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The purpose of the article is to establish the specificities of the formation of ideas about a person within the framework of the activities of the new urban religious communities of the Kama region, namely the Intercession Monastery and the Family of God. These communities combine features of folk religiosity, new religious movements, and the so-called historical sects. Such eclecticism makes it impossible to apply to the communities the established research apparatus for new religious movements (NRMs), formed by Western (B. Wilson, D. Stone, A. Barker) and Russian (L. N. Mitrokhin, E. A. Balagushkin, I. Kanterov and others) researchers and substantiates the need for this study conducted from both a different perspective and involving new research methodology. Both communities act as a closed community, which is expressed in the territorial and communication isolation of the residents of the communal estate, the practice of internal labor duties, and the idea of the group as a family. The study is based on interviews and correspondence with former members of both communities, analysis of materials from a closed group on a social network, and recordings of classes conducted by one of the group leaders. The theoretical basis of the work was K. Dobellard’s concept of the so-called patchwork religiosity, characteristic of an individual’s attitude towards religion in modern culture. The image of a person in both communities is constructed at two levels: through making changes to the traditional Christian idea of a person and at the level of religious and near-religious activities. It has been shown that innovations related to faith include the idea of a special status of community members compared to other people, as well as provisions about their special role in the struggle to save the world. The religious activities of the groups involve conducting adjusted Christian rituals (baptism, wedding), elements of mystical experience (mental struggle with evil and enemies in the Intercession Monastery), training seminars and sermons justifying the special role of followers of the teaching in society. Social interaction within communities is built on a strict selection of monks, leader control over the behavior of group members, a system of specific penalties, including ignoring offenders, public repentance, burial alive and expulsion from the brotherhood. The study concludes that the so-called new religious movements are in reality examples of traditional religious sects observed in Russia over the centuries. Their values, behavior, and the image of the person are archaic, however they also include additional external elements of secular culture.

Aim. To study the effect of multimorbidity on the risk of cardiovascular events (CVEs) in men with chronic coronary artery disease (CAD) after myocardial infarction (MI) and percutaneous coronary intervention (PCI).Material and methods. A total of 101 men with chronic CAD after MI and PCI were included in the study (mean age 60,5±6,1 years). Of these, taking into account the non-inclusion criteria and consent to examination, 2 following groups were formed: first (n=39) — men without CVEs; 2nd (n=39) — men with CVEs. In both groups, we studied the detection rate of grade I hypertension (HTN), class I obesity, hypercholesterolemia (HCE), and type 2 diabetes (T2D). The influence of HTN, obesity, HCE, and T2D on the risk of cardiovascular events was analyzed based on the calculation of contingency tables and Pearson's χ2, as well as odds ratios (OR) with 95,0% confidence intervals (CI). The follow-up period for patients averaged 3,6±0,5 years.Results. In men of group 2, compared with group 1 patients, grade I HTN, class I obesity, HCE were diagnosed more often in 1,3 (p=0,044), 1,4 (p=0,047), 1,2 (p=0,059) times, respectively. An increase in the risk of CVEs in men with chronic CAD, who underwent MI and PCI was associated with the detection of grade I HTN, class I obesity, HCE — OR 2,44 (CI: 1,88-6,75), OR 1,78 (CI: 1,56-4,62), OR 1,37 (CI: 1,11-4,17), respectively.Conclusion. Thus, the detection rate of grade I HTN, class I obesity and HCE in men with chronic CAD and CVEs at long-term follow-up after MI and PCI was significantly higher compared to patients with chronic CAD without CVEs after PCI. At the same time, the detection of grade I HTN, class I obesity and HCE were associated with an increased risk of cardiovascular events.

The article investigates the strategies of adapting to the changing social environment of city-based religious communities on the example of the case of the Intercession Commune (Pokrovskaya obitel’) in Perm. The community of believers led by activists developed as an Orthodox institution and subsequently evolved into a closed group with elements of mysticism and esotericism under the leadership of a charismatic female leader. The logic of the changes that have taken place is described through an analysis of interviews with former believers, private correspondence, and is performed using elements of the biographical method, materials from a closed group on a social network, records of classes conducted by the leader of the monastery, and photographs. The Intercession Commune as a community successfully evolves and adapts to the changing environment in response to the lawsuits filed against it. As a defensive strategy, community members chose active participation in patriotic projects, applying for grants issued by the local administration, and active appeal to Russian cultural traditions. Emphasis was placed on military education, which led to the creation of a special training center named after a former foreign intelligence officer. An additional way of legitimizing the community in the social space was participation in all-Russian patriotic actions (Immortal Regiment). All the above mentioned indicates a special mimicry of the group to appear as loyal to society, since it contradicts the ideas of withdrawal from social life, broadcast by the leader during internal seminars in the community. The chosen defensive strategy of the Intercession Commune allows us to say that religious associations that are not affiliated with official religious organizations are open to the active use of non-religious ways to assert themselves in society.

