Search

Background: Screening for anemia in children’s under five years of age using palmar pallor and Digital hemoglobinometer by finger prick method. Methodology: A total of 200 subjects were enrolledfrom outpatient department of ACS Medical College. Children of the age group 6 months to 5 years were considered in the study. Out of the total, 84 were boys and 116 were girls. Blood sampleswere collected from the subjects using a finger prick method and measured using Digital Haemoglobinometer. Data was collected and result was analysed using SPSS software. Results: Out of the 200 children examined, 91 (45%) were found to be no palmar pallor, 102 (51%) were some palmar pallor and 7 (4%) were severe anemia (severe palmar pallor),Whereas using Digital Haemoglobinometer, 64 (34%) no anemia (Hb ≥11 mg/dL), 115 (57%) children’s were found to beanemic (Hb

Lactic acid bacteria (LAB) are ubiquitous, Gram-positive, fermentative bacteria, which are regarded as safe for both humans and the environment. The present study aimed to evaluate the biocontrol efficiency of LAB isolated from different natural ecosystems against fungal pathogens. A total of 30 LAB was isolated from rhizosphere soil and phyllosphere sample of Solanaceous crop viz., Brinjal, Capsicum, Chilli, Tomato, whey, and sauerkraut out of them 14, 9, 4 and 3 lactic acid bacteria (LAB) were isolated from rhizosphere soil & phyllosphere sample of Solanaceous crops, whey and Sauerkraut respectively. The biocontrol ability of LAB isolates were tested against fungal plant pathogens such as Fusarium oxysporum, Pythium aphanidermatum, Sclerotium rolfsi, Rhizoctonia solani, Alternaria sp. agar well diffusion assay and mycelial growth inhibition in liquid culture. The results indicated that the isolates LAB 4, LAB 10, LAB 22, LAB 24 and LAB 29 were prominent in inhibiting the growth of most of the pathogens. Molecular characterization of selected LAB isolates revealed that LAB 4, LAB 10, LAB 22, LAB 24 belongs to Lactobacillus plantarum and LAB 29 belong to Leuconostoc mesentroides.

This article provides a comprehensive review of recent developments in deep learning, including both its theoretical underpinnings and its innovative practical applications. This article provides a historical overview of the significant uses of deep learning algorithms. Comparing the deep learning approach with more traditional algorithms, this article highlights the method's advantages and benefits. This includes the deep learning approach's layer-based hierarchy and nonlinear operations. The state-of the-art review also gives a high-level explanation of deep learning's advantages and growth in popularity. With deep learning, meaningful hierarchical linkages within the data can be discovered algorithmically without the need for painstaking hand-crafting of features, which is especially useful in the era of medical big data. We discuss the state-of-the-art in medical picture segmentation, localization, detection, and registration, as well as its most important applications.

Content analysis is an effective research tool to study the extent of information covered in farm magazines, which act as a comprehensive guide for farmers. The aim of the study is to analyze the coverage, readability ease, mode of presentation, and type and level of infographics published in the Tamil bimonthly magazine Pasumai Vikatan. The magazine was purposefully selected based on regional preferences and popularity. A total of 619 articles covered across 64 editions from 2019 to 2021 were considered for the sample study to analyze the basic objective of the extent of farm information, readability ease and also the infographics covered. Inferential statistics were used to analyze percentage and frequency. The research revealed that 64.63 percent of the articles covered in the magazine were based on economics of returns in the past three years followed by articles related to organic farming (35.83 percent) and crop production aspects (35.13 percent). Further, the Flesch Kincaid reading ease was analyzed and the results indicated that the ease of articles ranged between very easy and standard and could be understood easily even by young readers. With respect to format, the articles were presented predominantly in series format (70.24 percent) followed by current news items pertaining to the agricultural sector (66.31 percent). The study also identified that the usage of infographics was sparse without much textual information. The authors recommend the usage of modern e-data tools for newsgathering during the pandemic period and also suggest deeper coverage of other recent areas in agriculture and allied sectors.

Natural products have become a promising therapy for many pathogenic infectious conditions. In the present study, leaves of P. cablin were extracted using Hexane and ethyl acetate. Leaf Ethyl acetate extract showed significantly better antimicrobial activity against both Staphylococcus aureus 6538 (Gram-positive) (SA) and Klebsiella pneumonia ATCC 27,736 (Gram-negative) bacteria compared to the Hexane extract and was subjected to phytochemical analysis and chromatographic seperation. Phytochemical analysis of P. cablin leaf EtOAc extract showed the presence of Tannins, Flavanoids and Terpenoids. Subjecting the EtOAc leaf extract to column chromatographic separation resulted in the isolation of a trimethoxy flavone, pachypodol.

