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20. Research conference summary from the 2014 International Task Force on ATP1A3-Related Disorders

Author

Rosewich, Hendrik, Sweney, Matthew T, DeBrosse, Suzanne, Ess, Kevin, Ozelius, Laurie, Andermann, Eva, Andermann, Frederick, Andrasco, Gene, Belgrade, Alice, Brashear, Allison, Ciccodicola, Sharon, Egan, Lynn, George, Alfred L, Lewelt, Aga, Magelby, Joshua, Merida, Mario, Newcomb, Tara, Platt, Vicky, Poncelin, Dominic, Reyna, Sandra, Sasaki, Masayuki, Sotero de Menezes, Marcio, Sweadner, Kathleen, Viollet, Louis, Zupanc, Mary, Silver, Kenneth, and Swoboda, Kathryn

Subjects
Reproductive Medicine, Biomedical and Clinical Sciences, Prevention, Pediatric, Neurosciences, Neurodegenerative, Rare Diseases, Clinical Research, Genetics, Clinical sciences
Abstract

ObjectiveATP1A3-related neurologic disorders encompass a broad range of phenotypes that extend well beyond initial phenotypic criteria associated with alternating hemiplegia of childhood (AHC) and rapid-onset dystonia parkinsonism.MethodsIn 2014, the Alternating Hemiplegia of Childhood Foundation hosted a multidisciplinary workshop intended to address fundamental challenges surrounding the diagnosis and management of individuals with ATP1A3-related disorders.ResultsWorkshop attendees were charged with the following: (1) to achieve consensus on expanded diagnostic criteria to facilitate the identification of additional patients, intended to supplement existing syndrome-specific diagnostic paradigms; (2) to standardize definitions for the broad range of paroxysmal manifestations associated with AHC to disseminate to families; (3) to create clinical recommendations for common recurrent issues facing families and medical care providers; (4) to review data related to the death of individuals in the Alternating Hemiplegia of Childhood Foundation database to guide future efforts in identifying at-risk subjects and potential preventative measures; and (5) to identify critical gaps where we most need to focus national and international research efforts.ConclusionsThis report summarizes recommendations of the workshop committee, highlighting the key phenotypic features to facilitate the diagnosis of possible ATP1A3 mutations, providing recommendations for genetic testing, and outlining initial acute management for common recurrent clinical conditions, including epilepsy.

Published
2017

26. Clinical practice guidelines for high-resolution breast PET, 2019 edition

Author

Satoh, Yoko, Kawamoto, Masami, Kubota, Kazunori, Murakami, Koji, Hosono, Makoto, Senda, Michio, Sasaki, Masayuki, Momose, Toshimitsu, Ito, Kengo, Okamura, Terue, Oda, Keiichi, Kuge, Yuji, Sakurai, Minoru, Tateishi, Ukihide, Fujibayashi, Yasuhisa, Magata, Yasuhiro, Yoshida, Takeshi, Waki, Atsuo, Kato, Katsuhiko, Hashimoto, Teisuke, Uchiyama, Mayuki, Kinuya, Seigo, Higashi, Tatsuya, Magata, Yasuhiro, Machitori, Akihiro, Maruno, Hirotaka, Minamimoto, Ryogo, and Yoshinaga, Keiichiro

Published
2021
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32. MAXI observations of GRBs

Author

Serino, Motoko, Sakamoto, Takanori, Kawai, Nobuyuki, Yoshida, Atsumasa, Ohno, Masanori, Ogawa, Yuji, Nishimura, Yasunori, Fukushima, Kosuke, Higa, Masaya, Ishikawa, Kazuto, Ishikawa, Masaki, Kawamuro, Taiki, Kimura, Masashi, Matsuoka, Masaru, Mihara, Tatehiro, Morii, Mikio, Nakagawa, Yujin E., Nakahira, Satoshi, Nakajima, Motoki, Nakano, Yuki, Negoro, Hitoshi, Onodera, Takuya, Sasaki, Masayuki, Shidatsu, Megumi, Sugimoto, Juri, Sugizaki, Mutsumi, Suwa, Fumitoshi, Suzuki, Kazuhiko, Tachibana, Yutaro, Takagi, Toshihiro, Toizumi, Takahiro, Tomida, Hiroshi, Tsuboi, Yohko, Tsunemi, Hiroshi, Ueda, Yoshihiro, Ueno, Shiro, Usui, Ryuichi, Yamada, Hisaki, Yamamoto, Takayuki, Yamaoka, Kazutaka, Yamauchi, Makoto, Yoshidome, Koshiro, and Yoshii, Taketoshi

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

Monitor of all-sky image (MAXI) Gas Slit Camera (GSC) detects gamma-ray bursts (GRBs) including the bursts with soft spectra, such as X-ray flashes (XRFs). MAXI/GSC is sensitive to the energy range from 2 to 30 keV. This energy range is lower than other currently operating instruments which is capable of detecting GRBs. Since the beginning of the MAXI operation on August 15, 2009, GSC observed 35 GRBs up to the middle of 2013. One third of them are also observed by other satellites. The rest of them show a trend to have soft spectra and low fluxes. Because of the contribution of those XRFs, the MAXI GRB rate is about three times higher than those expected from the BATSE log N - log P distribution. When we compare it to the observational results of the Wide-field X-ray Monitor on the High Energy Transient Explorer 2, which covers the the same energy range to that of MAXI/GSC, we find a possibility that many of MAXI bursts are XRFs with Epeak lower than 20 keV. We discuss the source of soft GRBs observed only by MAXI. The MAXI log N - log S distribution suggests that the MAXI XRFs distribute in closer distance than hard GRBs. Since the distributions of the hardness of galactic stellar flares and X-ray bursts overlap with those of MAXI GRBs, we discuss a possibility of a confusion of those galactic transients with the MAXI GRB samples., Comment: 12 figures

