198 results on '"S. De Stefani"'
Search Results
2. Penile Fracture and Associated Urethral Injury
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S. De Stefani, R. Stubinski, F. Ferneti, A. Simonato, and G. Carmignani
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Technology ,Medicine ,Science - Published
- 2004
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3. Microlaparoscopy in Sex Reassignment Surgery
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S. De Stefani, C. Trombetta, M. Raber, G. Savaco, U. Moro, and E. Belgrano
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Technology ,Medicine ,Science - Abstract
Sex reassignment (male to female surgery) is a standard operation which is aimed at constructing female genitalia and obtaining a cosmetic and functional result that is similar to that of a normal female subject. The ideal surgical procedure has not yet been described, but the various techniques which have been proposed in the literature are similar. The most cumbersome maneuver of the procedure is that of creating a neovaginal cavity inside the perineum. This step is generally carried out by means of blunt dissection between the rectal wall and the prostate, but most of the surgery is blindly performed without visual control. In these conditions, the risk of rectal injury is high, and may lead to severe intraoperative complications. Microlaparoscopy allows for a direct observation of the perineal dissection from inside the peritoneal cavity, thus avoiding risk of rectal injury. The technique is simple to perform, is non-invasive, and only 15 minutes are added to the operation.
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- 2004
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4. Reconstruction of the bulbar urethra using dorsal onlay buccal mucosal grafts: New concepts and surgical tricks
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Guido Barbagli and S De Stefani
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Bulbar urethral ,buccal mucosa ,fibrin glue ,graft ,urethral reconstruction ,urethroplasty ,Diseases of the genitourinary system. Urology ,RC870-923 - Abstract
Buccal mucosa onlay graft urethroplasty represents one of the most widespread methods for the repair of strictures in the bulbar urethra, because of its thick and highly vascular spongiosum tissue. Recently the location of the patch has become a contentious issue, since we described our original techniques of dorsal onlay graft urethroplasty. The design rationale for this approach was based on the concept that the corporeal body remains a healthy host for receiving a free transplanted tissues. Moreover, graft fixation onto a defined surface may decrease graft shrinkage and sacculation. The success rate using buccal mucosa grafts for the repair of bulbar urethral strictures has generally been high with dorsal or ventral onlay grafts or using an augmented roof-strip anastomotic urethroplasty. We describe here the fundamental concepts of the bulbar urethra reconstruction using buccal mucosal grafts, presenting a new surgical technique of dorsal onlay buccal mucosa graft urethroplasty using fibrin glue.
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- 2006
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5. Reproductive (epi)genetics
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C. Lynch, N. Tee, H. Rouse, A. Gordon, L. Sati, C. Zeiss, B. Soygur, I. Bassorgun, E. Goksu, R. Demir, J. McGrath, M. L. Groendahl, L. Thuesen, A. N. Andersen, A. Loft, J. Smitz, T. Adriaenssens, J. Vikesa, R. Borup, E. Mersy, N. Kisters, M. V. E. Macville, J. J. M. Engelen, S.-E. N. N. Consortium, P. P. C. A. Menheere, J. P. Geraedts, A. B. C. Coumans, S. G. M. Frints, T. Aledani, S. Assou, S. Traver, O. Ait-ahmed, H. Dechaud, S. Hamamah, E. Mizutani, N. Suzumori, C. Sugiyama, Y. Hattori, T. Sato, H. Ando, Y. Ozaki, M. Sugiura-Ogasawara, M. Wissing, S. G. Kristensen, C. Y. Andersen, A. L. Mikkelsen, T. Hoest, A. Velthut-Meikas, J. Simm, M. Metsis, A. Salumets, S. Palini, L. Galluzzi, S. De Stefani, M. Primiterra, D. Wells, M. Magnani, C. Bulletti, P. H. Vogt, P. Frank-Herrmann, U. Bender, T. Strowitzki, B. Besikoglu, P. Heidemann, L. Wunsch, M. Bettendorf, L. Jelinkova, S. Vilimova, M. Kosarova, P. Sebek, E. Volemanova, M. Kruzelova, J. Civisova, L. Svobodova, V. Sobotka, T. Mardesic, C. van de Werken, M. A. Santos, C. Eleveld, J. S. E. Laven, E. B. Baart, L. Y. Pylyp, L. A. Spinenko, V. D. Zukin, J. Perez-Sanz, R. Matorras, J. Arluzea, J. Bilbao, N. Gonzalez-Santiago, N. Yeh, A. Koff, A. Barlas, Y. Romin, K. Manova-Todorova, C. D. l. Hoz, A. L. Mauri, A. M. Nascimento, L. D. Vagnini, C. G. Petersen, J. Ricci, F. C. Massaro, M. Cavagna, A. Pontes, J. B. A. Oliveira, R. L. R. Baruffi, J. G. Franco, E. X. Wu, S. Ma, M. Parriego, M. Sole, M. Boada, B. Coroleu, A. Veiga, G. Kakourou, M. Poulou, C. Vrettou, A. Destouni, J. Traeger-Synodinos, E. Kanavakis, A. N. Yatsenko, A. P. Georgiadis, M. M. McGuire, M. Zorrilla, K. D. Bunce, D. Peters, A. Rajkovic, M. Olszewska, M. Kurpisz, A. Z. A. Gilbertson, C. S. Ottolini, M. C. Summers, K. Sage, A. H. Handyside, A. R. Thornhill, D. K. Griffin, M. K. Chung, J. W. Kim, J. H. Lee, H. J. Jeong, M. H. Kim, M. J. Ryu, S. J. Park, H. Y. Kang, H. S. Lee, B. Zimmermann, M. Banjevic, M. Hill, P. Lacroute, M. Dodd, S. Sigurjonsson, P. Lau, D. Prosen, N. Chopra, A. Ryan, M. Hall, S. McAdoo, Z. Demko, B. Levy, M. Rabinowitz, A. Vereczeky, Z. S. Kosa, S. Savay, M. Csenki, L. Nanassy, B. Dudas, Z. S. Domotor, D. Debreceni, A. Rossi, J. R. Alegretti, J. Cuzzi, M. Bonavita, M. Tanada, P. Matunaga, P. Fettback, M. B. Rosa, V. Maia, P. Hassun, E. L. A. Motta, M. Piccolomini, C. Gomes, B. Barros, M. Nicoliello, T. Criscuolo, E. Miyadahira, D. Montjean, M. Benkhalifa, I. Berthaut, J. F. Griveau, K. Morcel, A. Bashamboo, K. McElreavey, C. Ravel, C. Rubio, L. Rodrigo, E. Mateu, A. Mercader, V. Peinado, P. Buendia, M. Milan, A. Delgado, N. Al-Asmar, L. Escrich, I. Campos-Galindo, S. Garcia-Herrero, M. E. Poo, P. Mir, C. Simon, A. Reyes-Engel, M. Cortes-Rodriguez, A. Lendinez, B. Perez-Nevot, A. R. Palomares, M. R. Galdon, A. Ruberti, M. G. Minasi, A. Biricik, A. Colasante, D. Zavaglia, E. Iammarrone, F. Fiorentino, E. Greco, N. Demir, S. Ozturk, B. Sozen, R. Morales, B. Lledo, J. A. Ortiz, J. Ten, J. Llacer, R. Bernabeu, M. Nagayoshi, A. Tanaka, I. Tanaka, H. Kusunoki, S. Watanabe, S. G. Temel, C. Beyazyurek, G. C. Ekmekci, F. Aybar, C. Cinar, S. Kahraman, S. Nordqvist, K. Karehed, H. Akerud, M. Gultomruk, P. Tulay, N. Findikli, E. Yagmur, G. Karlikaya, U. Ulug, M. Bahceci, M. F. Bargallo, M. R. Arevalo, M. M. Salat, I. V. Barbat, J. T. Lopez, M. E. Algam, A. B. Boluda, G. C. de Oya, E. N. Tolmacheva, A. A. Kashevarova, N. A. Skryabin, I. N. Lebedev, E. Semaco, A. Belo, M. Riboldi, L. Luz, N. Nobrega, R. Mazetto, J. A. Alegretti, M. Bibancos, P. Serafini, J. Neupane, M. Vandewoestyne, B. Heindryckx, T. Deroo, Y. Lu, S. Ghimire, S. Lierman, C. Qian, D. Deforce, P. De Sutter, T. Viloria, J. M. Martinez-Jabaloyas, M. Gil-Salom, A. Capalbo, N. Treff, D. Cimadomo, X. Tao, K. Ferry, F. M. Ubaldi, L. Rienzi, R. T. Scott, N. Katzorke, H. P. Vogt, A. Hehr, C. Gassner, B. Paulmann, Z. Kowalzyk, M. Klatt, S. Krauss, D. Seifert, B. Seifert, U. Hehr, M. Lobascio, M. T. Varricchio, P. Rubino, S. Bono, R. P. Cotarelo, L. Spizzichino, A. Colicchia, P. Giannini, M. Suhorutshenko, and K. Rosenstein-Tamm
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Genetics ,Reproductive Medicine ,Rehabilitation ,Obstetrics and Gynecology ,Biology - Published
- 2013
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6. Genomic DNA in human blastocoele fluid
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Carlo Bulletti, S. De Stefani, Dagan Wells, Mauro Magnani, Luca Galluzzi, Marzia Bianchi, Simone Palini, Carlo, Bulletti, Simone, Palini, Luca, Galluzzi, Silvia, De Stefani, M. Bianchi, Dagan, Well, and Mauro, Magnani
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Comparative Genomic Hybridization ,Spectrometry, Mass, Electrospray Ionization ,Base Sequence ,Genome, Human ,Obstetrics and Gynecology ,Embryo ,DNA ,Biology ,Embryo, Mammalian ,Real-Time Polymerase Chain Reaction ,Y chromosome ,Molecular biology ,Cell biology ,Chromosome 17 (human) ,genomic DNA ,Real-time polymerase chain reaction ,Reproductive Medicine ,Embryo cryopreservation ,Humans ,Vitrification ,Base Sequence Chromatography, High Pressure Liquid Comparative Genomic Hybridization DNA/genetics DNA/isolation & purification* DNA Primers Embryo, Mammalian* Genome, Human* Humans Real-Time Polymerase Chain Reaction Spectrometry, Mass, Electrospray Ionization ,Chromatography, High Pressure Liquid ,DNA Primers ,Developmental Biology ,Comparative genomic hybridization - Abstract
Reprod Biomed Online. 2013 Jun;26(6):603-10. doi: 10.1016/j.rbmo.2013.02.012. Epub 2013 Mar 13. Genomic DNA in human blastocoele fluid. Palini S1, Galluzzi L, De Stefani S, Bianchi M, Wells D, Magnani M, Bulletti C. Author information Abstract IVF often requires embryo cryopreservation through vitrification. During the vitrification process, the embryos can be collapsed by withdrawing the blastocoele fluid. The metabolomic profile of blastocoele fluid has been recently investigated by high-performance liquid chromatography-electrospray ionization-mass spectrometry to provide metabolite information that can help estimations of implantation efficiency. However, the presence of embryo DNA in blastocoele fluid has not been reported to date. This study shows using real-time PCR that genomic DNA was present in about 90% of blastocoele fluid samples harvested during the vitrification procedure. Moreover, the potential for determining embryo sex directly from blastocoele fluid is demonstrated by amplifying the multicopy genes TSPY1 (on the Y chromosome) and TBC1D3 (on chromosome 17). This opens up the possibility of screening embryos from couples carrying an X-linked disorder to identify male embryos at high risk of disease. The application of whole-genome amplification technologies to fluid samples is also shown to be feasible, potentially allowing more comprehensive genetic tests. As proof of principle, microarray comparative genomic hybridization was attempted to confirm the sex of embryos as well as detect several aneuploidies. However, further studies are needed to validate this approach and confirm that the accuracy is sufficient for diagnostic purposes.
