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306 results on '"SCHANDELMAIER, P."'

3. Migräne im Kindes- und Jugendalter – Ausblick auf innovative Behandlungsansätze im Rahmen multimodaler Therapiekonzepte

Author

Bonfert, Michaela Veronika, Börner, Corinna, Gerstl, Lucia, Hannibal, Iris, Mathonia, Nina, Huß, Kristina, Rahmsdorf, Birte, Kainz, Christina, Klose, Birgit, Koenig, Helene, Urban, Giada, Schandelmaier, Paul, Renner, Tabea, Albers, Lucia, Krieg, Sandro Manuel, Sollmann, Nico, Heinen, Florian, and Landgraf, Mirjam Natascha

Published
2020
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5. Proton-Pump Inhibitors to Prevent Gastrointestinal Bleeding -- An Updated Meta-Analysis.

Author

Ying Wang, Parpia, Sameer, Long Ge, Heels-Ansdell, Diane, Honghao Lai, Esfahani, Meisam Abdar, Bei Pan, Alhazzani, Waleed, Schandelmaier, Stefan, Lauzier, Francois, Arabi, Yaseen, Barletta, Jeffrey, Deane, Adam, Finfer, Simon, Williamson, David, Kanji, Salmaan, Møller, Morten H., Perner, Anders, Krag, Mette, and Young, Paul J.

Subjects
PATIENT safety, GASTROINTESTINAL hemorrhage, PEPTIC ulcer, TREATMENT effectiveness, META-analysis, SEVERITY of illness index, RELATIVE medical risk, PRE-exposure prophylaxis, PROTON pump inhibitors, CONFIDENCE intervals, CRITICALLY ill patient psychology
Abstract

Background: The goal of this systematic review was to examine the efficacy and safety of proton-pump inhibitors for stress ulcer prophylaxis in critically ill patients. Methods: We included randomized trials comparing proton-pump inhibitors versus placebo or no prophylaxis in critically ill adults, performed meta-analyses, and assessed certainty of evidence using the Grading of Recommendations, Assessment, Development, and Evaluations approach. To explore the effect of proton-pump inhibitors on mortality based on disease severity, a subgroup analysis was conducted combining within-trial subgroup data from the two largest trials and assessed credibility using the Instrument for Assessing the Credibility of Effect Modification Analyses. Results: Twelve trials that enrolled 9533 patients were included. Proton-pump inhibitors were associated with a reduced incidence of clinically important upper gastrointestinal bleeding (relative risk [RR], 0.51 [95% confidence interval (CI), 0.34 to 0.76]; high certainty evidence). Proton-pump inhibitors may have little or no effect on mortality (RR, 0.99 [95% CI, 0.93 to 1.05]; low certainty). Within-trial subgroup analysis with intermediate credibility suggested that the effect of proton-pump inhibitors on mortality may differ based on disease severity. Subgroup results raise the possibility that proton-pump inhibitors may decrease 90-day mortality in less severely ill patients (RR, 0.89; 95% CI, 0.80 to 0.98) and may increase mortality in more severely ill patients (RR, 1.08; 95% CI, 0.96 to 1.20]. Proton-pump inhibitors may have no effect on pneumonia and little or no effect on Clostridioides difficile infection (low certainty). Conclusions: High certainty evidence supports the association of proton-pump inhibitors with decreased upper gastrointestinal bleeding. Proton-pump inhibitors may have little or no effect on mortality, although a decrease in mortality in less severely ill patients and an increase in mortality in more severely ill patients remain possible. (PROSPERO number CRD42023461695.) [ABSTRACT FROM AUTHOR]

Published
2024
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6. Rationale and design of repeated cross-sectional studies to evaluate the reporting quality of trial protocols: the Adherence to SPIrit REcommendations (ASPIRE) study and associated projects

