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Relevance. Tooth splints used to immobilize lower jaw fragments lead to the progression of periodontitis.Purpose. To study changes in periodontal tissues in patients with fractures of the lower jaw during immobilization with dentitional double jaw splints.Materials and methods. Patients with periodontitis during the treatment of fractures of the lower jaw were examined.Results. In patients with periodontitis who have a fracture of the lower jaw, inflammatory and destructive processes in periodontal tissues progress during the immobilization of fragments by the orthopedic method (tooth splints).Conclusion. Comprehensive treatment of periodontitis in fractures of the lower jaw, including dynamic magnetotherapy (DMT) and the treatment of periodontal pockets with liniment of cycloferon, reduces the severity of inflammatory and destructive processes in periodontal tissues.

Relevance: among the directions of modern medicine dental implantology is currently experiencing rapid development. To predict the long-term positive result of surgical treatment, it is important to study the content of Pro- and anti-inflammatory cytokines (IL-8, MCP-1, RAIL, TNF) in the gingival fluid and the validity of the use of immunomodulatory drugs after the installation of dental implants.Purpose – studying the features of changes in the immunoregulatory processes of the mouth cavity when using Imudon medication after dental implantation operation directly into the hole of the removed tooth.Materials and methods: materials, received during the examination of 83 patients, were used for work (42 menand 41 women), with partial secondary adentia, ages 20 to 50, who were treated in dental clinics of “Medstom”, “Masterdent”, and “Tari” (Saratov city).Results: received changes of pro inflammatory and anti-inflammatory levels of cytokines of the gingival sulcus in each examined group, with or without the use of Imudon medication, after implant installation, give the base to believe that after the operation in tissues, surrounding implants, form local changes of immunoregulatory processes.Conclusion: the possibility of early postoperative complications after dental implantation directly into the hole of the removed tooth decreases when prescribing Imudon medication in the first 10 days of the postoperative period.