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- 2016
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7. Elective segmental ureterectomy for transitional cell carcinoma of the ureter: long-term follow-up in a series of 73 patients
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Andrea Gregori, Andrea Lissiani, Emanuele Belgrano, Giampaolo Bianchi, Sara Benvenuto, M. Ennas, F. Gaboardi, Giampaolo Siena, Andrea Benelli, Marco Carini, S. De Stefani, Mauro Gacci, Alchiede Simonato, G. Carmignani, M. Rosso, and Virginia Varca
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medicine.medical_specialty ,medicine.diagnostic_test ,Ureterectomy ,business.industry ,Urology ,Anastomosis ,urologic and male genital diseases ,medicine.disease ,Surgery ,Transitional cell carcinoma ,Ureter ,medicine.anatomical_structure ,Carcinoma ,medicine ,Ureteroscopy ,business ,Survival rate ,Ureteral neoplasm - Abstract
Study Type – Therapy (outcome) Level of Evidence 2b What's known on the subject? and What does the study add? Upper Urinary Tract (UUT) Transitional Cell Carcinoma (TCC) is an uncommon disease and represents approximately 5% of all urothelial carcinomas. We report our series on 73 patients treated with Kidney Sparing Surgery for UUT TCC. Good results have been achieved in terms of oncological outcome comparing this conservative approach to the radical nephrourectomy. OBJECTIVES • To report the long-term oncological outcome in patients with transitional cell carcinoma of the ureter electively treated with kidney-sparing surgery. • To compare our data with the few series reported in the literature. PATIENTS AND METHODS • We considered 73 patients with transitional cell carcinoma of the distal ureter treated in five Italian Departments of Urology. • The following surgeries were carried out: 38 reimplantations on psoas hitch bladder (52%), 21 end-to-end anastomoses (28.8%), 11 direct ureterocystoneostomies (15.1%) and three reimplantations on Boari flap bladder (4.1%). • The median follow-up was 87 months. RESULTS • Tumours were pTa in 42.5% of patients, pT1 in 31.5%, pT2 in 17.8% and pT3 in 8.2%. • Recurrence of bladder urothelial carcinoma was found in 10 patients (13.7%) after a median time of 28 months. • The bladder recurrence-free survival at 5 years was 82.2%. • The overall survival at 5 years was 85.3% and the cancer-specific survival rate at 5 years was 94.1%. CONCLUSION • Our data show that segmental ureterectomy procedures do not result in worse cancer control compared with data in the literature regarding nephroureterectomy.
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- 2012
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8. SELECTED ORAL COMMUNICATION SESSION, SESSION 70: ANDROLOGY AND SEMINAL FACTORS Wednesday 6 July 2011 14:00 - 15:45
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Simone Palini, Maria Chiara Tagliamonte, T. Milachich, Emanuele Pelosi, Marcos Meseguer, S. García-Herrero, J. Múgica, L. Romany, C. Braña Pelayo, Antonia Expósito, Lorena Crisol, S. Fernandez Shaw, A. Shterev, P. Caballero Peregrin, Susana Cortes, Carlo Bulletti, L. Donati, S. De Stefani, S. Kyurkchiev, E. G. J. M. Arts, A. Tiezzi, José A. Horcajadas, Serena Benedetti, I. Pons Mallol, Beatriz Corcóstegui, L. Ortega, V. Polli, Antonio Pellicer, Nicolás Garrido, J. van Echten-Arends, P. Rocchi, N.E Wester, Jolande A. Land, R. Cercas Duque, C. Villas Martin, Mariangela Primiterra, Simona Catalani, Roberto Matorras, José Antonio Martínez-Conejero, D. Dyulgerova-Nikolova, J.A Guijarro, V. Scala, M. Ruiz, Jaime Gosálvez, Rocio Nunez-Calonge, Franco Canestrari, Henk Groen, and Olga Ramón
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Gynecology ,endocrine system ,Pregnancy ,medicine.medical_specialty ,medicine.diagnostic_test ,urogenital system ,business.industry ,media_common.quotation_subject ,Rehabilitation ,Obstetrics and Gynecology ,Unprotected intercourse ,Fertility ,Semen analysis ,medicine.disease ,Predictive value ,Sperm ,Reproductive Medicine ,medicine ,Sperm morphology ,Session (computer science) ,business ,reproductive and urinary physiology ,media_common - Abstract
Introduction: Couples who have not achieved a pregnancy within one year of unprotected intercourse qualify for a fertility work-up. A semen analysis is part of this work-up and includes the assessment of sperm concentration, motility and morphology. The predictive value of sperm morphology has been
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- 2011
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9. POSTER VIEWING SESSION - EMBRYOLOGY
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S. Fourati Ben Mustapha, M. Khrouf, K. Kacem Ben Rejeb, H. Elloumi Chaabene, G. Merdassi, D. Wahbi, M. Ben Meftah, F. Zhioua, A. Zhioua, A. Azzarello, T. Host, A. L. Mikkelsen, C. P. Theofanakis, V. Dinopoulou, D. Mavrogianni, G. A. Partsinevelos, P. Drakakis, K. Stefanidis, A. Bletsa, D. Loutradis, L. Rienzi, A. Cobo, A. Paffoni, C. Scarduelli, A. Capalbo, N. Garrido, J. Remohi, G. Ragni, F. M. Ubaldi, R. Herrer, M. Quera, E. GIL, J. Serna, M. L. Grondahl, J. Bogstad, I. E. Agerholm, J. G. Lemmen, U. Bentin-Ley, P. Lundstrom, U. S. Kesmodel, M. Raaschou-Jensen, S. Ladelund, L. Guzman, C. Ortega, F. K. Albuz, R. B. Gilchrist, P. Devroey, J. Smitz, M. De Vos, M. Bielanska, M. C. Leveille, E. Borghi, M. C. Magli, M. J. Figueroa, G. Mascaretti, A. P. Ferraretti, L. Gianaroli, E. Szlit, F. Leocata Nieto, G. Maggiotto, G. Arenas, N. Tarducci Bonfiglio, A. Ahumada, R. Asch, R. Sciorio, N. Dayoub, J. Thong, S. Pickering, J. Ten, M. A. Carracedo, J. Guerrero, A. Rodriguez-Arnedo, J. Llacer, R. Bernabeu, C. Tatone, T. Heizenrieder, G. Di Emidio, P. Treffon, T. Seidel, U. Eichenlaub-Ritter, S. S. Cortezzi, E. C. Cabral, C. R. Ferreira, M. G. Trevisan, R. C. S. Figueira, D. P. A. F. Braga, M. N. Eberlin, A. Iaconelli Jr., E. Borges Jr., A. Zabala, T. Pessino, L. Blanco, G. Rey Valzacchi, F. Leocata, F. Vanden Meerschaut, B. Heindryckx, C. Qian, D. Deforce, L. Leybaert, P. De Sutter, M. De las Heras, J. L. De Pablo, B. Navarro, J. A. Agirregoikoa, G. Barrenetxea, M. Cruz, I. Perez-Cano, B. Gadea, J. Herrero, M. Martinez, M. Roldan, M. Munoz, A. Pellicer, M. Meseguer, N. Galindo, F. Scarselli, E. Alviggi, A. Colasante, M. G. Minasi, P. Rubino, M. Lobascio, S. Ferrero, K. Litwicka, M. T. Varricchio, P. Giannini, P. Piscitelli, G. Franco, D. Zavaglia, Z. P. Nagy, E. Greco, F. Urner, D. Wirthner, F. Murisier, P. Mock, M. Germond, B. Amorocho Llanos, G. Calderon, D. Lopez, L. Fernandez, M. Nicolas, J. Landeras, S. L. Finn-Sell, R. Leandri, T. P. Fleming, N. S. Macklon, Y. C. Cheong, J. J. Eckert, J. H. Lee, Y. J. Jung, H. K. Hwang, A. Kang, S. J. An, J. Y. Jung, H. C. Kwon, S. J. Lee, S. Palini, L. Zolla, S. De Stefani, V. Scala, A. D'Alessandro, V. Polli, P. Rocchi, A. Tiezzi, E. Pelosi, L. Dusi, C. Bulletti, R. Fadini, M. Lain, M. Mignini Renzini, F. Brambillasca, G. Coticchio, M. Merola, M. C. Guglielmo, M. Dal Canto, R. Figueira, A. S. Setti, K. C. Worrilow, C. D. Uzochukwu, S. Eid, S. Le Gac, T. C. Esteves, F. van Rossem, A. van den Berg, M. Boiani, E. Kasapi, Y. Panagiotidis, M. Goudakou, A. Papatheodorou, T. Pasadaki, N. Prapas, Y. Prapas, P. Vanderzwalmen, S. Norasing, P. Atchajaroensatit, W. Tawiwong, O. Thepmanee, S. Saenlao, J. Aojanepong, P. Hunsajarupan, K. Sajjachareonpong, P. Punyatanasakchai, S. Maneepalviratn, U. Jetsawangsri, A. Tejera, I. Rubio, J. L. Romero, V. Nordhoff, S. Schlatt, A. N. Schuring, L. Kiesel, S. Kliesch, R. Azambuja, L. Okada, V. Lazzari, L. Dorfman, J. Michelon, M. Badalotti, F. Badalotti, A. Petracco, C. Schwarzer, K. Versieren, I. De Croo, S. Lierman, W. De Vos, E. Van den Abbeel, J. Gerris, I. Milacic, D. Borogovac, M. Veljkovic, B. Arsic, D. Jovic Bojovic, D. Lekic, D. Pavlovic, E. Garalejic, D. F. Albertini, E. De Ponti, F. Sanges, R. Talevi, L. Papini, V. Mollo, L. F. Rienzi, R. Gualtieri, C. Orteg, J. Choi, H. Lee, S. Ku, S. Kim, Y. Choi, J. Kim, S. Moon, E. Demilly, S. Assou, S. Moussaddykine, H. Dechaud, S. Hamamah, T. Takisawa, M. Doshida, H. Hattori, Y. Nakamura, T. Kyoya, Y. Shibuya, Y. Nakajo, A. Tasaka, M. Toya, K. Kyono, S. Novo, O. Penon, R. Gomez, L. Barrios, M. Duch, J. Santalo, J. Esteve, C. Nogues, J. A. Plaza, L. Perez-Garcia, E. Ibanez, S. Chavez, K. Loewke, B. Behr, R. Reijo Pera, S. Huang, H. Wang, Y. Soong, C. Chang, T. Okimura, M. Kuwayama, C. Mori, M. Morita, K. Uchiyama, F. Aono, K. Kato, Y. Takehara, O. Kato, M. Minasi, V. Casciani, L. Arizzi, C. Mencacci, C. Piscitelli, F. Cucinelli, A. Tocci, E. Wydooghe, L. Vandaele, J. Dewulf, A. Van Soom, J. H. Moon, W. Y. Son, A. Mahfoudh, S. Henderson, S. G. Jin, E. Shalom-Paz, M. Dahan, H. Holzer, K. Mahmoud, C. Triki-Hmam, K. Terras, T. Hfaiedh, M. H. Ben Aribia, H. Otsubo, A. Egashira, K. Tanaka, T. Matsuguma, M. Murakami, K. Murakami, M. Otsuka, N. Yoshioka, Y. Araki, T. Kuramoto, J. G. Smit, M. D. Sterrenburg, M. J. C. Eijkemans, H. G. Al-Inany, M. A. F. M. Youssef, F. J. M. Broekmans, K. Willoughby, L. DiPaolo, L. Deys, A. Lagunov, S. Amin, M. Faghih, E. Hughes, M. Karnis, F. Ashkar, W. A. King, M. S. Neal, I. Antonova, L. Veleva, L. Petkova, A. Shterev, C. Nogales, E. Martinez, M. Ariza, D. Cernuda, M. Gaytan, A. Linan, A. Guillen, F. Bronet, V. Cottin, D. Fabian, F. Allemann, A. Koller, J. C. Spira, D. Agudo, M. Martinez-Burgos, A. Arnanz, N. Basile, A. Rodriguez, Y. S. Cho, M. Filioli