193 results on '"S. Gumenyuk"'
Search Results
2. Alkaline phosphatase (alp) levels in multiple myeloma and solid cancers with bone lesions: Is there any difference?
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O. Annibali, M.T. Petrucci, D. Santini, V. Bongarzoni, M. Russano, F. Pisani, O. Venditti, F. Pantano, A. Rago, A. Siniscalchi, E. Cerchiara, L. Franceschini, L. De Rosa, M. Mariani, S Andriani, L. Cudillo, M. Garcia, M. Cantonetti, S. Mohamed, B. Anaclerico, T. Caravita, F. Stocchi, G. Cimino, S. Gumenyuk, F. Vozella, and G. Avvisati
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ALP ,MM ,Lytic lesions ,Osteoblastic lesions ,Diseases of the musculoskeletal system ,RC925-935 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Introduction: Bone involvement in Multiple Myeloma results from increased osteoclast formation and activity that occurs in proximity to myeloma cells. The role of Alkaline Phosphatse (ALP) in this process and the diagnostic significance of plasma levels in patients with MM are unclear. Aim: To compare plasma ALP levels in patients with MM and solid cancers and metastatic lesions to the bone. Results: In this observational retrospective study we enrolled 901 patients were enrolled: 440 patients (49%) with Multiple Myeloma, 461 (51%) with solid cancers. All 901 patients had bone lesions. Among patients with Multiple Myeloma, ALP values were mainly in the range of normality than those observed in patients with solid cancers and bone lesions. This difference is independent of stage, number and type of bone lesions. Conclusion: This study suggests that plasma ALP has a different clinical significance in MM than in other neoplasms and could be used as a discriminating marker in presence of bone lesions. In particular, lower or normal values, should suggest further investigations such as urinary and serum electrophoresis, associated with bone marrow aspirate in case of the presence of a monoclonal component, in order to confirm or exclude a MM diagnosis.
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- 2021
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3. Comparative evaluation of chitosan-based multifunctional wound dressings: a multistage randomised controlled experimental trial
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D. I. Ushmarov, S. E. Gumenyuk, A. S. Gumenyuk, T. V. Gayvoronskaya, S. Ya. Karablina, А. V. Pomortsev, A. S. Sotnichenko, K. I. Melkonyan, and T. Е. Grigoriev
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aseptic wound ,wound treatment ,wound model ,biopolymers ,wound coating ,wound morphometry ,surgery ,chitosan ,Medicine - Abstract
Background. Wounds of various aetiology are among the most frequent traumatic injuries. A prospective route to improve treatment of this nosology is the development of novel or advancement of the already on-stage dressing materials.Objectives. A comparative experimental assay of novel chitosan-based wound dressings in the healing of soft tissue wounds of different genesis using ultrasound to control biodegradation of the developed dosage form.Methods. Soft tissue wounds were modelled in experimental animals, conventional and lineage male rats, 275 (± 25) g body weight, and male rabbits, 2,900 (± 150) g weight, using a proprietary methodology (Patent on invention RU No. 2703709 dated 23 August, 2018).Two wound dressing samples selected as most promising and applicable in large-volume soft tissue aseptic wounds were tested in the final step of experiment. Ultrasound imaging of the model wound area during the sample material biodegradation was used to control the wound process in more detail. At all steps of experiment, animal models were handled in compliance with GOST 33044-2014 “Principles of Good Laboratory Practice”.Histomorphological assays were carried out with common protocols. Variation statistics was used for the data analysis, including the mean (M) and standard mean error (± m) estimation. The level of statistical significance was p < 0.05.Results. The animal assays and comprehensive evaluation of the obtained data revealed a high healing efficacy of chitosan-based wound coatings. The analyses of wound dressing samples have confirmed their predesigned properties: scaffold stability, capillarity, biodegradability and matrix capacities for the carried drug delivery.Additionally, ultrasound was proved effective to estimate dynamics of the coated wound healing and biopolymer biodegradation processes.Conclusion. The developed chitosan-based wound dressings exhibited efficacy in an experimental model of the soft tissues wound process.The use of ultrasound to study dynamics of the wound process and coating biodegradation provided an adequate congruence between the imaging and tissue histomorphology data, as well as the structure and properties of coating material.
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- 2021
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4. Transit in Regional Economic Development: The Case of the Kaliningrad Exclave
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Ksenia Yu. Voloshenko, Ivan S. Gumenyuk, and Nils Göran Arne Roos
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transit ,transportation system ,regional economy ,situational forecasting and strategizing ,kaliningrad region ,Social Sciences ,Social sciences (General) ,H1-99 - Abstract
The study analyses the role of the transit function in the development of a regional transport system drawing on the example of the Kaliningrad exclave region (Russia). The article studies the role and extent of the impact of changes in the volume and structure of transit operations on the value-added creation in the regional economy. The assessment of the transit function was conducted using analytical software for strategizing and situational forecasting of the socio-economic development of the Kaliningrad region, the analogue of which is the CGE-model. The article describes the results of the regional value-added modelling based on the integrated index of gross regional product (GRP) and the changing volume and structure of transit cargo. The article explores the transit specialisation options for the Kaliningrad region based on different scenarios of its social and economic development and the changes in external factors. The results can be applied to similar studies on assessing the transit potential of a particular territory and developing measures to support the transportation system development in other regions.
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- 2020
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5. Application of multi-layer chitosan-based wound dressings in dentistry
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Alexandr S. Gumenyuk, Denis I. Ushmarov, Sergey E. Gumenyuk, Tatyana V. Gaivoronskaya, Alexandr S. Sotnichenko, Karina I. Melkonyan, Yulia A. Belich, and Timofey E. Grigoriev
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wound dressings ,chitosan ,polymeric materials ,biopolymer ,dentistry ,Medicine - Abstract
Aim. To experimentally evaluate the efficacy of multi-layer chitosan-based wound dressings developed for dental purposes.Materials and Methods. Over the period from 2018 to 2019, an experimental study was conducted to evaluate the efficacy of multi-layer chitosan-based wound dressings developed for dental practice. Two types of dressings (No. 1c and 2c), the central part of which was modified with the introduction of a 10% iodopyron solution, were compared with the widely-used wound dressings Alvostaz (NKF Omega-Dent LLC, Russia) and Gelatamp (Roeko, Germany). The work involved 26 male Chinchilla rabbits, ten months old and weighing 2500 (±50) g. Evaluation of the efficacy of the wound dressings under study was carried by modelling the conditions of both aseptic and purulent-inflammatory processes (a total of 8 series of experiments). In experiments modelling the purulent-inflammatory process, a Ps. aeruginosa bacterial culture at a concentration of 109 CFU/ml was introduced into the alveolar socket after tooth extraction, 3 days before the application of a wound dressing sample. The dressings under study were applied on the wound for the period of 7 days. During the observation postoperative period, the animals were provided with free access to water and food. The sampling of the material for the study was carried out in the operating room on day 7.Results. According to the experimental results, chitosan-based wound dressings (No. 2c in particular) demonstrated high efficacy in experiments on animals (rabbits). The developed wound dressings perform mechanical protection and exhibit fuse effects, as well as are characterized by biodegradability and the ability to deliver medical agents contained therein to the damaged tissue.Conclusion. The proposed chitosan-based wound dressings showed sufficient efficiency on the modelled wound process in the alveolar socket of an extracted tooth. Dressing No. 2c was recognised to be optimal for infected and purulent wounds. This dressing has a dense outer layer, which structure retains frame functions for a long time, thus providing proper drainage of the pathological focus. Dressing No. 1c was established to be promising in cases without inflammatory processes in the extracted tooth socket, where high adhesion to surrounding tissues is initially required for ensuring the tightness and preservation of a blood clot in the wound.
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- 2020
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6. SIMULATION OF WOUND PROCESS IN EXPERIMENTAL SURGERY
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Sergey E. Gumenyuk, Tatiana V. Gaivoronskaya, Alexander S. Gumenyuk, Denis I. Ushmarov, and Diana R. Isyanova
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model ,experiment ,wound ,wound process ,morphology ,Medicine - Abstract
Aim. To study morphological changes in aseptic and purulent soft-tissue wounds using the developed models in animal experiments.Materials and methods. The study was conducted on 70 white non-linear laboratory male rats aged 5 months and weighing 300–350 g. All the investigations were performed in accordance with ethical norms and documents regulating animal experiments. An experimental wound was simulated with the introduction of an implant into soft tissues using a layer-by-layer incision to the required depth. A sterile hydrophilic polymer implant was used for simulating an aseptic wound. A purulent wound was simulated using a porous polymer implant initially saturated with a suspension of a bacterial pathogen at a concentration of 10 5–10 12 microbial cells per 1 ml of suspension. The wounds were sutured layer by layer to form corresponding models. The implants was removed surgically on the 7th day. Statistical analysis of the study results was carried out by Windows 10 operating system using STATISTICA 6.1 (StatSoft Inc., USA) and Excel (Microsoft Offi ce 2010). The hypothesis of normal cumulative distribution in the samples was verifi ed via the Shapiro — Wilk and Kolmogorov — Smirnov tests. The signifi cance level threshold was set to p
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- 2019
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7. Molecular Epidemiological Screening of the Genome of the Strain Coxiella burnetii NL3262 (Netherlands, 2009) Using Formal Order Analysis
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S. N. Shpynov, A. S. Gumenyuk, N. N. Pozdnichenko, and A. A. Skiba
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coxiella burnetii ,q fever ,epidemiology ,genome ,formal order analysis ,matrix of similarity ,map of genes ,average remoteness ,Epistemology. Theory of knowledge ,BD143-237 - Abstract
Background. More than 4,000 cases of acute disease in humans were reported during the mass Q fever outbreak in the Netherlands in 2007–2010. The Coxiella burnetii NL3262 strain was isolated during this outbreak from an aborted placenta of a goat and was studied using means of molecular biology and bioinformation techniques. Goals. Approbation of a new bioinformatics approach – formal order analysis – to study the origin of the strains that caused a massive outbreak of Q fever in the Netherlands using the C. burnetii NL3262 strain. Methodology. New tools of the formal order analysis (FOA) «Map of Genes» and «Matrix of Similarity» (available at http://foarlab. org) were used in this work to study the degree of similarity of the genome (chromosome, plasmid) of this strain with the genomes of other strains of C. burnetii. The nucleotide sequences of the chromosomes of 10 C. burnetii strains and 8 plasmids were loaded from GenBank: www.ncbi.nlm.nih.gov/genome. Results. The map of genes data showed that the chromosome of NL3262 strain significantly distanced from the chromosome of other strains by the characteristic of the average remoteness of nucleotides in the chromosome (g) that ranged from 1.448295 (for Dugway 5J108-111) to 1.448865 1.449640 (for CbRSA331). This may be due to the presence of 106 copies of the «transposase family IS110» gene associated with the growth of virulence, while in the chromosomes of other strains their number ranged only from 1 to 48. The similarity matrix showed that 84.9% of C. burnetii NL3262 chromosome components had complete (100%) homology with chromosome components of strain Z3055. The percentage of similar components ranged from 12.06 to 47.14 for chromosomes of other strains. Plasmids of the pQpH1 type of strains NL3262 and RSA 331 contained 50.0% of components with complete homology. For the same type of plasmids of strain RSA 493 and its clones, the index varied from 28.89 to 29.89%, and for plasmids of other types it was from 5.56 to 6.74%. It is shown that the chromosomes of strains NL3262 and Z3055 have the highest percentage of components with complete homology. However, by the g index, chromosomes of these strains are significantly distanced from each other, due to the large number of copies of IS110 in the chromosome of strain NL3262, which caused the formation of 21 collinear blocks. This led to a change in the properties of the Q fever outbreak strains in the Netherlands and the increase in their epidemiological significance, which caused the largest outbreak in the history of the study of this infection. Conclusions. The results of the study, obtained on the basis of the application of formal order analysis, made it possible to make an assumption about the origin of the strains of Q fever in the Netherlands in 2007–2010. It is shown that the leading reason in the reorganization of the C. burnetii genome is the adaptation of the microorganism to a new ecological niche.
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- 2019
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8. Angiogenesis mechanisms in transplantation of tissue-engineered constructions
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R. Z. Nakokhov, E. A. Gubareva, E. V. Kuevda, A. S. Sotnichenko, I. S. Gumenyuk, G. M. Mogilnaya, and A. H. Kade
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tissue engineering ,angiogenesis ,growth factors ,three-dimensional matrices ,multipotent mesenchymal stromal cells ,Surgery ,RD1-811 - Abstract
There is a number of problems regarding bioengineered structures creation that require further study in the fi eld of regenerative medicine. One of the critical tasks that require solution is the fact that tissue engineered constructions, as a rule, are large, which signifi cantly limits the possibility of diffusion of nutrients and oxygen in them. Thus, the key task of fundamental medicine is to fi nd a technology for restoring the perfusion of the structures created. The article presents a modern overview of the mechanisms of angiogenesis and possible ways of its stimulation during transplantation of tissue engineered constructions.
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- 2018
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9. Modern outlook on morphological criteria of organ and tissue decellularization
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A. S. Sotnichenko, E. A. Gubareva, E. V. Kuevda, I. S. Gumenyuk, I. V. Gilevich, R. Z. Nakokhov, A. A. Slavinskiy, and S. N. Alekseenko
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regenerative medicine ,tissue engineering ,decellularization ,heart. ,Surgery ,RD1-811 - Abstract
A rapidly growing development of tissue engineering promotes the increasing interest in the obtainment of various decellularizedtissues and organs. Minimal quality evaluation criteria of obtained tissue engineered constructions have been previously specified. In the discussionpaper the group of authors considers the morphological methods of matrix evaluation applied by various researchers on the model of heart decellularization. The analysis of modern literature and the authors’ own researches have shown that morphological evaluation of decellularization quality has to be complex and should consist of several stages which include both basic and additional evaluation methods.
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- 2017
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10. Morphological evaluation of the quality of decellularized esophagus in rat
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R. Z. Nakokhov, E. A. Gubareva, E. V. Kuevda, A. S. Sotnichenko, I. S. Gumenyuk, A. Kh. Kade, G. M. Mogilnaya, and D. P. Puzanov
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regenerative medicine ,esophagus ,decellularization ,tissue-engineered construction ,extracellular matrix ,scaffold ,Surgery ,RD1-811 - Abstract
The main aim of our investigation was analysis and optimization of the existing protocols of esophagus decellularization in rats, identification of parameters affecting the quality of decellularization and intactness of the native properties of esophageal extracellular matrix (ECM). Materials and methods. We developed a modified decellularization protocol based on detergent-enzymatic method using sodium deoxycholate and DNAse. Results. Morphological evaluation of the obtained decellularized matrices demonstrated the absence of cells and cell elements while mechanical properties of ECM were preserved. Conclusion. The developed protocol of esophagus decellularization is a potential basis for obtaining of tissue-engineered esophagus scaffold constructions.