Transition metal dichalcogenides (TMDCs) are two dimensional nanomaterials made up of a monolayer of transition metal atoms sandwiched (X-M-X) between two layers of chalcogen atoms in a hexagonal lattice. Molybdenum di sulfide (MoS2) have attracted much attention among the TMDCs family and is a suitable electrode material for supercapacitors. It has remarkable physical and chemical properties such as large surface area, sheet like structure, superior capability and lower rates of cyclic induced degradation. However, MoS2 suffers from lower electronic conductivity that limits its energy storage. Hence the conducting polymer, polyaniline is doped with the MoS2 to overcome the deficiencies and to enhance the electrochemical performance. A novel microwave assisted method is implemented to synthesize MoS2/PANI nanocomposites for the strategy of supercapacitors. The microwave assisted processing of MoS2/PANI nanocomposites provides several advantages than the conventional heating method such as tuning the physiochemical properties as reduction of impurity, mono dispersivity in the morphology that results in enhancing the electrochemical performance. The phase purity, homogeneity, and functional groups present in the MoS2/PANI nanocomposites are synthesized and characterized by X-ray diffraction (XRD), Field Emission Scanning Electron microscope (FESEM), High Resolution Transmission Electron Microscope (HR-TEM), Fourier Transform infrared spectroscopy (FT-IR), UV–Visible (UV–Vis) absorption spectroscopy and Raman spectroscopy. The optimized MoS2 /PANI nanosheets exhibits a high specific capacitance of 348 F/g at 0.5 A/g and MoS2/PANI nanocomposites retains 89.21% of its initial specific capacitance even after 2000 cycles. Hence the strategy of microwave assisted synthesis of MoS2/PANI nanocomposites improve the electrochemical performance of two dimensional MoS2 based electrode materials for energy storage.

The chemical compound 6-hydromethyl-4-methoxy-4- methoxytetrahydro-pyran-2, 3, 5-triol (C7H14O6), was derived from the ethanol extract of Senna auriculata flower via GC-MS. FT-IR and NMR characterization of the compound support covalent bonding information and degree of degeneracy, respectively. 3D molecular structure was optimized to enhance the accuracy of computations. MEP, NBO, HOMO-LUMO, and Mulliken charge distribution studies provide details like reactive sites, electron density dislocation, and molecular interactions, charge transfer within the molecule and frontier orbital energies, electron density on the individual atom, and these were computed using hybrid B3-LYP quantum level with 6-311++G(d, p) basis set. Thermodynamic properties such as heat capacity, entropy, enthalpy, and their relation with temperature changes for the title molecule were also analyzed using THERMO.PL software. Non-linear optical properties namely polarizability, first-order hyperpolarizability, and electronic dipole moment have also been computed at B3-LYP level with 6-311++G (d, p) basis set. Docking simulation was initiated on the title molecule using Autodock 4.2 software and found to be an excellent inhibitor of ALR2, an enzyme.

Transition metal dichalcogenide and polyaniline doped zinc oxide nanocomposites influence the transition probabilities and electronic structure. In present study, the various concentrations of MoS2/PANI/ZnO nanocomposites are synthesized by microwave assisted method. These nanocomposites are characterized by using XRD, FESEM, HRTEM and FT-IR. The XRD results revealed an average crystallite size of synthesized nanocomposites, which was found to be 19-24 nm. The electrochemical properties of the nanocomposites are studied through the CV, EIS and GCD for the application of supercapacitor as an active electrode material. The MoS2/PANI/ZnO nanocomposites exhibited a specific capacitance of 577 F g-1 and also retained 90% of its initial specific capacitance even after 5000 cycles. Hence MoS2/PANI/ZnO nanocomposites have potential application for energy storage applications.