Author

Gryaznov, Dmitry, Odutayo, Ayodele, von Niederhäusern, Belinda, Speich, Benjamin, Kasenda, Benjamin, Ojeda-Ruiz, Elena, Blümle, Anette, Schandelmaier, Stefan, Mertz, Dominik, Tomonaga, Yuki, Amstutz, Alain, Pauli-Magnus, Christiane, Gloy, Viktoria, Bischoff, Karin, Wollmann, Katharina, Rehner, Laura, Lohner, Szimonetta, Meerpohl, Joerg J., Nordmann, Alain, Klatte, Katharina, Ghosh, Nilabh, Heravi, Ala Taji, Wong, Jacqueline, Chow, Ngai, Hong, Patrick Jiho, Cord, Kimberly Mc, Sricharoenchai, Sirintip, Busse, Jason W., Agarwal, Arnav, Saccilotto, Ramon, Schwenkglenks, Matthias, Moffa, Giusi, Hemkens, Lars G., Hopewell, Sally, von Elm, Erik, and Briel, Matthias

Published
2020
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7. Prediction of RECRUITment In randomized clinical Trials (RECRUIT-IT)—rationale and design for an international collaborative study

Author

Kasenda, Benjamin, Liu, Junhao, Jiang, Yu, Gajewski, Byron, Wu, Cen, von Elm, Erik, Schandelmaier, Stefan, Moffa, Giusi, Trelle, Sven, Schmitt, Andreas Michael, Herbrand, Amanda K., Gloy, Viktoria, Speich, Benjamin, Hopewell, Sally, Hemkens, Lars G., Sluka, Constantin, McGill, Kris, Meade, Maureen, Cook, Deborah, Lamontagne, Francois, Tréluyer, Jean-Marc, Haidich, Anna-Bettina, Ioannidis, John P. A., Treweek, Shaun, and Briel, Matthias

Published
2020
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9. Online Studies on Variation in Orthopedic Surgery: Computed Tomography in MPEG4 Versus DICOM Format

Author

Mellema, Jos J., Mallee, Wouter H., Guitton, Thierry G., van Dijk, C. Niek, Ring, David, Doornberg, Job N., Babis, G. C., Jeray, K. J., Prayson, M. J., Pesantez, R., Acacio, R., Verbeek, D. O., Melvanki, P., Kreis, B. E., Mehta, S., Meylaerts, S., Wojtek, S., Yeap, E. J., Haapasalo, H., Kristan, A., Coles, C., Marsh, J. L., Mormino, M., Menon, M., Tyllianakis, M., Schandelmaier, P., Jenkinson, R. J., Neuhaus, V., Shahriar, C. M. H., Belangero, W. D., Kannan, S. G., Leonidovich, G. M., Davenport, J. H., Kabir, K., Althausen, P. L., Weil, Y., Toom, A., Sa da Costa, D., Lijoi, F., Koukoulias, N. E., Manidakis, N., Van den Bogaert, M., Patczai, B., Grauls, A., Kurup, H., van den Bekerom, M. P., Lansdaal, J. R., Vale, M., Ousema, P., Barquet, A., Cross, B. J., Broekhuyse, H., Haverkamp, D., Merchant, M., Harvey, E., Pemovska, E. Stojkovska, Frihagen, F., Seibert, F. J., Garnavos, C., van der Heide, H., Villamizar, H. A., Harris, I., Borris, L. C., Brink, O., Brink, P. R. G., Choudhari, P., Swiontkowski, M., Mittlmeier, T., Tosounidis, T., van Rensen, I., Martinelli, N., Park, D. H., Lasanianos, N., Vide, J., Engvall, A., Zura, R. D., Jubel, A., Kawaguchi, A., Goost, H., Bishop, J., Mica, L., Pirpiris, M., van Helden, S. H., Bouaicha, S., Schepers, T., Havliček, T., Giordano, V., and Science of Variation Group & Traumaplatform Study Collaborative

Published
2017
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10. The Interobserver Reliability of Grading of Distal Radius Volar Plate Prominence