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- 2017
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11. COMPARATIVE ANALYSIS OF DENTAL CARIES IN CHILDREN WITH NEUROPSYCHIATRIC DISORDERS AND CONGENITAL CLEFT OF LIP AND PALATE LIVING IN KRASNODAR
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O. V. GULENKO, V. V. VOLOBUEV, A. F. VERAPATVELIAN, A. S. GRACHEVA, A. S. GUMENYUK, and Y. A. VASILEV
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children ,kpu+kp ,kpu ,prevention ,Medicine - Abstract
Examined three groups of children aged 6 to 17 years: the first 96 children with CCLP (congenital cleft of lip and/or palate), the second 112 children with neuropsychiatric disorders (NPD) and the third (control) 86 somatically healthy children. On the basis of the index of KPU + kp and KPU in children with CCLP and in children with NPD high rates of prevalence and intensity of dental caries were found compared with the control group. The highest rates of prevalence of dental caries were found in children with CCLP and intensity of dental caries in children with NPD that is the most prominent in the children with NPD at the age from 6 to 12 years old. In children with CCLP and in children with NPD, the level of oral hygiene has significantly worse values compared to the control, which suggests the possibility of preventing tooth decay through improving oral hygiene of the mouth. The lowest level of oral hygiene was observed in children with CCLP that is mediated by severe congenital pathology.
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- 2017
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12. CLINICAL AND IMMUNOHISTOCHEMICAL STUDIES IN THE DIAGNOSIS OF UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN PATIENTS WITH CHOLELITHIASIS
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S. E. Gumenyuk, R. A. Batchaeva, I. S. Gumenyuk, A. S. Sotnichenko, E. V. Kuevda, E. A. Gubareva, A. V. Gubish, A. G. Grigoriev, and A. M. Manuylov
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недифференцированная дисплазия соединительной ткани ,желчекаменная болезнь ,undifferentiated connective tissue dysplasia ,cholelithiasis ,Medicine - Abstract
There were examined 132 patients in the age of 29-77 years old. Morphological features of abnormal shape or position of gallbladder were detected at 26.9% of patients with undifferentiated connective tissue dysplasia, and this may contribute to the formation of gallstones.
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- 2016
13. MICROBIOLOGICAL CHARACTERIZATION OF THE BACTERIAL FLORA IN PATIENTS WITH PHLEGMON OF THE MAXILLOFACIAL SCOPE
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S. . Gumenyuk, O. A. Kachanova, T. V. Gaivoronskaya, S. E. Gumenyuk, S. K. Shafranova, and V. M. Bensman
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staphylococcus aureus ,антибиотикорезистентность ,гнойные заболеваниями ,antibiotic resistance ,purulent disease ,Medicine - Abstract
The study describes the microbiological state of the patients with phlegmon of the maxillofacial scope. Most of the samples contained Staphylococcus aureus (52,63%). A lot of them produced beta-lactamase and were resistant to penicillin unprotected with inhibitors. Most effective antibiotics, tested during the study, were: azithromycin (90,24%), clindamycin (78,05%) and ciprofloxacin (75,61%).
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- 2016
14. EXPERIENCE OF PERFUSION RECELLULARIZATION OF BIOLOGICAL LUNG SCAFFOLD IN RATS
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E. V. Kuevda, E. A. Gubareva, A. S. Sotnichenko, I. S. Gumenyuk, I. V. Gilevich, I. S. Polyakov, V. A. Porhanov, S. N. Alekseenko, and P. Macchiarini
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decellularization ,recellularization ,rat tissue-engineered lungs ,Surgery ,RD1-811 - Abstract
Aim. The main aim of our research is to evaluate the process of rat lung decellularization and recellularization as the initial step of tissue-engineered organs creation.Materials and methods. Rat lung decellularization was performed by perfusion with detergents and enzymes with concomitant atmospheric air ventilation through the trachea. The quality of decellularization was analyzed with routine histological and immunohistochemical staining techniques, DNA content was determined quantitatively by spectrophotometer. For static and whole organ reseeding as a model of cells’ behavior mesenchymal multipotent stromal cells were used. Recellularization was followed by assessment of the cellular metabolic activity by colorimetric method; cell viability was analyzed by calcein and ethidium homodimer staining. Matrix qualitative evaluation after recellularization was performed using immunohistochemical staining methods.Results. 92% of allogeneic DNA was eliminated after decellularization. Histological staining revealed no residual cells and cell nuclei; preservation of the fibers of extracellular matrix was confirmed by immunohistochemical staining for laminin, elastin, fibronectin, collagen types I and IV before and after decellularization. The scaffold does not exhibit toxic properties after reseeding; cell viability and metabolic activity were proved after cultivation.Conclusion. The experience of rat lung decellularization and recellularization can be the prospective basis for protocols of organ recellularization and tissue engineered lungs creation.
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- 2016
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15. Estimation of the current of sharp purulent inflammatory processes by means of algorithms of the computer analysis of images
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I. S. Gumenyuk, T. V. Gaivoronskaya, S. E. Gumenyuk, O. A. Kachanova, S. K. Shafranova, E. A. Gubareva, A. S. Sotnichenko, and E. V. Kuevda
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компьютерный анализ изображения ,cellprofiler ,гнойные заболевания ,цитологический анализ ,computer image analysis ,purulent disease ,cytological analysis ,Medicine - Abstract
The study describes the automatic algorithm for image analysis based on software Cellprofiler. For the main example of the principal implementation of the analysis process agar culture swabs of Staphylococcus aureus were taken. The proposed algorithms of recognition of microbial elements were verified and showed a significantly higher efficiency compared to the visual method of counting by the laboratory specialist.
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- 2015
16. The Spatial Development of the Rural Settlement of East Prussia: Kaliningrad Region
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Andrey V. Levchenkov and Ivan S. Gumenyuk
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kaliningrad region ,east prussia ,settlement system ,spatial organisation ,Business ,HF5001-6182 ,Economics as a science ,HB71-74 - Abstract
The present system of displacement of the Kaliningrad region’s population results from a complicated historical process, during which the socio-economic, geopolitical and cultural conditions were repeatedly changed in which it was established. An analysis of the changes taking place at that time and now provides the basis for the preparation of forecasts of further transformation of the region’s spatial environment, one of the most important tasks for specialists of the contemporary geographical science. In the publication, the authors examine the key historical stages of the creation of the modern system of displacement of the region’s population and identify the key economic, political and social factors that had an impact on the process at various historical stages of development of East Prussia until 1945 and the contemporary Kaliningrad region. The so-called Nizhnenemanskaya lowland area was chosen as a local example of the transformation processes of the modern part of the Slavsk municipal district (north of the Kaliningrad region). The research results were obtained in the analysis of the cartographic material on the status of the area related to the study of three time stages, 1834-1960, 1914-1939 and 2010-2012. It became possible to compare the cartographic material featuring such a broad time horizon due to the project of the Russian Geographical Society ‘Post-War Changes in the Kaliningrad Region (based on Topographic Maps)’. Based on the performed analysis, at the end of the article the authors formulated the key forward-looking trends in the development of the Kaliningrad region’s rural settlement taking into account the historical features of its foundation as well as the forecast of the social and economic development of the Russian exclave.
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- 2015
17. Structural basis of interaction between mesenchymal stem cells and decellularized rat heart matrix
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A. S. Sotnichenko, A. A. Slavinsky, I. V. Gilevich, E. V. Kuevda, I. S. Gumenyuk, E. A. Gubareva, and P. . Macchiarini
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децеллюляризация ,рецеллюляризация ,сердце ,стволовые клетки ,тканевая инженерия ,decellularization ,recellularization ,heart ,stem cells ,tissue engineering ,Medicine - Abstract
The study presents data about structural interaction between decellularizedrat heart matrix and stem cells used for recellularization. The effect of decellularized scaffold influence on the potential cells ability for differentiation without growth factors was evaluated. Morphological analysis of recellularized rat heart matrix was conducted. Rat heart scaffold influence on the proliferative cells capacity during recellularization process was assessed by immunohistochemical analysis. Cell viability on the scaffold was determined by the colorimetric test with MTT-reagent.
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- 2015
18. AN ASSESSMENT OF THE AVAILABILITY OF TRANSPORT INFRASTRUCTURE OBJECTS IN THE BALTIC REGION
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Tatiana Yu. Kuznetsova and Ivan S. Gumenyuk
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Underdevelopment ,Important conclusion ,Computer science ,Engel's law ,Assessment methods ,Regional science ,General Earth and Planetary Sciences ,Operations management ,Object (computer science) ,Transport system ,General Environmental Science ,Transport infrastructure - Abstract
This article analyses the availability of transport infrastructure objects in the Baltic macroregion. With the help of the cluster and integral assessment methods, the authors differentiate and classify mesoregions of the Baltic macroregion according to the level of development of both individual transport types and the transport system as a whole. The theoretical contribution of the study lies in the revision of the existing integral indices of transport infrastructure object availability, whereas the practical contribution of the study relates to the possibility to apply the results obtained in developing and adjusting regional and industry-specific transport development programmes. An important conclusion of the study is the practical confirmation of the significant underdevelopment of the regions of North-West Russia (within the Baltic region) as to the availability of transport infrastructure objects in comparison to most mesoregions of the Baltic macroregion. KEYWORDS: Baltic region, transport infrastructure, Engel coefficient, the coefficient of transport infrastructure availability. DOI: http://dx.doi.org/ 10.15181/rfds.v12i1.690
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- 2021
19. Innovative development of Russian coastal regions: north–south divergence
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Andrey S. Mikhaylov, Ivan S. Gumenyuk, Dmitry V. Hvaley, and Vasilisa Valer'evna Gorochnaya
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0106 biological sciences ,innovation geography ,History ,Stadtgeographie ,Sociology and Political Science ,Geography, Planning and Development ,Lebensstandard ,0211 other engineering and technologies ,02 engineering and technology ,coastal region ,lcsh:Regional economics. Space in economics ,digitalization ,01 natural sciences ,Russia ,innovation potential ,Divergence ,urban geography ,innovation capital ,coastalisation ,urban agglomeration ,innovation space ,Lebensqualität ,Innovationspotential ,Sozialwissenschaften, Soziologie ,Modellvergleich ,Innovationspolitik ,021107 urban & regional planning ,Wirtschafts- und Sozialgeographie ,economic growth ,lcsh:HT388 ,Geography ,model comparison ,ddc:300 ,Russland ,General Economics, Econometrics and Finance ,Digitalisierung ,Cultural Studies ,geographische Faktoren ,Paleontology ,Küstenregion ,Humankapital ,human capital ,Social sciences, sociology, anthropology ,standard of living ,regionale Entwicklung ,Wirtschaftswachstum ,010604 marine biology & hydrobiology ,regional development ,Economic and Social Geography ,quality of life ,innovation policy ,geographical factors ,Social Sciences (miscellaneous) - Abstract
Coastal regions are territorial social systems whose socio-economic and innovative development is strongly influenced by the factor of coastalisation. The effect of movement to the sea determines the dynamics of settlement systems as well as their economic and infrastructure development. This holds for transport, logistics, information and communications, industrial, and other infrastructure. Coastal regions are so diverse that it is impossible to construct a development model that will fit all of them. One can speak only of general trends. This study focuses on identifying differences between the innovation systems of northern and southern coastal regions within the same country. The geographical scope of the study is four Russian coastal territories: Murmansk and Arkhangelsk in the Baltic Sea region and Rostov and Krasnodar in the Azov-Black Sea region. Methodologically, this study carries out a comparative assessment of heterogeneity of innovative development at municipal and interregional levels, using four groups of indicators: human capital, economic growth and clustering, innovation and digitalisation, and quality and standards of living. All these components are vital for regional innovative development. A statistical assessment is supplemented by a qualitative analysis of spatial patterns of innovation capital accumulation; the agglomeration factor is taken into account. It is shown that northern and southern coastal regions perform very differently on innovative development, the latter doing better than the former. Three main models of innovation generation, implementation, and accumulation of coastal regions are described. Each is associated with a different way to benefit from proximity to the sea. These are maritime activities, maritime transport, and the economic use of recreational, natural and climatic resources.
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- 2020
20. Experience of the application of antiseptics for the treatment of biological matrixes of rat lung
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A. A. Basov, S. N. Chvalun, T. E. Grigoriev, E. A. Gubareva, S. S. Dzhimak, O. A. Kachanova, E. V. Kuevda, S. V. Krasheninnikov, and I. S. Gumenyuk
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Extracellular matrix ,Multidisciplinary ,Decellularization ,Lung ,medicine.anatomical_structure ,Chemistry ,Chlorhexidine ,medicine ,Biomechanical strength ,Octenisept ,Biomedical engineering ,medicine.drug - Abstract
In order to select the optimal method for disinfecting the scaffolds prior to decellularization using morphological methods (studying the biomechanical strength of extracellular matrix fibers) and analyzing chemiluminescence in rats, the effect of octenisept and chlorhexidine was studied at different concentrations on the biological matrices of the lungs before and after decellularization. Chlorhexidine at a dilution of 1:10 possessed the least damaging properties for the matrix and most contributed to the decontamination of the cages for further storage and experimental studies.
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- 2019
21. About Similarity Measures of Components Arrangement of Naturally Ordered Data Arrays
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Alexander S. Gumenyuk, Nikolay Pozdnichenko, Artemiy Skiba, and Stanislav N. Shpynov
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Similarity (network science) ,Artificial Intelligence ,Computer Networks and Communications ,Control and Systems Engineering ,business.industry ,Applied Mathematics ,Pattern recognition ,Artificial intelligence ,business ,Mathematics - Abstract
At present, adequate mathematical tools are not used to analyze the arrangement of components in arrays of naturally ordered data of a different nature, including words or letters in texts, notes in musical compositions, symbols in sign sequences, monitoring data, numbers representing ordered measurement results, components in genetic texts. Therefore, it is difficult or impossible to measure and compare the order of messages allocated in long information chains. The main approaches for comparing symbol sequences are using probabilistic models and statistical tools, pairwise and multiple alignment, which makes it possible to determine the degree of similarity of sequences using edit distance measures. The application of pseudospectral and fractal representation of symbolic sequences is somewhat exotic. "The curse of a priori unconscious knowledge" of the obvious orderliness of the sequence should be especially noticed, as it is widespread in mathematical linguistics, bioinformatics (mathematical biology), and other similar fields of science. The noted approaches almost do not pay attention to the study and detection of the patterns of the specific arrangement of all symbols, words, and components of data sets that constitute a separate sequence. The object of study in our works is a specifically organized numerical tuple – the arrangement of components (order) in symbolic or numerical sequence. The intervals between the closest identical components of the order are used as the basis for the quantitative representation of the chain arrangement. Multiplying all the intervals or summing their logarithms allows one to get numbers that uniquely reflect the arrangement of components in a particular sequence. These numbers, allow us to obtain a whole set of normalized characteristics of the order, among which the geometric mean interval and its logarithm. Such characteristics surprisingly accurately reflect the arrangement of the components in the symbolic sequences. In this paper, we present an approach for quantitative comparing the arrangement of arrays of naturally ordered data (information chains) of an arbitrary nature. The measures of similarity/distinction and procedure of comparison of the chain order, based on the selection of a list of equal and similar by the order characteristics of the subsequences (components), are proposed. Rank distributions are used for faster selection of a list of matching components. The paper presents a toolkit for comparing the order of information chains and demonstrates some of its applications for studying the structure of nucleotide sequences.
