Search

In Japan, many pregnant women and mothers suffer from anxiety, depression, and other postnatal issues that can be exacerbated by their birth experiences. While benefiting from advanced medical care, these women's mental and psychological health may be disregarded in their maternity care. Midwives have the potential to play a significant role in improving women's birth experiences. Hence, this study aimed to explore the meaning of the woman–midwife relationship, with a specific focus on sensing peace of mind and trust to improve women's birth experiences. Using a hermeneutic phenomenological approach, 14 Japanese women were interviewed. Sensing peace of mind and trust was one of the significant meanings of the woman–midwife relationship and is articulated across five themes: (1) attuning to the world, (2) different kinds of safety and trust, (3) relying on and entrusting midwives, (4) making a mother, and (5) an emotional bridge. The positive relationship with midwives enhanced the women's mental well-being through allowing the women to attune to the peaceful mind which directed their future perspectives and sustained them in motherhood. They became confident mothers by trusting their midwives. The maternity care system in Japan needs to shift to more relationship-based care to ensure continuity of midwifery care that will improve women's birth experiences and their long-term well-being. [ABSTRACT FROM AUTHOR]

African swine fever (ASF) is a highly contagious and severe hemorrhagic transboundary swine viral disease with up to a 100% mortality rate, which leads to a tremendous socio-economic loss worldwide. The lack of safe and efficacious ASF vaccines is the greatest challenge in the prevention and control of ASF. In this study, we generated a safe and effective live-attenuated virus (LAV) vaccine candidate VNUA-ASFV-LAVL3 by serially passaging a virulent genotype II strain (VNUA-ASFV-L2) in an immortalized porcine alveolar macrophage cell line (3D4/21, 50 passages). VNUA-ASFV-LAVL3 lost its hemadsorption ability but maintained comparable growth kinetics in 3D4/21 cells to that of the parental strain. Notably, it exhibited significant attenuation of virulence in pigs across different doses (103, 104, and 105 TCID50). All vaccinated pigs remained healthy with no clinical signs of African swine fever virus (ASFV) infection throughout the 28-day observation period of immunization. VNUA-ASFV-LAVL3 was efficiently cleared from the blood at 14–17 days post-infection, even at the highest dose (105 TCID50). Importantly, the attenuation observed in vivo did not compromise the ability of VNUA-ASFV-LAVL3 to induce protective immunity. Vaccination with VNUA-ASFV-LAVL3 elicited robust humoral and cellular immune responses in pigs, achieving 100% protection against a lethal wild-type ASFV (genotype II) challenge at all tested doses (103, 104, and 105 TCID50). Furthermore, a single vaccination (104 TCID50) provided protection for up to 2 months. These findings suggest that VNUA-ASFV-LAVL3 can be utilized as a promising safe and efficacious LAV candidate against the contemporary pandemic genotype II ASFV. [ABSTRACT FROM AUTHOR]

To address the issue of inconsistencies between the 3D structural models built on Building Information Modeling (BIM) platforms and the original structural designs, thereby ensuring structural safety and reliability, this paper proposes an integrated design approach for prefabricated steel frame structures based on BIM technology with a primary focus on structural safety. The application of the integrated design methodology for prefabricated steel frame structures, leveraging BIM technology, is concretely demonstrated through case studies. These illustrations focus on pivotal aspects: assessing the overall safety performance of the structure, conducting meticulous analyses of beam-to-column connection nodes, and harnessing the outcomes of these evaluations to inform and direct the optimization of the structural design. The research findings presented herein offer insights and methodologies for applying BIM in safety assessments of prefabricated steel frame structures, thereby further refining the comprehensive framework of BIM engagement throughout the entire life cycle of prefabricated steel frame construction projects. [ABSTRACT FROM AUTHOR]

Background: Botulinum neurotoxin (BoNT) and filler injections into the highly vascularized glabellar region for aesthetical purposes are extremely common. Injections into the glabellar region without precise anatomical knowledge of its vascular and muscular topography may pose the risk of severe complications. Objectives: We aimed to improve the safety and efficacy of the glabellar injections by mapping the regional muscles and vasculature in relation to the medial canthus and the defined reference lines. Methods: Meticulous dissection was performed to reveal glabellar region muscles and arteries under surgical microscope, in 16 hemifaces of whom arteries are injected with red-dyed latex. Location of the angular artery (AA) along with its branches was noted in relation to glabellar muscles. Results: The AA was always located superficial to the levator labii superioris alaeque nasi muscle (LLSAN) and then coursed toward the medial canthus to anastomose with the supratrochlear artery deep to the origin of the depressor supercilii (DS). The AA gave subcutaneously located central and paracentral branches coursing close to the mid-face line in 14 out of 16 hemifaces. Variable muscular connections were also present between the LLSAN, the DS and the procerus (P) muscles. No arteries were detected at the base of the medial eyebrow to which the DS, the P, and the frontalis (F) inserted. Conclusions: This study provides a detailed map of muscular and vascular anatomy of the glabellar region to facilitate safe and efficient filler and BoNT injections without complications. No Level Assigned: This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266. [ABSTRACT FROM AUTHOR]

