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1. Optimization of the first CUPID detector module

Author

CUPID Collaboration, K. Alfonso, A. Armatol, C. Augier, F. T. Avignone, O. Azzolini, M. Balata, A. S. Barabash, G. Bari, A. Barresi, D. Baudin, F. Bellini, G. Benato, M. Beretta, M. Bettelli, M. Biassoni, J. Billard, V. Boldrini, A. Branca, C. Brofferio, C. Bucci, J. Camilleri, A. Campani, C. Capelli, S. Capelli, L. Cappelli, L. Cardani, P. Carniti, N. Casali, E. Celi, C. Chang, D. Chiesa, M. Clemenza, I. Colantoni, S. Copello, E. Craft, O. Cremonesi, R. J. Creswick, A. Cruciani, A. D’Addabbo, G. D’Imperio, S. Dabagov, I. Dafinei, F. A. Danevich, M. De Jesus, P. de Marcillac, S. Dell’Oro, S. Di Domizio, S. Di Lorenzo, T. Dixon, V. Dompè, A. Drobizhev, L. Dumoulin, G. Fantini, M. Faverzani, E. Ferri, F. Ferri, F. Ferroni, E. Figueroa-Feliciano, L. Foggetta, J. Formaggio, A. Franceschi, C. Fu, S. Fu, B. K. Fujikawa, A. Gallas, J. Gascon, S. Ghislandi, A. Giachero, A. Gianvecchio, L. Gironi, A. Giuliani, P. Gorla, C. Gotti, C. Grant, P. Gras, P. V. Guillaumon, T. D. Gutierrez, K. Han, E. V. Hansen, K. M. Heeger, D. L. Helis, H. Z. Huang, L. Imbert, J. Johnston, A. Juillard, G. Karapetrov, G. Keppel, H. Khalife, V. V. Kobychev, Yu. G. Kolomensky, S. I. Konovalov, R. Kowalski, T. Langford, M. Lefevre, R. Liu, Y. Liu, P. Loaiza, L. Ma, M. Madhukuttan, F. Mancarella, L. Marini, S. Marnieros, M. Martinez, R. H. Maruyama, Ph. Mas, B. Mauri, D. Mayer, G. Mazzitelli, Y. Mei, S. Milana, S. Morganti, T. Napolitano, M. Nastasi, J. Nikkel, S. Nisi, C. Nones, E. B. Norman, V. Novosad, I. Nutini, T. O’Donnell, E. Olivieri, M. Olmi, J. L. Ouellet, S. Pagan, C. Pagliarone, L. Pagnanini, L. Pattavina, M. Pavan, H. Peng, G. Pessina, V. Pettinacci, C. Pira, S. Pirro, D. V. Poda, O. G. Polischuk, I. Ponce, S. Pozzi, E. Previtali, A. Puiu, S. Quitadamo, A. Ressa, R. Rizzoli, C. Rosenfeld, P. Rosier, J. Scarpaci, B. Schmidt, V. Sharma, V. N. Shlegel, V. Singh, M. Sisti, P. Slocum, D. Speller, P. T. Surukuchi, L. Taffarello, C. Tomei, J. A. Torres, V. I. Tretyak, A. Tsymbaliuk, M. Velazquez, K. J. Vetter, S. L. Wagaarachchi, G. Wang, L. Wang, R. Wang, B. Welliver, J. Wilson, K. Wilson, L. A. Winslow, M. Xue, L. Yan, J. Yang, V. Yefremenko, V. I. Umatov, M. M. Zarytskyy, J. Zhang, A. Zolotarova, and S. Zucchelli

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract CUPID will be a next generation experiment searching for the neutrinoless double $$\beta $$ β decay, whose discovery would establish the Majorana nature of the neutrino. Based on the experience achieved with the CUORE experiment, presently taking data at LNGS, CUPID aims to reach a background free environment by means of scintillating Li $$_{2}$$ 2 $$^{100}$$ 100 MoO $$_4$$ 4 crystals coupled to light detectors. Indeed, the simultaneous heat and light detection allows us to reject the dominant background of $$\alpha $$ α particles, as proven by the CUPID-0 and CUPID-Mo demonstrators. In this work we present the results of the first test of the CUPID baseline module. In particular, we propose a new optimized detector structure and light sensors design to enhance the engineering and the light collection, respectively. We characterized the heat detectors, achieving an energy resolution of (5.9 ± 0.2) keV FWHM at the Q-value of $$^{100}$$ 100 Mo (about 3034 keV). We studied the light collection of the baseline CUPID design with respect to an alternative configuration which features gravity-assisted light detectors’ mounting. In both cases we obtained an improvement in the light collection with respect to past measures and we validated the particle identification capability of the detector, which ensures an $$\alpha $$ α particle rejection higher than 99.9%, fully satisfying the requirements for CUPID.

Published
2022
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2. Search for double-beta decay of $$\mathrm {^{130}Te}$$ 130 Te to the $$0^+$$ 0 + states of $$\mathrm {^{130}Xe}$$ 130 Xe with CUORE

Author

D. Q. Adams, C. Alduino, K. Alfonso, F. T. III Avignone, O. Azzolini, G. Bari, F. Bellini, G. Benato, M. Biassoni, A. Branca, C. Brofferio, C. Bucci, J. Camilleri, A. Caminata, A. Campani, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Cardani, P. Carniti, N. Casali, E. Celi, D. Chiesa, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, A. D’Addabbo, I. Dafinei, C. J. Davis, S. Dell’Oro, S. Di Domizio, V. Dompè, D. Q. Fang, G. Fantini, M. Faverzani, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, S. H. Fu, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, P. Gorla, C. Gotti, T. D. Gutierrez, K. Han, K. M. Heeger, R. G. Huang, H. Z. Huang, J. Johnston, G. Keppel, Yu. G. Kolomensky, C. Ligi, L. Ma, Y. G. Ma, L. Marini, R. H. Maruyama, D. Mayer, Y. Mei, N. Moggi, S. Morganti, T. Napolitano, M. Nastasi, J. Nikkel, C. Nones, E. B. Norman, A. Nucciotti, I. Nutini, T. O’Donnell, J. L. Ouellet, S. Pagan, C. E. Pagliarone, L. Pagnanini, M. Pallavicini, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, C. Pira, S. Pirro, S. Pozzi, E. Previtali, A. Puiu, C. Rosenfeld, C. Rusconi, M. Sakai, S. Sangiorgio, B. Schmidt, N. D. Scielzo, V. Sharma, V. Singh, M. Sisti, D. Speller, P. T. Surukuchi, L. Taffarello, F. Terranova, C. Tomei, K. J. Vetter, M. Vignati, S. L. Wagaarachchi, B. S. Wang, B. Welliver, J. Wilson, K. Wilson, L. A. Winslow, S. Zimmermann, and S. Zucchelli

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The CUORE experiment is a large bolometric array searching for the lepton number violating neutrino-less double beta decay ( $$0\nu \beta \beta $$ 0 ν β β ) in the isotope $$\mathrm {^{130}Te}$$ 130 Te . In this work we present the latest results on two searches for the double beta decay (DBD) of $$\mathrm {^{130}Te}$$ 130 Te to the first $$0^{+}_2$$ 0 2 + excited state of $$\mathrm {^{130}Xe}$$ 130 Xe : the $$0\nu \beta \beta $$ 0 ν β β decay and the Standard Model-allowed two-neutrinos double beta decay ( $$2\nu \beta \beta $$ 2 ν β β ). Both searches are based on a 372.5 kg $$\times $$ × yr TeO $$_2$$ 2 exposure. The de-excitation gamma rays emitted by the excited Xe nucleus in the final state yield a unique signature, which can be searched for with low background by studying coincident events in two or more bolometers. The closely packed arrangement of the CUORE crystals constitutes a significant advantage in this regard. The median limit setting sensitivities at 90% Credible Interval (C.I.) of the given searches were estimated as $$\mathrm {S^{0\nu }_{1/2} = 5.6 \times 10^{24} \, \mathrm {yr}}$$ S 1 / 2 0 ν = 5.6 × 10 24 yr for the $${0\nu \beta \beta }$$ 0 ν β β decay and $$\mathrm {S^{2\nu }_{1/2} = 2.1 \times 10^{24} \, \mathrm {yr}}$$ S 1 / 2 2 ν = 2.1 × 10 24 yr for the $${2\nu \beta \beta }$$ 2 ν β β decay. No significant evidence for either of the decay modes was observed and a Bayesian lower bound at $$90\%$$ 90 % C.I. on the decay half lives is obtained as: $$\mathrm {(T_{1/2})^{0\nu }_{0^+_2} > 5.9 \times 10^{24} \, \mathrm {yr}}$$ ( T 1 / 2 ) 0 2 + 0 ν > 5.9 × 10 24 yr for the $$0\nu \beta \beta $$ 0 ν β β mode and $$\mathrm {(T_{1/2})^{2\nu }_{0^+_2} > 1.3 \times 10^{24} \, \mathrm {yr}}$$ ( T 1 / 2 ) 0 2 + 2 ν > 1.3 × 10 24 yr for the $$2\nu \beta \beta $$ 2 ν β β mode. These represent the most stringent limits on the DBD of $$^{130}$$ 130 Te to excited states and improve by a factor $$\sim 5$$ ∼ 5 the previous results on this process.

Published
2021
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3. Double-beta decay of $$^{130}\hbox {Te}$$ 130Te to the first $$0^+$$ 0+ excited state of $$^{130}\hbox {Xe}$$ 130Xe with CUORE-0

Author

C. Alduino, K. Alfonso, D. R. Artusa, F. T. Avignone III, O. Azzolini, T. I. Banks, G. Bari, J. W. Beeman, F. Bellini, A. Bersani, M. Biassoni, C. Brofferio, C. Bucci, A. Camacho, A. Caminata, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Carbone, L. Cardani, P. Carniti, N. Casali, L. Cassina, D. Chiesa, N. Chott, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, J. S. Cushman, A. D’Addabbo, I. Dafinei, C. J. Davis, S. Dell’Oro, M. M. Deninno, S. Di Domizio, M. L. Di Vacri, A. Drobizhev, D. Q. Fang, M. Faverzani, J. Feintzeig, G. Fernandes, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, L. Gladstone, P. Gorla, C. Gotti, T. D. Gutierrez, E. E. Haller, K. Han, E. Hansen, K. M. Heeger, R. Hennings-Yeomans, K. P. Hickerson, H. Z. Huang, R. Kadel, G. Keppel, Yu. G. Kolomensky, A. Leder, C. Ligi, K. E. Lim, X. Liu, Y. G. Ma, M. Maino, L. Marini, M. Martinez, R. H. Maruyama, Y. Mei, N. Moggi, S. Morganti, P. J. Mosteiro, T. Napolitano, C. Nones, E. B. Norman, A. Nucciotti, T. O’Donnell, F. Orio, J. L. Ouellet, C. E. Pagliarone, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, G. Piperno, C. Pira, S. Pirro, S. Pozzi, E. Previtali, C. Rosenfeld, C. Rusconi, S. Sangiorgio, D. Santone, N. D. Scielzo, V. Singh, M. Sisti, A. R. Smith, L. Taffarello, M. Tenconi, F. Terranova, C. Tomei, S. Trentalange, M. Vignati, S. L. Wagaarachchi, B. S. Wang, H. W. Wang, J. Wilson, L. A. Winslow, T. Wise, A. Woodcraft, L. Zanotti, G. Q. Zhang, B. X. Zhu, S. Zimmermann, and S. Zucchelli

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We report on a search for double beta decay of $$^{130}\hbox {Te}$$ 130Te to the first $$0^{+}$$ 0+ excited state of $$^{130}\hbox {Xe}$$ 130Xe using a $$9.8\,\hbox {kg}\cdot \hbox {yr}$$ 9.8kg·yr exposure of $$^{130}\hbox {Te}$$ 130Te collected with the CUORE-0 experiment. In this work we exploit different topologies of coincident events to search for both the neutrinoless and two-neutrino double beta decay modes. We find no evidence for either mode and place lower bounds on the half-lives: $$T^{0\nu }_{0^+_1}>7.9\cdot 10^{23}\hbox {yr}$$ T01+0ν>7.9·1023yr and $$T^{2\nu }_{0^+_1}>2.4\cdot 10^{23}\hbox {yr}$$ T01+2ν>2.4·1023yr ($$90\%\,\hbox {CL}$$ 90%CL ). Combining our results with those obtained by the CUORICINO experiment, we achieve the most stringent constraints available for these processes: $$T^{0\nu }_{0^+_1}>1.4\cdot 10^{24}\hbox {yr}$$ T01+0ν>1.4·1024yr and $$T^{2\nu }_{0^+_1}>2.5\cdot 10^{23}\hbox {yr}$$ T01+2ν>2.5·1023yr ($$90\%\,\hbox {CL}$$ 90%CL ).

Published
2019
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4. Search of the neutrino-less double beta decay of $$^{82}$$ 82 Se into the excited states of $$^{82}$$ 82 Kr with CUPID-0

Author

O. Azzolini, M. T. Barrera, J. W. Beeman, F. Bellini, M. Beretta, M. Biassoni, E. Bossio, C. Brofferio, C. Bucci, L. Canonica, S. Capelli, L. Cardani, P. Carniti, N. Casali, L. Cassina, M. Clemenza, O. Cremonesi, A. Cruciani, A. D’Addabbo, I. Dafinei, S. Di Domizio, F. Ferroni, L. Gironi, A. Giuliani, P. Gorla, C. Gotti, G. Keppel, M. Martinez, S. Morganti, S. Nagorny, M. Nastasi, S. Nisi, C. Nones, D. Orlandi, L. Pagnanini, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, S. Pirro, S. Pozzi, E. Previtali, A. Puiu, C. Rusconi, K. Schäffner, C. Tomei, M. Vignati, and A. Zolotarova

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The CUPID-0 experiment searches for double beta decay using cryogenic calorimeters with double (heat and light) read-out. The detector, consisting of 24 ZnSe crystals 95$$\%$$ % enriched in $$^{82}$$ 82 Se and two natural ZnSe crystals, started data-taking in 2017 at Laboratori Nazionali del Gran Sasso. We present the search for the neutrino-less double beta decay of $$^{82}$$ 82 Se into the 0$$_1^+$$ 1+ , 2$$_1^+$$ 1+ and 2$$_2^+$$ 2+ excited states of $$^{82}$$ 82 Kr with an exposure of 5.74 kg$$\cdot $$ · yr (2.24$$\times $$ × 10$$^{25}$$ 25 emitters$$\cdot $$ · yr). We found no evidence of the decays and set the most stringent limits on the widths of these processes: $$\varGamma $$ Γ ($$^{82}$$ 82 Se $$\rightarrow ^{82}$$ →82 Kr$$_{0_1^+}$$ 01+ )8.55$$\times $$ × 10$$^{-24}$$ -24 yr$$^{-1}$$ -1 , $$\varGamma $$ Γ ($$^{82}$$ 82 Se $$\rightarrow ^{82}$$ →82 Kr $$_{2_1^+}$$ 21+ )$$\,{

Published
2018
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5. Analysis of cryogenic calorimeters with light and heat read-out for double beta decay searches

Author

O. Azzolini, M. T. Barrera, J. W. Beeman, F. Bellini, M. Beretta, M. Biassoni, E. Bossio, C. Brofferio, C. Bucci, L. Canonica, S. Capelli, L. Cardani, P. Carniti, N. Casali, L. Cassina, M. Clemenza, O. Cremonesi, A. Cruciani, A. D’Addabbo, I. Dafinei, S. Di Domizio, F. Ferroni, L. Gironi, A. Giuliani, P. Gorla, C. Gotti, G. Keppel, M. Martinez, S. Morganti, S. Nagorny, M. Nastasi, S. Nisi, C. Nones, D. Orlandi, L. Pagnanini, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, S. Pirro, S. Pozzi, E. Previtali, A. Puiu, C. Rusconi, K. Schäffner, C. Tomei, M. Vignati, and A. Zolotarova

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The suppression of spurious events in the region of interest for neutrinoless double beta decay will play a major role in next generation experiments. The background of detectors based on the technology of cryogenic calorimeters is expected to be dominated by $$\alpha $$ α particles, that could be disentangled from double beta decay signals by exploiting the difference in the emission of the scintillation light. CUPID-0, an array of enriched Zn$$^{82}$$ 82 Se scintillating calorimeters, is the first large mass demonstrator of this technology. The detector started data-taking in 2017 at the Laboratori Nazionali del Gran Sasso with the aim of proving that dual read-out of light and heat allows for an efficient suppression of the $$\alpha $$ α background. In this paper we describe the software tools we developed for the analysis of scintillating calorimeters and we demonstrate that this technology allows to reach an unprecedented background for cryogenic calorimeters.

Published
2018
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6. CUPID-0: the first array of enriched scintillating bolometers for 0$$\nu \beta \beta $$ νββ decay investigations

Author

O. Azzolini, M. T. Barrera, J. W. Beeman, F. Bellini, M. Beretta, M. Biassoni, C. Brofferio, C. Bucci, L. Canonica, S. Capelli, L. Cardani, P. Carniti, N. Casali, L. Cassina, M. Clemenza, O. Cremonesi, A. Cruciani, A. D’Addabbo, I. Dafinei, S. Di Domizio, F. Ferroni, L. Gironi, A. Giuliani, P. Gorla, C. Gotti, G. Keppel, M. Martinez, S. Morganti, S. Nagorny, M. Nastasi, S. Nisi, C. Nones, D. Orlandi, L. Pagnanini, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, S. Pirro, S. Pozzi, E. Previtali, A. Puiu, F. Reindl, C. Rusconi, K. Schäffner, C. Tomei, M. Vignati, and A. Zolotarova

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The CUPID-0 detector hosted at the Laboratori Nazionali del Gran Sasso, Italy, is the first large array of enriched scintillating cryogenic detectors for the investigation of $$^{82}$$ 82 Se neutrinoless double-beta decay ($$0\nu \beta \beta $$ 0νββ ). CUPID-0 aims at measuring a background index in the region of interest (RoI) for $$0\nu \beta \beta $$ 0νββ at the level of 10$$^{-3}$$ -3 counts/(keV kg years), the lowest value ever measured using cryogenic detectors. CUPID-0 operates an array of Zn$$^{82}$$ 82 Se scintillating bolometers coupled with bolometric light detectors, with a state of the art technology for background suppression and thorough protocols and procedures for the detector preparation and construction. In this paper, the different phases of the detector design and construction will be presented, from the material selection (for the absorber production) to the new and innovative detector structure. The successful construction of the detector lead to promising preliminary detector performance which is discussed here.

Published
2018
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7. Low energy analysis techniques for CUORE

Author

C. Alduino, K. Alfonso, D. R. Artusa, F. T. Avignone, O. Azzolini, G. Bari, J. W. Beeman, F. Bellini, G. Benato, A. Bersani, M. Biassoni, A. Branca, C. Brofferio, C. Bucci, A. Camacho, A. Caminata, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Cardani, P. Carniti, N. Casali, L. Cassina, D. Chiesa, N. Chott, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, J. S. Cushman, A. D’Addabbo, D. D’Aguanno, I. Dafinei, C. J. Davis, S. Dell’Oro, M. M. Deninno, S. Di Domizio, M. L. Di Vacri, A. Drobizhev, D. Q. Fang, M. Faverzani, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, L. Gladstone, P. Gorla, C. Gotti, T. D. Gutierrez, E. E. Haller, K. Han, E. Hansen, K. M. Heeger, R. Hennings-Yeomans, H. Z. Huang, R. Kadel, G. Keppel, Yu. G. Kolomensky, A. Leder, C. Ligi, K. E. Lim, Y. G. Ma, M. Maino, L. Marini, M. Martinez, R. H. Maruyama, Y. Mei, N. Moggi, S. Morganti, P. J. Mosteiro, T. Napolitano, M. Nastasi, C. Nones, E. B. Norman, V. Novati, A. Nucciotti, T. O’Donnell, J. L. Ouellet, C. E. Pagliarone, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, G. Pessina, G. Piperno, C. Pira, S. Pirro, S. Pozzi, E. Previtali, C. Rosenfeld, C. Rusconi, M. Sakai, S. Sangiorgio, D. Santone, B. Schmidt, J. Schmidt, N. D. Scielzo, V. Singh, M. Sisti, A. R. Smith, L. Taffarello, F. Terranova, C. Tomei, M. Vignati, S. L. Wagaarachchi, B. S. Wang, H. W. Wang, B. Welliver, J. Wilson, L. A. Winslow, T. Wise, A. Woodcraft, L. Zanotti, G. Q. Zhang, S. Zimmermann, and S. Zucchelli

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract CUORE is a tonne-scale cryogenic detector operating at the Laboratori Nazionali del Gran Sasso (LNGS) that uses tellurium dioxide bolometers to search for neutrinoless double-beta decay of $$^{130}$$ 130 Te. CUORE is also suitable to search for low energy rare events such as solar axions or WIMP scattering, thanks to its ultra-low background and large target mass. However, to conduct such sensitive searches requires improving the energy threshold to 10 keV. In this paper, we describe the analysis techniques developed for the low energy analysis of CUORE-like detectors, using the data acquired from November 2013 to March 2015 by CUORE-0, a single-tower prototype designed to validate the assembly procedure and new cleaning techniques of CUORE. We explain the energy threshold optimization, continuous monitoring of the trigger efficiency, data and event selection, and energy calibration at low energies in detail. We also present the low energy background spectrum of CUORE-0 below $$60 \, \mathrm {keV}$$ 60 keV . Finally, we report the sensitivity of CUORE to WIMP annual modulation using the CUORE-0 energy threshold and background, as well as an estimate of the uncertainty on the nuclear quenching factor from nuclear recoils inCUORE-0.