Uranio, B. Ambruosi, M. S. Paternoster, P. Totaro, A. M. Sardanelli, M. E. Dell'Aquila, U. Zollner, T. Hofmann, K. P. Zollner, B. Kovacic, P. Roglic, V. Vlaisavljevic, M. Sole, M. Boada, B. Coroleu, A. Veiga, G. Martiny, M. Molinari, A. Revelli, N. M. Chimote, M. Chimote, B. Mehta, N. N. Chimote, N. Sheikh, N. Nath, A. Mukherjee, K. Rakic, M. Reljic, H. J. Ingerslev, K. Kirkegaard, J. Hindkjaer, I. Agerholm, H. Kitasaka, N. Fukunaga, R. Nagai, T. Yoshimura, F. Tamura, K. Kitamura, N. Hasegawa, K. Nakayama, M. Katou, F. Itoi, E. Asano, N. Deguchi, K. Ooyama, Y. Hashiba, Y. Asada, M. Michaeli, N. Rotfarb, E. Karchovsky, O. Ruzov, R. Atamny, K. Slush, O. Fainaru, A. Ellenbogen, S. Chekuri, T. Chaisrisawatsuk, P. Chen, M. Pangestu, S. Jansen, S. Catt, E. Molinari, C. Racca, C. Ryu, S. Kang, J. Lee, D. Chung, S. Roh, H. Chi, Y. Yokota, M. Yokota, H. Yokota, S. Sato, M. Nakagawa, M. Komatsubara, M. Makita, K. Oyama, K. Naruse, S. Kilani, M. G. Chapman, M. Kwik, M. Chapman, S. Guven, E. Odaci, O. Yildirim, C. Kart, M. A. Unsal, E. Yulug, E. Isachenko, R. Maettner, E. Strehler, V. Isachenko, K. Hancke, R. Kreienberg, K. Sterzik, X. Y. Zheng, L. N. Wang, P. Liu, J. Qiao, F. Inoue, M. Dashtizad, H. Wahid, Y. Rosnina, M. Daliri, H. Hajarian, M. Akbarpour, O. Abbas Mazni, K. Knez, T. Tomaevic, E. Vrtacnik Bokal, B. Zorn, I. Virant Klun, M. Koster, J. Liebenthron, A. Nicolov, K. van der Ven, H. van der Ven, M. Montag, M. Fayazi, M. Salehnia, M. Beigi Boroujeni, B. Khansarinejad, K. Deignan, G. Emerson, E. Mocanu, J. J. Wang, M. Andonov, E. Linara, K. K. Ahuja, S. Nachef, F. F. Pasqualotto, E. Pasqualotto, C. C. Chang, D. P. Bernal, T. A. Elliott, D. B. Shapiro, A. A. Toledo, K. Economou, S. Davies, M. Argyrou, S. Doriza, P. Sisi, M. Moschopoulou, A. Karagianni, C. Mendorou, N. Polidoropoulos, C. Papanicopoulos, P. Stefanis, C. Karamalegos, H. Cazlaris, M. Koutsilieris, M. Mastrominas, S. Gotts, A. Doshi, J. Harper, P. Serhal, A. Borini, O. Guzeloglu-Kayisli, V. Bianchi, E. Seli, M. Lappi, M. A. Bonu, S. Mizuta, H. Hashimoto, Y. Kuroda, Y. Matsumoto, Y. Mizusawa, S. Ogata, S. Yamada, S. Kokeguchi, Y. Noda, M. Shiotani, M. Stojkovic, M. Ilic, N. Markovic, P. Stojkovic, G. Feng, B. Zhang, H. Zhou, L. Zhou, X. Gan, X. Qin, J. Shu, F. Wu, I. Molina Botella, E. Lazaro Ibanez, A. Debon Aucejo, J. Pertusa, P. J. Fernandez Colom, C. Li, Y. Zhang, Y. Cui, H. Zhao, J. Liu, J. B. A. Oliveira, C. G. Petersen, A. L. Mauri, F. C. Massaro, L. F. I. Silva, J. Ricci, M. Cavagna, A. Pontes, L. D. Vagnini, R. L. R. Baruffi, J. G. Franco Jr., V. Felipe, M. Vilela, M. Tiveron, C. Lombardi, M. I. Viglierchio, G. Marconi, V. Rawe, P. L. Wale, D. K. Gardner, K. Nakagawa, R. Sugiyama, Y. Nishi, Y. Kuribayashi, H. Jyuen, E. Yamashiro, A. Shirai, M. Inoue, O. Hovatta, V. Tohonen, J. Inzunza, L. Parmegiani, G. E. Cognigni, S. Bernardi, W. Ciampaglia, F. E. Infante, C. Tabarelli de Fatis, P. Pocognoli, A. Arnone, A. M. Maccarini, E. Troilo, M. Filicori, P. Radwan, I. Polac, M. Borowiecka, M. Bijak, and M. Radwan
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medicine.medical_specialty ,Reproductive Medicine ,Embryology ,Rehabilitation ,medicine ,Obstetrics and Gynecology ,Medical physics ,Session (computer science) ,Psychology - Published
- 2011
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10. Andrology (Male Fertility, Spermatogenesis)
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Y. Matsumoto, S. Goto, H. Hashimoto, S. Kokeguchi, M. Shiotani, H. Okada, P. Cohen - Bacrie, A. Hazout, S. Belloc, J. De Mouzon, Y. Menezo, M. Dumont, A. M. Junca, M. Cohen-Bacrie, S. Alvarez, F. Olivennes, N. Prisant, M. Weltin, W. Geissler, C. Clussmann, T. Strowitzki, W. Eggert-Kruse, Y. Endou, Y. Fjii, H. Motoyama, F. Q. Quintana, Z. L. Zaloa Larreategui, I. P. Iratxe Penalba, S. O. Sara Ortega, M. M. Monica Martin, G. Q. Guillermo Quea, J. S. Jose Serna, M. G. Showell, J. Brown, A. Yazdani, M. T. Stankiewicz, R. J. Hart, C. Zumoffen, M. J. Munuce, A. Caille, S. Ghersevich, A. M. Lendinez, B. Perez-Nevot, A. R. Palomares, A. Serrano Garballo, A. Rodriguez, A. Reche, A. Mayor-Olea, M. Ruiz-Galdon, A. Reyes-Engel, J. Mendiola, N. Jorgensen, A. M. Andersson, A. M. Calafat, J. B. Redmon, E. Z. Drobnis, C. Wang, A. Sparks, S. W. Thurston, F. Liu, S. H. Swan, A. C. Tarasconi, B. V. Tarasconi, D. V. Tarasconi, E. M. V. Silva, Y. Fujii, I. Crha, J. Pribyl, P. Skladal, J. Zakova, P. Ventruba, M. Pohanka, G. De La Fuente, A. Pacheco, J. A. G. Velasco, A. Requena, A. Pacheco Castro, M. San Celestino Carchenilla, R. Salvanes, A. Arnanz, C. Balmori, A. Pellicer, J. A. Garcia-Velasco, T. Ishikawa, M. Fujisawa, S. Kranz, K. Hersemeyer, A. Hentrich, H. R. Tinneberg, L. Konrad, L. Simon, D. Lutton, J. McManus, S. E. M. Lewis, S. Rubio, P. Simon Sanjurjo, S. Lewis, J. Buzzi, A. Valcarcel, E. Lombardi, R. Oses, V. Rawe, E. Young, A. Magendzo, S. Lizama, G. Duque, A. Mackenna, A. Monqaut, C. Zavaleta, G. Lopez, R. Lafuente, M. Brassesco, R. Condorelli, S. La Vignera, S. La Rosa, N. Barone, E. Vicari, S. Bellanca, R. D'Agata, A. E. Calogero, M. Enciso, M. Iglesias, I. Galan, A. Gosalvez, J. Gosalvez, M. Curaba, J. Poels, A. Van Langendonckt, J. Donnez, C. Wyns, M. Garcez, M. Salvador, E. B. Pasqualotto, D. P. A. F. Braga, E. Borges, F. F. Pasqualotto, T. Aoki, R. C. S. Figueira, L. G. L. Maldonado, A. Iaconelli, R. Frassini, J. Mandelli, A. S. Setti, S. S. Cortezzi, M. Di Mauro, N. Burrello, J. Kashir, C. Jones, C. Young, M. Ruas, P. Grasa, K. Rietdorf, E. Heytens, B. Heindryckx, S. Y. Yoon, R. A. Fissore, C. M. Deane, D. Nikiforaki, S. T. Tee, P. de Sutter, J. Parrington, K. Coward, L. Visser, G. H. Westerveld, S. K. M. van Daalen, F. van der Veen, M. P. Lombardi, S. Repping, S. Cubillos, S. Sanchez, J. Pedraza, G. Charria, H. Aparicio, A. Gongora, F. Caldino, S. Cuneo, J. P. Ou, W. E. Zhao, Y. F. Liu, Y. W. Xu, C. Q. Zhou, N. Al-Asmar Pinar, V. Peinado, J. Gruhn, M. Susiarjo, M. Gil-Salom, J. M. Martinez-Jabaloyas, J. Remohi, C. Rubio, T. Hassold, N. Al-Asmar, L. Rodrigo, T. J. Hassold, M. Bungum, N. Forsell, A. Giwercman, I. Amiri, N. Sheikh, R. Najafi, M. Godarzi, M. Farimani, H. Makukh, M. Tyrkus, D. Zastavna, A. Nakonechnuy, S. S. Khayat, L. V. Schileiko, L. F. Kurilo, S. Garcia-Herrero, N. Garrido, J. A. Martinez-Conejero, L. Romany, M. Meseguer, B. Dorphin, M. Lefevre, C. Gout, P. Oger, C. Yazbeck, N. Rougier, S. De Stefani, V. Scala, S. Benedetti, M. C. Tagliamonte, E. Zavagnini, S. Palini, C. Bulletti, F. Canestrari, N. Subiran, F. M. Pinto, M. L. Candenas, E. Agirregoitia, J. Irazusta, E. M. Cha, J. H. Lee, I. H. Park, K. H. Lee, M. H. Kim, M. S. Jensen, C. Rebordosa, A. M. Thulstrup, G. Toft, H. T. Sorensen, J. P. Bonde, T. B. Henriksen, J. Olsen, L. Bosco, M. Speciale, M. Manno, N. Amireh, M. C. Roccheri, E. Cittadini, P. Wu, Y. M. Lee, H. W. Chen, C. R. Tzeng, J. Llacer, J. Ten, B. Lledo, A. Rodriguez-Arnedo, R. Morales, R. Bernabeu, A. Garcia-Peiro, J. Martinez-Heredia, M. Oliver-Bonet, J. Ribas, C. Abad, M. J. Amengual, J. Navarro, J. Benet, C. Moutou, N. Gardes, J. C. Nicod, N. Becker, M. P. Bailly, I. Galland, O. Pirello, C. Rongieres, C. Wittemer, S. Viville, W. Elmahaishi, B. Smith, A. Doshi, P. Serhal, J. C. Harper, C. Rennemeier, U. Kammerer, J. Dietl, P. Staib, K. Elgmati, M. Nomikos, M. Theodoridou, B. Calver, K. Swann, F. A. Lai, I. Georgiou, L. Lazaros, N. Xita, A. Kaponis, N. Plachouras, E. Hatzi, K. Zikopoulos, F. Ferfouri, P. Clement, D. Molina Gomes, M. Albert, M. Bailly, R. Wainer, J. Selva, F. Vialard, T. Takisawa, K. Usui, T. Kyoya, Y. Shibuya, H. Hattori, Y. Sato, M. Ota, K. Kyono, P. C. Chiu, K. K. Lam, C. L. Lee, M. K. Chung, V. W. Huang, W. S. O, F. Tang, P. C. Ho, W. S. Yeung, C. H. Kim, J. Y. Lee, S. H. Kim, C. S. Suh, Y. K. Shin, Y. J. Kang, J. H. Jung, C. Y. Cha, E. S. Hwang, T. Mukaida, M. Nagaba, K. Takahashi, D. Elkaffash, M. Sedrak, I. Huhtaniemi, T. Abdel-Al, D. Younan, N. G. Cassuto, D. Bouret, I. Hammoud, Y. Barak, S. Seshadri, M. Bates, G. Vince, D. I. Jones, M. Ben Khalifa, D. Montjean, P. Cohen-Bacrie, F. X. Aubriot, M. Cohen, E. Boudjema, M. C. Magli, A. Crippa, B. Baccetti, A. P. Ferraretti, L. Gianaroli, T. Singer, Q. V. Neri, J. C. Hu, R. Maggiulli, Z. Kollman, E. Rauch, P. N. Schlegel, Z. Rosenwaks, G. D. Palermo, B. Zorn, B. Skrbinc, E. Matos, B. Golob, M. Pfeifer, J. Osredkar, E. Sabanegh, R. K. Sharma, A. Thiyagarajan, A. Agarwal, G. Robin, F. Boitrelle, F. Marcelli, C. Marchetti, V. Mitchell, D. Dewailly, J. M. Rigot, N. Rives, A. Perdrix, A. Travers, J. P. Milazzo, N. Mousset-Simeon, B. Mace, A. Jakab, Z. Molnar, M. Benyo, I. Levai, Z. Kassai, A. Ihan, A. Kopitar, M. Kolbezen, D. Vaamonde, M. E. Da Silva-Grigoletto, J. M. Garcia-Manso, R. Vaamonde-Lemos, S. C. Oehninger, G. Walis, D. Monahan, E. Ermolovich, E. Fadlon, A. Abu Elhija, M. Abu Elhija, E. Lunenfeld, M. Huleihel, M. Costantini-Ferrando, J. C. Y. Hu, J. G. Alvarez, E. Velilla, M. Lopez-Teijon, C. Lopez-Fernandez, H. G. Tempest, F. Sun, E. Ko, P. Turek, R. H. Martin, M. T. Zomeno-Abellan, A. Ramirez, A. Gutierrez-Adan, J. C. Martinez, J. Landeras, J. Ballesta, M. Aviles, M. Ganaiem, S. Binder, A. Meinhardt, L. Sousa, A. Grangeia, F. Carvalho, M. Sousa, A. Barros, C. Sifer, N. Sermondade, E. Hafhouf, C. Poncelet, B. Benzacken, R. Levy, J. P. Wolf, L. Crisol, F. Aspichueta, M. L. Hernandez, A. Exposito, R. Matorras, M. B. Ruiz-Larrea, J. I. Ruiz-Sanz, S. Jallad, F. Atig, H. Ben Amor, A. L. I. Saad, A. Kerkeni, M. Ajina, A. L. I. Othmane, I. Koscinski, L. Ladureau, F. Scarselli, V. Casciani, M. Lobascio, M. G. Minasi, P. Rubino, A. Colasante, L. Arizzi, K. Litwicka, E. Iammarrone, S. Ferrero, C. Mencacci, G. Franco, D. Zavaglia, Z. P. Nagy, E. Greco, S. Ohgi, M. Takahashi, C. Kishi, K. Suga, A. Yanaihara, L. W. Chamley, A. Wagner, and A. N. Shelling
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Andrology ,Reproductive Medicine ,Phospholipase C ,Point mutation ,Rehabilitation ,Obstetrics and Gynecology ,Identification (biology) ,Biology ,Sperm ,Gene ,Molecular biology - Published
- 2010
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11. Bacille Calmette-Guérin intravesical instillation and erectile function: is there a concern?