The use of available systems for obtaining structured data from primary medical information is based on the use of various technologies, including digital transformation of primary data for the formation of electronic health records. The purpose of the work was to outline the structure and benefits of using the RuPatient electronic health record (EHR), created to automate the work with medical data, digital character recognition and building an algorithm for communicating with patients. The created RuPatient EHR automates the processing of medical documents using image digitization and optical character recognition and the formation of a database. The developed program code that combines modules into a single web service is registered as intellectual property. The web service is a client-server application with the ability to access the interface through a browser from a smartphone, tablet, laptop, and personal computer. The service contains an interface part (Frontend), a functional part, with the possibility of expanding with separate modules (Backend), and databases for storing information about patients. The developed service provides standardization and digitalization of documents of patient-doctor visits and is a tool for convenient remote communication between a patient and a doctor via the built-in chat. The RuPatient EHR serves as a convenient tool for standardizing medical information in digital form and is designed to help the doctor and the patient in organizing treatment and preventive interaction.

The development of novel technologies using elements of artificial intelligence (AI) in medicine is addressed to practical clinical implementation and provision of key issues, including improvement in the use of routine clinical data, aimed at practical relevance, standardization, confidentiality and patient safety.Aim. To evaluate the effectiveness of the RuPatient electronic heart record (EHR) system in real clinical practice for extracting and structuring medical data.Material and methods. Extraction and recognition of data using EHR from various following sources: outpatient records, statements, routine medical reports, epicrisis and other structured and unstructured medical information based on the developed technology of intelligent text analytics, optical character recognition, for specified words and phrases, and the use of machine learning elements. A particular criterion for evaluating the effectiveness of EHR is the time spent on filling out electronic medical records compared to real clinical practice.Results. The time of entering and processing information by the recognition system of medical documentation included in the RuPatient EHR was shorter than in standard practice (20,3±1,4 minutes, 25,1±1,5 minutes, respectively, p

RuPatient health information system (HIS) is a computer program consisting of a doctor-patient web user interface, which includes algorithms for recognizing medical record text and entering it into the corresponding fields of the system.Aim. To evaluate the effectiveness of RuPatient HIS in actual clinical practice.Material and methods. The study involved 10 cardiologists and intensivists of the department of cardiology and сardiovascular intensive care unit of the L. A. Vorokhobov City Clinical Hospital 67 We analyzed images (scanned copies, photos) of discharge reports from patients admitted to the relevant departments in 2021. The following fields of medical documentation was recognized: Name, Complaints, Anamnesis of life and illness, Examination, Recommendations. The correctness and accuracy of recognition of entered information were analyzed. We compared the recognition quality of RuPatient HIS and a popular optical character recognition application (FineReader for Mac).Results. The study included 77 pages of discharge reports of patients from various hospitals in Russia from 50 patients (men, 52%). The mean age of patients was 57,7±7,9 years. The number of reports with correctly recognized fields in various categories using the program algorithms was distributed as follows: Name — 14 (28%), Diagnosis — 13 (26%), Complaints — 40 (80%), Anamnesis — 14 (28%), Examination — 24 (48%), Recommendations — 46 (92%). Data that was not included in the category was also recognized and entered in the comments field. The number of recognized words was 549±174,9 vs 522,4±215,6 (p=0,5), critical errors in words — 2,1±1,6 vs 4,4±2,8 (p