Published
2017
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8. The projected background for the CUORE experiment

Author

C. Alduino, K. Alfonso, D. R. Artusa, F. T. Avignone, O. Azzolini, T. I. Banks, G. Bari, J. W. Beeman, F. Bellini, G. Benato, A. Bersani, M. Biassoni, A. Branca, C. Brofferio, C. Bucci, A. Camacho, A. Caminata, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Carbone, L. Cardani, P. Carniti, N. Casali, L. Cassina, D. Chiesa, N. Chott, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, J. S. Cushman, A. D’Addabbo, I. Dafinei, C. J. Davis, S. Dell’Oro, M. M. Deninno, S. Di Domizio, M. L. Di Vacri, A. Drobizhev, D. Q. Fang, M. Faverzani, G. Fernandes, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, L. Gladstone, P. Gorla, C. Gotti, T. D. Gutierrez, E. E. Haller, K. Han, E. Hansen, K. M. Heeger, R. Hennings-Yeomans, K. P. Hickerson, H. Z. Huang, R. Kadel, G. Keppel, Yu. G. Kolomensky, A. Leder, C. Ligi, K. E. Lim, Y. G. Ma, M. Maino, L. Marini, M. Martinez, R. H. Maruyama, Y. Mei, N. Moggi, S. Morganti, P. J. Mosteiro, T. Napolitano, M. Nastasi, C. Nones, E. B. Norman, V. Novati, A. Nucciotti, T. O’Donnell, J. L. Ouellet, C. E. Pagliarone, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, G. Piperno, C. Pira, S. Pirro, S. Pozzi, E. Previtali, C. Rosenfeld, C. Rusconi, M. Sakai, S. Sangiorgio, D. Santone, B. Schmidt, J. Schmidt, N. D. Scielzo, V. Singh, M. Sisti, A. R. Smith, L. Taffarello, M. Tenconi, F. Terranova, C. Tomei, S. Trentalange, M. Vignati, S. L. Wagaarachchi, B. S. Wang, H. W. Wang, B. Welliver, J. Wilson, L. A. Winslow, T. Wise, A. Woodcraft, L. Zanotti, G. Q. Zhang, B. X. Zhu, S. Zimmermann, S. Zucchelli, and M. Laubenstein

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The Cryogenic Underground Observatory for Rare Events (CUORE) is designed to search for neutrinoless double beta decay of $$^{130}$$ 130 Te with an array of 988 TeO $$_2$$ 2 bolometers operating at temperatures around 10 mK. The experiment is currently being commissioned in Hall A of Laboratori Nazionali del Gran Sasso, Italy. The goal of CUORE is to reach a 90% C.L. exclusion sensitivity on the $$^{130}$$ 130 Te decay half-life of 9 $$\times $$ × 10 $$^{25}$$ 25 years after 5 years of data taking. The main issue to be addressed to accomplish this aim is the rate of background events in the region of interest, which must not be higher than 10 $$^{-2}$$ - 2 counts/keV/kg/year. We developed a detailed Monte Carlo simulation, based on results from a campaign of material screening, radioassays, and bolometric measurements, to evaluate the expected background. This was used over the years to guide the construction strategies of the experiment and we use it here to project a background model for CUORE. In this paper we report the results of our study and our expectations for the background rate in the energy region where the peak signature of neutrinoless double beta decay of $$^{130}$$ 130 Te is expected.

Published
2017
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9. CUORE sensitivity to $$0\nu \beta \beta $$ 0 ν β β decay

Author

C. Alduino, K. Alfonso, D. R. Artusa, F. T. Avignone, O. Azzolini, T. I. Banks, G. Bari, J. W. Beeman, F. Bellini, G. Benato, A. Bersani, M. Biassoni, A. Branca, C. Brofferio, C. Bucci, A. Camacho, A. Caminata, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Carbone, L. Cardani, P. Carniti, N. Casali, L. Cassina, D. Chiesa, N. Chott, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, J. S. Cushman, A. D’Addabbo, I. Dafinei, C. J. Davis, S. Dell’Oro, M. M. Deninno, S. Di Domizio, M. L. Di Vacri, A. Drobizhev, D. Q. Fang, M. Faverzani, G. Fernandes, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, L. Gladstone, P. Gorla, C. Gotti, T. D. Gutierrez, E. E. Haller, K. Han, E. Hansen, K. M. Heeger, R. Hennings-Yeomans, K. P. Hickerson, H. Z. Huang, R. Kadel, G. Keppel, Yu. G. Kolomensky, A. Leder, C. Ligi, K. E. Lim, Y. G. Ma, M. Maino, L. Marini, M. Martinez, R. H. Maruyama, Y. Mei, N. Moggi, S. Morganti, P. J. Mosteiro, T. Napolitano, M. Nastasi, C. Nones, E. B. Norman, V. Novati, A. Nucciotti, T. O’Donnell, J. L. Ouellet, C. E. Pagliarone, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, G. Piperno, C. Pira, S. Pirro, S. Pozzi, E. Previtali, C. Rosenfeld, C. Rusconi, M. Sakai, S. Sangiorgio, D. Santone, B. Schmidt, J. Schmidt, N. D. Scielzo, V. Singh, M. Sisti, A. R. Smith, L. Taffarello, M. Tenconi, F. Terranova, C. Tomei, S. Trentalange, M. Vignati, S. L. Wagaarachchi, B. S. Wang, H. W. Wang, B. Welliver, J. Wilson, L. A. Winslow, T. Wise, A. Woodcraft, L. Zanotti, G. Q. Zhang, B. X. Zhu, S. Zimmermann, and S. Zucchelli

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We report a study of the CUORE sensitivity to neutrinoless double beta ( $$0\nu \beta \beta $$ 0 ν β β ) decay. We used a Bayesian analysis based on a toy Monte Carlo (MC) approach to extract the exclusion sensitivity to the $$0\nu \beta \beta $$ 0 ν β β decay half-life ( $$T_{1/2}^{\,0\nu }$$ T 1 / 2 0 ν ) at $$90\%$$ 90 % credibility interval (CI) – i.e. the interval containing the true value of $$T_{1/2}^{\,0\nu }$$ T 1 / 2 0 ν with $$90\%$$ 90 % probability – and the $$3~\sigma $$ 3 σ discovery sensitivity. We consider various background levels and energy resolutions, and describe the influence of the data division in subsets with different background levels. If the background level and the energy resolution meet the expectation, CUORE will reach a $$90\%$$ 90 % CI exclusion sensitivity of $$2\cdot 10^{25}$$ 2 · 10 25 year with 3 months, and $$9\cdot 10^{25}$$ 9 · 10 25 year with 5 years of live time. Under the same conditions, the discovery sensitivity after 3 months and 5 years will be $$7\cdot 10^{24}$$ 7 · 10 24 year and $$4\cdot 10^{25}$$ 4 · 10 25 year, respectively.

Published
2017
Full Text
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10. Characterization and optimization of a β detector for 18F radio-guided surgery

Author

R. Mirabelli, S. Morganti, A. Cartoni, M. De Simoni, R. Faccini, M. Fischetti, A. Giordano, T. Scotognella, E. Solfaroli-Camillocci, and F. Collamati

Subjects
emitter, β detector, Biophysics, β, General Physics and Astronomy, Radio-Guided Surgery, Radiology, Nuclear Medicine and imaging, General Medicine, p-terphenyl, Fluorine-18, ＋
Published
2023

13. 212P Real-world progression-free survival 2 with CDK4/6 inhibitors plus endocrine therapy and subsequent line: Results from the multicenter SISTER study

Author

S. Morganti, S. Gandini, E. Nicolo, E. Zattarin, C. Corti, A. Verrazzo, P.P.M. Berton Giachetti, C. Sposetti, M.G. Razeti, B. Taurelli Salimbeni, L. Boldrini, A. Carnevale Schianca, R. Caputo, C. Vernieri, E. Munzone, M. Lambertini, M. De Laurentiis, G. Viale, G. Curigliano, and C. Criscitiello

Subjects
Cancer Research, Oncology
Published
2023

14. C16 PROPENSITY SCORE COMPARISON OF ELASTIN–BASED AND COLLAGEN–BASED MECHANICAL PROPERTIES OF AORTIC WALL IN BICUSPID VS TRICUSPID AORTIC VALVE PATIENTS UNDERGOING AORTIC SURGERY

Author

P Totaro, F Scocozza, S Morganti, F Auricchio, and S Pelenghi

Subjects
Cardiology and Cardiovascular Medicine
Abstract

Objective Several studies addressed characteristics of aortic wall in patients with bicuspid aortic valve (BAV) compared to those with tricuspid aortic valve (TAV). Different patients population and lack of randomization were the main limitations in many of such studies, focused furthermore, only on ultimate properties (at rupture). In this study we compared mechanical properties in BAV and TAV patients undergoing aortic surgery using propensity score analysis to obtain two homogeneous groups of patients. We also focused on both elastin–based and collagen–based mechanical properties. Methods Among 87 overall patients undergoing surgery of ascending aorta, 26 were selected, following propensity score analysis, and divided in 2 groups according the type of native aortic valve (13 BAV and 13 TAV). Mechanical tests were completed following circumferential and longitudinal force application. 137 cumulative tests were accepted (93 from anterior aortic wall). Aortic wall strain (marker of elasticity) and aortic wall stress (marker of strength) were measured either in the Elastin–based (initial) distension and in the Collagen–based ultimate distension (until rupture). Results Cumulative comparison of specimens thickness confirmed that anterior aortic wall is thinner in BAV patients. Aortic wall thickness, however was not correlated to any of mechanical tests in Elastin–based or Collagen–based distensions. Aortic wall elasticity and strength (applying either longitudinal and circumferential force) were not different in BAV compared to TAV patients. Initial and ultimate elasticity were significantly correlated either applying circumferential and longitudinal force. Direct correlation between initial and ultimate strength, on other hands, was showed only in BAV patients when a longitudinal force was applied. Conclusions We clearly showed that, in dilated aorta, anterior wall is thinner in case of BAV compared to TAV. Our study, furthermore, confirms that mechanical properties of aortic wall in BAV patients are no impaired, compared to an homogeneous group of TAV patients, neither in initial or ultimate tests. Elastin–based and collagen–based aortic wall mechanical properties (under circumferential force) are directly correlated regardless BAV presence. Lack of correlation between initial and ultimate strenght in TAV patients, under a longitudinal force, needs further evaluation as it could be related to an increased frailty of aortic wall in such conditions.

Published
2022

17. How I treat HER2-positive early breast cancer: how long adjuvant trastuzumab is needed?

Author

S. Morganti, G. Bianchini, A. Giordano, M. Giuliano, G. Curigliano, and C. Criscitiello

Subjects
Cancer Research, Oncology, Chemotherapy, Adjuvant, Receptor, ErbB-2, Humans, Breast Neoplasms, Female, Trastuzumab, Disease-Free Survival
Abstract

Since its first approval in 2006, 1 year of adjuvant trastuzumab has been the standard of care for early-stage HER2-positive breast cancer. Nevertheless, the optimal duration of adjuvant trastuzumab was uncertain, and the standard 12-month duration has been questioned by a number of different trials. Although most of these studies were formally negative, a patient-level meta-analysis presented at the 2021 European Society for Medical Oncology (ESMO) meeting first showed the non-inferiority of 6-month trastuzumab. Through this review, we sought to take a closer look at the meta-analysis and the included trials to explain why we believe that non-inferiority should be interpreted with caution. Indeed, here we underline how the meta-analysis' results were mainly driven by the PERSEPHONE study, an old trial that tested non-standard chemo-trastuzumab regimens in a relatively low-risk population with doubtful endpoints. In summary, considering all the limitations of this analysis and the increasing use of effective anthracycline-free de-escalation strategies, we are convinced that 1-year trastuzumab should remain the standard of care.

Published
2022

18. CUORE opens the door to tonne-scale cryogenics experiments

Author

L. Canonica, L. Marini, Kevin Hickerson, J. Schmidt, Massimiliano Clemenza, Carlo Cosmelli, S. Copello, L. Gladstone, M. Guerzoni, L. Ma, J. Johnston, A. Leder, M. Iannone, Irene Nutini, Paolo Carniti, Vladimir Datskov, R. J. Creswick, M. M. Deninno, G. Fantini, F. Bellini, I. C. Bandac, Yu-Gang Ma, D. Santone, V. Sharma, C. Brofferio, P. J. Mosteiro, A. Caminata, Ezio Previtali, B. Welliver, Evelyn Ferri, H. Z. Huang, G. Keppel, K. E. Lim, X. G. Cao, F. Bragazzi, Ettore Fiorini, V. Novati, C. Rusconi, N. Chott, T. Wise, C. Crescentini, R. Gaigher, L. Zanotti, Andrea Giachero, C. Maiano, N. Moggi, C. Martinez Amaya, S. S. Nagorny, A. Pelosi, G. Piperno, D. Q. Adams, L. Risegari, K. Alfonso, F. Terranova, Davide Chiesa, C. Rosenfeld, Deqing Fang, S. Pagan, S. Dell'Oro, M. L. Di Vacri, D. Mayer, Samuele Sangiorgio, Stefano Nisi, P. T. Surukuchi, S. Morganti, S. Zucchelli, J. Camilleri, A. Nucciotti, M. Sisti, P. Gorla, E. V. Hansen, F. Ferroni, C. Tomei, Elena Sala, L. Ioannucci, D. Speller, F. Alessandria, M. I. Martínez, Eugene E. Haller, C. Alduino, F. Rimondi, G. Ceruti, K. Wilson, L. Taffarello, Marisa Pedretti, R. Hennings-Yeomans, S. Pirro, Carlo Ligi, M. Faverzani, M. Beretta, Y. Mei, M. Tessaro, Jeffrey W. Beeman, M. Capodiferro, A. Bersani, N. D. Scielzo, M. Barucci, L. Cappelli, D. Biare, C. J. Davis, A. Camacho, Jonathan Ouellet, D. Conventi, J. Wallig, K. M. Heeger, L. Pagnanini, A. Giuliani, G. Bari, M. Cariello, Lindley Winslow, A. Campani, S. L. Wagaarachchi, M. Maino, Guoqiang Zhang, M. Carrettoni, R. Mazza, A. Branca, A. Bryant, J. Nikkel, C. Pira, H.W. Wang, M. Perego, T. I. Banks, S. Zimmermann, Ke Han, Reina H. Maruyama, S. Ghislandi, T. O'Donnell, S. Di Domizio, Simone Capelli, R. W. Kadel, Stuart J. Freedman, G. Ventura, A. Drobizhev, C. Bulfon, C. Zarra, Laura Cardani, V. Dompè, M. Balata, L. Di Paolo, A. D'Addabbo, L. Pattavina, B. K. Fujikawa, Stefano Pozzi, Alan R. Smith, D. Orlandi, Larissa M. Ejzak, M. Vignati, B. X. Zhu, V. Pettinacci, L. Kogler, E. Celi, L. Tatananni, S.H. Fu, E. Andreotti, M. A. Franceschi, R. Cereseto, I. Dafinei, M. Sakai, D. D'Aguanno, F. Stivanello, R. G. Huang, D. Schaeffer, C. Guandalini, F. Orio, Vasundhara Singh, B. Schmidt, B. S. Wang, O. Azzolini, Kai Vetter, M. Olcese, Jeremy S. Cushman, V. Palmieri, Eric B. Norman, M. Guetti, T. Napolitano, M. Biassoni, F. Del Corso, R. Faccini, Giovanni Benato, A. Buccheri, C. Salvioni, Yu. G. Kolomensky, R. Pedrotta, Lorenzo Cassina, C. Nones, A. Puiu, Marco Pallavicini, S. Quitadamo, G. Pessina, James R. Wilson, R. Liu, Massimiliano Nastasi, M. Pavan, E. Olivieri, L. Gironi, F. T. Avignone, Claudio Gotti, N. Casali, F. Reindl, Oliviero Cremonesi, J. Goett, M. Tenconi, C. Pagliarone, C. Rossi, A. Chiarini, C. Bucci, T. D. Gutierrez, Adams, D, Alduino, C, Alessandria, F, Alfonso, K, Andreotti, E, Avignone, F, Azzolini, O, Balata, M, Bandac, I, Banks, T, Bari, G, Barucci, M, Beeman, J, Bellini, F, Benato, G, Beretta, M, Bersani, A, Biare, D, Biassoni, M, Bragazzi, F, Branca, A, Brofferio, C, Bryant, A, Buccheri, A, Bucci, C, Bulfon, C, Camacho, A, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Capodiferro, M, Cappelli, L, Cardani, L, Cariello, M, Carniti, P, Carrettoni, M, Casali, N, Cassina, L, Celi, E, Cereseto, R, Ceruti, G, Chiarini, A, Chiesa, D, Chott, N, Clemenza, M, Conventi, D, Copello, S, Cosmelli, C, Cremonesi, O, Crescentini, C, Creswick, R, Cushman, J, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Datskov, V, Davis, C, Corso, F, Dell'Oro, S, Deninno, M, Di Domizio, S, Dompe, V, Di Vacri, M, Di Paolo, L, Drobizhev, A, Ejzak, L, Faccini, R, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fu, S, Fujikawa, B, Gaigher, R, Ghislandi, S, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Goett, J, Gorla, P, Gotti, C, Guandalini, C, Guerzoni, M, Guetti, M, Gutierrez, T, Haller, E, Han, K, Hansen, E, Heeger, K, Hennings-Yeomans, R, Hickerson, K, Huang, R, Huang, H, Iannone, M, Ioannucci, L, Johnston, J, Kadel, R, Keppel, G, Kogler, L, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Liu, R, Ma, L, Ma, Y, Maiano, C, Maino, M, Marini, L, Martinez, M, Amaya, C, Maruyama, R, Mayer, D, Mazza, R, Mei, Y, Moggi, N, Morganti, S, Mosteiro, P, Nagorny, S, Napolitano, T, Nastasi, M, Nikkel, J, Nisi, S, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Olcese, M, Olivieri, E, Orio, F, Orlandi, D, Ouellet, J, Pagan, S, Pagliarone, C, Pagnanini, L, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pedretti, M, Pedrotta, R, Pelosi, A, Perego, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Reindl, F, Rimondi, F, Risegari, L, Rosenfeld, C, Rossi, C, Rusconi, C, Sakai, M, Sala, E, Salvioni, C, Sangiorgio, S, Santone, D, Schaeffer, D, Schmidt, B, Schmidt, J, Scielzo, N, Sharma, V, Singh, V, Sisti, M, Smith, A, Speller, D, Stivanello, F, Surukuchi, P, Taffarello, L, Tatananni, L, Tenconi, M, Terranova, F, Tessaro, M, Tomei, C, Ventura, G, Vetter, K, Vignati, M, Wagaarachchi, S, Wallig, J, Wang, B, Wang, H, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zarra, C, Zhang, G, Zhu, B, Zimmermann, S, Zucchelli, S, Adams D.Q., Alduino C., Alessandria F., Alfonso K., Andreotti E., Avignone F.T., Azzolini O., Balata M., Bandac I., Banks T.I., Bari G., Barucci M., Beeman J.W., Bellini F., Benato G., Beretta M., Bersani A., Biare D., Biassoni M., Bragazzi F., Branca A., Brofferio C., Bryant A., Buccheri A., Bucci C., Bulfon C., Camacho A., Camilleri J., Caminata A., Campani A., Canonica L., Cao X.G., Capelli S., Capodiferro M., Cappelli L., Cardani L., Cariello M., Carniti P., Carrettoni M., Casali N., Cassina L., Celi E., Cereseto R., Ceruti G., Chiarini A., Chiesa D., Chott N., Clemenza M., Conventi D., Copello S., Cosmelli C., Cremonesi O., Crescentini C., Creswick R.J., Cushman J.S., D'Addabbo A., D'Aguanno D., Dafinei I., Datskov V., Davis C.J., Del Corso F., Dell'Oro S., Deninno M.M., Di Domizio S., Dompe V., Di Vacri M.L., Di Paolo L., Drobizhev A., Ejzak L., Faccini R., Fang D.Q., Fantini G., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M.A., Freedman S.J., Fu S.H., Fujikawa B.K., Gaigher R., Ghislandi S., Giachero A., Gironi L., Giuliani A., Gladstone L., Goett J., Gorla P., Gotti C., Guandalini C., Guerzoni M., Guetti M., Gutierrez T.D., Haller E.E., Han K., Hansen E.V., Heeger K.M., Hennings-Yeomans R., Hickerson K.P., Huang R.G., Huang H.Z., Iannone M., Ioannucci L., Johnston J., Kadel R., Keppel G., Kogler L., Kolomensky Y.G., Leder A., Ligi C., Lim K.E., Liu R., Ma L., Ma Y.G., Maiano C., Maino M., Marini L., Martinez M., Amaya C.M., Maruyama R.H., Mayer D., Mazza R., Mei Y., Moggi N., Morganti S., Mosteiro P.J., Nagorny S.S., Napolitano T., Nastasi M., Nikkel J., Nisi S., Nones C., Norman E.B., Novati V., Nucciotti A., Nutini I., O'Donnell T., Olcese M., Olivieri E., Orio F., Orlandi D., Ouellet J.L., Pagan S., Pagliarone C.E., Pagnanini L., Pallavicini M., Palmieri V., Pattavina L., Pavan M., Pedretti M., Pedrotta R., Pelosi A., Perego M., Pessina G., Pettinacci V., Piperno G., Pira C., Pirro S., Pozzi S., Previtali E., Puiu A., Quitadamo S., Reindl F., Rimondi F., Risegari L., Rosenfeld C., Rossi C., Rusconi C., Sakai M., Sala E., Salvioni C., Sangiorgio S., Santone D., Schaeffer D., Schmidt B., Schmidt J., Scielzo N.D., Sharma V., Singh V., Sisti M., Smith A.R., Speller D., Stivanello F., Surukuchi P.T., Taffarello L., Tatananni L., Tenconi M., Terranova F., Tessaro M., Tomei C., Ventura G., Vetter K.J., Vignati M., Wagaarachchi S.L., Wallig J., Wang B.S., Wang H.W., Welliver B., Wilson J., Wilson K., Winslow L.A., Wise T., Zanotti L., Zarra C., Zhang G.Q., Zhu B.X., Zimmermann S., Zucchelli S., Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, and CUORE

Subjects
Cryostat, Nuclear and High Energy Physics, Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, FOS: Physical sciences, Cryogenic temperatures, Dilution refrigerator, Low temperature calorimeter, Neutrinoless double beta decay, Rare event searches, Ton-scale detector, Cryogenic temperatures, Neutrinoless double beta decay, Dilution refrigerator, Ton-scale detector, Low temperature calorimeter, Rare event searches, cryogenics, CUORE performance, Cryogenics, Rare event searche, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 7. Clean energy, 01 natural sciences, CUORE, double-beta decay: (0neutrino), Double beta decay, 0103 physical sciences, Cryogenic particle detectors, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Nuclear Experiment (nucl-ex), Aerospace engineering, 010306 general physics, Nuclear Experiment, activity report, Physics, 010308 nuclear & particles physics, business.industry, Astrophysics::Instrumentation and Methods for Astrophysics, Cryogenic temperature, Instrumentation and Detectors (physics.ins-det), CUORE performance, Semiconductor detector, cryogenics: design, cryogenics, Neutrino, business, performance
Abstract

The past few decades have seen major developments in the design and operation of cryogenic particle detectors. This technology offers an extremely good energy resolution - comparable to semiconductor detectors - and a wide choice of target materials, making low temperature calorimetric detectors ideal for a variety of particle physics applications. Rare event searches have continued to require ever greater exposures, which has driven them to ever larger cryogenic detectors, with the CUORE experiment being the first to reach a tonne-scale, mK-cooled, experimental mass. CUORE, designed to search for neutrinoless double beta decay, has been operational since 2017 at a temperature of about 10 mK. This result has been attained by the use of an unprecedentedly large cryogenic infrastructure called the CUORE cryostat: conceived, designed and commissioned for this purpose. In this article the main characteristics and features of the cryogenic facility developed for the CUORE experiment are highlighted. A brief introduction of the evolution of the field and of the past cryogenic facilities are given. The motivation behind the design and development of the CUORE cryogenic facility is detailed as are the steps taken toward realization, commissioning, and operation of the CUORE cryostat. The major challenges overcome by the collaboration and the solutions implemented throughout the building of the cryogenic facility will be discussed along with the potential improvements for future facilities. The success of CUORE has opened the door to a new generation of large-scale cryogenic facilities in numerous fields of science. Broader implications of the incredible feat achieved by the CUORE collaboration on the future cryogenic facilities in various fields ranging from neutrino and dark matter experiments to quantum computing will be examined., Comment: 45 pages, 14 figures