In 2020, firearm‐related injuries became the leading cause of death in American children. Ensuring the safe storage of household firearms is one way to reduce those deaths. Since the 1990s, states have sought to accomplish that goal through child access prevention (CAP) laws, which sanction gun owners for unsafe firearm storage. However, recent survey data suggests that these laws are not effective, as they suffer from low compliance. To compensate for these shortcomings, legislators should repeal CAP laws and devise legislation requiring gun owners residing with children to retrofit their household firearms with smart gun technology. Key points for the family law community: 4368 American children were killed by firearm‐related injuries in 2020.Only 19.9% of the firearms used in youth suicides and unintentional injuries were properly stored.4.6 million American children live in homes where at least one firearm is loaded and not locked away.The firearm industry is exempt from federal agency oversight and is largely shielded from tort liability.Child access prevention laws have had a negligible effect on firearm storage practices. [ABSTRACT FROM AUTHOR]

The industrial designer plays an essential role in influencing aspects of safety, health, and risk management in workplace, in addition to achieving the safe design of products and structures that he develops before building and implementing them in workplaces. Designers must participate from the beginning of the project to obtain the desired benefit & influence the design increases and the cost of integrating health and safety solutions decreases with the development of the design project life cycle. The theoretical framework of the research included the study of workplaces and occupational safety and health to determine the types of those environments and classification of risks in them, the concept of safe design and how to achieve safety in design, and to clarify the role of occupational safety and health in design. The research analytical framework, resulted in a strategy for safe design, and the risk management process, tools, and methods used in that process, was integrated within that strategy to assist the industrial designer in analyzing and identifying those risks, and providing innovative design solutions to reduce the risks that the worker faces in workplace & ensures that the achievement of occupational safety and health standards while executing the responsibilities entrusted to him. This strategy has been applied to one of the risks of the workplace to which the worker is exposed, which is the risk of falling from heights or slipping through the development of innovative design solutions for mobile ladders used in performing tasks in the work environments.

The development of medical technology devices leads to the introduction and use of agile methods, which enable the delivery of increasingly complex software with the fastest possible innovations. Delivery of the highest quality software must be considered during development, as medical products are important elements in saving human lives. Their development begins with determining a set of product requirements that exactly correspond to it. The development of specified medical products is finally delivered to the customer, who participates in the development. In this article, we present the use and combination of agile methods in software development, which correct and facilitate timely and continuous delivery of products. They also know how to smooth out a quick reaction to the customer's changing needs and mainly focus on team management and communication. Specific agile methods make it possible to implement development through gradual improvements by integrating customer requirements towards the product. This article identifies three interconnected approaches to integrating agile methods and principles: SCRUM, SAFe, and Kanban combined with the V-model. The methods are gradually analysed based on the literature review, and the article presents a practical application in Siemens Healthcare Slovakia. [ABSTRACT FROM AUTHOR]

Background: Pesticides play a crucial role in enhancing agricultural productivity by controlling pests. However, inadequate pesticide handling practices have a considerable adverse impact on human health. Nevertheless, there is limited knowledge regarding the extent of safe pesticide handling practices, particularly in low-income settings like Ethiopia. Hence, this study seeks to evaluate the implementation of safe pesticide handling practices and identify the factors associated with the status of the handling practices in low-income settings in Ethiopia. Methods: A cross-sectional study was undertaken, involving 468 farmers randomly selected for participation. Data collection was carried out through structured questionnaires and face-to-face interviews. The analysis aimed to assess the proportion of safe pesticide handling practices (SPHP) and investigate the factors associated with SPHP was done using binary logistic regression. Explanatory variables with a P -value <0.25 were included in the final analysis. The factors were determined based on adjusted odds ratios and 95% confidence intervals, P -value <.05. Model fit was evaluated using the Hosmer and Lemeshow tests. Results: From the findings of our study, only 45.7% of farmers practiced SPHP, with factors such as education, experience, pesticide usage, and attitude toward safe practices influencing their practices. Farmers with education status primary and above were two times more likely to practice good handling of pesticides than those who didn't attend formal education. Farmers with a maximum of 5 years of experience in vegetable farming were 2.4 times more likely to exhibit good handling practices compared to their counterparts. Furthermore, farmers with favorable attitudes toward pesticide handling were 4.2 times more likely to engage in good pesticide handling practices than those with unfavorable attitudes. Therefore, the agricultural sectors, health sectors, and farmer associations should focus on these factors in order to mitigate the health risks associated with poor pesticide handling. [ABSTRACT FROM AUTHOR]