Published
2014
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33. AIF3 splicing switch triggers neurodegeneration

Author

Liu, Shuiqiao, Zhou, Mi, Ruan, Zhi, Wang, Yanan, Chang, Calvin, Sasaki, Masayuki, Rajaram, Veena, Lemoff, Andrew, Nambiar, Kalyani, Wang, Jennifer E., Hatanpaa, Kimmo J., Luo, Weibo, Dawson, Ted M., Dawson, Valina L., and Wang, Yingfei

Published
2021
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40. The 37-month MAXI/GSC source catalog in the high Galactic-latitude sky

Author

Hiroi, Kazuo, Ueda, Yoshihiro, Hayashida, Masaaki, Shidatsu, Megumi, Sato, Ryosuke, Kawamuro, Taiki, Sugizaki, Mutsumi, Nakahira, Satoshi, Serino, Motoko, Kawai, Nobuyuki, Matsuoka, Masaru, Mihara, Tatehiro, Morii, Mikio, Nakajima, Motoki, Negoro, Hitoshi, Sakamoto, Takanori, Tomida, Hiroshi, Tsuboi, Yohko, Tsunemi, Hiroshi, Ueno, Shiro, Yamaoka, Kazutaka, Yoshida, Atsumasa, Asada, Masato, Eguchi, Satoshi, Hanayama, Takanori, Higa, Masaya, Ishikawa, Kazuto, Ishikawa, Masaki, Isobe, Naoki, Kohama, Mitsuhiro, Kimura, Masashi, Morihana, Kumiko, Nakagawa, Yujin E., Nakano, Yuki, Nishimura, Yasunori, Ogawa, Yuji, Sasaki, Masayuki, Sugimoto, Juri, Takagi, Toshihiro, Usui, Ryuichi, Yamamoto, Takayuki, Yamauchi, Makoto, and Yoshidome, Koshiro

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

We present the catalog of high Galactic-latitude ($|b|>10^{\circ}$) X-ray sources detected in the first 37-month data of Monitor of All-sky X-ray Image (MAXI) / Gas Slit Camera (GSC). To achieve the best sensitivity, we develop a background model of the GSC that well reproduces the data based on the detailed on-board calibration. Source detection is performed through image fit with the Poisson likelihood algorithm. The catalog contains 500 objects detected in the 4--10 keV band with significance of $s_{\rm D, 4-10 keV} \geq 7$. The limiting sensitivity is $\approx 7.5\times10^{-12}$ ergs cm$^{-2}$ s$^{-1}$ ($\approx 0.6$ mCrab) in the 4--10 keV band for 50% of the survey area, which is the highest ever achieved as an all-sky survey mission covering this energy band. We summarize the statistical properties of the catalog and results from cross matching with the Swift/BAT 70-month catalog, the meta-catalog of X-ray detected clusters of galaxies, and the MAXI/GSC 7-month catalog. Our catalog lists the source name (2MAXI), position and its error, detection significances and fluxes in the 4--10 keV and 3--4 keV bands, their hardness ratio, and basic information of the likely counterpart available for 296 sources., Comment: 21 pages, 15 figures, 3 tables, accepted for publication in ApJS

Published
2013
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41. Is the Cygnus Superbubble a Hypernova Remnant?

Author

Kimura, Masashi, Tsunemi, Hiroshi, Tomida, Hiroshi, Sugizaki, Mutsumi, Ueno, Shiro, Hanayama, Takanori, Yoshidome, Koshiro, and Sasaki, Masayuki

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

We present here the observation of the Cygnus Superbubble (CSB) using the Solid-state slit camera (SSC) aboard the Monitor of All-sky X-ray Image. The CSB is a large diffuse structure in the Cygnus region with enhanced soft X-ray emission. By utilizing the CCD spectral resolution of the SSC, we detect Fe, Ne, Mg emission lines from the CSB for the first time. The best fit model implies thin hot plasma of kT ~ 0.3 keV with depleted abundance of 0.26 +/- 0.1 solar. Joint spectrum fitting of the ROSAT PSPC data and MAXI/SSC data enables us to measure precise values of NH and temperature inside the CSB. The results show that all of the regions in the CSB have similar NH and temperature, indicating that the CSB is single unity. The energy budgets calculation suggests that 2-3 Myrs of stellar wind from the Cyg OB2 is enough to power up the CSB, whereas due to its off center position, the origin of the CSB is most likely a Hypernova., Comment: 15 pages 8 figures

Published
2012
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45. TCT-649 Impact of a Novel Hybrid Nanocoated Nitinol Drug-Eluting Stent on Below-the-Knee Atherosclerotic Disease: 2023 Update

Author

Hasebe, Terumitsu, primary, Maegawa, Shunto, additional, Bito, Kenta, additional, Kamei, Shunsuke, additional, Usami, Yoko, additional, Ogawa, Yukihisa, additional, Okamoto, Yutaka, additional, Ishikawa, Taku, additional, Sasaki, Masayuki, additional, Hosaka, Makoto, additional, Matsuoka, Emi, additional, Matsumoto, Tomohiro, additional, Yamagami, Takuji, additional, Baba, Yasutaka, additional, and Edelman, Elazer, additional

Published
2023
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