Published
2022

19. Expected sensitivity to $^{128}$Te neutrinoless double beta decay with the CUORE TeO$_2$ cryogenic bolometers

Author

V. Dompè, D. Q. Adams, C. Alduino, K. Alfonso, F. T. Avignone, O. Azzolini, G. Bari, F. Bellini, G. Benato, M. Beretta, M. Biassoni, A. Branca, C. Brofferio, C. Bucci, J. Camilleri, A. Caminata, A. Campani, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Cardani, P. Carniti, N. Casali, E. Celi, D. Chiesa, M. Clemenza, S. Copello, O. Cremonesi, R. J. Creswick, A. D’Addabbo, I. Dafinei, S. Dell’Oro, S. Di Domizio, S. Di Lorenzo, D. Q. Fang, G. Fantini, M. Faverzani, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, S. H. Fu, B. K. Fujikawa, S. Ghislandi, A. Giachero, L. Gironi, A. Giuliani, P. Gorla, C. Gotti, T. D. Gutierrez, K. Han, E. V. Hansen, K. M. Heeger, R. G. Huang, H. Z. Huang, J. Johnston, G. Keppel, Yu G. Kolomensky, R. Kowalski, C. Ligi, R. Liu, L. Ma, Y. G. Ma, L. Marini, R. H. Maruyama, D. Mayer, Y. Mei, N. Moggi, S. Morganti, T. Napolitano, M. Nastasi, J. Nikkel, C. Nones, E. B. Norman, A. Nucciotti, I. Nutini, T. O’Donnell, M. Olmi, J. L. Ouellet, S. Pagan, C. E. Pagliarone, L. Pagnanini, M. Pallavicini, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, C. Pira, S. Pirro, S. Pozzi, E. Previtali, A. Puiu, S. Quitadamo, A. Ressa, C. Rosenfeld, C. Rusconi, M. Sakai, S. Sangiorgio, B. Schmidt, N. D. Scielzo, V. Sharma, V. Singh, M. Sisti, D. Speller, P. T. Surukuchi, L. Taffarello, F. Terranova, C. Tomei, K. J. Vetter, M. Vignati, S. L. Wagaarachchi, B. S. Wang, B. Welliver, J. Wilson, K. Wilson, L. A. Winslow, S. Zimmermann, S. Zucchelli, Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Dompe, V, Adams, D, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Beretta, M, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chiesa, D, Clemenza, M, Copello, S, Cremonesi, O, Creswick, R, D'Addabbo, A, Dafinei, I, Dell'Oro, S, Di Domizio, S, Di Lorenzo, S, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fu, S, Fujikawa, B, Ghislandi, S, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Hansen, E, Heeger, K, Huang, R, Huang, H, Johnston, J, Keppel, G, Kolomensky, Y, Kowalski, R, Ligi, C, Liu, R, Ma, L, Ma, Y, Marini, L, Maruyama, R, Mayer, D, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, E, Nucciotti, A, Nutini, I, O'Donnell, T, Olmi, M, Ouellet, J, Pagan, S, Pagliarone, C, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Ressa, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, N, Sharma, V, Singh, V, Sisti, M, Speller, D, Surukuchi, P, Taffarello, L, Terranova, F, Tomei, C, Vetter, K, Vignati, M, Wagaarachchi, S, Wang, B, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Zimmermann, S, Zucchelli, S, Adams, DQ, Avignone, FT, Cao, XG, Creswick, RJ, Fang, DQ, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Gutierrez, TD, Hansen, EV, Heeger, KM, Huang, RG, Huang, HZ, Kolomensky, YG, Ma, YG, Maruyama, RH, Norman, EB, Ouellet, JL, Pagliarone, CE, Scielzo, ND, Surukuchi, PT, Vetter, KJ, Wagaarachchi, SL, Wang, BS, and Winslow, LA

Subjects
CUORE, Physics::Instrumentation and Detectors, Astrophysics::Instrumentation and Methods for Astrophysics, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], Condensed Matter Physics, Cryogenic bolometer, Atomic and Molecular Physics, and Optics, CUORE, Cryogenic Bolometers, Cryogenic bolometers, General Materials Science, High Energy Physics::Experiment, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Neutrinoless double beta decay, Tellurium, Nuclear Experiment, 128-Te
Abstract

The CUORE experiment is a ton-scale array of $$\hbox {TeO}_2$$ TeO 2 cryogenic bolometers located at the underground Laboratori Nazionali del Gran Sasso of Istituto Nazionale di Fisica Nucleare (INFN), in Italy. The CUORE detector consists of 988 crystals operated as source and detector at a base temperature of $$\sim 10$$ ∼ 10 mK. Such cryogenic temperature is reached and maintained by means of a custom built cryogen-free dilution cryostat, designed with the aim of minimizing the vibrational noise and the environmental radioactivity. The primary goal of CUORE is the search for neutrinoless double beta decay of $$^{130}\hbox {Te}$$ 130 Te , but thanks to its large target mass and ultra-low background it is suitable for the study of other rare processes as well, such as the neutrinoless double beta decay of $$^{128}\hbox {Te}$$ 128 Te . This tellurium isotope is an attractive candidate for the search of this process, due to its high natural isotopic abundance of 31.75%. The transition energy at (866.7 ± 0.7) keV lies in a highly populated region of the energy spectrum, dominated by the contribution of the two-neutrino double beta decay of $$^{130}\hbox {Te}$$ 130 Te . As the first ton-scale infrastructure operating cryogenic $$\hbox {TeO}_2$$ TeO 2 bolometers in stable conditions, CUORE is able to achieve a factor $$>10$$ > 10 higher sensitivity to the neutrinoless double beta decay of this isotope with respect to past direct experiments.

Published
2021

20. Searching for Neutrinoless Double-Beta Decay of 130Te with CUORE

Author

D. R. Artusa, F. T. Avignone, O. Azzolini, M. Balata, T. I. Banks, G. Bari, J. Beeman, F. Bellini, A. Bersani, M. Biassoni, C. Brofferio, C. Bucci, X. Z. Cai, A. Camacho, L. Canonica, X. G. Cao, S. Capelli, L. Carbone, L. Cardani, M. Carrettoni, N. Casali, D. Chiesa, N. Chott, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, I. Dafinei, A. Dally, V. Datskov, A. De Biasi, M. M. Deninno, S. Di Domizio, M. L. di Vacri, L. Ejzak, D. Q. Fang, H. A. Farach, M. Faverzani, G. Fernandes, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, J. Goett, P. Gorla, C. Gotti, T. D. Gutierrez, E. E. Haller, K. Han, K. M. Heeger, R. Hennings-Yeomans, H. Z. Huang, R. Kadel, K. Kazkaz, G. Keppel, Yu. G. Kolomensky, Y. L. Li, C. Ligi, X. Liu, Y. G. Ma, C. Maiano, M. Maino, M. Martinez, R. H. Maruyama, Y. Mei, N. Moggi, S. Morganti, T. Napolitano, S. Nisi, C. Nones, E. B. Norman, A. Nucciotti, T. O’Donnell, F. Orio, D. Orlandi, J. L. Ouellet, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, M. Pedretti, G. Pessina, V. Pettinacci, G. Piperno, C. Pira, S. Pirro, E. Previtali, V. Rampazzo, C. Rosenfeld, C. Rusconi, E. Sala, S. Sangiorgio, N. D. Scielzo, M. Sisti, A. R. Smith, L. Taffarello, M. Tenconi, F. Terranova, W. D. Tian, C. Tomei, S. Trentalange, G. Ventura, M. Vignati, B. S. Wang, H. W. Wang, L. Wielgus, J. Wilson, L. A. Winslow, T. Wise, A. Woodcraft, L. Zanotti, C. Zarra, B. X. Zhu, and S. Zucchelli

Subjects
Physics, QC1-999
Abstract

Neutrinoless double-beta (0νββ) decay is a hypothesized lepton-number-violating process that offers the only known means of asserting the possible Majorana nature of neutrino mass. The Cryogenic Underground Observatory for Rare Events (CUORE) is an upcoming experiment designed to search for 0νββ decay of 130Te using an array of 988 TeO2 crystal bolometers operated at 10 mK. The detector will contain 206 kg of 130Te and have an average energy resolution of 5 keV; the projected 0νββ decay half-life sensitivity after five years of livetime is 1.6 × 1026 y at 1σ (9.5 × 1025 y at the 90% confidence level), which corresponds to an upper limit on the effective Majorana mass in the range 40–100 meV (50–130 meV). In this paper, we review the experimental techniques used in CUORE as well as its current status and anticipated physics reach.

Published
2015
Full Text
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22. Measurement of the 2νββ Decay Half-Life of Te130 with CUORE

Author

V. Sharma, D. Speller, Deqing Fang, S. Morganti, J. Nikkel, S. H. Fu, P. T. Surukuchi, S. Zimmermann, Carlo Ligi, R. J. Creswick, A. Campani, L. Gironi, I. Nutini, C. Rosenfeld, J. Camilleri, Oliviero Cremonesi, Kai Vetter, P. Gorla, F. Ferroni, C. Tomei, Massimiliano Clemenza, Carlo Cosmelli, Monica Sisti, F. T. Avignone, B. S. Wang, A. Giuliani, Emanuele Ferri, C. Pagliarone, N. D. Scielzo, C. Brofferio, L. Pattavina, C. J. Davis, Silvia Capelli, S. Pozzi, F. Terranova, C. Nones, A. Puiu, Massimiliano Nastasi, S. Di Domizio, K. Wilson, Davide Chiesa, Lucia Canonica, A. Caminata, Ezio Previtali, Marco Pallavicini, C. Rusconi, B. Welliver, V. Dompè, F. Bellini, Jonathan Ouellet, G. Bari, H. Z. Huang, S. Pagan, Y. Mei, A. D'Addabbo, C. Bucci, L. Marini, T. D. Gutierrez, T. O'Donnell, J. Johnston, S. Copello, N. Moggi, Laura Cardani, Yu. G. Kolomensky, Luigi Cappelli, B. K. Fujikawa, Xiangyu Cao, G. Keppel, Samuele Sangiorgio, K. M. Heeger, A. Nucciotti, C. Alduino, S. Pirro, B. Schmidt, Stefano Zucchelli, S. Dell'Oro, Ke Han, Paolo Carniti, Reina H. Maruyama, Claudio Gotti, Stuart J. Freedman, M. Sakai, O. Azzolini, T. Napolitano, M. Pavan, N. Casali, James R. Wilson, G. Pessina, S. L. Wagaarachchi, V. Pettinacci, M. Vignati, M. Biassoni, I. Dafinei, E. Fiorini, Giovanni Benato, Yudi Ma, L. Pagnanini, Eric B. Norman, L. Taffarello, D. Q. Adams, K. Alfonso, D. Mayer, M. Faverzani, Lindley Winslow, Virendra Singh, L. Ma, C. Pira, G. Fantini, R. G. Huang, A. Branca, M. A. Franceschi, and A. Giachero

Subjects
Physics, Nuclear physics, CUORE, Double beta decay, 0103 physical sciences, General Physics and Astronomy, Half-life, High Energy Physics::Experiment, 010306 general physics, 01 natural sciences, Spectral line
Abstract

We measured two-neutrino double beta decay of $^{130}$Te using an exposure of 300.7 kg$\cdot$yr accumulated with the CUORE detector. Using a Bayesian analysis to fit simulated spectra to experimental data, it was possible to disentangle all the major background sources and precisely measure the two-neutrino contribution. The half-life is in agreement with past measurements with a strongly reduced uncertainty: $T^{2\nu}_{1/2} = 7.71^{+0.08}_{-0.06}\mathrm{(stat.)}^{+0.12}_{-0.15}\mathrm{(syst.)}\times10^{20}$ yr. This measurement is the most precise determination of the $^{130}$Te 2$\nu\beta\beta$ decay half-life to date.

Published
2021

23. The β- radio-guided surgery: Method to estimate the minimum injectable activity from ex-vivo test

Author

Bianca Pollo, V. Bocci, Monica Patanè, Marzia Colandrea, C. Mancini Terracciano, Marta Cremonesi, Chiara Maria Grana, Stefano Papi, Paolo Ferroli, Marco Schiariti, Francesco Collamati, R. Mirabelli, F. Ghielmetti, Giacomo Traini, S. Morganti, Riccardo Faccini, A. Russomando, M. Marafini, R. Ghisini, Guido Pedroli, Mahila Ferrari, and E. Solfaroli Camillocci

Subjects
Novel technique, medicine.medical_specialty, business.industry, Biophysics, Low activity, General Physics and Astronomy, Standardized uptake value, General Medicine, medicine.disease, 030218 nuclear medicine & medical imaging, Surgery, Meningioma, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, medicine, Feature based, Low dose ct, Radiology, Nuclear Medicine and imaging, business, Intraoperative imaging, Ex vivo
Abstract

Purpose Radio-guided surgery with β - decays is a novel technique under investigation. One of the main advantages is its capability to detect small ( ⩽ 0.1 ml) samples after injecting the patient with low activity of radiopharmaceutical. This paper presents an experimental method to quantify this feature based on ex-vivo tests on specimens from meningioma patients. Methods Patients were enrolled on the basis of the standard uptake value (SUV) and the tumour-to-non-tumour activity ratio (TNR) resulted from 68Ga-DOTATOC PET exams. After injecting the patients with 93–167 MBq of 90Y-DOTATOC, 26 samples excised during surgery were analyzed with a β - probe. The radioactivity expected on the neoplastic specimens was estimated according to the SUV found in the PET scan and the correlation with the measured counts was studied. The doses to surgeon and medical personnel were also evaluated. Results Even injecting as low as 1.4 MBq/kg of radiotracer, tumour residuals of 0.1 ml can be detected. A negligible dose to the medical personnel was confirmed. Conclusions Radio-guided surgery with β - decays is a feasible technique with a low radiation dose for both personnel and patient, in particular if the patient is injected with the minimum required activity. A correlation greater than 80% was observed between the measured counts and the expected activity for the lesion samples based on the individual SUV and the TNR. This makes identifiable the minimum injectable radiotracer activity for cases where 90Y is the utilized radionuclide.

Published
2019

25. Search for Double-Beta Decay of $\mathrm{^{130}Te}$ to the $0^+$ States of $\mathrm{^{130}Xe}$ with CUORE

Author

Davide Chiesa, S. Di Domizio, Laura Cardani, B. K. Fujikawa, Stefano Pozzi, M. Vignati, Massimiliano Clemenza, Carlo Cosmelli, A. Giuliani, Monica Sisti, C. Pagliarone, V. Sharma, S. Zimmermann, A. Branca, Deqing Fang, S. Dell'Oro, B. Schmidt, L. Pattavina, L. Pagnanini, B. S. Wang, C. Brofferio, Marco Pallavicini, Lindley Winslow, F. Terranova, S. Morganti, O. Azzolini, S. Copello, S. Pagan, Kai Vetter, G. Pessina, Paolo Carniti, C. Rusconi, Carlo Ligi, L. Taffarello, L. Ma, Virendra Singh, Yudi Ma, H. Z. Huang, C. Rosenfeld, S. Pirro, A. Campani, C. Pira, Ettore Fiorini, S. L. Wagaarachchi, Andrea Giachero, P. Gorla, F. Ferroni, J. Camilleri, Xiangyu Cao, C. Tomei, Ke Han, Reina H. Maruyama, Stuart J. Freedman, L. Canonica, L. Marini, D. Q. Adams, Simone Capelli, K. Alfonso, G. Keppel, D. Speller, D. Mayer, C. J. Davis, Y. Mei, C. Nones, A. Puiu, I. Dafinei, Irene Nutini, J. Johnston, V. Pettinacci, A. Caminata, V. Dompè, A. D'Addabbo, J. Nikkel, G. Fantini, K. M. Heeger, Ezio Previtali, P. T. Surukuchi, T. O'Donnell, Yu. G. Kolomensky, N. D. Scielzo, R. G. Huang, B. Welliver, K. Wilson, Jonathan Ouellet, G. Bari, E. Celi, M. A. Franceschi, S. Zucchelli, M. Faverzani, Evelyn Ferri, N. Moggi, Eric B. Norman, L. Cappelli, M. Sakai, T. Napolitano, Samuele Sangiorgio, Oliviero Cremonesi, A. Nucciotti, M. Biassoni, C. Alduino, Claudio Gotti, N. Casali, Giovanni Benato, C. Bucci, T. D. Gutierrez, L. Gironi, F. T. Avignone, F. Bellini, R. J. Creswick, M. Pavan, Massimiliano Nastasi, James R. Wilson, S. H. Fu, Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, CUORE, and Département de Physique des Particules (ex SPP) (DPhP)

Subjects
Particle physics, experimental methods, Physics and Astronomy (miscellaneous), FOS: Physical sciences, Dirac Neutrino, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], Neutrinoless Double Beta Decay, 7. Clean energy, 01 natural sciences, Bayesian, decay modes, crystal, CUORE, background: low, bolometer, Double beta decay, Neutrino, 0103 physical sciences, excited state, double-beta decay: (2neutrino), Beta (velocity), Sensitivity (control systems), bayesian analysis, Nuclear Experiment (nucl-ex), Particle Physics, 010306 general physics, Engineering (miscellaneous), Nuclear Experiment, lepton number: violation, excited states, Physics, 010308 nuclear & particles physics, Majorana Neutrino, Gamma ray, sensitivity, Lepton number, gamma ray: emission, Excited state, Double beta decay, excited states, bayesian analysis, CUORE, Neutrinoless Double Beta Decay, Particle Physics, Neutrino, Majorana Neutrino, Dirac Neutrino
Abstract

The CUORE experiment is a large bolometric array searching for the lepton number violating neutrino-less double beta decay ($0\nu\beta\beta$) in the isotope $\mathrm{^{130}Te}$. In this work we present the latest results on two searches for the double beta decay (DBD) of $\mathrm{^{130}Te}$ to the first $0^{+}_2$ excited state of $\mathrm{^{130}Xe}$: the $0\nu\beta\beta$ decay and the Standard Model-allowed two-neutrinos double beta decay ($2\nu\beta\beta$). Both searches are based on a 372.5 kg$\times$yr TeO$_2$ exposure. The de-excitation gamma rays emitted by the excited Xe nucleus in the final state yield a unique signature, which can be searched for with low background by studying coincident events in two or more bolometers. The closely packed arrangement of the CUORE crystals constitutes a significant advantage in this regard. The median limit setting sensitivities at 90\% Credible Interval (C.I.) of the given searches were estimated as $\mathrm{S^{0\nu}_{1/2} = 5.6 \times 10^{24} \: \mathrm{yr}}$ for the ${0\nu\beta\beta}$ decay and $\mathrm{S^{2\nu}_{1/2} = 2.1 \times 10^{24} \: \mathrm{yr}}$ for the ${2\nu\beta\beta}$ decay. No significant evidence for either of the decay modes was observed and a Bayesian lower bound at $90\%$ C.I. on the decay half lives is obtained as: $\mathrm{(T_{1/2})^{0\nu}_{0^+_2} > 5.9 \times 10^{24} \: \mathrm{yr}}$ for the $0\nu\beta\beta$ mode and $\mathrm{(T_{1/2})^{2\nu}_{0^+_2} > 1.3 \times 10^{24} \: \mathrm{yr}}$ for the $2\nu\beta\beta$ mode. These represent the most stringent limits on the DBD of $^{130}$Te to excited states and improve by a factor $\sim5$ the previous results on this process., Comment: 13 pages, 6 figures