- Published
- 2019
22. Experience in Training Resident Doctors of Surgical Specialties Using an Experimental Model of Soft Tissue Wounds
- Author
-
S. E. Gumenyuk, A. S. Gumenyuk, and D. I. Ushmarov
- Subjects
medicine.medical_specialty ,integumentary system ,Experimental model ,business.industry ,education ,medicine ,Soft tissue ,Medical physics ,business - Abstract
The problem of treating wounds of various origins remains one of the most urgent. Working with a wound defect is one of the main components of the healing process, due to the need to find the most effective methods for treating wounds and caring for them.Due to the COVID-19 pandemic, limited access of students to health care facilities makes it impossible or difficult to teach local wound healing skills in real patients. Under these conditions, one of the options for solving this problem is the use of experimental biological models for practical training.
- Published
- 2021
23. Transport connectivity as a factor in overcoming challenges of the periphery: the case of rural areas in the Kaliningrad region
- Author
-
Ivan S. Gumenyuk and Lidia G. Gumenyuk
- Subjects
Cultural Studies ,socioeconomic development ,History ,Sociology and Political Science ,Geography, Planning and Development ,Raumplanung und Regionalforschung ,rural area ,ländlicher Raum ,Russia ,Ballungsgebiet ,periphery ,Verkehrserschließung ,ddc:710 ,Lebensqualität ,agglomeration area ,Landscaping and area planning ,Städtebau, Raumplanung, Landschaftsgestaltung ,sozioökonomische Entwicklung ,Area Development Planning, Regional Research ,transport connectivity ,settlement system ,Kaliningrad agglomeration ,local centres ,quality of life ,transportation infrastructure development ,Russland ,Peripherie ,General Economics, Econometrics and Finance ,Social Sciences (miscellaneous) - Abstract
Quality of life in rural areas is increasingly dependent on transport links to nearest towns and regional centres. In this article, we examine transport connectivity between villages and towns in the Kaliningrad region. We use the travel time access parameter to investigate the influence of transport connectivity on the population size and the prospects of socio-economic development in rural areas with different transport and geographical situations. Although the overall transport connectivity is high in the region, up to 10 per cent of villages score low on this parameter. We conclude that the demographic saturation of the Kaliningrad agglomeration has not been completed. Moreover, the smallness of the local consumer market impedes the formation of subregional centres in the eastern part of the region. The most alarming trend is the incipient concentration of population in peripheral border areas.
- Published
- 2021
24. Does the coastal location of municipalities influence their innovation development?
- Author
-
Angelina P. Plotnikova, Ivan S. Gumenyuk, Andrey Mikhaylov, Anna Mikhaylova, and Vasilisa Gorochnaya
- Subjects
education.field_of_study ,Geography, Planning and Development ,Population ,Geology ,Sample (statistics) ,Environmental Science (miscellaneous) ,Human capital ,Knowledge production ,Business environment ,Geography ,Coastal zone ,General Earth and Planetary Sciences ,Economic geography ,Location ,education ,Innovation development - Abstract
The coastal regions are increasingly in the focus of contemporary academic research as economically favorable territories with high innovative potential. The coastalization factor gets individual attention, the influence of which is registered in various countries of the world as a tendency of the population and economic activity to concentrate in the coastal zone. However, there is significant heterogeneity between the coastal areas, due to natural and climatic features and affecting their economic development. This paper focuses on assessing the differences in the readiness of the coastal regions of the European part of Russia to the innovation economy, taking into account their geographical location (northern, northwestern, southern). The study is conducted at the level of municipalities across 6 regions of Russia: Murmansk, Arkhangelsk, Leningrad, Kaliningrad, Rostov regions, and Krasnodar Krai. The research methodology included an assessment of 4 most important components of an innovative economy: human capital, business environment, knowledge production, and technological equipment. The results of the study showed a high degree of spatial divergence in terms of the level of readiness for the development of an innovative economy both between the regions of the sample and within them in the inter-municipal context. It is revealed that the concentration of innovative potential within the coastal region is largely the result of the cross-influence of the agglomeration and the coastalization factors. In the case of their complementary influence on coastal municipalities, the latter are characterized by a relatively higher level of readiness for the development of an innovative economy than inland ones. This is true for both the northern, northwestern, and southern coastal regions of the European part of Russia.
- Published
- 2021
25. PHYSICAL TRAINING IN REHABILITATION OF 10-13 YEARS OLD CHILDREN WITH FRACTURES OF BONES OF THE LOWER THIRD OF FOREARM
- Author
-
S, Gumenyuk, I, Hrubar, Y, Hrubar, N, Hrabyk, and S, Saprun
- Subjects
Forearm ,Fractures, Bone ,Adolescent ,Humans ,Child ,Bone and Bones - Abstract
The research is devoted to the problem of rehabilitation of 10-13 years old children with the fractures of bones of the lower third of forearm by means of physical training. The purpose of the work is to identify factors of injuries emergence in children, creating and checking efficiency of the physical rehabilitation program on the example of the fractures of bones of the lower third of forearm. The causes of children's school injuries have been analyzed and the following are established: organizational-methodical, sanitary-hygienic and psychophysiological. The methods of evaluating the efficiency of physical rehabilitation of children with the fractures of bones of the lower third of forearm have been developed. There are three periods of physical rehabilitation, which conditionally are divided into: immobilizational, functional and training. The physical rehabilitation program for children with the fractures of bones of the lower third of forearm, the technology of conducting kinesitherapy in the process of physical rehabilitation of children with the fractures of bones of the lower third of forearm and complexes of exercises oriented on a gradual increase of amplitude of movements of radio-carpal joint and prevention of disorders of functional state of the injured segment muscles have been developed and implemented. The physical rehabilitation program for children with the fractures of bones of the lower third of forearm is based on pedagogical principles, provides appropriate forms (hygienic gymnastic, independent study), methods (gymnastic, gaming, sporting) and ensures adequate pedagogical conditions. It have been produced and recommended preventive measures of organizational (during lessons and after school time), methodical, sanitary-hygienic and educational character for the realization at schools.
- Published
- 2020
26. Morphological Evaluation of the Tissue Reaction to Subcutaneous Implantation of Decellularized Matrices
- Author
-
E. A. Gubareva, I. S. Gumenyuk, R. Z. Nakokhov, E. V. Kuevda, and A. S. Sotnichenko
- Subjects
Male ,0301 basic medicine ,Pathology ,medicine.medical_specialty ,Molecular composition ,T-Lymphocytes ,Lymphocyte ,Diaphragm ,Receptors, Cell Surface ,02 engineering and technology ,General Biochemistry, Genetics and Molecular Biology ,03 medical and health sciences ,Tissue engineering ,Antigen ,Antigens, CD ,medicine ,Animals ,Transplantation, Homologous ,Macrophage ,Lectins, C-Type ,Rats, Wistar ,Lung ,Skin ,B-Lymphocytes ,Deoxyribonucleases ,Decellularization ,Tissue Engineering ,Tissue Scaffolds ,Chemistry ,Macrophages ,Heart ,General Medicine ,021001 nanoscience & nanotechnology ,Extracellular Matrix ,Rats ,Mannose-Binding Lectins ,030104 developmental biology ,medicine.anatomical_structure ,Morphological analysis ,Subcutaneous implantation ,0210 nano-technology ,Biomarkers ,Mannose Receptor ,Deoxycholic Acid - Abstract
Based on the data of morphological analysis, we performed histological evaluation of rat tissue reaction to subcutaneous implantation of decellularized matrices of intrathoracic organs and tissues. Cell composition of the inflammatory infiltrate was analyzed, and the dynamics of macrophage and T and B lymphocyte content was assessed on days 7 and 14 of the experiment. It was found that the reaction to implantation depended not only on the quality of decellularization and efficiency of removal of antigen molecules, but also on the original histological structure and quality of preimplantation processing of the transplant.
- Published
- 2018
27. GENOMOSYSTEMATICS OF RICKETTSIAE
- Author
-
Shpynov Sn, A.A. Skiba, A. S. Gumenyuk, and N.N. Pozdnichenko
- Subjects
0301 basic medicine ,030106 microbiology ,Immunology ,Infectious and parasitic diseases ,RC109-216 ,rickettsioses ,virulence ,03 medical and health sciences ,030104 developmental biology ,Infectious Diseases ,rickettsiae ,Immunology and Allergy ,epidemiology ,ecology ,systematics ,genome ,Mathematics ,formal order analysis ,genomosystematics - Abstract
The definition of the term genome was given by the German botanist G. Winkler almost one hundred years ago in 1920. A genome definition for bacterial (rickettsia) with a single chromosome was recently presented from the perspective of information theory, biology and bioinformatics as the information chain of nucleotides. The systematics of rickettsiae (obligate intracellular microorganisms) is based on a limited number of phenotypic characters. Classifications built on the analysis of genes, fragments of genomes and their concatenations cause discussion. Application of the Formal Order Analysis (FOA, http://foarlab.org) in the study of complete genomes allowed to submit the systematics of representatives of the family Rickettsiaceae. This approach confirmed the existence of typhus group (TG), spotted fever group (SFG), and an «ancestral» group within the genus Rickettsia, and allowed the isolation of the Rickettsia felis group within this genus, located between the «ancestral» group and the SFG and the R. akari group on the border between the SFG group and the genus Orientia. The development of the tools of FOA — «Map of Genes» and «Matrix of Similarity» — helped to conduct an in-depth study of the complete genomes of rickettsia, taking into account the characteristics of their genes and noncoding sequences. Application of these instruments, with the help of the obtained classification, confirmed the notion of ecological features of rickettsia, the structure of nosological forms and the epidemiological patterns of rickettsiosis, and made it possible to assess the virulence of the strains of the two most pathogenic species of rickettsia, R. prowazekii and R. rickettsia. In this work, for the first time, a holistic, consistent and multidimensional observation of a set of closely related bacteria (a family of bacteria) and the manifestations associated with them was carried out. The basis of the developed and herein described systematic approach to the study of bacteria is a new mathematical model — the arrangement of nucleotides in a complete genome and its sensitive unambiguous numerical characteristics. A new methodological approach named genomosystematics and based on mathematical modeling of complete genomes of rickettsiae (bacteria) using FOA. Classification of rickettsiae and rickettsioses obtained with the help of this approach corresponds to ecological, epidemiological and etiological principles. Application of the genomosystematics can serve the goals and objectives of preventive medicine. The publication completes a series of scientific works presenting the methodology of an integrated approach based on the application of mathematical analysis tools in the study of objects and laws of natural science disciplines of biological and medical profile.
- Published
- 2018
28. Map of genes - new tool for representation of a single-chromosome genomes and their components
- Author
-
Alexander S. Gumenyuk, N.F. Gamaleya Frcem, Nikolai N. Pozdnichenko, and Stanislav N. Shpynov
- Subjects
Chromosome (genetic algorithm) ,Computer Networks and Communications ,Representation (systemics) ,Computational biology ,Biology ,Gene ,Genome ,Computer Science Applications ,Information Systems - Published
- 2018
29. The Effectiveness of Preimplantation Recellularization of Acellular Rat-Esophagus Matrices Using GFP-Positive Cells
- Author
-
R. Z. Nakokhov, I. S. Gumenyuk, E. V. Kuevda, A. S. Sotnichenko, D. P. Puzanov, and E. A. Gubareva
- Subjects
0301 basic medicine ,education.field_of_study ,Scaffold ,Decellularization ,Cell growth ,Population ,Cell Biology ,Biology ,Rat Esophagus ,Green fluorescent protein ,Cell biology ,Transplantation ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,In vivo ,030220 oncology & carcinogenesis ,education - Abstract
The use of recellularized matrices allows obtaining tissue-engineered structures that largely reproduce the morphofunctional features of native organs and tissues. Doubts as to the advisability of preimplantation recellularization of the scaffold, which are associated with the death of prepopulation cells on the scaffold in vivo, require studying the behavior of cells on plastic and biological implants after recellularization. Rat esophagus that had undergone detergent-enzymatic decellularization was repopulated with GFP-positive cells intensely fluorescing in the green spectrum, which allowed us to trace the status of the initial cell population during cultivation on plastic and after transplantation, determine the viability and metabolic activity of cells, and conduct fluorescent detection of the cells on the scaffold before and after implantation. There were no data on the apparent cell proliferation on the matrix; however, there were indirect indications of metabolic activity and GFP synthesis by the cells that populated the scaffold before implantation.
- Published
- 2018
30. Serial and complex description of the order of components in data sets
- Author
-
Alexander S. Gumenyuk
- Subjects
Computer Networks and Communications ,Computer science ,Order (business) ,Algorithm ,Computer Science Applications ,Information Systems - Published
- 2018
31. National and international passenger transport accessibility of the Kaliningrad region of the Russian Federation: modern configuration and development plans
- Author
-
Ivan S. Gumenyuk
- Subjects
Passenger transport ,Regional science ,Russian federation ,Business ,Transport system - Abstract
National and international passenger transport accessibility of the Kaliningrad region of the Russian Federation: modern configuration and development plans
- Published
- 2018
32. Human Development Index as a Tool to Assess Social Development in the Baltic States
- Author
-
Ivan S. Gumenyuk
- Subjects
Cultural Studies ,Baltic States ,index ,History ,Index (economics) ,Sociology and Political Science ,national social development ,Geography, Planning and Development ,0211 other engineering and technologies ,Baltic region ,Soziologie von Gesamtgesellschaften ,02 engineering and technology ,Entwicklungsstrategie ,lcsh:Regional economics. Space in economics ,development strategy ,Sociology & anthropology ,Macrosociology, Analysis of Whole Societies ,soziale Entwicklung ,Russia ,Quality of life ,0502 economics and business ,Human Development Index ,050207 economics ,Socioeconomics ,Lebensqualität ,05 social sciences ,Social change ,social change ,021107 urban & regional planning ,lcsh:HT388 ,Baltikum ,Geography ,quality of life ,Soziologie, Anthropologie ,comparison ,human development index ,Russland ,Vergleich ,ddc:301 ,General Economics, Econometrics and Finance ,Social Sciences (miscellaneous) - Abstract
Reinvigorating Russia’s development strategy requires a comparison between the social development of the Russian Federation and other Baltic region states, some of which are world leaders in terms of living standards. The most popular tools for country comparison are composite indices that take into account various components affecting the quality of life. This article analyses the current level and changes in the social development of the Baltic States in 1990—2016. The analysis is based on the values of human development index. Having distinct advantages and disadvantages, this index remains to be the most popular and influential tool for assessing a country’s social development. A statistical analysis carried out with the use of HDI values makes it possible to divide the Baltic States into three groups according to their current development level and advancement trajectories. The greatest gap in progress was observed in 2000. Later, it narrowed as the social advancement of the third group — Lithuania, Latvia, and Russia — accelerated. The nature of the Baltic States’ social improvement in 2015—2016 suggests that a decrease in social development rates will be observed in the coming years across the region, and the gap between the countries will increase.