This paper studies the problem of coordination and supervision of virtual teams and their capabilities. The goal is to develop a model suitable for managing virtual student teams specialized in the development of smart environments. The developed model is based on SAFe and DevOps, which when combined provide us with a framework for the evaluation of team capabilities in an academic environment. Additionally, DevOps principles can be more efficiently leveraged through an agile methodology to provide students with a better understanding of continuous value delivery. Through the application of the proposed model, virtual student teams gained practical experience in self-organization and virtual team management while being efficiently monitored and guided through the project lifecycle. Virtual student teams were likewise encouraged to be more agile, as this change in mindset is imperative in business, and as such must also be adopted in academic environments. By incorporating best practices of the corporate environments into the existing curriculum, we have proven that by adopting the proposed model these changes can be feasibly incorporated to the satisfaction of both the students and their future employers. [ABSTRACT FROM AUTHOR]

School plays a crucial role in shaping adolescent identity, but despite today's perception of being more accepting, LGBT students still face challenges. This study explored student attitudes toward homosexuality and its correlations with age, gender, religious involvement, exposure to LGBT communities, and preferences for LGBT-themed media. Data was collected from 312 students aged 12-16 in a Claveria West District school during the 2022-2023 academic year using a Likert scale survey. The analysis involved frequency counts, percentages, weighted means, and Pearson correlations in IBM SPSS Statistics. Results showed that 55.40% of respondents were male and 44.60% were female, with an average age of 14. Overall, attitudes towards homosexuality in school were generally liberal and accepting across various contexts. Participants were open to working with homosexual peers, joining organizations with LGBT members, and having homosexual teachers. The study found significant associations between attitudes and age, gender, church attendance, personal LGBT experiences, and media preferences, while religion and exposure to LGBT communities showed no significant correlation. The study recommends mechanisms for creating safe and inclusive schools for LGBT students. [ABSTRACT FROM AUTHOR]

In this paper we propose a revised Decision Making Trial and Evaluation Laboratory (DEMATEL), called stochastic DEMATEL, to extract structural model of a complex problematique and to represent the priority of each factor taking into account the uncertainty of structure. In the stochastic DEMATEL, the uncertainty of structure is expressed as a stochastic model. From numerical experiments and experimental analyses, the following results are obtained: when the structure is uncertain, stochastic DEMATEL could extract the features of structure by the degree of dispatching influences and the degree of central role; stochastic composite importance could express the uncertainty of priority and decide the priority taking into account the attitude of the decision maker; pessimistic, neutral or optimistic. [ABSTRACT FROM AUTHOR]

ABSTRACTBackground In the absence of a specific treatment for COVID-19, preventive measures have been implemented to control this pandemic and vaccination is one of them. However, it is crucial to verify the safety and efficiency of every vaccine. The aim was to determinate the predictive factors of side effects and reinfection after COVID-19 vaccine. Methods A cross-sectional study was conducted in February 2022 among Tunisians infected with COVID-19 between March 2020 and February 2022, using an online self-administered questionnaire. We conducted univariate and multivariate analyses using binary stepwise logistic regression. Results A total of 1541 was selected from 1911 individuals. Comorbidities affected a quarter of the population (22.3%). Before the initial infection, 39.3% had received full vaccination, and 8.7% had received partial vaccination. By February 2022, the majority (82.9%) had received at least two vaccine doses. The reinfection rate was 30.6%. All vaccines prior to the first infection was identified as a protective factor against reinfection. Inactivated virus vaccinations were less likely to induce adverse effects. Conclusion ach vaccine has its own set of advantages and disadvantages: mRNA-based vaccines had a higher incidence of side effects but all vaccines provided better protection against reinfection.

This study applied a case study approach to explore the participation experiences of children with physical disabilities in a community school in Mumbai to understand how schools might improve their students' meaningful participation and social interaction. This study identified three categories of focus: (1) physically accessible and safe school spaces, (2) informal spaces for community and social engagement and socialization, and (3) future directions for school design. We offer specific recommendations for school designers to value children's voices and incorporate their disability-related needs in the design of school spaces. We outline key design considerations to create safe, accessible, and engaging school spaces. [ABSTRACT FROM AUTHOR]