Published
2021

26. What changed in the Italian internal medicine and geriatric wards during the lockdown

Author

M. C. Nava, Ligia J. Dominguez, F. Giofre, S. Dassi, Stella Provini, Roberto Castello, Maria Elena Pipita, Raffaele Landolfi, I. Indiano, S. Schiavone, Renzo Rozzini, Matteo G. Della Porta, A. Cespiati, F. Perticone, G. Bartelloni, Miriam Gino, Maurizio Corsi, Lina Falanga, R. Di Quattro, G. Orio, Salvatore Piro, Antonio Mirijello, Alessio Molfino, L. Biondi, Leonardo A. Sechi, Luciano Ottonello, Marco Bertolotti, C. Sidoli, G. Colombo, C. Bussolino, A. Delitala, P. M. Mannucci, Luigina Guasti, Antonio Nouvenne, Marta Di Pasquale, P. Peasso, E. Favale, A. Volpini, Giulia Costanzo, C. Margaria, S. Morganti, Guido Moreo, F. Nasso, S. Dolenti, Enrico Strocchi, Laura Stefani, Cristian Petri, M. M. De Amicis, Maria Domenica Cappellini, E. Magnolfi, G. Principato, Fabio Fabbian, G. D'Aurizio, M. V. Libbra, Fabrizio Fabris, Michela Zanetti, P. Tarsitani, V. Piccinelli, R. Caruso, Andrea Artoni, G. Argiolas, A. D. Di Mauro, C. Custodero, Angela Sciacqua, Gabriella Gruden, Anna Ludovica Fracanzani, A. Falcetta, M. L. Matacena, E. Ianniello, G. Bogoni, M. Soldati, P. Agosti, Patrizia Mecocci, Benedetta Marigliano, Chiara Lonati, Luca Zanoli, Massimo Raspanti, F. Gandolfo, C. Catena, Paolo Rossi, Francesco Salerno, Carlotta Franchi, A. Gennaro, P. Bocchi, Elena Silvestri, R. Leonardi, Raffaella Rossio, M. Vanoli, V. Gioffre, L. Fondrieschi, B. D'Avanzo, N. Scaramellini, S. Del Giacco, A. da Porto, G. Serafini, I. Rossi, Giuseppe Palasciano, R. Gonella, Alice Valoriani, Antonella Afeltra, Filippo Alessandro Montalto, C. Antonucci, Giorgio Galanti, F. Montecucco, I. Aiello, Giuseppe Natoli, Antonio Brucato, C. Di Gennaro, Marco Zoli, Teresa Salvatore, Maria Ester Modeo, Mosè Bartone, Ilaria Ardoino, Flora Peyvandi, E. Simeone, Y. Grassi, Paolo Gallo, S. Leoni, S. Buffelli, Giacomo Emmi, Antonio Cittadini, Maria Teresa Guagnano, F. Corica, Giorgio Basile, G. Oberti, Giulia Grignani, G. Vannini, B. Graziella, A De Giorgi, Roberto Tarquini, G. M. De Vincenzo, M. Fogliati, G. Famularo, Antonio Picardi, Chiara Mussi, Andrea Maria Maresca, M. Pisati, Silvia Prolo, Domenico Girelli, Maurizio Muscaritoli, E. Amoruso, Silvia Ghidoni, Marco Vincenzo Lenti, Caterina Mengoli, Vanessa Bianconi, Carlo Vigorito, M. Galassi, A. Di Pino, M. Bellan, M. Girino, F. Bellone, V. Beccati, Luigi Anastasio, Laura Cortesi, M. Mattioli, Giuseppe Montalto, Gino Roberto Corazza, S. Fragapani, M. V. Rabuini, Pietro Minuz, Lara Caserza, R. Battaglia, F. Cacioppo, D. Cerminara, S. Di Marca, Gian Paolo Ceda, V. Beneduce, A. Ballestrero, Giuseppe Montrucchio, G. De Luca, G. P. Fra, Vincenzo Stanghellini, Raffaele Maio, A. Cavarape, N. Passariello, F. Berti, Patrizia Suppressa, Benedetta Stancanelli, A. Giorgi, Marta Rizzo, L. Colangelo, Massimo Montalto, A. Pilotto, Anna Licata, Francesco Violi, M. S. Pisciotta, Maria Perticone, Giuseppe Zuccalà, Virginia Boccardi, L. Ricevuti, Alessandra Marengoni, Giuseppe Romanelli, V. Saracco, Paola Riva, Giuseppe Paolisso, Alessandro Nobili, Francesco Saverio Vella, S. Tiraboschi, G. Pallini, G. Vischi, Nicola Lucio Liberato, R. Tiseo, Valter Monzani, Marcello Maggio, G. Damiani, G. Leoncini, M. Sanino, M. Cesari, Luana Castiglioni, G. Miglio, Luciano Rinaldi, M. Cilli, T. de Falco, C. Ricozzi, F. Tolloso, R. D. Diprizio, M. Berria, S. Mularo, A. Comitangelo, Carmelinda Ruggiero, Eugenio Ruggeri, Claudio Borghi, Tiziana Tognin, Antonino Catalano, A. Simili, Agostino Gaudio, Mario Barbagallo, Emanuela Miceli, Luca Pasina, A. Vignali, Alessandro Salvi, Giuseppe Delitala, Elena Succurro, Maria Antonietta Bleve, Alessio Novella, Sergio Harari, D. Sola, A. Dal Col, A. Di Sabatino, F. Ferrando, Enrico Petrillo, Francesco Baffa Bellucci, Andrea Ticinesi, L. La Malfa, Davide Firinu, Franco Arturi, Umberto Vespasiani Gentilucci, Lorenzo Malatino, Alessandra Bettiol, Valeria Savojardo, Francesca Mete, R. Quadri, Mancuso G, G. Pina, C. Poletto, G. Colussi, Sarah Damanti, Ginevra De Marchi, Graziana Lupattelli, Mario Pirisi, Pietro Castellino, A. Greco, Marta Clerici, Michela Novelli, Giulia Lancellotti, R. Volpi, R. Scurti, T. Prandini, Marco Carbone, E.A. Pulixi, Gianni Biolo, S. del Vecchio, W. Capeci, Tiziana Meschi, Luigi Fenoglio, Giovanna Fabio, R. Ghio, Francesco Cipollone, Leonardo Campiotti, G. P. Martino, Michela Pasino, Maria Grazia Serra, A. Bragagni, Roberto Pontremoli, Salvatore Corrao, Mauro Tettamanti, C. Catalano, L. Monaco, S. Berra, Alice Grossi, Giuseppe Bellelli, G. N. Imperiale, C. Principato, Gabriele Mascherini, E. Larovere, A. Pietrangelo, Giancarlo Labbadia, Fabiana Busti, I. Bertozzi, F. Napoli, Domenico Prisco, G. Nobili, Carlo Sabbà, Francesco Purrello, P. Pettinari, B. Tassone, G. Ceriani, G. Scanzi, S. Baldassarre, I. Mattioli, G. Sigon, Costanza Caccia Dominioni, Alessandro Squizzato, C. Gracin, Benedetta Boari, Roberto Manfredini, M. Grossi, Salvatore Minisola, Daniela Calipari, R. Alcidi, D. Lucente, V. Terranova, D'Avanzo B., Nobili A., Tettamanti M., Pasina L., Mannucci P.M., Pietrangelo A., Perticone F., Violi F., Corazza G.R., Corrao S., Marengoni A., Salerno F., Cesari M., Franchi C., Cortesi L., Miglio G., Ardoino I., Novella A., Prisco D., Silvestri E., Emmi G., Bettiol A., Mattioli I., Biolo G., Zanetti M., Bartelloni G., Vanoli M., Grignani G., Pulixi E.A., Lupattelli G., Bianconi V., Alcidi R., Girelli D., Busti F., Marchi G., Barbagallo M., Dominguez L., Beneduce V., Cacioppo F., Natoli G., Mularo S., Raspanti M., Zoli M., Matacena M.L., Orio G., Magnolfi E., Serafini G., Simili A., Palasciano G., Modeo M.E., Di Gennaro C., Cappellini M.D., Fabio G., de Amicis M.M., de Luca G., Scaramellini N., Rossi P.D., Damanti S., Clerici M., Leoni S., Di Mauro A.D., Di Sabatino A., Miceli E., Lenti M.V., Pisati M., Dominioni C.C., Pontremoli R., Beccati V., Nobili G., Leoncini G., Anastasio L., Carbone M., Cipollone F., Guagnano M.T., Rossi I., Mancuso G., Calipari D., Bartone M., Delitala G., Berria M., Delitala A., Muscaritoli M., Molfino A., Petrillo E., Giorgi A., Gracin C., Zuccala G., D'Aurizio G., Romanelli G., Volpini A., Lucente D., Picardi A., Gentilucci U.V., Gallo P., Bellelli G., Corsi M., Antonucci C., Sidoli C., Principato G., Arturi F., Succurro E., Tassone B., Giofre F., Serra M.G., Bleve M.A., Brucato A., de Falco T., Fabris F., Bertozzi I., Bogoni G., Rabuini M.V., Prandini T., Manfredini R., Fabbian F., Boari B., de Giorgi A., Tiseo R., Paolisso G., Rizzo M.R., Catalano C., Borghi C., Strocchi E., Ianniello E., Soldati M., Schiavone S., Bragagni A., Sabba C., Vella F.S., Suppressa P., de Vincenzo G.M., Comitangelo A., Amoruso E., Custodero C., Fenoglio L., Falcetta A., Fracanzani A.L., Tiraboschi S., Cespiati A., Oberti G., Sigon G., Peyvandi F., Rossio R., Colombo G., Agosti P., Monzani V., Savojardo V., Ceriani G., Pallini G., Montecucco F., Ottonello L., Caserza L., Vischi G., Liberato N.L., Tognin T., Purrello F., Di Pino A., Piro S., Rozzini R., Falanga L., Pisciotta M.S., Bellucci F.B., Buffelli S., Montrucchio G., Peasso P., Favale E., Poletto C., Margaria C., Sanino M., Guasti L., Castiglioni L., Maresca A., Squizzato A., Campiotti L., Grossi A., Diprizio R.D., Bertolotti M., Mussi C., Lancellotti G., Libbra M.V., Galassi M., Grassi Y., Greco A., Sciacqua A., Perticone M., Battaglia R., Maio R., Stanghellini V., Ruggeri E., del Vecchio S., Salvi A., Leonardi R., Damiani G., Capeci W., Mattioli M., Martino G.P., Biondi L., Pettinari P., Ghio R., Dal Col A., Minisola S., Colangelo L., Cilli M., Labbadia G., Afeltra A., Marigliano B., Pipita M.E., Castellino P., Zanoli L., Gennaro A., Gaudio A., Saracco V., Fogliati M., Bussolino C., Mete F., Gino M., Vigorito C., Cittadini A., Moreo G., Prolo S., Pina G., Ballestrero A., Ferrando F., Gonella R., Cerminara D., Berra S., Dassi S., Nava M.C., Graziella B., Baldassarre S., Fragapani S., Gruden G., Galanti G., Mascherini G., Petri C., Stefani L., Girino M., Piccinelli V., Nasso F., Gioffre V., Pasquale M., Sechi L., Catena C., Colussi G., Cavarape A., da Porto A., Passariello N., Rinaldi L., Berti F., Famularo G., Tarsitani P., Castello R., Pasino M., Ceda G.P., Maggio M.G., Morganti S., Artoni A., Grossi M., Del Giacco S., Firinu D., Costanzo G., Argiolas G., Montalto G., Licata A., Montalto F.A., Corica F., Basile G., Catalano A., Bellone F., Principato C., Malatino L., Stancanelli B., Terranova V., Di Marca S., Di Quattro R., la Malfa L., Caruso R., Mecocci P., Ruggiero C., Boccardi V., Meschi T., Ticinesi A., Nouvenne A., Minuz P., Fondrieschi L., Imperiale G.N., Pirisi M., Fra G.P., Sola D., Bellan M., Porta M., Riva P., Quadri R., Larovere E., Novelli M., Scanzi G., Mengoli C., Provini S., Ricevuti L., Simeone E., Scurti R., Tolloso F., Tarquini R., Valoriani A., Dolenti S., Vannini G., Volpi R., Bocchi P., Vignali A., Harari S., Lonati C., Napoli F., Aiello I., Landolfi R., Montalto M., Mirijello A., Ghidoni S., Salvatore T., Monaco L., Ricozzi C., Pilotto A., Indiano I., Gandolfo F., D'Avanzo, B, Nobili, A, Tettamanti, M, Pasina, L, Mannucci, P, Bellelli, G, D'Avanzo, B., Nobili, A., Tettamanti, M., Pasina, L., Mannucci, P. M., Pietrangelo, A., Perticone, F., Violi, F., Corazza, G. R., Corrao, S., Marengoni, A., Salerno, F., Cesari, M., Franchi, C., Cortesi, L., Miglio, G., Ardoino, I., Novella, A., Prisco, D., Silvestri, E., Emmi, G., Bettiol, A., Mattioli, I., Biolo, G., Zanetti, M., Bartelloni, G., Vanoli, M., Grignani, G., Pulixi, E. A., Lupattelli, G., Bianconi, V., Alcidi, R., Girelli, D., Busti, F., Marchi, G., Barbagallo, M., Dominguez, L., Beneduce, V., Cacioppo, F., Natoli, G., Mularo, S., Raspanti, M., Zoli, M., Matacena, M. L., Orio, G., Magnolfi, E., Serafini, G., Simili, A., Palasciano, G., Modeo, M. E., Di Gennaro, C., Cappellini, M. D., Fabio, G., de Amicis, M. M., de Luca, G., Scaramellini, N., Rossi, P. D., Damanti, S., Clerici, M., Leoni, S., Di Mauro, A. D., Di Sabatino, A., Miceli, E., Lenti, M. V., Pisati, M., Dominioni, C. C., Pontremoli, R., Beccati, V., Nobili, G., Leoncini, G., Anastasio, L., Carbone, M., Cipollone, F., Guagnano, M. T., Rossi, I., Mancuso, G., Calipari, D., Bartone, M., Delitala, G., Berria, M., Delitala, A., Muscaritoli, M., Molfino, A., Petrillo, E., Giorgi, A., Gracin, C., Zuccala, G., D'Aurizio, G., Romanelli, G., Volpini, A., Lucente, D., Picardi, A., Gentilucci, U. V., Gallo, P., Bellelli, G., Corsi, M., Antonucci, C., Sidoli, C., Principato, G., Arturi, F., Succurro, E., Tassone, B., Giofre, F., Serra, M. G., Bleve, M. A., Brucato, A., de Falco, T., Fabris, F., Bertozzi, I., Bogoni, G., Rabuini, M. V., Prandini, T., Manfredini, R., Fabbian, F., Boari, B., de Giorgi, A., Tiseo, R., Paolisso, G., Rizzo, M. R., Catalano, C., Borghi, C., Strocchi, E., Ianniello, E., Soldati, M., Schiavone, S., Bragagni, A., Sabba, C., Vella, F. S., Suppressa, P., de Vincenzo, G. M., Comitangelo, A., Amoruso, E., Custodero, C., Fenoglio, L., Falcetta, A., Fracanzani, A. L., Tiraboschi, S., Cespiati, A., Oberti, G., Sigon, G., Peyvandi, F., Rossio, R., Colombo, G., Agosti, P., Monzani, V., Savojardo, V., Ceriani, G., Pallini, G., Montecucco, F., Ottonello, L., Caserza, L., Vischi, G., Liberato, N. L., Tognin, T., Purrello, F., Di Pino, A., Piro, S., Rozzini, R., Falanga, L., Pisciotta, M. S., Bellucci, F. B., Buffelli, S., Montrucchio, G., Peasso, P., Favale, E., Poletto, C., Margaria, C., Sanino, M., Guasti, L., Castiglioni, L., Maresca, A., Squizzato, A., Campiotti, L., Grossi, A., Diprizio, R. D., Bertolotti, M., Mussi, C., Lancellotti, G., Libbra, M. V., Galassi, M., Grassi, Y., Greco, A., Sciacqua, A., Perticone, M., Battaglia, R., Maio, R., Stanghellini, V., Ruggeri, E., del Vecchio, S., Salvi, A., Leonardi, R., Damiani, G., Capeci, W., Mattioli, M., Martino, G. P., Biondi, L., Pettinari, P., Ghio, R., Dal Col, A., Minisola, S., Colangelo, L., Cilli, M., Labbadia, G., Afeltra, A., Marigliano, B., Pipita, M. E., Castellino, P., Zanoli, L., Gennaro, A., Gaudio, A., Saracco, V., Fogliati, M., Bussolino, C., Mete, F., Gino, M., Vigorito, C., Cittadini, A., Moreo, G., Prolo, S., Pina, G., Ballestrero, A., Ferrando, F., Gonella, R., Cerminara, D., Berra, S., Dassi, S., Nava, M. C., Graziella, B., Baldassarre, S., Fragapani, S., Gruden, G., Galanti, G., Mascherini, G., Petri, C., Stefani, L., Girino, M., Piccinelli, V., Nasso, F., Gioffre, V., Pasquale, M., Sechi, L., Catena, C., Colussi, G., Cavarape, A., da Porto, A., Passariello, N., Rinaldi, L., Berti, F., Famularo, G., Tarsitani, P., Castello, R., Pasino, M., Ceda, G. P., Maggio, M. G., Morganti, S., Artoni, A., Grossi, M., Del Giacco, S., Firinu, D., Costanzo, G., Argiolas, G., Montalto, G., Licata, A., Montalto, F. A., Corica, F., Basile, G., Catalano, A., Bellone, F., Principato, C., Malatino, L., Stancanelli, B., Terranova, V., Di Marca, S., Di Quattro, R., la Malfa, L., Caruso, R., Mecocci, P., Ruggiero, C., Boccardi, V., Meschi, T., Ticinesi, A., Nouvenne, A., Minuz, P., Fondrieschi, L., Imperiale, G. N., Pirisi, M., Fra, G. P., Sola, D., Bellan, M., Porta, M., Riva, P., Quadri, R., Larovere, E., Novelli, M., Scanzi, G., Mengoli, C., Provini, S., Ricevuti, L., Simeone, E., Scurti, R., Tolloso, F., Tarquini, R., Valoriani, A., Dolenti, S., Vannini, G., Volpi, R., Bocchi, P., Vignali, A., Harari, S., Lonati, C., Napoli, F., Aiello, I., Landolfi, R., Montalto, M., Mirijello, A., Ghidoni, S., Salvatore, T., Monaco, L., Ricozzi, C., Pilotto, A., Indiano, I., and Gandolfo, F.

Subjects
2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Aged, Humans, Italy, Hospitals, Internal Medicine, MEDLINE, geriatric, Socio-culturale, law.invention, lockdown, Hospital, Patient Transport, law, Pandemic, Hospital discharge, medicine, Aged, Hospitals, Humans, Internal Medicine, Italy, Letter to the Editor, Internal medicine, LS7_9, business.industry, geriatric patients, medicine.disease, Intensive care unit, Internal medicine, geriatric patients, lockdown, covid-19, covid-19, Medical emergency, business, Human
Abstract

A total of 48 internal medicine or geriatric wards among the 93 adhering to the register REPOSI answered an online questionnaire aimed to investigate the characteristics and activities of converted and non-converted wards in the crucial period of the first wave of the epidemic, 22 February-4 May 2020

Published
2021

28. Improved Limit on Neutrinoless Double-Beta Decay in Te130 with CUORE

Author

Yudi Ma, Massimiliano Clemenza, C. Pagliarone, Carlo Cosmelli, B. S. Wang, Silvia Capelli, Massimiliano Nastasi, S. Pirro, N. Chott, C. Brofferio, C. Rosenfeld, V. Novati, Davide Chiesa, A. Caminata, L. Ma, V. Dompè, Ezio Previtali, Marco Pallavicini, A. D'Addabbo, P. Gorla, F. Ferroni, C. Tomei, James R. Wilson, B. Welliver, K. Wilson, Emanuele Ferri, Carlo Ligi, A. Campani, R. G. Huang, I. Nutini, D. Q. Adams, I. Dafinei, M. Sakai, Jonathan Ouellet, G. Bari, K. Alfonso, Giovanni Benato, N. D. Scielzo, C. Nones, E. Fiorini, C. Bucci, Lucia Canonica, S. Di Domizio, A. Puiu, T. D. Gutierrez, C. Rusconi, M. Faverzani, Deqing Fang, C. J. Davis, Laura Cardani, B. K. Fujikawa, L. Zanotti, F. Bellini, S. Morganti, Stefano Dell'Oro, A. Branca, L. Marini, M. Vignati, S. L. Wagaarachchi, S. Pozzi, J. Johnston, L. Pattavina, A. Giachero, V. Sharma, R. J. Creswick, L. Cappelli, B. Schmidt, T. Napolitano, G. Pessina, N. Moggi, A. Giuliani, Stefano Zucchelli, O. Azzolini, M. Biassoni, V. Pettinacci, Samuele Sangiorgio, A. Nucciotti, M. Sisti, S. Copello, C. Alduino, G. Fantini, S. Zimmermann, D. D'Aguanno, L. Pagnanini, L. Gironi, F. T. Avignone, Paolo Carniti, M. A. Franceschi, Eric B. Norman, M. Pavan, J. Nikkel, P. T. Surukuchi, Lindley Winslow, T. O'Donnell, F. Terranova, H. Z. Huang, Y. Mei, Xiangyu Cao, G. Keppel, Oliviero Cremonesi, K. M. Heeger, Ke Han, Reina H. Maruyama, Stuart J. Freedman, N. Casali, Yu. G. Kolomensky, Claudio Gotti, C. Pira, L. Taffarello, Virendra Singh, and Danielle Speller

Subjects
Physics, Semileptonic decay, Particle physics, General Physics and Astronomy, 01 natural sciences, Lower limit, MAJORANA, CUORE, Double beta decay, 0103 physical sciences, Limit (mathematics), Sensitivity (control systems), Neutrino, 010306 general physics
Abstract

We report new results from the search for neutrinoless double-beta decay in ^{130} Te with the CUORE detector. This search benefits from a fourfold increase in exposure, lower trigger thresholds, and analysis improvements relative to our previous results. We observe a background of (1.38±0.07)×10^{-2} counts/(keV kg yr)) in the 0νββ decay region of interest and, with a total exposure of 372.5 kg yr, we attain a median exclusion sensitivity of 1.7×10^{25} yr. We find no evidence for 0νββ decay and set a 90% credibility interval Bayesian lower limit of 3.2×10^{25} yr on the ^{130} Te half-life for this process. In the hypothesis that 0νββ decay is mediated by light Majorana neutrinos, this results in an upper limit on the effective Majorana mass of 75-350 meV, depending on the nuclear matrix elements used.

Published
2020

29. Treatment of Delirium in Older Persons: What We Should Not Do!

Author

Giovanna Pelà, Sara Tagliaferri, Giuseppe Bellelli, Marcello Maggio, Fulvio Lauretani, S. Morganti, Lauretani, F, Bellelli, G, Pela, G, Morganti, S, Tagliaferri, S, and Maggio, M

Subjects
medicine.medical_specialty, media_common.quotation_subject, Review, Catalysis, Pharmacological treatment, Inorganic Chemistry, lcsh:Chemistry, 03 medical and health sciences, 0302 clinical medicine, delirium, pharmacological treatment, Orientation (mental), Perception, Cerebral function, Medicine, Humans, Cognitive Dysfunction, 030212 general & internal medicine, Physical and Theoretical Chemistry, Intensive care medicine, Molecular Biology, lcsh:QH301-705.5, Spectroscopy, Brain function, media_common, Balance (ability), older person, Psychotropic Drugs, business.industry, Organic Chemistry, Stressor, General Medicine, Computer Science Applications, Hospitalization, neurogeriatric disorders, lcsh:Biology (General), lcsh:QD1-999, Acute Disease, older persons, Delirium, neurogeriatric disorder, medicine.symptom, business, Cognition Disorders, 030217 neurology & neurosurgery
Abstract

The presentation of common acute diseases in older age is often referred to as “atypical”. Frequently, the symptoms are neither single nor tissue related. In most cases, the onset of symptoms and diseases is the expression of a diminished reserve with a failure of the body system and imbalance of brain function. Delirium is one of the main devastating and prevalent atypical symptoms and could be considered as a geriatric syndrome. It encompasses an array of neuropsychiatric symptoms and represents a disarrangement of the cerebral function in response to one or more stressors. The most recent definition, reported in the DSM-V, depicts delirium as a clear disturbance in attention and awareness. The deficit is to be developed in a relatively short time period (usually hours or days). The attention disorder must be associated with another cognitive impairment in memory, orientation, language, visual-spatial or perception abilities. For the treatment, it is imperative to remove the potential causes of delirium before prescribing drugs. Even a non-pharmacological approach to reducing the precipitating causes should be identified and planned. When we are forced to approach the pharmacological treatment of hyperactive delirium in older persons, we should select highly cost-effective drugs. High attention should be devoted to the correct balance between improvement of psychiatric symptoms and occurrence of side effects. Clinicians should be guided in the correct choice of drugs following cluster symptoms presentation, excluding drugs that could potentially produce complications rather than advantages. In this brief point-of-view, we propose a novel pharmacological flow-chart of treatment in relation to the basic clusters of diseases of an older patient acutely admitted to the hospital and, in particular, we emphasize “What We Should Not Do!”, with the intention of avoiding possible side effects of drugs used.

