ricciardi, S., Richards, D. S., Richardson, K., Richardson-Slipper, M., Riedinger, J., Rinnert, K., Robbe, P., Robertson, G., Rochet, J., Rodrigues, A. B., Rodrigues, E., Fernandez, E. Rodriguez, Lopez, J. A. Rodriguez, Perez, P. Rodriguez, Rodriguez, E. Rodriguez, Roeland, E., Rolf, D. L., Rollings, A., Roloff, P., Romanovskiy, V., Lamas, M. Romero, Vidal, A. Romero, Rosier, P., Roth, J. D., Rotondo, M., Rovekamp, J., Roy, L., Rudnyckyj, F., Rudolph, M. S., Ruf, T., Fernandez, R. A. Ruiz, Vidal, J. Ruiz, Ryzhikov, A., Ryzka, J., Silva, J. J. Saborido, Sagidova, N., Sahoo, N., Saitta, B., Salomoni, M., Gras, C. Sanchez, Sanders, F., Sanderswood, I., Santacesaria, R., Rios, C. Santamarina, Santimaria, M., Santovetti, E., Saputi, A., Saranin, D., Sarpis, G., Sarpis, M., Sarti, A., Satriano, C., Satta, A., Saur, M., Saussac, A., Savrina, D., Sazak, H., Sborzacchi, F., Smead, L. G. Scantlebury, Scarabotto, A., Schael, S., Scherl, S., Schiller, M., Schimmel, A., Schindler, H., Schipper, J. D., Schmeitz, R., Schmelling, M., Schmidt, B., Schmitt, S., Schneider, O., Schneider, T., Schopper, A., Schubiger, M., Schulte, S., Schune, M. H., Schwemmer, R., Sciascia, B., Sciuccati, A., Sellam, S., Semennikov, A., Soares, M. Senghi, Sergi, A., Serra, N., Sestak, J., Sestini, L., Seuthe, A., Seyfert, P., Shang, Y., Shangase, D. M., Shapkin, M., Shchemerov, I., Shchutska, L., Shears, T., Shekhtman, L., Shen, Z., Sheng, S., Sherman, M. s, Shevchenko, V., Shi, B., Shields, E. B., Shimizu, Y., Shmanin, E., Shorkin, R., Shupperd, J. D., Siddi, B. G., Siebig, S., Sigmund, D., Sigurdsson, S., Coutinho, R. Silva, Simi, G., Simone, S., Singla, M., Skidmore, N., Skuza, R., Skwarnicki, T., Slater, M. W., Slattery, K., Slazyk, I., Smallwood, J. C., Smeaton, J. G., Smith, E., Smith, K., Smith, M., Smith, N. A., Snoch, A., Lavra, L. Soares, Socha, J-L., Sokoloff, M. D., Soler, F. J. P., Solomin, A., Solovev, A., Solovyev, I., Song, R., De Almeida, F. L. Souza, De Paula, B. Souza, Spaan, B., Norella, E. Spadaro, Spedicato, E., Spiridenkov, E., Spradlin, P., Squerzanti, S., Sriskaran, V., Stagni, F., Stahl, M., Stahl, S., Stanislaus, S., Steffens, E., Stein, E. N., Steinkamp, O., Stenyakin, O., Stevens, H., Stone, S., Stramaglia, M. E., Strekalina, D., Su, Y. S, Suljik, F., Sun, J., Sun, L., Sun, Y., Svihra, P., Swallow, P. N., Swientek, K., Swientek, S., Szabelski, A., Szumlak, T., Szymanski, M., Tagliente, G, Tan, Y., Taneja, S., Tat, M. D., Quere, M. Taurigna, Terentev, A., Terront, D. F., Teubert, F., Thomas, E., Thompson, D. J. D., Thomson, K. A., Tilquin, H., Tisserand, V., T'Jampens, S., Tobin, M., Tomassetti, L., Tonani, G., Tong, X., Topp-Joergensen, S., Machado, D. Torres, Tou, D. Y., Trilov, S. M., Trippl, C., Tuci, G., Tuning, N., Ukleja, A., Unverzagt, D. J., Usachov, A., Ustyuzhanin, A., Uwer, U., Vagner, A., Vagnoni, V., Valassi, A., Valat, S., Valenti, G., Canudas, N. Valls, van Beuzekom, M., Van De Kraats, P. W., van der Heijden, B., Van Dijk, M., van Dongen, J., Van Hecke, H., van Herwijnen, E., Van Hulse, C. B., Van Nieuwland, L., van Overbeek, M., Van Stenis, M., van Veghel, M., Vandaele, R., Gomez, R. Vazquez, Regueiro, P. Vazquez, Sierra, C. Vázquez, Vecchi, S., Veldt, L., Velthuis, J. J., Veltri, M., Venkateswaran, A., Verkooijnen, H., Veronesi, M., Vesterinen, M., Barbosa, J. V. Viana, Vieira, D., Diaz, M. Vieites, Viel, K. J., Vilasis-Cardona, X., Figueras, E. Vilella, Villa, A., Vincent, P., Vink, W., Vitkovskiy, A., Volkov, V., Volle, F. C., Bruch, D. vom, Voneki, B., Vorbach, O., Vorobyev, A., Vorobyev, V., Voropaev, N., Vos, K., Vouters, G., Vrahas, C., Walet, W., Walsh, J., Walton, E. J., Wan, G., Wang, C., Wang, G., Wang, J., Wang, M., Wang, R., Wang, X., Wang, Y., Wang, Z., Ward, J. A., Warda, K., Watson, N. K., Websdale, D., Webster, J., Wei, Y., Westhenry, B. D. C., White, D. J., Whitehead, M., Wieczorek, D., Wiederhold, A. R., Wiedner, D., Wilkinson, G., Wilkinson, M. K., Williams, I., Williams, M., Williams, M. R. J., Williams, R., Wilson, F. F., Wimberley, J., Windelband, B., Wislicki, W., Witek, M., Witola, L., Wlochal, M., Wong, C. P., Wormald, M., Wormser, G., Wotton, S. A., Wraight, K., Wu, H., Wu, J., Wyllie, K., Xiang, Z., Xie, Y., Xu, A., Xu, J., Xu, L., Xu, M., Xu, Q., Xu, Z., Yang, D., Yang, S., Yang, X., Yang, Y., Yang, Z., Yeomans, L. E., Yeroshenko, V., Yeung, H., Yin, H., Yu, J., Yuan, X., Zaffaroni, E., Zavertyaev, M., Zdybal, M., Zenaiev, O., Zeng, M., Zhang, C., Zhang, D., Zhang, L., Zhang, S., Zhang, Y., Zhao, Y., Zharkova, A., Zhelezov, A., Zheng, Y., Zhou, T., Zhou, X., Zhou, Y., Zhovkovska, V., Zhu, X., Zhu, Z., Zhukov, V., Zivkovic, V., Zou, Q., Zucchelli, S., Zuliani, D., Zunica, G., and Zvyagintsev, S.
Subjects: High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract: The LHCb upgrade represents a major change of the experiment. The detectors have been almost completely renewed to allow running at an instantaneous luminosity five times larger than that of the previous running periods. Readout of all detectors into an all-software trigger is central to the new design, facilitating the reconstruction of events at the maximum LHC interaction rate, and their selection in real time. The experiment's tracking system has been completely upgraded with a new pixel vertex detector, a silicon tracker upstream of the dipole magnet and three scintillating fibre tracking stations downstream of the magnet. The whole photon detection system of the RICH detectors has been renewed and the readout electronics of the calorimeter and muon systems have been fully overhauled. The first stage of the all-software trigger is implemented on a GPU farm. The output of the trigger provides a combination of totally reconstructed physics objects, such as tracks and vertices, ready for final analysis, and of entire events which need further offline reprocessing. This scheme required a complete revision of the computing model and rewriting of the experiment's software., Comment: All figures and tables, along with any supplementary material and additional information, are available at http://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-DP-2022-002.html (LHCb public pages)
Published: 2023
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5. Interleukin (IL)-1/IL-6-Inhibitor–Associated Drug Reaction With Eosinophilia and Systemic Symptoms (DReSS) in Systemic Inflammatory Illnesses