Idiopathic basal ganglia calcification (IBGC) or primary familial brain calcification is a rare genetic condition characterized by an autosomal dominant inheritance pattern and the presence of bilateral calcifications in the basal ganglia, thalami, cerebellum and cerebral subcortical white matter. The syndrome is genetically and phenotypically heterogeneous. Causal mutations have been identified in four genes: SLC20A2, PDGFRB, PDGFB and XPR1. A variety of progressive neurological and psychiatric symptoms have been described, including cognitive impairment, movement disorders, bipolar disorder, chronic headaches and migraine, and epilepsy. Here we describe a family with a novel SLC20A2 mutation mainly presenting with neurological symptoms including cortical myoclonus and epilepsy. While epilepsy, although rare, has been reported in patients with IBGC associated with SLC20A2 mutations, cortical myoclonus seems to be a new manifestation.

Indian organized retail market is growing at a fast pace due to the boom in the India retail industry. In 2005, the retail industry in India amounted to Rs 10,000 billion accounting for about 10% to the country’s GDP. The organized retail market in India out of this total market accounted for Rs 350 billion which is about 3.5% of the total revenues. Traditionally the retail industry in India was largely unorganized, comprising of drug stores, medium, and small grocery stores. Most of the organized retailing in India have started recently and is concentrating mainly in metropolitan cities. The growth in the Indian organized retail market is mainly due to the change in the consumer’s behavior. This change has come in the consumer due to increased income, changing lifestyles, and patterns of demography which are favorable. Now the consumer wants to shop at a place where he can get food, entertainment, and shopping all under one roof. This has given Indian organized retail market a major boost. Retail market in the organized sector in India is growing can be seen from the fact that 1500 supermarkets, 325 departmental stores, and 300 new malls are being built. Many Indian companies are entering the Indian retail market which is giving Indian organized retail market a boost. One such company is the Reliance Industries Limited. It plans to invest US$6billionintheIndianretailmarket by opening 1000 hypermarkets and 1500 supermarkets. Pantaloons are another Indian company which plans to increase its retail space to 30 million square feet with an investment of US$ 1 billion. Bharti Telecoms an Indian company is in talks with Tesco a global giant for a £ 750 million joint venture. A number of global retail giants such as Walmart, Carrefour, and Metro AG are also planning to set up shop in India. Indian organized retail market will definitely grow as a result of all this investments. Indian organized retail market is increasing and for this growth to continue the Indian retailers as well as government must make a combined effort. The Indian retail industry has emerged as one of the most dynamic and fast-paced industries due to the entry of several new players. Total consumption expenditure is expected to reach nearly US$ 3,600 billion by 2020 from US$ 1,824 billion in 2017. It accounts for over 10 per cent of the country’s Gross Domestic Product (GDP) and around 8 per cent of the employment. India is the world’s fifth-largest global destination in the retail space. India’s retail market is expected to increase by 60 per cent to reach US$ 1.1 trillion by 2020, on the back of factors like rising incomes and lifestyle changes by middle class and increased digital connectivity. Online retail sales are forecasted to grow at the rate of 31 per cent year-on-year to reach US$ 32.70 billion in 2018. Indian market has high complexities in terms of a wide geographic spread and distinct consumer preferences varying by each region necessitating a need for localization even within the geographic zones. India has highest number of outlets per person (7 per thousand) Indian retail space per capita at 2 sq ft (0.19 m2)/ person is lowest in the world Indian retail density of 6 percent is highest in the world. 1.8 million Households in India have an annual income of over 4.5 million (US$62,615.70). While India presents a large market opportunity given the number and increasing purchasing power of consumers, there are significant challenges as well given that over90%oftradeisconductedthrough independent local stores. Challenges include: Geographically dispersed population, small ticket sizes, complex distribution network, and little use of IT systems, limitations of mass media and existence of counterfeit goods. India is expected to become the world’s fastest growing e-commerce market, driven by robust investment in the sector and rapid increase in the number of internet users. Various agencies have high expectations about growth of Indian e-commerce markets. Luxury market of India is expectedtogrowtoUS$30billionby the end of 2018 from US$ 23.8 billion 2017 supported by growing exposure of international brands amongst Indian youth and higher purchasing power of the upper class in tier 2 and 3 cities, according to Assoc ham. The Indian retail trading has received Foreign Direct Investment (FDI) equity inflows totaling US$ 1.42 billion during April 2000–June 2018, according to the Department of Industrial Policies and Promotion (DIPP). With the rising need for consumer goods in different sectors including consumer electronics and home appliances, many companies have invested in the Indian retail space in the past few months. Beckons, a South Korean designer brand is set to enter the Indian market with an investment of about Rs 1.00 billion (US$ 14.25 million) and open 50 stores by June 2019. Wal-Mart Investments Cooperative U.A has invested Rs 2.75 billion (US$ 37.68 million) in Wal-Mart India Pvt Ltd. The Government of India has taken various initiatives to improve the retail industry in India. The Government of India may change the Foreign Direct Investment (FDI) rules in food processing, in a bid to permit e-commerce companies and foreign retailers to sell Made in India consumer products. Government of India has allowed 100 per cent Foreign Direct Investment (FDI) in online retail of goods and services through the automatic route, thereby providing clarity on the existing businesses of e-commerce companies operating in India. E-commerce is expanding steadily in the country. Customers have the ever increasing choice of products at the lowest rates. E-commerce is probably creating the biggest revolution in the retail industry, and this trend would continue in the years to come. India’s e-commerce industry is forecasted to reach US$ 53 billion by 2018. Retailers should leverage the digital retail channels (e-commerce), which would enable them to spend less money on real estate while reaching out to more customers in tier-2 and tier-3 cities. It is projected that by 2021 traditional retail will hold a major share of 75 per cent, organized retail share will reach 18 per cent and e-commerce retail share will reach 7 per cent of the total retail market. Nevertheless, the long- term outlook for the industry is positive, supported by rising incomes, favorable demographics, entry of foreign players, and increasing urbanization.

