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517 results on '"SCOGGINS, B. A."'

2. Stress, Acth, and Hypertension

Author

Denton, D. A., Coghlan, J. P., McKinley, M., Nelson, J., Scoggins, B. A., Weisinger, R., Whitworth, J. A., Villarreal, Herman, editor, and Sambhi, Mohinder P., editor

Published
1984
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19. © RENAL AUTOTRANSPLANTATION IN SHEEP -- PREPARATION AND PHYSIOLOGY.

Author

Wright, R. D., McDougall, J. G., Coghlan, J. P., Denton, D. A., Hardy, K. J., Potocnik, S. J., and Scoggins, B. A.

Abstract

The article describes the autotransplantation of the right kidney to the neck region with anastomoses of renal blood vessels to the carotid artery and jugular vein and of the ureter to the explanted parotid duct in sheep. The response of the transplanted kidney to simple experimental manipulations was carried out in order to assess its physiological functions as base lines for extended use in physiological and pharmacological investigations presents a novel procedure for renal autotransplantation in sheep. The operative procedure involved two preliminary operations for preparation of carotid artery and jugular vein loops and of a Wright-type parotid fistula.

Published
1982
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20. Cardiac effects of different tricyclic antidepressant drugs.

Author

Burrows, G. D., Vohra, J., Hunt, D., Sloman, J. G., Scoggins, B. A., Davies, Brian, and Davies, B

Subjects
ANTIDEPRESSANTS, PHARMACODYNAMICS, HEART diseases, HEART conduction system, HEART beat, DEPRESSED persons
Abstract

The effects of tricyclic antidepressants on the heart are reviewed. Statistically significant increases in heart rate and in atrioventricular conduction times were found following the administration of tricyclic drugs to 32 depressed patients. The method of His bundle electrocardiography was used to study atrioventricular conduction in ambulant patients and in patients admitted after an overdose of tricyclic antidepressant drugs. Distal conduction defects were frequently found in patients following tricyclic overdosage, but these were not seen with doxepin overdosage. Impaired distal conduction was also found in occasional patients on therapeutic doses of tricyclic drugs. Some animal experiments giving similar results to the above clinical findings are also described. The clinical implications of these findings are discussed. [ABSTRACT FROM AUTHOR]

Published
1976
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21. Concerning the independence of the basis of hypertension due to ACTH or renovascular constriction1.

Author

SHULKES, A. A., COGHLAN, J. P., DENTON, D. A., FAN, J. S. K., and SCOGGINS, B. A.

Abstract

Administration of ACTH to four sheep with chronic renovascular hypertension resulted in an increase in blood pressure which was at least as high as that described in normotensive sheep and could be completely accounted for by an increase in cardiac output. [ABSTRACT FROM PUBLISHER]

Published
1976

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