Author: Aamir, R., Abulaban, K., Adams, A., Lapsia, C. Aguiar, Akinsete, A., Akoghlanian, S., Al Manaa, M., AlBijadi, A., Allenspach, E., Almutairi, A., Alperin, R., Amarilyo, G., Ambler, W., Amoruso, M., Angeles-Han, S., Ardoin, S., Armendariz, S., Asfaw, L., Aviran Dagan, N., Bacha, C., Balboni, I., Balevic, S., Ballinger, S., Baluta, S., Barillas-Arias, L., Basiaga, M., Baszis, K., Baxter, S., Becker, M., Begezda, A., Behrens, E., Beil, E., Benseler, S., Bermudez-Santiago, L., Bernal, W., Bigley, T., Bingham, C., Binstadt, B., Black, C., Blackmon, B., Blakley, M., Bohnsack, J., Boneparth, A., Bradfield, H., Bridges, J., Brooks, E., Brothers, M., Brunner, H., Buckley, L., Buckley, M., Bukulmez, H., Bullock, D., Canna, S., Cannon, L., Canny, S., Cartwright, V., Cassidy, E., Castro, D., Chalom, E., Chang, J., Chang, M., Chang-Hoftman, A., Chen, A., Chiraseveenuprapund, P., Ciaglia, K., Co, D., Cohen, E., Collinge, J., Conlon, H., Connor, R., Cook, K., Cooper, A., Cooper, J., Corbin, K., Correll, C., Cron, R., Curry, M., Dalrymple, A., Datyner, E., Davis, T., De Ranieri, D., Dean, J., DeCoste, C., Dedeoglu, F., DeGuzman, M., Delnay, N., DeSantis, E., Devine, R., Dhalla, M., Dhanrajani, A., Dissanayake, D., Dizon, B., Drapeau, N., Drew, J., Driest, K., Du, Q., Duncan, E., Dunnock, K., Durkee, D., Dvergsten, J., Eberhard, A., Ede, K., Edelheit, B., Edens, C., El Tal, T., Elder, M., Elzaki, Y., Fadrhonc, S., Failing, C., Fair, D., Favier, L., Feldman, B., Fennell, J., Ferguson, P., Ferguson, I., Figueroa, C., Flanagan, E., Fogel, L., Fox, E., Fox, M., Franklin, L., Fuhlbrigge, R., Fuller, J., Furey, M., Futch-West, T., Gagne, S., Gennaro, V., Gerstbacher, D., Gilbert, M., Gironella, A., Glaser, D., Goh, I., Goldsmith, D., Gorry, S., Goswami, N., Gottlieb, B., Graham, T., Grevich, S., Griffin, T., Grim, A., Grom, A., Guevara, M., Hahn, T., Halyabar, O., Hamda Natur, M., Hammelev, E., Hammond, T., Harel, L., Harris, J., Harry, O., Hausmann, J., Hay, A., Hays, K., Hayward, K., Henderson, L., Henrickson, M., Hersh, A., Hickey, K., Hiraki, L., Hiskey, M., Hobday, P., Hoffart, C., Holland, M., Hollander, M., Hong, S., Horton, D., Horwitz, M., Hsu, J., Huber, A., Huberts, A., Huggins, J., Huie, L., Hui-Yuen, J., Ibarra, M., Imlay, A., Imundo, L., Inman, C., Jackson, A., James, K., Janow, G., Jared, S., Jiang, Y., Johnson, L., Johnson, N., Jones, J., Kafisheh, D., Kahn, P., Kaidar, K., Kasinathan, S., Kaur, R., Kessler, E., Kienzle, B., Kim, S., Kimura, Y., Kingsbury, D., Kitcharoensakkul, M., Klausmeier, T., Klein, K., Klein-Gitelman, M., Knight, A., Kovalick, L., Kramer, S., Kremer, C., Kudas, O., LaFlam, T., Lang, B., Lapidus, S., Lapin, B., Lasky, A., Lawler, C., Lawson, E., Laxer, R., Lee, P., Lee, T., Lee, A., Leisinger, E., Lentini, L., Lerman, M., Levinsky, Y., Levy, D., Li, S., Lieberman, S., Lim, L., Limenis, E., Lin, C., Ling, N., Lionetti, G., Livny, R., Lloyd, M., Lo, M., Long, A., Lopez-Peña, M., Lovell, D., Luca, N., Lvovich, S., Lytch, A., Ma, M., Machado, A., MacMahon, J., Madison, J., Mannion, M., Manos, C., Mansfield, L., Marston, B., Mason, T., Matchett, D., McAllister, L., McBrearty, K., McColl, J., McCurdy, D., McDaniels, K., McDonald, J., Meidan, E., Mellins, E., Mian, Z., Miettunen, P., Miller, M., Milojevic, D., Mitacek, R., Modica, R., Mohan, S., Moore, T., Moore, K., Moorthy, L., Moreno, J., Morgan, E., Moyer, A., Murante, B., Murphy, A., Muscal, E., Mwizerwa, O., Najafi, A., Nanda, K., Nasah, N., Nassi, L., Nativ, S., Natter, M., Nearanz, K., Neely, J., Newhall, L., Nguyen, A., Nigrovic, P., Nocton, J., Nolan, B., Nowicki, K., Oakes, R., Oberle, E., Ogbonnaya-Whittesley, S., Ogbu, E., Oliver, M., Olveda, R., Onel, K., Orandi, A., Padam, J., Paller, A., Pan, N., Pandya, J., Panupattanapong, S., Toledano, A. Pappo, Parsons, A., Patel, J., Patel, P., Patrick, A., Patrizi, S., Paul, S., Perfetto, J., Perron, M., Peskin, M., Ponder, L., Pooni, R., Prahalad, S., Puplava, B., Quinlan-Waters, M., Rabinovich, C., Rafko, J., Rahimi, H., Rampone, K., Ramsey, S., Randell, R., Ray, L., Reed, A., Reid, H., Reiff, D., Richins, S., Riebschleger, M., Rife, E., Riordan, M., Riskalla, M., Robinson, A., Robinson, L., Rodgers, L., Rodriquez, M., Rogers, D., Ronis, T., Rosado, A., Rosenkranz, M., Rosenwasser, N., Rothermel, H., Rothman, D., Rothschild, E., Roth-Wojcicki, E., Rouster-Stevens, K., Rubinstein, T., Rupp, J., Ruth, N., Sabbagh, S., Sadun, R., Santiago, L., Saper, V., Sarkissian, A., Scalzi, L., Schahn, J., Schikler, K., Schlefman, A., Schmeling, H., Schmitt, E., Schneider, R., Schulert, G., Schultz, K., Schutt, C., Seper, C., Sheets, R., Shehab, A., Shenoi, S., Sherman, M., Shirley, J., Shishov, M., Siegel, D., Singer, N., Sivaraman, V., Sloan, E., Smith, C., Smith, J., Smitherman, E., Soep, J., Son, Mary B., Sosna, D., Spencer, C., Spiegel, L., Spitznagle, J., Srinivasalu, H., Stapp, H., Steigerwald, K., Stephens, A., Sterba Rakovchik, Y., Stern, S., Stevens, B., Stevenson, R., Stewart, K., Stewart, W., Stingl, C., Stoll, M., Stringer, E., Sule, S., Sullivan, J., Sundel, R., Sutter, M., Swaffar, C., Swayne, N., Syed, R., Symington, T., Syverson, G., Szymanski, A., Taber, S., Tal, R., Tambralli, A., Taneja, A., Tanner, T., Tarvin, S., Tate, L., Taxter, A., Taylor, J., Tesher, M., Thakurdeen, T., Theisen, A., Thomas, B., Thomas, L., Thomas, N., Ting, T., Todd, C., Toib, D., Torok, K., Tory, H., Toth, M., Tse, S., Tsin, C., Twachtman-Bassett, J., Twilt, M., Valcarcel, T., Valdovinos, R., Vallee, A., Van Mater, H., Vandenbergen, S., Vannoy, L., Varghese, C., Vasquez, N., Vega-Fernandez, P., Velez, J., Verbsky, J., Verstegen, R., von Scheven, E., Vora, S., Wagner-Weiner, L., Wahezi, D., Waite, H., Walker, B., Walters, H., Waterfield, M., Waters, A., Weiser, P., Weiss, P., Weiss, J., Wershba, E., Westheuser, V., White, A., Widrick, K., Williams, C., Wong, S., Woolnough, L., Wright, T., Wu, E., Yalcindag, A., Yasin, S., Yeung, R., Yomogida, K., Zeft, A., Zhang, Y., Zhao, Y., Zhu, A., Saper, Vivian E., Tian, Lu, Verstegen, Ruud H.J., Conrad, Carol K., Cidon, Michal, Hopper, Rachel K., Kuo, Christin S., Osoegawa, Kazutoyo, Baszis, Kevin, Bingham, Catherine A., Ferguson, Ian, Hahn, Timothy, Horne, Annacarin, Isupova, Eugenia A., Jones, Jordan T., Kasapcopur, Özgür, Klein-Gitelman, Marisa S., Kostik, Mikhail M., Ozen, Seza, Phadke, Omkar, Prahalad, Sampath, Randell, Rachel L., Sener, Seher, Stingl, Cory, Abdul-Aziz, Rabheh, Akoghlanian, Shoghik, Al Julandani, Dalila, Alvarez, Marcela B., Bader-Meunier, Brigitte, Balay-Dustrude, Erin E., Balboni, Imelda, Baxter, Sarah K., Berard, Roberta A., Bhattad, Sagar, Bolaria, Roxana, Boneparth, Alexis, Cassidy, Elaine A., Co, Dominic O., Collins, Kathleen P., Dancey, Paul, Dickinson, Aileen M., Edelheit, Barbara S., Espada, Graciela, Flanagan, Elaine R., Imundo, Lisa F., Jindal, Ankur K., Kim, Hyoun-Ah, Klaus, Günter, Lake, Carol, Lapin, W. Blaine, Lawson, Erica F., Marmor, Itay, Mombourquette, Joy, Ogunjimi, Benson, Olveda, Rebecca, Ombrello, Michael J., Onel, Karen, Poholek, Catherine, Ramanan, Athimalaipet V., Ravelli, Angelo, Reinhardt, Adam, Robinson, Amanda D., Rouster-Stevens, Kelly, Saad, Nadine, Schneider, Rayfel, Selmanovic, Velma, Sefic Pasic, Irmina, Shenoi, Susan, Shilo, Natalie R., Soep, Jennifer B., Sura, Angeli, Taber, Sarah F., Tesher, Melissa, Tibaldi, Jessica, Torok, Kathryn S., Tsin, Cathy Mei, Vasquez-Canizares, Natalia, Villacis Nunez, Diana S., Way, Emily E., Whitehead, Benjamin, Zemel, Lawrence S., Sharma, Surbhi, Fernández-Viña, Marcelo A., and Mellins, Elizabeth D.
Published: 2024
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6. Residential Smart Ventilation: A Review