Copyright of Projekt-Management Aktuell is the property of Narr Francke Attempto Verlag GmbH & Co.KG and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The effects of a holistic attachment-based primary prevention program (SAFE), which is aimed at fathers and mothers during the transition to parenthood, were assessed over the 7-year post-intervention follow-up of a randomized control trial. A non-clinical German sample was included in the trial (fathers: n = 58, mothers: n = 71; children: n = 72). The children's mean age was 7.30 years (SD = 0.41) and their attachment representations were assessed using a doll play procedure. Among the group of insecure mothers (n = 58), significantly more children (50%) in the SAFE group displayed a secure attachment representation compared to the control group (25%). No children of mothers with unresolved trauma displayed a disorganized attachment representation. In the parent domain, the increase in couple discord over time perceived by the SAFE mothers was significantly lower than that for the mothers in the control group. Furthermore, mothers in the SAFE group reported significantly higher partnership quality than the control mothers. The perceived benefits of the programs were significantly higher, in multiple domains, among SAFE fathers and mothers compared to control parents. The effect sizes were medium to large. Even after 7 years, program participation continues to have a positive impact on the children, and their fathers and mothers. The most important implication of this study for clinical practice is the need to support mothers with insecure or unresolved trauma in order to promote healthy child development. In addition, we think that it is important to support both parents during the transition to parenthood. TRN: DRKS00017050 (retrospectively registered, March, 28th 2019) Highlights: We assessed the effects of an attachment-based intervention 7 years post-intervention in a randomized control trial. The intervention is aimed at fathers and mothers. The program addressed the quality of the parent's relationships and the parent-child relationships. Participation improved maternal partnership quality and attenuated the increase in couple discord experienced by mothers. The risk of the intergenerational transmission of insecure attachment was attenuated in mothers. [ABSTRACT FROM AUTHOR]

Copyright of Food Science & Technology & Economy is the property of Grain Science & Technology & Economy Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Scaled agile development approaches are now used widely in modern software engineering, allowing businesses to improve teamwork, productivity, and product quality. The incorporation of artificial intelligence (AI) into scaled agile development methods (SADMs) has emerged as a potential strategy in response to the ongoing demand for simplified procedures and the increasing complexity of software projects. This paper explores the intersection of AI-driven assistants within the context of the scaled agile framework (SAFe) for large-scale software development, as it stands out as the most widely adopted framework. Our paper pursues three principal objectives: (1) an evaluation of the challenges and impediments encountered by organizations during the implementation of SADMs, (2) an assessment of the potential advantages stemming from the incorporation of AI in large-scale contexts, and (3) the compilation of aspects of SADMs that AI-driven assistants enhance. Through a comprehensive systematic literature review, we identified and described 18 distinct challenges that organizations confront. In the course of our research, we pinpointed seven benefits and five challenges associated with the implementation of AI in SADMs. These findings were systematically categorized based on their occurrence either within the development phase or the phases encompassing planning and control. Furthermore, we compiled a list of 15 different AI-driven assistants and tools, subjecting them to a more detailed examination, and employing them to address the challenges we uncovered during our research. One of the key takeaways from this paper is the exceptional versatility and effectiveness of AI-driven assistants, demonstrating their capability to tackle a broader spectrum of problems. In conclusion, this paper not only sheds light on the transformative potential of AI, but also provides invaluable insights for organizations aiming to enhance their agility and management capabilities. [ABSTRACT FROM AUTHOR]

To comprehensively analyze the composition and contribution of volatile components in Rosa sterilis, the headspace solid phase microextraction (HS-SPME) and liquid liquid extraction with solvent assisted flavor evaporation (LLE-SAFE) was used, along with gas chromatography-mass spectrometry (GC-MS) to analyze the volatile components. The odor active value (OAV) was used to evaluate the contribution of volatile components to the overall aroma of R. sterilis juice. The results showed that a total of 115 volatile components were identified using both methods, with 59 identified using HS-SPME and 75 identified using LLE-SAFE. These components included 25 esters, 27 alcohols, 11 aldehydes, 14 ketones, 18 acids, 14 terpenes, and 6 other compounds. Analysis of the odor active value (OAV) showed that 30 volatile components, including isoamyl alcohol, 2-hexenal, ethyl hexanoate, ethyl acetate, butyl acetate, hexanal, and hexanoic acid, contributed strongly to the aroma of R. sterilis. This study provides theoretical support for revealing the aroma profile and chemical essence of R. sterilis.

African swine fever (ASF) is a highly contagious and severe hemorrhagic transboundary swine viral disease with up to a 100% mortality rate, which leads to a tremendous socio-economic loss worldwide. The lack of safe and efficacious ASF vaccines is the greatest challenge in the prevention and control of ASF. In this study, we generated a safe and effective live-attenuated virus (LAV) vaccine candidate VNUA-ASFV-LAVL3 by serially passaging a virulent genotype II strain (VNUA-ASFV-L2) in an immortalized porcine alveolar macrophage cell line (3D4/21, 50 passages). VNUA-ASFV-LAVL3 lost its hemadsorption ability but maintained comparable growth kinetics in 3D4/21 cells to that of the parental strain. Notably, it exhibited significant attenuation of virulence in pigs across different doses (103, 104, and 105 TCID50). All vaccinated pigs remained healthy with no clinical signs of African swine fever virus (ASFV) infection throughout the 28-day observation period of immunization. VNUA-ASFV-LAVL3 was efficiently cleared from the blood at 14–17 days post-infection, even at the highest dose (105 TCID50). Importantly, the attenuation observed in vivo did not compromise the ability of VNUA-ASFV-LAVL3 to induce protective immunity. Vaccination with VNUA-ASFV-LAVL3 elicited robust humoral and cellular immune responses in pigs, achieving 100% protection against a lethal wild-type ASFV (genotype II) challenge at all tested doses (103, 104, and 105 TCID50). Furthermore, a single vaccination (104 TCID50) provided protection for up to 2 months. These findings suggest that VNUA-ASFV-LAVL3 can be utilized as a promising safe and efficacious LAV candidate against the contemporary pandemic genotype II ASFV.