Published
2020

30. Perspectives of lowering CUORE thresholds with Optimum Trigger

Author

Monica Sisti, A. Bersani, C. Brofferio, G. Fantini, A. Caminata, Marco Pallavicini, B. Welliver, C. Pagliarone, R. G. Huang, M. Faverzani, Y. u. G. Kolomensky, H. Z. Huang, G. Keppel, Massimiliano Nastasi, Yudi Ma, S. Pozzi, S. L. Wagaarachchi, C. Cosmelli, A. Giuliani, C. Pira, C. Rusconi, Ke Han, A. Branca, N. D. Scielzo, Reina H. Maruyama, N. Casali, Stefano Dell'Oro, Lucia Canonica, F. Bellini, I. Dafinei, V. Novati, T. Wise, V. Pettinacci, Davide Chiesa, Stefano Zucchelli, Laura Cardani, L. Gironi, M. Pavan, B. K. Fujikawa, Y. Mei, V. Singh, D. D'Aguanno, F. T. Avignone, L. Taffarello, R. J. Creswick, C. Rosenfeld, P. Gorla, Danielle Speller, F. Ferroni, C. Tomei, M. Vignati, E. Previtali, Simone Capelli, D. Q. Adams, L. Marini, C. J. Davis, K. Alfonso, T. O'Donnell, B. Schmidt, N. Chott, C. Nones, A. Puiu, Lindley Winslow, S. Zimmermann, Oliviero Cremonesi, J. Johnston, L. Pattavina, Irene Nutini, S. Copello, C. Bucci, Miriam Lucio Martinez, Paolo Carniti, Sergio Di Domizio, S. Pirro, Xi-Guang Cao, E. Fiorini, S. J. Freedman, K. M. Heeger, Luigi Cappelli, T. D. Gutierrez, F. Terranova, K. Wilson, G. Pessina, B. S. Wang, Jonathan Ouellet, G. Bari, O. Azzolini, Evelyn Ferri, N. Moggi, Samuele Sangiorgio, A. Nucciotti, C. Alduino, Jeremy S. Cushman, S. Morganti, L. Zanotti, Carlo Ligi, A. Campani, V. Dompè, A. D'Addabbo, A. Leder, J. S. Wilson, Franceschi, Eric B. Norman, M. Sakai, T. Napolitano, M. Biassoni, Giovanni Benato, A. Drobizhev, C. Gotti, A. Giachero, D. Q. Fang, Massimiliano Clemenza, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay

Subjects
Physics, History, CUORE, 010308 nuclear & particles physics, Physics::Instrumentation and Detectors, WIMP nucleus: scattering, trigger: programming, 01 natural sciences, Large target, tellurium: oxygen, Computer Science Applications, Education, Combinatorics, energy: threshold, Low energy, double-beta decay: (0neutrino), 0103 physical sciences, High Energy Physics::Experiment, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, activity report, energy: low
Abstract

Author(s): Dompe, V; Adams, DQ; Alduino, C; Alfonso, K; Avignone, FT; Azzolini, O; Bari, G; Bellini, F; Benato, G; Bersani, A; Biassoni, M; Branca, A; Brofferio, C; Bucci, C; Caminata, A; Campani, A; Canonica, L; Cao, XG; Capelli, S; Cappelli, L; Cardani, L; Carniti, P; Casali, N; Chiesa, D; Chott, N; Clemenza, M; Copello, S; Cosmelli, C; Cremonesi, O; Creswick, RJ; Cushman, JS; D'Addabbo, A; D'Aguanno, D; Dafinei, I; Davis, CJ; Dell'Oro, S; Domizio, SD; Drobizhev, A; Fang, DQ; Fantini, G; Faverzani, M; Ferri, E; Ferroni, F; Fiorini, E; Franceschi, MA; Freedman, SJ; Fujikawa, BK; Giachero, A; Gironi, L; Giuliani, A; Gorla, P; Gotti, C; Gutierrez, TD; Han, K; Heeger, KM; Huang, RG; Huang, HZ; Johnston, J; Keppel, G; Kolomensky, YG; Leder, A; Ligi, C; Ma, YG; Marini, L; Martinez, M; Maruyama, RH; Mei, Y; Moggi, N; Morganti, S; Napolitano, T; Nastasi, M; Nones, C; Norman, EB; Novati, V; Nucciotti, A; Nutini, I; O'Donnell, T; Ouellet, JL; Pagliarone, CE; Pallavicini, M; Pattavina, L; Pavan, M; Pessina, G; Pettinacci, V; Pira, C | Abstract: CUORE is a cryogenic experiment that focuses on the search of neutrinoless double beta decay in 130Te and it is located at the Gran Sasso National Laboratories. Its detector consists of 988 TeO2 crystals operating at a base temperature of ∼10 mK. It is the first ton-scale bolometric experiment ever realized for this purpose. Thanks to its large target mass and ultra-low background, the CUORE detector is also suitable for the search of other rare phenomena. In particular the low energy part of the spectra is interesting for the detection of WIMP-nuclei scattering reactions. One of the most important requirements to perform these studies is represented by the achievement of a stable energy threshold lower than 10 keV. Here, the CUORE capability to accomplish this purpose using a low energy software trigger will be presented and described.

Published
2020

31. Measurements of the Absolute Branching Fractions of B± →k±Xc c

Author

A. J. Edwards, F. Simonetto, W. F. Mader, R. H. Schindler, Fry, Shanhui Fan, I Eschrich, W. Menges, M Bruinsma, K. Suzuki, T Schalk, R. Kroeger, J. M. Bauer, D. Boutigny, H. Nicholson, A Petzold, Marcello Rotondo, AT Watson, Martino Margoni, H. U. Flaecher, L. M. Cremaldi, M. Verderi, A Pompili, T. Hadig, U. Mallik, S. K. Swain, KS Chaisanguanthum, Muller, J. F. Strube, Roberto Calabrese, AN Yushkov, E. Gabathuler, Jordan Nash, O. Hamon, R. R. Kofler, M. Krishnamurthy, C. M. Cormack, AE Blinov, WH Toki, R Schwierz, Heiko Lacker, M Battaglia, D. G. Hitlin, S. Ye, M Andreotti, T. C. Petersen, Corrado Angelini, W. Gradl, Stephen Sekula, G Mancinelli, F. C. Porter, R. Ter-Antonyan, R. C. Field, D. E. Wagoner, W. O. Ruddick, Gabriele Simi, A. Buzzo, A. K. Mohapatra, D. J. Payne, J Kadyk, L Piemontese, F. Bucci, P. Wang, ML Vetere, G Lynch, D. Côté, L. Gioi, TW Beck, P. S. Jackson, R. Godang, D. Piccolo, Tisserand, G. Therin, J Marks, W. Bhimji, Gill, Q Zeng, S. Rodier, Nicola Neri, F. Lodovico, O. L. Buchmueller, D. Su, Nicolo De Groot, Wp Vazquez, B. Cheng, Chunhui Chen, K. R. Schubert, C. L. Davis, R. Gamet, H. L. Lynch, A. Gaidot, G. P. Gopal, B. Viaud, Maurizio Pierini, M. P. Kelly, M Saleem, D. J. Bard, A. Calcaterra, J. Ocariz, R Nogowski, M. Piccolo, M. T. Allen, S. Saremi, M Mandelkern, A. W. Weidemann, Matteo Rama, D. M. Strom, Mauro Morandin, G Brandenburg, S. Playfer, C. Bozzi, M. Haire, J. C. Williams, Halyo, K. Honscheid, C. A. Chavez, C. L. Edgar, J Zhang, LT Kerth, D. Dong, DC Williams, JE Sundermann, SE Morgan, J. M. Roney, JS Minamora, Luca Lista, S. J. Gowdy, K. A. George, J. G. Smith, M. B. Nikolich, D Kirkby, C. Cartaro, A. Oyanguren, G. Batignani, R. Sacco, C. Roat, M. Benayoun, Fabio Cossutti, M. A. Mazzoni, G. Wormser, RJ Wilson, H. L. Snoek, S Curry, J. W. Gary, K. Goetzen, B. Franek, P Bloom, R. Frey, H. J. Bulten, CJ Flacco, A. M. Eisner, D. W. G. S. Leith, Nicolas Berger, D. A. Hopkins, S. M. Spanier, Vladimir Blinov, G Vasileiadis, B Lewandowski, J Kroseberg, C. Gatto, A Santroni, S Tosi, C. K. Lae, D. B. MacFarlane, R. J. Barlow, G. Rizzo, E. P. Solodov, D Altenburg, W. N. Cottingham, N. Chevalier, M. Posocco, Marco Bomben, R. Barate, D. Bernard, JD Richman, C Thiebaux, J.J. Reidy, R. Bula, T. Cuhadar-Donszelmann, T. Schroeder, Johnson, G. Schott, M. H. Kelsey, T. Abe, J. Stelzer, C. Touramanis, J. P. Burke, E. Torrence, Giuseppe Della Ricca, Sw. Banerjee, M Pappagallo, Abner Soffer, C. Hearty, R. Claus, S. Prell, Matteo Negrini, Thomas Allmendinger, C. Dallapiccola, J. J. Hollar, Y. P. Lau, D. Fortin, J. A. McKenna, Kyung-Soo Yi, G. Calderini, Douglas Wright, P Lund, James H Cochran, R. Cenci, T. Glanzman, R. L. Flack, HP Paar, J. L. Ritchie, EA Eckhart, S. Bettarini, A. J.S. Smith, Philippe Grenier, M Macri, J. M. LoSecco, E Feltresi, A. Zallo, J. Libby, AB Breon, FS Tehrani, G. Grosdidier, I. J. Forster, D. J. Summers, M. Spitznagel, B Stugu, S. F. Ganzhur, H. R. Band, B Spaan, H. B. Crawley, I. Kitayama, S. I. Serednyakov, MG Wilson, M Morii, KE Ford, D Best, Yuri Skovpen, R. J. Sobie, G. W. London, Y Groysman, J. C. Dingfelder, N. B. Sinev, BL Hartfiel, R. Liu, Daniele Del Re, Luth, A. Perazzo, C. Voena, L. Vitale, W. R. Innes, RG Jacobsen, E Chen, Alam, T. S. Mattison, D. A. Sanders, F. Martinez-Vidal, J. Chauveau, M. J.J. John, R. Aleksan, S. B. Zain, G. P. Dubois-Felsmann, H. A. Neal, S. Willocq, D. Monorchio, I Ofte, K Peters, T. B. Moore, Q. K. Wong, B. T. Meadows, J. Biesiada, A Samuel, V. B. Koptchev, V. E. Ozcan, S. A. Majewski, A Seiden, P. Tan, C. Hast, D. J. Lange, G. Piredda, A. Dvoretskii, W. Kozanecki, M. Legendre, GS Abrams, G. Raven, T. Held, C. Lu, D. Judd, Y. B. Pan, D. Bettoni, M. Lu, Dmytro Kovalskyi, J. I. Yi, C. M. Brown, Y Xie, H. W. Zhao, P. D. Dauncey, J. P. Lees, R. Kowalewski, A. Hocker, S. Ahmed, D. Gamba, A. Lusiani, F. Gallo, RK Mommsen, P. R. Burchat, S Schrenk, M. Pioppi, F. Polci, N. S. Knecht, V. P. Druzhinin, Y Karyotakis, W. J. Wisniewski, A. Stocchi, F. R. Wappler, CM Hawkes, F. Forti, P. C. Kim, A. Lazzaro, J. E. Brau, Tim Adye, X. Giroux, M. Carpinelli, M. T. Naisbit, Lydia Roos, M. Morganti, C. Voci, Eleonora Luppi, R. Baldini-Ferroli, J. Schwiening, Julie Malcles, R. D. Kass, Q. H. Guo, C. De La Vaissiere, H. Kagan, H. Schröder, R. J. Parry, D. Dujmic, Tetiana Hrynova, K. K. Gan, D. A. Roberts, Anders Ryd, N. D. Qi, J. M. Thompson, C. Yeche, A. D'Orazio, F. E. Taylor, A Chen, T. M. Hong, MA Mazur, BA Schumm, D. Aston, C Campagnari, GH de Monchenault, M. H. Schune, Guglielmo De Nardo, G. Marchiori, U. Uwer, BC Shen, J Wu, M. Zito, NA Roe, C. P. O'Grady, M Dickopp, W. Dunwoodie, PJ Clark, M. A. Baak, M Chao, A. V. Telnov, WT Ford, J. Olsen, E. O. Olaiya, M. A. Saeed, W. T. Meyer, Y. S. Zhu, A. Mihalyi, Eyges, R. Stroili, J Schubert, Wagner, Hyunyong Kim, Maurizio Biasini, N. R. Barlow, Pierluigi Paolucci, U Nauenberg, Kenji Hamano, T.R. McMahon, C Buchanan, TJ Harrison, Ulrik Egede, Matthew J. Graham, M. Fritsch, T Piatenko, F Couderc, RW Kadel, S. S. Hertzbach, N. Danielson, R. Messner, A Zghiche, R. Faccini, Sokoloff, F. Ferrarotto, A. J. Lankford, Marcella Bona, AD Bukin, C. Patrignani, A. Cunha, F. Palombo, D Brown, E. Paoloni, F. Salvatore, JF Hirschauer, EJ Hill, S. Pacetti, Owen Rosser Long, G. B. Mohanty, L. Wilden, A. Kreisel, Kefeng Wang, F. Galeazzi, R. Cowan, Gabriele Benelli, P. Taras, Lepeltier, R. F. Schwitters, Mohamed H. Ahmed, M. L. Kocian, P. Roudeau, P. D. Jackson, AJ Hart, A. P. Onuchin, R. K. Yamamoto, J. J. Back, G. Finocchiaro, L Zhang, H. Staengle, PJ Oddone, W Verkerke, J Brose, LM Mir, E. Grauges, X. R. Chen, S. Brunet, M. G. Green, Adrian John Bevan, R. Bartoldus, P Kyberd, Zongfu Yu, G. A. Cowan, M. Gaspero, J. P. Coleman, G. Eigen, M Bondioli, C. T. Potter, A. Snyder, Mario Giorgi, Monge, Michael Steinke, S. Morganti, L. Gladney, M. J. Charles, R. Eckmann, F. F. Wilson, L. Bosisio, S Otto, Sridhara Dasu, M. Davier, G Kukartsev, W Roethel, Karsten Koeneke, K. A. Ulmer, Francesco Fabozzi, G. R. Bonneaud, A. J.R. Weinstein, Colin Jessop, Mousumi Datta, R. Prepost, Andrei Gritsan, I Narsky, SD Foulkes, HK Hadavand, Azzolini, A. Khan, F. Bellini, T. Orimoto, M Barrett, A. Olivas, M. Weaver, G. Vasseur, K. T. Flood, M. L. Perl, J. T. Boyd, Joseph Izen, K. C. Schofield, A. Roodman, R Andreassen, T. Pulliam, S Rahatlou, J. A. Ernst, H. Briand, Roland Waldi, F. Ferroni, N. Cavallo, L. Lanceri, Stéphane Plaszczynski, D. A. Bowerman, Paul Fraser Harrison, P. M. Patel, S. J. Chen, J.H. Panetta, X. Chai, M. K. Sullivan, A. Jawahery, Y. G. Kolomensky, Gabriella Sciolla, W. M. Bugg, G. Cibinetto, B. N. Ratcliff, Emanuele Di Marco, RN Cahn, P Spradlin, Eschenburg, B. A. Petersen, J. Dorfan, A. M. Boyarski, C. L. Brown, JW Berryhill, MT Ronan, P. E. Kutter, P. K. Behera, Ph Leruste, F Muheim, G.J. Wagner, N. Arnaud, B. Mayer, A. K. Yarritu, Convery, I. M. Peruzzi, C. H. Cheng, Luigi Del Buono, B. Aubert, E Robutti, H. Marsiske, R. de Sangro, S. L. Wu, RS Dubitzky, F. Bianchi, A. E. Rubin, N. van Bakel, C. C. Young, F. Diberder, J. Allison, WA Wenzel, A. M. Lutz, Poireau, Hui Li, G. Rong, Sergio Grancagnolo, R Contri, S. Passaggio, R. S. Panvini, M Pelizaeus, Wilson, W. D. Hulsbergen, Xingguo Li, M. V. Purohit, J. Albert, Bruce Mellado, Klose, M. Wittgen, E Charles, Pieter David, Ziegler, V. B. Golubev, Roberto Covarelli, A. Palano, G. Cavoto, David Hutchcroft, Bryan Dahmes, S. Luitz, S Schenk, J. Va’vra, Sharma, D. Hufnagel, Peter Elmer, DP Stoker, E Won, A. M. Eichenbaum, S. Ricciardi, L Teodorescu, C. A. Heusch, E. A. Kravchenko, Crisostomo Sciacca, CT Day, J. C. Chen, P. Patteri, R Capra, D. Wright, B. Bhuyan, B. G. Fulsom, X. C. Lou, J. J. Walsh, A. M. Rahimi, T. E. Latham, D. N. Brown, Gaillard, G. D. Lafferty, T Brandt, M Pripstein, Markus Cristinziani, O. Igonkina, F. X. Yumiceva, J Button-Shafer, S. H. Robertson, G Nesom, S. Emery, G. Blaylock, Herbert Koch, A Hauke, Lombardo, F. Blanc, A. Satpathy, M. C. Hodgkinson, G. Graziani, E. I. Rosenberg, W. S. Lockman, A. A. Salnikov, M. C. Simani, F. Anulli, S. Dittongo, U Langenegger, Lees J.P., Poireau V., Tisserand V., Grauges E., Palano A., Eigen G., Brown D.N., Kolomensky Y.G., Fritsch M., Koch H., Schroeder T., Cheaib R., Hearty C., Mattison T.S., McKenna J.A., So R.Y., Blinov V.E., Buzykaev A.R., Druzhinin V.P., Golubev V.B., Kozyrev E.A., Kravchenko E.A., Onuchin A.P., Serednyakov S.I., Skovpen Y.I., Solodov E.P., Todyshev K.Y., Lankford A.J., Dey B., Gary J.W., Long O., Eisner A.M., Lockman W.S., Panduro Vazquez W., Chao D.S., Cheng C.H., Echenard B., Flood K.T., Hitlin D.G., Kim J., Li Y., Miyashita T.S., Ongmongkolkul P., Porter F.C., Rohrken M., Huard Z., Meadows B.T., Pushpawela B.G., Sokoloff M.D., Sun L., Smith J.G., Wagner S.R., Bernard D., Verderi M., Bettoni D., Bozzi C., Calabrese R., Cibinetto G., Fioravanti E., Garzia I., Luppi E., Santoro V., Calcaterra A., De Sangro R., Finocchiaro G., Martellotti S., Patteri P., Peruzzi I.M., Piccolo M., Rotondo M., Zallo A., Passaggio S., Patrignani C., Shuve B.J., Lacker H.M., Bhuyan B., Mallik U., Chen C., Cochran J., Prell S., Gritsan A.V., Arnaud N., Davier M., Le Diberder F., Lutz A.M., Wormser G., Lange D.J., Wright D.M., Coleman J.P., Gabathuler E., Hutchcroft D.E., Payne D.J., Touramanis C., Bevan A.J., Di Lodovico F., Sacco R., Cowan G., Banerjee S., Davis C.L., Denig A.G., Gradl W., Griessinger K., Hafner A., Schubert K.R., Barlow R.J., Lafferty G.D., Cenci R., Jawahery A., Roberts D.A., Cowan R., Robertson S.H., Seddon R.M., Neri N., Palombo F., Cremaldi L., Godang R., Summers D.J., Taras P., De Nardo G., Sciacca C., Raven G., Jessop C.P., Losecco J.M., Honscheid K., Kass R., Gaz A., Margoni M., Posocco M., Simi G., Simonetto F., Stroili R., Akar S., Ben-Haim E., Bomben M., Bonneaud G.R., Calderini G., Chauveau J., Marchiori G., Ocariz J., Biasini M., Manoni E., Rossi A., Batignani G., Bettarini S., Carpinelli M., Casarosa G., Chrzaszcz M., Forti F., Giorgi M.A., Lusiani A., Oberhof B., Paoloni E., Rama M., Rizzo G., Walsh J.J., Zani L., Smith A.J.S., Anulli F., Faccini R., Ferrarotto F., Ferroni F., Pilloni A., Piredda G., Bunger C., Dittrich S., Grunberg O., Hess M., Leddig T., Voss C., Waldi R., Adye T., Wilson F.F., Emery S., Vasseur G., Aston D., Cartaro C., Convery M.R., Dorfan J., Dunwoodie W., Ebert M., Field R.C., Fulsom B.G., Graham M.T., Hast C., Innes W.R., Kim P., Leith D.W.G.S., Luitz S., Macfarlane D.B., Muller D.R., Neal H., Ratcliff B.N., Roodman A., Sullivan M.K., Va'Vra J., Wisniewski W.J., Purohit M.V., Wilson J.R., Randle-Conde A., Sekula S.J., Ahmed H., Bellis M., Burchat P.R., Puccio E.M.T., Alam M.S., Ernst J.A., Gorodeisky R., Guttman N., Peimer D.R., Soffer A., Spanier S.M., Ritchie J.L., Schwitters R.F., Izen J.M., Lou X.C., Bianchi F., De Mori F., Filippi A., Gamba D., Lanceri L., Vitale L., Martinez-Vidal F., Oyanguren A., Albert J., Beaulieu A., Bernlochner F.U., King G.J., Kowalewski R., Lueck T., Nugent I.M., Roney J.M., Sobie R.J., Tasneem N., Gershon T.J., Harrison P.F., Latham T.E., Prepost R., Wu S.L., Lees, J. P., Poireau, V., Tisserand, V., Grauges, E., Palano, A., Eigen, G., Brown, D. N., Kolomensky, Y. G., Fritsch, M., Koch, H., Schroeder, T., Cheaib, R., Hearty, C., Mattison, T. S., Mckenna, J. A., So, R. Y., Blinov, V. E., Buzykaev, A. R., Druzhinin, V. P., Golubev, V. B., Kozyrev, E. A., Kravchenko, E. A., Onuchin, A. P., Serednyakov, S. I., Skovpen, Y. I., Solodov, E. P., Todyshev, K. Y., Lankford, A. J., Dey, B., Gary, J. W., Long, O., Eisner, A. M., Lockman, W. S., Panduro Vazquez, W., Chao, D. S., Cheng, C. H., Echenard, B., Flood, K. T., Hitlin, D. G., Kim, J., Li, Y., Miyashita, T. S., Ongmongkolkul, P., Porter, F. C., Rohrken, M., Huard, Z., Meadows, B. T., Pushpawela, B. G., Sokoloff, M. D., Sun, L., Smith, J. G., Wagner, S. R., Bernard, D., Verderi, M., Bettoni, D., Bozzi, C., Calabrese, R., Cibinetto, G., Fioravanti, E., Garzia, I., Luppi, E., Santoro, V., Calcaterra, A., De Sangro, R., Finocchiaro, G., Martellotti, S., Patteri, P., Peruzzi, I. M., Piccolo, M., Rotondo, M., Zallo, A., Passaggio, S., Patrignani, C., Shuve, B. J., Lacker, H. M., Bhuyan, B., Mallik, U., Chen, C., Cochran, J., Prell, S., Gritsan, A. V., Arnaud, N., Davier, M., Le Diberder, F., Lutz, A. M., Wormser, G., Lange, D. J., Wright, D. M., Coleman, J. P., Gabathuler, E., Hutchcroft, D. E., Payne, D. J., Touramanis, C., Bevan, A. J., Di Lodovico, F., Sacco, R., Cowan, G., Banerjee, S., Davis, C. L., Denig, A. G., Gradl, W., Griessinger, K., Hafner, A., Schubert, K. R., Barlow, R. J., Lafferty, G. D., Cenci, R., Jawahery, A., Roberts, D. A., Cowan, R., Robertson, S. H., Seddon, R. M., Neri, N., Palombo, F., Cremaldi, L., Godang, R., Summers, D. J., Taras, P., De Nardo, G., Sciacca, C., Raven, G., Jessop, C. P., Losecco, J. M., Honscheid, K., Kass, R., Gaz, A., Margoni, M., Posocco, M., Simi, G., Simonetto, F., Stroili, R., Akar, S., Ben-Haim, E., Bomben, M., Bonneaud, G. R., Calderini, G., Chauveau, J., Marchiori, G., Ocariz, J., Biasini, M., Manoni, E., Rossi, A., Batignani, G., Bettarini, S., Carpinelli, M., Casarosa, G., Chrzaszcz, M., Forti, F., Giorgi, M. A., Lusiani, A., Oberhof, B., Paoloni, E., Rama, M., Rizzo, G., Walsh, J. J., Zani, L., Smith, A. J. S., Anulli, F., Faccini, R., Ferrarotto, F., Ferroni, F., Pilloni, A., Piredda, G., Bunger, C., Dittrich, S., Grunberg, O., Hess, M., Leddig, T., Voss, C., Waldi, R., Adye, T., Wilson, F. F., Emery, S., Vasseur, G., Aston, D., Cartaro, C., Convery, M. R., Dorfan, J., Dunwoodie, W., Ebert, M., Field, R. C., Fulsom, B. G., Graham, M. T., Hast, C., Innes, W. R., Kim, P., Leith, D. W. G. S., Luitz, S., Macfarlane, D. B., Muller, D. R., Neal, H., Ratcliff, B. N., Roodman, A., Sullivan, M. K., Va'Vra, J., Wisniewski, W. J., Purohit, M. V., Wilson, J. R., Randle-Conde, A., Sekula, S. J., Ahmed, H., Bellis, M., Burchat, P. R., Puccio, E. M. T., Alam, M. S., Ernst, J. A., Gorodeisky, R., Guttman, N., Peimer, D. R., Soffer, A., Spanier, S. M., Ritchie, J. L., Schwitters, R. F., Izen, J. M., Lou, X. C., Bianchi, F., De Mori, F., Filippi, A., Gamba, D., Lanceri, L., Vitale, L., Martinez-Vidal, F., Oyanguren, A., Albert, J., Beaulieu, A., Bernlochner, F. U., King, G. J., Kowalewski, R., Lueck, T., Nugent, I. M., Roney, J. M., Sobie, R. J., Tasneem, N., Gershon, T. J., Harrison, P. F., Latham, T. E., Prepost, R., and Wu, S. L.