Author

Crijns, Tom J., primary, Merkel, Patrick, additional, Kortlever, Joost T.P., additional, Wagner, K. John, additional, Ring, David, additional, Vagner, Gregg, additional, Teunis, Teun, additional, Akabudike, N.M., additional, Apard, T., additional, Bafus, B.T., additional, Ballas, E.G., additional, Bamberger, H.B., additional, Baxamusa, T., additional, Begue, T.C., additional, Belangero, W.D., additional, Benhaim, P., additional, Biert, J., additional, Blazar, P., additional, Bloemers, F.W., additional, Borris, L.C., additional, Brink, O., additional, Brubacher, J.W., additional, Buckley, R., additional, Calcagni, M., additional, Calfee, R.P., additional, Campbell, S.T., additional, Chepla, K.J., additional, Choudhari, P., additional, Conflitti, J.M., additional, Coomber, R., additional, de Bedout, R., additional, Debeij, J., additional, DeCoster, T., additional, DeSilva, G., additional, Domenech, J., additional, Draeger, R.W., additional, Dwyer, C.L., additional, Elias, N., additional, Erickson, J.M., additional, Evans, P.J., additional, Farr, S., additional, Fernandes, C.H., additional, Fricker, R., additional, Garnavos, C., additional, Gilbert, R.S., additional, Giordano, V., additional, Goost, H., additional, Gosens, T., additional, Guitton, T.G., additional, Hammert, W.C., additional, Havlicek, T., additional, Hearon, B.F., additional, Henry, S.L., additional, Hobby, J.L., additional, Hodel, S., additional, Hofmeister, E.P., additional, Huang, J.I., additional, Jebson, P., additional, Jenkinson, R., additional, Jeray, K., additional, Kabir, K., additional, Kanakaris, N.K., additional, Kaplan, F.T.D., additional, Kennedy, S.A., additional, Klostermann, C., additional, Knobe, M., additional, Kraan, G.A., additional, Kristan, A., additional, Lane, L.B., additional, Lawson McLean, A., additional, Lightdale-Miric, N., additional, Metzger, C.L., additional, Mica, L., additional, Miranda, G.V., additional, Mirck, B., additional, Mitchell, S., additional, Mittlmeier, T., additional, Moreno-Serrano, C.L., additional, Nancollas, M.P., additional, Ortiz, J.A., additional, Peters, A., additional, Pianka, G., additional, Pirpiris, M., additional, Poelhekke, L.M.S.J., additional, Prkic, A., additional, Prommersberger, K.J., additional, Raven, E.E.J., additional, Rizzo, M., additional, Rodner, C., additional, Rodríguez Roiz, J.M., additional, Rohde, R.S., additional, Romero, C.J., additional, Sandoval, J., additional, Schandelmaier, P., additional, Schep, N.W.L., additional, Schepers, T., additional, Schiffer, G., additional, Seibert, F.J., additional, Shafritz, A.B., additional, Shortt, N.L., additional, Siff, T., additional, Spitler, C.A., additional, Spoor, A.B., additional, Streubel, P., additional, Swiontkowski, M., additional, Talbot, M., additional, Taras, J.S., additional, Tolo, E.T., additional, Tyllianakis, M., additional, van Demark, R.E., additional, van der Heide, H., additional, van der Plaat, L.W., additional, van der Pluijm, M., additional, van Eerten, P.V., additional, Verbeek, D.O., additional, Vochteloo, A.J., additional, Walbeehm, R.P., additional, Wascher, D.C., additional, Wills, B.P.D., additional, Wint, J., additional, Zaidenberg, E.E., additional, and Zeltser, D.W., additional

Published
2022
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11. Distale Femurfrakturen

Author

Schandelmaier, P., Gössling, T., Partenheimer, A., Krettek, C., Bauch, J., editor, Betzler, M., editor, and Lobenhoffer, P., editor

Published
2004
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12. Alternative Osteosynthesetechniken bei offenen Frakturen

Author

Szyszkowitz, R., Grechenig, W., Josten, C., Krettek, C., Schandelmaier, P., Rudolf, J., Könemann, B., Tscherne, H., Braun, W., Mayr, E., Rüter, A., Jukema, G. N., Settner, M., Böhm, H.-J., Hierholzer, G., Siebert, C. H., Höfler, H. R., Hansis, M., Schmittenbecher, P. P., Dietz, H.-G., Hartel, W., editor, and Hierholzer, G.