To address the issue of inconsistencies between the 3D structural models built on Building Information Modeling (BIM) platforms and the original structural designs, thereby ensuring structural safety and reliability, this paper proposes an integrated design approach for prefabricated steel frame structures based on BIM technology with a primary focus on structural safety. The application of the integrated design methodology for prefabricated steel frame structures, leveraging BIM technology, is concretely demonstrated through case studies. These illustrations focus on pivotal aspects: assessing the overall safety performance of the structure, conducting meticulous analyses of beam-to-column connection nodes, and harnessing the outcomes of these evaluations to inform and direct the optimization of the structural design. The research findings presented herein offer insights and methodologies for applying BIM in safety assessments of prefabricated steel frame structures, thereby further refining the comprehensive framework of BIM engagement throughout the entire life cycle of prefabricated steel frame construction projects.

Due to the increasing importance of the insurance market in the Brazilian economy, reflected in its significant contribution to the national GDP and its influence on various sectors, it is essential to understand the dynamics of this sector to ensure the economic and financial balance of insurance companies through solid performance. In this context, this study aimed to identify the factors that significantly impact the profitability of Brazilian insurers. Using a sample of 63 Brazilian insurers over an eight-year period from 2014 to 2021, panel data modeling was employed as the analytical technique. The study sought to relate and identify potential influencers on the profitability, measured by Return on Assets (ROA), of the insurers in the sample. The selected variables to test for influences on profitability were: capital volume, leverage, loss ratio, extended combined ratio, and sector of operation. Based on existing literature, five hypotheses were formulated to test the significance of the adopted variables. The results revealed that only leverage, extended combined ratio, and sector of operation showed statistical significance in explaining the dependent variable ROA, thereby confirming three of the formulated hypotheses. [ABSTRACT FROM AUTHOR]

Greater impact on patient outcomes may have occurred if, following the course, providers were equipped with guidelines for evaluating patients earlier through pre-operative assessments or if antenatal care protocols were a greater focus in the curriculum. Practice change (behaviour) must improve the quality of patient care, and patient care must result in better outcomes for patients (results). Keywords: continuous medical education; continuous professional development; knowledge translation; obstetric anaesthesia; SAFE EN continuous medical education continuous professional development knowledge translation obstetric anaesthesia SAFE 1323 1326 4 10/11/23 20231101 NES 231101 Disparities in health outcomes continue to shock. Residency training for physicians is known to improve patient outcomes, but patient care requires a team approach, necessitating all members receive adequate training [[21]]. [Extracted from the article]

Summary: Anaesthesia has been shown to contribute disproportionately to maternal mortality in low‐resource settings. This figure exceeds 500 per 100,000 live births in Tanzania, where anaesthesia is mainly provided by non‐physician anaesthetists, many of whom are working as independent practitioners in rural areas without any support or opportunity for continuous medical education. The three‐day Safer Anaesthesia from Education (SAFE) course was developed to address this gap by providing in‐service training in obstetric anaesthesia to improve patient safety. Two obstetric SAFE courses with refresher training were delivered to 75 non‐physician anaesthetists in the Mbeya region of Tanzania between August 2019 and July 2020. To evaluate translation of knowledge into practice, we conducted direct observation of the SAFE obstetric participants at their workplace in five facilities using a binary checklist of expected behaviours, to assess the peri‐operative management of patients undergoing caesarean deliveries. The observations were conducted over a 2‐week period at pre, immediately post, 6‐month and 12‐month post‐SAFE obstetric training. A total of 320 cases completed by 35 participants were observed. Significant improvements in behaviours, sustained at 12 months after training included: pre‐operative assessment of patients (32% (pre‐training) to 88% (12 months after training), p < 0.001); checking for functioning suction (73% to 85%, p = 0.003); using aseptic spinal technique (67% to 100%, p < 0.001); timely administration of prophylactic antibiotics (66% to 95%, p < 0.001); and checking spinal block adequacy (32% to 71%, p < 0.001). Our study has demonstrated positive sustained changes in the clinical practice amongst non‐physician anaesthetists as a result of SAFE obstetric training. The findings can be used to guide development of a checklist specific for anaesthesia for caesarean section to improve the quality of care for patients in low‐resource settings. [ABSTRACT FROM AUTHOR]

