Search

Your search keyword '"SELA M"' showing total 1,340 results
Start Over Author "SELA M"

Refine your results

more »

more »

more »

more »

more »
1,340 results on '"SELA M"'

13. Copaxone

Author

Teitelbaum, D., primary, Arnon, R., additional, and Sela, M., additional

Published
2007
Full Text
View/download PDF

17. Inhibition of a pancreatic cancer model by cooperative pairs of clinically approved and experimental antibodies

Author

Maron, R., Schechter, B., Nataraj, N. B., Ghosh, S., Romaniello, D., Marrocco, Ilaria, Noronha, A., Carvalho, S., Yarden, Y., Sela, M., Marrocco I. (ORCID:0000-0002-8225-2177), Maron, R., Schechter, B., Nataraj, N. B., Ghosh, S., Romaniello, D., Marrocco, Ilaria, Noronha, A., Carvalho, S., Yarden, Y., Sela, M., and Marrocco I. (ORCID:0000-0002-8225-2177)

Abstract

By year 2025 pancreatic ductal adenocarcinoma (PDAC) is expected to become the second leading cause of cancer related death. However, other than improved chemotherapy and a small molecule inhibitor of the epidermal growth factor receptor (EGFR), no targeted drugs are currently available. Repurposing of approved drugs might offer a rapid solution. We employed an animal PDAC model, expressing a mutant and a wild type form of p53 and KRAS, respectively. Cetuximab, a clinically approved anti-EGFR monoclonal antibody (mAb) weakly inhibited PDAC xenografts, similar to trastuzumab, a mAb against HER2, a co-receptor of EGFR. Because the combination of cetuximab and trastuzumab only moderately enhanced the anti-tumor effects, we combined each with a home-made mAb to the same receptor and identified two cooperative pairs. The pair of trastuzumab and a murine anti-HER2 mAb better than the anti-EGFR pair inhibited PDAC xenografts, although HER2's abundance in our model is 15-fold lower than the level of EGFR. In vitro studies attribute cooperation to forced receptor endocytosis/degradation and inhibition of both DNA synthesis and cell migration. Taken together, our results identify cooperative pairs of anti-PDAC antibodies and highlight potential mechanisms of anti-tumor effects.

Published
2019

27. The Major Histocompatibility Antigens in Various Species : Comparative aspects of major histocompatibility systems

Author

Arber, W., Braun, W., Cramer, F., Haas, R., Henle, W., Hofschneider, P. H., Jerne, N. K., Koldovský, P., Koprowski, H., Maaløe, O., Rott, R., Schweiger, H. G., Sela, M., Syruček, L., Vogt, P. K., Wecker, E., Arber, W., editor, Braun, W., editor, Cramer, F., editor, Haas, R., editor, Henle, W., editor, Hofschneider, P. H., editor, Jerne, N. K., editor, Koldovský, P., editor, Koprowski, H., editor, Maaløe, O., editor, Rott, R., editor, Schweiger, H. G., editor, Sela, M., editor, Syruček, L., editor, Vogt, P. K., editor, and Wecker, E., editor

Published
1970
Full Text
View/download PDF

28. Development of Multi-representation Integrated Learning Media to Understand and Translate the Qur'an in Teaching the Qur'an and Hadith in Elementary Schools

Author

Edhy Rustan, Sela Maria Ningsih, and Fauziah Zainuddin

Subjects
development of learning media, elementary school, multi-representation, Education (General), L7-991
Abstract

Research on the development of media translating the Qur'an was made to determine the need, design, and validity of learning media solving in the learning material of the Qur'an and Hadith in class III MI Dato Sulaiman Palopo. This research method is a research and development (RD) method. The development model used in this development is the ADDIE model (analysis, design, development, implementation, evaluation), but it was only carried out to the development stage in this study. The subject of this research involved 30 students. Data were collected through observation, interviews, and document searches analyzed qualitatively and quantitatively. The needs analysis results show that students need interesting symbols/pictures as learning media and add lesson content well. Learning media is designed by integrating multi-representation in Sempokas media. The feasibility of media teaching materials translating the Qur'an was carried out with the assessment of media experts with a grade level (89.5%), material experts (95.8%), linguists (91.6%), and subject teachers (96, 4%) excellent category. Thus, Sempokas media can be applied in learning to understand and translate Surah Al Ikhlas

Published
2022
Full Text
View/download PDF

29. Antibodies as Carriers for Oncostatic Materials

Author

Arnon, R., Hurwitz, E., Sela, M., Allfrey, V. G., editor, Allgöwer, M., editor, Berenblum, I., editor, Bergel, F., editor, Bernard, J., editor, Bernhard, W., editor, Blokhin, N. N., editor, Bock, H. E., editor, Braun, W., editor, Bucalossi, P., editor, Chaklin, A. V., editor, Chorazy, M., editor, Cunningham, G. J., editor, Della Porta, G., editor, Denoix, P., editor, Dulbecco, R., editor, Eagle, H., editor, Eker, R., editor, Good, R. A., editor, Grabar, P., editor, Harris, R. J. C., editor, Hecker, E., editor, Herbeuval, R., editor, Higginson, J., editor, Hueper, W. C., editor, Isliker, H., editor, Kieler, J., editor, Kirsten, W. H., editor, Klein, G., editor, Koprowski, H., editor, Koss, L. G., editor, Macbeth, R. A., editor, Martz, G., editor, Mathé, G., editor, Mühlbock, O., editor, Old, L. J., editor, Potter, V. R., editor, Sabin, A. B., editor, Sachs, L., editor, Saxén, E. A., editor, Schmidt, C. G., editor, Spiegelman, S., editor, Szybalski, W., editor, Tagnon, H., editor, Tissières, A., editor, Uehlinger, E., editor, Wissler, R. W., editor, Rentchnick, P., editor, Senn, H. J., editor, Mathé, Georges, editor, and Muggia, Franco M., editor