Published
1995
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20. Effects of remdesivir in patients hospitalised with COVID-19: a systematic review and individual patient data meta-analysis of randomised controlled trials

Author

Amstutz, Alain, Speich, Benjamin, Mentré, France, Rueegg, Corina Silvia, Belhadi, Drifa, Assoumou, Lambert, Burdet, Charles, Murthy, Srinivas, Dodd, Lori Elizabeth, Wang, Yeming, Tikkinen, Kari A O, Ader, Florence, Hites, Maya, Bouscambert, Maude, Trabaud, Mary Anne, Fralick, Mike, Lee, Todd C, Pinto, Ruxandra, Barratt-Due, Andreas, Lund-Johansen, Fridtjof, Müller, Fredrik, Nevalainen, Olli P O, Cao, Bin, Bonnett, Tyler, Griessbach, Alexandra, Taji Heravi, Ala, Schönenberger, Christof, Janiaud, Perrine, Werlen, Laura, Aghlmandi, Soheila, Schandelmaier, Stefan, Yazdanpanah, Yazdan, Costagliola, Dominique, Olsen, Inge Christoffer, and Briel, Matthias

Abstract

Interpretation of the evidence from randomised controlled trials (RCTs) of remdesivir in patients treated in hospital for COVID-19 is conflicting. We aimed to assess the benefits and harms of remdesivir compared with placebo or usual care in these patients, and whether treatment effects differed between prespecified patient subgroups.

Published
2023
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23. Robustness of reported postacute health outcomes in children with SARS-CoV-2 infection: a systematic review

Author

Hirt, Julian, Janiaud, Perrine, Gloy, Viktoria Luise, Schandelmaier, Stefan, Pereira, Tiago V, Contopoulos-Ioannidis, Despina, Goodman, Steven N, Ioannidis, John, Munkholm, Klaus, and Hemkens, Lars G

Abstract

ObjectiveTo systematically assess the robustness of reported postacute SARS-CoV-2 infection health outcomes in children.MethodsA search on PubMed and Web of Science was conducted to identify studies published up to 22 January 2022 that reported on postacute SARS-CoV-2 infection health outcomes in children (<18 years) with follow-up of ≥2 months since detection of infection or ≥1 month since recovery from acute illness. We assessed the consideration of confounding bias and causality, as well as the risk of bias.Results21 studies including 81 896 children reported up to 97 symptoms with follow-up periods of 2.0–11.5 months. Fifteen studies had no control group. The reported proportion of children with post-COVID syndrome was between 0% and 66.5% in children with SARS-CoV-2 infection (n=16 986) and between 2.0% and 53.3% in children without SARS-CoV-2 infection (n=64 910). Only two studies made a clear causal interpretation of an association between SARS-CoV-2 infection and the main outcome of ‘post-COVID syndrome’ and provided recommendations regarding prevention measures. The robustness of all 21 studies was seriously limited due to an overall critical risk of bias.ConclusionsThe robustness of reported postacute SARS-CoV-2 infection health outcomes in children is seriously limited, at least in all the published articles we could identify. None of the studies provided evidence with reasonable certainty on whether SARS-CoV-2 infection has an impact on postacute health outcomes, let alone to what extent. Children and their families urgently need much more reliable and methodologically robust evidence to address their concerns and improve care.

Published
2023
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44. Proximale Tibiafrakturen und Begleitverletzungen

Author

Rommens, P. M., primary, Wentzensen, A., additional, Gruner, A., additional, Hockertz, Th., additional, Kleine, B., additional, Reilmann, H., additional, Schütz, M., additional, Kääb, M., additional, Schmeling, A., additional, Raschke, M., additional, Haas, N. P., additional, Mothes, K. U., additional, Gonschorek, O., additional, Hertel, V., additional, Josten, C., additional, Roth, V., additional, Babst, R., additional, Gösling, T., additional, Schandelmaier, P., additional, Marti, A., additional, Krettek, C., additional, Kasten, P., additional, Lahoda, L.-U., additional, Kutscha-Lissberg, F., additional, Kollig, E., additional, and Muhr, G., additional