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Salvatore Micali, Giampaolo Bianchi, M. Giacometti, M. C. Sighinolfi, S. De Stefani, A. Mofferdin, and N. Ferrari
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medicine.medical_specialty ,Bladder cancer ,business.industry ,Urology ,Incidence (epidemiology) ,General Medicine ,Bacille Calmette Guerin ,Erectile function ,medicine.disease ,Surgery ,Endocrinology ,Erectile dysfunction ,Lower urinary tract symptoms ,Cohort ,medicine ,International Prostate Symptom Score ,business - Abstract
The aim of our study was to evaluate the effect of bacille Calmette-Guerin (BCG) therapy on erectile function in a cohort of male patients affected by non-muscle invasive bladder cancer. Thirty male patients undergoing BCG treatment for non-muscle invasive bladder cancer were enrolled in the study. Their mean age was 60.4 years. None of the patients had risk factors for erectile dysfunction (ED). All subjects underwent a BCG standard schedule therapy (once weekly instillation for 6 weeks). International Index of Erectile Function (IIEF-5) and International Prostate Symptom score (I-PSS) were addressed to the patients during the treatment schedule (at fourth or fifth instillation) and 1 month after the last instillation. The mean IIEF-5 score was 17.6 +/- 6.7 during therapy and 21.7 +/- 2.92 a month after the last instillation (P=0.008). Baseline ED and the association with lower urinary tract symptoms are variables significantly connected with post-treatment results (P=0.016 and 0.00 respectively) whereas the age seems not to be related to ED (P=0.256). No major side effects were recorded. It is concluded that BCG treatment is effective for prophylaxis of non-muscle invasive bladder cancer; however, it may induce a high incidence of ED. Although this effect is transient and reversible, erectile failure is another source of psychological distress that adversely affects the quality of life of men undergoing BCG treatment.
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- 2007
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12. Blastocoele aspiration methods and its clinical use
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Simone Palini, Mariangela Primiterra, Luca Galluzzi, and S De Stefani
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General Medicine - Published
- 2015
13. Medical Therapy of Urolithiasis
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M. Grande, Maria Chiara Sighinolfi, S. De Stefani, Salvatore Micali, C. De Carne, and Giampaolo Bianchi
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renal calculi ,Nephrology ,medicine.medical_specialty ,Colic ,Urology ,medicine.medical_treatment ,Calcium oxalate ,Allopurinol ,Lithotripsy ,Nephrolithiasis ,chemistry.chemical_compound ,Urolithiasis ,Internal medicine ,medicine ,Humans ,Hypercalciuria ,Renal colic ,Thiazide ,business.industry ,medicine.disease ,Hyperuricosuria ,Surgery ,chemistry ,Urinary Calculi ,Therapy ,medicine.symptom ,business ,Phytotherapy ,medicine.drug - Abstract
Nephrolithiasis treatment has become easier and less invasive with the development of extracorporeal shockwave lithotripsy (SWL) and endourologic techniques. However, medical therapy represents a well-established and complementary approach that can improve the efficacy of SWL and endourology. During recent decades, pharmacologic intervention has become more effective in stone disease: drugs can control the pain of renal colic, interfere at various levels in lithogenesis, and contribute to the expulsion of stones. It is well known that lithogenesis is a multifactorial process influenced by environmental-nutritional factors (low urinary volume, diet rich in animal protein, etc) and metabolic alterations; i.e., hypercalciuria, hyperuricosuria, and deficiency of stone-inhibiting factors (citrate, magnesium, glycosaminoglycans [GAGs]). Specific drugs such as citrate, allopurinol, and thiazide represent highly effective treatments for the promoting factors. Furthermore, recent findings suggest an interesting role for a phytotherapeutic agent, Phillantus niruri, and its inhibitory action on calcium oxalate crystallization related to the higher incorporation of GAGs into the calculi. Another step forward in medical management of stone disease is expulsive therapy. Many studies have proven the efficacy of medical expulsive therapy with nifedipine and alpha-blockers: their specific action on ureteral smooth muscle in association with anti-edema drugs accounts for their efficacy in expelling ureteral stones. In this paper, we provide an update on the medical treatment of stone disease, focusing our attention on what is known and what is new in renal colic and litholithic and expulsive medical therapy.
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- 2006
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14. Experimental varicocele in the rat: early evaluation of the nitric oxide levels and histological alterations in the testicular tissue
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V. Silingardi, S. De Stefani, Simone Giulini, F. Giusti, Alessandro Volpe, A. Mofferdin, Antonio Celia, Giampaolo Bianchi, Antonino Maiorana, Salvatore Micali, and Maria Chiara Sighinolfi
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Male ,Pathology ,medicine.medical_specialty ,Gonad ,Testicular tissue ,Urology ,Varicocele ,Statistical difference ,rat germinal cells ,Iliac Vein ,Biology ,Nitric Oxide ,Male infertility ,Nitric oxide ,chemistry.chemical_compound ,Endocrinology ,experimental varicocele ,Testis ,medicine ,Animals ,Rats, Wistar ,antioxidant agents ,Ligation ,Infertility, Male ,testicular nitric oxide ,General Medicine ,medicine.disease ,Sperm ,Rats ,medicine.anatomical_structure ,chemistry ,Left Spermatic Vein - Abstract
The relationship between varicocele and male infertility remains to be explained. Oxidative damage because of the testicular venous backflow may represent one of the causes of gonad injury and seems to precede the histological alteration. Therefore measuring the values of spermatic or intratesticular nitric oxide (NO) could be useful in evaluating this oxidative distress. The aim of this study is to assess the role of testicular NO in early detection of the damages induced by an experimental varicocele in the Wistar rat. A left varicocele was induced in 10 animals (group A). A control group of 10 rats was performed (group B). Animals were killed 3 months after the operation. Both testicles were harvested, weighed and sectioned in two equal parts: one for the evaluation of the NO level and the other one for histological examination. All the rats in group A showed a conspicuous dilatation of the left spermatic vein. The histopathological analysis was normal in both the groups. Biochemistry showed a meaningful statistical difference (P < 0.001) in the concentrations of NO among the specimens of the left and right gonads in group A but no difference was found in group B. The increase in NO values and the presence of other oxidant agents represent the first sign of testicular distress and it seems to anticipate histopathological changes. As it is well known that a great difference exist between human and animal sperm, NO could therefore in the future be taken into consideration together with others parameters for the evaluation of patient who is affected by varicocele.
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- 2005
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15. Penile Fracture and Associated Urethral Injury
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R. Stubinski, S. De Stefani, Alchiede Simonato, F. Ferneti, and G. Carmignani
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Adult ,Male ,endocrine system ,medicine.medical_specialty ,Fractures, Cartilage ,lcsh:Medicine ,lcsh:Technology ,General Biochemistry, Genetics and Molecular Biology ,Blunt ,Urethra ,medicine ,Original Report ,Humans ,lcsh:Science ,General Environmental Science ,Surgical repair ,Fracture Healing ,business.industry ,lcsh:T ,Penile fracture ,Urethral rupture ,lcsh:R ,General Medicine ,Plastic Surgery Procedures ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Treatment Outcome ,Blunt trauma ,lcsh:Q ,business ,Penis ,Tunica albuginea (penis) - Abstract
Fracture of the penis is an uncommon pathology. It consists in a rupture of the tunica albuginea of one or both corpora cavernosa following injury to an erect penis. The most common causes are blunt trauma during sexual intercourse, masturbation, unconscious nocturnal penile manipulation or a fall onto the erect penis. The reason why rupture of the albuginea occurs only during erection lies in the fact that in the normal flaccid condition the penis occupies a position which is well protected against blows or blunt traumas. In the erect penis the tunica albuginea thins from 2 mm to 0.5 0.25 mm and thus it is more susceptible to traumatic tearing. Penile fracture associated with urethral injury is even more uncommon and accounts for 10 to 20% of reported cases. Prompt diagnosis and immediate surgical repair allows for earlier resumption of sexual activity and gives a lower incidence of penile chordee secondary to blood clot absorption and fibrous tissue formation. Surgery is mandatory for the prevention of late sequelae following injury especially in cases associated with urethral rupture. At times the corporeal tear is very large and in patients with concomitant lesions involving the urethra surgical repair can become difficult and require particular technical shrewdness. We report the surgical repair of 8 cases of penile fracture, two of which were complex involving both corpora cavernosa and an associated partial rupture of the urethra.
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- 2004
16. Dornier Lithotripter S
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C. Di Pietro, Antonio Celia, Giampaolo Bianchi, S. De Stefani, Salvatore Micali, and C. De Carne
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medicine.medical_specialty ,business.industry ,Urology ,Radiography ,Treatment outcome ,Follow up studies ,Stone size ,urologic and male genital diseases ,female genital diseases and pregnancy complications ,Surgery ,Extracorporeal shockwave lithotripsy ,medicine ,Safety Equipment ,business ,Cohort study - Abstract
Introduction: We assessed the short-term efficacy of extracorporeal shockwave lithotripsy with the Dornier Lithotripter S in the treatment of renal and ureteral stones. Materials and Methods: Between February and April 2003, 32 renal and 19 ureteral stones were treated. Patients were evaluated 1 and 3 months afterwards. Stone size and location, total number of shockwaves and the stone-free rate were taken into consideration. Results: The stone-free rate for ureteral stones was 63% at 1 month and 84.2% at 3 months. The stone-free rate for renal calculi was 75% at 1 month and 87.5% at 3 months. The overall stone-free rate was 70.6% at 1 month and 86.3% at 3 months. Analgesia was necessary in 12 patients (23.5%). No serious complications were seen, except for one steinstrasse. Conclusions: The Dornier Lithotripter S is very effective in the treatment of renal and ureteral calculi.