Subjects
Physics, Particle physics, Kjerne- og elementærpartikkelfysikk: 431 [VDP], Meson, 010308 nuclear & particles physics, Electron–positron annihilation, General Physics and Astronomy, BaBar experiment, Bottom meson, BaBar, PEP-II, B meson, Bottom mesons, Branching (polymer chemistry), 7. Clean energy, 01 natural sciences, Lower limit, HEP, NO, Nuclear and elementary particle physics: 431 [VDP], 0103 physical sciences, 010306 general physics, Bar (unit)
Abstract

A study of the two-body decays B±→XccK±, where Xcc refers to one charmonium state, is reported by the BABAR Collaboration using a data sample of 424 fb-1. The absolute determination of branching fractions for these decays are significantly improved compared to previous BABAR measurements. Evidence is found for the decay B+→X(3872)K+ at the 3σ level. The absolute branching fraction B[B+→X(3872)K+]=[2.1±0.6(stat)±0.3(syst)]×10-4 is measured for the first time. It follows that B[X(3872)→J/ψπ+π-]=(4.1±1.3)%, supporting the hypothesis of a molecular component for this resonance., This work is supported by the U.S. Department of Energy and National Science Foundation, the Natural Sciences and Engineering Research Council (Canada), Institute of High Energy Physics (China), the Commissariat `a l’Energie Atomique and Institut National de Physique Nucl´eaire et de Physique des Particules (France), the Bundesministerium für Bildung und Forschung and Deutsche Forschungsgemeinschaft (Germany), the Istituto Nazionale di Fisica Nucleare (Italy), the Foundation for Fundamental Research on Matter (The Netherlands), the Research Council of Norway, the Ministry of Science and Technology of the Russian Federation, and the Particle Physics and Astronomy Research Council (United Kingdom). Individuals have received support from CONACyT (Mexico), the A. P. Sloan Foundation, the Research Corporation, and the Alexander von Humboldt Foundation.

Published
2020

32. Results from the CUORE experiment

Author

D. Q. Adams, C. Alduino, K. Alfonso, F. T. Avignone III, O. Azzolini, G. Bari, F. Bellini, G. Benato, M. Biassoni, A. Branca, C. Brofferio, C. Bucci, J. Camilleri, A. Caminata, A. Campani, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Cardani, P. Carniti, N. Casali, D. Chiesa, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, A. D'Addabbo, D. D'Aguanno, I. Dafinei, C. J. Davis, F. Del Corso, S. Dell'Oro, S. Di Domizio, V. Dompè, D. Q. Fang, G. Fantini, M. Faverzani, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, P. Gorla, C. Gotti, T. D. Gutierrez, K. Han, K. M. Heeger, R. G. Huang, H. Z. Huang, J. Johnston, G. Keppel, Yu. G. Kolomensky, C. Ligi, L. Ma, Y. G. Ma, L. Marini, R. H. Maruyama, Y. Mei, N. Moggi, S. Morganti, T. Napolitano, M. Nastasi, J. Nikkel, C. Nones, E. B. Norman, V. Novati, A. Nucciotti, I. Nutini, T. O'Donnell, J. L. Ouellet, C. E. Pagliarone, L. Pagnanini, M. Pallavicini, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, C. Pira, S. Pirro, S. Pozzi, E. Previtali, A. Puiu, C. Rosenfeld, C. Rusconi, M. Sakai, S. Sangiorgio, B. Schmidt, N. D. Scielzo, V. Singh, M. Sisti, D. Speller, L. Taffarello, F. Terranova, C. Tomei, M. Vignati, S. L. Wagaarachchi, B. S. Wang, B. Welliver, J. Wilson, K. Wilson, L. A. Winslow, L. Zanotti, S. Zimmermann, S. Zucchelli, Adams, D, Alduino, C, Alfonso, K, Avignone III, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Del Corso, F, Dell'Oro, S, Di Domizio, S, Dompè, V, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Huang, R, Huang, H, Johnston, J, Keppel, G, Kolomensky, Y, Ligi, C, Ma, L, Ma, Y, Marini, L, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, N, Singh, V, Sisti, M, Speller, D, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Zanotti, L, Zimmermann, S, and Zucchelli, S

Subjects
neutrinoless double beta decay
Published
2020

33. Stability and efficiency of a CMOS sensor as detector of low energy beta and gamma particles

Author

M. De Simoni, Franco Meddi, E. Solfaroli Camillocci, Riccardo Faccini, Á. Tóth, V. Bocci, M. Fischetti, Francesco Collamati, R. Mirabelli, C. Campeggi, Maurizio Biasini, C. Mancini Terracciano, R. Amoruso, M. Ionica, L. Servoli, Gaia Franciosini, K. Kanxheri, S. Morganti, L. Alunni Solestizi, and P. De Maria

Subjects
CMOS sensor, Materials science, business.industry, Detector, Image reconstruction in medical imaging, Stability (probability), Particle detector, Calculation methods, 3. Good health, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Low energy, radio-guided surgery, 030220 oncology & carcinogenesis, Intra-operative probes, Measuring instrument, Optoelectronics, business, Instrumentation, Sensitivity (electronics), Mathematical Physics
Abstract

Radio Guided Surgery (RGS) is a nuclear medicine technique allowing the surgeon to identify tumor residuals in real time with a millimetric resolution, thanks to a radiopharmaceutical as tracer and a probe as detector. The use of beta(-) emitters, instead of gamma or beta(+), has been recently proposed with the aim to increase the technique sensitivity and reducing both the administered activity to the patient and the medical exposure. In this paper, the possibility to use the commercial CMOS Image Sensor MT9V115, originally designed for visible light imaging, as beta(-) radiation detector RGS is discussed. Being crucial characteristics in a surgical environment, in particular its stability against time, operating temperature, integration time and gain has been studied on laboratory measurements. Moreover, a full Monte Carlo simulation of the detector has been developed. Its validation against experimental data allowed us to obtain efficiency curves for both beta and gamma particles, and also to evaluate the effect of the covering heavy resin protective layer that is present in the "off the shelf" detector. This study suggests that a dedicated CMOS Image Sensor (i.e. one produced without the covering protective layer) represents the ideal candidate detector for RGS, able to massively increase the amount of application cases and the efficacy of this technique.

Published
2020

34. Lowering the Energy Threshold of the CUORE Experiment: Benefits in the Surface Alpha Events Reconstruction: Comparison Between Optimum Trigger and Derivative Trigger Performance in the Search for 0 νββ

Author

L. Pattavina, Marco Pallavicini, L. Canonica, L. Marini, S. Di Domizio, C. Bucci, T. D. Gutierrez, G. Pessina, K. Wilson, Stefano Dell'Oro, Jonathan Ouellet, J. Johnston, G. Bari, Laura Cardani, L. Zanotti, J. Nikkel, L. Gironi, F. T. Avignone, H. Z. Huang, B. K. Fujikawa, G. Keppel, Stefano Pozzi, Y. G. Ma, Massimiliano Clemenza, Carlo Cosmelli, Davide Chiesa, C. Nones, A. Puiu, V. Pettinacci, S. Zucchelli, N. D. Scielzo, L. Pagnanini, C. Brofferio, T. O'Donnell, D. Q. Fang, Claudio Gotti, Ke Han, Reina H. Maruyama, M. Vignati, C. Rusconi, Stuart J. Freedman, D. D'Aguanno, Ettore Fiorini, V. Novati, James R. Wilson, Andrea Giachero, C. Rosenfeld, P. Gorla, F. Ferroni, C. Tomei, M. A. Franceschi, C. Pagliarone, D. Q. Adams, R. G. Huang, N. Casali, F. Terranova, Vasundhara Singh, K. Alfonso, C. J. Davis, Monica Sisti, B. Schmidt, Eric B. Norman, B. S. Wang, L. Ma, O. Azzolini, Y. Mei, Lindley Winslow, V. Sharma, T. Napolitano, S. Copello, I. Dafinei, M. Sakai, Paolo Carniti, Silvia Capelli, Xi-Guang Cao, Massimiliano Nastasi, K. M. Heeger, F. Bellini, S. Pirro, L. Cappelli, Oliviero Cremonesi, M. Biassoni, R. J. Creswick, G. Fantini, M. Pavan, V. Dompè, Giovanni Benato, A. D'Addabbo, C. Pira, A. Caminata, Ezio Previtali, S. Morganti, B. Welliver, Carlo Ligi, Evelyn Ferri, N. Moggi, Samuele Sangiorgio, A. Campani, A. Nucciotti, C. Alduino, M. Faverzani, Yu. G. Kolomensky, A. Branca, L. Taffarello, A. Giuliani, Danielle Speller, S. L. Wagaarachchi, N. Chott, Irene Nutini, S. Zimmermann, Campani, A, Adams, D, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Dell'Oro, S, Di Domizio, S, Dompe, V, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Huang, R, Huang, H, Johnston, J, Keppel, G, Kolomensky, Y, Ligi, C, Ma, Y, Ma, L, Marini, L, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, N, Sharma, V, Singh, V, Sisti, M, Speller, D, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Zanotti, L, Zimmermann, S, Zucchelli, S, Campani A., Adams D.Q., Alduino C., Alfonso K., Avignone F.T., Azzolini O., Bari G., Bellini F., Benato G., Biassoni M., Branca A., Brofferio C., Bucci C., Caminata A., Canonica L., Cao X.G., Capelli S., Cappelli L., Cardani L., Carniti P., Casali N., Chiesa D., Chott N., Clemenza M., Copello S., Cosmelli C., Cremonesi O., Creswick R.J., D'Addabbo A., D'Aguanno D., Dafinei I., Davis C.J., Dell'Oro S., Di Domizio S., Dompe V., Fang D.Q., Fantini G., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M.A., Freedman S.J., Fujikawa B.K., Giachero A., Gironi L., Giuliani A., Gorla P., Gotti C., Gutierrez T.D., Han K., Heeger K.M., Huang R.G., Huang H.Z., Johnston J., Keppel G., Kolomensky Y.G., Ligi C., Ma Y.G., Ma L., Marini L., Maruyama R.H., Mei Y., Moggi N., Morganti S., Napolitano T., Nastasi M., Nikkel J., Nones C., Norman E.B., Novati V., Nucciotti A., Nutini I., O'Donnell T., Ouellet J.L., Pagliarone C.E., Pagnanini L., Pallavicini M., Pattavina L., Pavan M., Pessina G., Pettinacci V., Pira C., Pirro S., Pozzi S., Previtali E., Puiu A., Rosenfeld C., Rusconi C., Sakai M., Sangiorgio S., Schmidt B., Scielzo N.D., Sharma V., Singh V., Sisti M., Speller D., Taffarello L., Terranova F., Tomei C., Vignati M., Wagaarachchi S.L., Wang B.S., Welliver B., Wilson J., Wilson K., Winslow L.A., Zanotti L., Zimmermann S., and Zucchelli S.

Subjects
Particle physics, Bolometers for dark matter research, Physics::Instrumentation and Detectors, trigger algorithm, 01 natural sciences, Coincidence, law.invention, CUORE, WIMP, law, Double beta decay, 0103 physical sciences, General Materials Science, Neutrinoless double beta decay, 010306 general physics, Axion, Physics, 010308 nuclear & particles physics, Scattering, Bolometer, Astrophysics::Instrumentation and Methods for Astrophysics, Trigger algorithms, Condensed Matter Physics, Digital signal processing, Atomic and Molecular Physics, and Optics, Energy (signal processing)
Abstract

CUORE is a tonne-scale cryogenic experiment located at the Laboratori Nazionali del Gran Sasso that exploits bolometric technique to search for neutrinoless double beta decay of 130Te. Thanks to its very low background and large mass, CUORE is also a powerful tool to study a broad class of phenomena, such as solar axions and WIMP scattering. The ability to conduct such sensitive searches crucially depends on the energy threshold, which has to be kept as low as possible. In this contribution, we show how the trigger algorithm affects the sensitivity to low-energy phenomena and the interpretation of the energy spectrum. In particular, we focus on the impact that the trigger algorithm has on the identification of the coincidence events among different crystals and, consequently, on the reconstruction of the background.

Published
2020

35. Status and results from the CUORE experiment

Author

C. Bucci, T. D. Gutierrez, Silvia Capelli, Massimiliano Nastasi, C. Pira, L. Gironi, F. T. Avignone, X. G. Cao, S. Di Domizio, V. Dompè, L. Taffarello, Danielle Speller, L. Cappelli, Laura Cardani, H. Z. Huang, M. Pavan, M. A. Franceschi, B. K. Fujikawa, Stefano Pozzi, Carlo Ligi, C. Pagliarone, Y. Mei, Massimiliano Clemenza, Carlo Cosmelli, Stefano Dell'Oro, A. D’Addabbo, M. Vignati, Lindley Winslow, A. Campani, S. Zucchelli, G. Keppel, K. Wilson, Davide Chiesa, Claudio Gotti, R. G. Huang, M. Faverzani, Jonathan Ouellet, G. Bari, A. Branca, C. Brofferio, L. Ma, Deqing Fang, S. Pirro, C. Rusconi, N. Casali, A. Caminata, Ezio Previtali, S. Zimmermann, S. L. Wagaarachchi, S. Morganti, T. O'Donnell, B. Welliver, K. M. Heeger, G. Fantini, C. Nones, A. Puiu, V. Pettinacci, V. Sharma, D. D'Aguanno, J. Nikkel, N. Chott, Oliviero Cremonesi, Marco Pallavicini, G. Pessina, A. Giuliani, Yu. G. Kolomensky, Ke Han, Reina H. Maruyama, C. Rosenfeld, Stuart J. Freedman, P. Gorla, F. Ferroni, C. Tomei, C. J. Davis, L. Zanotti, Irene Nutini, Evelyn Ferri, Yu-Gang Ma, F. Terranova, N. Moggi, Samuele Sangiorgio, P. T. Surukuchi, A. Nucciotti, L. Pagnanini, C. Alduino, S. Copello, Paolo Carniti, Ettore Fiorini, V. Novati, Andrea Giachero, D. Q. Adams, K. Alfonso, L. Pattavina, N. D. Scielzo, L. Canonica, L. Marini, Vasundhara Singh, J. Johnston, B. Schmidt, B. S. Wang, O. Azzolini, I. Dafinei, M. Sakai, James R. Wilson, F. Bellini, Monica Sisti, R. J. Creswick, Giovanni Benato, Eric B. Norman, T. Napolitano, M. Biassoni, Campani, A, Adams, D, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Dell'Oro, S, Di Domizio, S, Dompe, V, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Huang, R, Huang, H, Johnston, J, Keppel, G, Kolomensky, Y, Ligi, C, Ma, Y, Ma, L, Marini, L, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, N, Sharma, V, Singh, V, Sisti, M, Speller, D, Surukuchi, P, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Zanotti, L, Zimmermann, S, Zucchelli, S, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPhP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, CUORE, and Département de Physique des Particules (ex SPP) (DPP)

Subjects
Nuclear and High Energy Physics, data analysis method, background: model, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 01 natural sciences, Combinatorics, CUORE, double-beta decay: (0neutrino), bolometer, 0103 physical sciences, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Neutrinoless double beta decay, 010306 general physics, activity report, Physics, 010308 nuclear & particles physics, 29.90.+r, Astronomy and Astrophysics, Background model, Atomic and Molecular Physics, and Optics, tellurium: nuclide, data management, Two-neutrino double beta decay, background model, two-neutrino double beta decay, experimental results
Abstract

Author(s): Campani, A; Adams, DQ; Alduino, C; Alfonso, K; Avignone, FT; Azzolini, O; Bari, G; Bellini, F; Benato, G; Biassoni, M; Branca, A; Brofferio, C; Bucci, C; Caminata, A; Canonica, L; Cao, XG; Capelli, S; Cappelli, L; Cardani, L; Carniti, P; Casali, N; Chiesa, D; Chott, N; Clemenza, M; Copello, S; Cosmelli, C; Cremonesi, O; Creswick, RJ; D'Addabbo, A; D'Aguanno, D; Dafinei, I; Davis, CJ; Dell'oro, S; Di Domizio, S; Dompe, V; Fang, DQ; Fantini, G; Faverzani, M; Ferri, E; Ferroni, F; Fiorini, E; Franceschi, MA; Freedman, SJ; Fujikawa, BK; Giachero, A; Gironi, L; Giuliani, A; Gorla, P; Gotti, C; Gutierrez, TD; Han, K; Heeger, KM; Huang, RG; Huang, HZ; Johnston, J; Keppel, G; Kolomensky, YG; Ligi, C; Ma, YG; Ma, L; Marini, L; Maruyama, RH; Mei, Y; Moggi, N; Morganti, S; Napolitano, T; Nastasi, M; Nikkel, J; Nones, C; Norman, EB; Novati, V; Nucciotti, A; Nutini, I; O'Donnell, T; Ouellet, JL; Pagliarone, CE; Pagnanini, L; Pallavicini, M; Pattavina, L; Pavan, M; Pessina, G; Pettinacci, V; Pira, C; Pirro, S; Pozzi, S | Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is a tonne-scale cryogenic experiment located at the Laboratori Nazionali del Gran Sasso that exploits bolometric technique to search for neutrinoless double beta decay (0νββ) of 130Te. The detector consists of a segmented array of 988 natural TeO2 cubic crystals arranged in a cylindrical compact structure of 19 towers. The detector construction was completed in August 2016 and data taking started in Spring 2017. In this work, we present a brief description of the bolometric technique for rare events search and the CUORE detector, then we concentrate on the data analysis results. In this respect, we focus on the procedure for data processing and on the first 0νββ results we obtained from a total TeO2 exposure of 86.3kg yr. Next, we illustrate the main background sources and the CUORE background model, from which we obtain the most precise measurement of 130Te 2νββ half-life to date. Finally, we discuss the improvements achieved with 2018 and 2019 detector optimization campaigns and the current perspectives of our experiment.

Published
2020

36. Feasibility study on the use of CMOS sensors as detectors in radioguided surgery with β

Author

A. Capotosti, C. Mancini Terracciano, Maurizio Biasini, Francesco Collamati, R. Mirabelli, Franco Meddi, M. Ionica, V. Bocci, M. Marafini, R. Amoruso, Pisana Placidi, L. Alunni Solestizi, E. Solfaroli Camillocci, L. Servoli, S. Morganti, C. Campeggi, Andrea Scorzoni, R. Faccini, S. Mantini, and K. Kanxheri

Subjects
010403 inorganic & nuclear chemistry, 01 natural sciences, Concentration ratio, Signal, Imaging phantom, Collimated light, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Optics, Dimension (vector space), Neoplasms, Humans, Physics, Radiation, business.industry, Resolution (electron density), Detector, CMOS sensors Radioguided surgery − radiation, 0104 chemical sciences, Beta Particles, CMOS, Surgery, Computer-Assisted, Feasibility Studies, Radiopharmaceuticals, business
Abstract

Radioguided surgery (RGS) is a medical practice which thanks to a radiopharmaceutical tracer and a probe allows the surgeon to identify tumor residuals up to a millimetric resolution in real-time. The employment of β − emitters, instead of γ or β + , reduces background from healthy tissues, administered activity to the patient, and medical exposure. In a previous work the possibility of using a CMOS Imager (Aptina MT9V011), initially designed for visible light imaging, to detect β − from 90Y or 90Sr sources has been established. Because of its possible application as counting probe in RGS, the performances of MT9V011 in clinical-like conditions were studied. 1 Through horizontal scans on a collimated 90Sr source of different sizes (1, 3, 5, 7 mm), we have determined relationships between scan fit parameters and the source dimension, namely A quadratic correlation and a linear dependency of, respectively, signal integrated over scan interval, and maximum signal against source diameter, are determined. Horizontal scan measurements on a source, interposing collimators of different size, aim to determine relationships or correlations between scan fit parameters and source dimension. A quadratic correlation and a linear dependency of, respectively, signal integrated over scan interval, and maximum signal against source diameter are determined. In order to get closer to clinical conditions, agar–agar phantoms containing 90 Y with different dimensions and activities were prepared. A 90 Y phantom is characterized by a central spot and a ring all around, for simulating both signal (tumor) and background (surrounding healthy tissue). The relationship found between scan maximum and 90 S r source diameter is then exploited to extract the concentration ratio between spot and external ring of the 90 Y phantom. This observable, defined as the ratio between the tumor and the nearby healthy tissues uptake simulates the Tumor-to-Non-tumor Ratio (TNR). With the aim of evaluating the sensor’s ability to discriminate signal from background relying on the significance parameter, a further 90 Y phantom, featuring a well-known and clinical-like activity will mimic the signal only condition. This result is used to extrapolate to different source sizes, after having estimated the background for various TNR. The obtained significance values suggest that the MT9V011 sensor is capable of distinguishing a signal from an estimated background, depending on the interplay among TNR, acquisition time and tumor diameter.