Published
2001
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45. Video II

Author

Blum, J., primary, Rommens, P. M., additional, Raphael, S., additional, Baacke, M., additional, Könemann, B., additional, Schandelmaier, P., additional, Partenheimer, A., additional, Krettek, C., additional, Hofmann, C., additional, Gotzen, L., additional, and Lobenhoffer, P., additional

Published
2000
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46. Postersession VI-Soft Tissue/Knorpel

Author

Schwarz, W., primary, Friemert, B., additional, Oberländer, Y., additional, Danz, B., additional, Bähren, W., additional, Gerngroß, H., additional, Maier, G. M., additional, Weindel, S., additional, Müller-Rath, R., additional, Bolte, S., additional, Maier, V., additional, Mommsen, U., additional, Baacke, M. G., additional, Stiletto, R., additional, Leppek, R., additional, Bäthis, H., additional, Tingart, M., additional, Bouillon, B., additional, Gaitzsch, A., additional, Bogosi, T., additional, Merényi, G., additional, Atanaszov, T., additional, Schubert, S., additional, Piatek, S., additional, Westphal, T., additional, Bürger, T., additional, Winckler, S., additional, Scola, E., additional, Simanski, C., additional, Koch-Epping, G., additional, Tiling, T., additional, Rühmann, O., additional, Wirth, C., additional, Gossé, F., additional, Schmolke, S., additional, Dumont, C., additional, Stanković, P., additional, Fuchs, M., additional, Stürmer, K. M., additional, Jezussek, D., additional, Kleine, L., additional, Weber, O., additional, Schmidgen, A., additional, Wentzensen, A., additional, Hinsche, A. F., additional, Joseph, J., additional, Giannoudis, P. V., additional, Matthews, S. J., additional, Smith, R. M., additional, Mueller, J. E., additional, Ilchmann, T., additional, Lowatscheff, T., additional, Sterk, J., additional, Völker, H. U., additional, Willy, C., additional, Manak, P., additional, Drac, P., additional, Frebel, T., additional, Leidinger, B., additional, Joist, A., additional, Joosten, U., additional, Klever, P., additional, Siekmann, U. P. F., additional, Erli, H. J., additional, Haltern, C., additional, Rossaint, R., additional, Paar, O., additional, Niebauer, T., additional, Gehr, J., additional, Friedl, W., additional, Tóth, L., additional, Kovács, J., additional, Fierpasz, F., additional, Dósa, G., additional, Radebold, T., additional, Hensel, J., additional, Bischoff, M., additional, Grabensee, R., additional, Schmelz, A., additional, Kinzl, L., additional, Huber, F., additional, Scherer, M. A., additional, Metak, G., additional, v. Gumppenberg, S., additional, Fuchs, T., additional, Schmidmaier, G., additional, Hoffmann, J. E., additional, Raschke, M., additional, Betthäuser, A., additional, Raabe, K., additional, Hille, E., additional, Bickert, T., additional, Folgmann, J., additional, Kurten, K., additional, Kühne, C., additional, Klinger, O., additional, Gotzen, L., additional, Schnabel, M., additional, Wenski, M., additional, von Garrel, T., additional, Förtsch, M., additional, Prymka, M., additional, Zeller, R., additional, Schürmann, M., additional, Zaspel, J., additional, Wipfel, A., additional, Gradl, G., additional, Herzog, C., additional, Bauer, M., additional, Clemens, M. G., additional, Marzi, I., additional, Lehmann, W., additional, Linhart, W., additional, Schilling, A. F., additional, Schwarz, K., additional, Epple, M., additional, Rueger, J. M., additional, Blum, J., additional, Högner, M., additional, Baumgart, F., additional, Rommens, P. M., additional, Pszolla, M., additional, Keppler, P., additional, Strecker, W., additional, Dollriess, C., additional, Kollig, E., additional, Hopf, F., additional, Muhr, G., additional, Henke, T., additional, Gruber, S., additional, Schmidt, J., additional, Winker, K. H., additional, Degreif, J., additional, Müller, L. P., additional, Rudig, L., additional, Ewert, A., additional, Scheller, A., additional, Voigt, C., additional, Rahmanzadeh, R., additional, Kettler, M., additional, Trageiser, S., additional, Baumgart, R., additional, Mutschler, W., additional, Frosch, K.