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- 2004
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17. Indwelling Ureteral Stents and Sexual Health: A Prospective, Multivariate Analysis
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M C, Sighinolfi, S, Micali, S, De Stefani, A, Mofferdin, M, Grande, A, Grande, M, Giacometti, N, Ferrari, M, Rivalta, and G, Bianchi
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Male ,medicine.medical_specialty ,Urology ,medicine.medical_treatment ,Ureter ,Erectile Dysfunction ,Quality of life ,Lower urinary tract symptoms ,Surveys and Questionnaires ,medicine ,Humans ,Prospective Studies ,Prospective cohort study ,business.industry ,ureter ,stents ,female ,male ,sexuality ,Stent ,equipment and supplies ,medicine.disease ,Menopause ,surgical procedures, operative ,Erectile dysfunction ,medicine.anatomical_structure ,Multivariate Analysis ,Quality of Life ,Female ,Stents ,International Prostate Symptom Score ,business ,Sexuality ,Ureteral Obstruction - Abstract
Ureteral stents are common devices in urological practice. However, a stent may provoke lower urinary tract symptoms that severely affect quality of life. We evaluated the relationship between ureteral stents and male erection/female sexuality.A total of 30 men and 20 women undergoing ureteral stent positioning were considered. Patients affected by risk factors for erectile dysfunction or hormonal and metabolic alterations were excluded. Hystero-ovariectomy and menopause were considered exclusion criteria. Three questionnaires were administered before stenting and 45 to 60 days after stent positioning, including the International Prostate Symptom Score, the International Index of Erectile Function-5 for men and the Female Sexual Function Index for women.Mean age was 45 years in men and 39 years in women. The mean+/-SD International Index of Erectile Function-5 score was 23.2+/-1.27 and the mean Female Sexual Function Index score was 32.15+/-2.71 before stent positioning. No lower urinary tract symptoms were reported before the procedure. After the ureteral stent was indwelling the mean International Index of Erectile Function-5 score was 13.5+/-4.01 and the mean Female Sexual Function Index score was 23.6+/-14.66 (p=0.000 and 0.007, respectively). Of 30 men 25 reported a pathological International Index of Erectile Function-5 score and 6 of 20 women denied any sexual activity due to stent related anxiety, resulting in the minimum Female Sexual Function Index score. In the remaining 14 women sexual life was not significantly impaired by the ureteral stent (p=0.08).Ureteral stents impaired the quality of sexual life in male and female subjects. In men the most important distress was in regard to erectile function, probably related to lower urinary tract symptoms. Conversely female sexuality appeared to be severely impaired due to stent related psychological concerns.
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- 2007
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18. Immediate Improvement in Penile Hemodynamics after Cessation of Smoking: Previous Results
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Salvatore Micali, A. Mofferdin, S. De Stefani, Giampaolo Bianchi, Arrigo F G Cicero, Maria Chiara Sighinolfi, Sighinolfi M.C., Mofferdin A., De Stefani S., Micali S., Cicero A., and Bianchi G.
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Adult ,Male ,Nephrology ,medicine.medical_specialty ,Time Factors ,genetic structures ,Urology ,medicine.medical_treatment ,peak systolic velocity ,Hemodynamics ,Smoking cessation ,smoking ,Cigarette smoking ,Internal medicine ,medicine ,Humans ,Erectile dysfunction ,Prospective Studies ,Prospective cohort study ,business.industry ,penile hemodynamics ,Ultrasonography, Doppler ,Recovery of Function ,Color doppler ,Middle Aged ,medicine.disease ,Surgery ,Increased risk ,Cardiology ,business ,Blood Flow Velocity ,Penis ,circulatory and respiratory physiology - Abstract
OBJECTIVES: To assess the chronologic relationship between the cessation of smoking and the restoration of erectile function. Smoking is associated with an increased risk of erectile dysfunction. METHODS: Twenty active smokers (20 to 40 cigarettes/day) affected by erectile dysfunction (International Index of Erectile Function 5-item score less than 21) were enrolled in the study. The mean age was 40 years. All the patients underwent penile color Doppler ultrasonography during the basic and dynamic phases (10 microg prostaglandin E1). A second Doppler evaluation was performed 24 to 36 hours after cessation of smoking. The peak systolic velocity (PSV) and end-diastolic velocity (EDV) were recorded. The PSV and EDV cutoff value was 30 cm/s and 5 cm/s, respectively. RESULTS: Of the 20 patients, 10 (50%) had normal PSV values but only 5 (25%) had normal EDV values at the baseline Doppler evaluation. All the patients (100%) had normal PSV values at the second penile Doppler evaluation after smoking withdrawal, and 17 (85%) also had normal EDV values. The average PSV was 40.1 and 50.3 cm/s (P = 0.09) and the mean EDV was 6.8 and 2.4 cm/s (P
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- 2007
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19. A Knotted Multilenght Ureteral Stent: A Rare Complication
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A. Celia, G. Bianchi, A. Mofferdin, C. A. Pollastri, C. Di Pietro, B. Baisi, S. De Stefani, and M. C. Sighinolfi
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medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,food and beverages ,Stent ,General Medicine ,Ureteral stents ,equipment and supplies ,urologic and male genital diseases ,female genital diseases and pregnancy complications ,Surgery ,surgical procedures, operative ,medicine ,business ,Complication ,Upper urinary tract - Abstract
Indwelling Ureteral stents are fundamental instruments for modern urologist. They are commonly used in the management of upper urinary tract obstruction. Complications are rare. Knotting of the stent at its proximal coiled end is a very rare event but it can be resolved easily by an endoscopic approach if promptly recognized.
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- 2004
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20. Microlaparoscopy in Sex Reassignment Surgery
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Marco Raber, Emanuele Belgrano, G. Savaco, U. Moro, Carlo Trombetta, S. De Stefani, S. D., Stefani, Trombetta, Carlo, M., Raber, G., Savaca, U., Moro, and Belgrano, Emanuele
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Adult ,Male ,Microsurgery ,medicine.medical_specialty ,Adult, Genitalia ,surgery, Humans, Laparoscopy ,methods, Male, Microsurgery ,methods, Orchiectomy ,methods, Reconstructive Surgical Procedures ,methods, Transsexualism ,surgery, Treatment Outcome, Urogenital Surgical Procedures ,methods ,lcsh:Medicine ,Case Report ,Genitalia, Male ,lcsh:Technology ,General Biochemistry, Genetics and Molecular Biology ,surgery ,Blunt dissection ,Prostate ,methods, Reconstructive Surgical Procedure ,Humans ,Medicine ,Genitalia ,Reconstructive Surgical Procedures ,lcsh:Science ,General Environmental Science ,lcsh:T ,business.industry ,lcsh:R ,Direct observation ,Sex reassignment surgery (female-to-male) ,General Medicine ,Plastic Surgery Procedures ,Urogenital Surgical Procedures ,Surgery ,Perineum ,Dissection ,Treatment Outcome ,medicine.anatomical_structure ,Rectal wall ,surgery, Treatment Outcome, Urogenital Surgical Procedure ,Laparoscopy ,lcsh:Q ,business ,Male to female ,Orchiectomy ,Transsexualism - Abstract
Sex reassignment (male to female surgery) is a standard operation which is aimed at constructing female genitalia and obtaining a cosmetic and functional result that is similar to that of a normal female subject. The ideal surgical procedure has not yet been described, but the various techniques which have been proposed in the literature are similar. The most cumbersome maneuver of the procedure is that of creating a neovaginal cavity inside the perineum. This step is generally carried out by means of blunt dissection between the rectal wall and the prostate, but most of the surgery is blindly performed without visual control. In these conditions, the risk of rectal injury is high, and may lead to severe intraoperative complications. Microlaparoscopy allows for a direct observation of the perineal dissection from inside the peritoneal cavity, thus avoiding risk of rectal injury. The technique is simple to perform, is non-invasive, and only 15 minutes are added to the operation.
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- 2004
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21. Elective segmental ureterectomy for transitional cell carcinoma of the ureter: long-term follow-up in a series of 73 patients
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Alchiede, Simonato, V, Varca, A, Gregori, A, Benelli, M, Ennas, A, Lissiani, M, Gacci, S, De Stefani, M, Rosso, S, Benvenuto, G, Siena, E, Belgrano, F, Gaboardi, M, Carini, G, Bianchi, and G, Carmignani
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Aged, 80 and over ,Male ,Carcinoma, Transitional Cell ,Time Factors ,Ureteral Neoplasms ,Biopsy ,Middle Aged ,Survival Rate ,Treatment Outcome ,Italy ,Elective Surgical Procedures ,Ureteroscopy ,Humans ,Urologic Surgical Procedures ,Female ,Prospective Studies ,Ureter ,Aged ,Follow-Up Studies - Abstract
What's known on the subject? and What does the study add? Upper Urinary Tract (UUT) Transitional Cell Carcinoma (TCC) is an uncommon disease and represents approximately 5% of all urothelial carcinomas. We report our series on 73 patients treated with Kidney Sparing Surgery for UUT TCC. Good results have been achieved in terms of oncological outcome comparing this conservative approach to the radical nephrourectomy.• To report the long-term oncological outcome in patients with transitional cell carcinoma of the ureter electively treated with kidney-sparing surgery. • To compare our data with the few series reported in the literature.• We considered 73 patients with transitional cell carcinoma of the distal ureter treated in five Italian Departments of Urology. • The following surgeries were carried out: 38 reimplantations on psoas hitch bladder (52%), 21 end-to-end anastomoses (28.8%), 11 direct ureterocystoneostomies (15.1%) and three reimplantations on Boari flap bladder (4.1%). • The median follow-up was 87 months.• Tumours were pTa in 42.5% of patients, pT1 in 31.5%, pT2 in 17.8% and pT3 in 8.2%. • Recurrence of bladder urothelial carcinoma was found in 10 patients (13.7%) after a median time of 28 months. • The bladder recurrence-free survival at 5 years was 82.2%. • The overall survival at 5 years was 85.3% and the cancer-specific survival rate at 5 years was 94.1%.• Our data show that segmental ureterectomy procedures do not result in worse cancer control compared with data in the literature regarding nephroureterectomy.
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- 2012
22. The role of microsurgery and means of magnification
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S. De Stefani
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business.industry ,medicine.medical_treatment ,medicine ,Magnification ,General Medicine ,Microsurgery ,business ,Biomedical engineering - Abstract
An objective of hypospadias repair is to provide a penis that is normal in function and appearance. The adoption of microsurgical techniques enables this objective to be reached in a great percentage of cases also in younger patients. Nevertheless in this case, microsurgery should be considered as a philosophical behaviour rather than a surgical technique conventionally based on the utilization of the microscope, jeweller's forceps and microscissors. What is important is the concept of microsurgery; i.e. the adoption of atraumatic techniques and great respect for the tissues. Strict and constant application of these rules greatly improves final results and increases the percentage of success of reconstructive surgery of the urethra.
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- 1994
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23. Testicular metastasis of signet ring cell tumour of unknown origin: Diagnostic features of a tricky case
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G, Saredi, M, Rivalta, M C, Sighinolfi, G, Rossi, F, Fidanza, C, Guarasci, A M, Cesinaro, N, De Maria, S, De Stefani, and G, Bianchi
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Male ,Fatal Outcome ,Humans ,Prostatic Neoplasms ,Adenocarcinoma ,Carcinoma, Signet Ring Cell ,Aged ,Signet ring cell adenocarcinoma ,Signet ring cell tumour ,Testicular metastasis ,Urology ,Endocrinology - Abstract
We introduce the diagnostic complexity of a testicular metastasis by signet ring cell adenocarcinoma of unknown origin. Testicular metastases are a rare event but, particular after 50 years of age, a testicular mass could represent a metastasis.