Author: Walker, IS, Guyot, G, Sherman, M, and Jordan, C
Published: 2021

7. The LHCb Upgrade I

Author: Ayres Rocha, D, Baptista de Souza Leite, J, Bediaga, I, Cruz Torres, M, De Freitas Carneiro Da Graca, U, De Miranda, J, dos Reis, A, Falcao, L, Gomes, A, Massafferri, A, Torres Machado, D, Amato, S, De Paula, L, Ferreira Rodrigues, F, Gandelman, M, Hicheur, A, Lopes, J, Meyer Garcia, L, Nasteva, I, Otalora Goicochea, J, Polycarpo, E, Rangel, M, Souza De Almeida, F, Souza De Paula, B, Dong, C, Gan, Y, Gong, G, Gu, C, Hu, X, Kang, Y, Li, A, Luo, Y, Mu, H, Qi, H, Qin, N, Qu, S, Ren, Z, Tan, Y, Tou, D, Wang, J, Wang, Z, Xu, L, Yang, D, Zeng, M, Zhang, L, Zhu, X, Batsukh, B, Chen, S, Jiang, X, Li, T, Li, Y, Liu, S, Lu, Y, Miao, D, Sheng, S, Tobin, M, Zou, Q, Dai, X, Gao, Y, Hu, W, Shang, Y, Shen, Z, Tong, X, Wan, G, Wei, Y, Xu, A, Yang, X, Yang, Z, Zhang, C, Zhang, S, Zhang, Y, Zhou, T, Ao, D, Campoverde Quezada, A, Fan, Y, Fu, J, Hao, L, He, J, Huang, W, Jiang, Y, Lin, C, Liu, H, Liu, Q, Lyu, X, Ma, R, Piandani, R, Popov, D, Qian, W, Shi, B, Su, Y, Tuci, G, Xiang, Z, Xu, J, Xu, Q, Xu, Z, Yang, S, Yang, Y, Zheng, Y, Zhou, X, Zhou, Y, Zhu, Z, Han, Q, Hou, R, Li, K, Li, S, Wang, G, Wang, Y, Wu, J, Xie, Y, Yin, H, Zhang, D, Bachiller Perea, I, Brunetti, L, Chefdeville, M, Decamp, D, Downes, A, Hou, Y, Lieunard, B, Marchand, J, Minard, M, Normand, C, Peltier, F, Pietrzyk, B, T'Jampens, S, Vouters, G, Achard, C, Afsharnia, H, Ajaltouni, Z, Chanal, H, Cogneras, E, Daniel, J, Daudon, F, Deschamps, O, Gasq, C, Hamrat, S, Insa, C, Lefevre, R, Magne, M, Miralles, T, Monteil, S, Perret, P, Pillet, N, Ramaherison, J, Sazak, H, Soares Lavra, L, Tisserand, V, Vandaele, R, Arnaud, K, Aslanides, E, Benane, G, Cachemiche, J, Cerasoli, J, Chen, C, Cogan, J, Dedu, V, Duval, P, Hachon, F, Jevaud, M, Le Gac, R, Leroy, O, Mancinelli, G, Olive, P, Poluektov, A, Rethore, F, vom Bruch, D, Amhis, Y, Baltazar, M, Barsuk, S, Beigbeder-Beau, C, Briere, M, Burmistrov, L, Chaumat, V, Duarte, O, Fang, B, Guittiere, M, Khreich, G, Machefert, F, Malkinski, K, Mancuso, C, Nguyen Trung, T, Nicolini, J, Pietrzyk, G, Puill, V, Reynet, D, Robbe, P, Rosier, P, Rudnyckyj, F, Saussac, A, Schune, M, Shimizu, Y, Socha, J, Taurigna Quere, M, Volle, F, Wormser, G, Yeroshenko, V, Zhovkovska, V, Audurier, B, Balagura, V, Boente Garcia, O, Fleuret, F, Garcia Rosales, F, Mattioli, K, Maurice, E, Agapopoulou, C, Amalric, R, Bailly-Reyre, A, Ben-Haim, E, Billoir, P, Charles, M, Del Buono, L, Fontana, M, Fulghesu, T, Garroum, N, Gligorov, V, Grammatico, T, Le Dortz, O, Meunier, J, Mogini, A, Polci, F, Scarabotto, A, Terront, D, Vincent, P, Basels, J, Carus, L, Escher, S, Guth, A, Heuel, J, Jage, H, Karpinski, W, Kirn, T, Kretzschmar, S, Langenbruch, C, Louis, D, Materok, M, Moise, R, Nieswand, S, Oeser, T, Sarpis, G, Schael, S, Schmitt, S, Wlochal, M, Zhukov, V, Albrecht, J, Battig, A, Becker, M, Bieker, M, Blank, J, Boelhauve, J, Calefice, L, Dall'Occo, E, De Vellis, F, Deckenhoff, M, Dembinski, H, Domke, M, Ekelhof, R, Ellbracht, J, Fuehring, Q, Gavardi, L, Gerken, L, Hollitt, S, Ibis, P, Jevtic, V, Khanji, B, Kolk, L, Langer, J, Lisovskyi, V, Maccolini, S, Mackowiak, P, Meier, G, Mitreska, B, Mitzel, D, Modden, A, Saur, M, Seuthe, A, Spaan, B, Stevens, H, Swientek, S, Warda, K, Wieczorek, D, Wiedner, D, Schmelling, M, Zavertyaev, M, Anjam, A, Bachmann, S, Berninghoff, D, Borsato, M, Caspary, R, Dziewiecki, M, Frau, G, Gerick, D, Gunther, P, Han, X, Hansmann-Menzemer, S, Herold, T, Hornberger, O, Hu, J, Hummel, S, Kopecna, R, Kubat, J, Kupfer, N, Leverington, B, Marks, J, Mittelstaedt, T, Morgenthaler, M, Muley, S, Promberger, L, Riedinger, J, Siebig, S, Sigmund, D, Skuza, R, Unverzagt, D, Uwer, U, Vorbach, O, Wang, C, Windelband, B, Witola, L, Zhao, Y, Zhelezov, A, Donohoe, A, Lynch, K, Mcconnell, L, Mcnulty, R, Raab, N, Congedo, L, D'Argent, P, De Serio, M, Debernardis, F, Fini, R, Galati, G, Palano, A, Pappagallo, M, Pastore, A, Simone, S, Tagliente, G, Balbi, G, Capriotti, L, Carbone, A, Ferrari, F, Galli, D, Manuzzi, D, Marconi, U, Patrignani, C, Perazzini, S, 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K., Kvaratskheliya T., Lantwin O., Leflat A., Legotin S., Luchuk S., Lukianov A., Maevskiy A., Maisuzenko D., Malinin A., Maltsev T., Matiunin V., Mokhnenko S., Nazarov E., Neustroev P., Nikitin N., Obraztsov V., Ovsiannikova T., Panshin G., Pavlenko D., Pereima D., Philippov A., Polukhina N., Polyakov V., Poslavskii S., Ratnikov F., Romanovskiy V., Ryzhikov A., Sagidova N., Saranin D., Savrina D., Semennikov A., Shapkin M., Shchemerov I., Shekhtman L., Shevchenko V., Shmanin E., Shorkin R., Solomin A., Solovev A., Solovyev I., Spiridenkov E., Stenyakin O., Strekalina D., Ustyuzhanin A., Vagner A., Volkov V., Vorobyev A., Vorobyev V., Voropaev N., Zharkova A., Zvyagintsev S., Alfonso Albero A., Garcia Moreno P., Garrido L., Gascon D., Gironella Gironell P., Gomez Fernandez S., Grauges E., Lobo Salvia A., Lopez Huertas A., Manera Escalero R., Marin Benito C., Mauricio J., Picatoste Olloqui E., Vazquez Gomez R., Adeva B., Baladron Rodriguez P., Belin S., Brea Rodriguez A., Brossa Gonzalo A., Casais Vidal A., Chobanova V., Cid Vidal X., Corredoira I., Dalseno J., Dieste Maronas L., Eirea Orro C., Fernandez Gomez M., Fernandez Prieto A., Gallas Torreira A., Garcia Plana B., Gioventu A., Landesa Gomez C., Lemos Cid E., Lomba Castro J., Lopez Solino S., Martinez Santos D., Mombacher T., Novoa Fernandez J., Pazos Alvarez A., Pereiro Castro A., Perez Trigo E., Plo Casasus M., Prouve C., Rodriguez Fernandez E., Rodriguez Rodriguez E., Romero Lamas M., Romero Vidal A., Ruiz Fernandez R. 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B., Brundu D., Cadeddu S., Cardini A., Contu A., Dettori F., Dordei F., Fabiano F., Garau M., Lai A., Lampis A., Litvinov R., Loi A., Manca G., Muzzetto P., Oldeman R., Ricci A. M., Saitta B., Sun J., Benettoni M., Bertolin A., Borgato F., Buonincontri L., Gallorini S., Giambastiani L., Lucchesi D., Modenese L., Morandin M., Sestini L., Simi G., Zuliani D., Bassi G., Bedeschi F., Kleijne N., Lazzari F., Lusiani A., Morello M. J., Pica L., Punzi G., Rama M., Ribatti R., Walsh J., Martellotti G., Pinci D., Santacesaria R., Sarti A., Satriano C., Archilli F., Santovetti E., Satta A., Aaij R., Akiba K., Band H., Biolchini A., Boterenbrood H., Butter J. S., Ceelie L., Damen A., De Roo K., De Wit E., Doets M., Ferreres Sole S., Gabriel E., Galati M. D., Geertsema R. E., Greeven L. M., Greim R., Gromov V., Heijhoff K., Hoft G. T., Hulsbergen W., Hynds D., Jans E., Jaspers M., John D., Kayzel F., Ketel T., Kok H., Koppenburg P., Kos J., Kostiuk I., Kraan M., Kuilman W. C., Lukashenko V., Mauri A., Merk M., Munneke B., Pellegrino A., Poplawski K., Roeland E., Rovekamp J., Sanchez Gras C., Sanders F., Schimmel A., Schipper J. D., Schmeitz R., Schubiger M., Snoch A., Tuning N., van Beuzekom M., Van De Kraats P. W., van der Heijden B., Van Nieuwland L., van Overbeek M., van Veghel M., Veldt L., Verkooijnen H., Veronesi M., Vink W., Vitkovskiy A., Walet W., Zivkovic V., Klaver S., Raven G., Senghi Soares M., Usachov A., van Dongen J., Firlej M., Fiutowski T., Idzik M., Kopciewicz P., Krupa W., Majewski M. W., Moron J., Oblakowska-Mucha A., Peco Regales M. D. P., Pilorz E. M., Rachwal B., Ryzka J., Swientek K., Szumlak T., Baszczyk M., Bhom J., Borsuk J. T., Brodzicka J., Chernov A., Chrzaszcz M., Dorosz P., Dudek M. W., Dziurda A., Giza M. A., Goncerz M., Juszczak I., Kucewicz W., Kucharczyk M., Lesiak T., Malczewski J. J., Malecki B., Prasanth K., Witek M., Zdybal M., Giemza H. K., Klimaszewski K., Kmiec M. R., Krzemien W., Melnychuk D., Szabelski A., Ukleja A., Wislicki W., Cojocariu L., Ene A., Grecu A. T., Hutanu O. E., Maciuc F., Placinta V., Andreianov A., Artamonov A., Baryshnikov F., Belous K., Belov I., Belyaev I., Berezhnoy A., Bochin B., Bogdanova G., Boldyrev A., Bondar N., Butkevich A., Chernov E., Chubykin A., Chulikov V., Dadabaev S., Danilina A., Diachkov I., Didenko S., Dolmatov A., Dzyuba A., Egorychev V., Filippov S., Getz S. A., Golubkov D., Golutvin A., Gorelov I. V., Gromov S., Gushchin E., Guz Y., Hushchyn M., Ilin D., Inglessi A., Iniukhin A., Ishteev A., Ivshin K., Karpenkov D., Karpov M., Kharisova A., Kholodenko S., Kondybayeva A., Konoplyannikov A., Korolev M., Kozachuk A., Kozlov V. S., Kravchenko P., Kravchuk L., Krokovny P., Kudryavtsev V., Kulikova E. K., Kvaratskheliya T., Lantwin O., Leflat A., Legotin S., Luchuk S., Lukianov A., Maevskiy A., Maisuzenko D., Malinin A., Maltsev T., Matiunin V., Mokhnenko S., Nazarov E., Neustroev P., Nikitin N., Obraztsov V., Ovsiannikova T., Panshin G., Pavlenko D., Pereima D., Philippov A., Polukhina N., Polyakov V., Poslavskii S., Ratnikov F., Romanovskiy V., Ryzhikov A., Sagidova N., Saranin D., Savrina D., Semennikov A., Shapkin M., Shchemerov I., Shekhtman L., Shevchenko V., Shmanin E., Shorkin R., Solomin A., Solovev A., Solovyev I., Spiridenkov E., Stenyakin O., Strekalina D., Ustyuzhanin A., Vagner A., Volkov V., Vorobyev A., Vorobyev V., Voropaev N., Zharkova A., Zvyagintsev S., Alfonso Albero A., Garcia Moreno P., Garrido L., Gascon D., Gironella Gironell P., Gomez Fernandez S., Grauges E., Lobo Salvia A., Lopez Huertas A., Manera Escalero R., Marin Benito C., Mauricio J., Picatoste Olloqui E., Vazquez Gomez R., Adeva B., Baladron Rodriguez P., Belin S., Brea Rodriguez A., Brossa Gonzalo A., Casais Vidal A., Chobanova V., Cid Vidal X., Corredoira I., Dalseno J., Dieste Maronas L., Eirea Orro C., Fernandez Gomez M., Fernandez Prieto A., Gallas Torreira A., Garcia Plana B., Gioventu A., Landesa Gomez C., Lemos Cid E., Lomba Castro J., Lopez Solino S., Martinez Santos D., Mombacher T., Novoa Fernandez J., Pazos Alvarez A., Pereiro Castro A., Perez Trigo E., Plo Casasus M., Prouve C., Rodriguez Fernandez E., Rodriguez Rodriguez E., Romero Lamas M., Romero Vidal A., Ruiz Fernandez R. A., Saborido Silva J. J., Santamarina Rios C., Sellam S., Van Hulse C. B., Vazquez Regueiro P., Jaimes Elles S. J., Jashal B. K., Martinez Vidal F., Mazorra de Cos J., Oyanguren A., Rebollo De Miguel M., Remon Alepuz C., Ruiz Vidal J., Sanderswood I., Alessio F., An L., Batista Lopes J. C., Betti F., Boyer A., Bregliozzi G., Brodski M., Burr C., Buytaert J., Byczynski W., Caillet A., Calegari D., Cattaneo M., Cavallero G., Chadaj B., Charpentier Ph., Ciezarek G., Cifra P., Clemencic M., Closier J., Coco V., Collins P., Colombo T., Corti G., Couturier B., D'Ambrosio C., de Boer J., de Oliveira R., Denis C., Dijkstra H., Dufour L., Dumps R., Durante P., Feo M., Fernandez Declara P., Ferreira R., Ferro-Luzzi M., Forty R., Fournier C., Frank M., Frei C., Galka M., Gambetta S., Gaspar C., Gebolis P. M., Gkougkousis E. L., Granado Cardoso L. A., Grub N., Gys T., Haen C., Haimberger J., Halvorsen M. M., Hasse C., Hatch M., Hemmer F. H., Henry L., Jacobsson R., Jakobsen S., Jamet O., Jost B., Jurik N., Karacson M., Kaufmann K., Keizer F., Krawczyk R. D., Lacarrere D., Lemaitre F., Li P., Lindner R., Martinazzoli L., Matev R., Mathe Z., Mazurek M., Milovanovic M., Morris A. B., Muller D., Nanut T., Neufeld N., Pais P. R., Pearce A., Pepe Altarelli M., Perro A., Piedigrossi D., Pisani F., Polyakov I., Ponce S., Pons X., Redi F., Rochet J., Rolf D. L., Roloff P., Roy L., Ruf T., Salomoni M., Schindler H., Schmidt B., Schneider T., Schopper A., Schwemmer R., Sciuccati A., Sestak J., Seyfert P., Sriskaran V., Stagni F., Stahl M., Stahl S., Stein E. N., Szymanski M., Teubert F., Thomas E., Valassi A., Valat S., Van Stenis M., Vazquez Sierra C., Viana Barbosa J. V., Viel K. J., Voneki B., Wyllie K., Zenaiev O., Bachmayer M., Bay A., Bernard F., Blanc F., Bouchiba S. A., Celani S., Cholak S., De Cian M., Ek-In S., Faria M., Ferreira Lopes L., Frei R., Girard O. G., Graverini E., Haefeli G., Hill D., Hopchev P. H., Kirsebom V. S., Kuonen A. K., Macko V., Nakada T., Niel E. M., Quagliani R., Rodrigues A. B., Schneider O., Schulte S., Shchutska L., Stramaglia M. E., Trippl C., Van Dijk M., Venkateswaran A., Vieites Diaz M., Zaffaroni E., Abellan Beteta C., Andersson M., Atzeni M., Bellee V., Bernet R., Betancourt C., Bezshyiko Ia., Buonaura A., Craik D. C., De Simone D., Denysenko V., Eschle J., Esen S., Ferrillo M., Lancierini D., Manzari C. A., Mathad A., Meier-Villardita L., Muller K., Owen P., Serra N., Smith E., Steinkamp O., Terentev A., Kandybei S., Chernyshenko S., Dobishuk V., Koliiev S., Kot O., Pugatch V., Cooke N., Plews J., Sahoo N., Slater M. W., Swallow P. N., Thompson D. J. D., Watson N. K., Adinolfi M., Amey J. L., Bhasin S., Chapman M. G., Clark K., Lane R., Maddrell-Mander S., Madhan Mohan L. R., Marshall A. M., Naik P., Petridis K., Pomery G. J., Rademacker J. H., Reich J., Trilov S. M., Velthuis J. J., Wang R., Westhenry B. D. C., Alvarez Cartelle P., Bartolini M., Bishop F. C. R., Blago M. P., Cliff H. V., Foulds-Holt D., Garsed P. J., Gibson V., Haines S. C., Jones C. R., Lovell G. H., Sigurdsson S., Smeaton J. G., Williams I., Williams R., Wotton S. A., Abdelmotteleb A. S. W., Abudinen F., Back J. J., Beck A., Blake T., Cicala M. F., Garcia Martin L. M., Gershon T., Henderson R. D. L., Hunter R. J., Jones T. P., Kenzie M., Kreps M., Latham T., Lupton O., Millard E., Monk M., Morris A. G., Muhammad E., Pagare B., Paolucci L., Ramos Pernas M., Vesterinen M., Ward J. A., Wiederhold A. R., Xu M., Barclay P., Booth M. J., Brummitt A. J., Canfer S., Easo S., Lin T., Loveridge P., Nandakumar R., O'Dell J., Papanestis A., Ricciardi S., Richards D. S., Wilson F. F., Barter W., Clarke P. E. L., Cowan G. A., Currie R., Eisenhardt S., Gizdov K., Luo H., Masic B., Mitchell S. E., Muheim F., Needham M., Oliva F., O'Neil R. H., Ozcelik O., Petrucci S., Richardson-Slipper M., Robertson G., Vrahas C., Webster J., Williams M. R. J., Alexander M., Ashby J., Bobulska D., Doherty F., Douglas L., Flores L., Friday D. A., Grant F., Grillo L., Longstaff I., McHugh N. T., Naik S. A., Schiller M., Soler F. J. P., Spradlin P., Whitehead M., Wraight K., Ackernley T., Bowcock T. J. V., Bridges K., Brown J., Carroll J., Casse G., Chadwick A. J., Chavez Barajas C. A., Farry S., Franco Lima V., Halewood-Leagas T., Hammerich J., Harrison T., Hennessy K., Hutchcroft D., Marshall P. J., Mead J. V., Rinnert K., Rodrigues E., Scherl S., Shears T., Smith N. A., Thomson K. A., Vilella Figueras E., Wormald M., Yeomans L. E., Birch M., Bradley M. J., Ely S., Herd J., McCann M., Murta R., Newcombe R., Patel M., Smith M., Tilquin H., van Herwijnen E., Websdale D., Aliouche Z., Barlow R. J., Bertella C., Bitadze A., Borghi S., Burke A. T., Cobbledick J. L., Davies J. E., Davis A., De Aguiar Francisco O., De Capua S., Dutta D., Ejopu E., Elvin A., Evans T., Fitzpatrick C., Freestone J., Fuzipeg C., Gersabeck E., Gersabeck M., Hansen E. B., Hilton M., Horswill J., Lafferty G., Lane J. J., Langstaff M., Lupato A., McGrath T. H., McNab A., Miller G., Murray D., Pan Y., Parkes C., Perry M., Reiss F., Rodriguez Perez P., Skidmore N., Svihra P., Taneja S., White D. J., Yeung H., Zunica G., Brock M., Cervenkov D., Fischer K. M., Gao R., Gilman A. L., Goncalves Abrantes F., Gruberg Cazon B. R., Harnew N., John M., Kariuki J. M., Lowe A. D., Mackay I., Malde S., Mohammed R. A., Murphy C. H., Pajero T., Pili M., Resmi P. K., Rollings A., Scantlebury Smead L. G., Smallwood J. C., Stanislaus S., Suljik F., Tat M. D., Topp-Joergensen S., Wilkinson G., Delaney B., Hennequin A. M., Johnson D., Kitouni O., Nolte N. S., Richardson K., Williams M., Akar S., Boettcher T., Elashri M. E., Epple E., Grieser N. A., Henderson C., Ilten P., Kautz J. W., Meadows B., Nowak G. N., Pappenheimer C., Slattery K., Sokoloff M. D., Vieira D., Wilkinson M. K., Andrews J. E., Braun S., Davis J., Fernez A. D., Franco Sevilla M., Hadjivasiliou C., Hamilton P. M., Jawahery A., Jiang E., Lutz L. F., O'Bannon T., Parker W., Sun Y., Wimberley J., Da Silva C. L., Dean C. T., Durham J. M., Smith K., Van Hecke H., Wong C. P., Andreou D., Artuso M., Beiter A., Bernstein H. C., Blusk S., Brown C., Buda L., Ding S., Frelier J., Germann D., Guerin S., Keller D. M., Kuhlman A., Li Z., Liang X., Mountain R., Pham H., Pratt D., Rajagopalan R., Rudolph M. S., s Sherman M., Shupperd J. D., Silva Coutinho R., Skwarnicki T., Stone S., Wu H., Yuan X., Egede U., Hadavizadeh T., Singla M., Song R., Walton E. J., Gobel C., Dai L., Yu J., Bursche A., Li H., Liu G., Wang X., Li P. -R., Bian L., Cai H., Huang X., Sun L., Milanes D. A., Monroy I. A., Rodriguez Lopez J. A., Grabowski J. P., Mikhasenko M., Neubert S., Padeken K. O., Sarpis M., Dey B., Duk V., Fantini L., Lollini R., Martelli G., Piccini M., De Bruyn K., Mulder M., Onderwater C. J. G., Bolognani C. S., Campora Perez D. H., de Vries J. A., Lucio Martinez M., Nicotra D., Pawley C. J., Vos K., Duda P., Duras M. M., Felkowski L. F., Kubis S., Bernet Andres S., Calvo Gomez M., Golobardes E., Valls Canudas N., Vilasis-Cardona X., Adlarson P., Eklund L., Kupsc A., Aidala C. A., Chahrour I., Fitzgerald D. S., Lee S. H., Nunez C., Roth J. D., Shangase D. M., Boiaryntseva I., Boyaryntsev A., Grynyov B., Bezshyyko O., Golinka-Bezshyyko L., Orlov V., and Steffens E.
Abstract: The LHCb upgrade represents a major change of the experiment. The detectors have been almost completely renewed to allow running at an instantaneous luminosity five times larger than that of the previous running periods. Readout of all detectors into an all-software trigger is central to the new design, facilitating the reconstruction of events at the maximum LHC interaction rate, and their selection in real time. The experiment's tracking system has been completely upgraded with a new pixel vertex detector, a silicon tracker upstream of the dipole magnet and three scintillating fibre tracking stations downstream of the magnet. The whole photon detection system of the RICH detectors has been renewed and the readout electronics of the calorimeter and muon systems have been fully overhauled. The first stage of the all-software trigger is implemented on a GPU farm. The output of the trigger provides a combination of totally reconstructed physics objects, such as tracks and vertices, ready for final analysis, and of entire events which need further offline reprocessing. This scheme required a complete revision of the computing model and rewriting of the experiment's software.
Published: 2024