- Published
- 2017
33. COMPARATIVE ANALYSIS OF DENTAL CARIES IN CHILDREN WITH NEUROPSYCHIATRIC DISORDERS AND CONGENITAL CLEFT OF LIP AND PALATE LIVING IN KRASNODAR
- Author
-
V. V. Volobuev, A. S. Gracheva, A. F. Verapatvelian, Y. A. Vasilev, A. S. Gumenyuk, and O. V. Gulenko
- Subjects
Orthodontics ,stomatognathic diseases ,kpu ,children ,prevention ,business.industry ,kpu+kp ,Dentistry ,Medicine ,Congenital cleft ,business - Abstract
Examined three groups of children aged 6 to 17 years: the first 96 children with CCLP (congenital cleft of lip and/or palate), the second 112 children with neuropsychiatric disorders (NPD) and the third (control) 86 somatically healthy children. On the basis of the index of KPU + kp and KPU in children with CCLP and in children with NPD high rates of prevalence and intensity of dental caries were found compared with the control group. The highest rates of prevalence of dental caries were found in children with CCLP and intensity of dental caries in children with NPD that is the most prominent in the children with NPD at the age from 6 to 12 years old. In children with CCLP and in children with NPD, the level of oral hygiene has significantly worse values compared to the control, which suggests the possibility of preventing tooth decay through improving oral hygiene of the mouth. The lowest level of oral hygiene was observed in children with CCLP that is mediated by severe congenital pathology.
- Published
- 2017
34. Morphological evaluation of the quality of decellularized esophagus in rat
- Author
-
E. V. Kuevda, A. Kh. Kade, A. S. Sotnichenko, I. S. Gumenyuk, R. Z. Nakokhov, D. P. Puzanov, G. M. Mogilnaya, and E. A. Gubareva
- Subjects
Scaffold ,RD1-811 ,extracellular matrix ,regenerative medicine ,02 engineering and technology ,scaffold ,Regenerative medicine ,Extracellular matrix ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Immunology and Allergy ,Esophagus ,Sodium Deoxycholate ,esophagus ,Transplantation ,Decellularization ,Chemistry ,Anatomy ,021001 nanoscience & nanotechnology ,tissue-engineered construction ,medicine.anatomical_structure ,030211 gastroenterology & hepatology ,decellularization ,Surgery ,0210 nano-technology ,Biomedical engineering - Abstract
The main aim of our investigation was analysis and optimization of the existing protocols of esophagus decellularization in rats, identification of parameters affecting the quality of decellularization and intactness of the native properties of esophageal extracellular matrix (ECM). Materials and methods. We developed a modified decellularization protocol based on detergent-enzymatic method using sodium deoxycholate and DNAse. Results. Morphological evaluation of the obtained decellularized matrices demonstrated the absence of cells and cell elements while mechanical properties of ECM were preserved. Conclusion. The developed protocol of esophagus decellularization is a potential basis for obtaining of tissue-engineered esophagus scaffold constructions.
- Published
- 2017
35. Scenarios of increasing the economic efficiency of the Kaliningrad regional transport system
- Author
-
Ivan S. Gumenyuk and Ksenia Yu. Voloshenko
- Subjects
Cultural Studies ,National Economy ,History ,Volkswirtschaftstheorie ,Sociology and Political Science ,Economics ,Ostseeraum ,Geography, Planning and Development ,Raumplanung und Regionalforschung ,Baltic region ,Russia ,Szenario ,Güterverkehr ,surplus value ,ddc:330 ,Region ,transport system ,ddc:710 ,Landscaping and area planning ,Städtebau, Raumplanung, Landschaftsgestaltung ,freight traffic ,Area Development Planning, Regional Research ,Wirtschaft ,Verkehrssystem ,Mehrwert ,simulation ,regional economy ,Kaliningrad region ,value added ,simulation modelling ,scenario ,economic efficiency ,Wirtschaftlichkeit ,model construction ,Russland ,Modellentwicklung ,General Economics, Econometrics and Finance ,Social Sciences (miscellaneous) - Abstract
The development of the considerable transport and logistics potential of the Kaliningrad region is hampered by several factors. This problem, to which we will refer to as a transport deadlock effect, translates into the limited contribution of transport to the regional economy. Particularly, it manifests itself at the level of regional gross value added, where the contribution of transport is much smaller than one might expect given the significant role the industry plays in the economy of the region. In this study, we examine major ways of increasing the economic efficiency of the regional transport system from the value added perspective. We posit that the structure of cargo handled and the redistribution of value added in favour of regional actors have the dominant influence on economic efficiency. Using our own simulation model and the earlier developed system of transport tariffs and value added calculation for the Kaliningrad region, we produce scenarios and consider changes in value added in the case of selected cargoes carrying intermediate, investment, and consumer goods (as defined in the International Classification for Broad Economic Categories ICT BEC-4). Our calculations show that higher value added and greater economic efficiency of a regional transport system are associated with re-orientation towards investment and consumer goods. The most visible effect is associated with rail and road transport. As to sea transport, the decisive role is played by an increase in the physical volume of cargo handled. The results of this study and its modelling tools can be applied in the analysis of the current situation and in the assessment of the efficiency of transport systems in other regions. Another possible application is the identification of growth conditions for an industry, particularly, when developing projects and proposals for increasing the efficiency of transport services.
- Published
- 2019
36. Bone marrow and adipose-derived rat mesenchymal stem cells for recellularization of biological matrices
- Author
-
Ramazan Nakohov, E. A. Gubareva, Dmitry Petrovich Puzanov, Еlena Kuevda, and I. S. Gumenyuk
- Subjects
medicine.anatomical_structure ,Chemistry ,Mesenchymal stem cell ,medicine ,Adipose tissue ,General Medicine ,Bone marrow ,Cell biology - Published
- 2019
37. Local border traffic as an efficient tool for developing cross-border cooperation
- Author
-
Tatyana Yu. Kuznetsova, Ivan S. Gumenyuk, and Lidiya G. Osmolovskaya
- Subjects
History ,Republic of Belarus ,010504 meteorology & atmospheric sciences ,Sociology and Political Science ,Raumplanung und Regionalforschung ,Belorussia ,Geography, Planning and Development ,social relations ,lcsh:Regional economics. Space in economics ,Public administration ,01 natural sciences ,Sociology & anthropology ,Russia ,Russian Federation ,Allgemeine Soziologie, Makrosoziologie, spezielle Theorien und Schulen, Entwicklung und Geschichte der Soziologie ,050602 political science & public administration ,Regional science ,sozioökonomische Lage ,Sociology ,ddc:710 ,Norwegen ,Städtebau, Raumplanung, Landschaftsgestaltung ,dialogue ,cross-border traffic ,Norway ,Area Development Planning, Regional Research ,05 social sciences ,grenzüberschreitende Zusammenarbeit ,socioeconomic position ,lcsh:HT388 ,0506 political science ,Weißrussland ,foreign policy ,Russland ,ddc:301 ,internationale Beziehungen, Entwicklungspolitik ,General Economics, Econometrics and Finance ,contact ,Cultural Studies ,local border traffic ,Internationale Beziehungen ,soziale Beziehungen ,cross-border cooperation ,European Union ,General Sociology, Basic Research, General Concepts and History of Sociology, Sociological Theories ,Außenpolitik ,0105 earth and related environmental sciences ,Landscaping and area planning ,Grenzgebiet ,Kontakt ,Dialog ,International Relations, International Politics, Foreign Affairs, Development Policy ,Cross-border cooperation ,Soziologie, Anthropologie ,border region ,LOCAL BORDER TRAFFIC,CROSSBORDER TRAFFIC,EUROPEAN UNION,RUSSIAN FEDERATION,REPUBLIC OF BELARUS ,International relations ,EU ,Social Sciences (miscellaneous) ,ddc:327 - Abstract
Local border traffic (LBT) is a tool for cooperation between the EU member states and neighbouring countries. It emerged as a measure to mitigate the barrier effect of the EU’s external border. In 2006, the European Parliament authorised the EU member states to conclude bilateral agreements on a simplified border crossing regime in border areas. This article analyses local border traffic as a cross-border cooperation tool. The territory described in the study includes the external borders of the EU (and Norway) with the Russian Federation and the Republic of Belarus. The article will be of interest to specialists in international and, particularly, in cross-border cooperation. The authors analyse the mechanism of local border traffic and identify possible trends based on the general socioeconomic situation and foreign policy background in Russia, Belarus, and the EU (Norway). The article employs the cartographic method to enhance the visual component of the study. It is concluded that the LBT mechanism is effective and it has a positive effect on the development of border contacts between countries. There is a need to continue the dialogue between Russia, Belarus and the EU countries on both expanding the geographical scope of the LBT mechanism and ensuring its qualitative development.
- Published
- 2016
38. THE ITSENKO–CUSHING SYNDROME CAUSED BY THE UNCONTROLLED USE OF TOPICAL GLUCOCORTICOSTEROIDS
- Author
-
M. Shavilova, M. Tlish, N. Komissarova, M. Gluzmin, E. Erokhina, and S. Gumenyuk
- Subjects
medicine.medical_specialty ,business.industry ,Medicine ,business ,Dermatology ,Itsenko-Cushing syndrome - Published
- 2018
39. Development of non -human primates heart decellularization method. Morphological evaluation of matrix
- Author
-
Ramazan Nakohov, Еlena Kuevda, I. S. Gumenyuk, Sergey Orlov, Alexander Sotnichenko, and E. A. Gubareva
- Subjects
Matrix (mathematics) ,Decellularization ,Chemistry ,General Medicine ,Biomedical engineering - Published
- 2018
40. To question of quantitative evaluation of α-SMA expression in a denomyosis
- Author
-
Anna Simovonik, E. A. Gubareva, Alexander Sotnichenko, Galina Mogilnaja, I. S. Gumenyuk, and Еlena Kuevda
- Subjects
Expression (architecture) ,General Medicine ,Biology ,SMA ,Cell biology - Published
- 2018
41. Evaluation of the free radicals production rate in tissue -engineered constructions using EPR -srectroscopy
- Author
-
Oksana Lyasota, Alexander Sotnichenko, I. M. Bykov, I. S. Gumenyuk, Еlena Kuevda, S. S. Dzhimak, Sergey Bolotin, and E. A. Gubareva
- Subjects
Tissue engineered ,law ,Chemistry ,Radical ,General Medicine ,Electron paramagnetic resonance ,Photochemistry ,law.invention ,Production rate - Published
- 2018
42. Measurement of the lifetime of tau-lepton
- Author
-
U. Mjoernmark, Edoardo Castelli, F. Pierre, P. Allen, G. W. Van Apeldoorn, R. J. Apsimon, L. Ventura, V. Ruhlmann, Roland Horisberger, L. Bugge, D. Z. Toet, G. Hamel de Monchenault, Andrey Korytov, G. Ekspong, Itzhak Roditi, Gueorgui Chelkov, Pierre Juillot, M. De Beer, M. Bonesini, Y. Sacquin, Josef Strauss, M.A. Lopez Aguera, Francesca Romana Cavallo, Hans Muller, B. Koene, J.A.M.A. Buytaert, W. Venus, L. Di Ciaccio, Jan Krolikowski, N. N. Khovanski, Mitchell Wayne, M. S. Bilenky, G. Tristam, L.J. Carroll, W. Bartl, R. Pain, P. N. Bogolubov, M. J. Bates, J. A. Valls Ferrer, Giovanni Darbo, Christine Kourkoumelis, P. Siegrist, V. V. Lapin, N. Crosland, S. Simonetti, M. Begalli, E. Dahl-Jensen, Paolo Morettini, J. G. Loken, C. De Clercq, Klaus Hamacher, J. P. Laugier, Natale Demaria, R. Lucock, M. Richardson, G. Meola, Toralf Bernhard Skaali, M. Boratav, D. Gamba, P. Beilliere, M. Battaglia, T. Bolognese, W. J. Murray, R. Strub, J-C. Marin, Spyros Tzamarias, G. Cosme, A. Perrotta, G. Borisov, George Kalkanis, P. B. Renton, G. Voulgaris, M. Pimenta, B. A. Khomenko, M. Baubillier, V. Canale, S. Gumenyuk, R. A. Brenner, Stavros Maltezos, M. Bonapart, O. Barring, Y. Dufour, P. D. Dauncey, Sandor Czellar, D. C. Fries, Patrick Jarry, S. J. Alvsvaag, C. Vander Velde, N. De Groot, G. Rinaudo, G. Sette, A. Elliot Peisert, A. Stocchi, Francesco Navarria, J. Zúñiga, P. Astier, W. Bonivento, P. Weilhammer, A. M. Zaitsev, Alexander Vodopyanov, F. Bianchi, G. Vegni, N. Brummer, J. Bjarne, P. O. Hulth, T. Tabarelli, P. Van Dam, M. Davenport, G. Polok, A. Ruiz, Winfried Mitaroff, E. Lieb, P. Antilogus, C. Lambropoulos, Ugo Amaldi, W. De Boer, E. Zevgolatakos, G. Matthiae, Marta Calvi, P. Delpierre, I. Herbst, M. Matveev, R. Mc Nulty, I. Lippi, W. Kucewicz, E. K. Johansson, J. Pyyhtia, Geoffrey Smith, D. Johnson, Louis Lyons, W. Klempt, Renato Turchetta, H. De Boeck, S. Tavernier, G. Wormser, E. Daubie, G. E. Theodosiou, Mogens Dam, D. Fassouliotis, Ariella Cattai, F. Couchot, M. Kopf, M. Tyndel, S. C. Blyth, O. Pingot, G. Wilkinson, M.D.M. De Fez Laso, Juan Fuster, Jacques Lemonne, J. Sanchez, C. Bosio, E.N. Tsyganov, J. H. Wickens, Jose Luis Contreras, T. Kreuzberger, J. Derkaoui, S. Braibant, S. Dagoret, F. Stichelbaut, D. Zavrtanik, A. Tilquin, S. O. Holmgren, L. S. Vertogradov, J. Maillard, M. T. Trainor, P. Vaz, R. Sosnowski, O. Ullaland, Leif J. Jönsson, G. Myatt, F. Adami, V. G. Timofeev, A. G. Frodesen, Pawel Jalocha, Barry King, G. Smadja, L. Mathis, D. Husson, Ugo Gasparini, A. Pullia, J.M. Gago, D. Bertrand, J. Timmermans, I. A. Tyapkin, B.D. Hyams, T. S. Spassoff, Torsten Paul Ake Åkesson, Demetrios Loukas, R. Keranen, Philippe Charpentier, Francisco Matorras, N. Yamdagni, U. Trevisan, H. Furstenau, R. Frühwirth, L. O. Eek, R. C. Shellard, Josef Hrubec, A. M. Segar, A. G. Olshevski, B. Boštjančič, V. Perevozchikov, Theodora Papadopoulou, B. Korzen, Jon Christopher Wikne, C. Defoix, E. I. Rosenberg, A. Campion, S. Volponi, B. Dalmagne, F. Fulda-Quenzer, H. P. Borner, Stefan Schael, A. Lipniacka, Paul Baillon, Alexander Lincoln Read, M. Szeptycka, Tiziano Camporesi, A.J. Camacho Rozas, Abdenour Lounis, M.