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- 2011
24. Saphenous vein harvesting by ‘stripping’ technique and ‘W’-shaped patch covering after plaque incision in treatment of Peyronie's disease
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G Savoca, Emanuele Belgrano, F. Scieri, Ignazio Gattuccio, S. Ciampalini, and S. De Stefani
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Male ,medicine.medical_specialty ,business.industry ,Urology ,Penile Induration ,medicine.disease ,Transplantation, Autologous ,Stripping (fiber) ,Surgery ,Vein harvesting ,Treatment Outcome ,Peyronie disease ,Penile Diseases ,Tissue and Organ Harvesting ,medicine ,Humans ,Saphenous Vein ,Peyronie's disease ,business ,Vascular Surgical Procedures - Abstract
Harvesting of the saphenous vein tract by means of leg stripping is proposed in the treatment of Peyronie's disease. The technique of W-shaped saphenous vein after plaque incision to correct severe penile deformity associated with Peyronie's disease is described. Graft material was obtained from the lower saphenous vein by means of distal 'leg short stripping' technique. The size and number of tunical incisions depended on the size of the plaque. A 15 cm venous segment is generally sufficient to cover the defect. The venous segment used was W-shaped, assembled with 6/0 polydioxanone (PDS) uninterrupted sutures and then sutured to the albuginea defect. In our preliminary series of eight patients, penile shortening and erectile dysfunction is absent. Complete correction of penile deformity was achieved in seven patients (87.5%). One patient had minimal residual curvature (20 degrees ) which did not result in difficulty with intromission. Saphenous harvesting by the stripping technique is not an invasive procedure and is quick and simple to perform. The W-shaped assembling technique is safe because the piece of saphena is kept intact and may be suited properly to the albuginea defect.
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- 2000
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25. Un anno di letteratura urologica sulla calcolosi urinaria
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Salvatore Micali, N. Ferrari, M. Rivalta, Giampaolo Bianchi, Giovannalberto Pini, S. De Stefani, and M. C. Sighinolfi
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lcsh:Internal medicine ,calcolosi urinaria ,business.industry ,Medicine ,Pharmacology (medical) ,General Medicine ,business ,lcsh:RC31-1245 ,lcsh:Diseases of the genitourinary system. Urology ,lcsh:RC870-923 - Abstract
non disponibile
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- 2009
26. Aerosol characterization at the Stelvio National Park
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E. Della Bella, A. Fumagalli, M.G. Braga Marcazzan, R. Ricci, M. Fioletti, and S. De Stefani
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Fluid Flow and Transfer Processes ,Pollution ,Atmospheric Science ,Provenance ,Environmental Engineering ,Meteorology ,National park ,Mechanical Engineering ,media_common.quotation_subject ,Particulates ,Atmospheric sciences ,Aerosol ,Environmental science ,Statistical analysis ,Air mass ,media_common - Abstract
Statistical analysis of particulate matter and element concentration time series has evidenced dust long range transport, regional background and sources of pollution at an alpine station. A correlation between air mass provenance and rain acidity or alcalinity has been found.
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- 1991
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27. Extracorporeal shock wave lithotripsy in an elderly population: how to prevent complications and make the treatment safe and effective
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Giampaolo Bianchi, Salvatore Micali, A. Mofferdin, M. Grande, Maria Chiara Sighinolfi, and S. De Stefani
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Aged, 80 and over ,education.field_of_study ,medicine.medical_specialty ,business.industry ,Urology ,medicine.medical_treatment ,Population ,Shock wave lithotripsy ,Lithotripsy ,Extracorporeal shock wave lithotripsy ,Treatment Outcome ,Elderly population ,Concomitant ,Cohort ,Medicine ,Humans ,Safety ,business ,Complication ,education ,Intensive care medicine ,complications treatment [Extracorporeal shock wave lithotripsy elderly population] ,Aged - Abstract
The aim of our study is to consider the feasibility and the results of shock wave lithotripsy (SWL) in an elderly cohort of patients, considering different diseases and concomitant morbidity.From January 2003 up to July 2006, a total of 1100 SWL treatments were performed in our Stone Centre with Dornier Lithotripter S device. We retrospectively analyzed all the treatments carried out in patients older than 70 years of age, collecting a total of 130 patients. The average age was 75.1 years (range: 70-89). Stone location was renal in 95 and ureteral in 45 patients. Information about SWL outcomes and complications were collected as well as patient's characteristics and treatment modalities.Average stone size was 10.2+/-3.4 and 8.7+/-3.1 for the renal and ureteral location, respectively. 73 out of 140 patients (52.1%) were stone free after a single treatment; 49 patients (35%) required an adjunctive session, whereas SWL was unsuccessful in 18 (12.8%) patients. We observed 64, 24, 21, 10, 31 cases of concomitant arterial hypertension, diabetes mellitus, chronic renal failure, solitary kidney condition and previous neoplastic pathologies. A total of 8 and 6 subjects had previous cardiac surgery and atrial fibrillation respectively, thus requiring a warfarin scheduled conversion to low molecular weight heparin. Five patients had a pace maker implant and three patients an abdominal aortic aneurism. No SWL-related complications were found in this series considering both urological and systemic features.SWL represents the treatment of choice for urolithiasis, and it has to be recommended especially to geriatric patients. In those subjects, SWL complications can be avoided with a proper and personalized preparation, together with an ECG and ultrasound continuously monitored procedure.
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- 2008
28. Urological concerns: Should trans-urethral catheter be located over or under the thigh?
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M. Rivalta, A. Mofferdin, Giampaolo Bianchi, M. Grande, Salvatore Micali, C. De Carne, Maria Chiara Sighinolfi, and S. De Stefani
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Bladder catheter ,Pressure ,Compliance ,medicine.medical_specialty ,Urinary bladder ,business.industry ,Obstetrics and Gynecology ,Bladder catheterization ,Thigh ,Surgical procedures ,General Biochemistry, Genetics and Molecular Biology ,Surgery ,Catheter ,medicine.anatomical_structure ,medicine ,Humans ,business ,Urinary Catheterization ,Urethral catheter - Abstract
Introduction Bladder catheterization is a common practice after several surgical procedures; a wrong trans-urethral catheter position can affect the outcomes of some urological maneuvers. We assess with a physical model the variation of intra-vesical pressures due to different locations of the catheter. Materials and methods Using a plastic bag fulfilled with 5 l of normal saline, we try to reproduce bladder condition assessing pressures in case of catheter located over or under the thigh. Results In case of catheter over the thigh, the flow of liquid is not allowed, and only a pressure of 23 cm of water induces the passage of fluid. Conclusion A wrong catheter position may adversely affect intravesical pressures; this finding has to be taken into consideration, especially when dealing with post-urological surgery catheterization.
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- 2008
29. Knotted urethral catheter in an 80-year-old woman: prevention and management of this unusual complication
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A. Beato, Salvatore Micali, A. Mofferdin, S. De Stefani, Maria Chiara Sighinolfi, N. Ferrari, and Giampaolo Bianchi
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Aged, 80 and over ,medicine.medical_specialty ,business.industry ,food and beverages ,Obstetrics and Gynecology ,urethral catheter ,General Biochemistry, Genetics and Molecular Biology ,Surgery ,Catheter ,Equipment failure ,surgical procedures, operative ,Urethra ,medicine.anatomical_structure ,prevention ,stomatognathic system ,Medicine ,Humans ,Equipment Failure ,Female ,business ,Complication ,Urinary Catheterization ,Urethral catheter - Abstract
Intravesical catheter knotting represents a rare event, especially described in paediatric literature. We report a case of a catheter knot, occurring in an 80-year-old woman, managed by means of sustained traction.
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- 2008
30. Well-differentiated giant scrotal liposarcoma: case presentation and management
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Giampaolo Bianchi, L. Reggiani Bonetti, A. Dotti, F. Fidanza, G. Saredi, Salvatore Micali, S. De Stefani, Maria Chiara Sighinolfi, and C. De Gaetani
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Male ,scrotal ,liposarcoma ,endocrine system ,medicine.medical_specialty ,Urology ,Case presentation ,Liposarcoma ,urologic and male genital diseases ,Scrotal Neoplasm ,Endocrinology ,Scrotum ,medicine ,Humans ,neoplasms ,Aged ,urogenital system ,business.industry ,Soft tissue sarcoma ,Cell Differentiation ,General Medicine ,medicine.disease ,Well differentiated ,Surgery ,body regions ,medicine.anatomical_structure ,Genital Neoplasms, Male ,business ,Surgical ablation - Abstract
Scrotal liposarcoma is an uncommon disease, usually found after the fifth decade. We describe the case of a well-differentiated scrotal liposarcoma associated with a considerable inflammatory reaction, treated with surgical ablation.
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- 2008
31. Efficacy of expulsive therapy using nifedipine or tamsulosin, both associated with ketoprofene, after shock wave lithotripsy of ureteral stones
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M. Grande, Salvatore Micali, Giampaolo Bianchi, S. De Stefani, and Maria Chiara Sighinolfi
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Nephrology ,Adult ,Male ,Tamsulosin ,medicine.medical_specialty ,Nifedipine ,Urology ,medicine.medical_treatment ,expulsive therapy ,Lithotripsy ,lithotripsy ,Ureter ,nifedipine ,tamsulosin ,ketoprofene ,ureteral stones ,Internal medicine ,medicine ,Humans ,Prospective Studies ,Prospective cohort study ,Adrenergic alpha-Antagonists ,Aged ,Sulfonamides ,business.industry ,Ultrasound ,Anti-Inflammatory Agents, Non-Steroidal ,Middle Aged ,Extracorporeal shock wave lithotripsy ,Combined Modality Therapy ,Surgery ,medicine.anatomical_structure ,Treatment Outcome ,Ketoprofen ,Female ,Urinary Calculi ,business ,medicine.drug - Abstract
Extracorporeal shock wave lithotripsy (ESWL) is currently considered one of the main treatments for ureteral stones. Some studies have reported the effectiveness of pharmacologic therapies (calcium antagonists or alpha-blockers) in facilitating ureteral stone expulsion after ESWL. We prospectively evaluated the efficacy, after ESWL, of nifedipine on upper-middle ureteral stones, and tamsulosin on lower ureteral stones, both associated to ketoprofene as anti-edema agent. From January 2003 to March 2005 we prospectively evaluated 113 patients affected by radiopaque or radiolucent ureteral stones. Average stone size was 10.16 +/- 2.00 mm (range 6-14 mm). Thirty-seven stones were located in the upper ureter, 27 in the middle ureter, and 49 in the lower ureter. All patients received a single session of ESWL (mean number of shock waves: 3,500) by means of a Dornier Lithotripter S (mean energy power for each treatment: 84%). Both ultrasound and X-ray were used for stone scanning. After treatment, 63 of 113 patients were submitted to medical therapy to aid stone expulsion: nifedipine 30 mg/day for 14 days administered to 35 patients with upper-middle ureteral stones (group A1) and tamsulosin 0.4 mg/day for 14 days administered to 28 patients with stones located in the distal ureter (group A2). The remaining 50 patients were used as a control group (29 upper-middle ureteral stones-B1-and 21 lower ureteral stones-B2-), receiving only pain-relieving therapy. No significant difference in stone size between the groups defined was observed. Stone clearance was assessed 1 and 2 months after ESWL by means of KUB, ultrasound scan and/or excretory urography. A stone-free condition was defined as complete stone clearance or the presence of residual fragments smaller than 3 mm in diameter. The stone-free rates in the expulsive medical therapy group were 85.7 and 82.1% for the nifedipine (A1) and tamsulosin (A2) groups respectively; stone-free rates in the control groups were 51.7 and 57.1% (B1 and B2, respectively). Five patients (14.3%) in group A1, 5 (17.8%) in group A2, 14 (48.3%) in group B1 and 9 (42.8%) in group B2 were not stone-free after a single ESWL session and required ESWL re-treatment or an endoscopic treatment. Medical therapy following ESWL to facilitate ureteral stone expulsion results in increased 1- and 2-month stone-free rates and in a lower percentage of those needing re-treatment. The efficacy of nifedipine for the upper-mid ureteral tract associated with ketoprofene makes expulsive medical therapy suitable for improving overall outcomes of ESWL treatment for ureteral stones.
- Published
- 2007
32. Changes in peak systolic velocity induced by chronic therapy with phosphodiesterase type 5 inhibitor
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S. De Stefani, Salvatore Micali, Giampaolo Bianchi, Maria Chiara Sighinolfi, Antonio Celia, A. Mofferdin, Arrigo F G Cicero, Sighinolfi M.C., Mofferdin A., De Stefani S., Celia A., Micali S., Cicero A., and Bianchi G.
