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Reaction of two-fold excess of diethyl 3-methyl-1,2-butadienylphosphonate with 1,10-diaza-18-crown-6 leads to the formation of an adduct whose molecule includes two 1-phosphoryl-3-methyl-2-butene fragments bound together by a crown bridge with the anti location of organophosphorus groups relative to the macrocycle plane. The 1,2-multiple bond of the phosphonate is involved in the reaction. Extraction properties of the diphosphorylated crown ether toward alkali metal picrates were studied.

The results of experiments devoted to studying the excitation of the promising nuclear fusion reactions 6Li(d, α)4He, 3He(d, p)4He, 11B(p, 3α), and 7Li(p, α)4He, along with the standard reaction D(d, n)3He, in picosecond laser plasmas are presented. For the first time, it was shown that these reactions may proceed at a moderate laser-radiation intensity of 2 × 1018 W/cm2, the respective yield being 2 × 103 to 105 per laser pulse. A brief survey of the main processes responsible for the generation of fast electrons and fast ions (protons) at the front surface of the target and for the excitation of nuclear fusion reactions is given. The calculated and experimental results on the yield from nuclear fusion reactions in picosecond laser plasmas are compared. The possibilities for optimizing the yield from the promising fusion reactions excited in femto- and picosecond laser plasmas are discussed.

The reaction of 1,2-diaminoethane with vinylphosphonate occurs as the addition of the amino group to the β -carbon atom of the unsaturated substrate to give 1:1 and 1:2 adducts. The nucleophilic addition of 2-aminoethanol at the β -position of the double bond of vinylphosphonates involves only the amino group and leads to the formation of hydroxy β -aminoethylphosphonates or zwitterions depending on conditions.

The article is devoted to contribution of major general (rear Admiral. - navy) of medical service Nikolay Grigoryevich Ryzhman (1944-2005), the chief of the medical service of the Northern fleet (1991-1999), to development of naval medicine, who would have turn 70 years this September. The constant analysis, and experience generalization of the medical services of the fleet connections and associations and aspiration to provide fighting capacity for the fleet crew - were a keynote of Ryzhman's activity concerned development and deployment of the new forms and methods of medical support and searching of ways to increase crew efficiency. The implemented methods and forms of organization of the medical support and scientific development of the medical support are used even now in the practical activities of the medical service of the Northern fleet.

Dialkyl 3-methylbuta-1,2-dienyl- and vinylphosphonates take up imidazole at the β-carbon atom in the unsaturated fragment to give the corresponding β-(1H-imidazol-1-yl)alkenyl-and alkylphosphonates.

Dialkyl 3-methylbuta-1,2-dienyl- and vinylphosphonates take up imidazole at the β-carbon atom in the unsaturated fragment to give the corresponding β-(1H-imidazol-1-yl)alkenyl-and alkylphosphonates.

Treatment of the patients with long tubular bone defects is the difficult problem. At present the most widespread bone graft methods allow to achieve the result but not always satisfy physicians and patients. The use of revascularized bone autografts opens the new opportunities in the treatment of such patient category. Case records of 34 patients with long tubular bone large defects who underwent the bone graft with revascularized bone autograft were analyzed. Good and satisfactory anatomical and functional results were achieved (follow-up was up to 10 years), some complications and possible methods of their prevention were analyzed.

Mixing an excess of 3-methyl-1,2-butadienylphosphonate with 1,2-diaminoethane, 1,2-diaminopropane, or 4,7,10-trioxa-1,13-tridecandiamine leads to the formation of bis-(aminoalkenylphosphonates).

High reactivity of allene derivatives of the tetracoordinated phosphorus atom in the nucleophilic addition reactions opens a possibility of the effective synthesis on their basis of new β-amino-functionalized organophosphorus compounds. The latter are promising for the use as biologically active compounds, metal extractants, and membrane carriers [1–3]. In this work the results of the study of the reaction between 3-methyl-1,2-butadienylphosphonates I and 4,9-dioxa-1,12-dodecanediamine II are presented. On mixing diamine II with two-fold excess of phosphonate I the oily adduct III was obtained. It was washed with СН2Cl2 to the constant value of nD. In the IR spectra of compound III the stretching vibrations band of allene triad (1955 cm) is absent, and strong bands at 1200 (Р=О), 1590 (С=С), 3300– 3500 cm (NH) appear. The absence of the proton signals of phosphorus methylene group with the spinspin coupling constant JPH 20–22 Hz and of the proton signals of two methyl groups at the double bond makes it possible to ascribe to compounds IIIа and IIIb the enamine structure. Compounds IIIа and IIIb possess effective antimycotic activity.