Aim. To study the significance of clinical parameters and cardiovascular risk factors (CVR) for restenosis development at long terms after percutaneous coronary intervention (PCI) as a possible displaying of neoatherosclerosis development (NA).Material and methods. Totally, 155 patients after coronary stents implantation, bare and drug eluting, who then, according to clinical profile, underwent second (follow-up) coronary arteriography (CAG) and/or PCI at the timeline of ~4 years. All patients were selected to groups according to restenosis development and time spent before the second procedure (before and after 9 months): group 1 (n=67) — short term follow-up (9 months) and absence of restenosis; group 4 (n=19) — long term and restenosis (probable NA).Results. Comparison of clinical data and CVR showed that hypodynamia/ abdominal obesity were more prevalent in the group 1 — 20,90%/11,94%, respectively, and group 3 — 13,95%/11,63%, than in group 4 — 5,26%/5,26% and were completely absent in group 2 (p=0,011). Second PCI at the follow-up was done significantly more commonly in restenosis: gr.1/gr.3 — 68,66%/58,14%, gr.2/gr.4 — 84,62%/89,47% (p=0,028). Diagnosis “acute coronary syndrome” in “follow-up CAG/PCI” was significantly more common in delayed restenosis as a display of possible NA — group 4 — 31,58%, comparing to other groups of patients: group 1 — 14,93%, group 2 — 11,54%, group 3 — 4,65% (p=0,043). Other risk factors: arterial hypertension, hypercholesterolemia, diabetes mellitus, insulin dependency, chronic renal failure, smoking, alcohol abuse, family cardiovascular anamnesis, body mass index, — did not show statistically significant differences between the groups.Conclusion. Neoatherosclerosis as the possible element of restenosis at long terms of coronary stenting, in difference from earlier restenosis, presented with more frequent acute clinical conditions. There were no significant difference by CVR factors.

Achievements of interventional cardiology in the treatment of coronary artery disease are based on coronary balloon angioplasty with implanting bare metal stents and drug eluting stents. Questions of complications such as early stent thrombosis and restenosis of stent were solved in a considerable degree. However, with the lengthening of the followup period, the problem of late complications became obvious. Except endothelization and fibromuscular proliferation in stented coronary arteries the process of plaque formation has an important influence on later complications in follow-up period more than one year. This process was defined as neoatherosclerosis. This is verified by clinical manifestations of the disease, histological studies, angioscopy, intravascular ultrasound and optical-coherence tomography in stented patients. Dynamic observation of the condition in stentedcoronary arteries showed multistep proliferation with restenosis, its regression, and neoatherosclerosis development. Evidences of neoatherosclerosis formation in stented coronary arteries are considered in this review.

Aim. To study the life quality parameters in interventional and conservative treatment strategies in patients with stable angina at delayed follow-up periods.Material and methods. Totally 146 patients included with stable angina: main group – 102, comparison group – 44 patients. To the first the stenting or angioplastics of coronary arteries provided, to the second – just drug therapy. Mean follow-up period was 3,6±1,3 years. Life quality parameters were measured in patients.Results. It is shown that in men and women of the main group the physical functionality parameter was higher than in comparison group – by 23,1% and 18,2%, resp. (both with p

To study the long-term results of coronary arterial stenting in relation to the baseline clinical and angiographic findings and the presence of acute coronary syndrome at the moment of a procedure, the authors made a retrospective comparison of groups of patients undergone balloon angioplasty with a stent being inserted. The findings indicate that while choosing the tactics of treatment for patients with coronary heart disease (CHD) and assessing the risk of development of poor outcomes of coronary stenting, it is necessary to take into account a combination of factors significantly affecting the occurrence of coronary events and the development of restenosis after surgery (smoking, acute coronary syndrome at the moment of a procedure, serum triglyceride levels, extent of coronary bed affliction, type of stenosis, diameter of a revas-cularized vessel) and to apply, where possible, the minimal effective exposure principle to achieve the optimal result of a procedure.

Aim. To study long-term results of coronary artery (CA) stenting, according to baseline clinical and coronaroangiography (CAG) data. Material and methods. The study included 66 males who underwent coronary stent implantation. One to three years later, all participants were retrospectively divided into several groups. Patients without coronary events (CE) comprised CE- Group (n=44), patients with CE – CE+ Group (n=22). Second CAG was performed in 49 patients with 56 stent-implanted CA. CAG signs of restenosis were not found in 35 stenting cases (Restenosis- Group), being registered in 21 stenting cases (Restenosis+ Group). Stepwise multiple regression was used for analyzing the results obtained. Results. After stent implantation, CE risk was affected by smoking status, number of hemodynamically significant stenoses, low diameter of stented CA, balloon inflation time, and minimal effective intervention (MEI) level. Restenosis risk was linked to unstable angina presence, serum triglycerides level, stenosis type, MEI, and low increase in CA diameter after stenting. Conclusion. In selecting treatment tactics for coronary heart disease patients, and assessing the risk of adverse outcomes after CA stenting, a complex of factors affecting CE and restenosis rates should be taken into account, as well as minimally traumatic technique of coronary stenting should be used.