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Adult ,Male ,medicine.medical_specialty ,Sildenafil ,Phosphodiesterase Inhibitors ,Urology ,peak systolic velocity ,Hemodynamics ,phosphodiesterase type 5 inhibitor ,Piperazines ,Sildenafil Citrate ,chemistry.chemical_compound ,Endocrinology ,Vasoactive ,Internal medicine ,chronic therapy ,medicine ,Humans ,International Index of Erectile Function ,Sulfones ,Ultrasonography, Doppler, Color ,Aged ,business.industry ,Penile Erection ,Ultrasound ,Phosphodiesterase ,type-5 inhibitor ,General Medicine ,Middle Aged ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Erectile dysfunction ,chemistry ,Purines ,cGMP-specific phosphodiesterase type 5 ,Cardiology ,phosphodiesterase ,business ,Penis ,Blood Flow Velocity - Abstract
Summary The aim of this study was to assess the influence of chronic therapy with phosphodiesterase type-5 inhibitor on penile haemodynamics at colour Doppler ultrasound. Thirty patients affected by erectile dysfunction (ED) of different aetiology tested with the International Index of Erectile Function (IIEF-5) were evaluated with penile colour Doppler ultrasound during basic and dynamic phases (10 μg PGE1) before and after chronic self-administration of sildenafil citrate (dosage: 100 mg as required, two to three times a week) for a period of 5–20 months (mean: 12.3). Treatment was interrupted 14–21 days before the second ultrasound evaluation. Peak systolic velocity (PSV) and end-diastolic velocity (EDV) were recorded by means of colour Doppler; cut off values were 25 and 5 cm s−1 respectively. Data were compared by nonparametric tests. Twenty-two of the 30 patients showed normal pre-treatment PSV, while eight of 30 had an insufficient arterial flow. Mean pre-treatment EDV was 4.7 ± 0.5. After chronic therapy with sildenafil, a global improvement of 10.5% on PSV was seen (P
- Published
- 2006
33. Can Phyllantus niruri (Uriston ®) affect the efficacy of extracorporeal shock wave lithiotrispy or renal stones. A randomised, prospective, long-term study
- Author
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Salvatore Micali, M. Grande, Maria Chiara Sighinolfi, Giampaolo Bianchi, Arrigo F G Cicero, Antonio Celia, S. De Stefani, Micali S., Sighinolfi M.C., De Stefani S., Grande M., Cicero A., and Bianchi G.
- Subjects
Nephrology ,Adult ,Male ,medicine.medical_specialty ,Phyllanthus ,Randomization ,Time Factors ,Urology ,medicine.medical_treatment ,niruri ,extracorporeal ,lithotripsy ,renal stones ,Lithotripsy ,law.invention ,Kidney Calculi ,Randomized controlled trial ,law ,Internal medicine ,medicine ,Humans ,Prospective Studies ,Kidney stone ,Prospective cohort study ,Aged ,biology ,business.industry ,Plant Extracts ,Middle Aged ,biology.organism_classification ,medicine.disease ,Extracorporeal shock wave lithotripsy ,Surgery ,Female ,business ,Kidney disease ,Phytotherapy ,Phyllantus niruri - Abstract
PURPOSE: Phyllanthus niruri is a plant used in Brazilian folk medicine for the treatment of urolithiasis. We assessed the efficacy of P. niruri after extracorporeal shock wave lithotripsy for renal stones. MATERIALS AND METHODS: We prospectively evaluated 150 patients with renal stones that were as large as 25 mm and composed of calcium oxalate. All patients received 1 to 3 extracorporeal shock wave lithotripsy sessions by Dornier Lithotriptor S. After treatment 78 of 150 patients (52%) underwent therapy with Uriston, a P. niruri extract (2 gm daily) for at least 3 months (group 1). Otherwise 72 of 150 patients (48%) were used as a control group (group 2). No significant difference in stone size between the 2 groups was found. Stone clearance was assessed after 30, 60, 90 and 180 days by abdominal x-ray and ultrasound scan. RESULTS: Stone-free rate (stone-free defined as the absence of any stone or residual fragments less than 3 mm) was 93.5% in group 1 and 83.3% in group 2 (p = 0.48) at the end point of the followup (180 days). For lower caliceal stones (56 patients) the stone-free rate was 93.7% in the treatment group and 70.8% in the control group (p = 0.01). Re-treatment need for group 1 was 39.7% and for group 2 it was 43.3% (p = 0.2). No side effects were recorded with extracorporeal shock wave lithotripsy or P. niruri therapy. CONCLUSIONS: Regular self-administration of P. niruri after extracorporeal shock wave lithotripsy for renal stones results in an increased stone-free rate that appears statistically significant for lower caliceal location. Its efficacy and the absolute lack of side effects make this therapy suitable to improve overall outcomes after extracorporeal shock wave lithotripsy for lower pole stones.
- Published
- 2006
34. Experience with fibrin glue in bulbar urethral reconstruction using dorsal buccal mucosa graft
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Salvatore Micali, Giampaolo Bianchi, Maria Chiara Sighinolfi, S. De Stefani, Guido Barbagli, Filippo Annino, and C. A. Pollastri
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Adult ,Male ,Dorsum ,medicine.medical_specialty ,Urologic Surgical Procedures, Male ,Urology ,Urethroplasty ,medicine.medical_treatment ,Fibrin Tissue Adhesive ,Oral cavity ,Buccal mucosa ,Fibrin ,Urethra ,stomatognathic system ,Experience with fibrin glue in bulbar urethral reconstruction using dorsal buccal mucosa graft ,medicine ,Humans ,Fibrin glue ,Urethral Stricture ,biology ,business.industry ,Mouth Mucosa ,Anatomy ,Surgery ,surgical procedures, operative ,medicine.anatomical_structure ,biology.protein ,business ,Bulbar urethral stricture - Abstract
Buccal mucosa dorsal onlay graft urethroplasty represents a widespread method for bulbar urethral stricture repair. We describe a modified procedure with the use of fibrin glue applied on the receiving bed before graft location.
- Published
- 2006
35. Valutazione ecografica e TC di pielonefrite acuta in paziente affetta da rene policistico
- Author
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S. De Stefani, C. Lodolo, Andrea Lissiani, U. Moro, Fabio Pozzi Mucelli, and Emanuele Belgrano
- Subjects
business.industry ,Medicine ,General Medicine ,business - Abstract
Autosomal dominant polycystic kidney disease is a rare nephropathy consisting of multiple cysts that alter almost all the parenchyma of the organ, leading to renal failure. A clinical case with atypical presentation is described.
- Published
- 1997
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36. Laparoscopic adrenal surgery: New frontiers
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Antonio Celia, G. Peluso, S. De Stefani, Giampaolo Bianchi, M. Grande, Maria Chiara Sighinolfi, and Salvatore Micali
- Subjects
Male ,Nephrology ,Laparoscopic surgery ,medicine.medical_specialty ,Radiofrequency ablation ,Urology ,medicine.medical_treatment ,Laparoscopic ,adrenal surgery ,Adrenal Gland Diseases ,Adrenal Gland Neoplasms ,Pheochromocytoma ,Malignancy ,Cryosurgery ,Sensitivity and Specificity ,law.invention ,Postoperative Complications ,Risk Factors ,law ,Internal medicine ,Hyperaldosteronism ,medicine ,Humans ,Minimally Invasive Surgical Procedures ,Laparoscopy ,Cushing Syndrome ,medicine.diagnostic_test ,Adrenal gland ,business.industry ,General surgery ,Gold standard ,Adrenalectomy ,medicine.disease ,Adrenal Cortex Neoplasms ,Surgery ,Treatment Outcome ,medicine.anatomical_structure ,Catheter Ablation ,Female ,business ,Follow-Up Studies - Abstract
After about 10 years of experience, laparoscopic adrenalectomy has become the gold standard for the treatment of adrenal lesions. Here, we describe the presenting features, imaging methods, and current surgical approaches to diseases of the adrenal gland. There is general agreement on the suitability of the laparoscopic approach for benign adrenal lesions, but controversy exists about using laparoscopy for suspected adrenal malignancy, metastasis, and partial adrenalectomy. This article reviews the literature on laparoscopic adrenalectomy. In particular, we focus our attention on the new surgical approaches to the gland. We evaluate the indications, operative techniques, and tools for partial adrenalectomy, and we discuss new surgical strategies such as cryosurgery and radiofrequency ablation.
- Published
- 2005
37. A knotted multi-length ureteral stent: a rare complication
- Author
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B. Baisi, A. Mofferdin, Antonio Celia, S. De Stefani, Maria Chiara Sighinolfi, Salvatore Micali, and Giampaolo Bianchi
- Subjects
Male ,Nephrology ,medicine.medical_specialty ,Urology ,medicine.medical_treatment ,Hydronephrosis ,urologic and male genital diseases ,Kidney Calculi ,Lithotripsy ,Internal medicine ,medicine ,Humans ,ureteral stent ,rare complication ,Upper urinary tract ,business.industry ,Stent ,Middle Aged ,Surgery ,surgical procedures, operative ,Equipment Failure ,Stents ,Ureteral Catheters ,Ureter ,Complication ,business - Abstract
Ureteral catheters represent essential devices in the management of upper urinary tract obstruction; complications are unusual. Knotting of the stent at its proximal coiled end is a very rare but potentially dangerous event that should be promptly recognized.
- Published
- 2005
38. Laparoscopic telementored adrenalectomy: The Italian experience
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Antonio Celia, S. De Stefani, M. Bruschi, Francesco Porpiglia, Giampaolo Bianchi, Roberto Mario Scarpa, M. Grande, and Salvatore Micali
- Subjects
Adult ,Male ,Laparoscopic ,adrenalectomy ,medicine.medical_specialty ,Adolescent ,medicine.medical_treatment ,Blood loss ,medicine ,Humans ,Laparoscopy ,Aged ,medicine.diagnostic_test ,business.industry ,Adrenalectomy ,General surgery ,Gold standard ,Middle Aged ,Telemedicine ,Endoscopy ,Surgery ,Italy ,Female ,Surgical education ,business ,Abdominal surgery - Abstract
Laparoscopy is widely accepted as the gold standard for adrenalectomy. Telementoring has been developed to reduce the complications associated with surgeon inexperience. We report our preliminary experience with laparoscopic telementored adrenalectomy. From July 2002 to May 2003, eight laparoscopic telementored adrenalectomies were performed between two separate operating sites 430 km apart. Six of these procedures were monolateral laparoscopic adrenalectomies, and one was bilateral. All cases were performed by an expert open surgeon who was skilled in laparoscopic procedure but who had no experience in laparascopic adrenalectomy All the procedures were successfully performed in a telementored fashion. The mean operative times, blood loss, and postoperative morbidity results were comparable to those for standard laparoscopic adrenalectomies reported in the literature. This preliminary experience has demonstrated the feasibility of national telementoring. It is a viable method that can potentially add to surgical education and decrease the likelihood of complications due to inexperience with new techniques.
- Published
- 2005
39. AMS 800® artificial sphincter: An unusual case of circumscribed peritonitis due to prosthethic reservoir infection
- Author
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S. Ciampalini, Emanuele Belgrano, S. De Stefani, and Dott. G. Liguori
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medicine.medical_specialty ,Unusual case ,business.industry ,medicine ,Peritonitis ,General Medicine ,medicine.disease ,business ,Artificial sphincter ,Surgery - Abstract
— We report the case of a patient who presented with circumscribed peritonitis due to infection of the intraperitoneal reservoir of an artificial sphincter. Although only parietal symptoms were evident, the balloon could not be removed without segmental ileal resection. This case suggests re-examining indications for intraperitoneal implantation of the reservoir.
