43 results on '"SCHECHTMAN Leonard"'
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2. Rodent cell transformation assays—A brief historical perspective
3. Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics
4. ECVAM prevalidation study on in vitro cell transformation assays: General outline and conclusions of the study
5. Guidance on Good Cell Culture Practice : A Report of the Second ECVAM Task Force on Good Cell Culture Practice
6. Biological Activity of Tobacco Smoke and Tobacco Smoke-Related Chemicals
7. Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs
8. ICH Guidances on Genotoxicity and Carcinogenicity
9. Involvement of Radicals in Chemical Carcinogenesis
10. Chemical enhancement of simian adenovirus SA7 oncogenic transformation of Syrian golden hamster embryo (SHE) cells
11. JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for the detection of genotoxic carcinogens: I. Summary of pre-validation study results
12. JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results
13. The JaCVAM international validation study on the in vivo comet assay: Selection of test chemicals
14. The Principles of Weight of Evidence Validation of Test Methods and Testing Strategies: The Report and Recommendations of ECVAM Workshop 58a
15. Validation of Toxicogenomics-Based Test Systems:ECVAM-ICCVAM/NICEATM Considerations for Regulatory Use
16. Guidance on Good Cell Culture Practice
17. Points of Reference in the Validation Process
18. The Principles of Weight of Evidence Validation of Test Methods and Testing Strategies
19. Guidance on Good Cell Culture Practice
20. The FDA's Regulatory Role in the ICCVAM Process
21. Strategy for genotoxicity testing and stratification of genotoxicity test results—report on initial activities of the IWGT Expert Group
22. ECVAM-ICCVAM: Prospects for Future Collaboration
23. The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM): A Review of the ICCVAM Test Method Evaluation Process and Current International Collaborations with the European Centre for the Validation of Alternative Methods (ECVAM)
24. Implementation of the 3Rs (Refinement, Reduction, and Replacement): Validation and Regulatory Acceptance Considerations for Alternative Toxicological Test Methods
25. The International Symposium on Regulatory Testing and Animal Welfare: Recommendations on Best Scientific Practices for Animal Care in Regulatory Toxicology
26. The Safety Assessment Process—Setting the Scene: An FDA Perspective
27. Novel Pyrogen Tests Based on the Human Fever Reaction
28. Evaluation of the rodent micronucleus assay by a 28‐day treatment protocol: Summary of the 13th Collaborative Study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Environmental Mutagen Society of Japan (JEMS)–Mammalian Mutagenicity Study Group (MMS)
29. ICH-Harmonised guidances on genotoxicity testing of pharmaceuticals: evolution, reasoning and impact
30. O XIX A.1 ICH harmonisation of genotoxicity testing for pharmaceuticals; consequences for industry and regulatory bodies
31. International workshop on mouse lymphoma assay testing practices and data interpretations: Portland, Oregon, may 7,1994
32. Induction of mutagenesis and transformation in BALB/c‐3T3 clone A31‐1 cells by diverse chemical carcinogens
33. Guidance on Good Cell Culture Practice.
34. Morphological transformation of BALB/3T3 cells by various procarcinogens in the presence of a rat liver S-9 activation system.
35. Effect of 3-aminobenzamide on the induction of toxicity and transformation by ethyl methanesulfonate and methylcholanthrene in BALB/3T3 cells.
36. Interlaboratory evaluation of the c3h/10t1/2 cell transformation assay.
37. Measurement of cytochrome P-450 dependent dealkylation of alkoxy-phenoxazones in hepatic S9s and hepatocyte homogenates: effects of dicumarol
38. Cell transformation by chemical agents — A review and analysis of the literature
39. The JaCVAM international validation study on the in vivo comet assay: Selection of test chemicals.
40. JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for the detection of genotoxic carcinogens: I. Summary of pre-validation study results.
41. JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results.
42. ECVAM prevalidation of three cell transformation assays.
43. The international symposium on regulatory testing and animal welfare: recommendations on best scientific practices for subchronic/chronic toxicity and carcinogenicity testing.
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