Poverty remains an inherent reality in the lives of Indonesian people, largely due to the prolonged economic downturn faced by the nation. This issue is prevalent in developing countries, including Indonesia, affecting a significant portion of its population. To address this challenge, Allah Almighty has established zakat, infak, and alms, encouraging financially capable Muslims to show compassion for the poor and fostering a harmonious relationship between the two. The purpose of this study is to explore the concept of safe zakat management, ensuring compliance with prevailing laws and regulations in Indonesia. The article adopts the normative juridical method with a normative sociological approach, relying on secondary data sources and employing analytical descriptive methods for analysis. To tackle poverty effectively, cooperation with both government and private institutions, known for their proficient financial management, is crucial. This collaboration serves as an effort to overcome these social problems. In managing zakat, there are specific rules that govern both positive law and Islamic law. It is essential for this management to align with applicable regulations and the provisions of Islamic law. Through such efforts, the public can gain a comprehensive understanding of how to manage zakat safely and in accordance with the relevant regulations, ensuring it is halal (permissible) in line with Islamic principles. [ABSTRACT FROM AUTHOR]

To ensure the safety and energy efficiency of autonomous sampling operations for a deep-sea landing vehicle (DSLV), the Safety Energy-Dynamic Window Approach (SE-DWA) algorithm was proposed. The safety assessment sub-function formed from the warning obstacle zone and safety factor addresses the safety issue arising from the excessive range measurement error of forward-looking sonar. The trajectory comparison evaluation sub-function with the effect of reducing energy consumption achieves a reduction in path length by causing the predicted trajectory to deviate from the historical trajectory when encountering "U"-shaped obstacles. The pseudo-power evaluation sub-function with further energy consumption reduction ensures optimal linear and angular velocities by minimizing variables when encountering unknown obstacles. The simulation results demonstrate that compared with the Minimum Energy Consumption-DWA algorithm, the SE-DWA algorithm improves the minimum distance to an actual obstacle zone by 68% while reducing energy consumption by 11%. Both the SE-DWA algorithm and the Maximum Safety-DWA (MS-DWA) algorithm ensure operational safety with minimal distance to the actual obstacle zone, yet the SE-DWA algorithm achieves a 24% decrease in energy consumption. In conclusion, the path planned by the SE-DWA algorithm ensures not only safety but also energy consumption reduction during autonomous sampling operations by a DSLV in the deep sea. [ABSTRACT FROM AUTHOR]

Aroma compounds in the roasted breasts, thighs and skins of chicken were isolated by solvent-assisted flavor evaporation (SAFE), quantitated by gas chromatography–olfactometry-mass (GC-O-MS), analyzed by aroma extract dilution analysis (AEDA), and determined by recombination-omission tests and sensory evaluation. Forty-seven aroma compounds in total, including aldehydes, ketones, furans, pyrazines, and furanones, were selected by AEDA. Twenty-five compounds were selected as pivotal odorants (Odor Activity Value, OAV ≥ 1). Twenty aroma compounds significantly were identified by recombination and omission experiments. Anethole (fennel odor) was the highest OAV (＞ 1843). Hexanal (grassy) and (E, E)-2,4-decadienal (meaty) were the most abundant aldehydes identified in roasted chicken. 1-octen-3-ol (mushroom), methanethiol (cabbage) and dimethyl trisulfide (areca, sulfur) were considered the key compounds of the breast and thighs of roasted chicken. Notably, furanone and pyrazines, 4-hydroxy-5-methyl-3(2H)-furanone (caramel, sweet and burning odor), 3-ethyl-2,5-dimethylpyrazine (nutty, toasty) and 2,3-dimethyl-5-ethylpyrazine (nutty, toasty) had the most significant effect on roasted chicken odor, especially in the skin.

Abstract Approximately 2 billion people globally have limited access to essential medicines, particularly those living in low‐ and middle‐income countries (LMICs). In addition, there is a higher prevalence of substandard and counterfeit medicines in LMICs, which may cause antimicrobial resistance and therapeutic failure. Good manufacturing practice (GMP) is key to ensuring access to high‐quality, safe and effective medicines, including active pharmaceutical ingredients and excipients used for manufacturing finished dosage forms. Compliance with GMP standards saves resources for both manufacturers (e.g. avoiding expensive product recalls) and governments (e.g. minimising compliance inspections). Concerted collaborations among different countries to harmonise GMP standards and procedures have occurred, and the World Health Organisation (WHO) GMP is commonly used in LMICs. However, barriers to GMP compliance remain apparent, particularly in LMICs. Pharmaceutical manufacturers in LMICs face several barriers such as inadequate resources and infrastructure, inefficient or weak regulation, a shortage of skilled people and limited training opportunities for manufacturing personnel. Although national regulatory authorities (NRAs) have been established in LMICs, most NRAs are not fully independent and are placed within the health department. NRAs in LMICs are not able to fully utilise international and regional reliance mechanisms and collaborations. Therefore, both NRAs and pharmaceutical manufacturers must be adequately supported through resources, infrastructure and capacity‐building opportunities. NRAs must be suitably empowered with assured functional independence. A comprehensive guideline for managing conflicts of interest among pharmaceutical manufacturers, procurement agencies and NRAs is needed. NRAs must liaise with other NRAs, participate in joint GMP inspections and leverage the expertise of regional or international collaborations. Pharmaceutical manufacturers in LMICs can leverage WHO GMP standards to improve GMP compliance and expand their market. However, as these solutions may have cost implications, prioritising key gaps for GMP compliance and optimisation of available resources are essential.