-H. Gros, Laurent Chevalier, M. Fernandez Alonso, D. Radojicic, V. Obraztsov, Jan Ridky, P. Folegati, Z. Hajduk, K. Kurvinen, Maciej Górski, W. Ruckstuhl, Borge Svane Nielsen, J. J. Lozano, Guido Barbiellini, R. Zukanovich Funchal, B. Franek, H. Wahlen, Ariel Goobar, E. Graziani, P. S. Iversen, F. Fontanelli, Maria Roberta Monge, A. Zalewska, Krzysztof Doroba, N. G. Redaelli, R. Moeller, A. Hakansson, Chiara Meroni, J. H. Koehne, Marco Bozzo, T. Hofmokl, Marek Szczekowski, J. M. Brunet, H. Foeth, Roberto Cirio, I. Roncagliolo, L. K. Resvanis, J. E. Hooper, J. Guy, P. Lutz, W. Krupinski, W. T. Meyer, P. V. Chliapnikov, Tord Ekelof, H. Staeck, D. Benedic, P. Abreu, P. Borgeaud, J. P. Gerber, Tim Adye, E. Rosso, H. Klein, P. Beltran, Peter Kluit, F. Naraghi, P. Frenkiel, K. H. Becks, E. Vallazza, Milos Lokajicek, J. Cuevas Maestro, A. Chan, B. Ueberschaer, Massimo Caccia, H. J. Hilke, D. J. Holthuizen, F. Waldner, S. Haider, Antonio Ferrer, Tuure Tuuva, F. Simonetto, F. Kapusta, K. W. Glitza, Clara Troncon, G. Leder, B. Åsman, W.S.C. Williams, J.-E. Augustin, F. Ledroit, E.N. Gazos, M. Schaeffer, B. Loerstad, Eilam Gross, B. Nijjhar, E. Menichetti, Stefano Ragazzi, K. Furnival, C. Walck, A. De Angelis, P. Collins, D. Delikaris, Vladimir Nikolaenko, C. Caso, J. Drees, Fernand Grard, A. Passeri, D. Crennell, F. Mandl, T. Todorov, H. Burmeister, N. van Eijndhoven, J. Werner, L. Tortora, F. J. Harris, C. De La Vaissiere, C. J. Beeston, Daniel Bloch, F. Cao, Ahmimed Ouraou, Wolfgang Adam, M. L. Turluer, B. W. Heck, M. Mazzucato, P. Szymanski, Robert S. Brown, V.M. Golovatyuk, Carlos Lacasta, K. D. Brand, N. I. Zimin, Krzysztof A. Rybicki, H. B. Crawley, D. Isenhower, A. Pinsent, D. Wormald, K. Woschnagg, A. De Min, Joao Varela, V. Falaleev, M. Dracos, J. J. Gomez Y Cadenas, V. Chorowicz, D. Reid, Yu. Belokopytov, S. Squarcia, Matteo Pegoraro, E. C. Katsoufis, G. Gopal, E. G. Anassontzis, R. Holmes, H. Saarikko, M. Voutilainen, G. Grosdidier, W. Dulinski, K. A. J. Forbes, S. D. Hodgson, S. Ueberschaer, G. Galeazzi, J. P. Engel, P. Bambade, K. Moenig, M. V. Castillo Gimenez, E. J. Sanchez, M. Crozon, T. Buran, Gianni Zumerle, P. Roudeau, Alessandra Romero, J. Kesteman, A. Maltezos, G. Damgaard, F. Verbeure, C. Bricman, M. A E Schyns, Martino Margoni, P. F. Honore, E. Fokitis, G. D. Alekseev, Olga Botner, M. Michelotto, V. Gracco, Pavlos Ioannou, Krzysztof Korcyl, A. N. Sissakian, R. Llosa, Claudia J. Stubenrauch, Carmen García, B. Jean-Marie, Mario Sannino, Eleuterio Spiriti, P. Poropat, Andromachi Tsirou, M. A. Houlden, M. Mc Cubbin, K. Hultqvist, Georgios Stavropoulos, P. David, Andre Augustinus, W. K. Van Doninck, F. Richard, W.-D. Apel, C. Matteuzzi, M. Hahn, D. Vilanova, S. Almehed, F. Hahn, S. Marti, U. Kruener-Marquis, Paolo Ronchese, N. J. Kjaer, Paula Eerola, Lucio Cerrito, M. A. Winter, G. E. Kalmus, H. Palka, G. Skjevling, J. W. Lamsa, F. Barao, T. Henkes, B. De Lotto, G. Crosetti, Evgueni Vlasov, E. Higon, R. Seufert, H. Herr, F. Scuri, A. M. Wetherell, L. G. Tkatchev, Jmv Garcia, L. Lanceri, A. Firestone, M. Vollmer, U. Rossi, Paolo Giacomelli, R. Sekulin, S. Delorme, M. Zito, J. J. Hernandez, T. Moa, G. Maehlum, B. Grossetete, Allan Hallgren, Giovanni Valenti, Antonio Baroncelli, Guenakh Mitselmakher, Fares Djama, José Salt, L. Vibert, M. Jonker, William Trischuk, A. Markou, Cristian Stanescu, P. Branchini, H. Schneider, R. Lauhakangas, Tiziano Rovelli, Mikael Berggren, G. Kantardjian, M. Sessa, M. Los, V. Lepeltier, M. Donszelmann, H. Forsbach, C. Ronnqvist, Paolo Checchia, G. Zhang, A. P. Ostankov, Ph. Gavillet, R. Gokieli, Dietrich Liko, P. Privitera, V. Kostukhin, R. Zitoun, M. Turala, Luc Pape, P. Herquet, R. Contri, Piotr Zalewski, U. Nau-Korzen, Manolis Dris, E. Lillethun, V.A. Uvarov, Daniel Treille, J. N. Jackson, P. Kokkinias, J. Lindgren, Nikita Smirnov, F. Carena, Pierre Billoir, M. Pernicka, I. Hietanen, Jose M. Benlloch, A. Grant, Vaclav Vrba, Hans Dijkstra, G. Lenzen, J. E. Campagne, M. Koratzinos, P. Negri, J.H. Bibby, Göran Jarlskog, A. Letessier-Selvon, J. Dolbeau, P.S.L. Booth, P. N. Ratoff, A. Lopez-Fernandez, J. Marco, M. P. Clara, Maria Elena Pol, S. Katsanevas, D. Y. Bardin, T. A. Filippas, M. Regler, P. Yepes, H. Mueller, C. O. Higgins, B. Bouquet, R. Orava, A. Klovning, Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), CMS, Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), L3, Acciarri, M., Achard, P., Adriani, O., Aguilar Benitez, M., Alcaraz, J., Alemanni, G., Allaby, J., Aloisio, Alberto, Alviggi, Mariagrazia, Ambrosi, G., Anderhub, H., Andreev, V. P., Angelescu, T., Anselmo, F., Arefiev, A., Azemoon, T., Aziz, T., Bagnaia, P., Bajo, A., Baksay, L., Balandras, A., Banerjee, S., Barczyk, A., Barillere, R., Barone, L., Bartalini, P., Basile, M., Battiston, R., Bay, A., Becattini, F., Becker, U., Behner, F., Bellucci, L., Berbeco, R., Berdugo, J., Berges, P., Bertucci, B., Betev, B. L., Bhattacharya, S., Biasini, M., Biland, A., Blaising, J. J., Blyth, S. C., Bobbink, G. J., Bohm, A., Boldizsar, L., Borgia, B., Bourilkov, D., Bourquin, M., Braccini, S., Branson, J. G., V, B., Brochu, F., Buffini, A., Buijs, A., Burger, J. D., Burger, W. J., Cai, X. D., Campanelli, M., Capell, M., Romeo, G. C., Carlino, G., Cartacci, A. M., Casaus, J., Castellini, G., Cavallari, F., Cavallo, N., Cecchi, C., Cerrada, M., Cesaroni, F., Chamizo, M., Chang, Y. H., Chaturvedi, U. K., Chemarin, M., Chen, A., Chen, G., Chen, G. M., Chen, H. F., Chen, H. S., Chiefari, Giovanni, Cifarelli, L., Cindolo, F., Civinini, C., I, C., Clare, R., Coignet, G., Colijn, A. P., Colino, N., Costantini, S., Cotorobai, F., Cozzoni, B., B. d., La, Csilling, A., Cucciarelli, S., Dai, T. S., Van, J. A., D'Alessandro, R., Asmundis, R. d., Deglon, P., Degre, A., Deiters, K., DELLA VOLPE, Domenico, Denes, P., Denotaristefani, F., Salvo, A. D., Diemoz, M., Dierendonck, D. v., Lodovico, F. D., Dionisi, C., Dittmar, M., Dominguez, A., Doria, A., Dova, M. T., Duchesneau, D., Dufournaud, D., Duinker, P., I, D., Mamouni, H. E., Engler, A., Eppling, F. J., Erne, F. C., Extermann, P., Fabre, M., Faccini, R., Falagan, M. A., Falciano, S., Favara, A., Fay, J., Fedin, O., Felcini, M., Ferguson, T., Ferroni, F., Fesefeldt, H., Fiandrini, E., Field, J. H., Filthaut, F., Fisher, P. H., I, F., Forconi, G., Fredj, L., Freudenreich, K., Furetta, C., Galaktionov, Y., Ganguli, S. N., Garcia Abia, P., Gataullin, M., Gau, S. S., Gentile, S., Gheordanescu, N., Giagu, S., Gong, Z. F., Grenier, G., Grimm, O., Gruenewald, M. W., Guida, M., Gulik, R. v., Gupta, V. K., Gurtu, A., Gutay, L. J., Haas, D., Hasan, A., Hatzifotiadou, D., Hebbeker, T., Herve, A., Hidas, P., Hirschfelder, J., Hofer, H., Holzner, G., Hoorani, H., Sr, H., Hu, Y., I, I., Jin, B. N., Jones, L. W., Jong, P. d., I, J., Khan, R. A., Kaur, M., Kienzle Focacci, M. N., Kim, D., Kim, J. K., Kirkby, J., Kiss, D., Kittel, W., Klimentov, A., Konig, A. C., Kopp, A., V, K., Kraber, M., Kraemer, R. W., Krenz, W., Kruger, A., Kunin, A., P. L., De, I, L., Landi, G., Lassila Perini, K., Lebeau, M., Lebedev, A., Lebrun, P., Lecomte, P., Lecoq, P., Coultre, P. L., Lee, H. J., J. M., Le, Leiste, R., Leonardi, E., Levtchenko, P., Li, C., Lokhoded, S., Lin, C. H., Lin, W. T., Linde, F. L., Lista, L., Liu, Z. A., Lohmann, W., Longo, E., Y. S., Lu, Lubelsmeyer, K., Luci, C., Luckey, D., Lugnier, L., Luminari, L., Lustermann, W., W. G., Ma, Maity, M., Malgeri, L., Malinin, A., Mana, C., Mangeol, D., Mans, J., Marchesini, P., Marian, G., Martin, J. P., Marzano, F., G. G. G., Mazumdar, K., Mcneil, R. R., Mele, S., Merola, Leonardo, Meschini, M., Metzger, W. J., Der, M. v., Mihul, A., Milcent, H., Mirabelli, G., Mnich, J., Mohanty, G. B., Molnar, P., Monteleoni, B., Moore, R., Moulik, T., Muanza, G. S., Muheim, F., A. J. M., Musy, M., Napolitano, Marco, Nessi Tedaldi, F., Newman, H., Niessen, T., Nisati, A., Nowak, H., Organtini, G., Oulianov, A., Palomares, C., Pandoulas, D., Paoletti, S., Paolucci, P., Paramatti, R., Park, H. K., Park, I. H., Pascale, G., Passaleva, G., Patricelli, Sergio, Paul, T., Pauluzzi, M., Paus, C., Pauss, F., Pedace, M., Pensotti, S., Perret Gallix, D., Petersen, B., Piccolo, D., Pierella, F., Pieri, M., Piroue, P. A., Pistolesi, E., V, P., Pohl, M., Postema, H., Pothier, J., Produit, N., Prokofiev, D. O., Prokofiev, D., Quartieri, J., Rahal Callot, G., Rahaman, M. A., Raics, P., Raja, N., Ramelli, R., Rancoita, P. G., Raspereza, A., Raven, G., Razis, P., Ren, D., Rescigno, M., Reucroft, S., Rhee, T. v., Riemann, S., Riles, K., Robohm, A., Rodin, J., Roe, B. P., Romero, L., Rosca, A., Rosier Lees, S., Rubio, J. A., Ruschmeier, D., Rykaczewski, H., Saremi, S., Sarkar, S., Salicio, J., Sanchez, E., Sanders, M. P., Sarakinos, M. E., Schafer, C., V, S., Schmidt Kaerst, S., Schmitz, D., Schopper, H., Schotanus, D. J., Schwering, G., Sciacca, Crisostomo, Sciarrino, D., Seganti, A., Servoli, L., Shevchenko, S., Shivarov, N., Shumilov, E., Shvorob, A., Siedenburg, T., Son, D., Smith, B., Spillantini, P., Steuer, M., Stickland, D. P., Stone, A., Stoyanov, B., Straessner, A., Sudhakar, K., Sultanov, G., Sun, L. Z., Suter, H., Swain, J. D., Szillasi, Z., Sztaricskai, T., Tang, X. W., Tauscher, L., Taylor, L., Tellili, B., Timmermans, C., S. C. C., Ting, S. M., Tonwar, S. C., Toth, J., Tully, C., Tung, K. L., Uchida, Y., Ulbricht, J., Valente, E., Vesztergombi, G., I, V., Vicinanza, D., Viertel, G., Villa, S., Vivargent, M., Vlachos, S., Vogel, H., Vogt, H., Vorobyov, A. A., Vorvolakos, A., Wadhwa, M., Wallraff, W., Wang, M., Wang, X. L., Wang, Z. M., Weber, A., Weber, M., Wienemann, P., Wilkens, H., S. X., Wu, Wynhoff, S., Xia, L., Z. Z., Xu, Yamamoto, J., Yang, B. Z., Yang, C. G., Yang, H. J., Yang, M., J. B., Ye, Yeh, S. C., Zalite, A., Zalite, Y., Zhang, Z. P., Zhu, G. Y., Zhu, R. Y., Zichichi, A., Ziegler, F., Zilizi, G., Zoller, M., L3 (IHEF, IoP, FNWI), LEP (IHEF, IoP, FNWI), Achard, Pablo, Ambrosi, Giovanni, Bourquin, Maurice, Braccini, Saverio, Chamizo Llatas, Maria, Deglon, Patrick, Extermann, Pierre, Field, John, Kienzle, Maria-Novella, Pohl, Martin, Sciarrino, Deborah, Aguilarbenitez, M., Ahlen, S., Alpat, B., Alverson, G., Antreasyan, D., Ball, R. C., Banicz, K., Baschirotto, A., Bilei, G. M., Bock, R., Boucham, A., Boutigny, D., Brigljevic, V., Brock, I. C., Busenitz, J., Buytenhuijs, A., Caria, M., Chan, A., Cheng, H. S., Chen, M., Chien, C. Y., Choi, M. T., Clare, I., Cohn, H. O., Cotorbai, F., Delacruz, B., Dalessandro, R., Deasmundis, R., Deboeck, H., Dibitonto, D., Vandierendonck, D., Dilodovico, F., Dorne, I., Drago, E., Duran, I., Dutta, S., Easo, S., Efremenko, Y., Elmamouni, H., Ernenwein, J. P., Fenyi, B., Fernandez, D., Garciaabia, P., Gerald, J., Goldfarb, S., Goldstein, J., Gougas, A., Gratta, G., Hangarter, K., Hartmann, B., Vanhoek, W. C., Hou, S. R., Hu, G., Innocente, V., Janssen, H., Dejong, P., Josamutuberria, I., Kasser, A., Kamyshkov, Y., Kapinos, P., Kapustinsky, J. S., Karyotakis, Y., Kienzlefocacci, M. N., Kim, S. C., Kim, Y. G., Kinnison, W. W., Kirkby, A., Kirkby, D., Korolko, I., Koutsenko, V., Kuijten, H., Deguevara, P. L., Lapoint, C., Lassilaperini, K., Laurikainen, P., Lecoultre, P., Lee, J. S., Lee, K. Y., Leggett, C., Legoff, J. 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- Subjects
COLLISIONS ,Nuclear and High Energy Physics ,Particle physics ,LUND MONTE-CARLO ,PAIR PRODUCTION ,Electron–positron annihilation ,FOS: Physical sciences ,Elementary particle ,ddc:500.2 ,01 natural sciences ,7. Clean energy ,Resonance (particle physics) ,JET FRAGMENTATION ,DECAYS ,High Energy Physics - Experiment ,Nuclear physics ,Particle decay ,High Energy Physics - Experiment (hep-ex) ,0103 physical sciences ,[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex] ,SILICON MICROVERTEX DETECTOR ,PRECISE MEASUREMENT ,Limit (mathematics) ,QCD ANALYSIS ,010306 general physics ,L3 EXPERIMENT ,Coupling constant ,Physics ,Muon ,Annihilation ,TEST BEAM ,E+E-PHYSICS ,010308 nuclear & particles physics ,ALPHA(S) ,High Energy Physics::Phenomenology ,Detector ,Pair production ,SPECTRAL FUNCTIONS ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,High Energy Physics::Experiment ,Particle Physics - Experiment ,Lepton - Abstract