Published
1980
Full Text
View/download PDF

31. Round Table Conference

Author

Pereira, H. G., Biggs, P., Brunell, P., Cockburn, C., Cabasso, V., Gresser, I., Sela, M., Kohn, Alexander, editor, and Klingberg, Marcus A., editor

Published
1972
Full Text
View/download PDF

40. Buchbesprechungen

Author

Lamla, E., Boschke, F., Schultz-Grunow, F., Schäfer, K., Rumberg, B., Mothes, K., Anderer, F. A., Grillmaier, R. E., Sela, M., Neumann, F., Wiechert, R., Jaenicke, L., Böhm, H., Gubler, K., Matthaei, H., Schnepf, E., Linzen, B., Bruckmoser, P., Winchester, J. W., and Preuss, E.

Published
1971
Full Text
View/download PDF

44. LIST OF PARTICIPANTS

Author

TUN-KYI, AUNG, primary, BAJUSZ, S., additional, BEYERMAN, H.C., additional, BEZAS, B., additional, BODANSZKY, M., additional, BOISSONNAS, R.A., additional, BOTVINIK, M.M., additional, BRENNER, M., additional, BRICAS, E., additional, BRUCKNER, V., additional, COSMATOS, A., additional, COSTOPANAGIOTIS, A., additional, CRAIG, L.C., additional, DANE, E., additional, DETERMANN, H., additional, DILARIS, I., additional, DRABAREK, S., additional, ELLIOTT, D.F., additional, FAWCETT, C.P., additional, GHELIS, N., additional, GREVEN, H.M., additional, GUTTMANN, ST., additional, HARTMANN, A., additional, HOFER, W., additional, ISELIN, B.M., additional, IVANOV, V.T., additional, JOŠT, K., additional, KENNER, G.W., additional, KERLING, K.E.TH., additional, KISFALUDY, L., additional, LAW, H.D., additional, LEDERER, E., additional, MANTZOS, H., additional, MEDZIHRADSZKY, K., additional, MEIENHOFER, J., additional, MORLEY, J.S., additional, NESVADBA, H., additional, NIVARD, R.J.F., additional, OKUDA, T., additional, PATCHORNIK, A., additional, PHOTAKI, I., additional, PROX, A., additional, RIDGE, B., additional, ROCCHI, R., additional, RUDINGER, J., additional, RYDON, H.N., additional, SCHNABEL, E., additional, SCOFFONE, E., additional, SCHRÖDER, E., additional, SCHWYZER, R., additional, SELA, M., additional, SHEEHAN, J.C., additional, SHEMYAKIN, M.M., additional, SIEBER, P., additional, SIEDEL, W., additional, SMYTH, D.G., additional, SOUCHLERIS, I., additional, STELAKATOS, G.C., additional, STUDER, R.O., additional, TASCHNER, E., additional, TESSER, G.I., additional, THEODOROPOULOS, D.M., additional, WADE, R., additional, WALEY, S.G., additional, WEYGAND, F., additional, WIELAND, TH., additional, WITKOP, B., additional, WÜNSCH, E., additional, YOUNG, G.T., additional, ZERVAS, L., additional, ZIOUDROU, C., additional, ZIPP, O., additional, and ZUBER, H., additional

Published
1966
Full Text
View/download PDF

47. Pengembangan LKPD Berbasis Discovery Learning Berbantuan Software Tracker Untuk Meningkatkan Pemahaman Konsep Peserta Didik Kelas X di SMA Sriguna Palembang Pada Materi GHS

Author

Sela Melinia, Patricia H.M Lubis, and Sulistiawati Sulistiawati

Subjects
LKPD, Discovery Learning, Tracker Software, Physics, QC1-999, Theory and practice of education, LB5-3640
Abstract

This study aims to produce LKPD products based on Discovery Learning assisted by Software Tracker to improve understanding of the concepts of class X students at SMA Sriguna Palembang that are valid, practical, and have a potential effect on understanding concepts. This study uses a modified Rowntree development model based on formative evaluation. The subjects used in this research are students of class X IPA 2 SMA Sriguna Palembang, as many as 34 students. This research produces: 1) LKPD based on Discovery Learning assisted by Software Tracker which is valid. Based on the research results, the average results of material aspects are 81.33%, learning design aspects are 80% and language aspects are 80%, 2) practicality test results in the one to one stage obtained an average of 93% with a very practical category, 3) the results of the practicality test at the small group stage obtained an average of 87.62% with a very practical category, 4) the field test stage obtained the highest N-Gain value by 64.70% in the high category and the lowest N-Gain value is 35.29% in the medium category. ÃÂ

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results