- Published
- 1996
- Full Text
- View/download PDF
40. Transrectal contrast-enhanced (Levovist) ultrasonography in evaluation of urinary leakage after radical prostatectomy: a preliminary report
- Author
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G. Peluso, A. Mofferdin, Salvatore Micali, Giampaolo Bianchi, M. Paterlini, Antonio Celia, S. De Stefani, and Maria Chiara Sighinolfi
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Nephrology ,Male ,medicine.medical_specialty ,Urology ,medicine.medical_treatment ,Urinary Bladder ,Contrast Media ,Urine ,Transrectal contrast-enhanced (Levovist) ultrasonography urinary leakage radical prostatectomy ,Urinary Leakage ,Postoperative Complications ,Urethra ,Preliminary report ,Polysaccharides ,Internal medicine ,Medicine ,Humans ,Catheter removal ,Aged ,Ultrasonography ,Prostatectomy ,medicine.diagnostic_test ,business.industry ,Anastomosis, Surgical ,Middle Aged ,Contrast medium ,Transrectal ultrasonography ,business - Abstract
Quick postoperative catheter removal remains one of the main goals of radical prostatectomy, but it leads to a greater risk of urinary leakage. Transrectal ultrasonography with enhancing contrast medium (Levovist) is a simple, effective, and minimally invasive examination to evaluate vesicourethral integrity.
- Published
- 2004
41. Dornier lithotripter S - The first 50 treatments in our department
- Author
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C, Di Pietro, S, Micali, S, De Stefani, A, Celia, C, De Carne, and G, Bianchi
- Subjects
Aged, 80 and over ,Adult ,Male ,Ureteral Calculi ,Adolescent ,Equipment Safety ,Dornier Lithotripter S ,Equipment Design ,Middle Aged ,Risk Assessment ,Sensitivity and Specificity ,Radiography ,Cohort Studies ,Kidney Calculi ,Treatment Outcome ,Lithotripsy ,80 and over ,Ambulatory Care ,Humans ,Female ,Child ,Adolescent, Adult, Aged, Aged ,80 and over, Ambulatory Care, Child, Cohort Studies, Equipment Design, Equipment Safety, Female, Follow-Up Studies, Humans, Kidney Calculi, Lithotripsy, Male, Middle Aged, Risk Assessment, Sensitivity and Specificity, Treatment Outcome, Ureteral Calculi ,Aged ,Follow-Up Studies - Abstract
We assessed the short-term efficacy of extracorporeal shockwave lithotripsy with the Dornier Lithotripter S in the treatment of renal and ureteral stones.Between February and April 2003, 32 renal and 19 ureteral stones were treated. Patients were evaluated 1 and 3 months afterwards. Stone size and location, total number of shockwaves and the stone-free rate were taken into consideration.The stone-free rate for ureteral stones was 63% at 1 month and 84.2% at 3 months. The stone-free rate for renal calculi was 75% at 1 month and 87.5% at 3 months. The overall stone-free rate was 70.6% at 1 month and 86.3% at 3 months. Analgesia was necessary in 12 patients (23.5%). No serious complications were seen, except for one steinstrasse.The Dornier Lithotripter S is very effective in the treatment of renal and ureteral calculi.
- Published
- 2004
42. Testicular metastasis of signet ring cell tumour of unknown origin: diagnostic features of a tricky case
- Author
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Giulio Rossi, M. Rivalta, Anna Maria Cesinaro, Giampaolo Bianchi, Maria Chiara Sighinolfi, G. Saredi, N. De Maria, C. Guarasci, F. Fidanza, and S. De Stefani
- Subjects
Oncology ,endocrine system ,medicine.medical_specialty ,Pathology ,endocrine system diseases ,urogenital system ,business.industry ,Signet ring cell ,Urology ,Testicular mass ,General Medicine ,Testicular metastasis ,urologic and male genital diseases ,medicine.disease ,digestive system diseases ,Signet ring cell adenocarcinoma ,Metastasis ,Endocrinology ,Internal medicine ,Signet ring cell carcinoma ,medicine ,Carcinoma ,Adenocarcinoma ,business - Abstract
We introduce the diagnostic complexity of a testicular metastasis by signet ring cell adenocarcinoma of unknown origin. Testicular metastases are a rare event but, particular after 50 years of age, a testicular mass could represent a metastasis.
- Published
- 2011
- Full Text
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43. Treatment of Post-Traumatic Priapism by Means of Autologous Clot Embolization
- Author
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S. De Stefani, M. Capone, and Giorgio Carmignani
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Urology ,medicine.medical_treatment ,Priapism ,Interventional radiology ,medicine.disease ,Complete resolution ,Perineum ,Surgery ,medicine.anatomical_structure ,Penile Diseases ,medicine ,Embolization ,Complication ,business - Abstract
High-flow priapism is a quite uncommon event. The disease should be suspected on the basis of a referred trauma and/or by means of some laboratory findings. Nevertheless selective arteriography remains the only examination able to give us the final diagnosis. Autologous clot embolization allows complete resolution of the problem.
- Published
- 1993
- Full Text
- View/download PDF
44. Urethrocutaneous fistula as a severe complication of treatment for priapism
- Author
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S, De Stefani, G, Savoca, S, Ciampalini, S, Stener, I, GattucCio, and E, Belgrano
- Subjects
Male ,Rupture ,Postoperative Complications ,Urinary Fistula ,Cutaneous Fistula ,Urethral Diseases ,Humans ,Middle Aged ,Priapism ,Achilles Tendon - Published
- 2001
45. [Radial fascio-cutaneous flap of the forearm and myocutaneous gracilis muscle flap in urologic surgery: surgical anatomy and techniques]
- Author
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S, de Stefani, G, Liguori, S, Ciampalini, C, Trombetta, M, Pascone, M, Bertolotto, and E, Belgrano
- Subjects
Adult ,Male ,Humans ,Plastic Surgery Procedures ,Surgical Flaps ,Penis - Abstract
All the concepts and principles commonly espoused in plastic surgery are very useful in urologic reconstructive operations too. Hypospadia's repair, neo-bladder reconstruction, microsurgery of the seminal way require as certain rules as an absolute respect for anatomy, sparing of the finest tissue vascularization and tension free sutures. Pedicled skin flaps harvesting and utilisation are techniques typical of plastic surgery but are also largely used in urologic adult and paediatric surgery. They are adopted for urethral, penile and corpora cavernosa reconstruction. Pedicled flaps are utilised for the closure of large skin defect in case of complicated wound or when an urinary fistula is present, especially after radiotherapy. A perfect knowledge of the flap nourishment and of the method of harvesting is crucial if the best results must be obtained. In our work we describe the surgical technique for the utilisation of gracilis muscle and forearm flap. Special care is taken to the anatomical description.
- Published
- 2000
46. Knotted ureteral catheter in an 83-year-old man: case presentation and urological non-invasive management in the elderly
- Author
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Maria Chiara Sighinolfi, Giampaolo Bianchi, S. De Stefani, M. Rivalta, and Salvatore Micali
- Subjects
Male ,medicine.medical_specialty ,Urology ,medicine.medical_treatment ,Case presentation ,Urinary Diversion ,urologic and male genital diseases ,83-year-old man ,Catheters, Indwelling ,urological non-invasive management ,medicine ,Humans ,ureteral Knotted catheter ,Device Removal ,Upper urinary tract ,Aged, 80 and over ,urogenital system ,business.industry ,Non invasive ,Prostatic Neoplasms ,Stent ,equipment and supplies ,female genital diseases and pregnancy complications ,Surgery ,surgical procedures, operative ,Urinary Bladder Neoplasms ,Stents ,Clinical case ,Ureteral Catheters ,Urinary Catheterization ,business ,Urethral catheter - Abstract
Ureteral catheters are important devices in the management of upper urinary tract obstruction; severe complications due to insertion or stent permanence are unusual. We report the clinical case and management of a knotted ureteral stent in an 83-year-old man.
- Published
- 2009
- Full Text
- View/download PDF
47. [Termino-terminal urethroplasty using microsurgical technique in the treatment of bulbar urethral stenosis: evaluation of long-term results and preservation of potency]
- Author
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S, De Stefani, S, Ciampalini, G, Silvestre, and I, Gattuccio
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Adult ,Male ,Urethral Stricture ,Time Factors ,Adolescent ,Penile Erection ,Anastomosis, Surgical ,Urography ,Middle Aged ,Urodynamics ,Urethra ,Surveys and Questionnaires ,Humans ,Urologic Surgical Procedures ,Follow-Up Studies - Abstract
The Authors report their experience, at long term, on the use of overlap anastomosis sec. Turner Warwick's technique for the treatment of posterior urethral strictures. 12 patients, from 17 to 58 years, were observed. Minimum follow-up was 43.3 months. All patients performed, pre and post-operatively, a retrograde cystogram, an uroflowmetry, a questionnaire to evaluate sexual potency by IIEF and AUA score, and some cases underwent also a cystoscopy post-operatively. Results demonstrated the effectiveness of technique five years later too, which is the period with the greater incidence of recurrences.
- Published
- 1999
48. AMS 800 artificial sphincter: an unusual case of circumscribed peritonitis due to prosthetic reservoir infection
- Author
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S, de Stefani, G, Liguori, S, Ciampalini, and E, Belgrano
- Subjects
Aged, 80 and over ,Male ,Urinary Incontinence ,Humans ,Urinary Sphincter, Artificial ,Peritonitis ,Aged - Abstract
Male urinary incontinence is nowadays a rare event in patients submitted to radical prostatectomy. In these cases, insertion on a hydraulic prosthesis is often the only therapeutical solution. Complications following this type of surgery are rare and when they occur, generally depend on the bacterial contamination of the device which will be "rejected". The cuff is generally the first cause of infection and its prompt removal should solve the problem in the majority of the cases.Herein we report the case of a patient submitted to cuff removal three years earlier who consulted for a symptomless circumscribed peritonitis due to bacterial contamination of the intraperitoneal reservoir.This report emphasizes the need to re-examine the indications for intraperitoneal implantation of the reservoir. Moreover, in case of a three-component prosthetic device, the external components (pump, cylinders and/or cuff) should be removed in a single step, at the same time, in order to avoid future contamination of the internal components.
- Published
- 1999
49. Evaluation of the effects of desmopressin in acute ureteral obstruction
- Author
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U. Moro, P De Antoni, Cesare Selli, Cathryn Anne Scott, S. De Stefani, and A Crisci
- Subjects
Male ,medicine.medical_specialty ,Urology ,Hemodynamics ,Renal function ,urologic and male genital diseases ,Renal Agents ,Pelvis ,Ureter ,medicine ,Pressure ,Animals ,Deamino Arginine Vasopressin ,Renal colic ,Rats, Wistar ,Desmopressin ,business.industry ,Reproducibility of Results ,Cannula ,Surgery ,Rats ,Disease Models, Animal ,Urodynamics ,Blood pressure ,medicine.anatomical_structure ,Acute Disease ,medicine.symptom ,business ,hormones, hormone substitutes, and hormone antagonists ,medicine.drug ,Antidiuretic ,Muscle Contraction ,Ureteral Obstruction - Abstract
Objective: To evaluate the effects of desmopressin on pressure values inside the pelvis and ureter of the rat following acute obstruction. Materials and Methods: By means of a microsurgical technique, 24 male Wistar rats were submitted to ureteral obstruction; pressure inside the ureter was recorded using a cannula and a micrometric glass column. In the treatment group (14 animals) 6 mg/kg of desmopressin were administered 30 min before the beginning of the experiment. Results: Rats pretreated with desmopressin showed a statistically significant reduction in mean intraureteral pressure following acute obstruction (p = 0.05). Conclusions: In Wistar rats desmopressin demonstrated a powerful antidiuretic effect, reducing the intraureteral pressure. The experimental model is useful for a better understanding of physiopathology of renal colic and acute obstruction.
- Published
- 1999
50. 817 Elective segmental ureterectomy for transitional cell carcinoma of the ureter: Long term follow-up in a 73 patients series
- Author
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Andrea Benelli, Mauro Gacci, Andrea Lissiani, M. Ennas, Marco Carini, Sara Benvenuto, G. Bianchi, A. Simonato, F. Gaboardi, Andrea Gregori, Emanuele Belgrano, Virginia Varca, S. De Stefani, M. Rosso, Giampaolo Siena, and G. Carmignani
- Subjects
medicine.medical_specialty ,Series (stratigraphy) ,Transitional cell carcinoma ,Ureter ,medicine.anatomical_structure ,Long term follow up ,Ureterectomy ,business.industry ,Urology ,medicine ,medicine.disease ,business - Published
- 2013
- Full Text
- View/download PDF
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