11 results on '"S. Doublet"'
Search Results
2. Littératie en santé des patients avec un cancer - Étude nationale multicentrique LICAPA
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L. Hue, M. Pulido, E. Paillaud, A. Galvin, P. Soubeyran, C. Lalet, S. Doublet, and S. Mathoulin-Pelissier
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Epidemiology ,Public Health, Environmental and Occupational Health - Published
- 2023
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3. Littératie en santé : Étude nationale chez des patients avec un cancer (LICAPA)
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M. Pulido, E. Paillaud, A. Galvin, P. Soubeyran, C. Lalet, S. Doublet, L. Hue, and S. Mathoulin-pelissier
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Epidemiology ,Public Health, Environmental and Occupational Health - Published
- 2022
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4. Silicon photomultipliers as readout for a segmented Time-of-Flight plastic detector
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H. Schaffner, S. Saha, J. Vesic, P. Bednarczyk, J. Gerl, M. Reese, M. Górska, S. Doublet, F. Ameil, M. L. Cortés, Norbert Pietralla, École Centrale de Lyon (ECL), and Université de Lyon
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Nuclear and High Energy Physics ,Ion beam ,Physics::Instrumentation and Detectors ,STRIPS ,Scintillator ,Silicon photomultiplier ,01 natural sciences ,Time-of-flight measurement ,Particle identification ,law.invention ,law ,0103 physical sciences ,[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det] ,010306 general physics ,Instrumentation ,Heavy-ion detection ,Physics ,Plastic scintillator ,010308 nuclear & particles physics ,business.industry ,Detector ,Time resolution ,Time of flight ,Optoelectronics ,business ,Beam (structure) - Abstract
International audience; Particle identification at radioactive ion beam facilities requires Time-of-Flight detectors with an optimal time resolution and high rate capability. Segmented plastic scintillators are a common option for such detectors. A promising approach to cope with the high segmentation of modern devices is the use of silicon photomultipliers (SiPMs) as readout of the Time-of-Flight detectors. A prototype device consisting of strips of plastic scintillator of 4.4 × 100 × 1 mm 3 readout at both ends by SiPMs of two different sizes was tested using a 124 Xe beam at 600 MeV/nucleon. Timing and time-over-threshold information were extracted. The time resolution of the prototype was found to vary with the applied voltage and the SiPM size. After optimizing the voltage, resolutions of 14.3(10) ps and 10.4(1) ps were obtained for SiPMs of 1 × 1 mm 2 and 3 × 3 mm 2 respectively. These results point to SiPMs being suitable as readout of plastic scintillators at radioactive ion beam facilities.
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- 2018
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5. Conservation agriculture effects and policy support to mitigate soil degradation in Midi-Pyrénées (France)
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P. Pointereau, S. Doublet, P. Prosperi, J. M. Terres, and Sustainable Agriculture and Natural Resource Management (SANREM) Knowledgebase
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Conservation agriculture ,Soil Science ,Public policy ,Development ,Farm/Enterprise Scale Field Scale Governance ,Soil degradation ,Soil quality ,Soil retrogression and degradation ,Soil governance ,Environmental Chemistry ,Soil legislation ,Groundwater ,Policy framework ,Environmental planning ,General Environmental Science ,Government policy ,Midi-pyrénées ,business.industry ,Ecology ,Local policy ,Water quality ,Agriculture ,Soil erosion ,Land degradation ,France ,Business ,Soil conservation - Abstract
This paper draws on the results of a case study within the SoCo project and aims to assess the benefits and constraints in the application of conservation agriculture (CA) methods in Midi-Pyrenees, France, along with an evaluation of the coherence of the policy framework designed to improve the protection of soil resources. Inappropriate agricultural practices, under particular climate, terrain and soil conditions, have contributed to make erosion the main soil degradation phenomenon in Midi-Pyrenees, particularly under spring crops. The decrease of carbon stock is also a relevant issue. Among the various techniques applied by local farmers to reduce the impact of soil degradation on their land, CA appeared popular and was therefore analysed in detail. No specific legislation on soil protection is currently available in France, while the present agri-environmental policy, including the Rural Development Plan and the cross compliance measures, focuses mainly on water quality and biodiversity. A mixed methodological approach was used consisting of a literature review on the status of soils, of the characteristics of CA practices and of the soil-related policies in force. Semi-structured interviews with selected stakeholders on the use of soil conservation techniques and on soil legislation allowed a broader discussion of the study results. The research suggests that CA can effectively contribute to mitigate soil degradation in Midi-Pyrenees, although some implementation drawbacks seem to limit its wider use mainly due to lack of a specific support. Therefore, a better targeting of existing policies would be desirable for an improved protection of soil resources. Copyright © 2010 John Wiley & Sons, Ltd.