Published
2019

37. The CUORE Detector and Results

Author

James R. Wilson, C. Rosenfeld, S. Morganti, N. D. Scielzo, Carlo Ligi, V. Dompè, A. D'Addabbo, A. Campani, P. Gorla, F. Ferroni, C. Tomei, Monica Sisti, S. Copello, S. L. Wagaarachchi, J. Nikkel, L. Zanotti, Paolo Carniti, C. Pira, M. Faverzani, N. Casali, N. Chott, Simone Capelli, C. J. Davis, Giovanni Benato, H. Z. Huang, G. Keppel, L. Gironi, Ettore Fiorini, F. Terranova, G. Fantini, C. Nones, A. Puiu, S. Zucchelli, V. Novati, Andrea Giachero, Massimiliano Clemenza, Carlo Cosmelli, F. T. Avignone, Irene Nutini, Yu. G. Kolomensky, Massimiliano Nastasi, L. Canonica, L. Marini, V. Pettinacci, K. Wilson, Eric B. Norman, T. O'Donnell, D. Q. Adams, Vasundhara Singh, Jonathan Ouellet, K. Alfonso, S. Di Domizio, J. Johnston, Claudio Gotti, G. Bari, Y. Mei, D. D'Aguanno, T. Napolitano, Evelyn Ferri, Laura Cardani, L. Taffarello, Stefano Dell'Oro, B. K. Fujikawa, Stefano Pozzi, F. Bellini, B. Schmidt, Y. G. Ma, Oliviero Cremonesi, M. Biassoni, Danielle Speller, B. S. Wang, Xi-Guang Cao, C. Brofferio, M. Vignati, M. Pavan, L. Pagnanini, K. M. Heeger, Davide Chiesa, O. Azzolini, N. Moggi, Marco Pallavicini, C. Rusconi, C. Bucci, T. D. Gutierrez, R. J. Creswick, Samuele Sangiorgio, Lindley Winslow, A. Giuliani, Ke Han, Reina H. Maruyama, I. Dafinei, M. Sakai, G. Pessina, Stuart J. Freedman, L. Pattavina, A. Nucciotti, C. Alduino, S. Zimmermann, S. Pirro, L. Ma, D. Q. Fang, A. Branca, M. A. Franceschi, R. G. Huang, L. Cappelli, C. Pagliarone, A. Caminata, Ezio Previtali, B. Welliver, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Nutini, I, Adams, D, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, C, Dell’Oro, S, Domizio, S, Dompè, V, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Huang, R, Huang, H, Johnston, J, Keppel, G, Kolomensky, Y, Ligi, C, Ma, Y, Ma, L, Marini, L, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, E, Novati, V, Nucciotti, A, O’Donnell, T, Ouellet, J, Pagliarone, C, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, N, Singh, V, Sisti, M, Speller, D, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Zanotti, L, Zimmermann, S, Zucchelli, S, Nutini I., Adams D.Q., Alduino C., Alfonso K., Avignone F.T., Azzolini O., Bari G., Bellini F., Benato G., Biassoni M., Branca A., Brofferio C., Bucci C., Caminata A., Campani A., Canonica L., Cao X.G., Capelli S., Cappelli L., Cardani L., Carniti P., Casali N., Chiesa D., Chott N., Clemenza M., Copello S., Cosmelli C., Cremonesi O., Creswick R.J., D'Addabbo A., D'Aguanno D., Dafinei I., Davis C.J., Dell'Oro S., Domizio S.D., Dompe V., Fang D.Q., Fantini G., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M.A., Freedman S.J., Fujikawa B.K., Giachero A., Gironi L., Giuliani A., Gorla P., Gotti C., Gutierrez T.D., Han K., Heeger K.M., Huang R.G., Huang H.Z., Johnston J., Keppel G., Kolomensky Y.G., Ligi C., Ma Y.G., Ma L., Marini L., Maruyama R.H., Mei Y., Moggi N., Morganti S., Napolitano T., Nastasi M., Nikkel J., Nones C., Norman E.B., Novati V., Nucciotti A., O'Donnell T., Ouellet J.L., Pagliarone C.E., Pagnanini L., Pallavicini M., Pattavina L., Pavan M., Pessina G., Pettinacci V., Pira C., Pirro S., Pozzi S., Previtali E., Puiu A., Rosenfeld C., Rusconi C., Sakai M., Sangiorgio S., Schmidt B., Scielzo N.D., Singh V., Sisti M., Speller D., Taffarello L., Terranova F., Tomei C., Vignati M., Wagaarachchi S.L., Wang B.S., Welliver B., Wilson J., Wilson K., Winslow L.A., Zanotti L., Zimmermann S., Zucchelli S., and Département de Physique des Particules (ex SPP) (DPhP)

Subjects
Particle physics, 0 νββ, Cryogenics, CUORE, Macro-calorimeters, Neutrinos, Physics::Instrumentation and Detectors, Cryogenic, 01 natural sciences, tellurium: oxygen, 010305 fluids & plasmas, crystal, double-beta decay: (0neutrino), Double beta decay, 0103 physical sciences, Neutrino, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], General Materials Science, Beta (velocity), [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, activity report, detector: design, Physics, 0νββ, 0 nu beta beta, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Condensed Matter Physics, Atomic and Molecular Physics, and Optics, High Energy Physics::Experiment, tellurium: nuclide, Macro-calorimeter, experimental results
Abstract

The cryogenic underground observatory for rare events (CUORE) is a cryogenic experiment searching for neutrinoless double beta decay ($$0\nu \beta \beta$$0νββ) of $${^{130}\hbox {Te}}$$130Te. The detector consists of an array of $$988\,{\hbox {TeO}_{2}}$$988TeO2 crystals arranged in a compact cylindrical structure of 19 towers. We report the CUORE initial operations and optimization campaigns. We then present the CUORE results on $$0\nu \beta \beta$$0νββ and $$2\nu \beta \beta$$2νββ decay of $${^{130}\hbox {Te}}$$130Te obtained from the analysis of the physics data acquired in 2017.

Published
2019

38. CUORE: The first bolometric experiment at the ton scale for the search for neutrino-less double beta decay

Author

James R. Wilson, N. Moggi, Monica Sisti, Carlo Cosmelli, Samuele Sangiorgio, Lindley Winslow, Jeremy S. Cushman, C. Rosenfeld, A. Nucciotti, Claudio Gotti, C. Alduino, C. Bucci, T. D. Gutierrez, S. Copello, V. Pettinacci, P. Gorla, F. Ferroni, C. Tomei, C. Brofferio, M. Faverzani, Stefano Pirro, D. D'Aguanno, S. Morganti, Paolo Carniti, A. Giuliani, Davide Chiesa, C. Rusconi, C. J. Davis, I. Dafinei, M. Sakai, M. Pavan, S. Zucchelli, K. Wilson, Y. Mei, N. Chott, S. Di Domizio, L. Cappelli, Eric B. Norman, T. Napolitano, V. Dompè, Oliviero Cremonesi, Jonathan Ouellet, G. Bari, A. D'Addabbo, Stefano Dell'Oro, M. Clemenza, Laura Cardani, T. Wise, D. Q. Fang, B. K. Fujikawa, Vasundhara Singh, Stefano Pozzi, Xi-Guang Cao, H. Z. Huang, K. M. Heeger, G. Keppel, M. Biassoni, L. Taffarello, C. Pagliarone, S. Zimmermann, Marco Pallavicini, T. O'Donnell, A. Caminata, Carlo Ligi, Yu. G. Kolomensky, Ezio Previtali, G. Pessina, B. Schmidt, Danielle Speller, B. S. Wang, B. Welliver, M. Vignati, O. Azzolini, Irene Nutini, Ettore Fiorini, V. Novati, Andrea Giachero, A. Campani, C. Pira, L. Pattavina, A. Drobizhev, Silvia Capelli, C. Nones, A. Puiu, F. Terranova, Yu-Gang Ma, Massimiliano Nastasi, D. Q. Adams, K. Alfonso, N. Casali, Giovanni Benato, M. A. Franceschi, G. Fantini, A. Branca, R. G. Huang, Ke Han, Reina H. Maruyama, Stuart J. Freedman, S. L. Wagaarachchi, L. Gironi, F. T. Avignone, A. Bersani, R. J. Creswick, F. Bellini, A. Leder, N. D. Scielzo, L. Zanotti, L. Canonica, L. Marini, J. Johnston, Evelyn Ferri, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Adams D.Q., Alduino C., Alfonso K., Avignone F.T., Azzolini O., Bari G., Bellini F., Benato G., Bersani A., Biassoni M., Branca A., Brofferio C., Bucci C., Caminata A., Campani A., Canonica L., Cao X.G., Capelli S., Cappelli L., Cardani L., Carniti P., Casali N., Chiesa D., Chott N., Clemenza M., Copello S., Cosmelli C., Cremonesi O., Creswick R.J., Cushman J.S., D'Addabbo A., D'Aguanno D., Dafinei I., Davis C.J., Dell'Oro S., Di Domizio S., Dompe V., Drobizhev A., Fang D.Q., Fantini G., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M.A., Freedman S.J., Fujikawa B.K., Giachero A., Gironi L., Giuliani A., Gorla P., Gotti C., Gutierrez T.D., Han K., Heeger K.M., Huang R.G., Huang H.Z., Johnston J., Keppel G., Kolomensky Y.G., Leder A., Ligi C., Ma Y.G., Marini L., Maruyama R.H., Mei Y., Moggi N., Morganti S., Napolitano T., Nastasi M., Nones C., Norman E.B., Novati V., Nucciotti A., Nutini I., O'Donnell T., Ouellet J.L., Pagliarone C.E., Pallavicini M., Pattavina L., Pavan M., Pessina G., Pettinacci V., Pira C., Pirro S., Pozzi S., Previtali E., Puiu A., Rosenfeld C., Rusconi C., Sakai M., Sangiorgio S., Schmidt B., Scielzo N.D., Singh V., Sisti M., Speller D., Taffarello L., Terranova F., Tomei C., Vignati M., Wagaarachchi S.L., Wang B.S., Welliver B., Wilson J., Wilson K., Winslow L.A., Wise T., Zanotti L., Zimmermann S., Zucchelli S., Département de Physique des Particules (ex SPP) (DPhP), Adams, D, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Dell'Oro, S, Di Domizio, S, Dompe, V, Drobizhev, A, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Huang, R, Huang, H, Johnston, J, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Ma, Y, Marini, L, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, N, Singh, V, Sisti, M, Speller, D, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zimmermann, S, and Zucchelli, S

Subjects
Cryostat, Nuclear and High Energy Physics, Physics::Instrumentation and Detectors, Dark matter, energy resolution, 01 natural sciences, tellurium: oxygen, law.invention, Nuclear physics, energy: threshold, CUORE, Bolometers, Neutrinoless double beta decay, Ton-scale detector, double-beta decay: (0neutrino), bolometer, law, Observatory, Double beta decay, 0103 physical sciences, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, Instrumentation, activity report, background: suppression, detector: design, Neutrinoless double beta decay, Ton-scale detector, Bolometers, Physics, 010308 nuclear & particles physics, Bolometer, Detector, sensitivity, cryogenics, High Energy Physics::Experiment, Neutrino, performance
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is the most massive bolometric experiment searching for neutrino-less double beta (0 ν β β ) decay. The detector consists of an array of 988 TeO 2 crystals (742 kg) arranged in a compact cylindrical structure of 19 towers. This paper will describe the CUORE experiment, including the cryostat, and present the detector performance during the first year of running. Additional detail will describe the effort made in improving the energy resolution in the 130Te 0 ν β β decay region of interest (ROI) and the suppression of backgrounds. A description of work to lower the energy threshold in order to give CUORE the sensitivity to search for other rare events, such as dark matter, will also be provided.

Published
2019

39. CUORE: The first bolometric experiment at the ton scale for rare decay searches

Author

A. Bersani, L. Pattavina, Oliviero Cremonesi, Massimiliano Clemenza, Carlo Cosmelli, C. Pagliarone, C. Rosenfeld, P. Gorla, H. Z. Huang, G. Keppel, F. Ferroni, C. Tomei, K. Wilson, V. Palmieri, C. Nones, Eric B. Norman, A. Puiu, Jonathan Ouellet, G. Bari, Claudio Gotti, T. Napolitano, C. Brofferio, L. Gironi, F. T. Avignone, C. J. Davis, A. Caminata, Ezio Previtali, B. Welliver, S. Copello, Guoqiang Zhang, Lorenzo Cassina, Evelyn Ferri, Paolo Carniti, L. Canonica, A. Giuliani, S. Di Domizio, M. M. Deninno, Davide Chiesa, L. Marini, C. Rusconi, Ettore Fiorini, M. Biassoni, N. Moggi, V. Novati, Andrea Giachero, F. Bellini, S. Zimmermann, Laura Cardani, J. Johnston, Ke Han, A. Branca, B. K. Fujikawa, Stefano Pozzi, L. Gladstone, D. Q. Adams, K. Alfonso, M. L. Di Vacri, Reina H. Maruyama, Samuele Sangiorgio, Stuart J. Freedman, C. Bucci, S. L. Wagaarachchi, T. D. Gutierrez, Miriam Lucio Martinez, Stefano Dell'Oro, R. Hennings-Yeomans, A. Nucciotti, R. J. Creswick, Stefano Pirro, N. Chott, D. D'Aguanno, C. Alduino, M. Vignati, M. Faverzani, S. Zucchelli, L. Cappelli, Giovanni Benato, N. Casali, Marco Pallavicini, Irene Nutini, Yu. G. Kolomensky, G. Pessina, S. Morganti, F. Terranova, Yu-Gang Ma, F. Reindl, H. W. Wang, T. O'Donnell, S. S. Nagorny, Y. Mei, Lindley Winslow, V. Dompè, M. Sakai, Xi-Guang Cao, A. D'Addabbo, K. M. Heeger, Carlo Ligi, N. D. Scielzo, A. Campani, T. Wise, L. Taffarello, Danielle Speller, L. Zanotti, I. Dafinei, C. Pira, A. Leder, D. Santone, Vasundhara Singh, B. Schmidt, B. S. Wang, D. Q. Fang, O. Azzolini, A. Drobizhev, Jeremy S. Cushman, M. A. Franceschi, R. G. Huang, Silvia Capelli, Massimiliano Nastasi, M. Pavan, James R. Wilson, Monica Sisti, Adams D.Q., Alduino C., Alfonso K., Avignone F.T., Azzolini O., Bari G., Bellini F., Benato G., Bersani A., Biassoni M., Branca A., Brofferio C., Bucci C., Caminata A., Campani A., Canonica L., Cao X.G., Capelli S., Cappelli L., Cardani L., Carniti P., Casali N., Cassina L., Chiesa D., Chott N., Clemenza M., Copello S., Cosmelli C., Cremonesi O., Creswick R.J., Cushman J.S., D'Addabbo A., D'Aguanno D., Dafinei I., Davis C.J., Dell'Oro S., Deninno M.M., Domizio S.D., Vacri M.L.D., Dompe V., Drobizhev A., Fang D.Q., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M.A., Freedman S.J., Fujikawa B.K., Giachero A., Gironi L., Giuliani A., Gladstone L., Gorla P., Gotti C., Gutierrez T.D., Han K., Heeger K.M., Hennings-Yeomans R., Huang R.G., Huang H.Z., Johnston J., Keppel G., Kolomensky Y.G., Leder A., Ligi C., Ma Y.G., Marini L., Martinez M., Maruyama R.H., Mei Y., Moggi N., Morganti S., Nagorny S.S., Napolitano T., Nastasi M., Nones C., Norman E.B., Novati V., Nucciotti A., Nutini I., O'Donnell T., Ouellet J.L., Pagliarone C.E., Pallavicini M., Palmieri V., Pattavina L., Pavan M., Pessina G., Pira C., Pirro S., Pozzi S., Previtali E., Puiu A., Reindl F., Rosenfeld C., Rusconi C., Sakai M., Sangiorgio S., Santone D., Schmidt B., Scielzo N.D., Singh V., Sisti M., Speller D., Taffarello L., Terranova F., Tomei C., Vignati M., Wagaarachchi S.L., Wang B.S., Wang H.W., Welliver B., Wilson J., Wilson K., Winslow L.A., Wise T., Zanotti L., Zhang G.Q., Zimmermann S., Zucchelli S., Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Département de Physique des Particules (ex SPP) (DPhP), Adams, D, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, C, Dell’Oro, S, Deninno, M, Domizio, S, Vacri, M, Dompè, V, Drobizhev, A, Fang, D, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Hennings-Yeomans, R, Huang, R, Huang, H, Johnston, J, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Ma, Y, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Nagorny, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O’Donnell, T, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Scielzo, N, Singh, V, Sisti, M, Speller, D, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zhang, G, Zimmermann, S, and Zucchelli, S

Subjects
Nuclear and High Energy Physics, Cryogenic, Superconductive Devices, Physics::Instrumentation and Detectors, Cryogenic, 01 natural sciences, tellurium: oxygen, Combinatorics, CUORE, bolometer, double-beta decay: (0neutrino), Superconductive Devices, 0103 physical sciences, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, Instrumentation, detector: design, activity report, Physics, 010308 nuclear & particles physics, Astrophysics::Instrumentation and Methods for Astrophysics, Superconductive Device, cryogenics, Physics::Accelerator Physics, High Energy Physics::Experiment, performance
Abstract

Author(s): Adams, DQ; Alduino, C; Alfonso, K; Avignone, FT; Azzolini, O; Bari, G; Bellini, F; Benato, G; Bersani, A; Biassoni, M; Branca, A; Brofferio, C; Bucci, C; Caminata, A; Campani, A; Canonica, L; Cao, XG; Capelli, S; Cappelli, L; Cardani, L; Carniti, P; Casali, N; Cassina, L; Chiesa, D; Chott, N; Clemenza, M; Copello, S; Cosmelli, C; Cremonesi, O; Creswick, RJ; Cushman, JS; D'Addabbo, A; D'Aguanno, D; Dafinei, I; Davis, CJ; Dell'Oro, S; Deninno, MM; Domizio, SD; Vacri, MLD; Dompe, V; Drobizhev, A; Fang, DQ; Faverzani, M; Ferri, E; Ferroni, F; Fiorini, E; Franceschi, MA; Freedman, SJ; Fujikawa, BK; Giachero, A; Gironi, L; Giuliani, A; Gladstone, L; Gorla, P; Gotti, C; Gutierrez, TD; Han, K; Heeger, KM; Hennings-Yeomans, R; Huang, RG; Huang, HZ; Johnston, J; Keppel, G; Kolomensky, YG; Leder, A; Ligi, C; Ma, YG; Marini, L; Martinez, M; Maruyama, RH; Mei, Y; Moggi, N; Morganti, S; Nagorny, SS; Napolitano, T; Nastasi, M; Nones, C; Norman, EB; Novati, V; Nucciotti, A; Nutini, I; O'Donnell, T; Ouellet, JL; Pagliarone, CE; Pallavicini, M | Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta decay that has been able to reach the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. The construction of the experiment and, in particular, the installation of all towers in the cryostat was completed in August 2016 and data taking started in spring 2017. In this contribution the achievement of the commissioning phase and the performance of the detector and the cryostat during the first physics run will be presented.

Published
2019

40. CUPID-0: A double-readout cryogenic detector for Double Beta Decay search

Author

D. Orlandi, Davide Chiesa, C. Brofferio, Jeffrey W. Beeman, G. Keppel, S. Di Domizio, C. Rusconi, M. Clemenza, Laura Cardani, K. Schäffner, Stefano Pozzi, L. Pattavina, M. Vignati, Claudio Gotti, S. S. Nagorny, M. Pavan, L. Pagnanini, I. Dafinei, P. Gorla, F. Ferroni, C. Tomei, Silvia Capelli, Marco Pallavicini, Massimiliano Nastasi, A. Giuliani, Paolo Carniti, G. Pessina, F. Bellini, C. Zolotarova, M. Beretta, V. Pettinacci, Stefano Pirro, C. Nones, A. Puiu, N. Casali, L. Gironi, M. Biassoni, O. Azzolini, C. Bucci, Miriam Lucio Martinez, Oliviero Cremonesi, S. Morganti, Angelo Cruciani, Ezio Previtali, Stefano Nisi, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPhP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Département de Physique des Particules (ex SPP) (DPP), Azzolini, O, Beeman, J, Bellini, F, Beretta, M, Biassoni, M, Brofferio, C, Bucci, C, Capelli, S, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Clemenza, M, Cremonesi, O, Cruciani, A, Dafinei, I, Di Domizio, S, Ferroni, F, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Keppel, G, Martinez, M, Morganti, S, Nagorny, S, Nastasi, M, Nisi, S, Nones, C, Orlandi, D, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rusconi, C, Schaffner, K, Tomei, C, Vignati, M, and Zolotarova, C

Subjects
Nuclear and High Energy Physics, Physics::Instrumentation and Detectors, Crystal growth, macro-bolometers, Neutrino-less double beta decay, 7. Clean energy, 01 natural sciences, Particle identification, law.invention, Nuclear physics, double-beta decay: (0neutrino), bolometer, law, Double beta decay, 0103 physical sciences, CUPID, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, selenium, Instrumentation, Scintillation, activity report, 010302 applied physics, Physics, background, Bolometer, Detector, zinc, Alpha background, Background level, Gran Sasso, FIS/01 - FISICA SPERIMENTALE, ZnSe, calorimeter: cryogenics, scintillation counter: crystal, Cryogenic detectors, High Energy Physics::Experiment, scintillating cryogenic calorimeter, FIS/04 - FISICA NUCLEARE E SUBNUCLEARE, performance
Abstract

CUPID-0 is the first large mass neutrino-less double beta decay ( 0 ν β β ) experiment based on cryogenic calorimeters with dual read-out of light and heat for background rejection. The detector assembly, consisting of 26 ZnSe crystals, 2 natural and 24 enriched at 95% in 82Se, all coupled with bolometric light detectors, has been constructed respecting very strict protocols and procedures, from the material selection during crystal growth to the new and innovative detector framework, in the attempt to achieve the best performance of the array. The successful construction of the detector lead to promising preliminary results, here presented. The array is in fact taking data underground at LNGS (Italy) since March 2017 and the particle identification, enabled by the light read-out, provides an unprecedented background level, for cryogenic calorimeters, of only 3.2 counts keV − 1 t − 1 yr − 1 in the region of interest of the 0 ν β β search for 82Se, namely around 3 MeV.