8. Evaluating the Performance of Island Kitchen Range Hoods

Author: Walker, IS, Rojas, G, Clark, J, and Sherman, M
Subjects: Indoor Air Quality, Kitchen Ventilation, Cooking, Range Hood, Performance Standard, Indoor Air Quality, Kitchen Ventilation, Cooking, Range Hood, Performance Standard
Abstract: A key aspect of achieving acceptable indoor air quality is source control. Cooking has been recognized as a significant source of pollutants for health impacts (e.g., PM2.5 and NO2) as well as moisture and odour. A common method of controlling this pollutant source is by using a range (or cooker) hood that vents to outside. However, field and laboratory experiments have shown highly variable performance for these devices. We use the capture efficiency metric (the fraction of the pollutants that are exhausted to outside at steady state) to characterize the range hood performance. To address this issue and provide useful information for builders, contractors, designers and home occupants, a laboratory rating method for range hood capture efficiency has recently been developed by LBNL and ASTM. The test method uses standardized emitters to create a heated plume and seed it with tracer gas. The tracer gas measurements in the room, the range hood exhaust and in the ambient air are used to estimate capture efficiency. However, this test method only applies to wall-mounted range hoods. Some range hoods are not wall-mounted: island range hoods are designed to operate over a cooktop in the middle of a room rather than against a wall and downdraft hoods draw air from near the cooktop rather than overhead. This paper discusses the development of a new test apparatus for island and downdraft hoods and presents measured capture efficiency data from example hoods. The results of this work will be used in future revisions to the ASTM standard.
Published: 2018

9. Effects of relic low-head dams on stream denitrification potential: seasonality and biogeochemical controls

Author: Hripto, Johanna, Inamdar, S., Sherman, M., Peck, E., Gold, A. J., Bernasconi, S., Addy, K., and Peipoch, M.
Published: 2022
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10. A Case of Babesiosis Induced Sepsis Hemophagocytic Lymphohistiocytosis Overlap Syndrome in Pennsylvania

Author: Sherman, M., primary, Holden, K., additional, Sweeney, R., additional, Dumont, T.L., additional, and Appiah-Kubi, E., additional
Published: 2024
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11. msCNVS: medium throughput single cell copy number variation sequencing with barcoded library construction free of preamplification toward clinical implementation

Author: Lin, Guanchuan, primary, Peng, Bin, additional, Chen, Caiming, additional, Dong, Zhanying, additional, Xu, Mengchang, additional, Gao, Jinyu, additional, Yu, Jie, additional, Jia, Bei, additional, Luo, Chen, additional, Hua, Rui, additional, Xiao, Changtai, additional, Wang, Linlin, additional, Mai, Liyao, additional, Zhang, Yulong, additional, Lu, Yuanfang, additional, He, Yuanqiao, additional, Song, Yali, additional, Marjani, Sadie L, additional, Zhang, Weimin, additional, Zhang, Junxiao, additional, Zhong, Mei, additional, Quan, Song, additional, Weissman, Sherman M., additional, Zhu, Hao, additional, and Pan, Xinghua, additional
Published: 2024
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12. Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture

Author: Yanfang Lu, Miao Liu, Jennifer Yang, Sherman M. Weissman, Xinghua Pan, Samuel G. Katz, and Siyuan Wang
Subjects: Cytology, QH573-671
Abstract: Abstract The hematopoietic stem cell (HSC) niche has been extensively studied in bone marrow, yet a more systematic investigation into the microenvironment regulation of hematopoiesis in fetal liver is necessary. Here we investigate the spatial organization and transcriptional profile of individual cells in both wild type (WT) and Tet2 −/− fetal livers, by multiplexed error robust fluorescence in situ hybridization. We find that specific pairs of fetal liver cell types are preferentially positioned next to each other. Ligand-receptor signaling molecule pairs such as Kitl and Kit are enriched in neighboring cell types. The majority of HSCs are in direct contact with endothelial cells (ECs) in both WT and Tet2 −/− fetal livers. Loss of Tet2 increases the number of HSCs, and upregulates Wnt and Notch signaling genes in the HSC niche. Two subtypes of ECs, arterial ECs and sinusoidal ECs, and other cell types contribute distinct signaling molecules to the HSC niche. Collectively, this study provides a comprehensive picture and bioinformatic foundation for HSC spatial regulation in fetal liver.
Published: 2021
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13. Sample-multiplexing approaches for single-cell sequencing

Author: Zhang, Yulong, Xu, Siwen, Wen, Zebin, Gao, Jinyu, Li, Shuang, Weissman, Sherman M., and Pan, Xinghua
Published: 2022
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14. Effects of Oral vs Transdermal Estrogen Therapy on Sexual Function in Early Postmenopause: Ancillary Study of the Kronos Early Estrogen Prevention Study (KEEPS).

Author: Taylor, Hugh S, Tal, Aya, Pal, Lubna, Li, Fangyong, Black, Dennis M, Brinton, Eliot A, Budoff, Matthew J, Cedars, Marcelle I, Du, Wei, Hodis, Howard N, Lobo, Rogerio A, Manson, JoAnn E, Merriam, George R, Miller, Virginia M, Naftolin, Frederick, Neal-Perry, Genevieve, Santoro, Nanette F, and Harman, Sherman M
Subjects: Humans, Glucuronates, Estradiol, Progesterone, Estrogens, Conjugated (USP), Estrogens, Progestins, Estrogen Replacement Therapy, Administration, Oral, Administration, Cutaneous, Risk Factors, Follow-Up Studies, Prospective Studies, Double-Blind Method, Psychiatric Status Rating Scales, Postmenopause, Time Factors, Quality of Life, Adult, Middle Aged, Women's Health, Female, Sexual Dysfunction, Physiological, Conjugated, Administration, Oral, Cutaneous, Sexual Dysfunction, Physiological, Opthalmology and Optometry, Public Health and Health Services, Clinical Sciences
Abstract: ImportanceSexual dysfunction, an important determinant of women's health and quality of life, is commonly associated with declining estrogen levels around the menopausal transition.ObjectiveTo determine the effects of oral or transdermal estrogen therapy vs placebo on sexual function in postmenopausal women.Design, setting, and participantsAncillary study of the Kronos Early Estrogen Prevention Study (KEEPS), a 4-year prospective, randomized, double-blinded, placebo-controlled trial of menopausal hormone therapy in healthy, recently menopausal women. Of 727 KEEPS enrollees, 670 agreed to participate in this multicenter ancillary study. Women were 42 to 58 years old, within 36 months from last menstrual period. Data were collected from July 2005 through June 2008 and analyzed from July 2010 through June 2017.InterventionsWomen were randomized to either 0.45 mg/d oral conjugated equine estrogens (o-CEE), 50 µg/d transdermal 17β-estradiol (t-E2), or placebo. Participants also received 200 mg oral micronized progesterone (if randomized to o-CEE or t-E2) or placebo (if randomized to placebo estrogens) for 12 days each month.Main outcomes and measuresAspects of sexual function and experience (desire, arousal, lubrication, orgasm, satisfaction, and pain) were assessed using the Female Sexual Function Inventory (FSFI; range, 0-36 points; higher scores indicate better sexual function). Low sexual function (LSF) was defined as an FSFI overall score of less than 26.55. Distress related to low FSFI score (required for the diagnosis of sexual dysfunction) was not evaluated.ResultsThe 670 participants had a mean (SD) age of 52.7 (2.6) years. The t-E2 treatment was associated with a significant yet moderate improvement in the FSFI overall score across all time points compared with placebo (average efficacy, 2.6; 95% CI, 1.11-4.10; adjusted P = .002). With o-CEE treatment, there was no significant difference in FSFI overall score compared with placebo (mean efficacy, 1.4; 95% CI, -0.1 to 2.8; adjusted P = .13). There was no difference in FSFI overall score between the t-E2 and o-CEE groups on average across 48 months (adjusted P = .22). In the individual domains of sexual function, t-E2 treatment was associated with a significant increase in mean lubrication (0.61; 95% CI, 0.25-0.97; P = .001) and decreased pain (0.67; 95% CI, 0.25-1.09; P = .002) compared with placebo. Overall, the proportion of women with LSF was significantly lower after t-E2 treatment compared with placebo (67%; 95% CI, 55%-77% vs 76%; 95% CI, 67%-83%; P = .04). For o-CEE there was no significant reduction in the odds of LSF.Conclusions and relevanceTreatment with t-E2 modestly improved sexual function in early postmenopausal women, but whether it relieved symptoms of distress is not known.Trial registrationclinicaltrials.gov Identifier: NCT00154180.
Published: 2017