Highlights High Coulombic efficiency of over 99% for dendrite-free K||Cu cell after 820 cycles. Year-scale-cycling performance of organic PTCDI cathode over 2,100 cycles. Flexible device demonstration such as fibre cell still could operate when cut into three fibre cells.

At present, migration has the highest growth rates, a trend that is maintained, putting pressure on all states for its good governance. In this context, the aim of the paper is a comparative analysis, at global, regional and European level, of the implementation of measures in the areas of migration policies, according to target objective 10.7.2 of the 2030 Agenda, to ensure a Safe, Orderly, Regular and Responsible Migration and mobility of people. In order to operationalize the follow-up of the situation on the fulfilment of this objective, based on the migration governance framework, MiGOF, six key political areas were established, each with five defining subcategories in its structure, followed in almost all the countries of the world. The overall indicator 10.7.2 obtained by aggregating the scores of the 30 resulting subcategories and the six domains constitutes a comprehensive and complex instrument at the disposal of the states, based on which these can identify concrete measures and actions, necessary to be undertaken to fulfil the proposed general objective. The data on indicator 10.7.2 are available as a result of two surveys, carried out in 2018-2019 and 2020-2021, through the international migration module of the United Nations, for 138 countries, representing 70% of the 197 states included in the last inquiry. The application of these policies is very uneven between countries, this is also the case in Europe. The evaluation of the surveyed data, as well as the analysis of migration policy networks, allows the identification of the most important measures applied in European countries, as well as those with the lowest performances, which require consistent revisions by governments in order to achieve their integration goals of migrants.

AbstractThe school canteen must provide nutritious, safe, and halal food. During the COVID-19 pandemic, it was not easy to manage the canteen operations. This study aims to map the barrier, driving factors, and priorities strategy to prepare for reopening the senior high school’s canteen with safe and halal standards in the new normal era. This study was analytically observational with a cross-sectional approach in nature. SWOT and Fuzzy-ANP (F-ANP) methods identified and determined the priority strategies. The SWOT analysis results show that internal factors are moderate, but external factors strongly influence the school canteen’s position, hence growth and development strategies are required. Based on weighted priority by F-ANP six strategies are recommended. The six strategies to reopen safe and halal of Senior High School canteen are as follows: establish school canteen management commitment with food handlers and other stakeholders with distinct communication; develop safe and halal school canteens, the authority should consider affordable menu prices; serving a variety of safe and halal menus according to the purchasing power, mainly students; conduct education or training according to the needs of school academia and canteen management for food safety and halal; develop new menus or re-formulate existing menus considering school academia and supporting food safety, halal, and nutrition; and finally, conduct training on processing and serving safe and halal menus for school canteen managers and food handlers. These alternative strategies are expected to better prepare for reopening the school canteen with safe and halal standards in the new normal era.

Restrictions imposed by the COVID‐19 pandemic have forced many to seek alternative means of training and learning, which ended up with increasing investment in the notion of the metaverse. Metaverse is envisioned as the next iteration of the Internet in which the virtual and the real world are blended to materialize a highly immersive experience. Not surprisingly, perhaps, next‐generation training and education systems are concerned with methods to integrate themselves into metaverse environments. In particular, participants are looking for more interactive and flexible training while maintaining a degree of educational content and high quality for their training plans and interactive workflows. In this paper, we conducted research to explore the role of metaverse in employee training. To this end, we utilized a variant of PlaySAFe (i.e., a 3D game) to investigate its metaverse adoption and usage. A qualitative design was adopted, using semistructured interviews to explore practitioners' experiences using the new version of PlaySAFe. After having it played in an industrial setting, we interviewed a group of software practitioners to compare the actual and expected features. This research has explored the pros and cons of using the current technologies for the practical groundwork of SAFe training. Findings from this research suggest that the metaverse holds the potential to deliver improved practical alignment in training and education programs, but that at the present time, practitioners expect more metaverse compatible features. [ABSTRACT FROM AUTHOR]