ObjectiveTo explore the phenotypic spectrum of RHOBTB2-related disorders and specifically to determine whether patients fulfill criteria for alternating hemiplegia of childhood (AHC), we report the clinical features of 11 affected individuals.MethodsIndividuals with RHOBTB2-related disorders were identified through a movement disorder clinic at a specialist pediatric center, with additional cases identified through collaboration with other centers internationally. Clinical data were acquired through retrospective case-note review.ResultsEleven affected patients were identified. All had heterozygous missense variants involving exon 9 of RHOBTB2, confirmed as de novo in 9 cases. All had a complex motor phenotype, including at least 2 different kinds of movement disorder, e.g., ataxia and dystonia. Many patients demonstrated several features fulfilling the criteria for AHC: 10 patients had a movement disorder including paroxysmal elements, and 8 experienced hemiplegic episodes. In contrast to classic AHC, commonly caused by mutations in ATP1A3, these events were reported later only in RHOBTB2 mutation–positive patients from 20 months of age. Seven patients had epilepsy, but of these, 4 patients achieved seizure freedom. All patients had intellectual disability, usually moderate to severe. Other features include episodes of marked skin color change and gastrointestinal symptoms, each in 4 patients.ConclusionAlthough heterozygous RHOBTB2 mutations were originally described in early infantile epileptic encephalopathy type 64, our study confirms that they account for a more expansive clinical phenotype, including a complex polymorphic movement disorder with paroxysmal elements resembling AHC. RHOBTB2 testing should therefore be considered in patients with an AHC-like phenotype, particularly those negative for ATPA1A3 mutations.

Implementation of a new algorithm with Shunt Active Filter’s Various Current Control technique is proposed.A non-linear load, three-phase, six-pulse, resistive load converter is taken into account. In order to generate switching pulses which lead to the generation of current, four different switching methods are used. Due to its simplicity, rapid and precise implementation response, Hysteresis Current Control is commonly used. The key problem, therefore, is its variable switching frequency, resulting in additional power dissipation and the incorporation into the existing framework of high-frequency harmonics.In this paper,an Adaptive Hysteresis Current Control has been implemented to address the issue, generating hysteresis bandwidth that spontaneously helps in smoother and continuous frequency.In contrast to three other control methods, the cumulative,this approach has decreased the rate of Gross Harmonic Distortion. The architecture theory of the suggested SAF applying the PI- related optimization method is being evaluated via MATLAB and findings demonstrate the efficiency of the suggested technique.

Automated health diagnostic system uses Internet of Things (IoT) for remote diagnosis, constant patient monitoring and treatment. Monitoring health status of patients in rural areas is difficult task. Patients need to be monitored, and their health status has to be informed periodically (Venkateswarlu DS, Verma KS, Murthy KSRA in e-health networking to cater to rural health care and health care for the aged [1]). Hence, we propose automated healthcare system by which we can measure various health parameters and predict the disease. Our system utilizes the symptoms given by user through graphical user interface (GUI) and predicts the common diseases with the help of machine learning techniques. It also has a wearable monitoring system which is embedded with various sensors to measure health parameters like body temperature, step counting and blood oxygen levels. ECG module is used to measure heart parameters and is used for prediction of various heart-related diseases with help of algorithm. All the data is collected, stored and transmitted with the help of Wi-Fi module to a common device. The data which is stored using healthcare system can be accessed easily with the help of application login. Thus, IoT-based healthcare system effectively uses Internet to monitor patient health status and gives alert message in emergency cases.