15. Large-scale implementation of pooled RNA extraction and RT-PCR for SARS-CoV-2 detection

Author: Klochendler, A., Eden, A., Klar, A., Geldman, A., Arbel, A., Peretz, A., Shalom, B., Ochana, B.L., Avrahami-Tzfati, D., Neiman, D., Steinberg, D., Ben Zvi, D., Shpigel, E., Atlan, G., Klein, H., Chekroun, H., Shani, H., Hazan, I., Ansari, I., Magenheim, I., Moss, J., Magenheim, J., Peretz, L., Feigin, L., Saraby, M., Sherman, M., Bentata, M., Avital, M., Kott, M., Peyser, M., Weitz, M., Shacham, M., Grunewald, M., Sasson, N., Wallis, N., Azazmeh, N., Tzarum, N., Fridlich, O., Sher, R., Condiotti, R., Refaeli, R., Ben Ami, R., Zaken-Gallili, R., Helman, R., Ofek, S., Tzaban, S., Piyanzin, S., Anzi, S., Dagan, S., Lilenthal, S., Sido, T., Licht, T., Friehmann, T., Kaufman, Y., Pery, A., Saada, A., Dekel, A., Yeffet, A., Shaag, A., Michael-Gayego, A., Shay, E., Arbib, E., Onallah, H., Ben-Meir, K., Levinzon, L., Cohen-Daniel, L., Natan, L., Hamdan, M., Rivkin, M., Shwieki, M., Vorontsov, O., Barsuk, R., Abramovitch, R., Gutorov, R., Sirhan, S., Abdeen, S., Yachnin, Y., Daitch, Y., Ben-Ami, R., Seidel, M., Gurel-Gurevich, O., Yassour, M., Meshorer, E., Benedek, G., Fogel, I., Oiknine-Djian, E., Gertler, A., Rotstein, Z., Lavi, B., Dor, Y., Wolf, D.G., Salton, M., and Drier, Y.
Published: 2020
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16. Higher systolic and diastolic blood pressures in recently postmenopausal women are associated with greater WMH more than a decade later in the KEEPS Continuation

Author: Kara, Firat, primary, Tosakulwong, Nirubol, additional, Lesnick, Timothy G., additional, Fought, Angela J., additional, Schwarz, Christopher G., additional, Senjem, Matthew L., additional, Fields, Julie A., additional, Min, Paul H, additional, Lowe, Val J., additional, Jack, Clifford R., additional, Bailey, Kent R., additional, James, Taryn T., additional, Lobo, Rogerio A., additional, Manson, JoAnn E., additional, Pal, Lubna, additional, Hammers, Dustin B., additional, Malek‐Ahmadi, Michael H., additional, Cedars, Marcelle I., additional, Naftolin, Frederick N., additional, Miller, Virginia M., additional, Harman, Sherman M., additional, Dowling, Maritza N., additional, Gleason, Carey E., additional, and Kantarci, Kejal, additional
Published: 2023
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17. Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture

Author: Lu, Yanfang, Liu, Miao, Yang, Jennifer, Weissman, Sherman M., Pan, Xinghua, Katz, Samuel G., and Wang, Siyuan
Published: 2021
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18. Sex and psychiatric comorbidity correlates of the premonitory urge for tic scale in youth with persistent tic disorders

Author: Edwards, K. R., Raines, J. M., Winnick, J. B., Sherman, M. F., Higginson, C. I., Navin, K., Conteh, F., Ricketts, E. J., and Specht, M. W.
Published: 2020
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19. Simplified Methods for Combining Natural and Mechanical Ventilation:

Author: Hurel, N, Sherman, M, and Walker, I
Subjects: Unbalanced ventilation, infiltration, REGCAP simulation, empirical models, superposition
Abstract: In determining ventilation rates, it is often necessary to combine naturally-driven ventilation, such as infiltration, with mechanical systems. Modern calculation methods are sufficiently powerful that this can be done from first principles with time varying flows, but for some purposes simplified methods of combining the mechanical and natural ventilation are required—we call this “superposition”. An example of superposition would be ventilation standards that may pre-calculate some quantities within the body of the standard. When there are balanced mechanical systems, the solution is simple additivity, because a balanced system does not impact the internal pressure of the space. Unbalanced systems, however, change internal pressures and therefore can impact natural ventilation in such a way as to make it sub-additive. Several sub-additive superposition models are found in the literature. This paper presents the results of millions of hours of simulations of the physically correct solution, which span a broad range of climates, air leakage and structural conditions. This wide range of data allows for the comparison of three superposition models from the literature and eight new ones. The results show that by using the appropriate model(s) superposition errors can be reduced significantly, from the 20% over-prediction of simple linear addition to 1% or less.
Published: 2015

20. Spontaneous emergence of overgrown molar teeth in a colony of Prairie voles (Microtus ochrogaster)

Author: Jheon, Andrew, Shah, Nirao, Klein, Ophir, Manoli, Devanand, Jheon, AH, Prochazkova, M, Sherman, M, Manoli, DS, Shah, NM, and Carbone, L
Abstract: © 2015 WCSS.Continuously growing incisors are common to all rodents, which include the Microtus genus of voles. However, unlike many rodents, voles also possess continuously growing molars. Here, we report spontaneous molar defects in a population of Prair
Published: 2015

21. Capsule Endoscopy

Author: Yu, Siegfried, Sridhar, Subbaramiah, Chamberlain, Sherman M., Wu, George Y., Series editor, and Sridhar, Subbaramiah, editor
Published: 2018
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22. Integrating Single-Cell Transcriptome and Network Analysis to Characterize the Therapeutic Response of Chronic Myeloid Leukemia

Author: Jialu Ma, Nathan Pettit, John Talburt, Shanzhi Wang, Sherman M. Weissman, and Mary Qu Yang
Subjects: single cell, RNA sequencing, chronic myeloid leukemia, network analysis, TKI responses, BCR-ABL, Biology (General), QH301-705.5, Chemistry, QD1-999
Abstract: Chronic myeloid leukemia (CML) is a myeloproliferative disease characterized by a unique BCR-ABL fusion gene. Tyrosine kinase inhibitors (TKIs) were developed to target the BCR-ABL oncoprotein, inhibiting its abnormal kinase activity. TKI treatments have significantly improved CML patient outcomes. However, the patients can develop drug resistance and relapse after therapy discontinues largely due to intratumor heterogeneity. It is critical to understand the differences in therapeutic responses among subpopulations of cells. Single-cell RNA sequencing measures the transcriptome of individual cells, allowing us to differentiate and analyze individual cell populations. Here, we integrated a single-cell RNA sequencing profile of CML stem cells and network analysis to decipher the mechanisms of distinct TKI responses. Compared to normal hematopoietic stem cells, a set of genes that were concordantly differentially expressed in various types of stem cells of CML patients was revealed. Further transcription regulatory network analysis found that most of these genes were directly controlled by one or more transcript factors and the genes have more regulators in the cells of the patients who responded to the treatment. The molecular markers including a known drug-resistance gene and novel gene signatures for treatment response were also identified. Moreover, we combined protein–protein interaction network construction with a cancer drug database and uncovered the drugs that target the marker genes directly or indirectly via the protein interactions. The gene signatures and their interacted proteins identified by this work can be used for treatment response prediction and lead to new strategies for drug resistance monitoring and prevention. Our single-cell-based findings offered novel insights into the mechanisms underlying the therapeutic response of CML.
Published: 2022
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23. Comparative Effectiveness of a Second Tumor Necrosis Factor Inhibitor Versus a Non–Tumor Necrosis Factor Biologic in the Treatment of Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis

Author: Mannion, Melissa L., Amin, Shahla, Balevic, Stephen, Chang, Min‐Lee, Correll, Colleen K., Kearsley‐Fleet, Lianne, Hyrich, Kimme L., Beukelman, Timothy, Aamir, R., Abulaban, K., Adams, A., Aguiar Lapsia, C., Akinsete, A., Akoghlanian, S., Al Manaa, M., AlBijadi, A., Allenspach, E., Almutairi, A., Alperin, R., Amarilyo, G., Ambler, W., Amoruso, M., Angeles‐Han, S., Ardoin, S., Armendariz, S., Asfaw, L., Aviran Dagan, N., Bacha, C., Balboni, I., Balevic, S., Ballinger, S., Baluta, S., Barillas‐Arias, L., Basiaga, M., Baszis, K., Baxter, S., Becker, M., Begezda, A., Behrens, E., Beil, E., Benseler, S., Bermudez‐Santiago, L., Bernal, W., Bigley, T., Bingham, C., Binstadt, B., Black, C., Blackmon, B., Blakley, M., Bohnsack, J., Boneparth, A., Bradfield, H., Bridges, J., Brooks, E., Brothers, M., Brunner, H., Buckley, L., Buckley, M., Buckley, M., Bukulmez, H., Bullock, D., Canna, S., Cannon, L., Canny, S., Cartwright, V., Cassidy, E., Castro, D., Chalom, E., Chang, J., Chang, M., Chang, J., Chang‐Hoftman, A., Chen, A., Chiraseveenuprapund, P., Ciaglia, K., Co, D., Cohen, E., Collinge, J., Conlon, H., Connor, R., Cook, K., Cooper, A., Cooper, J., Corbin, K., Correll, C., Cron, R., Curry, M., Dalrymple, A., Datyner, E., Davis, T., De Ranieri, D., Dean, J., DeCoste, C., Dedeoglu, F., DeGuzman, M., Delnay, N., DeSantis, E., Devine, R., Dhalla, M., Dhanrajani, A., Dissanayake, D., Dizon, B., Drapeau, N., Drew, J., Driest, K., Du, Q., Duncan, E., Dunnock, K., Durkee, D., Dvergsten, J., Eberhard, A., Ede, K., Edelheit, B., Edens, C., El Tal, T., Elder, M., Elzaki, Y., Fadrhonc, S., Failing, C., Fair, D., Favier, L., Feldman, B., Fennell, J., Ferguson, P., Ferguson, I., Figueroa, C., Flanagan, E., Fogel, L., Fox, E., Fox, M., Franklin, L., Fuhlbrigge, R., Fuller, J., Furey, M., Futch‐West, T., Gagne, S., Gennaro, V., Gerstbacher, D., Gilbert, M., Gironella, A., Glaser, D., Goh, I., Goldsmith, D., Gorry, S., Goswami, N., Gottlieb, B., Graham, T., Grevich, S., Griffin, T., Grim, A., Grom, A., Guevara, M., Hahn, T., Halyabar, O., Hamda Natur, M., Hammelev, E., Hammond, T., Harel, L., Harris, J., Harry, O., Hausmann, J., Hay, A., Hays, K., Hayward, K., Henderson, L., Henrickson, M., Hersh, A., Hickey, K., Hiraki, L., Hiskey, M., Hobday, P., Hoffart, C., Holland, M., Hollander, M., Hong, S., Horton, D., Horwitz, M., Hsu, J., Huber, A., Huberts, A., Huggins, J., Huie, L., Hui‐Yuen, J., Ibarra, M., Imlay, A., Imundo, L., Inman, C., Jackson, A., James, K., Janow, G., Jared, S., Jiang, Y., Johnson, L., Johnson, N., Jones, J., Kafisheh, D., Kahn, P., Kaidar, K., Kasinathan, S., Kaur, R., Kessler, E., Kienzle, B., Kim, S., Kimura, Y., Kingsbury, D., Kitcharoensakkul, M., Klausmeier, T., Klein, K., Klein‐Gitelman, M., Knight, A., Kovalick, L., Kramer, S., Kremer, C., Kudas, O., LaFlam, T., Lang, B., Lapidus, S., Lapin, B., Lasky, A., Lawler, C., Lawson, E., Laxer, R., Lee, P., Lee, P., Lee, T., Lee, A., Leisinger, E., Lentini, L., Lerman, M., Levinsky, Y., Levy, D., Li, S., Lieberman, S., Lim, L., Limenis, E., Lin, C., Ling, N., Lionetti, G., Livny, R., Lloyd, M., Lo, M., Long, A., Lopez‐Peña, M., Lovell, D., Luca, N., Lvovich, S., Lytch, A., Ma, M., Machado, A., MacMahon, J., Madison, J., Mannion, M., Manos, C., Mansfield, L., Marston, B., Mason, T., Matchett, D., McAllister, L., McBrearty, K., McColl, J., McCurdy, D., McDaniels, K., McDonald, J., Meidan, E., Mellins, E., Mian, Z., Miettunen, P., Miller, M., Milojevic, D., Mitacek, R., Modica, R., Mohan, S., Moore, T., Moore, K., Moorthy, L., Moreno, J., Morgan, E., Moyer, A., Murante, B., Murphy, A., Muscal, E., Mwizerwa, O., Najafi, A., Nanda, K., Nasah, N., Nassi, L., Nativ, S., Natter, M., Nearanz, K., Neely, J., Newhall, L., Nguyen, A., Nigrovic, P., Nocton, J., Nolan, B., Nowicki, K., Oakes, R., Oberle, E., Ogbonnaya‐Whittesley, S., Ogbu, E., Oliver, M., Olveda, R., Onel, K., Orandi, A., Padam, J., Paller, A., Pan, N., Pandya, J., Panupattanapong, S., Toledano, A. Pappo, Parsons, A., Patel, J., Patel, P., Patrick, A., Patrizi, S., Paul, S., Perfetto, J., Perron, M., Peskin, M., Ponder, L., Pooni, R., Prahalad, S., Puplava, B., Quinlan‐Waters, M., Rabinovich, C., Rafko, J., Rahimi, H., Rampone, K., Ramsey, S., Randell, R., Ray, L., Reed, A., Reed, A., Reid, H., Reiff, D., Richins, S., Riebschleger, M., Rife, E., Riordan, M., Riskalla, M., Robinson, A., Robinson, L., Rodgers, L., Rodriquez, M., Rogers, D., Ronis, T., Rosado, A., Rosenkranz, M., Rosenwasser, N., Rothermel, H., Rothman, D., Rothschild, E., Roth‐Wojcicki, E., Rouster‐Stevens, K., Rubinstein, T., Rupp, J., Ruth, N., Sabbagh, S., Sadun, R., Santiago, L., Saper, V., Sarkissian, A., Scalzi, L., Schahn, J., Schikler, K., Schlefman, A., Schmeling, H., Schmitt, E., Schneider, R., Schulert, G., Schultz, K., Schutt, C., Seper, C., Sheets, R., Shehab, A., Shenoi, S., Sherman, M., Shirley, J., Shishov, M., Siegel, D., Singer, N., Sivaraman, V., Sloan, E., Smith, C., Smith, J., Smitherman, E., Soep, J., Son, Mary B., Sosna, D., Spencer, C., Spiegel, L., Spitznagle, J., Srinivasalu, H., Stapp, H., Steigerwald, K., Stephens, A., Sterba Rakovchik, Y., Stern, S., Stevens, B., Stevenson, R., Stewart, K., Stewart, W., Stingl, C., Stoll, M., Stringer, E., Sule, S., Sullivan, J., Sundel, R., Sutter, M., Swaffar, C., Swayne, N., Syed, R., Symington, T., Syverson, G., Szymanski, A., Taber, S., Tal, R., Tambralli, A., Taneja, A., Tanner, T., Tarvin, S., Tate, L., Taxter, A., Taylor, J., Tesher, M., Thakurdeen, T., Theisen, A., Thomas, B., Thomas, L., Thomas, N., Ting, T., Todd, C., Toib, D., Toib, D., Torok, K., Tory, H., Toth, M., Tse, S., Tsin, C., Twachtman‐Bassett, J., Twilt, M., Valcarcel, T., Valdovinos, R., Vallee, A., Van Mater, H., Vandenbergen, S., Vannoy, L., Varghese, C., Vasquez, N., Vega‐Fernandez, P., Velez, J., Verbsky, J., Verstegen, R., Scheven, E., Vora, S., Wagner‐Weiner, L., Wahezi, D., Waite, H., Walker, B., Walters, H., Waterfield, M., Waters, A., Weiser, P., Weiss, P., Weiss, J., Wershba, E., Westheuser, V., White, A., Widrick, K., Williams, C., Wong, S., Woolnough, L., Wright, T., Wu, E., Yalcindag, A., Yasin, S., Yeung, R., Yomogida, K., Zeft, A., Zhang, Y., Zhao, Y., and Zhu, A.
Abstract: The objective of this study was to compare the effectiveness of a second tumor necrosis factor inhibitor (TNFi) versus a non‐TNFi biologic following discontinuation of a TNFi for patients with polyarticular‐course juvenile idiopathic arthritis (pJIA). Using the Childhood Arthritis and Rheumatology Research Alliance Registry, patients with pJIA who started receiving a second biologic following a first TNFi were identified. Patients were required to have no active uveitis on the index date and a visit six months after the index date. Outcome measures included Clinical Juvenile Arthritis Disease Activity Score with a maximum of 10 active joints (cJADAS10), cJADAS10 inactive disease (ID; ≤2.5) and cJADAS10 minimal disease activity (MiDA; ≤5). Multiple imputation was used to account for missing data. Adjusted odds ratios (aORs) were calculated using propensity score quintiles to compare outcomes at six months following second biologic initiation. There were 216 patients included, 84% initially received etanercept, and most patients stopped receiving it because of its ineffectiveness (74%). A total of 183 (85%) started receiving a second TNFi, and 33 (15%) started receiving a non‐TNFi. Adalimumab was the most common second biologic received (71% overall, 84% of second TNFi), and tocilizumab was the most common non‐TNFi second biologic received (9% overall, 58% of non‐TNFi). There was no difference between receiving TNFi versus non‐TNFi in cJADAS10 ID (29% vs 25%; aOR 1.23, 95% confidence interval [CI] 0.47–3.20) or at least MiDA (43% vs 39%; aOR 1.11, 95% CI 0.47–2.62) at six months. Most patients with pJIA started receiving TNFi rather than non‐TNFi as their second biologic, and there were no differences in disease activity at six months.
Published: 2024
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24. Shallow Encoding and Forgetting Are Associated with Dependence in Instrumental Activities of Daily Living Among Older Adults Living with HIV Infection

Author: Fazeli, PL, Doyle, KL, Scott, JC, Iudicello, JE, Casaletto, KB, Weber, E, Moore, DJ, Morgan, EE, Grant, I, Woods, SP, Hampton Atkinson, J, Ellis, RJ, Allen McCutchan, J, Marcotte, TD, Marquie-Beck, J, Sherman, M, Letendre, S, Capparelli, E, Schrier, R, Rosario, D, LeBlanc, S, Heaton, RK, Cherner, M, Dawson, M, Jernigan, T, Fennema-Notestine, C, Archibald, SL, Hesselink, J, Annese, J, Taylor, MJ, Masliah, E, Achim, C, Everall, I, Richman, D, Smith, DM, Lipton, S, Gamst, AC, Cushman, C, Abramson, I, Vaida, F, Deutsch, R, and Umlauf, A
Subjects: Psychology, Clinical and Health Psychology, Applied and Developmental Psychology, Rehabilitation, HIV/AIDS, Neurodegenerative, Behavioral and Social Science, Acquired Cognitive Impairment, Brain Disorders, Clinical Research, Infectious Diseases, Sexually Transmitted Infections, Neurosciences, Aging, Infection, Activities of Daily Living, Adult, Aged, Cohort Studies, Disabled Persons, Female, HIV Infections, Humans, Male, Memory Disorders, Middle Aged, Neuropsychological Tests, Surveys and Questionnaires, Verbal Learning, Disability, Everyday functioning, Learning and memory, HIV Neurobehavioral Research Program (HNRP) Group, Cognitive Sciences, Clinical Psychology, Applied and developmental psychology, Biological psychology, Clinical and health psychology
Abstract: Aging and HIV are both risk factors for memory deficits and declines in real-world functioning. However, we know little about the profile of memory deficits driving instrumental activities of daily living (IADL) declines across the lifespan in HIV. This study examined 145 younger (
Published: 2014

25. Cardiometabolic outcomes in Kronos Early Estrogen Prevention Study continuation: 14-year follow-up of a hormone therapy trial

Author: Kantarci, Kejal, primary, Tosakulwong, Nirubol, additional, Lesnick, Timothy G., additional, Kara, Firat, additional, Kendall-Thomas, June, additional, Kapoor, Ekta, additional, Fields, Julie A., additional, James, Taryn T., additional, Lobo, Rogerio A., additional, Manson, JoAnn E., additional, Pal, Lubna, additional, Hammers, Dustin B., additional, Malek-Ahmadi, Michael, additional, Cedars, Marcelle I., additional, Naftolin, Frederick N., additional, Santoro, Nanette, additional, Miller, Virginia M., additional, Harman, Sherman M., additional, Dowling, N. Maritza, additional, and Gleason, Carey E., additional
Published: 2023
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26. Shortcut barcoding and early pooling for scalable multiplex single-cell reduced-representation CpG methylation sequencing at single nucleotide resolution

Author: Mai, Liyao, primary, Wen, Zebin, additional, Zhang, Yulong, additional, Gao, Yu, additional, Lin, Guanchuan, additional, Lian, Zhiwei, additional, Yang, Xiang, additional, Zhou, Jingjing, additional, Lin, Xianwei, additional, Luo, Chaochao, additional, Peng, Wanwan, additional, Chen, Caiming, additional, Peng, Jiajia, additional, Liu, Duolian, additional, Marjani, Sadie L, additional, Tao, Qian, additional, Cui, Yongping, additional, Zhang, Junxiao, additional, Wu, Xuedong, additional, Weissman, Sherman M, additional, and Pan, Xinghua, additional
Published: 2023
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27. 237 Effect of an ED-ICU on Emergency Department Billing and Coding

Author: Sherman, M., primary, Kan, V., additional, and Reznek, M., additional
Published: 2023
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28. SEX DIFFERENCES IN THE PRESENTATION, TREATMENT AND OUTCOMES OF PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEREMIA

Author: Al-Baldawi, Z., primary, Brown, L., additional, Ruel, I., additional, Baass, A., additional, Bergeron, J., additional, Cermakova, L., additional, Couture, P., additional, Gaudet, D., additional, Francis, G., additional, Hegele, R., additional, Iatan, I., additional, Mancini, G., additional, McCrindle, B., additional, Sherman, M., additional, Genest, J., additional, and Brunham, L., additional
Published: 2023
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29. 41 Analysis of an Emergency Department Extubation Protocol Using Readiness-To-Wean and Rapid Shallow Breathing Index

Author: Sherman, M., primary, Yuan, R., additional, Kan, V., additional, and Reznek, M., additional
Published: 2023
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30. Telomere Maintenance-Associated PML Is a Potential Specific Therapeutic Target of Human Colorectal Cancer