Microwave breast cancer imaging (MWI) is an emerging non-invasive technology used to clinically assess the internal breast tissue inhomogeneity. MWI utilizes the variance in dielectric properties of healthy and cancerous tissue to identify anomalies inside the breast and make further clinical predictions. In this study, we evaluate our SAFE MWI system in a clinical setting. Capability of SAFE to provide breast pathology is assessed. Patients with BI-RADS category 4 or 5 who were scheduled for biopsy were included in the study. Machine learning approach, more specifically the Adaptive Boosting (AdaBoost) model, was implemented to determine if the level of difference between backscattered signals of breasts with the benign and malignant pathological outcome is significant enough for quantitative breast health classification via SAFE. A dataset of 113 (70 benign and 43 malignant) breast samples was used in the study. The proposed classification model achieved the sensitivity, specificity, and accuracy of 79%, 77%, and 78%, respectively. The non-ionizing and non-invasive nature gives SAFE an opportunity to impact breast cancer screening and early detection positively. Device classified both benign and malignant lesions at a similar rate. Further clinical studies are planned to validate the findings of this study. [ABSTRACT FROM AUTHOR]

Highlights: High Coulombic efficiency of over 99% for dendrite-free K||Cu cell after 820 cycles. Year-scale-cycling performance of organic PTCDI cathode over 2,100 cycles. Flexible device demonstration such as fibre cell still could operate when cut into three fibre cells. High degrees of freedom (DOF) for K+ movement in the electrolytes is desirable, because the resulting high ionic conductivity helps improve potassium-ion batteries, yet requiring support from highly free and flammable organic solvent molecules, seriously affecting battery safety. Here, we develop a K+ flux rectifier to trim K ion's DOF to 1 and improve electrochemical properties. Although the ionic conductivity is compromised in the K+ flux rectifier, the overall electrochemical performance of PIBs was improved. An oxidation stability improvement from 4.0 to 5.9 V was realized, and the formation of dendrites and the dissolution of organic cathodes were inhibited. Consequently, the K||K cells continuously cycled over 3,700 h; K||Cu cells operated stably over 800 cycles with the Coulombic efficiency exceeding 99%; and K||graphite cells exhibited high-capacity retention over 74.7% after 1,500 cycles. Moreover, the 3,4,9,10-perylenetetracarboxylic diimide organic cathodes operated for more than 2,100 cycles and reached year-scale-cycling time. We fabricated a 2.18 Ah pouch cell with no significant capacity fading observed after 100 cycles. [ABSTRACT FROM AUTHOR]

Animal protein is an important part of the human diet to support physical activities. The role of livestock as a source of animal protein requires adequate nutrition from feed to be able to produce optimally. The feed must be given in adequate amount of quality and quantity, safe feed (not toxic) is a must, and this cannot be separated from the contribution of animal husbandry nutrition science. Formulation of feed ingredients based on local feed and agro-industrial by-products into complete feeds in ruminant production is a strategy to meet the nutritional needs of ruminants so that they can produce optimally, efficiently, and environmentally friendly which ultimately produces products that are safe for human consumption. The success of this strategy has a greater opportunity through a corporate-based livestock approach, and through this approach, it is expected that the concepts of safe feed, safe food, and safe environment can be realized. Based on this phenomenon, animal husbandry nutrition science has proven its capability to contribute significantly to 1) produce livestock (ruminants) with efficient nutrition; 2) improve food safety and quality of food products originating from livestock for human consumption; 3) improve health status and welfare of livestock; and 4) reduce greenhouse gas emissions and the impact of livestock on environmental security. [ABSTRACT FROM AUTHOR]

The purpose of the research is to study certain aspects of transformation of corporate relations and corporate law, in the light of blurring of company boundaries and development of digital communications and startup culture. The results and conclusions are obtained based on general scientific and private scientific methods of research. Research studies examples of quasi-corporate and quasi-public structures created through (1) deferred share transfer agreements (SAFE), (2) crowdfunding agreements, (3) public market intermediary companies (SPAC), (4) exchanges for private companies. With the emergence of cross-border hybrid corporate structures at intersection of debt and equity, public and private financing, the current debates on the objectives of corporate law and the purpose of the corporation acquire a new perspective, as the very boundaries of the corporation become fluid. At the same time, decision-making procedures are mediated by third parties and digital technologies, with the prospect of conflict of interest, and are regulated, among other things, by standards emerging so to say from below. In the digital era, flexibility in the choice of elements of the structure allows to detach from the current state corporate regulation and attach to it in the right place and at the right time. It is concluded that the explosive growth of hybrid structures forms new areas of development of legal regulation by rejecting the dichotomy of soft and hard law. Among the vectors of transformation, the growing importance of private law unifications, the development of theoretical apparatus based on the concept of transnational law, the emergence of its subsystems, including lex corporatoria are noted. Among the tasks of lex corporatoria the formation of standards and customs in the field of corporate finance is also postulated as a regulatory framework for functioning of the hybrid structures under study.