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- 2011
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6. Behaviour of NiAl APS‐coatings in chlorine‐containing atmospheres
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Michael Schütze, Till Weber, G. Tegeder, Hadj Latreche, Patrick J. Masset, Gerhard K. Wolf, and S. Doublet
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Nial ,Materials science ,Mechanical Engineering ,Metallurgy ,Metals and Alloys ,Evaporation ,chemistry.chemical_element ,General Medicine ,engineering.material ,Surfaces, Coatings and Films ,Corrosion ,Nickel ,Coating ,chemistry ,Mechanics of Materials ,Aluminium ,Materials Chemistry ,engineering ,Chlorine ,Environmental Chemistry ,Thermal spraying ,computer ,computer.programming_language - Abstract
Due to their thermal expansion coefficient being close to those of ferritic steels, NiAl atmospheric plasma spraying (APS)-coatings have been chosen to be tested in chloridizing atmosphere. A new type of quasi-stability diagram which couples thermodynamic and kinetic approaches was developed to define the stability domains of the pure metals aluminium and nickel in dynamic chlorine- and oxygen-containing atmospheres. NiAl APS-coatings (300 µm) with low porosity on steels were applied and tested in an atmosphere containing 0.2 v/o chlorine and 3 ppm oxygen. After 280 h of exposure one quarter of the outer coating was transformed into a protective alumina layer. Much nickel depletion, due to the evaporation of nickel chlorides, was observed.
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- 2008
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7. Tectonostratigraphic Evolution of the Outboard North Congo and South Gabon Basins and its Implication on Pre-salt Play
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A.K. Upadhyay, S. Doublet, and F.S. Mustapha
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Paleontology ,Hinge line ,Sequence (geology) ,Tectonics ,Geography ,Rift ,Stratigraphy ,Magmatism ,Sedimentary rock ,Palaeogeography - Abstract
Summary The North Congo and South Gabon basins are divided into the inboard and outboard sub-basins by the Atlantic Hinge Line, which was formed in the Hauterivian (133 – 120 Ma) during the second phase of rifting. This structural segmentation directly controls the play distributions in the basins and over the past 60 years, the inboard sub-basin has been heavily explored for hydrocarbon accumulations in the post-salt and pre-salt sequences. The pre-salt sequence in the outboard sub-basin remains underexplored and as a result, is poorly understood. The purpose of this study is to (1) understand the tectonic framework and evolutionary history of the margin and outboard sub-basin, (2) investigate the relationship between tectonics and sedimentation in the outboard sub-basin, (3) identify the implications of this evolution on the pre-salt exploration. Our preliminary results show that (1) there is a northward change in rifting and structuration style along the West Africa margin as implied by our 2D deep reflection seismic, (2) the early rift sedimentary sequences are confined in the inboard sub-basin whereas the late rift sequence is prominently thicker in the outboard sub-basin.