Brain arteriovenous malformations (bAVM) arise as congenital or sporadic focal lesions with a significant risk for intracerebral hemorrhage (ICH). A wide range of interindividual differences is present in the onset, progression, and severity of bAVM. A growing body of gene expression and polymorphism-based research studies support the involvement of localized inflammation in bAVM disease progression and rupture. In this review article, we analyze the altered responses of neural, vascular, and immune cell types that contribute to the inflammatory process, which exacerbates the pathophysiological progression of vascular dysmorphogenesis in bAVM lesions. The cumulative effect of inflammation in bAVM development is orchestrated by various genetic moderators and inflammatory mediators. We also discuss the potential therapies for the treatment of brain AVM by targeting the inflammatory processes and mediators. Elucidating the precise role of inflammation in the bAVM growth and hemorrhage would open novel avenues for noninvasive and effectual causal therapy that may complement the current therapeutic strategies.

This article dealt the conception of compactness under nano ideal α generalised closed sets (nIαg-compact spaces) in nano ideal topological spaces. nIαg-compact spaces under nIαg-continuous and irresolute mappings were exhibited. nIαg-Lindelof space and its relation with some existing spaces were discussed. Relationship of nIαg-compact space with nIαg-Hausdroff space was also been explained.

This paper emphasizes on the development of a new predictive modeling based on interval valued Markov integrated Rhotrix optimization using genetic algorithm. Interval valued partitioning was used for development of predictive modeling of future behavior based on the most important genetic algorithm optimizer. The proposed predictive model is trained and tested on the datasets taken from multiple websites for short and decadal long weather prediction. The initialization of the weather parameters is done in first phase using interval valued Markov integrated Rhotrix predictive model. Optimized estimation of weather parameters is performed in second phase using Genetic Algorithm improving the error in predictive modeling. The experimental result shows that the increase in the greenhouse gases per year is 1.915 ppm, the average increase in temperature for each year is 0.055 ℃ and the average increase in temperature for each year due to the impact of greenhouse gases is −0.137 ℃. Further it was also analyzed and estimated that for 2020–2029, the average concentration of greenhouse gases will be 414.1015 ppm, the average increase in temperature will be 13.696 ℃, the average increase in temperature due to greenhouse gases will be 13.6413 ℃. The actual global temperature was computed by adding 12.7 ℃ (20th century global average temperature) to the temperature anomaly.

Composites of cerium oxide ( $$\hbox {CeO}_{2}$$ ) and magnesium aluminate ( $$\hbox {MgAl}_{2}\hbox {O}_{4}$$ ) were prepared by the molten salt synthesis (MSS) method at 1130 K. The composite samples were named as MA, MAC0.07 and MAC0.14 (at $$\hbox {CeO}_{2}$$ : 0, 0.07 and 0.14 g in $$\hbox {MgAl}_{2}\hbox {O}_{4}$$ , respectively) and these were characterized by X-ray diffraction and energy-dispersive X-ray analyses. It is seen that the microstructure of the composite samples are quite similar except for a small increase in particle size. The energy-dispersive X-ray analyses provide the presence of concentration of Ce, Mg, Al and O in the composite. Scanning electron microscope, coupled with energy-dispersive X-ray analysis (SEM-EDAX) was used to identify the morphology, microstructure and elemental composition of the prepared samples. The decomposition and dissociation reactions of the precursors were determined using differential thermal and thermogravimetric analysis (TGA). A lone pair of the electron state was identified from the electro paramagnetic resonance spectrum. An optical energy band gap of 3.3 eV was calculated from the UV–Vis absorbance spectra. The gas response to changes in oxygen ( $$\hbox {O}_{2}$$ ), carbon monoxide (CO) (at 0.5, 1.0 and 1.5 bar) and ethanol (at 50 and 100 ppm) was quantitatively analysed in all the samples at different operating temperatures (300–500 K). The magnitude of the temperature varied linearly regardless of the gas pressure inside the chamber, by increasing the supply in the heating pad, mounted below the sensor sample. The composite samples indicate a good response to different gases with detection of the smallest change in gas pressure.