Author: Peng Gong, Hua Wang, Jingsong Zhang, Yudong Fu, Zhengmao Zhu, Jinmiao Wang, Yu Yin, Haiying Wang, Zhongcheng Zhou, Jiao Yang, Linlin Liu, Mo Gou, Ming Zeng, Jinghua Yuan, Feng Wang, Xinghua Pan, Rong Xiang, Sherman M. Weissman, Feng Qi, and Lin Liu
Subjects: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Telomere length maintenance is essential for cell proliferation, which is particularly prominent in cancer. We validate that the primary colorectal tumors exhibit heterogeneous telomere lengths but mostly (90%) short telomeres relative to normal tissues. Intriguingly, relatively short telomeres are associated with tumor malignancy as indicated by poorly differentiated state, and these tumors contain more cancer stem-like cells (CSLCs) identified by several commonly used markers CD44, EPHB2 or LGR5. Moreover, promyelocytic leukemia (PML) and ALT-associated PML nuclear bodies (APBs) are frequently found in tumors with short telomeres and high proliferation. In contrast, distant normal tissues rarely or only minimally express PML. Inhibition of PML and APBs by an ATR inhibitor decreases proliferation of CSLCs and organoids, suggesting a potential therapeutic target to progressive colorectal tumors. Together, telomere maintenance underling tumor progression is connected with CSLCs.
Published: 2019
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31. Local and global chromatin interactions are altered by large genomic deletions associated with human brain development

Author: Xianglong Zhang, Ying Zhang, Xiaowei Zhu, Carolin Purmann, Michael S. Haney, Thomas Ward, Arineh Khechaduri, Jie Yao, Sherman M. Weissman, and Alexander E. Urban
Subjects: Science
Abstract: Copy number variants in the human genome (CNVs) are associated with neurodevelopmental and psychiatric disorders such as schizophrenia and autism. Here the authors investigate how the large deletion CNV on chromosome 22q11.2 alters chromatin organization.
Published: 2018
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32. Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single‐Cell Analysis of Transcriptome and Telomeres

Author: Hua Wang, Peng Gong, Tong Chen, Shan Gao, Zhenfeng Wu, Xiaodong Wang, Jie Li, Sadie L. Marjani, José Costa, Sherman M. Weissman, Feng Qi, Xinghua Pan, and Lin Liu
Subjects: cancer stem cells, colorectal cancer, epithelial cells, heterogeneity, single‐cell RNA‐seq, telomere length, Science
Abstract: Abstract Cancer stem cells (CSCs) presumably contribute to tumor progression and drug resistance, yet their definitive features have remained elusive. Here, simultaneous measurement of telomere length and transcriptome in the same cells enables systematic assessment of CSCs in primary colorectal cancer (CRC). The in‐depth transcriptome profiled by SMART‐seq2 is independently validated by high‐throughput scRNA‐seq using 10 × Genomics. It is found that rare CSCs exist in dormant state and display plasticity toward cancer epithelial cells (EPCs) that essentially are presumptive tumor‐initiating cells (TICs), while both retaining the prominent signaling pathways including WNT, TGF‐β, and HIPPO/YAP. Moreover, CSCs exhibit chromosome copy number variation (CNV) pattern resembling cancer EPCs but distinct from normal stem cells, suggesting the phylogenetic relationship between CSCs and cancer EPCs. Notably, CSCs maintain shorter telomeres and possess minimal telomerase activity consistent with their nonproliferative nature, unlike cancer EPCs. Additionally, the specific signature of CSCs particularly NOTUM, SMOC2, BAMBI, PHLDA1, and TNFRSF19 correlates with the prognosis of CRC. These findings characterize the heterogeneity of CSCs and their linkage to cancer EPCs/TICs, some of which are conventionally regarded as CSCs.
Published: 2021
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33. Lipid Profiles, Inflammatory Markers, and Insulin Therapy in Youth with Type 2 Diabetes

Author: McKay, S., Haymond, M., Anderson, B., Bush, C., Gunn, S., Holden, H., Jones, S.M., Jeha, G., McGirk, S., Thamotharan, S., Cuttler, L., Abrams, E., Casey, T., Dahms, W., Ievers-Landis, C., Kaminski, B., Koontz, M., MacLeish, S., McGuigan, P., Narasimhan, S., Geffner, M., Barraza, V., Chang, N., Conrad, B., Dreimane, D., Estrada, S., Fisher, L., Fleury-Milfort, E., Hernandez, S., Hollen, B., Kaufman, F., Law, E., Mansilla, V., Miller, D., Muñoz, C., Ortiz, R., Ward, A., Wexler, K., Xu, Y.K., Yasuda, P., Berkowitz, R., Boyd, S., Johnson, B., Kaplan, J., Keating, C., Lassiter, C., Lipman, T., McGinley, G., McKnight, H., Schwartzman, B., Willi, S., Arslanian, S., Foster, S., Galvin, B., Hannon, T., Kriska, A., Marcus, M., Songer, T., Venditti, E., Goland, R., Gallagher, D., Kringas, P., Leibel, N., Ng, D., Ovalles, M., Seidman, D., Laffel, L., Goebel-Fabbri, A., Hall, M., Higgins, L., Keady, J., Malloy, M., Milaszewski, K., Rasbach, L., Nathan, D.M., Angelescu, A., Bissett, L., Ciccarelli, C., Delahanty, L., Goldman, V., Hardy, O., Larkin, M., Levitsky, L., McEachern, R., Norman, D., Nwosu, D., Park-Bennett, S., Richards, D., Sherry, N., Steiner, B., Tollefsen, S., Carnes, S., Dempsher, D., Flomo, D., Whelan, T., Wolff, B., Bowerman, D., Bristol, S., Bulger, J., Hartsig, J., Izquierdo, R., Kearns, J., Saletsky, R., Trief, P., Zeitler, P., Abramson, N., Bradhurst, A., Celona-Jacobs, N., Higgins, J., Kelsey, M., Klingensmith, G., Witten, T., Copeland, K., Boss, E., Brown, R., Chadwick, J., Chalmers, L., Chernausek, S., Hebensperger, A., Macha, C., Newgent, R., Nordyke, A., Olson, D., Poulsen, T., Pratt, L., Preske, J., Schanuel, J., Sternlof, S., Lynch, J., Amodei, N., Barajas, R., Cody, C., Hale, D., Hernandez, J., Ibarra, C., Morales, E., Rivera, S., Rupert, G., Wauters, A., White, N., Arbeláez, A., Jones, J., Jones, T., Sadler, M., Tanner, M., Timpson, A., Welch, R., Caprio, S., Grey, M., Guandalini, C., Lavietes, S., Rose, P., Syme, A., Tamborlane, W., Hirst, K., Edelstein, S., Feit, P., Grover, N., Long, C., Pyle, L., Linder, B., Harting, J., Shepherd, J., Fan, B., Marquez, L., Sherman, M., Wang, J., Nichols, M., Mayer-Davis, E., Liu, Y., Lima, J., Puccella, J., Ricketts, E., Danis, R., Domalpally, A., Goulding, A., Neill, S., Vargo, P., Wilfley, D., Aldrich-Rasche, D., Franklin, K., Massmann, C., O'Brien, D., Patterson, J., Tibbs, T., Van Buren, D., Palmert, M., Ratner, R., Dremaine, D., Silverstein, J., Levitt Katz, Lorraine E., Bacha, Fida, Gidding, Samuel S., Weinstock, Ruth S., El ghormli, Laure, Libman, Ingrid, Nadeau, Kristen J., Porter, Kristin, and Marcovina, Santica
Published: 2018
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34. Cardiac Biomarkers in Youth with Type 2 Diabetes Mellitus: Results from the TODAY Study

Author: McKay, S., Haymond, M., Anderson, B., Bush, C., Gunn, S., Holden, H., Jones, S.M., Jeha, G., McGirk, S., Thamotharan, S., Cuttler, L., Abrams, E., Casey, T., Dahms, W., Ievers-Landis, C., Kaminski, B., Koontz, M., MacLeish, S., McGuigan, P., Narasimhan, S., Geffner, M., Barraza, V., Chang, N., Conrad, B., Dreimane, D., Estrada, S., Fisher, L., Fleury-Milfort, E., Hernandez, S., Hollen, B., Kaufman, F., Law, E., Mansilla, V., Miller, D., Muñoz, C., Ortiz, R., Ward, A., Wexler, K., Xu, Y.K., Yasuda, P., Levitt Katz, L., Berkowitz, R., Boyd, S., Johnson, B., Kaplan, J., Keating, C., Lassiter, C., Lipman, T., McGinley, G., McKnight, H., Schwartzman, B., Willi, S., Arslanian, S., Bacha, F., Foster, S., Galvin, B., Hannon, T., Kriska, A., Libman, I., Marcus, M., Porter, K., Songer, T., Venditti, E., Goland, R., Gallagher, D., Kringas, P., Leibel, N., Ng, D., Ovalles, M., Seidman, D., Laffel, L., Goebel-Fabbri, A., Hall, M., Higgins, L., Keady, J., Malloy, M., Milaszewski, K., Rasbach, L., Nathan, D.M., Angelescu, A., Bissett, L., Ciccarelli, C., Delahanty, L., Goldman, V., Hardy, O., Larkin, M., Levitsky, L., McEachern, R., Norman, D., Nwosu, D., Park-Bennett, S., Richards, D., Sherry, N., Steiner, B., Tollefsen, S., Carnes, S., Dempsher, D., Flomo, D., Whelan, T., Wolff, B., Weinstock, R., Bowerman, D., Bristol, S., Bulger, J., Hartsig, J., Izquierdo, R., Kearns, J., Saletsky, R., Trief, P., Zeitler, P., Abramson, N., Bradhurst, A., Celona-Jacobs, N., Higgins, J., Kelsey, M., Klingensmith, G., Nadeau, K., Witten, T., Copeland, K., Boss, E., Brown, R., Chadwick, J., Chalmers, L., Chernausek, S., Hebensperger, A., Macha, C., Newgent, R., Nordyke, A., Olson, D., Poulsen, T., Pratt, L., Preske, J., Schanuel, J., Sternlof, S., Lynch, J., Amodei, N., Barajas, R., Cody, C., Hale, D., Hernandez, J., Ibarra, C., Morales, E., Rivera, S., Rupert, G., Wauters, A., White, N., Arbeláez, A., Jones, J., Jones, T., Sadler, M., Tanner, M., Timpson, A., Welch, R., Caprio, S., Grey, M., Guandalini, C., Lavietes, S., Rose, P., Syme, A., Tamborlane, W., Hirst, K., Edelstein, S., Feit, P., Grover, N., Long, C., Pyle, L., Linder, B., Marcovina, S.M., Harting, J., Shepherd, J., Fan, B., Marquez, L., Sherman, M., Wang, J., Nichols, M., Mayer-Davis, E., Liu, Y., Lima, J., Gidding, S., Puccella, J., Ricketts, E., Danis, R., Domalpally, A., Goulding, A., Neill, S., Vargo, P., Wilfley, D., Aldrich-Rasche, D., Franklin, K., Massmann, C., O'Brien, D., Patterson, J., Tibbs, T., Van Buren, D., Palmert, M., Ratner, R., Dremaine, D., Silverstein, J., Gidding, Samuel S., Bacha, Fida, Bjornstad, Petter, Levitt Katz, Lorraine E., Levitsky, Lynne L., Lynch, Jane, Tryggestad, Jeanie B., Weinstock, Ruth S., El ghormli, Laure, and Lima, Joao A.C.
Published: 2018
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35. PREDICT Plus: development and validation of a prognostic model for early breast cancer that includes HER2

Author: Wishart, GC, Bajdik, CD, Dicks, E, Provenzano, E, Schmidt, MK, Sherman, M, Greenberg, DC, Green, AR, Gelmon, KA, Kosma, V-M, Olson, JE, Beckmann, MW, Winqvist, R, Cross, SS, Severi, G, Huntsman, D, Pylkäs, K, Ellis, I, Nielsen, TO, Giles, G, Blomqvist, C, Fasching, PA, Couch, FJ, Rakha, E, Foulkes, WD, Blows, FM, Bégin, LR, van't Veer, LJ, Southey, M, Nevanlinna, H, Mannermaa, A, Cox, A, Cheang, M, Baglietto, L, Caldas, C, Garcia-Closas, M, and Pharoah, PDP
Subjects: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Breast Cancer, Clinical Research, Cancer, 4.2 Evaluation of markers and technologies, Detection, screening and diagnosis, Adult, Aged, Breast Neoplasms, Cohort Studies, Female, Humans, Middle Aged, Models, Statistical, Prognosis, Proportional Hazards Models, Receptor, ErbB-2, Reproducibility of Results, Young Adult, breast cancer, HER2, prognostic model, Receptor, erbB-2, Public Health and Health Services, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract: Predict (www.predict.nhs.uk) is an online, breast cancer prognostication and treatment benefit tool. The aim of this study was to incorporate the prognostic effect of HER2 status in a new version (Predict+), and to compare its performance with the original Predict and Adjuvant!. The prognostic effect of HER2 status was based on an analysis of data from 10 179 breast cancer patients from 14 studies in the Breast Cancer Association Consortium. The hazard ratio estimates were incorporated into Predict. The validation study was based on 1653 patients with early-stage invasive breast cancer identified from the British Columbia Breast Cancer Outcomes Unit. Predicted overall survival (OS) and breast cancer-specific survival (BCSS) for Predict+, Predict and Adjuvant! were compared with observed outcomes. All three models performed well for both OS and BCSS. Both Predict models provided better BCSS estimates than Adjuvant!. In the subset of patients with HER2-positive tumours, Predict+ performed substantially better than the other two models for both OS and BCSS. Predict+ is the first clinical breast cancer prognostication tool that includes tumour HER2 status. Use of the model might lead to more accurate absolute treatment benefit predictions for individual patients.
Published: 2012

36. Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2

Author: Mulligan, AM, Couch, FJ, Barrowdale, D, Domchek, SM, Eccles, D, Nevanlinna, H, Ramus, SJ, Robson, M, Sherman, M, Spurdle, AB, Wappenschmidt, B, Lee, A, McGuffog, L, Healey, S, Sinilnikova, OM, Janavicius, R, Hansen, TV, Nielsen, FC, Ejlertsen, B, Osorio, A, Muñoz-Repeto, I, Durán, M, Godino, J, Pertesi, M, Benítez, J, Peterlongo, P, Manoukian, S, Peissel, B, Zaffaroni, D, Cattaneo, E, Bonanni, B, Viel, A, Pasini, B, Papi, L, Ottini, L, Savarese, A, Bernard, L, Radice, P, Hamann, U, Verheus, M, Meijers-Heijboer, HEJ, Wijnen, J, Gómez García, EB, Nelen, MR, Kets, CM, Seynaeve, C, Tilanus-Linthorst, MMA, van der Luijt, RB, Os, TV, Rookus, M, Frost, D, Jones, JL, Evans, DG, Lalloo, F, Eeles, R, Izatt, L, Adlard, J, Davidson, R, Cook, J, Donaldson, A, Dorkins, H, Gregory, H, Eason, J, Houghton, C, Barwell, J, Side, LE, McCann, E, Murray, A, Peock, S, Godwin, AK, Schmutzler, RK, Rhiem, K, Engel, C, Meindl, A, Ruehl, I, Arnold, N, Niederacher, D, Sutter, C, Deissler, H, Gadzicki, D, Kast, K, Preisler-Adams, S, Varon-Mateeva, R, Schoenbuchner, I, Fiebig, B, Heinritz, W, Schäfer, D, Gevensleben, H, and Caux-Moncoutier, V
Abstract: Introduction: Previous studies have demonstrated that common breast cancer susceptibility alleles are differentially associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers. It is currently unknown how these alleles are associated with different breast cancer subtypes in BRCA1 and BRCA2 mutation carriers defined by estrogen (ER) or progesterone receptor (PR) status of the tumour.Methods: We used genotype data on up to 11,421 BRCA1 and 7,080 BRCA2 carriers, of whom 4,310 had been affected with breast cancer and had information on either ER or PR status of the tumour, to assess the associations of 12 loci with breast cancer tumour characteristics. Associations were evaluated using a retrospective cohort approach.Results: The results suggested stronger associations with ER-positive breast cancer than ER-negative for 11 loci in both BRCA1 and BRCA2 carriers. Among BRCA1 carriers, single nucleotide polymorphism (SNP) rs2981582 (FGFR2) exhibited the biggest difference based on ER status (per-allele hazard ratio (HR) for ER-positive = 1.35, 95% CI: 1.17 to 1.56 vs HR = 0.91, 95% CI: 0.85 to 0.98 for ER-negative, P-heterogeneity = 6.5 × 10-6). In contrast, SNP rs2046210 at 6q25.1 near ESR1 was primarily associated with ER-negative breast cancer risk for both BRCA1 and BRCA2 carriers. In BRCA2 carriers, SNPs in FGFR2, TOX3, LSP1, SLC4A7/NEK10, 5p12, 2q35, and 1p11.2 were significantly associated with ER-positive but not ER-negative disease. Similar results were observed when differentiating breast cancer cases by PR status.Conclusions: The associations of the 12 SNPs with risk for BRCA1 and BRCA2 carriers differ by ER-positive or ER-negative breast cancer status. The apparent differences in SNP associations between BRCA1 and BRCA2 carriers, and non-carriers, may be explicable by differences in the prevalence of tumour subtypes. As more risk modifying variants are identified, incorporating these associations into breast cancer subtype-specific risk models may improve clinical management for mutation carriers. © 2011 Mulligan et al.; licensee BioMed Central Ltd.
Published: 2011

37. Two Types of Precursor Cells in a Multipotential Hematopoietic Cell Line

Author: Kluger, Yuval, Lian, Zheng, and Weissman, Sherman M.
Published: 2005

38. Heterogeneous Nuclear Ribonucleoprotein C1/C2, MeCP1, and SWI/SNF Form a Chromatin Remodeling Complex at the β-Globin Locus Control Region

Author: Mahajan, Milind C., Narlikar, Geeta J., Kingston, Robert E., and Weissman, Sherman M.
Published: 2005

39. swi1- and swi3-Dependent and Independent Replication Fork Arrest at the Ribosomal DNA of Schizosaccharomyces pombe

Author: Krings, Gregor, Bastia, Deepak, and Weissman, Sherman M.
Published: 2004

40. Lineage Specificity of Gene Expression Patterns

Author: Kluger, Yuval, Tuck, David P., Chang, Joseph T., Nakayama, Yasuhiro, Poddar, Ranjana, Kohya, Naohiko, Lian, Zheng, Ben Nasr, Abdelhakim, Halaban, H. Ruth, Krause, Diane S., Zhang, Xueqing, Newburger, Peter E., and Weissman, Sherman M.
Published: 2004

41. PEDAGOGICAL BASIS OF DEVELOPING OF EDUCATIONAL WEB RESOURCE IN THE DISCIPLINE 'INFORMATICS AND SYSTEMOLOGY' FOR FUTURE ECOLOGIES

Author: Sherman M., Stepanenko N., and Felbush A.
Subjects: computer-information training, didactic principles, future ecologists, informatics and systemology, web-resource of educational appointment, Education
Abstract: Based on the analysis of the information presented in psychological and pedagogical sources, educational and methodological works and the results of own research, a number of contradictions are identified, without which the process of formation of the professional information culture of future ecologists is problematic and uncertain. The main contradictions between the modern social requirements to the level of professional information and technological training of future ecologists and the current state of its organization in state agricultural universities are insufficient in the content of the disciplines «Fundamentals of Informatics and Computer Technology», «Informatics and Systemology», «Information Technologies», «Statistics» the direction needs by which the training of future ecologists is carried out; the actual realization of these disciplines is only a general development function in teaching process, while the realization of tasks of professional computer-information training of future ecologists is secondary task; the interdisciplinary and inter-cycle connections between professionally oriented ecological disciplines and computer science and related disciplines are insufficiently clearly identified and outlined. In order to overcome the above contradictions, we selected the professional-pedagogical principles of creating the content of the discipline «Informatics and Systemology» (principles of professional orientation, professional conformity, integrity, continuity, consistency, logical consistency, pedagogical expediency, information security ensuring, the starting level of mastering by means of information-communication technologies), there is structurization of content of discipline in accordance with the spatio- temporal boundaries, provided by the curriculum of future ecologists professional training, the components of methodological support of teaching of the discipline are developed. The web-resource of educational destination «Informatics and Systemology» was developed and approved, aimed at solving the tasks of computer-information training of future ecologists, containing information of knowledge (expert module), information about the student (student module), information about learning strategies (training module). The description of the functional and modes of using the author's web resource is presented.
Published: 2017
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42. Diagnostic criteria and treatment of neuromyelitis optica spectrum disorders (NMOSD)

Author: Simaniv, T. O., primary, Bakhtiyarova, K. Z., additional, Belova, A. N., additional, Goncharova, Z. A., additional, Sivertseva, S. A., additional, Spirin, N. N., additional, Totolyan, N. A., additional, Trushnikova, T. N., additional, Turova, E. L., additional, Khaibullin, T. I., additional, Sherman, M. A., additional, and Boyko, A. N., additional
Published: 2023
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43. Improved precision with Hologic Apex software

Author: Fan, B, Lewiecki, EM, Sherman, M, Lu, Y, Miller, PD, Genant, HK, and Shepherd, JA
Subjects: Biomedical and Clinical Sciences, Clinical Sciences, Rare Diseases, Musculoskeletal, Absorptiometry, Photon, Aged, Aged, 80 and over, Bone Density, Female, Femur, Femur Neck, Hip Joint, Humans, Lumbar Vertebrae, Middle Aged, Osteoporosis, Postmenopausal, Reproducibility of Results, Software, bone mineral density, dual-energy X-ray absorptiometry, osteoporosis, software version, Biomedical Engineering, Public Health and Health Services, Endocrinology & Metabolism, Clinical sciences, Epidemiology
Abstract: UnlabelledThe precision of Hologic Apex v2.0 analysis software is significantly improved from Hologic Delphi v11.2 software and is comparable to GE Lunar Prodigy v7.5 software. Apex and Delphi precisions were, respectively, 1.0% vs. 1.2% (L1-L4 spine), 1.l % vs. 1.3% (total femur), 1.6% vs. 1.9% (femoral neck), and 0.7% vs. 0.9% (dual total femur).IntroductionPrecision of bone mineral density (BMD) measurements by dual-energy X-ray absorptiometry (DXA) is known to vary by manufacturer, model, and technologist. This study evaluated the precision of three analysis versions: Apex v2.0 and Delphi v11.2 (Hologic, Inc.), and Prodigy v7.5 (GE Healthcare, Inc.) independent of technologist skill.MethodsDuplicate spine and dual hip scans on 90 women were acquired on both Delphi and Prodigy DXA systems at three clinics. BMD measures were converted to standardized BMD (sBMD) units. Precision errors were described as a root-mean-square (RMS) standard deviations and RMS percent coefficients of variation across the population.ResultsApex and Delphi values were highly correlated (r ranged from 0.90 to 0.99). Excluding the right neck, the Apex precision error was found to be 20% to 25% lower than the Delphi (spine: 1.0% versus 1.2% (p < 0.05), total hip: 1.1% versus 1.3% (p < 0.05), right neck: 2.3% versus 2.6% (p > 0.1)). No statistically significant differences were found in the precision error of the Apex and Prodigy (p > 0.05) except for the right neck (2.3% versus 1.8% respectively, p = 0.03).ConclusionThe Apex software has significantly lower precision error compared to Delphi software with similar mean values, and similar precision to that of the Prodigy.
Published: 2008

44. An Approach for Global Scanning of Single Nucleotide Variations

Author: Pan, Xinghua and Weissman, Sherman M.
Published: 2002

45. GATA-1 Binding Sites Mapped in the β-Globin Locus by Using Mammalian ChIp-Chip Analysis

Author: Horak, Christine E., Mahajan, Milind C., Luscombe, Nicholas M., Gerstein, Mark, Weissman, Sherman M., and Snyder, Michael
Published: 2002

46. Correction to: MISC: missing imputation for single-cell RNA sequencing data

Author: Yang, Mary Qu, Weissman, Sherman M., Yang, William, Zhang, Jialing, Canaan, Allon, and Guan, Renchu
Published: 2019
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47. Cardiometabolic outcomes in Kronos Early Estrogen Prevention Study continuation: 14-year follow-up of a hormone therapy trial.

Author: Kantarci, Kejal, Tosakulwong, Nirubol, Lesnick, Timothy G., Kara, Firat, Kendall-Thomas, June, Kapoor, Ekta, Fields, Julie A., James, Taryn T., Lobo, Rogerio A., Manson, JoAnn E., Pal, Lubna, Hammers, Dustin B., Malek-Ahmadi, Michael, Cedars, Marcelle I., Naftolin, Frederick N., Santoro, Nanette, Miller, Virginia M., Harman, Sherman M., Dowling, N. Maritza, and Gleason, Carey E.
Published: 2024
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48. An Overview of Advances in Cell-Based Cancer Immunotherapies Based on the Multiple Immune-Cancer Cell Interactions

Author: Zhang, Jialing, primary, Späth, Stephan S., additional, Weissman, Sherman M., additional, and Katz, Samuel G., additional
Published: 2019
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49. Werner Protein Recruits DNA Polymerase δ to the Nucleolus

Author: Szekely, Anna M., Chen, Yao-Hui, Zhang, Chunyu, Oshima, Junko, and Weissman, Sherman M.
Published: 2000

50. Estimation of Soil Phosphorus Levels in Shrimp Ponds

Author: Ritvo, G., Sherman, M., Lawrence, A. L., and Samocha, T. M.
Published: 2000
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