-H., additional, Schmid, A., additional, Altenvoerde, G., additional, Schiefer, U. R., additional, Nijs, J. B., additional, Broos, P. L. O., additional, Pape, D., additional, Fritsch, E., additional, Adam, A., additional, Kohn, D., additional, Thannheimer, A., additional, Ketterl, R., additional, Brüner, S., additional, Wittemann, M., additional, Karle, B., additional, Germann, G., additional, Gänsslen, A., additional, Pohlemann, T., additional, Pape, H. C., additional, Tscherne, H., additional, Grotz, M., additional, Kaufmann, U., additional, Danelia, N., additional, Wippermann, B. W., additional, Mahlke, L., additional, Winny, M., additional, Pape, H.-C., additional, Gonschorek, O., additional, Rüttinger, D., additional, Hofmann, G. O., additional, Bühren, V., additional, Liener, U. C., additional, Brückner, U. B., additional, Steinbach, G., additional, Gebhard, F., additional, Rummeny, M., additional, Fell, M., additional, Kottkamp, H. W., additional, Meißer, A., additional, Sarkar, M., additional, Billharz, E., additional, Andermahr, J., additional, Helling, H. J., additional, Hensler, T., additional, Greb, A., additional, Neugebauer, E., additional, Rehm, K. E., additional, Weinberg, A.-M., additional, Hawi, R., additional, Jablonski, M., additional, Hofmann, H., additional, Zdichavsky, M., additional, Bastian, L., additional, Knop, C., additional, Lange, U., additional, Lotz, J., additional, Blauth, M., additional, Grün, O., additional, Gössling, T., additional, Müller-Heine, A., additional, Schandelmaier, P., additional, Halder, A., additional, Drischmann, S., additional, Ludwig, S., additional, Kreusch-Brinker, R., additional, Karl, A., additional, Stumpf, M., additional, Jonas, F., additional, Neumann, C., additional, Nerlich, M., additional, Ohnsorge, J., additional, Wirtz, D.-C., additional, Birnbaum, K., additional, Heller, K.-D., additional, Langer, M., additional, Ziring, E., additional, Ishaque, B., additional, Petermann, J., additional, Szabo, Z., additional, Barany, I., additional, Chantes, M. E., additional, Mastrokalos, D., additional, Tibesku, C. O., additional, Pässler, H. H., additional, Jung, D., additional, Matussek, V., additional, Habermeyer, P., additional, Meier, R., additional, Thermann, H., additional, Schratt, H. E., additional, van Griensven, M., additional, van Schoonhoven, J., additional, Djalal, T., additional, Freitag, R., additional, Klüppel, D., additional, Hillrichs, B., additional, Echtermeyer, V., additional, Marlovits, S., additional, Stocker, R., additional, Vécsei, V., additional, Schabus, R. S., additional, Ankin, N. L., additional, Ankin, L. N., additional, Schmeling, A., additional, Kääb, M., additional, Wieling, R., additional, Ito, K., additional, Schütz, M., additional, Trentz, O. A., additional, Uhlschmid, G. K., additional, Weber, S., additional, Graser, C., additional, Fichtel, I., additional, Schlegel, J., additional, Hessmann, M. H., additional, Geiger, F., additional, Wendler, C., additional, Forkl, H., additional, Andress, H. J., additional, Brüning, R., additional, Grubwinkler, M., additional, Lob, G., additional, Weiβer, C., additional, Wagner, R., additional, Weckbach, A., additional, Schädel-Höpfner, M., additional, Giannadakis, K., additional, Fröhlich, J., additional, Dietrich, A., additional, Lill, H., additional, Engel, T., additional, Josten, C., additional, Richter, K., additional, Verheyden, P., additional, Martin, U., additional, and Beckert, M., additional

Published
2000
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