Published
2019

41. CUPID-0, challenges and achievements in the struggle of 0-background double-beta decay experiments

Author

L. Gironi, N. Casali, G. Keppel, C. Nones, A. Puiu, D. Orlandi, A. D'Addabbo, I. Dafinei, Oliviero Cremonesi, Claudio Gotti, L. Pattavina, Marco Pallavicini, Lucia Canonica, S. Di Domizio, M. Clemenza, G. Pessina, F. Bellini, S. S. Nagorny, C. Bucci, Lorenzo Cassina, Miriam Lucio Martinez, A. Giuliani, Angelo Cruciani, Ezio Previtali, S. Morganti, Silvia Capelli, Laura Cardani, Stefano Pozzi, Massimiliano Nastasi, A. S. Zolotarova, L. Pagnanini, Jeffrey W. Beeman, M. T. Barrera, O. Azzolini, Paolo Carniti, M. Vignati, V. Palmieri, M. Biassoni, V. Pettinacci, Stefano Pirro, M. Pavan, K. Schäffner, P. Gorla, F. Ferroni, C. Tomei, E. Bossio, M. Beretta, C. Brofferio, C. Rusconi, Stefano Nisi, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Azzolini, O, Barrera, M, Beeman, J, Bellini, F, Beretta, M, Biassoni, M, Bossio, E, Brofferio, C, Bucci, C, Canonica, L, Capelli, S, Cardani, L, Carniti, P, Casali, N, Cassina, L, Clemenza, M, Cremonesi, O, Cruciani, A, D'Addabbo, A, Dafinei, I, Domizio, S, Ferroni, F, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Keppel, G, Martinez, M, Morganti, S, Nagorny, S, Nastasi, M, Nisi, S, Nones, C, Orlandi, D, Pagnanini, L, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rusconi, C, Schäffner, K, Tomei, C, Vignati, M, and Zolotarova, A

Subjects
Nuclear and High Energy Physics, measurement methods, shape analysis, Cryogenic bolometer, 01 natural sciences, Particle identification, law.invention, crystal, Nuclear physics, Crystal, double-beta decay: (0neutrino), bolometer, law, Double beta decay, 0103 physical sciences, Cryogenic bolometers, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, selenium, Instrumentation, background: radioactivity, scintillation counter, Nuclear and High Energy Physic, Physics, Scintillation, 010308 nuclear & particles physics, Detector, Bolometer, zinc, Scintillation counter, Neutrinoless double-beta decay, Zinc selenide scintillator, particle identification, performance, Shape analysis (digital geometry), experimental results
Abstract

The background is the key issue of any experiment searching for the neutrinoless double beta decay (0 ν DBD) and one of the possible solutions is the use of high resolution detectors in which background can be actively discriminated. CUPID-0 is the first 0 ν DBD experiment based on scintillating bolometers able to perform efficient particle identification allowing for background reduction at the unprecedented level of ∼ 10−3 cts/(keV ⋅ kg ⋅ yr). This work makes an overview of the main problems and solutions applied in the construction of the CUPID-0 experimental apparatus, starting from the production of the crystal up to the assembly of the detector. Particular attention is payed to the methods applied to avoid the radio-contamination. The recovery of enriched Se loss along the crystal production cycle is discussed as the main challenge for the budget of this kind of experiments. The good bolometric performance of crystals is emphasized together with supplementary discrimination power offered in the case of ZnSe by the pulse shape analysis, besides the bare scintillation signal. We also make a brief report on detector performance and the results obtained till present which allowed us to establish the world best half-time limit on 82Se 0 ν DBD of >2.4 ⋅ 1024 yr (90% C.I.).

Published
2019

42. Double-beta decay of $^{130}\hbox {Te}$ to the first $0^+$ excited state of $^{130}\hbox {Xe}$ with CUORE-0

Author

Alan R. Smith, Massimiliano Clemenza, Carlo Cosmelli, Oliviero Cremonesi, L. Canonica, L. Marini, Kevin Hickerson, L. Gladstone, M. Faverzani, C. Rosenfeld, R. Hennings-Yeomans, P. Gorla, F. Ferroni, B. X. Zhu, C. Tomei, S. Zucchelli, R. J. Creswick, Emanuele Ferri, Eugene E. Haller, C. Brofferio, James R. Wilson, P. J. Mosteiro, S. Zimmermann, C. Bucci, T. D. Gutierrez, Miriam Lucio Martinez, S. Morganti, D. R. Artusa, Monica Sisti, V. Palmieri, C. J. Davis, L. Carbone, N. Casali, A. Camacho, S. Copello, Eric B. Norman, T. Napolitano, Jeremy S. Cushman, G. Piperno, G. Bari, L. Zanotti, Ke Han, Reina H. Maruyama, Yu. G. Kolomensky, Luigi Cappelli, Davide Chiesa, K. E. Lim, Paolo Carniti, N. D. Scielzo, S. L. Wagaarachchi, Stuart J. Freedman, L. Taffarello, M. Maino, Lorenzo Cassina, Jeffrey W. Beeman, S. Trentalange, M. Biassoni, M. M. Deninno, S. Di Domizio, Y. Mei, I. Dafinei, Guimin Zhang, A. Bersani, A. D'Addabbo, N. Moggi, Simone Capelli, R. W. Kadel, M. Pavan, L. Gironi, F. T. Avignone, Claudio Gotti, H. Z. Huang, B. K. Fujikawa, S. Pirro, Stefano Dell'Oro, Carlo Ligi, Stefano Pozzi, C. Pira, Samuele Sangiorgio, H. W. Wang, G. Keppel, Xi-Guang Cao, A. Leder, F. Bellini, A. Nucciotti, Yu-Gang Ma, T. O'Donnell, A. Caminata, Ezio Previtali, T. I. Banks, K. M. Heeger, M. Vignati, A. Woodcraft, X. Liu, A. Giuliani, G. Fernandes, C. Alduino, F. Orio, Vasundhara Singh, J. Feintzeig, D. Santone, F. Terranova, Ettore Fiorini, E. V. Hansen, N. Chott, M. Tenconi, B. S. Wang, Marco Pallavicini, O. Azzolini, G. Pessina, K. Alfonso, M. L. Di Vacri, C. Nones, C. Rusconi, V. Pettinacci, L. Cardani, Lindley Winslow, L. Pattavina, A. Drobizhev, M. A. Franceschi, A. Giachero, D. Q. Fang, J. L. Ouellet, C. Pagliarone, T. Wise, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, CUORE, and Département de Physique des Particules (ex SPP) (DPhP)

Subjects
Semileptonic decay, topology, Physics and Astronomy (miscellaneous), energy levels: splitting, data acquisition, detector: mass, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 01 natural sciences, energy: transition, CUORE, background: low, double-beta decay: (0neutrino), Double beta decay, 0103 physical sciences, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, Engineering (miscellaneous), Physics, S076H0N, 010308 nuclear & particles physics, excited state: energy, particle: Majorana, semileptonic decay, Excited state, xenon: nuclide, tellurium: nuclide, Neutrino, Atomic physics, Radioactive decay
Abstract

We report on a search for double beta decay of $$^{130}\hbox {Te}$$130Te to the first $$0^{+}$$0+ excited state of $$^{130}\hbox {Xe}$$130Xe using a $$9.8\,\hbox {kg}\cdot \hbox {yr}$$9.8kg·yr exposure of $$^{130}\hbox {Te}$$130Te collected with the CUORE-0 experiment. In this work we exploit different topologies of coincident events to search for both the neutrinoless and two-neutrino double beta decay modes. We find no evidence for either mode and place lower bounds on the half-lives: $$T^{0\nu }_{0^+_1}>7.9\cdot 10^{23}\hbox {yr}$$T01+0ν>7.9·1023yr and $$T^{2\nu }_{0^+_1}>2.4\cdot 10^{23}\hbox {yr}$$T01+2ν>2.4·1023yr ($$90\%\,\hbox {CL}$$90%CL). Combining our results with those obtained by the CUORICINO experiment, we achieve the most stringent constraints available for these processes: $$T^{0\nu }_{0^+_1}>1.4\cdot 10^{24}\hbox {yr}$$T01+0ν>1.4·1024yr and $$T^{2\nu }_{0^+_1}>2.5\cdot 10^{23}\hbox {yr}$$T01+2ν>2.5·1023yr ($$90\%\,\hbox {CL}$$90%CL).

Published
2019

43. Search of the neutrino-less double beta decay of $$^{82}$$ 82 Se into the excited states of $$^{82}$$ 82 Kr with CUPID-0

Author

Angelo Cruciani, Ezio Previtali, E. Bossio, L. Canonica, Lorenzo Cassina, P. Gorla, F. Ferroni, C. Tomei, S. Di Domizio, I. Dafinei, Laura Cardani, Stefano Nisi, Stefano Pozzi, L. Pattavina, V. Pettinacci, Massimiliano Clemenza, M. Vignati, C. Brofferio, Claudio Gotti, Jeffrey W. Beeman, S. Morganti, C. Rusconi, M. Beretta, C. Nones, A. Puiu, V. Palmieri, G. Keppel, O. Azzolini, K. Schäffner, S. Pirro, M. T. Barrera, Oliviero Cremonesi, A. D'Addabbo, Marco Pallavicini, A. Giuliani, L. Gironi, M. Biassoni, G. Pessina, A. S. Zolotarova, S.S. Nagorny, C. Bucci, Miriam Lucio Martinez, N. Casali, L. Pagnanini, D. Orlandi, Paolo Carniti, F. Bellini, Massimiliano Nastasi, M. Pavan, and Simone Capelli

Subjects
Physics, Particle physics, Physics and Astronomy (miscellaneous), 010308 nuclear & particles physics, Double beta decay, Excited state, 0103 physical sciences, Neutrino, 010306 general physics, 01 natural sciences, Engineering (miscellaneous)
Abstract

The CUPID-0 experiment searches for double beta decay using cryogenic calorimeters with double (heat and light) read-out. The detector, consisting of 24 ZnSe crystals 95 $$\%$$ enriched in $$^{82}$$ Se and two natural ZnSe crystals, started data-taking in 2017 at Laboratori Nazionali del Gran Sasso. We present the search for the neutrino-less double beta decay of $$^{82}$$ Se into the 0 $$_1^+$$ , 2 $$_1^+$$ and 2 $$_2^+$$ excited states of $$^{82}$$ Kr with an exposure of 5.74 kg $$\cdot $$ yr (2.24 $$\times $$ 10 $$^{25}$$ emitters $$\cdot $$ yr). We found no evidence of the decays and set the most stringent limits on the widths of these processes: $$\varGamma $$ ( $$^{82}$$ Se $$\rightarrow ^{82}$$ Kr $$_{0_1^+}$$ )8.55 $$\times $$ 10 $$^{-24}$$ yr $$^{-1}$$ , $$\varGamma $$ ( $$^{82}$$ Se $$\rightarrow ^{82}$$ Kr $$_{2_1^+}$$ ) $$\,{

Published
2018

44. 51P Evolution of low HER2 expressions between primary and metastatic breast cancer

Author

P. Tarantino, E. Nicolò, P. Zagami, F. Giugliano, P. Trillo A, A. Marra, D. Trapani, S. Morganti, L. Mazzarella, C. Criscitiello, A. Esposito, and G. Curigliano

Subjects
Oncology, medicine.medical_specialty, Primary (chemistry), business.industry, Internal medicine, Medicine, Hematology, business, medicine.disease, Metastatic breast cancer
Published
2020

45. Performance of the low threshold Optimum Trigger on CUORE data

Author

A. Branca, D. Q. Adams, C. Alduino, K. Alfonso, F. T. Avignone III, O. Azzolini, G. Bari, F. Bellini, G. Benato, M. Biassoni, C. Brofferio, C. Bucci, J. Camilleri, A. Caminata, A. Campani, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Cardani, P. Carniti, N. Casali, D. Chiesa, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, A. D'Addabbo, D. D'Aguanno, I. Dafinei, C. J. Davis, F. Del Corso, S. Dell'Oro, S. Di Domizio, V. Dompè, D. Q. Fang, G. Fantini, M. Faverzani, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, P. Gorla, C. Gotti, T. D. Gutierrez, K. Han, K. M. Heeger, R. G. Huang, H. Z. Huang, J. Johnston, G. Keppel, Yu. G. Kolomensky, C. Ligi, L. Ma, Y. G. Ma, L. Marini, R. H. Maruyama, Y. Mei, N. Moggi, S. Morganti, T. Napolitano, M. Nastasi, J. Nikkel, C. Nones, E. B. Norman, V. Novati, A. Nucciotti, I. Nutini, T. O'Donnell, J. L. Ouellet, C. E. Pagliarone, L. Pagnanini, M. Pallavicini, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, C. Pira, S. Pirro, S. Pozzi, E. Previtali, A. Puiu, C. Rosenfeld, C. Rusconi, M. Sakai, S. Sangiorgio, B. Schmidt, N. D. Scielzo, V. Sharma, V. Singh, M. Sisti, D. Speller, L. Taffarello, F. Terranova, C. Tomei, M. Vignati, S. L. Wagaarachchi, B. S. Wang, B. Welliver, J. Wilson, K. Wilson, L. A. Winslow, L. Zanotti, S. Zimmermann, S. Zucchelli, Branca, A, Adams, D, Alduino, C, Alfonso, K, Avignone III, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Brofferio, C, Bucci, C, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Del Corso, F, Dell'Oro, S, Di Domizio, S, Dompè, V, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Huang, R, Huang, H, Johnston, J, Keppel, G, Kolomensky, Y, Ligi, C, Ma, L, Ma, Y, Marini, L, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, N, Sharma, V, Singh, V, Sisti, M, Speller, D, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Zanotti, L, Zimmermann, S, and Zucchelli, S

Subjects
Physics, History, Particle physics, CUORE, Optimal Trigger, CUORE, low energy, dark matter, WIMP, neutrino, Computer Science Applications, Education
Abstract

The Optimum Trigger (OT) is based on a threshold algorithm applied on waveforms filtered by exploiting the matched filter technique. The OT trigger thresholds improve by 60 – 90% with respect to the thresholds obtained with the standard trigger, ranging between ~ 20 and 100 keV. Low trigger thresholds open the way to Dark Matter searches and to improvements in the neutrinoless double beta decay analysis. Nevertheless, running the OT on CUORE data is demanding from the computational resources point of view. For this reason, the algorithm has been revised and adapted to cope with CUORE data. The work done to implement OT in CUORE and its performances will be discussed.

Published
2020

46. CUPID-0: cryogenic calorimeters with light and heat read-out for $0\nu\beta\beta$ searches

Author

C. Brofferio, L. Pagnanini, Oliviero Cremonesi, Simone Capelli, Stefano Nisi, S. Pirro, Paolo Carniti, C. Gotti, M. T. Barrera, C. Bucci, Miriam Lucio Martinez, D. Orlandi, Jeffrey W. Beeman, Angelo Cruciani, N. Casali, Marco Pallavicini, C. Rusconi, E. Previtali, L. Gironi, Lorenzo Cassina, G. Keppel, Laura Cardani, A. D'Addabbo, Lucia Canonica, V. Palmieri, F. Bellini, O. Azzolini, S. Nagornyg, M. Biassoni, I. Dafinei, V. Pettinacci, A. S. Zolotarova, G. Pessina, S. Morganti, M. Beretta, Sergio Di Domizio, P. Gorla, F. Ferroni, M. Vignati, C. Tomei, K. Schäffner, Massimiliano Nastasi, A. Giuliani, M. Pavan, C. Nones, A. Puiu, S. Pozzi, L. Pattavina, Massimiliano Clemenza, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay

Subjects
Physics, Measurement method, Physics::Instrumentation and Detectors, Detector, zinc, measurement methods, Light signal, helium: background, scintillation counter: cryogenics, Nuclear physics, Amplitude, double-beta decay: (0neutrino), 13. Climate action, Beta (plasma physics), Double beta decay, calorimeter: cryogenics, scintillation counter: crystal, High Energy Physics::Experiment, Sensitivity (control systems), Nuclide, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], selenium: nuclide, nuclide
Abstract

International audience; Cryogenic calorimeters are currently used by experiments searching for neutrino-less double beta decay (0$\nu\beta\beta$). The sensitivity of these experiments is limited by the background coming from $\alpha$ radioactive contaminations. This background can be rejected exploiting the simultaneous read-out of light and heat in scintillating cryogenic calorimeters, because both the amplitude and the time development of the light signal depend on the nature of the particle interacting within. In this paper we present the CUPID-0 detector which represents the first demonstrator of this technique. Exploiting an array of 26 Zn$^{82}$Se scintillating crystals operated as calorimeters and monitored by 31 cryogenic light detectors, CUPID-0 demonstrated the capability to completely reject the $\alpha$ background, paving the way for a next generation experiment searching for 0$\nu\beta\beta$.

Published
2018

47. The β

Author

A, Russomando, M, Schiariti, V, Bocci, M, Colandrea, F, Collamati, M, Cremonesi, M E, Ferrari, P, Ferroli, F, Ghielmetti, R, Ghisini, C M, Grana, C, Mancini Terracciano, M, Marafini, R, Mirabelli, S, Morganti, S, Papi, M, Patanè, G, Pedroli, B, Pollo, E, Solfaroli Camillocci, G, Traini, and R, Faccini

Subjects
Surgery, Computer-Assisted, Occupational Exposure, Positron-Emission Tomography, Humans, Yttrium Radioisotopes, Meningioma, Octreotide, Radiation Dosage, Beta Particles, Injections
Abstract

Radio-guided surgery with βPatients were enrolled on the basis of the standard uptake value (SUV) and the tumour-to-non-tumour activity ratio (TNR) resulted fromEven injecting as low as 1.4 MBq/kg of radiotracer, tumour residuals of 0.1 ml can be detected. A negligible dose to the medical personnel was confirmed.Radio-guided surgery with β

Published
2018

48. First Result on the Neutrinoless Double- β Decay of Se82 with CUPID-0

Author

A. D'Addabbo, G. Keppel, M. Beretta, K. Schäffner, Alexandre Giuliani, S. Pirro, L. Gironi, S. S. Nagorny, Massimiliano Clemenza, P. Gorla, F. Ferroni, C. Tomei, M. Pavan, Paolo Carniti, L. Marini, Claudio Gotti, M. T. Barrera, Oliviero Cremonesi, C. Bucci, Miriam Lucio Martinez, C. Nones, Jeffrey W. Beeman, A. Puiu, V. Palmieri, C. Brofferio, Stefano Nisi, Massimiliano Nastasi, Simone Capelli, S. Di Domizio, Laura Cardani, V. Pettinacci, M. Biassoni, Stefano Pozzi, M. Vignati, S. Morganti, N. Casali, A. S. Zolotarova, Lucia Canonica, F. Reindl, O. Azzolini, C. Rusconi, L. Pagnanini, F. Bellini, Marco Pallavicini, G. Pessina, D. Orlandi, L. Pattavina, Angelo Cruciani, Ezio Previtali, Lorenzo Cassina, and Ioan Dafinei

Subjects
Physics, 010308 nuclear & particles physics, Large array, General Physics and Astronomy, 01 natural sciences, Particle identification, Lower limit, Nuclear physics, MAJORANA, Double beta decay, 0103 physical sciences, Scintillation counter, Neutrino, 010306 general physics, α particles
Abstract

We report the result of the search for neutrinoless double beta decay of Se82 obtained with CUPID-0, the first large array of scintillating ZnSe82 cryogenic calorimeters implementing particle identification. We observe no signal in a 1.83 kg yr Se82 exposure, and we set the most stringent lower limit on the 0νββ Se82 half-life T1/20ν>2.4×1024 yr (90% credible interval), which corresponds to an effective Majorana neutrino mass mββ

Published
2018

49. CUPID-0: the first array of enriched scintillating bolometers for 0\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\nu \beta \beta $$\end{document}νββ decay investigations

Author

O, Azzolini, M T, Barrera, J W, Beeman, F, Bellini, M, Beretta, M, Biassoni, C, Brofferio, C, Bucci, L, Canonica, S, Capelli, L, Cardani, P, Carniti, N, Casali, L, Cassina, M, Clemenza, O, Cremonesi, A, Cruciani, A, D'Addabbo, I, Dafinei, S Di, Domizio, F, Ferroni, L, Gironi, A, Giuliani, P, Gorla, C, Gotti, G, Keppel, M, Martinez, S, Morganti, S, Nagorny, M, Nastasi, S, Nisi, C, Nones, D, Orlandi, L, Pagnanini, M, Pallavicini, V, Palmieri, L, Pattavina, M, Pavan, G, Pessina, V, Pettinacci, S, Pirro, S, Pozzi, E, Previtali, A, Puiu, F, Reindl, C, Rusconi, K, Schäffner, C, Tomei, M, Vignati, and A, Zolotarova

Subjects
Special Article - Tools for Experiment and Theory
Abstract

The CUPID-0 detector hosted at the Laboratori Nazionali del Gran Sasso, Italy, is the first large array of enriched scintillating cryogenic detectors for the investigation of \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$^{82}$$\end{document}82Se neutrinoless double-beta decay (\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$0\nu \beta \beta $$\end{document}0νββ). CUPID-0 aims at measuring a background index in the region of interest (RoI) for \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$0\nu \beta \beta $$\end{document}0νββ at the level of 10\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$^{-3}$$\end{document}-3 counts/(keV kg years), the lowest value ever measured using cryogenic detectors. CUPID-0 operates an array of Zn\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$^{82}$$\end{document}82Se scintillating bolometers coupled with bolometric light detectors, with a state of the art technology for background suppression and thorough protocols and procedures for the detector preparation and construction. In this paper, the different phases of the detector design and construction will be presented, from the material selection (for the absorber production) to the new and innovative detector structure. The successful construction of the detector lead to promising preliminary detector performance which is discussed here.

Published
2018

50. CUPID-0: the first array of enriched scintillating bolometers for 0 $$\nu \beta \beta $$ ν β β decay investigations

Author

Massimiliano Clemenza, O. Azzolini, S. Di Domizio, Laura Cardani, Stefano Pozzi, S. Pirro, C. Brofferio, Massimiliano Nastasi, L. Canonica, V. Palmieri, M. Vignati, C. Bucci, Miriam Lucio Martinez, N. Casali, C. Rusconi, M. Biassoni, G. Keppel, I. Dafinei, Jeffrey W. Beeman, L. Gironi, Stefano Nisi, M. Pavan, F. Bellini, L. Pattavina, A. Cruciani, A. S. Zolotarova, M. Beretta, C. Nones, A. Puiu, P. Gorla, F. Ferroni, C. Tomei, A. Giuliani, F. Reindl, D. Orlandi, Lorenzo Cassina, Marco Pallavicini, K. Schäffner, G. Pessina, Oliviero Cremonesi, Claudio Gotti, M. T. Barrera, L. Pagnanini, Simone Capelli, Paolo Carniti, A. D'Addabbo, S. Morganti, Ezio Previtali, V. Pettinacci, and S. S. Nagorny

Subjects
Physics, Physics and Astronomy (miscellaneous), Physics::Instrumentation and Detectors, 010308 nuclear & particles physics, Bolometer, Large array, Detector, Cryogenics, 01 natural sciences, law.invention, Nuclear physics, law, 0103 physical sciences, Background suppression, Scintillation counter, High Energy Physics::Experiment, Production (computer science), 010306 general physics, Engineering (miscellaneous)
Abstract

The CUPID-0 detector hosted at the Laboratori Nazionali del Gran Sasso, Italy, is the first large array of enriched scintillating cryogenic detectors for the investigation of $$^{82}$$ Se neutrinoless double-beta decay ( $$0\nu \beta \beta $$ ). CUPID-0 aims at measuring a background index in the region of interest (RoI) for $$0\nu \beta \beta $$ at the level of 10 $$^{-3}$$ counts/(keV kg years), the lowest value ever measured using cryogenic detectors. CUPID-0 operates an array of Zn $$^{82}$$ Se scintillating bolometers coupled with bolometric light detectors, with a state of the art technology for background suppression and thorough protocols and procedures for the detector preparation and construction. In this paper, the different phases of the detector design and construction will be presented, from the material selection (for the absorber production) to the new and innovative detector structure. The successful construction of the detector lead to promising preliminary detector performance which is discussed here.

Published
2018

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