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- 2016
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8. Climagri® : un outil et une démarche pour co-construire des stratégies territoriales d’atténuation des émissions de polluants atmosphériques et de gaz à effet de serre d’origine agricole sur les territoires
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A. Trévisiol, L. Galsomiès, J. Mousset, S. Martin, Thomas Eglin, S. Doublet, and E. Martin
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Atmospheric Science ,Political science ,Forestry ,Pollution - Abstract
La reduction des emissions de polluants atmospheriques et de gaz a effet de serre (GES) d’origine agricole constitue un enjeu majeur pour l’atteinte des objectifs nationaux, actuels et futurs, d’amelioration de la qualite de l’air et de contribution a l’attenuation du changement climatique. L’echelle des territoires est un maillon interessant pour le portage de projets et la mobilisation d’acteurs locaux de maniere transversale. L’outil ClimAgri®, porte par l’ADEME, permet d’effectuer un diagnostic des emissions de plusieurs polluants atmospheriques (en particulier l’ammoniac), de gaz a effet de serre, des consommations d’energie de l’agriculture et la foret, a l’echelle d’un territoire, au regard de son potentiel nourricier et de production de biomasse. Ce diagnostic constitue un support pour identifier les principaux enjeux et les leviers d’actions, notamment dans le cadre des Plans Climat Air Energie Territoriaux (PCAET). Sa mise en œuvre s’accompagne d’une demarche de projet, visant a partager ces elements avec les acteurs du territoire et a co-construire un plan d’actions concret pour favoriser le deploiement de pratiques agricoles vertueuses, adaptees aux contextes locaux. En 2015, l’outil Climagri® a notamment ete utilise au niveau national dans le cadre d’exercices de scenarisation prospective a l’horizon 2035 : les « scenarios prospectifs climat-air energie » conduits par le ministere en charge de l’energie et la mise a jour du volet agricole de la vision energetique de l’ADEME. Il a permis d’animer l’elaboration de scenarios pour le secteur agricole francais sur la base d’hypotheses d’evolution couplees entre elles et credibles.
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- 2016
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9. Health literacy and the use of digital tools in older patients with cancer and their younger counterparts: A multicenter, nationwide study.
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Paillaud E, Galvin A, Doublet S, Poisson J, Gay P, Perrin C, Boudou-Rouquette P, Grellety T, Teyssonneau D, Ayati S, Saint-Lezer A, Culine S, Annonay M, Solem-Laviec H, Boulahssass R, Baldini C, Tchalla A, Lalet C, Hue L, Pulido M, and Mathoulin-Pélissier S
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- Humans, Cross-Sectional Studies, Female, Middle Aged, Male, Adult, France, Aged, Surveys and Questionnaires, Adolescent, Age Factors, Young Adult, Internet, Health Literacy, Neoplasms
- Abstract
Objectives: To evaluate health literacy (HL), assess the use of digital tools/sources, and identify factors associated with low or moderate HL in older (aged ≥65) and younger (18-64) patients with cancer., Methods: A cross-sectional multicenter study including patients with cancer was conducted in 26 centers in France. HL was assessed using the Functional, Communicative and Critical Health Literacy (FCCHL) scale. Factors associated with low/moderate HL (score
- Published
- 2025
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10. Systemic treatment among frail older patients with cancer: An observational cohort.
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Doublet S, Pagès A, Thomas ZA, Beraud-Chaulet G, Valery M, Naoun N, Canoui-Poitrine F, Nagera-Lazarovici C, Baldini C, and Frélaut M
- Abstract
Introduction: In the past, certain oncological therapies were not offered to frail older patients. However, the advancement of geriatric oncology, tailored chemotherapy regimens, the introduction of new treatments, and the optimization of supportive care have contributed to enhancing the therapeutic margin. We aimed to evaluate the benefit of systemic treatment among older adults by assessing the three-month survival of older frail patients with metastatic cancer., Materials and Methods: This retrospective cohort study included patients aged 70 and over with metastatic cancer who underwent pre-therapeutic geriatric assessment at Gustave Roussy Hospital between May 2020 and May 2022 and were categorized as "frail" according to the SIOG-1 classification, whether they received systemic treatment (ST