To assess influence of the natural fat tissue levels of lipophylic antioxidants and polyunsaturated fatty acids (PUFA) in patients with acute myocardial infarction (MI), on coronary heart disease (CRD) progression. Sixty patients, who had MI in 1991-92, were surveyed and included into the main group of EURAMIC study. According to the variants of CHD progression (death, recurrent MI, stroke, myocardial revascularization), all participants were divided into two groups: 25 individuals without CHD progression (Pr-), and another 35 - with CHD progression (Pr+). To study complex influence of traditional CVD risk factors, lipophylic antioxidants and PUFA levels on the long-term prognosis, as well as for assessing the individual input of each variable, multiple regression analysis was used. The results obtained have demonstrated the following: 1. Carotinoid and PUFA levels in fat tissue of acute MI patients did influence the long-term prognosis of CHD. 2. In patients with MI, decreased level of low-density lipoprotein cholesterol was a significant predictor of poor prognosis. 3. In initially normostenic MI patients, further increase in body mass index associated with worse CHD prognosis.

Цель. Определить значимость различных стентов с и без лекарственного покрытия на развитие неоатеросклероза при длительных сроках наблюдения после операции чрескожного коронарного вмешательства (ЧКВ). Материал и методы. В анализ был включен 141 пациент после имплантации стентов с лекарственным покрытием и без такового, а также выполнением очередной (follow-up) коронароангиографии (КАГ) и/или ЧКВ на ранних и отдаленных этапах наблюдения после инициативной процедуры (index-ЧКВ). Все повторные исследования выполнялись строго в связи с ухудшением клинической картины пациента: возникновение симптомов стабильной стенокардии, нестабильной стенокардии, острого инфаркта миокарда (ИМ). Все больные были подразделены на группы в зависимости от типа стента, установленного на index-ЧКВ, и времени до follow-up КАГ и/или ЧКВ (

Цель. Сравнить показатели сократительной функции миокарда у больных ишемической болезнью сердца (ИБС) на отдаленных сроках после чрескожного коронарного вмешательства (ЧКВ). Материал и методы. В исследование включили 60 больных ИБС (средний возраст 63,2±6,8 года) с приступами стабильной стенокардии II-III функционального класса. Было сформировано 2 группы: 1-я - 30 больных, имеющих фракцию выброса (ФВ) левого желудочка (ЛЖ)50%. Исследование было одобрено Этическим комитетом Тверского государственного медицинского университета (г. Тверь). Критерием включения в работу служил факт выполнения коронароангиографии (КАГ), баллонной ангиопластики и стентирования коронарных артерий (КА) в отделении рентгенэндоваскулярных методов диагностики и лечения Государственного научно-исследовательского центра профилактической медицины (г. Москва). Проведены: изучение жалоб и анамнеза; ЭКГ; ЭхоКГ; допплерокардиография; холтеровское мониторирование ЭКГ; велоэргометрия. Длительность наблюдения после ЧКВ составила в среднем 3,6±1,2 года. При ЭхоКГ оценивались: толщина межжелудочковой перегородки в диастолу (ТМЖПд); толщина задней стенки ЛЖ в диастолу (ТЗСЛЖд); конечный систолический размер (КСР) ЛЖ; конечный диастолический размер (КДР) ЛЖ; конечный систолический объем (КСО) ЛЖ; конечный диастолический объем (КДО) ЛЖ. ФВ ЛЖ (в %) рассчитывалась по формуле: ФВ ЛЖ=(КДО-КСО)/КДО¥100%. Фракцию укорочения среднего слоя (FSсредн.) рассчитывали по формуле: FSсредн. (в %) = [(КДРЛЖ+ТМЖПд/2+ТЗСЛЖд/2(КСРЛЖ+Tсредн./2)]/(КДРЛЖ+ТМЖПд/2+ТЗСЛЖд/2)¥100, где: Тсредн. - толщина среднего слоя. Для сравнения показателей был применен U-критерий Манна-Уитни. Для оценки связи между переменными использовали R-критерий корреляции Спирмена. Результаты. Параметры КДР ЛЖ, КДО ЛЖ, КСР ЛЖ и КСО ЛЖ у пациентов 1-й группы были выше, чем во 2-й (на 10,2 и 24,1%; на 24,2 и 67,3% соответственно; все p