The tau lepton lifetime is measured with the L3 detector at LEP using the complete data taken at centre-of-mass energies around the Z pole resulting in tau_tau = 293.2 +/- 2.0 (stat) +/- 1.5 (syst) fs. The comparison of this result with the muon lifetime supports lepton universality of the weak charged current at the level of six per mille. Assuming lepton universality, the value of the strong coupling constant, alpha_s is found to be alpha_s(m_tau^2) = 0.319 +/- 0.015(exp.) +/- 0.014 (theory). The tau lepton lifetime is measured with the L3 detector at LEP using the complete data taken at centre-of-mass energies around the Z pole resulting in τ τ =293.2 ± 2.0 (stat) ± 1.5 (syst) fs . The comparison of this result with the muon lifetime supports lepton universality of the weak charged current at the level of six per mille. Assuming lepton universality, the value of the strong coupling constant, α s is found to be α s ( m τ 2 ) = 0.319 ± 0.015 (exp) ± 0.014 (theory). The tau lepton lifetime is measured with the L3 detector at LEP using the complete data taken at centre-of-mass energies around the Z pole resulting in tau_tau = 293.2 +/- 2.0 (stat) +/- 1.5 (syst) fs. The comparison of this result with the muon lifetime supports lepton universality of the weak charged current at the level of six per mille. Assuming lepton universality, the value of the strong coupling constant, alpha_s is found to be alpha_s(m_tau^2) = 0.319 +/- 0.015(exp.) +/- 0.014 (theory).
- Published
- 2015
43. Local border traffic and the development of retail trade in the Kaliningrad region and Polish borderlands
- Author
-
Oleg Bolychev, Tatyana Yu. Kuznetsova, and Ivan S. Gumenyuk
- Subjects
National Economy ,Cultural Studies ,History ,Volkswirtschaftstheorie ,local border traffic ,Sociology and Political Science ,Economics ,Geography, Planning and Development ,International trade ,lcsh:Regional economics. Space in economics ,Internationale Beziehungen ,Geopolitics ,Russia ,cross-border cooperation ,Retail sales ,Kaliningrad region Polish border voivodeships ,Political science ,ddc:330 ,media_common.cataloged_instance ,European union ,retail trade ,media_common ,Grenzgebiet ,retail, cross-border cooperation, local border traffic, Kaliningrad region Polish border voivodeships ,Polen ,business.industry ,Wirtschaft ,retail ,grenzüberschreitende Zusammenarbeit ,International Relations, International Politics, Foreign Affairs, Development Policy ,lcsh:HT388 ,Einzelhandel ,Economy ,Currency ,border region ,Retail trade ,Russland ,Russian federation ,Poland ,International relations ,internationale Beziehungen, Entwicklungspolitik ,business ,General Economics, Econometrics and Finance ,Social Sciences (miscellaneous) ,ddc:327 - Abstract
102 Signing the agreement on local border traffic (LBT) between the Republic of Poland and the Russian Federation was welcomed by experts as an important step towards the future visa-free regime between the European Union and the Russian Federation often discussed in the international dialogue. The three years of LBT mechanism have shown its practical significance for the development of research and cultural contacts, cooperation between municipalities and NGOs of the Kaliningrad region and the borderland (Pomeranian and Warmian-Masurian) voivodeships of Poland. When considering retail trade as a structural element of economy, it is important to address the differences in the effect LBT has had on the development of this sector in the Kaliningrad region and the neighbouring Polish voivode-ships. According to Russian experts, LBT results in 7—20 % losses in the Kaliningrad region’s retail sales, whereas in Poland LBT stimulates retail trade (accounting for 12 % of sales in the border voivodeships). This article analyses the role of LBT in the development of retail trade in the Kaliningrad region and the Polish border voivodeships as well as prospects of its development in view of the changing geopolitical situation and adjustment of the currency exchange rates at the end of 2014. Based on statistics and analytical data, the authors arrive at the conclusion that the positive effect of LBT outdoes its negative impact on various sectors of the border regions’ economies, including retail trade.
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- 2015
44. [Automatic morphometric analysis as a method for determining the level of extracellular matrix components and for quantifying nuclear antigens]
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V A Krutova, T. V. Gaivoronskaya, L. M. Chuprinenko, E. A. Gubareva, I. S. Gumenyuk, E. V. Kuevda, S. N. Alekseenko, S. E. Gumenyuk, and A. S. Sotnichenko
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0301 basic medicine ,Pathology ,medicine.medical_specialty ,02 engineering and technology ,Biology ,Pathology and Forensic Medicine ,Extracellular matrix ,03 medical and health sciences ,medicine ,Image Processing, Computer-Assisted ,Humans ,Biotechnology research ,Coloring Agents ,Analysis method ,Antigens, Nuclear ,021001 nanoscience & nanotechnology ,Immunohistochemistry ,Extracellular Matrix ,030104 developmental biology ,Morphometric analysis ,Deconvolution ,0210 nano-technology ,Biological system ,Quantitative analysis (chemistry) ,Algorithms ,Software - Abstract
Automated image analysis methods are highly important for biotechnology research. The authors developed and tested a program for the morphometric analysis of photomicrographs of the sections processed using the standard immunohistochemical examination protocols. The color deconvolution method used in the algorithm was proven to be effective in mapping the distribution of DAB chromogen in the sample containing multiple dyes. The experiment demonstrated that the level of extracellular matrix proteins could be comparatively quantified in different groups of samples. The effective methods for the quantitative analysis of the Ki-67 labelling index were also tested using the same algorithms. The developed program was published under free GPL 3.0.Автоматизированные методы анализа изображения являются весьма актуальными в биотехнологических исследованиях. Авторы разработали и протестировали программу для морфометрического анализа микрофотографий срезов, обработанных по стандартным протоколам иммуногистохимического исследования. Метод цветовой деконволюции, использованный в алгоритме, оказался эффективным для выделения карты распределения DAB-хромогена в образце, содержащем несколько красителей. В эксперименте продемонстрирована возможность сравнительного количественного анализа содержания белков внеклеточного матрикса в различных группах образцов. Также была протестирована эффективная методика количественного анализа индекса метки Ki-67 с использованием тех же алгоритмов. Разработанная программа опубликована под свободной лицензией GPL 3,0.
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- 2017
45. [Experimental development and rationale for a renal decellularization protocol with subsequent comprehensive assessment of the biological scaffold]
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A S Sotnichenko, E. V. Kuevda, E. A. Gubareva, I Kh Egiev, V N Chechelyan, S. S. Dzhimak, I S Gumenyuk, R Z Nakokhov, A. A. Basov, P V Glybochko, Yu V Teterin, S N Alekseenko, and O M Lyasota
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Pathology ,medicine.medical_specialty ,medicine.medical_treatment ,Cell Separation ,Bioinformatics ,Kidney ,Regenerative medicine ,Tissue engineering ,Medicine ,Animals ,Renal replacement therapy ,Decellularization ,Tissue Engineering ,Tissue Scaffolds ,business.industry ,Mesenchymal stem cell ,General Medicine ,medicine.disease ,Rats ,Transplantation ,medicine.anatomical_structure ,Kidney Failure, Chronic ,business ,Kidneys, Artificial ,Kidney disease - Abstract
Chronic renal failure (CRF) is one of the most challenging problems of contemporary medicine. Patients with chronic renal failure usually need renal replacement therapy as either hemodialysis, peritoneal dialysis or a kidney transplant. The latter is the most promising option for end-stage kidney disease. However, the shortage of donor organs, the complexity of their delivery, the difficulty in finding an immunologically compatible donor and the need for lifelong immunosuppression triggered advances in modern tissue engineering. In this field, the primary priority is focused on developing bioengineered scaffolds with subsequent recellularization with autologous cells. Using such constructs would allow for solving both ethical and immunological problems of transplantation. The aim of this pilot study was to develop a new method of renal decellularization using small laboratory animals. Materials and methods The study investigated the morphological structure of the obtained decellularized matrix and quantitatively tested DNA residues in the resulting scaffold. We proposed a new biophysical method for assessing the matrix quality using the EPR spectroscopy and conducted experiments on the matrix recellularization with mesenchymal multipotent stem cells to estimate cytotoxicity, cell viability and metabolic activity. Results The obtained decellularized renal matrix retained the native tissue architecture after a complete removal of the cell material, had no cytotoxic properties and supported cell adhesion and proliferation. Conclusion All the above suggests that the proposed decellularization protocol is a promising method to produce tissue-engineered kidney constructs with possible clinical application in the foreseeable future.
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- 2017
46. [Familial multiple sclerosis in Tomsk region]
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N. F. Musina, Valentina M. Alifirova, E. Terskikh, M. Titova, Ya. S. Gumenyuk, and A. A. Sjomkina
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Pediatrics ,medicine.medical_specialty ,Multiple Sclerosis ,Population ,Disease ,Pathogenesis ,03 medical and health sciences ,0302 clinical medicine ,Polymorphism (computer science) ,medicine ,Genetic predisposition ,Prevalence ,Humans ,030212 general & internal medicine ,Registries ,Age of Onset ,education ,Child ,education.field_of_study ,Polymorphism, Genetic ,business.industry ,Multiple sclerosis ,medicine.disease ,Psychiatry and Mental health ,Etiology ,Disease Progression ,Neurology (clinical) ,Age of onset ,business ,030217 neurology & neurosurgery - Abstract
Multiple sclerosis (MS) has a multifactorial etiology. To explore a role of genetic factors in the pathogenesis of MS, the authors studied familial cases of MS.For an analysis of familial cases, a database of 320 MS patients registered in Tomsk region since 1980 till 2014 was used. The following items for each patient were recorded: disease onset, manifestation of disease, duration of first remission, rate of progression of disease.Nine families with several members with MS were identified. In 2014, the frequency of familial cases in the MS population of Tomsk region was 4.7%. The prevalence of familial MS was 1.4 cases per 100.000 of people. The younger age at disease onset and higher rate of disease progression measured with the EDSS in parent-child pairs were identified. The most families with several members with MS were characterized by clinical polymorphism of onset, duration and rate of disease progression.Цель исследования. Рассеянный склероз (РС) имеет мультифакторную природу. Для исследований роли генетической составляющей в патогенезе заболевания актуальным является изучение семейных случаев РС. Последнее было целью настоящей работы. Материал и методы. Для анализа семейных случаев РС использованы данные о 320 больных РС, зарегистрированных в Томской области с 1980 по 2014 г. В отношении каждого пациента определяли такие показатели, как возраст больного в период начала болезни, ее первые симптомы, длительность первой ремиссии, скорость прогрессирования болезни. Результаты и заключение. Выявлено 9 семей с повторными случаями РС у родственников. Частота семейного РС в Томской области в 2014 г. составила 4,7% от общего числа больных РС, распространенность семейного РС - 1,4 случая на 100 тыс. населения. Установлено более раннее начало заболевания у детей, родители которых больны РС, а также более быстрое нарастание инвалидизации у первых по шкале EDSS. Большинство семей отличает клинический полиморфизм дебюта, течения и скорости прогрессирования заболевания.Цель исследования. Рассеянный склероз (РС) имеет мультифакторную природу. Для исследований роли генетической составляющей в патогенезе заболевания актуальным является изучение семейных случаев РС. Последнее было целью настоящей работы. Материал и методы. Для анализа семейных случаев РС использованы данные о 320 больных РС, зарегистрированных в Томской области с 1980 по 2014 г. В отношении каждого пациента определяли такие показатели, как возраст больного в период начала болезни, ее первые симптомы, длительность первой ремиссии, скорость прогрессирования болезни. Результаты и заключение. Выявлено 9 семей с повторными случаями РС у родственников. Частота семейного РС в Томской области в 2014 г. составила 4,7% от общего числа больных РС, распространенность семейного РС — 1,4 случая на 100 тыс. населения. Установлено более раннее начало заболевания у детей, родители которых больны РС, а также более быстрое нарастание инвалидизации у первых по шкале EDSS. Большинство семей отличает клинический полиморфизм дебюта, течения и скорости прогрессирования заболевания.