group) or exclusive supportive care (SC group)., Results: The ST group included 77 patients, and the SC group included 44 patients. Patients in the ST group had a median age of 80.6 years (82.7 years in SC group). The three-month overall survival rate was 81.8 % [95 % Confidence Interval (CI) 71.8; 88.9] in the ST group. The median survival rate was 10.6 months [95 % CI 6.3; 12.6] in the ST group. In multivariate analysis within the ST group, loss of autonomy assessed by activity of daily living (ADL) (HR 2.16 [1.09; 4.28]) and more frailty factors (HR 1.40 [1.01; 1.95]) were associated with lower three-month survival., Discussion: Older frail patients with metastatic cancer may benefit from systemic oncologic treatment. The introduction of such treatment for patients with loss of autonomy in ADL or cumulative frailty factors should be considered only with caution., Competing Interests: Declaration of Competing Interest Marine Valery reports receiving a fee from Merck for participation on its Advisory Board. Capucine Baldini is principal/sub-Investigator of Clinical Trials for Abbvie, Agios Pharmaceuticals, Amgen, Argen-X Bvba, Arno Therapeutics, Astex Pharmaceuticals, Astra Zeneca, Aveo, Bayer Healthcare Ag, Bbb Technologies Bv, Blueprint Medicines, Boehringer Ingelheim, Bristol Myers Squibb, Celgene Corporation, Chugai Pharmaceutical Co., Clovis Oncology, Daiichi Sankyo, Debiopharm S.A., Eisai, Eli Lilly, Exelixis, Forma, Gamamabs, Genentech, Inc., Glaxosmithkline, H3 Biomedicine, Inc., Hoffmann La Roche Ag, Innate Pharma, Iris Servier, Janssen Cilag, Kyowa Kirin Pharm. Dev., Inc., Loxo Oncology, Lytix Biopharma As, Medimmune, Menarini Ricerche, Merck Sharp & Dohme Chibret, Merrimack Pharmaceuticals, Merus, Millennium Pharmaceuticals, Nanobiotix, Nektar Therapeutics, Novartis Pharma, Octimet Oncology Nv, Oncoethix, Onyx Therapeutics, Orion Pharma, Oryzon Genomics, Pfizer, Pharma Mar, Pierre Fabre, Roche, Sanofi Aventis, Taiho Pharma, Tesaro, Inc., Xencor; benefits from research grants from BMS; reports non-financial support (drug supplied) from Astrazeneca, Bayer, BMS, Boringher Ingelheim, Johnson & Johnson, Lilly, Medimmune, Merck, NH TherAGuiX, Pfizer, Roche; reports consulting from Bicycle therapeutics, Rising Tide Foundation, ITEOS, Boxer Capital, JM; reports honoraria from GSK, BMS, AZ, Amgen, Sanofi, MSD Janssen for travel accommodation; reports funding from BMS Foundation. Maxime Frélaut reports receiving a fee from Sandoz for participation on its Advisory Board, a fee as an invited speaker from MSD, and an institutional research grant from IPSEN. The other authors indicated they did not have any financial relationships., (Copyright © 2024 Elsevier Ltd. All rights reserved.)
- Published
- 2024
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11. Effect of face familiarity on age decision.
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Bruyer R, Mejias S, and Doublet S
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- Analysis of Variance, Female, Humans, Male, Reaction Time physiology, Semantics, Students psychology, Task Performance and Analysis, Visual Perception physiology, Aging psychology, Decision Making physiology, Face, Recognition, Psychology physiology
- Abstract
The present experiment was planned to check whether the extraction of apparent age is affected by face identity (familiarity) or not. According to the traditional view, age estimation should be carried out independently of face identity, because it is one of the visually derived semantic codes (like gender and ethnicity). However, little is known about its underlying mechanisms. Moreover, some recent studies have cast doubt on the parallel thesis regarding facial expression, facial speech, ethnicity, and gender. Given the promising results of a pilot experiment (n=24), 16 Caucasian participants were enrolled in an "age decision" task on morphed faces derived from one old and one young source-face, in the proportion 70:30. The respondents had previously been familiarised with half the source faces by a learning procedure (associating the face, surname, occupation and city of residence of the person displayed), while the remaining half were unfamiliar. The results showed that age decision was affected by face familiarity, at least when the task was perceptually difficult enough. This adds support to the thesis that the identification of identity and the extraction of visually derived semantic codes are not made independently from each other. The status of age, within the visually derived semantic codes, is also discussed.
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- 2007
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