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- 2017
47. Prospects of macacamulatta’s mesenchymal multipotent stromal cells usage for tissue -engineered scaffolds creation
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E. A. Gubareva, Еlena Kuevda, Ramazan Nakohov, Dzhina D Karal-Ogly, Alexander Sotnichenko, I. V. Gilevich, Sergey Orlov, and I. S. Gumenyuk
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Stromal cell ,Tissue engineered ,Chemistry ,Mesenchymal stem cell ,General Medicine ,Cell biology - Published
- 2017
48. A spatial study of networking in the Vistula Lagoon region using geoinformation systems
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Nikolai Belov, Ivan S. Gumenyuk, and Vladimir A. Gritsenko
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History ,Volkswirtschaftstheorie ,Geographic information system ,Sociology and Political Science ,Economics ,Geography, Planning and Development ,Geoinformationssystem ,lcsh:Regional economics. Space in economics ,Geopolitics ,geography ,Russia ,information system ,Geographie ,Kooperation ,wirtschaftliche Zusammenarbeit ,Regional science ,regionale Verflechtung ,geoinformation system ,Wirtschaft ,lcsh:International relations ,lcsh:HT388 ,Netzwerk ,Geography ,cross-border region ,Russland ,Informationssystem ,internationale Beziehungen, Entwicklungspolitik ,General Economics, Econometrics and Finance ,lcsh:JZ2-6530 ,National Economy ,Cultural Studies ,Urban studies ,cooperation ,Internationale Beziehungen ,network cooperation ,Vistula Lagoon ,Component (UML) ,ddc:330 ,Set (psychology) ,Structure (mathematical logic) ,business.industry ,economic cooperation ,International Relations, International Politics, Foreign Affairs, Development Policy ,network ,Key (cryptography) ,Position (finance) ,International relations ,business ,regional interdependence ,Social Sciences (miscellaneous) ,ddc:327 - Abstract
29 Network cooperation — the most efficient form of unlocking the economic and natural potential of territories — is rapidly developing in Russia under the influence of global processes. Due to its unique geopolitical position, the Kaliningrad region is one of the regions where such networks develop at both the regional and international levels. When studying such forms of cooperation, the traditional methods of social sciences as research tools are not sufficient. It can be explained by the dynamic nature of network cooperation as well as by the fact that it involves a significant number of independent agents. We believe that one of the important tools of research on network cooperation is regional integral geoinformation systems (GIS). Modern GIS are successfully used in related fields, such as environmental and climate studies, geology, urban studies, and serve as rather efficient tools of analysing spatial objects and phenomena. One of such systems has been developed and is successfully functioning at the Immanuel Kant Baltic Federal University, which makes it possible to use it in studying network cooperation in the framework of crossborder development with the involvement of Kaliningrad municipalities. The key objective set by the authors of the article is to justify the need for studying the emerging network cooperation with the help of both traditional methods of geography and modern GIS; a specific case is made of the crossborder Vistula lagoon region — the one that brings together Russian and Polish municipalities. The authors provide with the background for the search of possible development strategies in the region, and note that the creation of a regional GIS structure can become a necessary component of the region’s information and communication structure; this conclusion can be considered the key result of the research conducted. The practical significance of the article lies in justifying the use of modern geoinformation systems as a tool of territory development as well as for the purpose of making efficient managerial decisions at different levels.
- Published
- 2013
49. Measurement of inclusive π 0 production in hadronic Z 0 decays
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F. Simonetto, G. Leder, B. Åsman, V. Lefebure, D. Crennell, F. Mandl, G. Smadja, Patrick Jarry, G. Rinaudo, J. Salt, Z. Krumstein, L.N. Gerdyukov, T. Tabarelli, H. Palka, A. De Min, A. Trombini, I. Siccama, G. Sajot, P. Rebecchi, H. Rahmani, M. Blume, F. Barao, R. Mc Nulty, H. De Boeck, B. Jean-Marie, M. Tyndel, A. Deghorain, T. Buran, Markus Elsing, D. Fassouliotis, Ariella Cattai, F. Ledroit, J. Fuster, J.D. Richardson, Richard Jacobsson, O. Smirnova, A. N. Sisakian, A. Petrolini, A. Sadovsky, S. C. Blyth, G. Wilkinson, E. Higon, J. M. Lopez, Leif J. Jönsson, Borge Svane Nielsen, S. De Brabandere, B. De Lotto, G. Crosetti, Evgueni Vlasov, C. Joram, Andrei Nomerotski, J. Dolbeau, P. Bambade, C. Maocun, S. Bosworth, A. Lopez-Fernandez, R. Zuberi, Krzysztof Doroba, A. Passeri, F. Scuri, Chiara Meroni, P. Bruckman, G. W. Van Apeldoorn, L. Ventura, K. Yip, R. Lindner, J. W. Lamsa, Y. Lemoigne, Kathy Huet, Valeriy Pozdniakov, Olga Botner, M. Weierstall, Christine Kourkoumelis, E. Dahl-Jensen, T. Bolognese, K. Kurvinen, P.S.L. Booth, Per Jönsson, Norbert Neumeister, H. Herr, G. Transtromer, Chiara Mariotti, L. G. Tkatchev, Manfred Krammer, A. M. Wetherell, Charles Bricman, P. Kubinec, Peter Kluit, Clara Troncon, Carmen García, A. Seitz, J. P. Tavernet, M. Michelotto, D. Wicke, Javier Sánchez, L. Lanceri, G. Vegni, J. Van Eldik, Stéphane Plaszczynski, I. Lippi, T. S. Hill, H. Foeth, W. Bonivento, I. Stavitski, M. Schimmelpfennig, C. Zacharatou, P. Carrilho, J. J. Hernandez, J. Garcia, Kerem Cankocak, O. Podobrin, M.A. Lopez Aguera, S. Hahn, Francesca Romana Cavallo, M. Berggren, J. H. Wickens, B. Muryn, Marco Paganoni, Jose Luis Contreras, P. Delpierre, B. Ueberschaer, Paul Baillon, D. Zontar, Alexander Lincoln Read, A. Galloni, S. O. Holmgren, A. Klovning, Y. Arnoud, U. Mjoernmark, C. Bosio, P. B. Renton, E. I. Rosenberg, M. Szeptycka, Konstantinos Papageorgiou, H. T. Phillips, Vladimir Cindro, D. C. Fries, Louis Lyons, L. S. Vertogradov, M. Gibbs, R. Aleksan, W. Kucewicz, Tord Ekelof, Piotr Zalewski, B. Marechal, E. C. Katsoufis, A. De Angelis, S. Hoorelbeke, P. Herquet, Marta Calvi, Vincenzo Canale, V. V. Lapin, Geoffrey Smith, C. De Clercq, Marc Winter, G. Myatt, P. Collins, Maurizio Canepa, V. Obraztsov, K. D. Brand, W. J. Murray, L. Vitale, H. B. Crawley, D. Gele, M. Davenport, P. P. Allport, N. I. Zimin, S. Ragazzi, N. Redaelli, B. Golob, C. Kreuter, F. Dupont, P. Seager, Paolo Ronchese, A. G. Frodesen, O. Yushchenko, N. J. Kjaer, W. Oberschulte-Beckmann, E. K. Johansson, G. A. Chelkov, B. Loerstad, H. Wahlen, I. Roncagliolo, Klaus Hamacher, Daniel Bloch, D. Radojicic, Steinar Stapnes, M. Verlato, Ahmimed Ouraou, Tiziano Camporesi, G. Cosme, Juan Abel Barrio, R. C. Shellard, L. Di Ciaccio, Josef Hrubec, T. Burgsmueller, N. Vassilopoulos, Maria Elena Pol, J. Chauveau, S. Katsanevas, Jan Krolikowski, Luiz Mundim, N. N. Khovanski, W. Bartl, Z. Hajduk, Maciej Górski, Demetrios Loukas, I. A. Tyapkin, V.A. Uvarov, R. A. Brenner, Robert S. Brown, S. J. Alvsvaag, E. Agasi, V. Ruhlmann-Kleider, K. H. Becks, P. Lutz, G. Tristram, P. J. Holt, Marco Bozzo, M. L. Andrieux, Manolis Dris, R. Moeller, M. Petrovyck, W. Krupinski, R. Sekulin, V. Nikolaenko, P. Frenkiel, M. Karlsson, A. M. Segar, Sandra Amato, T. A. Filippas, K. Belous, M. Regler, F. Fontanelli, J. P. Laugier, E. Vallazza, T. Moa, M. Pimenta, B. A. Khomenko, R. Barate, P. Roudeau, C. Vander Velde, G. Valenti, Matteo Pegoraro, A. Firestone, L. K. Resvanis, J. Baudot, I. V. Ajinenko, C. Walck, M. S. Bilenky, V. Malychev, Massimo Caccia, L.J. Carroll, A. Buys, A. Normand, C. Weiser, R. Ehret, A. Romero, P. V. Chliapnikov, Imad Baptiste Laktineh, D. Y. Bardin, S. Squarcia, H. Saarikko, Yu. Sedykh, Francesco Navarria, Alberto Benvenuti, W.S.C. Williams, P. Langefeld, Lucio Cerrito, T. Maron, Mogens Dam, H. Mueller, F. Pierre, Vincent Hedberg, A. Ferrer, Ugo Amaldi, J. Medbo, W. De Boer, E. Zevgolatakos, G. Sciolla, G. Maehlum, P. Juillot, D. W. Lane, P. Antilogus, Fabio Cossutti, J. N. Jackson, P. Pages, P. Weilhammer, H. J. Hilke, M. Battaglia, V. Chorowicz, D. Vilanova, J-C. Marin, B. Erzen, R. Gokieli, L. Gorn, Amiran Tomaradze, Fares Djama, O. Ullaland, R. Lauhakangas, Ph. Charpentier, T. Brenke, M. Zito, G. Ekspong, Josef Strauss, V. Chabaud, M. Espirito Santo, W. Venus, T. Lesiak, J. Rames, W. Van Doninck, P. N. Ratoff, W. Neumann, P. Kokkinias, Y. Dufour, Sandor Czellar, P. Gunnarsson, Spyros Tzamarias, O. Tchikilev, B. Franek, S. Lamblot, L. Bugge, P. Niss, W. T. Meyer, K. Grzelak, M. Prest, Lydia Roos, M. Mazzucato, Allan Hallgren, S. Simonetti, M. Begalli, R. Nicolaidou, A. J. Camacho Rozas, I. Kronkvist, J. P. Gerber, C. K. Legan, G. Polok, R. Orava, M. Donszelmann, Yu. Gouz, Danilo Zavrtanik, F. Stichelbaut, P. Buschmann, R. Mc Kay, C. Martinez-Rivero, J. Drees, William Trischuk, A. Markou, G. Eigen, A. Andreazza, Evangelos Gazis, Tiziano Rovelli, B. Bouquet, Ernesto Migliore, D. Z. Toet, P. Siegrist, P. H. Kramer, I. Ripp, R. Keranen, F. Zach, S. S. Meyer, R. Janik, Stanislav Nemecek, Francisco Matorras, N. Pukhaeva, Pierre Billoir, D. Souza-Santos, G. Della Ricca, B. Tome, Th. D. Papadopoulou, M. Dracos, L. Chaussard, J. Dahm, C. Defoix, F. Fulda-Quenzer, E. Graziani, J. E. Augustin, J. M. Brunet, D. J. Holthuizen, Cristian Stanescu, P. Branchini, P. A. Fischer, Vaclav Vrba, H. Schneider, Y. Sacquin, Hans Dijkstra, C. Gaspar, T. L. Hessing, R. Contri, Wolfgang Adam, G. C. Zucchelli, Yu. Belokopytov, V. Lepeltier, Paolo Checchia, Ph. Gavillet, R. Henriques, M. Kaiser, M. Gunther, J. MacNaughton, C. Caso, Rupert Leitner, G. Piana, Claire Bourdarios, P. Paganini, M. Nieuwenhuizen, G. Matthiae, Luc Pape, A. Maio, L. Brillault, J. P. Engel, M. V. Castillo Gimenez, Paul Dauncey, N. Demaria, G. Damgaard, V. Gracco, Klaus Moenig, M. A. Houlden, W. Da Silva, W. A. Mitaroff, F. Richard, P. Chochula, C. Matteuzzi, S. Almehed, R. Chierici, F. Hahn, F. Formenti, F. Cao, N. Ershaidat, V. Bocci, O. Kouznetsov, Martino Margoni, E. Fokitis, Luis Peralta, F. Kapusta, Ugo Gasparini, K. A. Drees, Guido Barbiellini, J. Guy, Marek Szczekowski, E. Rosso, H. Klein, Tim Adye, K. Osterberg, A. Baroncelli, P. Van Dam, G. D. Alekseev, C. De La Vaissiere, Mario Sannino, M. Mc Cubbin, K. Hultqvist, Gary John Barker, K. Woschnagg, A. Tilquin, L. De Paula, Pawel Jalocha, Barry King, E. Falk, M. J. Bates, E. Spiriti, M. Bonesini, R. Frühwirth, Toralf Bernhard Skaali, T. Spassov, D. Gamba, M. Witek, J. Timmermans, B. Dalmagne, F. Verbeure, B. Stugu, S. Gumenyuk, M. Gandelman, A. Lipniacka, Milos Lokajicek, D. Bertrand, L. Tortora, F. J. Harris, M. Pindo, E. Cortina, W. Ruckstuhl, Carlos Lacasta, Krzysztof A. Rybicki, G. Borisov, M. Baubillier, Achille Stocchi, A. M. Zaitsev, Alexander Vodopyanov, F. Bianchi, B. Koene, F. Parodi, E. Karvelas, J. Cuevas Maestro, T. Todorov, M. Wielers, K. Karafasoulis, M. L. Turluer, D. Reid, R. Sosnowski, P. Vincent, Gianni Zumerle, F. Naraghi, P. Poropat, Andromachi Tsirou, Andre Augustinus, Paolo Morettini, J. G. Loken, C. De Saint-Jean, P. Beilliere, S. Marti i Garcia, D. Edsall, G. Grosdidier, A. Ruiz, M. A E Schyns, W. Hao, O. Barring, A. Onofre, T. J. V. Bowcock, F. Carena, A. G. Olshevski, U. Schwickerath, Maria Roberta Monge, A. Zalewska, M. Pernicka, Jesus Marco, G. Lenzen, R. Strub, Jacques Lemonne, F. Martinez-Vidal, V. Kostioukhine, M. Koratzinos, Laurent Mirabito, M. Feindt, S. Sánchez Navas, P. Negri, P. Sponholz, Göran Jarlskog, G. P. Gopal, W. D. Apel, Dietrich Liko, P. Privitera, Chariclia Petridou, Branislav Sitar, M. Reale, Daniel Treille, M. Bigi, J. Ridky, C. Parkes, Nikita Smirnov, and Andrea Perrotta
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Scattering cross-section ,Physics ,Particle physics ,Photon ,Physics and Astronomy (miscellaneous) ,010308 nuclear & particles physics ,Hadron ,Function (mathematics) ,01 natural sciences ,Nuclear physics ,Distribution (mathematics) ,Electromagnetic calorimeter ,0103 physical sciences ,Production (computer science) ,010306 general physics ,Parton shower - Abstract
An analysis is presented of inclusiveπ 0 production inZ 0 decays measured with the DELPHI detector. At low energies,π 0 decays are reconstructed by using pairs of converted photons and combinations of converted photons and photons reconstructed in the barrel electromagnetic calorimeter (HPC). At high energies (up to $$x_p = 2 \cdot p_\pi /\sqrt s = 0.75$$ ) the excellent granularity of the HPC is exploited to search for two-photon substructures in single showers. The inclusive differential cross section is measured as a function of energy forqq andbb events. The number ofπ 0’s per hadronicZ 0 event isN(π 0)/Z 0 =9.2±0.2(stat)±1.0(syst) and forbb events the number ofπ 0’s is N(π 0)/bb=10.1±0.4(stat)±1.1(syst). The ratio of the number ofπ 0’s inbb events to hadronicZ 0 events is less affected by the systematic errors and is found to be 1.09±0.05±0.01. The measuredπ 0 cross sections are compared with the predictions of different parton shower models. For hadronic events, the peak position in theξ p=ln(1/xp) distribution isξ* p =3.90 −0.14 +0.24 . The average number ofπ 0’s from the decay of primary B hadrons is found to be N(B→π 0 X)/B hadron=2.78±0.15(stat)±0.60(syst).
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- 2016
50. Measurement of the partial width of the decay of the Z0 into charm quark pairs
- Author
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U. Kruener-Marquis, M. L. Turluer, D. Reid, D. Bertrand, P. Siegrist, P. Vaz, I. Lippi, J-C. Marin, P. Lutz, E. K. Johansson, D. Bollini, P. B. Renton, W. S. C. Williams, Spyros Tzamarias, P. Poropat, Andromachi Tsirou, P. V. Chliapnikov, Andre Augustinus, A. Wehr, Edoardo Castelli, D. Radojicic, E. Menichetti, E. Fokitis, Paula Eerola, D.N. Edwards, S. Biagi, Tiziano Rovelli, M. Cresti, S. Gawne, Wolfgang Adam, M. Davenport, J. Pyyhtia, R. Keranen, L. Paper, E. I. Rosenberg, P. Frenkiel, A. Passeri, V.A. Uvarov, A. M. Segar, V. Nikolaenko, G. Trustram, Tord Ekelof, H. Staeck, P. Kapusta, G. E. Kalmus, M. Kostrikov, F. Grard, V. Vrba, S. Squarcia, F. Cao, E. N. Gazis, B. Korzen, R.B. Kadyrov, Bengt Lund-Jensen, G. Ekspong, Giovanni Darbo, F. Couchot, A. A. Rademakers, W. T. Meyer, Anthony Lincoln Read, A. P. Ostankov, J. Bjarne, H. Palka, Itzhak Roditi, Natale Demaria, Gueorgui Chelkov, A. Ruiz, G. R. Wilkinson, C. Vander Velde, Wojciech Kucewicz, L. Tortora, T. Tuuva, J. N. Jackson, S. O. Holmgren, M. Szczekowski, G. Galeazzi, A. Ferrer, L. S. Vertogradov, Borge Svane Nielsen, H. Burmeister, F. Barao, Roberto Cirio, L. K. Resvanis, F. Simonetto, E. Lieb, J. J. Lozano, M. H. Gros, U. Nnau-Lorzen, M. S. Bilenky, S. Ferroni, P. Bambade, K. Kurvinen, P.S.L. Booth, J. Lindgren, L.J. Carroll, W. Klempt, L. Lyons, O. Doll, Krzysztof Doroba, George Kalkanis, Chiara Meroni, Robert S. Brown, Tiziano Camporesi, Klaus Hamacher, M. Bonapart, Massimo Caccia, J. G. Loken, S. D. Hodgson, C. Bricman, A. Pullia, M. I. Laakso, L. O. Eek, R. C. Shellard, Josef Hrubec, M. A. Winter, S. Simonetti, J. Maillard, T. A. Filippas, T. Hofmokl, S. Gumenyuk, R. A. Brenner, Ariella Cattai, P. Ronschese, D. Benedic, E. Higon, R. Seufert, F. Scuri, J. Sanxhez, A. M. Wetherell, Th. D. Papadopoulou, J. H. Bibby, Pierre Billoir, G. Cosme, A. Baroncelli, Marco Bozzo, M. J. Bates, B. De Lotto, Guenakh Mitselmakher, G. Crosetti, S. J. Alvsvaag, Leif J. Jönsson, Ugo Gasparini, D. C. Fries, P. Weilhammer, I. Belokopytov, D. Husson, I. A. Tyapkin, T. S. Spassoff, A. Campion, M. Pegoraro, M. Pernicka, G. Lenzen, R. Strub, J. E. Campagne, M. Koratzinos, L. Lanceri, Paul Baillon, E. C. Katsoufis, G. Myatt, E. Graziani, Mikko Voutilainen, P. S. Iversen, F. Fontanelli, H. Furstenau, E. Sanchis, A. Lopez-Fernandez, Marta Calvi, L. Di Ciaccio, C. Defoix, P. Szymanski, A. Firestone, N. Redaelli, J. Marco, S. Ueberschaer, F. Waldner, H. Wahlen, Ariel Goobar, Ugo Amaldi, H. Forsbach, J. W. Lamsa, Guido Barbiellini, H. Herr, L. G. Tkatchev, Jose M. Benlloch, A. Grant, Mogens Dam, C. Lambropoulos, Patrick Jarry, G. Rinaudo, Clara Troncon, J. Guy, W. De Boer, Geoffrey Smith, E.N. Tsyganov, J. H. Wickens, W. Dulinski, Jose Luis Contreras, A. Fenyuk, J. H. Koehne, M. Pimenta, K. Woschnagg, B. A. Khomenko, A. De Min, A. Stocchi, Joao Varela, Hans Dijkstra, A. Markou, T. Buran, N. De Groot, P. Beltran, M. Vollmer, P. Delpierre, Tim Adye, W. D. Apel, B. Franek, P. Kluit, M. Mazzucato, U. Rossi, C. Walck, Paolo Giacomelli, J. E. Hooper, Francesco Navarria, L. Vibert, K. H. Becks, G. W. Van Apeldoorn, M. P. Clara, G. D. Alekseev, P. Negri, J. M. Brunet, M. Jonker, Pierre Astier, J. Zúñiga, M. Boratay, P. Abreu, P. Borgeaud, R. Sekulin, A. Zalewska, M. Baubillier, K. D. Brand, E. Vallazza, L. Ventura, G. Hamel de Monchenault, H. Schneider, Göran Jarlskog, Jan Ridky, L. Mathis, T. Moa, M.A. Lopez Aguera, M. Mc Cubbin, K. Hultqvist, H. Borner, C. Pinori, B.D. Hyams, Mikael Berggren, S. Ragazzi, A. Sebastia, Francesca Romana Cavallo, Josef Strauss, E. Lillethum, A. Letessier-Selvon, Mitchell Wayne, P. Zalewski, V. Lepeltier, G. Kantarjian, B. Grossetete, Allan Hallgren, Vegni, Giovanni Valenti, F. Udo, W. Venus, G. Maehlum, I. Herbst, V. Ruhlmann, Paolo Checchia, Jacques Lemonne, J. Velasco, E. Rosso, H. Klein, Ph. Gavillet, V. V. Lapin, Hans Muller, Fares Djama, V. Canale, N. K. Visnevskiy, C. De Clercq, F. Kapusta, L. Bugge, J. Drees, P. D. Dauncey, N. J. Kjaer, A. J. Camacho Rozas, G. Sette, M. Sessa, Maria Elena Pol, G. Leder, Alexander Vodopyanov, B. Åsman, G. Zumerle, L. Cerrito, F. Bianchi, P. N. Bogolubov, F. Ledroit, Kjell Fransson, S. Katsanevas, P. Privitera, D. Z. Toet, T. Kreuzberger, D. Vilanova, Christine Kourkoumelis, E. Dahl-Jensen, M. Schaeffer, D. Y. Bardin, P. Beilliere, D. Crennell, W. Van Doninck, P. N. Ratoff, Andrea Perrotta, F. Alted, J. Dolbeau, F. Mandl, G. Smadja, A. Klovning, Daniel Treille, Paul Allen, R. Lucock, R. Sosnowski, Olga Botner, Krzysztof Korcyl, A. Tilquin, Jorge-Armando Benitez Garcia, U. Mjoernmark, R. Gokieli, B. W. Heck, P.I. Zarubin, J. J. Hernandez, J. Cuevas Maestro, P. O. Hulth, P. Yepes, M. Regler, C. J. Beeston, J. Krolikowski, N. Magnussen, P. Herquet, H. De Boeck, V. Falaleev, E. Daubie, P. Laurikainen, M. De Beer, M. R. Monge, B. Jean-Marie, S. Braibant, S. Tavernier, M. Tyndel, M. Bonesini, J. A. M. A. Buytaert, Y. Gouz, N. Crosland, G. Gopal, Y. Sacquin, Andrey Korytov, R. Llosa, H. Mueller, J.M. Gago, H. Foeth, D. Wormald, R. Contri, M. Fernandez Alonso, T. Bolognese, E. J. Sanchez, R. Orava, U. Trevisan, R. Zukanovich Funchal, M. Szeptycka, W. Bartl, J. Wikne, N. Smirnov, V. Perevozchikov, J. A. Valls Ferrer, M. Turala, Manolis Dris, J. P. Gerber, Mario Sannino, K. W. Glitza, P. Roudeau, G. Skjevling, J. P. Laugier, F. Stichelbaut, A. De Angelis, D. Delikaris, R. Dzhelyadin, D. Gamba, C. Stanescu, R. Lauhakangas, N. van Eijndhoven, E. Zevgolatakos, G. Voulgaris, F. Verbeure, Daniel Bloch, Ahmimed Ouraou, V.M. Golovatyuk, Marcos Dracos, B. Bouquet, Juan Fuster, M. Kopf, B. Dalmagne, Laurent Chevalier, R. Zitoun, F. Fulda-Quenzer, P. Kokkinias, Milos Lokajicek, J. Kesteman, E. G. Anassontzis, J. P. Engel, M. V. Castillo Gimenez, G. Damgaard, O. Pingot, V. Gracco, H. Saarikko, Pavlos Ioannou, A.K. Topphol, Klaus Moenig, M. A. Houlden, G. Matthiae, W. A. Mitaroff, F. Richard, M. Hahn, F. Naraghi, V. G. Timofeev, S. Almehed, K. Spang, F. Hahn, C. Matteuzzi, E. Lillestol, G. Grosdidier, Alessandra Romero, I.A. Gritsaenko, J. E. Augustin, A. Zaitsev, S. Haider, A. N. Sissakian, Claudia J. Stubenrauch, Eleuterio Spiriti, C. Caso, H. B. Crawley, P. Morettini, Pierre Juillot, B. Koene, A.N. Diddens, D. Loukas, M. Crozon, R. Pain, V. Obraztsov, O. Barring, S. Dagoret, P. Van Dam, Renato Turchetta, C. De La Vaissiere, G. Zhang, Pawel Jalocha, Barry King, R. Frühwirth, J. Timmermans, P. Branchini, G. E. Theodosiou, M.D.M. De Fez Laso, R. Moeller, A. Pinsent, N. Yamdagni, M. T. Trainor, Sandor Czellar, N. Brummer, G. Wormser, Pieter David, W. H. Range, W. Krupinski, S. Maltezos, H. J. Hilke, J. Skeens, G. Stavropoulos, V. Chorowicz, R. Mc Kay, N. I. Zimim, F. Adami, Jürgen H. Werner, Philippe Charpentier, Francisco Matorras, T. B. Skaali, F. J. Harris, A. G. Frodesen, Z. Hajduk, Maciej Górski, A. Hakansson, C. Bosio, E. Vlasov, R. Holmes, Delphi, Collaboration, Abreu, P., Adam, W., and Canale, Vincenzo
- Subjects
Nuclear and High Energy Physics ,Particle physics ,E+E ANNIHILATION ,Meson ,LUND MONTE-CARLO ,Electron–positron annihilation ,Hadron ,01 natural sciences ,JET FRAGMENTATION ,Charm quark ,Standard Model ,law.invention ,Nuclear physics ,PHYSICS ,ENERGY ,Pion ,D-STAR-MESON ,CROSS-SECTION ,law ,0103 physical sciences ,010306 general physics ,Collider ,Nuclear Experiment ,Boson ,Physics ,010308 nuclear & particles physics ,High Energy Physics::Phenomenology ,Physique des particules élémentaires ,Física nuclear ,High Energy Physics::Experiment ,Particle Physics - Experiment - Abstract
A determination of the partial width Γc̄ of the Z0 boson into charm quark pairs is presented, based on a total sample of 36 900 Z0 hadronic decays measured with the DELPHI detector at the LEP collider. The production rate of cc events is derived from the inclusive analysis of charged pions coming from the decay of charmed meson D*+-→D0π+ and D*-→D̄0π- where the π± is constrained by kinematics to have a low pT with respect to the jet axis. The probability to procedure these π± from D*± decay in cc events is taken to be 0.31±0.05 as measured at √S = 10.55 GeV. The measured relative partial width Γ∞/Γh = 0.162± 0.030(stat.) ± 0.050(syst.) is in good agreement with the standard model value of 0.171. Together with our previous measurement of the total hadronic width Γh this implies Γ∞ = 282 ± 53 (stat.) ± 88 (syst.) MeV., 0, SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2016
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